References of "2011"
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See detailMultiscale modeling of sprouting angiogenesis
Carlier, Aurélie ULg; Geris, Liesbet ULg; Van Oosterwyck, Hans

Poster (2011, December 02)

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See detailParameter Identification in a Model of the Cardiovascular System Including the Atria
Pironet, Antoine ULg; Revie, James A.; Paeme, Sabine ULg et al

Poster (2011, December 02)

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See detailEffects of temperature on pacemaker activity induced by mechano-electric feedback in a one-dimensional model of a ring-shaped cardiac fiber
Collet, Arnaud ULg; Desaive, Thomas ULg; Dauby, Pierre ULg

in NCBME (Ed.) 10th Belgian Day on Biomedical Engineering (2011, December 02)

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See detailDystocies équines: Données descriptives et approche de la gestion des soins intensifs
Deleuze, Stefan ULg; de la Rebière de Pouyade, Geoffroy ULg; Sandersen, Charlotte ULg et al

Conference (2011, December 02)

La fréquence de fourbures rencontrées après une dystocie semble faible par rapport à la littérature. L’ajout d’héparines fractionnées aux traitements habituels de la métrite du post-partum (ocytocine ... [more ▼]

La fréquence de fourbures rencontrées après une dystocie semble faible par rapport à la littérature. L’ajout d’héparines fractionnées aux traitements habituels de la métrite du post-partum (ocytocine, lavage utérins, antibiotiques et anti-inflammatoires) semble intéressant pour réduire le risque de fourbure. [less ▲]

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See detailLes innombrables formes des Mille et une Nuits : quelques éditions, traditions, traductions... et trahisons
Franssen, Elise ULg

Conference (2011, December 02)

Dans le domaine des études arabes, de nombreux textes attendent encore d’être édités. D’autres l’ont été par le passé, mais ne répondent pas aux principes de l’édition critique moderne. C’est notamment le ... [more ▼]

Dans le domaine des études arabes, de nombreux textes attendent encore d’être édités. D’autres l’ont été par le passé, mais ne répondent pas aux principes de l’édition critique moderne. C’est notamment le cas des Mille et une Nuits. [less ▲]

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See detailNESCAV - Premiers résultats
Streel, Sylvie ULg; Donneau, Anne-Françoise ULg; Hoge, Axelle ULg et al

Conference (2011, December 02)

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See detailEcological characterization of Lophira alata (Ekki), a vulnerable timber tree species, in order to develop silvicultural effective strategies
Biwole, Achille ULg; Doucet, Jean-Louis ULg

Poster (2011, December 02)

Ekki, Lophira alata Banks ex C.F.Gaertn., is an African timber species occurring in tropical rainforests. Of important commercial value, this species is logged for its excellent timber properties and has ... [more ▼]

Ekki, Lophira alata Banks ex C.F.Gaertn., is an African timber species occurring in tropical rainforests. Of important commercial value, this species is logged for its excellent timber properties and has been classified by the IUCN as «vulnerable" species. As for many other tropical tree species, the commercial exploitation of Ekki is confronted to an insufficient knowledge about the species’ ecological profile. With a distribution range limited to the Guinea-Congolian region, Ekki often displays insufficient natural regeneration, but the biotic and abiotic factors explaining this deficiency have been hardly characterized. This lack of knowledge makes it difficult to model the population dynamics on the long term. The reproductive biology of Ekki and the genetic variability of its population remains poorly studied too. To address this situation, a fundamental and applied research is being undertaken in the forest concessions managed by Wijma Cameroun SA., covering over 250,000 hectares of rainforest in Southern Cameroon. This study aims to answer four essential questions: (1) what is the phylogenetic relationship between L. alata and L. lanceolata, (2) how paleoclimate and human disturbances impact its distribution and abundance, (3) how to these populations respond to logging over several rotation periods, (4) does logging promote or inhibit the natural regeneration of the species. Several study devices have thus been installed to collect the data needed to improve the characterization of Ekki’s ecology and to conceive silvicultural strategies. [less ▲]

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See detailVitamin D measurement: Laboratory issues
CAVALIER, Etienne ULg

Conference (2011, December 02)

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See detailThe Solar Sail Materials (SSM) project – Status of activities
Della Vedova, Florio; Henrion, Didier; Leipold, Manfred et al

in Advances in Space Research (2011), 48(11), 1922-1926

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See detailTransiting exoplanets from the CoRoT space mission - XIX. CoRoT-23b: a dense hot Jupiter on an eccentric orbit
Rouan, D.; Parviainen, H.; Moutou, C. et al

in Astronomy and Astrophysics (2011), 537

We report the detection of CoRoT-23b, a hot Jupiter transiting in front of its host star with a period of 3.6314 \pm 0.0001 days. This planet was discovered thanks to photometric data secured with the ... [more ▼]

We report the detection of CoRoT-23b, a hot Jupiter transiting in front of its host star with a period of 3.6314 \pm 0.0001 days. This planet was discovered thanks to photometric data secured with the CoRoT satellite, combined with spectroscopic radial velocity (RV) measurements. A photometric search for possible background eclipsing binaries conducted at CFHT and OGS concluded with a very low risk of false positives. The usual techniques of combining RV and transit data simultaneously were used to derive stellar and planetary parameters. The planet has a mass of Mp = 2.8 \pm 0.3 MJup, a radius of Rpl = 1.05 \pm 0.13 RJup, a density of \approx 3 g cm-3. RV data also clearly reveal a non zero eccentricity of e = 0.16 \pm 0.02. The planet orbits a mature G0 main sequence star of V =15.5 mag, with a mass M\star = 1.14 \pm 0.08 M\odot, a radius R\star = 1. 61 \pm 0.18 R\odot and quasi-solar abundances. The age of the system is evaluated to be 7 Gyr, not far from the transition to subgiant, in agreement with the rather large stellar radius. The two features of a significant eccentricity of the orbit and of a fairly high density are fairly uncommon for a hot Jupiter. The high density is, however, consistent with a model of contraction of a planet at this mass, given the age of the system. On the other hand, at such an age, circularization is expected to be completed. In fact, we show that for this planetary mass and orbital distance, any initial eccentricity should not totally vanish after 7 Gyr, as long as the tidal quality factor Qp is more than a few 105, a value that is the lower bound of the usually expected range. Even if Corot-23b features a density and an eccentricity that are atypical of a hot Jupiter, it is thus not an enigmatic object. [less ▲]

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See detailRotation on the oscillation spectrum of solar-like stars
Suárez, J. C.; Goupil, M.-J.; Reese, Daniel ULg et al

in Alecian, G.; Belkacem, K.; Samadi, R. (Eds.) et al SF2A-2011: Proceedings of the Annual meeting of the French Society of Astronomy and Astrophysics (2011, December 01)

One of the main sources of uncertainty in the asteroseismic models of solar-like stars is the poor match between predicted oscillation frequencies and observed ones in the very high frequency domain ... [more ▼]

One of the main sources of uncertainty in the asteroseismic models of solar-like stars is the poor match between predicted oscillation frequencies and observed ones in the very high frequency domain. Today, such deviation is usually corrected by fitting the affected frequencies with polynomials which are then physically explained by possible effects of turbulence, diffusion, etc., i.e., the so-called ``surface effects". In this work, we show that the effect of the stellar deformation due to rotation is of the same order or even larger than the aforementioned surface effects. Moreover, we show that rotation effects, even for the low velocities generally observed in solar-like stars, becomes important for the asteroseismic analysis and cannot be neglected when modeling such stars. [less ▲]

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See detailThérapie du mésothéliome pleural : compréhension des mécanismes de résistance à la chimiothérapie
Costa, Chrisostome ULg; Vandermeers, Fabian ULg; Reddy, NS Sathyanarayana ULg et al

Diverse speeche and writing (2011)

Thérapie du mésothéliome pleural : compréhension des mécanismes de résistance à la chimiothérapie. Chrisostome Costa 1, Fabian Vandermeers 2, Sathyanarayana Reddy 2, Céline Mascaux 3, Pascale Hubert 2 ... [more ▼]

Thérapie du mésothéliome pleural : compréhension des mécanismes de résistance à la chimiothérapie. Chrisostome Costa 1, Fabian Vandermeers 2, Sathyanarayana Reddy 2, Céline Mascaux 3, Pascale Hubert 2, Philippe Delvenne 2, Luc Willems 1,2 1 Laboratoire de biologie cellulaire et moléculaire, ULg, Gemboux Agro Bio-Tech, 13 av. Maréchal Juin, 5030 Gembloux ; Tél. : 32-(0)-81-622157 ; Fax : 32-(0)-81-6138 88 ; Courriel: ccosta@doct.ulg.ac.be 2 GIGA, ULg, Liège 3 Institut Bordet, ULB, Bruxelles - Introduction : Le mésothéliome pleural malin (MPM) est un cancer de la plèvre causé principalement par l’inhalation de fibres d’amiante. Nous avons montré précédemment que les inhibiteurs d’histones deacetylases (tel que le valproate, VPA) augmentent significativement l’efficacité des composés utilisés en chimiothérapie (pemetrexed et cisplatin) et prolonge la survie des patients atteints de MPM. Malheureusement, une proportion importante des patients développe une résistance au traitement de seconde ligne avec la doxorubicine et le VPA. - But du projet : L’objectif du travail est de disséquer les mécanismes qui régissent la réponse au traitement de seconde ligne du MPM. - Méthodes et résultats : Nous avons tout d’abord comparé deux types de lignées cellulaires présentant soit une sensibilité (cellules M14K) soit une résistance (cellules H28) au traitement combiné VPA+doxorubicine. En utilisant des microdamiers (Agilent), nous avons analysé le profil d’expression génique de cellules M14K et H28 traitées avec le VPA et la doxorubicine. Après quantification des fluorescences, une analyse statistique (Genespring GX) et une modélisation bioinformatique (Ingenuity) ont permis d’identifier les gènes candidats les plus relevants. En fonction de la p-value et du fold change, un nombre limité de gènes ont été sélectionnés et validés par la technique de qRT-PCR. Parmi ceux-ci, nous avons identifié le gène TGFA dont l’expression corrèle avec la résistance au traitement. En effet, nous avons observé que le niveau d’expression basale du gène TGFA est beaucoup plus important dans la lignée résistante H28 que dans la lignée sensible M14K. Dans le but de valider son implication dans la réponse à la thérapie, nous avons diminué (par interférence ARN) ou augmenté (par transfection d’un vecteur d’expression) l’expression de TGFA respectivement dans les lignées H28 ou M14K. Nous avons ensuite déterminé les taux d’apoptose en évaluant la fragmentation de l’ADN en présence de doxorubicine et de VPA. Les résultats montrent que la diminution de l’expression de TGFA permet une augmentation sensible de l’apoptose induite par le traitement combiné doxorubicine et VPA dans la lignée résistante H28 (de 9% à 36%). A l’inverse, la surexpression de TGFA est associée avec une diminution d’apoptose dans la lignée sensible M14K (de 28% à 18%). Ces observations ont été confirmées par une analyse de l’activité des caspases 3 et 7. En accord avec la propriété de la protéine TGFAd’induire la prolifération cellulaire via le récepteur à l’EGF, des inhibiteurs de l’activité tyrosine kinase (l’Iressa et le Tarceva) augmentent l’apoptose induite par la doxorubicine et le VPA dans la lignée résistante H28 (de 16% à 40%). L’efficacité du traitement combiné VPA+doxorubicine+Iressa/Tarceva est actuellement évaluée en modèle murin (souris SCID). - Conclusions : Nous avons identifié un gène, le TGFA, dont l’expression corrèle avec la résistance à l’apoptose induite par la doxorubicine et le VPA. L’utilisation d’inhibiteurs du récepteur EGF pourrait donc améliorer le traitement de seconde ligne du MPM. [less ▲]

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See detailSolutions and periodicity of satellite relative motion under even zonal harmonics perturbations
Martinusi, Vladimir ULg; Gurfil, Pini

in Celestial Mechanics and Dynamical Astronomy (2011), 111

Finding relative satellite orbits that guarantee long-term bounded relative motion is important for cluster flight, wherein a group of satellites remain within bounded distances while applying very few ... [more ▼]

Finding relative satellite orbits that guarantee long-term bounded relative motion is important for cluster flight, wherein a group of satellites remain within bounded distances while applying very few formationkeeping maneuvers. However, most existing astrodynamical approaches utilize mean orbital elements for detecting bounded relative orbits, and therefore cannot guarantee long-term boundedness under realistic gravitational models. The main purpose of the present paper is to develop analytical methods for designing long-term bounded relative orbits under high-order gravitational perturbations. The key underlying observation is that in the presence of arbitrarily high-order even zonal harmonics perturbations, the dynamics are superintegrable for equatorial orbits. When only J [SUB]2[/SUB] is considered, the current paper offers a closed-form solution for the relative motion in the equatorial plane using elliptic integrals. Moreover, necessary and sufficient periodicity conditions for the relative motion are determined. The proposed methodology for the J2-perturbed relative motion is then extended to non-equatorial orbits and to the case of any high-order even zonal harmonics ( J2n, n ≥ 1). Numerical simulations show how the suggested methodology can be implemented for designing bounded relative quasiperiodic orbits in the presence of the complete zonal part of the gravitational potential. [less ▲]

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See detailLa disposition générale anti-abus de l'article 344, § 1er, CIR/92
Bourgeois, Marc ULg

Conference (2011, December 01)

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See detailSaturn's aurora as viewed by Cassini VIMS
Melin, H.; Stallard, T.; Badman, S. V. et al

Conference (2011, December 01)

The stunning views of the kronian aurora captured by the Visual and Infrared Imaging Spectrograph (VIMS) onboard the Cassini spacecraft continues to provide crucial observations of the fervent interaction ... [more ▼]

The stunning views of the kronian aurora captured by the Visual and Infrared Imaging Spectrograph (VIMS) onboard the Cassini spacecraft continues to provide crucial observations of the fervent interaction between the upper atmosphere and the magnetosphere of Saturn. Here, we present recent findings of VIMS auroral research, which includes both statistical studies and case studies of auroral events and morphology. In addition to stand-alone observations, there is a small subset of VIMS observations during which UVIS was also acquiring data. These observations enable the comparison between observations of H, H2 in the ultraviolet and H3+ in the infrared that are both spatially overlapping and temporally simultaneous. Whilst emission tends to coincide for these three species on the main oval, there are significant differences both pole-ward and equator-ward, such that observations of H and H2 is generally a poor proxy for emissions of H3+. VIMS is sensitive to infrared thermal emission from the H3+ molecule, which is formed very efficiently via the ionisation of H2. Therefore, the morphology of H3+ emission becomes a tracer of energy injected into the upper atmosphere - the most striking of which is auroral particle precipitation. [less ▲]

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