References of "2011"
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See detailMuscular forces affecting the outcome of CCL surgery.
Ramirez, L.; Böhme, Béatrice ULg; Vroomen, Carl ULg et al

in Proceedings of the 20th ECVS Congress (2011)

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See detailInfluence of the alveoli slopes on the discharge capacity of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Proceedings of the 34th IAHR world congress (2011)

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key ... [more ▼]

Piano Key Weir is a cost effective solution for rehabilitation as well as for new dam project with a high level of constraints (space, flood discharge, reservoir level).If the efficiency of the Piano Key Weir has already been well demonstrated, the definition of its optimal geometry has been still poorly approached. In order to improve the design of the complex geometry of this structure, the study of the influence of the mean geometrical parameters on the discharge capacity is an essential stage. Following a former experimental study of the flow over Piano Key Weirs, highlighting the mean influence of three geometrical parameters, this paper presents the results of an experimental parametric study. These results highlight the influence of the alveoli bottom slopes on the Piano Key Weir release capacity. Comparisons with numerical and analytical results, as well as design advices are also provided. [less ▲]

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See detailImprovement of the UNIQUAC combinatorial-entropy term by adjusting the standard segment
Bronneberg, Rob; Pfennig, Andreas ULg

in Journal of Chemical & Engineering Data (2011), 56

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See detailEffects of monopropanediamino-beta-cyclodextrin on the denaturation process of the hybrid protein BlaPChBD.
Vandevenne, Marylène ULg; GASPARD, Genevieve ULg; Belgsir, E. M. et al

in Biochimica et biophysica acta (2011)

Irreversible accumulation of protein aggregates represents an important problem both in vivo and in vitro. The aggregation of proteins is of critical importance in a wide variety of biomedical situations ... [more ▼]

Irreversible accumulation of protein aggregates represents an important problem both in vivo and in vitro. The aggregation of proteins is of critical importance in a wide variety of biomedical situations, ranging from diseases (such as Alzheimer's and Parkinson's diseases) to the production (e.g. inclusion bodies), stability, storage and delivery of protein drugs. beta-Cyclodextrin (beta-CD) is a circular heptasaccharide characterized by a hydrophilic exterior and a hydrophobic interior ring structure. In this research, we studied the effects of a chemically modified beta-CD (BCD07056), on the aggregating and refolding properties of BlaPChBD, a hybrid protein obtained by inserting the chitin binding domain of the human macrophage chitotriosidase into the class A beta-lactamase BlaP from Bacillus licheniformis 749/I during its thermal denaturation. The results show that BCD07056 strongly increases the refolding yield of BlaPChBD after thermal denaturation and constitutes an excellent additive to stabilize the protein over time at room temperature. Our data suggest that BCD07056 acts early in the denaturation process by preventing the formation of an intermediate which leads to an aggregated state. Finally, the role of beta-CD derivatives on the stability of proteins is discussed. [less ▲]

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See detailSubtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.
Rizzoli, R.; Akesson, K.; Bouxsein, M. et al

in Osteoporosis International (2011), 22

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this ... [more ▼]

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this association, but retrospective phase III trial analyses show no increased risk. Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is yet unproven. INTRODUCTION: A Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the International Osteoporosis Foundation has reviewed the evidence for a causal association between subtrochanteric fractures and long-term treatment with bisphosphonates, with the aim of identifying areas for further research and providing recommendations for physicians. METHODS: A PubMed search of literature from 1994 to May 2010 was performed using key search terms, and articles pertinent to subtrochanteric fractures following bisphosphonate use were analysed. RESULTS: Several clinical case reports and case reviews report a possible association between atypical fractures at the subtrochanteric region of the femur in bisphosphonate-treated patients. Common features of these 'atypical' fractures include prodromal pain, occurrence with minimal/no trauma, a thickened diaphyseal cortex and transverse fracture pattern. Some small case-control studies report the same association, but a large register-based study and retrospective analyses of phase III trials of bisphosphonates do not show an increased risk of subtrochanteric fractures with bisphosphonate use. The number of atypical subtrochanteric fractures in association with bisphosphonates is an estimated one per 1,000 per year. It is recommended that physicians remain vigilant in assessing their patients treated with bisphosphonates for the treatment or prevention of osteoporosis and advise patients of the potential risks. CONCLUSIONS: Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is unproven and requires further research. Were the case to be proven, the risk-benefit ratio still remains favourable for use of bisphosphonates to prevent fractures. [less ▲]

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See detailcompte rendu de : S. Douglas OLSON (Ed.), Athenaeus. The Learned Banqueters. Books 12-13.594b
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2011), 80

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See detailSimulations numériques de figures de diffractions à l'usage de la sixième secondaire et du premier baccalauréat
Leblanc, Christophe ULg

in Bulletin de l'Association Belge des Professeurs de Physique et de Chimie [Bulletins de l'ABPPC] (2011), 49(190),

La diffraction constitue de nos jours un phénomène physique incontournable pour la recherche (diffraction par rayons X, diffraction de neutrons, cristallographie, ...) et est, à juste titre, enseignée ... [more ▼]

La diffraction constitue de nos jours un phénomène physique incontournable pour la recherche (diffraction par rayons X, diffraction de neutrons, cristallographie, ...) et est, à juste titre, enseignée aussi bien en dernière année de secondaire qu'à l'université. Le logiciel présenté ci-dessous est un programme permettant de réaliser des figures de diffractions de manière simple et intuitive. Il existe naturellement déjà de nombreux programmes de simulations de figures de diffractions que l'on peut facilement trouver sur internet. Cependant ceux-ci sont, pour la plupart, ou bien limités (à la connaissance de l'auteur) à quelques cas particuliers - diffractions sur une ou plusieurs fentes, un rond, plus rarement un carré - ou bien complexes à l'utilisation. Bien que ces programmes soient dignes d'intérêts et peuvent se montrer utiles dans le cadre d'un enseignement, leurs limitations empêchent d'acquérir une intuition réelle de ce qu'est la diffraction. Par exemple, quelle est la figure de diffraction obtenue par un réseau cristallin cubique, un réseau hexagonal, ou encore une hélice ? C'est précisément cette faille pédagogique que vient combler le logiciel présenté ci-dessous. En effet, celui-ci permet d'obtenir la figure de diffraction de « n'importe quelle forme » (en deux dimensions), « forme » entièrement paramétrable par l'utilisateur au moyen d'un simple fichier bitmap ; format de fichier graphique le plus répandu et le plus simple à employer. Il est naturellement également possible d'effectuer de la diffraction de manière expérimentale au moyen d'un simple laser hélium-néon (facilement accessible dans le commerce et d'un prix modéré) et de diapositives. Cependant, outre que le logiciel présenté ci-dessous peut-être obtenu gratuitement par simple demande à l'auteur, celui-ci se montre beaucoup plus souple d'utilisation que de simples diapositives car entièrement paramétrable, et, comme tout logiciel, échappe aux aléas expérimentaux (poussières sur les diapositives, problèmes d'alignements diapositives-laser, nécessité d'un local sombre, ...) [less ▲]

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See detailThe Producerist Narrative in Right-wing Flanders
Jamin, Jérôme ULg

Conference (2011)

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See detailDescription of the bone-remodeling pattern after socket preservation procedures in human: a methodological study
LAMBERT, France ULg; VINCENT, Kim ULg; VANHOUTTE, Vanessa ULg et al

Poster (2011)

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review ... [more ▼]

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review. Multiple surgical protocols using biomaterials are proposed in order to limit the typical postextraction bone resorption. However, because of the heterogeneity of the studies and, more specifically, of the assessment methods, it is difficult to assert the superiority of one technique over another. Aim: The objective of this study was to develop a new radiographic method to assess alveolar bone remodeling after socket preservation procedures. Methods: Sixteen extraction sites (in 14 patients) localized in the upper anterior maxilla were treated with bovine hydroxyapatite (0.25–1mm particles) and a saddled connective tissue graft. A radiographic 3-dimensional assessment of the hard tissues was performed at baseline and at 3 months after the procedure. Standardized horizontal measurements were taken at three corono apical levels ( 2, 5, and 9mm) and at three mesio-diatal level (Mesial, Center, and Distal) in the buccal and palatal aspects. Vertical measurements were also recorded in nine regions over the top of the alveolar crest. Results: Extraction socket-preservation technique assessed in the present study significantly reduced horizontal bone remodeling. The horizontal dimension of the crest decreased by 1.6mm (20%) in the cervical regions ( 2mm level), experienced a moderate decrease of 1mm (12%) at the 5mm level, and experienced a very low decrease of 0.5mm(6%) in the apical ( 8mm) level. The losses were always significantly higher in the buccal than in the palatal aspect. Buccally, the maximal bone remodeling at the cervical level remained below 1mm. Vertical bone resorption was homogeneous and was < 1mm in the nine measured regions. Conclusions and clinical implications: The radiographic measuring methodology proved to be accurate and reproducible. It can be applied in other clinical settings. Moreover, the surgical procedure evaluated in the present study, significantly limits the postextraction buccal bone remodeling compared with the data found in the literature for untreated extraction socket in the aesthetic area. However, a complete inhibition of the bone remodeling was not reached and the authors suggest a surgical technique using a ‘‘saddled’’ connective tissue graft to thicken buccal soft tissue biotype and consequently compensate for cervical bone loss. [less ▲]

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See detailLes options législatives prises par la Belgique, la France et le Luxembourg à l'occasion de la transposition de la directive "fusions transfrontalières"
Corbisier, Isabelle ULg

in Fusions transfrontalières de sociétés. Droit luxembourgeois et droit comparé. (2011)

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See detailBenthic remineralization in the northwest European continental margin (northern Bay of Biscay)
Suykens, Kim; Schmidt, Sabine; Delille, Bruno ULg et al

in Continental Shelf Research (2011), 31

We report a dataset of sediment characteristics and biogeochemical fluxes at the watersediment interface at the northwest European continental margin (northern Bay of Biscay). Cores were obtained in June ... [more ▼]

We report a dataset of sediment characteristics and biogeochemical fluxes at the watersediment interface at the northwest European continental margin (northern Bay of Biscay). Cores were obtained in June 2006, May 2007 and 2008, at 18 stations on the shelf break (120 to 180 m), and at 2 stations on the continental slope (520 m and 680 m). Water-sediment fluxes of dissolved oxygen (O2), total alkalinity (TA), nitrate (NO3-), and dissolved silicate (DSi) were measured at a total of 20 stations. Sediment characteristics include: grain size, chlorophyll-a (Chl-a) and phaeopigment (Phaeo) content, particulate organic (POC) and inorganic (PIC) carbon content, and lead-210 (210Pb) and thorium-234 (234Th) activities. Sediments were sandy (fine to coarse) with organic matter (OM) (1.0 - 4.0 %) and Chl-a (0.01 - 0.95 μg g-1) contents comparable to previous investigations in the same region, and a relatively high PIC fraction (0.8 - 10.2 %). Water-sediment O2 fluxes (-2.4 to -8.4 mmol O2 m-2 d-1) were low compared to other coastal environments and correlated well with OM and Chl-a content. 234Th activity profiles indicated that Chl-a sediment content was mainly controlled by physical mixing processes related to local hydrodynamics. The correlation between water-sediment fluxes of O2 and NO3- indicated a close coupling of nitrification/denitrification and total benthic organic carbon degradation. Dissolution of biogenic silica (0.05 to 0.95 mmol m-2 d-1) seemed uncoupled from organic carbon degradation, as characterized by water-sediment O2 fluxes. The link between water-sediment fluxes of TA and O2 indicated the occurrence of metabolic driven dissolution of calcium carbonates (CaCO3) in the sediments (~ 0.33 ± 0.47 mmol m-2 d-1) which represented ~ 1 % of the pelagic calcification rates due to coccolithophores measured during the cruises. These CaCO3 dissolution rates were below those reported in sediments of continental slopes and of the deep ocean, probably due to the high over-saturation with respect to CaCO3 of the water column overlying the continental shelf sediments of the northern Bay of Biscay. Rates of total benthic organic carbon degradation were low compared to water column rates of primary production and aphotic community respiration obtained during the cruises. [less ▲]

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See detailTraumatologie du basketball
Kaux, Jean-François ULg; Crielaard, Jean-Michel ULg

Learning material (2011)

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See detailCompetitive facility location problem with attractiveness adjustment of the follower: A bilevel programming model and its solution
Kucukaydin, Hande ULg; Aras, Necati; Altinel, I. Kuban

in European Journal of Operational Research (2011), 208(3), 206-220

We are concerned with a problem in which a firm or franchise enters a market by locating new facilities where there are existing facilities belonging to a competitor. The firm aims at finding the location ... [more ▼]

We are concerned with a problem in which a firm or franchise enters a market by locating new facilities where there are existing facilities belonging to a competitor. The firm aims at finding the location and attractiveness of each facility to be opened so as to maximize its profit. The competitor, on the other hand, can react by adjusting the attractiveness of its existing facilities with the objective of maximizing its own profit. The demand is assumed to be aggregated at certain points in the plane and the facilities of the firm can be located at predetermined candidate sites. We employ Huff's gravity-based rule in modeling the behavior of the customers where the fraction of customers at a demand point that visit a certain facility is proportional to the facility attractiveness and inversely proportional to the distance between the facility site and demand point. We formulate a bilevel mixed-integer nonlinear programming model where the firm entering the market is the leader and the competitor is the follower. In order to find the optimal solution of this model, we convert it into an equivalent one-level mixed-integer nonlinear program so that it can be solved by global optimization methods. Apart from reporting computational results obtained on a set of randomly generated instances, we also compute the benefit the leader firm derives from anticipating the competitor's reaction of adjusting the attractiveness levels of its facilities. The results on the test instances indicate that the benefit is 58.33% on the average. [less ▲]

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See detailCoordination of verbal dependents in Old French : Coordination as a specified juxtaposition or apposition
Mazziotta, Nicolas ULg

in Gerdes, Kim; Hajičova, Eva; Wanner, Leo (Eds.) Proceedings of Depling 2011, International Conference on Dependency Linguistics, Barcelona (2011)

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See detail1D numerical modeling of the flow over a Piano Key Weir
Erpicum, Sébastien ULg; Machiels, Olivier ULg; Archambeau, Pierre ULg et al

in Erpicum, Sébastien; Laugier, Frédéric; Boillat, Jean Louis (Eds.) et al Labyrinth and Piano Key Weirs - PKW 2011 (2011)

Because of the PK-Weir geometric specificities, its hydraulic capacity remains difficult to predict without using experimental techniques. A 1D numerical model of the flow over a PK-Weir has been ... [more ▼]

Because of the PK-Weir geometric specificities, its hydraulic capacity remains difficult to predict without using experimental techniques. A 1D numerical model of the flow over a PK-Weir has been developed at the Research unit HACH at the University of Liege. It is based on a 1D modeling of the inlet and the outlet separately, with a single upstream reservoir and interactions between both flows by exchange of mass and momentum along the lateral crest. The comparison of the numerical results with various experimental data showed the ability of the numerical model to predict with reasonable accuracy the release capacity of a PK-Weir, whatever its geometry. The tests of the solver enable to highlight the significant influence of the inlet and outlet width on the weir release capacity. They also suggest that improvements of the numerical model may lie in the evaluation of the discharge coefficient of the lateral crest. [less ▲]

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See detailZinc complexes with 1,2,4-triazole functionalized amino acid derivatives: Synthesis, structure and b-lactamase assay
Naik, Anil; Beck, Joséphine; Dîrtu, Marinela et al

in Inorganica Chimica Acta (2011), 368

Coordinating abilities of 4R-1,2,4-triazole derivatives (R = glycine ethyl ester (L1), glycine (L2), diethylamino malonate (L3), methionine (L4) and diethyl aminomethylphosphonate (L5)) towards ZnII ions ... [more ▼]

Coordinating abilities of 4R-1,2,4-triazole derivatives (R = glycine ethyl ester (L1), glycine (L2), diethylamino malonate (L3), methionine (L4) and diethyl aminomethylphosphonate (L5)) towards ZnII ions have been studied in solution, in solid state and versus three zinc-b-lactamases. The crystal structure of [Zn3(L4)6(H2O)6] (6) is described; it is the first crystal structure involving a 1,2,4-triazole functionalized methionine. It forms a trinuclear complex with central zinc octahedrally coordinated by only L4, whereas terminal zinc ions coordination sphere is completed by three water molecules. L4 exhibits a dual functionality of a bridging bidentate ligand as well as an anion. A dense hydrogen bonding network connects these trinuclear entity into a 3D supramolecular network. The ZnII ions in 6 are held at equidistance (3.848 Å) which coincidently matches with the corresponding Zn Zn distance in the binuclear zinc enzyme from Bacillus cereus (3.848 and 4.365 Å). Among L1–L5 screened for b-lactamase assay, L4 shows modest inhibition for BcII enzyme. [less ▲]

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See detailLarge carrion beetles (Coleoptera, Silphidae) in Western Europe: a review
Dekeirsschieter, Jessica ULg; Verheggen, François ULg; Lognay, Georges ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2011), 15(3), 425-437

This review focuses on carrion beetles (Coleoptera, Silphidae) of the Western Palearctic and their potential use in forensic entomology as bioindicators. Few studies have looked at Silphidae in forensic ... [more ▼]

This review focuses on carrion beetles (Coleoptera, Silphidae) of the Western Palearctic and their potential use in forensic entomology as bioindicators. Few studies have looked at Silphidae in forensic context and investigations. However, some Silphidae present the desirable characteristics of some Diptera used in postmortem estimates and thus may extend the minimum postmortem interval (PMImin). We review here the taxonomy and distribution of Western Palearctic Silphidae. The anatomical and morphological characteristics of both subfamilies are described for adults and larvae. The biology and ecology of silphids are also summarized for Silphinae and Nicrophorinae. A specific chapter gives an overview of the current uses of Silphidae in forensic entomology as postmortem indicator. [less ▲]

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See detailIdentifying the default-mode component in spatial IC analyses of patients with disorders of consciousness.
Soddu, Andrea ULg; Vanhaudenhuyse, Audrey ULg; Bahri, Mohamed Ali ULg et al

in Human Brain Mapping (2011)

Objectives:Recent fMRI studies have shown that it is possible to reliably identify the default-mode network (DMN) in the absence of any task, by resting-state connectivity analyses in healthy volunteers ... [more ▼]

Objectives:Recent fMRI studies have shown that it is possible to reliably identify the default-mode network (DMN) in the absence of any task, by resting-state connectivity analyses in healthy volunteers. We here aimed to identify the DMN in the challenging patient population of disorders of consciousness encountered following coma. Experimental design: A spatial independent component analysis-based methodology permitted DMN assessment, decomposing connectivity in all its different sources either neuronal or artifactual. Three different selection criteria were introduced assessing anticorrelation-corrected connectivity with or without an automatic masking procedure and calculating connectivity scores encompassing both spatial and temporal properties. These three methods were validated on 10 healthy controls and applied to an independent group of 8 healthy controls and 11 severely brain-damaged patients [locked-in syndrome (n = 2), minimally conscious (n = 1), and vegetative state (n = 8)]. Principal observations: All vegetative patients showed fewer connections in the default-mode areas, when compared with controls, contrary to locked-in patients who showed near-normal connectivity. In the minimally conscious-state patient, only the two selection criteria considering both spatial and temporal properties were able to identify an intact right lateralized BOLD connectivity pattern, and metabolic PET data suggested its neuronal origin. Conclusions: When assessing resting-state connectivity in patients with disorders of consciousness, it is important to use a methodology excluding non-neuronal contributions caused by head motion, respiration, and heart rate artifacts encountered in all studied patients. Hum Brain Mapp, 2011. (c) 2011 Wiley-Liss, Inc. [less ▲]

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See detailOptimal linear taxation under endogenous longevity
Pestieau, Pierre ULg; Leroux, ML; Ponthiere, Gregory

in Journal of Population Economics (2011), 24

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See detailAntibody production by injection of living cells expressing non self antigens as cell surface type II transmembrane fusion protein.
Nizet, Yannick; Gillet, Laurent ULg; SCHROEDER, Hélène ULg et al

in Journal of immunological methods (2011)

Antigen expression and purification are laborious, time consuming and frequently difficult steps in the process of antibody production. In the present study, we developed a method avoiding these two steps ... [more ▼]

Antigen expression and purification are laborious, time consuming and frequently difficult steps in the process of antibody production. In the present study, we developed a method avoiding these two steps. This method relies on the injection of histocompatible living cells stably expressing the antigen as a cell surface type II transmembrane fusion protein. A vector, nicknamed pCD1-CD134L, was constructed to express the antigen fused at the carboxyterminal end of the human CD134 ligand (CD134L) type II transmembrane protein on the surface of eucaryotic cells. This vector was shown to induce cell surface expression of epitopes from human c-Myc (soluble protein), uterogloblin-related protein 1 (secreted protein) and CD94 (type II transmembrane protein). Using this vector, we developed a method to produce antibodies without antigen production. The flowchart of this method is as follows: (i) cloning of the antigen in the pCD1-CD134L vector; (ii) production of a histocompatible cell line stably expressing the CD134L-antigen fusion protein; (iii) testing for cell surface expression of the fusion protein by targeting the CD134L carrier; and (iv) prime-boost immunisation with living cells expressing the fusion protein. This method was successfully used for production of polyclonal antibodies raised against Ixodes ricinus calreticulin (secreted protein) in mice and for production of monoclonal antibodies raised against an epitope of Vaccinia virus A56 (type I transmembrane protein) protein in rat. The present study is the first to demonstrate the use of a type II transmembrane protein as a carrier for cell surface display of antigens. [less ▲]

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