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See detailLa gestion de la diversité dans les entreprises et les organisations
Cornet, Annie ULg

Conference (2011)

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See detailEtat de nécessité (et ses liens avec la légitime défense)
Forthomme, Marie ULg

in Postal Memorialis (2011), E 153

A l'instar de la légitime défense, de l'ordre ou l'autorisation de la loi et du commandement légal de l'autorité, l'état de nécessité constitue une des causes de justification objectives retenues en droit ... [more ▼]

A l'instar de la légitime défense, de l'ordre ou l'autorisation de la loi et du commandement légal de l'autorité, l'état de nécessité constitue une des causes de justification objectives retenues en droit belge. La présente contribution analyse l'état de nécessité, tant sous l'angle de ses conditions d'existence que sous ses aspects procéduraux (y compris internationaux), en effectuant des liens avec la légitime défense. [less ▲]

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See detailOn the spectral bands measurements for combustion monitoring
Arias, Luis; Torres, S; Sbarbaro, D et al

in Combustion and Flame (2011), 158

In this work, spatial–spectral experimental issues affecting the detection of radical emissions in a natural gas flame are discussed and studied by a radiometric analysis of the flame spectral emission ... [more ▼]

In this work, spatial–spectral experimental issues affecting the detection of radical emissions in a natural gas flame are discussed and studied by a radiometric analysis of the flame spectral emission. As results of this analysis, Local and Global Spectral Radiation Measurements (LSRM and GSRM respectively) techniques are proposed, and guidelines for selecting the radical emission bands and spatial location of photodetectors are given. Two types of experiments have been performed in order to demonstrate the reliability of the GSRM technique for combustion characterization. In the first experiment, the LSRM and the GSRM have been implemented by using a home made sensor array, based on silicon photodiodes, for sensing the excited CH* and C2 radicals in a natural gas flame. It has been experimentally that by using the GSRM, the signal’s dispersion can be reduced to about 86% for the CH* and 76% for the C2 with respect to the obtained values with LSRM methodology. In the second experiment, the GSRM technique has been applied for sensing the CH* and C2 radicals, where it has been found that the signals emissions ratio C2/CH* provides a good indicator of the thermal combustion efficiency and the CO pollutants emissions, with small dispersion. Thus, the GSRM technique has corroborated the usefulness of that ratio for combustion monitoring. [less ▲]

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See detailDiagnostic value of neurotrophin expression in malignant pleural effusions
DUYSINX, Bernard ULg; PAULUS, Aurore ULg; HEINEN, Vincent ULg et al

in Experimental and Therapeutic Medicine (2011), 2(5), 941-946

Neurotrophins (NTs) modulate the growth of human malignancies, including lung cancers. Our prospective study evaluated the accuracy of pleural NTs [nerve growth factor, brain-derived neurotrophic factor ... [more ▼]

Neurotrophins (NTs) modulate the growth of human malignancies, including lung cancers. Our prospective study evaluated the accuracy of pleural NTs [nerve growth factor, brain-derived neurotrophic factor (BDNF), neurotrophin 3 (nT3) and 4 (nT4)] levels for differentiating benign from malignant pleural exudates. Levels of NTs were measured by ELISA in 170 patients with non-neutrophilic (<50%) exudative benign or malignant pleurisies diagnosed by pleuroscopy. Fifty-nine benign (9 infections and 50 inflammatory diseases) and 111 malignant (50 extrathoracic tumors, 51 lung cancers and 10 mesotheliomas) pleural exudates were diagnosed by thoracoscopy. Levels of BDNF were significantly higher in malignant than in benign effusions [17 pg/ml (0-367) vs. 8 pg/ml (0-51), p<0.05]. ROC analysis showed an area under the curve of 0.609 (p=0.012; best threshold 44 pg/ml). Pleural BDNF levels were significantly higher in pleural metastasis of pulmonary tumors and in mesothelioma than in pleural benign effusions. Finally, a higher proportion of pleural nT3 was detected in squamous cell lung carcinoma in comparison to that in non-squamous cell lung carcinoma (72.7 vs. 10%, p<0.0001). NTs and particularly BDNF may play a role in the pathogenesis of malignant pleural effusions. [less ▲]

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See detailUn projet belge de recours collectif au regard des modèles espagnol et québécois
Frankignoul, Laurent ULg

in Revue de la Faculté de Droit de l'Université de Liège (2011)

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See detailBacterial diversity of field-caught mosquitoes, Aedes albopictus and Aedes aegypti, from different geographic regions of Madagascar.
Zouache, Karima; Raharimalala, Fara Nantenaina ULg; Raquin, Vincent et al

in FEMS Microbiology Ecology (2011)

Symbiotic bacteria are known to play important roles in the biology of insects, but the current knowledge of bacterial communities associated with mosquitoes is very limited and consequently their ... [more ▼]

Symbiotic bacteria are known to play important roles in the biology of insects, but the current knowledge of bacterial communities associated with mosquitoes is very limited and consequently their contribution to host behaviors is mostly unknown. In this study, we explored the composition and diversity of mosquito-associated bacteria in relation with mosquitoes’ habitats. Wild Aedes albopictus and Aedes aegypti were collected in three different geographic regions of Madagascar. Culturing methods and denaturing gradient gel electrophoresis (DGGE) and sequencing of the rrs amplicons revealed that Proteobacteria and Firmicutes were the major phyla. Isolated bacterial genera were dominated by Bacillus, followed by Acinetobacter, Agrobacterium and Enterobacter. Common DGGE bands belonged to Acinetobacter, Asaia, Delftia, Pseudomonas, Enterobacteriaceae and an uncultured Gammaproteobacterium. Double infection by maternally inherited Wolbachia pipientis prevailed in 98% of males (n = 272) and 99% of females (n = 413); few individuals were found to be monoinfected withWolbachia wAlbB strain. Bacterial diversity (Shannon–Weaver and Simpson indices) differed significantly per habitat whereas evenness (Pielou index) was similar. Overall, the bacterial composition and diversity were influenced both by the sex of individuals and by the environment inhabited by the mosquitoes; the latter might be related to both the vegetation and the animal host populations that Aedes used as food sources. [less ▲]

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See detailCompte-rendu de l'ouvrage de I. Leventi, Chr. Mitsopoulou, Ιερά και λατρείες της Δήμητρας στον αρχαἰο ελληνικό κόσμο
Paul, Stéphanie ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (2011), 24

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See detailHow they became the human face of climate change. Research and policy interactions in the birth of the ‘environmental migration’ concept.
Gemenne, François ULg

in Piguet, Etienne; Pécoud, Antoine; De Guchteneire, Paul (Eds.) Migration and Climate Change (2011)

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See detailComment j'explore... Une arythmie ventriculaire chez le sportif
Tombeux, C.; MELON, Pierre ULg; Close, P. et al

in Revue Médicale de Liège (2011), 66(1), 30-33

How I explore : ventricular arrhythmhmias in athletes <br />SUMMARY : Documented ventricular tachyarrhythmias or related symptoms need meticulous cardiac investigations. The mechanism of ventricular ... [more ▼]

How I explore : ventricular arrhythmhmias in athletes <br />SUMMARY : Documented ventricular tachyarrhythmias or related symptoms need meticulous cardiac investigations. The mechanism of ventricular arrhythmia must be defined. The prognosis is related to underlying cardiac electrical or structural disorders. In the absence of cardiovascular abnormalities, the prognosis is good. No disqualification to competitive activity is required in most cases. Assessment of the risk of sudden death remains a continuing challenge in athletes. This article reviews the diagnostic and therapeutic approaches of ventricular arrhythmias encountered in trained athletes. [less ▲]

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See detailNew Methodology to detect toxin-GPCR binding by MALDI-TOF Mass Spectrometry
Echterbille, Julien ULg; De Pauw, Edwin ULg; Gilles, Nicolas et al

Poster (2011)

Introduction More than 50 thousands of venomous species are currently indexed in the world. Each of their venoms is composed of 200 to 1000 different toxins which potentially exhibit a high selectivity ... [more ▼]

Introduction More than 50 thousands of venomous species are currently indexed in the world. Each of their venoms is composed of 200 to 1000 different toxins which potentially exhibit a high selectivity for membrane receptors such as ionic channels or G-protein coupled receptors (GPCRs). GPCRs constitute the larger family of receptors since around 800 different kinds of them are knows. GPCRs are the target of around 30% of the current pharmacopeia drugs. Notable examples include Novartis’s Zelnorm, Eli Lilly’s Zyprexa and Schering-Plough’s Clarinex used to treat constipation, schizophrenia and allergies, respectively. Finding new GPCRs ligands appears of prime interest to design new pharmacological tools and potentially discover the drugs of our future. Interestingly, several toxins from venoms have already been described to bind to this particular family of receptor, opening the way to the discovery of new peptide drugs from animal venoms1-2. This work presents a pioneering MALDI-TOF/TOF based strategy to fish new GPCRs ligands from complex mixtures such as venom fractions. Methods The proof of concept of this methodology was built by studying the binding of [Arg8]-vasopressin (AVP) on type 2-vasopressin receptor (V2). Experimentally, fragments of cellular membranes over-expressing V2 receptors were incubated with cone snail’s venom fraction (~30 peptide toxins) doped by a small amount of AVP. After 2 hours incubation, free and bound fractions were carefully purified with a combination of centrifugation and micro column purifications. Samples were finally analyzed with a Bruker Ultraflex II MALDI-TOF/TOF mass spectrometer and the resulting spectra were interpreted with FlexAnalysis (v3.0), BioTools (v3.2) and SequenceEditor (v3.2) bioinformatics’ softwares from Bruker Daltonics. Preliminary data After the incubation of cellular membranes overexpressing V2 GPCR with a complex mixture of peptides doped by AVP, we clearly detect that the only V2 ligand present in the fraction was the AVP. Our result demonstrates the possibility to identify a ligand of GPCRs from a complex peptide mixture, such as venom fractions. Contrary to radiobinding, this approach allows detecting the direct binding of the toxin and does not imply to know a ligand of the studied GPCR before starting the experiments. This opens the way to the deorphanization of receptors (180 orphans GPCRs over 800). Moreover, since the new ligand is detected by mass spectrometry, it is directly identified from the mixture, without additional purification. Its structural characterization can be directly performed by de novo sequencing experiments. The drawback of our approach is the very long (but crucial!) sample preparation as each sample requires 2 purification steps (for both free and bound fraction). The next step of our work will be the automation of the procedure to allow a high-throughput screening of venom fractions on different GPCRs and the discovery of new ligands. Novel aspect GPCR’s ligands discovery by MALDI-TOF/TOF based techniques: a new pharmacological tool. 1 Quinton, L. et al. Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the a1A-adrenoceptor. British Journal of Pharmacology 159, 316-325 (2010). 2 Rouget, C. et al. Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors. British Journal of Pharmacology 161, 1361-1374, doi:10.1111/j.1476-5381.2010.00966.x (2010). [less ▲]

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See detailMesoporous SiO2 thin films containing ZnO photoluminescent nanoparticles. Simultaneous SAXS / WAXS / Ellipsometry investigations
Krins, Natacha ULg; Bass, J. D.; Julián-López, B. et al

in Journal of Materials Chemistry (2011), 21

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See detailMotives to begin physical education studies. Comparative analysis in Algeria and Wallonia
Kerfes, Nabil; Alem, Jaouad; Cloes, Marc ULg

Conference (2011)

There are many reasons explaining why students choose one professional project and/or an academic programme. Usually, they consider higher education according to various aspects focusing on the content of ... [more ▼]

There are many reasons explaining why students choose one professional project and/or an academic programme. Usually, they consider higher education according to various aspects focusing on the content of the programme as well as on professions to which the latter leads. This study is in the field on comparative education. It offers a comprehensive reading of two education systems in a spirit of openness and expansion of knowledge. With inspiration from two studies conducted in the education of physical educators in very different cultural contexts (Research Group MJS, 1993, for Algeria – Groupe de recherche interuniversitaire, 2003, for French-speaking Belgium), we have assumed that the students’ motives for registering in studies in physical education should differ considerably. The purpose of this research has therefore been to determine the reasons motivating students to begin a physical education programme at the university or at a non university context. Our research was based, firstly, on the analysis of official texts concerning the organization of higher education in the field of physical education and, secondly, on data collected from the actions involved in four educational institutions, two in the Algiers region and two in the Liege region. In both cultural contexts, one institution belonged to one university and the other one was organized in a non university context. Our results relate to a total sample of 290 subjects (40 members of teaching staffs, 108 students and 142 graduates). The staff members were interviewed while the subjects of two other groups have responded to questionnaires. The Arabic version of each instrument was translated from an original French version. One expert has assured the validity check. In this paper, we are focusing our attention on the analysis of the responses provided by the three types of actors to a question aiming to identify, through four levels Lickert scales, the degree of importance accorded by subject to nine reasons of registration for studies in physical education. Answer were encoded in a computer database and processed using the Statistica software (Stat Soft, 2006). No significant difference was identified when comparing the answers of respondents. However, we noticed that the love of sport and the desire to do sport belonged to the most important reasons for the registration of the new students for training programs in physical education. Cultural context does not seem to affect the opinions of the subjects. [less ▲]

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See detailReview of Dear Charles, Dear Janet: Frame and Brasch in Correspondence
Delrez, Marc ULg

in Commonwealth : Essays and Studies (2011), 33.2(Spring 2011), 151-153

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See detailGéographie, tourisme et tourisme rural : une critique de quatre ouvrages
Dubois, Charline ULg

in Bulletin de la Société Géographique de Liège (2011), 57

Four books studying either tourism in a global sense or more specifically rural tourism, have been explored and subjected to some reviews: The Geography of Tourism and Recreation - Environment, Place and ... [more ▼]

Four books studying either tourism in a global sense or more specifically rural tourism, have been explored and subjected to some reviews: The Geography of Tourism and Recreation - Environment, Place and Space by C. Michael Hall and Stephen J. Page (2005), Rural Tourism and Sustainable Business by Derek Hall, Irene Kirkpatrick and Morag Mitchell (2005), Tourism and tourism spaces by Gareth Shaw and Allan M. Williams (2004), and Rural Tourism and Recreation: Principles to Practice by Lesley Roberts and Derek Hall (2001). After the step of synthesis of each one, their own developments and their utilities will be discussed. [less ▲]

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See detailMiradas que se cruzan desde España. El entusiasmo de Manuel Vázquez Montalbán y la crítica de Ignacio Vidal-Folch
Vanden Berghe, Kristine ULg

in Vanden Berghe, Kristine; Huffshmid, Anne; Lefere, Robin (Eds.) EL EZLN y sus intérpretes. Resonancias del zapatismo en la academia y en la literatura. (2011)

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See detailContrasted views on environmental migration: the case of Tuvaluan migration to New Zealand
Shen, Shawn; Gemenne, François ULg

in International Migration (2011), 49

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See detailVariations sur un homme de valeur(s)
Denis, Benoît ULg

in Sindaco, Sarah (Ed.) Jean-Marie Klinkenberg : un homme d'(inter)action (2011)

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See detailInfluence of the alveoli slopes on the discharge capacity of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Proceedings of the 34th IAHR world congress (2011)

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key ... [more ▼]

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key Weir has already been well demonstrated, the definition of its optimal geometry has been still poorly approached. In order to improve the design of the complex geometry of this structure, the study of the influence of the mean geometrical parameters on the discharge capacity is an essential stage. Following a former experimental study of the flow over Piano Key Weirs, highlighting the mean influence of three geometrical parameters, this paper presents the results of an experimental parametric study. These results highlight the influence of the alveoli bottom slopes on the Piano Key Weir release capacity. Comparisons with numerical and analytical results, as well as design advices are also provided. [less ▲]

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