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See detailComment arriver à la prothèse pénienne
Andrianne, Robert ULg

Scientific conference (2011)

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See detailSentiment d’altérité dans la correspondance de Rousseau en 1762
Biquet, Stéphanie ULg

in Turekova, Andrea (Ed.) Conférence internationale Autre - Autrui - Altérité (2011)

Jean-Jacques Rousseau est né avec la conscience de son altérité : fils d’horloger, citoyen de Genève, il se sent dès son plus jeune âge différent du monde qui l’entoure. Par sa « réforme » au début des ... [more ▼]

Jean-Jacques Rousseau est né avec la conscience de son altérité : fils d’horloger, citoyen de Genève, il se sent dès son plus jeune âge différent du monde qui l’entoure. Par sa « réforme » au début des années 1750, il transformera officiellement cette altérité en faire-valoir. Pourtant, quand résonne le glas de la condamnation de ses œuvres (Émile et le Contrat social) en 1762, l’homme jusque-là différent, se sent étranger, incompris, seul contre tous, comme en témoigne sa correspondance. Cet article se donne pour objectif d’étudier ce sentiment d’altérité et d’étrangeté à travers la correspondance personnelle de Jean-Jacques Rousseau de 1762 à 1765 (soit de la condamnation de l’Émile et du Contrat social jusqu'au départ pour l’Angleterre chez David Hume). [less ▲]

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See detailQuality assurance in repairing industrial floors: parameters and recommendations
Courard, Luc ULg; Bissonnette, Benoît

in Zajc, A.; Sustercic, J. (Eds.) Moznot Pocenitive Izvajanja Betonarskih Del (2011)

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete ... [more ▼]

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete structures is constantly increasing, and therefore repair or retrofitting requirements increase. Present concerns of sustainable development emphasizing repair or strengthening instead of new construction, acts as incentive to this trend. The bonded overlay technique is particularly suitable in the case of structures with large areas like industrial floors. This paper has the ambition to present reliable design methodology for the practitioner. Surface preparation, overlay design and material selection, application process and QC/QA are discussed and guidelines are proposed in order to enhance quality of repair operations. [less ▲]

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See detailLe modèle de croissance katangais face à la crise financière mondiale : enjeux en termes d'emploi
Lapeyre, Frédéric; Lebailly, Philippe ULg; Musewa M'Bayo, Laki et al

Book published by Bureau International du Travail (2011)

La crise financière mondiale qui a éclaté en 2008 et les effets désastreux qu’elle a occasionnés sur le secteur minier en RDC (qui avait été placé au centre des politiques de croissance et de lutte contre ... [more ▼]

La crise financière mondiale qui a éclaté en 2008 et les effets désastreux qu’elle a occasionnés sur le secteur minier en RDC (qui avait été placé au centre des politiques de croissance et de lutte contre la pauvreté) posent avec encore plus d’acuité la question de la diversification de la structure économique dans une province comme le Katanga. Au problème de la vulnérabilité d’un tel modèle de croissance s’ajoute le constat qui est fait dans cette étude du manque d’effet d’entrainement de l’activité des grands groupes miniers sur le reste de l’économie locale, en termes de développement des capacités productives et de création d’emplois. [less ▲]

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See detailPhysico-chemical mechanisms affecting the adherence of starch granules on materials with different hydrophobicities
Detry, Jean; Sindic, Marianne ULg; Servais, Marjorie et al

in Journal of Colloid & Interface Science (2011), 355

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See detailSubclinical diseases underlying poor performance in endurance horses: diagnostic methods and predictive tests.
Fraipont, Audrey ULg; Van Erck, E.; Ramery, Eve ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2011), 169(6), 154

Thirty-eight endurance horses underwent clinical and ancillary examinations, including haematological and biochemical evaluation, standardised exercise tests both on a treadmill and in the field, Doppler ... [more ▼]

Thirty-eight endurance horses underwent clinical and ancillary examinations, including haematological and biochemical evaluation, standardised exercise tests both on a treadmill and in the field, Doppler echocardiography, impulse oscillometry, video endoscopy and collection of respiratory fluids. All of the examined poorly performing horses were affected by subclinical diseases, and most of them had multiple concomitant disorders. On the contrary, the well-performing horses were free of any subclinical disease. The most frequently diagnosed diseases were respiratory disorders, followed by musculoskeletal and cardiac problems. Poor performers exhibited lower speeds at blood lactate concentration of 4 mmol/l (VLA4) and at heart rates of 160 (V160) and 200 bpm (V200) on the treadmill and in the field, as well as slower recovery of heart rate. [less ▲]

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See detailMéthode pragmatique d’évaluation de la réserve en eau des stations forestières et cartographie à l’échelle régionale (Wallonie, Belgique)
Ridremont, François ULg; Lejeune, Philippe ULg; Claessens, Hugues ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2011), 15(S2), 727-741

The assessment of the forest sites water availability constitutes a growing concern following the awareness of the potential impact of climate change on the soil moisture regime. At the present time, the ... [more ▼]

The assessment of the forest sites water availability constitutes a growing concern following the awareness of the potential impact of climate change on the soil moisture regime. At the present time, the forest managers lack tools for a quantitative estimation of the soil water reserve. This paper presents a simple estimation method that can be adopted on field by foresters. A map of this soil water reserve at the forest site scale has been established for the Southern Belgium. After the inventory of the possible techniques, the “textural method”, based on the pedotransfert classes of Jamagne et al. (1977), has been used. The soil profiles from the Aardewerk database have eased the translation of the Jamagne et al. (1977)’s results in the Belgian textural system. Moreover, the geodatabase of the Digital Soil Map of Wallonia (DSMW), through the typology of the major soil types, has been used as mapping support of the water reserve at the regional scale. Like a first attempt of validation, the result has been compared with the bioindicator character of forest understory vegetation. The regression results show a significant relationship between the soil water reserve and the vegetation estimate, but they also indicate that the water reserve does not explain alone the moisture level expressed by the flora. It emerges that the characterization of the Walloon parent materials will constitute an undeniable support for the development of the proposed method, the transposition of foreign results leading to some bias. The use prospects of this thematic map are multiple: integration as inputs for the autecological modelling, assessment of the moisture regime for the water availability of forest sites and building of sites catalogs; as many tools to guide forest managers in their planning measures. [less ▲]

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See detailPour une épistémologie des Lettres
Badir, Sémir ULg

in Fabula LHT (2011), 8

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See detailPhysico-chemical and morphological properties of current particulated biomaterials used in alveolar bone augmentations: a review.
LAMBERT, France ULg; Layrolle, Pierre; ROMPEN, Eric ULg et al

in Journal of Osteology and Biomaterials (2011), 2

The efficacy of grafting materials for alveolar bone regeneration procedures has been repeatedly corroborated by clinical and scientific evidence. Although an ever growing number of biomaterials are ... [more ▼]

The efficacy of grafting materials for alveolar bone regeneration procedures has been repeatedly corroborated by clinical and scientific evidence. Although an ever growing number of biomaterials are available on the market, the origins, material characteristics, bioactivity and osteoconductive properties of these products are not always known by clinicians, hence often hampering an adequate product selection. The purpose of this contribution was to provide an overview of five different types of osteoconductive grafting materials frequently used in dentistry (Bio-Oss®, Cerasorb M™, Bone Ceramic®, Natix®, Genos®) and to summarize their physico-chemical and morphological characteristics at the macro- and micro-scale. Furthermore, the influence of these properties on the in vivo behaviour of these biomaterials is discussed. The results of this study are presented as data sheets, which may prove helpful for clinicians in the design of their treatment strategies. [less ▲]

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See detailSeasonal variations in vitamin D levels in melanoma patients : a single-centre prospective pilot comparative study
FAILLA, Valérie ULg; CAVALIER, Etienne ULg; EL HAYDERI, Lara ULg et al

in Journal of the European Academy of Dermatology & Venereology (2011)

Background: More than 90% of vitamin D synthesis is dependent on UV exposure. Photosensitive disorders such as lupus erythematosus, protoporphyria and xeroderma require strict sun avoidance, and vitamin D ... [more ▼]

Background: More than 90% of vitamin D synthesis is dependent on UV exposure. Photosensitive disorders such as lupus erythematosus, protoporphyria and xeroderma require strict sun avoidance, and vitamin D deficiency has been demonstrated in these patients. Melanoma patients are also instructed to avoid sun exposure and may hence be expected to be vitamin D deficient. Materials and method : Winter and summer vitamin D levels were compared in a group of melanoma patients (n=61) and age- and phototype-matched controls (n=53) without photosensitive disorders. Results : Oral supplementary vitamin D intake was reported in 32.7% of the melanoma patients and in 15.1 % in the control group. Despite oral supplementation, only 25% of the melanoma patients and the controls presented with vitamin D levels of 30 ng/mL or higher. In non-supplemented subjects in the melanoma and control groups, respectively, mean winter vitamin D levels were below the recommended threshold at 12,6 ng/mL vs 13.2 ng/mL, respectively, but not statistically different. These values increased significantly in both groups during the summer to 24.6 and 23.8 ng/mL respectively. Conclusion: Unexpected, significant increases in vitamin D levels were seen in melanoma patients during summer, suggesting non-adherence with photoprotective measures and reflecting a heliophilic behaviour. Vitamin D supplementation is recommended in melanoma patients during both winter and summer. [less ▲]

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See detailTropfenpopulationsbilanzen zur Auslegung von Extraktionskolonnen
Adinata, Donni; Ayesteran, José M.; Buchbender, Florian et al

in Chemie Ingenieur Technik (2011), 83(7), 952964

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See detailLes Codes La Charte. Droit international conventionnel et Droit administratif
Bourgeois, Marc ULg; Behrendt, Christian ULg; Lewalle, Paul ULg et al

Book published by La Charte (2011)

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See detailReciprocal interactions between wakefulness and sleep influence global and regional brain activity
Muto, Vincenzo ULg; Mascetti, Laura ULg; Matarazzo, Luca et al

in Current Topics in Medicinal Chemistry (2011), 11(19), 2403-13

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See detailSequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.
Moens, Lotte N.; De Rijk, Peter; Reumers, Joke et al

in PloS one (2011), 6(8), 23450

In recent years, DISC1 has emerged as one of the most credible and best supported candidate genes for schizophrenia and related neuropsychiatric disorders. Furthermore, increasing evidence--both genetic ... [more ▼]

In recent years, DISC1 has emerged as one of the most credible and best supported candidate genes for schizophrenia and related neuropsychiatric disorders. Furthermore, increasing evidence--both genetic and functional--indicates that many of its protein interaction partners are also involved in the development of these diseases. In this study, we applied a pooled sample 454 sequencing strategy, to explore the contribution of genetic variation in DISC1 and 10 of its interaction partners (ATF5, Grb2, FEZ1, LIS-1, PDE4B, NDE1, NDEL1, TRAF3IP1, YWHAE, and ZNF365) to schizophrenia susceptibility in an isolated northern Swedish population. Mutation burden analysis of the identified variants in a population of 486 SZ patients and 514 control individuals, revealed that non-synonymous rare variants with a MAF<0.01 were significantly more present in patients compared to controls (8.64% versus 4.7%, P = 0.018), providing further evidence for the involvement of DISC1 and some of its interaction partners in psychiatric disorders. This increased burden of rare missense variants was even more striking in a subgroup of early onset patients (12.9% versus 4.7%, P = 0.0004), highlighting the importance of studying subgroups of patients and identifying endophenotypes. Upon investigation of the potential functional effects associated with the identified missense variants, we found that approximately 90% of these variants reside in intrinsically disordered protein regions. The observed increase in mutation burden in patients provides further support for the role of the DISC1 pathway in schizophrenia. Furthermore, this study presents the first evidence supporting the involvement of mutations within intrinsically disordered protein regions in the pathogenesis of psychiatric disorders. As many important biological functions depend directly on the disordered state, alteration of this disorder in key pathways may represent an intriguing new disease mechanism for schizophrenia and related neuropsychiatric diseases. Further research into this unexplored domain will be required to elucidate the role of the identified variants in schizophrenia etiology. [less ▲]

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See detailMitotic spindle: focus on the function of huntingtin
Godin, Juliette ULg; Humbert, Sandrine

in International Journal of Biochemistry & Cell Biology (2011), 43(6), 852-856

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See detailBrain perfusion patterns in familial frontotemporal lobar degeneration.
Seelaar, H.; Papma, J. M.; Garraux, Gaëtan ULg et al

in Neurology (2011), 77(4), 384-92

OBJECTIVE: Frontotemporal lobar degeneration (FTLD) is a clinically, genetically, and pathologically heterogeneous disorder. The aim of this study was to compare clinical features and perfusion patterns ... [more ▼]

OBJECTIVE: Frontotemporal lobar degeneration (FTLD) is a clinically, genetically, and pathologically heterogeneous disorder. The aim of this study was to compare clinical features and perfusion patterns on SPECT of patients with familial FTLD-TAR DNA binding protein 43 kDa (TDP) and MAPT mutations. METHODS: Patients were included if they had MAPT or GRN mutations, positive family history with pathologically proven FTLD in the patient or first-degree relative, or were part of FTD-MND families. All patients and 10 age- and gender-matched controls underwent measurement of brain perfusion using (99m)Tc-HMPAO SPECT. We used SPM8 to perform image processing and voxel-based group analyses (p < 0.001). Gender and age were included as nuisance variables in the design matrices. RESULTS: Of the 29 patients with familial FTLD, 19 had familial FTLD-TDP (GRN mutations in 6), and 10 had MAPT mutations. At clinical presentation, familial FTLD-TDP patients were older at onset (p = 0.030) and had more memory deficits (p = 0.011), whereas patients with MAPT had more naming deficits (p < 0.001) and obsessive-compulsive behavior (p = 0.001). The between-groups SPECT analyses revealed significantly less perfusion in the right frontal lobe, precuneus, cuneus, and inferior parietal lobule in familial FTLD-TDP, whereas significantly less perfusion was found in the left temporal and inferior frontal gyri in MAPT. Post hoc analysis of familial FTLD-TDP with unknown genetic defect vs MAPT revealed less perfusion in the right frontal and parietal lobe. CONCLUSION: Familial FTLD-TDP shows relatively more posterior hypoperfusion, including the precuneus and inferior parietal lobule, possibly related to significant memory impairment. Patients with MAPT were characterized by impaired perfusion of the temporal regions and naming deficits. [less ▲]

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See detailFlow cytometric detection of myeloperoxidase in horse neutrophils: a novel technique in equine diagnostic research.
Wauters, Jella; Franck, Thierry ULg; Pille, Frederik et al

in Veterinary Immunology and Immunopathology (2011), 144(3-4), 417-22

Myeloperoxidase (MPO) is a protein of interest due to its involvement in equine pathologies. Until now, results in equine diagnostic research were achieved through extracellular MPO detection. However ... [more ▼]

Myeloperoxidase (MPO) is a protein of interest due to its involvement in equine pathologies. Until now, results in equine diagnostic research were achieved through extracellular MPO detection. However, studying the cellular MPO content in neutrophils has revealed important insights in human diseases. This study aimed to develop a technique for the specific detection of MPO on the single cell level defining a flow cytometric protocol for the detection of both equine surface-bound and cellular MPO. Both indirect and direct labeling techniques are described which include the comparison of two secondary antibodies and two linking-fluorochromes, respectively. [less ▲]

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See detailShort Course Froth Flotation - Part III: PGEs ores
Bastin, David ULg

Learning material (2011)

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