References of "2010"
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See detailImagerie de la microcirculation cutanée défaillante.
QUATRESOOZ, Pascale ULg; REGINSTER, Marie-Annick ULg; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2010), 123

Le réseau microvasculaire de la peau joue des rôles physiologiques majeurs en oxygénant les tissus et en permettant des échanges thermiques finement régulés. Son parcours résistif et capacitif module les ... [more ▼]

Le réseau microvasculaire de la peau joue des rôles physiologiques majeurs en oxygénant les tissus et en permettant des échanges thermiques finement régulés. Son parcours résistif et capacitif module les résistances périphériques au débit sanguin. La microvascularisation est sous l’influence de divers facteurs, mais globalement, elle semble presque immuable dans la peau saine. En revanche, certaines circonstances pathologiques engendrent des hyperplasies ou des hypoplasies vasculaires. Parfois aussi, le réseau semble garder son extension normale, mais sa structure intime est remaniée. Cette revue est un florilège d’aspects microscopiques associés à des perturbations majeures de la fonctionnalité vasculaire cutanée. [less ▲]

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See detailCentral neuromodulation in cluster headache patients treated with occipital nerve stimulators: A PET study
Magis, Delphine ULg; Bruno, Marie-Aurélie ULg; Fumal, Arnaud ULg et al

in Acta Neurologica Belgica (2010), 110(Suppl 1), 17

OBJECTIVES: Use functional brain imaging to explore activity changes in centres involved in trigeminal pain processing and control before and after occipital neurostimulation in drug-resistant chronic ... [more ▼]

OBJECTIVES: Use functional brain imaging to explore activity changes in centres involved in trigeminal pain processing and control before and after occipital neurostimulation in drug-resistant chronic cluster headache patients. BACKGROUND: Occipital nerve stimulation (ONS) provides relief to about 60% of patients suffering from drug-resistant chronic cluster headache (drCCH). Its mode of action, however, remains elusive, but the long latency to meaningful effect suggests that ONS induces slow neuromodulation. METHODS: Ten drCCH patients underwent an 18FDG-PET scan after ONS durations varying between 0 and 30 months. All were scanned with ongoing ONS (ON) and with the stimulator switched OFF. RESULTS: After 6-30 months of ONS, 3 patients were pain free and 4 had a ≥ 90% reduction of attack frequency (responders). In patients overall compared to controls, several areas of the pain matrix were hypermetabolic: ipsilateral hypothalamus, midbrain and ipsilateral lower pons. All normalized after ONS, except the hypothalamus. Switching ON or OFF the stimulator had little influence on brain glucose metabolism. The perigenual anterior cingulate cortex (PACC) was hyperactive in ONS responders compared to non-responders. INTERPRETATION AND CONCLUSIONS: Metabolic normalization in the pain neuromatrix and lack of short-term changes induced by the stimulation support the hypothesis that ONS acts in drCCH through slow neuromodulatory processes. Selective activation in responders of PACC, a pivotal structure in the endogenous opioid system, suggests that ONS may restore balance within dysfunctioning pain control centres. That ONS is nothing but a symptomatic treatment might be illustrated by the persistent hypothalamic hypermetabolism which could explain why autonomic attacks may persist despite pain relief and why cluster attacks recur shortly after stimulator arrest. [less ▲]

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See detailLe comportement suicidaire chez l'enfant
Malchair, Alain ULg

in Revue Médicale de Liège (2010), 65(2), 67-70

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See detailValidation of a model-based virtual trials method for tight glycemic control in intensive care.
Chase, J Geoffrey; Suhaimi, Fatanah; Penning, Sophie ULg et al

in BioMedical Engineering OnLine (2010), 9

BACKGROUND: In-silico virtual patients and trials offer significant advantages in cost, time and safety for designing effective tight glycemic control (TGC) protocols. However, no such method has fully ... [more ▼]

BACKGROUND: In-silico virtual patients and trials offer significant advantages in cost, time and safety for designing effective tight glycemic control (TGC) protocols. However, no such method has fully validated the independence of virtual patients (or resulting clinical trial predictions) from the data used to create them. This study uses matched cohorts from a TGC clinical trial to validate virtual patients and in-silico virtual trial models and methods. METHODS: Data from a 211 patient subset of the Glucontrol trial in Liege, Belgium. Glucontrol-A (N = 142) targeted 4.4-6.1 mmol/L and Glucontrol-B (N = 69) targeted 7.8-10.0 mmol/L. Cohorts were matched by APACHE II score, initial BG, age, weight, BMI and sex (p > 0.25). Virtual patients are created by fitting a clinically validated model to clinical data, yielding time varying insulin sensitivity profiles (SI(t)) that drives in-silico patients.Model fit and intra-patient (forward) prediction errors are used to validate individual in-silico virtual patients. Self-validation (tests A protocol on Group-A virtual patients; and B protocol on B virtual patients) and cross-validation (tests A protocol on Group-B virtual patients; and B protocol on A virtual patients) are used in comparison to clinical data to assess ability to predict clinical trial results. RESULTS: Model fit errors were small (<0.25%) for all patients, indicating model fitness. Median forward prediction errors were: 4.3, 2.8 and 3.5% for Group-A, Group-B and Overall (A+B), indicating individual virtual patients were accurate representations of real patients. SI and its variability were similar between cohorts indicating they were metabolically similar.Self and cross validation results were within 1-10% of the clinical data for both Group-A and Group-B. Self-validation indicated clinically insignificant errors due to model and/or clinical compliance. Cross-validation clearly showed that virtual patients enabled by identified patient-specific SI(t) profiles can accurately predict the performance of independent and different TGC protocols. CONCLUSIONS: This study fully validates these virtual patients and in silico virtual trial methods, and clearly shows they can accurately simulate, in advance, the clinical results of a TGC protocol, enabling rapid in silico protocol design and optimization. These outcomes provide the first rigorous validation of a virtual in-silico patient and virtual trials methodology. [less ▲]

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See detailAxion-like particles and circular polarisation of active galactic nuclei
Payez, Alexandre ULg; Cudell, Jean-René ULg; Hutsemekers, Damien ULg

in Jaeckel, Joerg; Lindner, Axel; Redondo, Javier (Eds.) Proceedings of the 5th Patras Workshop on Axions, WIMPs and WISPs PATRAS 2009 (2010)

The measurements of the linear polarisation of visible light from quasars give strong evidence for large-scale coherent orientations of their polarisation vectors in some regions of the sky. We show that ... [more ▼]

The measurements of the linear polarisation of visible light from quasars give strong evidence for large-scale coherent orientations of their polarisation vectors in some regions of the sky. We show that these observations can be explained by the mixing of the photons with very light pseudoscalar (axion-like) particles in extragalactic magnetic fields during their propagation. We present a new treatment in terms of wave packets and discuss the circular polarisation. [less ▲]

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See detailReduced organ failure with effective glycemic control
PREISER, Jean-Charles ULg; Chase, J. G.; Pretty, C. G. et al

in Intensive Care Medicine (2010), 36(2), 173-173

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See detailLifetime measurements and transition probabilities in Mo II
Lundberg, H; Engström, L; Hartman, H et al

in Journal of Physics : B Atomic Molecular & Optical Physics (2010), 43

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See detailFrom Non-invasive Site Characterization to Site Amplification: Recent Advances in the Use of Ambient Vibration Measurements.
Bard, P-Y; et al.; Havenith, Hans-Balder ULg

in Geotechnical, Geological and Earthquake Engineering : Earthquake Engineering in Europe (2010)

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See detailÀ quelles conditions la formation initiale peut-elle contribuer au développement professionnel des enseignants et formateurs d’enseignants
Beckers, Jacqueline ULg

in Paquay, L.; Wouters, P.; Van Nieuwenhoven, C. (Eds.) Évaluation et développement professionnel (2010)

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See detailA new type of cubic-stacked layer structure in anthoinite, AlWO3(OH3)
Grey, I.; Madsen, I.; Mills et al

in American Mineralogist (2010), 95

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See detailChimie (3e partie)
Heinrichs, Benoît ULg

Learning material (2010)

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See detailInterfacial area measurement in a catalytic distillation packing using high energy x-ray CT
Aferka, Saïd ULg; Marchot, Pierre ULg; Crine, Michel ULg et al

in Chemical Engineering Science (2010), 65(1), 511-516

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on ... [more ▼]

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on processing of tomographic images. It is validated by comparing specific surface area determined on dry packings (Mellapak™ 752Y and Katapak™ SP12) tomographic binary images (gas and solid) to values announced by manufacturers, based on geometrical considerations. These data agree fairly well. However, tomographic images show that the specific area is not distributed uniformly over the height of a packing element due to the presence of perforations in corrugated sheets and of wall wipers between the packing and the column wall. X-ray tomography is a unique technique to access to the spatial distribution of these geometrical details in a non-intrusive way. The method used to determine the specific surface area of dry packing is then applied to irrigated packing in order to determine the gas–liquid interfacial area. The axial distribution of the interfacial area is non-uniform and is correlated to the packing specific area. The maxima of the specific surface area correspond to the presence of wall wipers. The gas–liquid interfacial area averaged over the column length is determined. It increases logically with the liquid superficial velocity and slightly with the gas velocity. The effect of the gas velocity is however more pronounced when reaching loading point. [less ▲]

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See detailEstimation in nonparametric location-scale regression models with censored data
Heuchenne, Cédric ULg; Van Keilegom, Ingrid

in Annals of the Institute of Statistical Mathematics (2010), 62

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See detailRésolution de problèmes et représentations : construction de dessins libres ou utilisation de schémas prédéfinis ?
Fagnant, Annick ULg; Vlassis, Joëlle

in Congrès international. Actualité de al recherche en éducation et en formation. AREF 2010 (2010)

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See detailMise au point de l’indice composition dans le cadre de l’indicateur phytoplancton - les indices de composition phytoplanctonique en eaux côtières : synthèse bibliographique
Goffart, Anne ULg

Report (2010)

Ce rapport rappelle brièvement pourquoi le phytoplancton est un excellent indicateur de l’état des eaux côtières et synthétise les limites adaptatives des communautés phytoplanctoniques en réponse aux ... [more ▼]

Ce rapport rappelle brièvement pourquoi le phytoplancton est un excellent indicateur de l’état des eaux côtières et synthétise les limites adaptatives des communautés phytoplanctoniques en réponse aux perturbations d’origine anthropique (essentiellement l’enrichissement en sels nutritifs). Il présente ensuite l’indicateur phytoplanctonique idéal et résume l’état des connaissances en matière d’indices de composition et d’indicateurs phytoplanctoniques intégrant la composition. Les méthodes de calcul des indices sont expliquées lorsque les informations disponibles sont suffisamment claires et détaillées. Le rapport se termine par la proposition de pistes à explorer pour la mise au point et la validation d’un indice de composition phytoplanctonique qui soit opérationnel et représentatif de la composition taxonomique d’une masse d’eau côtière et de son évolution temporelle. [less ▲]

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See detailCOMPUTING ANTICIPATORY SYSTEMS, CASYS'09 - Ninth International Conference, Liège, Belgium, 3-8 August 2009
Dubois, Daniel ULg

Book published by American Institute of Physics (2010)

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