References of "2011"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailMetformin and lactic acidosis.
SCHEEN, André ULg

in Acta Clinica Belgica (2011), 66(5), 329-31

Detailed reference viewed: 42 (1 ULg)
Full Text
Peer Reviewed
See detailContrasted views on environmental migration: the case of Tuvaluan migration to New Zealand
Shen, Shawn; Gemenne, François ULg

in International Migration (2011), 49

Detailed reference viewed: 22 (1 ULg)
See detailNanobodies as structural probes to investigate the mechanism of fibril formation by the amyloidogenic variants of human lysozyme
Dumont, Janice ULg; Pardon, Els; Aumont-Nicaise, Magalie et al

Poster (2011)

Six variants of human lysozyme (single-point mutations I56T, F57I, W64R, D67H and double mutations F57I/T70N, W112R/T70N) are associated with a hereditary non-neuropathic systemic amyloidose. These ... [more ▼]

Six variants of human lysozyme (single-point mutations I56T, F57I, W64R, D67H and double mutations F57I/T70N, W112R/T70N) are associated with a hereditary non-neuropathic systemic amyloidose. These proteins form extracellular amyloid fibrils that deposit in a wide range of tissues and organs such as liver, spleen and kidneys where they cause damages [1]. It was shown that the D67H and I56T mutations cause a loss in stability and more particularly a loss of global cooperativity of protein [1]. Consequently, under physiologically relevant conditions, these variants can transiently populate a partially unfolded state in which the beta-domain and the C-helix are cooperatively unfolded while the rest of the protein remains native like [1]. The formation of intermolecular interactions between the regions that are unfolded in this intermediate state is likely to be a fundamental trigger of the aggregation process that ultimately leads to the formation and deposition of fibrils in tissues. We have also shown that the binding of three variable domain of camelid antibodies or (VHHs) - raised against the wild type human lysozyme inhibit in vitro the formation of amyloid fibrils by the lysozyme variants. These three VHHs bind on different regions of lysozyme and act as amyloid fibrils inhibitor through different mechanisms [2, 3, and unpublished results]. In the present work, sixteen new VHHs specific of human lysozyme have been generated. Competition experiments have shown that they bind to five non overlapping epitopes. We have demonstrated that five of these new VHHs are able to bind lysozyme in conditions used for amyloid fibril formation, and interestingly two of them recognize two epitopes that are different from those of the three VHHs previously characterized [2, 3, and unpublished results]. The effects of these new VHHs on the properties of lysozyme variants such as activity, stability, cooperativity and aggregation will be discussed. [less ▲]

Detailed reference viewed: 59 (1 ULg)
Full Text
Peer Reviewed
See detailInfluence of the alveoli slopes on the discharge capacity of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Proceedings of the 34th IAHR world congress (2011)

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key ... [more ▼]

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key Weir has already been well demonstrated, the definition of its optimal geometry has been still poorly approached. In order to improve the design of the complex geometry of this structure, the study of the influence of the mean geometrical parameters on the discharge capacity is an essential stage. Following a former experimental study of the flow over Piano Key Weirs, highlighting the mean influence of three geometrical parameters, this paper presents the results of an experimental parametric study. These results highlight the influence of the alveoli bottom slopes on the Piano Key Weir release capacity. Comparisons with numerical and analytical results, as well as design advices are also provided. [less ▲]

Detailed reference viewed: 37 (2 ULg)
Full Text
Peer Reviewed
See detailImprovement of the UNIQUAC combinatorial-entropy term by adjusting the standard segment
Bronneberg, Rob; Pfennig, Andreas ULg

in Journal of Chemical & Engineering Data (2011), 56

Detailed reference viewed: 23 (9 ULg)
Full Text
See detailPartenariats en matière de lutte contre l'érosion hydrique et les inondations par ruissellement
Dogot, Thomas ULg

in Réseau wallon de Développement Rural (Ed.) « Erosion, ruissellement, coulées boueuses et inondations » : Actes de l’Atelier régional – Meux, 13 mai 2011 (2011)

Detailed reference viewed: 27 (6 ULg)
Full Text
See detailRobust maximum weighted independent-set problems on interval graphs
Talla Nobibon, Fabrice ULg; Leus, Roel

Report (2011)

We study the maximum weighted independent-set problem on interval graphs with uncertainty on the vertex weights. We use the absolute robustness criterion and the min-max regret criterion to evaluate ... [more ▼]

We study the maximum weighted independent-set problem on interval graphs with uncertainty on the vertex weights. We use the absolute robustness criterion and the min-max regret criterion to evaluate solutions. For a discrete scenario set, we nd that the problem is NP-hard for each of the robustness criteria; we also provide pseudo-polynomial time algorithms when there is a constant number of scenarios and show that the problem is strongly NP-hard when the set of scenarios is unbounded. When the scenario set is a Cartesian product, we prove that the problem is equivalent to a maximum weighted independent-set problem on the same interval graph but without uncertainty for the rst objective function and that the scenario set can be reduced for the second objective function. [less ▲]

Detailed reference viewed: 28 (1 ULg)
Full Text
Peer Reviewed
See detailOrganochlorine pesticides, polychlorinated biphenyls and trace elements in wild European sea bass (Dicentrarchus labrax) off European estuaries
Schnitzler, Joseph ULg; Thomé, Jean-Pierre ULg; Lepage, Mario et al

in Science of the Total Environment (2011), 409(19), 3680-3686

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like dichloro-diphenyl-trichloroethane (DDTs), hexachlorocyclohexanes (HCHs), aldrin, dieldrin and trace elements (Cd, Cu, Se, Pb, Zn and Hg ... [more ▼]

Polychlorinated biphenyls (PCBs) and organochlorine pesticides like dichloro-diphenyl-trichloroethane (DDTs), hexachlorocyclohexanes (HCHs), aldrin, dieldrin and trace elements (Cd, Cu, Se, Pb, Zn and Hg) were analysed in the muscle of European sea bass (Dicentrarchus labrax) sampled in Atlantic coastal regions near several important European river mouths (Gironde, Charente, Loire, Seine and Scheldt). High contamination levels were measured in the muscles of European sea bass sampled in the coastal regions near those river mouths (e.g. Σ ICES PCB=133–10,478 μg kg−1 lw and Hg=250–2000 μg kg−1 dw). The Scheldt and the Seine are still among the most contaminated estuaries in Europe. Each region presented their specific contamination patterns reflecting different sources due to the input of the respective rivers. As fish and fishery products are the main contributors of the total dietary intake of organochlorinated pollutants, regular consumption of European sea bass with the reported contamination levels may represent a significant exposure route for the general human population. [less ▲]

Detailed reference viewed: 84 (22 ULg)
Full Text
Peer Reviewed
See detailSimulation von Extraktionskolonnen in der industriellen Praxis
Buchbender, Florian; Schmidt, Markus; Pfennig, Andreas ULg et al

in Chemical Engineering and Technology (2011), 84(4), 540-546

Peer Reviewed
See detailThe Producerist Narrative in Right-wing Flanders
Jamin, Jérôme ULg

Conference (2011)

Detailed reference viewed: 10 (1 ULg)
Peer Reviewed
See detailDescription of the bone-remodeling pattern after socket preservation procedures in human: a methodological study
LAMBERT, France ULg; VINCENT, Kim ULg; VANHOUTTE, Vanessa ULg et al

Poster (2011)

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review ... [more ▼]

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review. Multiple surgical protocols using biomaterials are proposed in order to limit the typical postextraction bone resorption. However, because of the heterogeneity of the studies and, more specifically, of the assessment methods, it is difficult to assert the superiority of one technique over another. Aim: The objective of this study was to develop a new radiographic method to assess alveolar bone remodeling after socket preservation procedures. Methods: Sixteen extraction sites (in 14 patients) localized in the upper anterior maxilla were treated with bovine hydroxyapatite (0.25–1mm particles) and a saddled connective tissue graft. A radiographic 3-dimensional assessment of the hard tissues was performed at baseline and at 3 months after the procedure. Standardized horizontal measurements were taken at three corono apical levels ( 2, 5, and 9mm) and at three mesio-diatal level (Mesial, Center, and Distal) in the buccal and palatal aspects. Vertical measurements were also recorded in nine regions over the top of the alveolar crest. Results: Extraction socket-preservation technique assessed in the present study significantly reduced horizontal bone remodeling. The horizontal dimension of the crest decreased by 1.6mm (20%) in the cervical regions ( 2mm level), experienced a moderate decrease of 1mm (12%) at the 5mm level, and experienced a very low decrease of 0.5mm(6%) in the apical ( 8mm) level. The losses were always significantly higher in the buccal than in the palatal aspect. Buccally, the maximal bone remodeling at the cervical level remained below 1mm. Vertical bone resorption was homogeneous and was < 1mm in the nine measured regions. Conclusions and clinical implications: The radiographic measuring methodology proved to be accurate and reproducible. It can be applied in other clinical settings. Moreover, the surgical procedure evaluated in the present study, significantly limits the postextraction buccal bone remodeling compared with the data found in the literature for untreated extraction socket in the aesthetic area. However, a complete inhibition of the bone remodeling was not reached and the authors suggest a surgical technique using a ‘‘saddled’’ connective tissue graft to thicken buccal soft tissue biotype and consequently compensate for cervical bone loss. [less ▲]

Detailed reference viewed: 29 (3 ULg)
Full Text
Peer Reviewed
See detailCarbon and nitrogen flows during a bloom of the coccolithophore Emiliania huxleyi: Modelling a mesocosm experiment
Joassin, Pascal ULg; Delille, Bruno ULg; Soetaert, Karline et al

in Journal of Marine Systems (2011), 85

A dynamic model has been developed to represent biogeochemical variables and processes observed during experimental blooms of the coccolithophore Emiliania huxleyi induced inmesocosms over a period of 23 ... [more ▼]

A dynamic model has been developed to represent biogeochemical variables and processes observed during experimental blooms of the coccolithophore Emiliania huxleyi induced inmesocosms over a period of 23 days. The model describes carbon (C), nitrogen (N), and phosphorus (P) cycling through E. huxleyi and the microbial loop, and computes pH and the partial pressure of carbon dioxide (pCO2) from dissolved inorganic carbon (DIC) and total alkalinity (TA). The main innovations are: 1) the representation of E. huxleyi dynamics using an unbalanced growthmodel in carbon and nitrogen, 2) the gathering of formulations describing typical processes involved in the export of carbon such as primary production, calcification, cellular dissolved organic carbon (DOC) excretion, transparent exopolymer (TEP) formation and viral lyses, and 3) an original and validated representation of the calcification process as a function of the net primary production with a modulation by the intra-cellular N:C ratio mimicking the effect of nutrients limitation on the onset of calcification. It is shown that this new mathematical formulation of calcification provides a better representation of the dynamics of TA, DIC and calcification rates derived from experimental data compared to classicaly used formulations (e.g. function of biomass or of net primary production without anymodulation term). In a first step, the model has been applied to the simulations of present pCO2 conditions. It adequately reproduces the observations for chemical and biological variables and provides an overall view of carbon and nitrogen dynamics. Carbon and nitrogen budgets are derived from the model for the different phases of the bloom, highlighting three distinct phases, reflecting the evolution of the cellular C:N ratio and the interaction between hosts and viruses. During the first phase, inorganic nutrients are massively consumed by E. huxleyi increasing its biomass. Uptakes of carbon and nitrogen are maintained at a constant ratio. The second phase is triggered by the exhaustion of phosphate (PO4 3−). Uptake of carbon and nitrogen being uncoupled, the cellular C:N ratio of E. huxleyi increases. This stimulates the active release of DOC, acting as precursors for TEP. The third phase is characterised by an enhancement of the phytoplankton mortality due to viral lysis. A huge amount of DOC has been accumulated in the mesocosm. [less ▲]

Detailed reference viewed: 157 (11 ULg)
Full Text
Peer Reviewed
See detailTechniques de séchage des starters lactiques et mécanismes affectant la viabilité cellulaire suite à la lyophilisation
Coulibaly, Ibourahema ULg; Dubois Dauphin, Robin ULg; Danthine, Sabine ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2011), 15(2), 287-299

Detailed reference viewed: 58 (14 ULg)
Full Text
Peer Reviewed
See detailQuantitative food webs of herbivore and related beneficial community in non–crop and crop habitats
Alhmedi, Ammar; Haubruge, Eric ULg; D’Hoedt, Sandrine et al

in Biological Control (2011), 58

Detailed reference viewed: 34 (5 ULg)
Full Text
Peer Reviewed
See detailCompetitive facility location problem with attractiveness adjustment of the follower: A bilevel programming model and its solution
Kucukaydin, Hande ULg; Aras, Necati; Altinel, I. Kuban

in European Journal of Operational Research (2011), 208(3), 206-220

We are concerned with a problem in which a firm or franchise enters a market by locating new facilities where there are existing facilities belonging to a competitor. The firm aims at finding the location ... [more ▼]

We are concerned with a problem in which a firm or franchise enters a market by locating new facilities where there are existing facilities belonging to a competitor. The firm aims at finding the location and attractiveness of each facility to be opened so as to maximize its profit. The competitor, on the other hand, can react by adjusting the attractiveness of its existing facilities with the objective of maximizing its own profit. The demand is assumed to be aggregated at certain points in the plane and the facilities of the firm can be located at predetermined candidate sites. We employ Huff's gravity-based rule in modeling the behavior of the customers where the fraction of customers at a demand point that visit a certain facility is proportional to the facility attractiveness and inversely proportional to the distance between the facility site and demand point. We formulate a bilevel mixed-integer nonlinear programming model where the firm entering the market is the leader and the competitor is the follower. In order to find the optimal solution of this model, we convert it into an equivalent one-level mixed-integer nonlinear program so that it can be solved by global optimization methods. Apart from reporting computational results obtained on a set of randomly generated instances, we also compute the benefit the leader firm derives from anticipating the competitor's reaction of adjusting the attractiveness levels of its facilities. The results on the test instances indicate that the benefit is 58.33% on the average. [less ▲]

Detailed reference viewed: 46 (7 ULg)
Full Text
Peer Reviewed
See detailCoordination of verbal dependents in Old French : Coordination as a specified juxtaposition or apposition
Mazziotta, Nicolas ULg

in Gerdes, Kim; Hajičova, Eva; Wanner, Leo (Eds.) Proceedings of Depling 2011, International Conference on Dependency Linguistics, Barcelona (2011)

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detail1D numerical modeling of the flow over a Piano Key Weir
Erpicum, Sébastien ULg; Machiels, Olivier ULg; Archambeau, Pierre ULg et al

in Erpicum, Sébastien; Laugier, Frédéric; Boillat, Jean Louis (Eds.) et al Labyrinth and Piano Key Weirs - PKW 2011 (2011)

Because of the PK-Weir geometric specificities, its hydraulic capacity remains difficult to predict without using experimental techniques. A 1D numerical model of the flow over a PK-Weir has been ... [more ▼]

Because of the PK-Weir geometric specificities, its hydraulic capacity remains difficult to predict without using experimental techniques. A 1D numerical model of the flow over a PK-Weir has been developed at the Research unit HACH at the University of Liege. It is based on a 1D modeling of the inlet and the outlet separately, with a single upstream reservoir and interactions between both flows by exchange of mass and momentum along the lateral crest. The comparison of the numerical results with various experimental data showed the ability of the numerical model to predict with reasonable accuracy the release capacity of a PK-Weir, whatever its geometry. The tests of the solver enable to highlight the significant influence of the inlet and outlet width on the weir release capacity. They also suggest that improvements of the numerical model may lie in the evaluation of the discharge coefficient of the lateral crest. [less ▲]

Detailed reference viewed: 112 (10 ULg)
Full Text
Peer Reviewed
See detailZinc complexes with 1,2,4-triazole functionalized amino acid derivatives: Synthesis, structure and b-lactamase assay
Naik, Anil; Beck, Joséphine; Dîrtu, Marinela et al

in Inorganica Chimica Acta (2011), 368

Coordinating abilities of 4R-1,2,4-triazole derivatives (R = glycine ethyl ester (L1), glycine (L2), diethylamino malonate (L3), methionine (L4) and diethyl aminomethylphosphonate (L5)) towards ZnII ions ... [more ▼]

Coordinating abilities of 4R-1,2,4-triazole derivatives (R = glycine ethyl ester (L1), glycine (L2), diethylamino malonate (L3), methionine (L4) and diethyl aminomethylphosphonate (L5)) towards ZnII ions have been studied in solution, in solid state and versus three zinc-b-lactamases. The crystal structure of [Zn3(L4)6(H2O)6] (6) is described; it is the first crystal structure involving a 1,2,4-triazole functionalized methionine. It forms a trinuclear complex with central zinc octahedrally coordinated by only L4, whereas terminal zinc ions coordination sphere is completed by three water molecules. L4 exhibits a dual functionality of a bridging bidentate ligand as well as an anion. A dense hydrogen bonding network connects these trinuclear entity into a 3D supramolecular network. The ZnII ions in 6 are held at equidistance (3.848 Å) which coincidently matches with the corresponding Zn Zn distance in the binuclear zinc enzyme from Bacillus cereus (3.848 and 4.365 Å). Among L1–L5 screened for b-lactamase assay, L4 shows modest inhibition for BcII enzyme. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Peer Reviewed
See detailOptimal management of migraine taking into account comorbidities and “positive side effects”
Sándor, C; Dodick, DW; Schoenen, Jean ULg

in Schoenen, Jean; Dodick, DW; Sándor, C (Eds.) Comorbidity in Migraine (2011)

Detailed reference viewed: 7 (0 ULg)
See detailMicrobial Diversity and Processes in Lake Kivu (East Africa)
Llirós, M.; Darchambeau, François ULg; Garcia-Armisen, T. et al

Conference (2011)

Lake Kivu is a deep meromictic and oligotrophic tropical African lake with a permanent thermal- and haline stratification with huge accumulations of dissolved CO2 and CH4 (ca. 300 km3 and 60 km3 ... [more ▼]

Lake Kivu is a deep meromictic and oligotrophic tropical African lake with a permanent thermal- and haline stratification with huge accumulations of dissolved CO2 and CH4 (ca. 300 km3 and 60 km3, respectively) in the deep anoxic monimolimnion (from 60 o 480 m depth). Although there are a wealth of information on the ecology of small eukaryotes and their trophic role on Kivu, available information on prokaryotic planktonic assemblages is scarce. Molecular analysis of archaeal and bacterial communities showed a vertical segregation imposed by the permanent redoxcline. In relation to Bacteria, Actinobacteria, Betaproteobacteria, Green Sulfur Bacteria and Bacteroidetes were the most commonly retrieved groups. For Archaea, a marked dominance of Thaumarchaeota and Crenarchaeota (75% of all archaeal OTUs) over Euryarchaeota was observed. In the anoxic hypolimnion, Euryarchaoeta (Methanosarcinales and Methanocellales) lineages together with Miscellaneous Crenarchaeotic Group phylotypes were mainly recovered. In turn, Thaumarchaeota phylotypes were recovered in oxic and suboxic waters. CARDFISH analyses over the first 100 m revealed the dominance of Bacteria (51.4% – 95.7% of DAPI-stained cells), especially Actinobacteria (epilimnion), Betaproteobacteria (oxic-anoxic interface) and Bacteroidetes (upper hypolimnion), over Archaea (1.0% – 4.5%; maximum abundances at the oxic-anoxic interface). In turn, flow cytometry evidenced the dominance of HNA cells in the euphotic layer, whereas the proportion of LNA cells increased with depth. HNA and LNA populations were still observed in the anoxic hypolimnion suggesting facultative or strict anaerobic metabolisms. The detection of distinct depth maxima of nitrate, nitrite, archaeal amoA and Marine Thaumarchaeota 16S gene copy numbers together with regularly detection of deep maxima of 3H-Thymidine uptake, and the presence of low-light adapted GSB species point towards a strong link of N, C, and S cycles in the redoxcline of Lake Kivu. [less ▲]

Detailed reference viewed: 63 (2 ULg)