References of "2010"
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See detailNAVA enhances ventilatory variability and diaphragmaticactivity/tidal volume coupling
Moorhead, K.; Piquilloud, L.; Desaive, Thomas ULg et al

in Intensive Care Medicine (2010), 36(2), 326-326

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See detailCes nombres qu'on dit imaginaires sont-ils des nombres ?
Rosseel, Hilda; Schneider-Gilot, Marguerite ULg

Book published by Presses Universitaires de Liège (2010)

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See detailLes donations d'entreprises en region wallonne
Douny, Raphaël ULg

in Manuel de planification patrimoniale (2010)

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See detailHigher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.
El Hour, Mehdi ULg; Moncada-Pazos, A.; Blacher, Silvia ULg et al

in Oncogene (2010), 29(20), 3025-32

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in ... [more ▼]

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in tissue remodeling and angiogenesis associated with physiological and pathological processes. To elucidate the in vivo functions of ADAMTS-12, we have generated a knockout mouse strain (Adamts12−/−) in which Adamts12 gene was deleted. The mutant mice had normal gestations and no apparent defects in growth, life span and fertility. By applying three different in vivo models of angiogenesis (malignant keratinocyte transplantation, Matrigel plug and aortic ring assays) to Adamts12−/− mice, we provide evidence for a protective effect of this host enzyme toward angiogenesis and cancer progression. In the absence of Adamts-12, both the angiogenic response and tumor invasion into host tissue were increased. Complementing results were obtained by using medium conditioned by cells overexpressing human ADAMTS-12, which inhibited vessel outgrowth in the aortic ring assay. This angioinhibitory effect of ADAMTS-12 was independent of its enzymatic activity as a mutated inactive form of the enzyme was similarly efficient in inhibiting endothelial cell sprouting in the aortic ring assay than the wild-type form. Altogether, our results show that ADAMTS-12 displays antiangiogenic properties and protect the host toward tumor progression. [less ▲]

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See detailOn a class of micromechanical damage models with initial stresses for geomaterials
Levasseur, Séverine ULg; Collin, Frédéric ULg; Charlier, Robert ULg et al

in Mechanics Research Communications (2010), 37

In this paper, we extend a class of micromechanical damage models by including initial stresses. The proposed approach is based on the solution of the Eshelby inhomogeneous inclusion problem in the ... [more ▼]

In this paper, we extend a class of micromechanical damage models by including initial stresses. The proposed approach is based on the solution of the Eshelby inhomogeneous inclusion problem in the presence of a prestress (in the matrix), adapted for elastic voided media. The closed form expression of the corresponding energy potential is used as the basis of various isotropic damage models corresponding to three standard homogenization schemes. These models are illustrated by considering isotropic tensile loadings with different initial stresses. Finally, still in the isotropic context, we provide an interpretation of the macroscopic damage model formulated by Halm-Dragon (1996) by briefly connecting it to the present study. [less ▲]

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See detailFamilial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease.
Joossens, Marie; Van Steen, Kristel ULg; Branche, Julien et al

in Inflammatory Bowel Diseases (2010), 16(1), 58-67

BACKGROUND:: An increased risk of Crohn's disease (CD) has been reported consistently in first-degree relatives of patients. Our aim was to test whether a combination of CD-associated genes involved in ... [more ▼]

BACKGROUND:: An increased risk of Crohn's disease (CD) has been reported consistently in first-degree relatives of patients. Our aim was to test whether a combination of CD-associated genes involved in innate immunity and/or antibody responses to microbial antigens may be valuable in identifying healthy relatives at risk. METHODS:: We investigated 86 families from Belgium and northern France, 45 with at least 3 first-degree relatives with CD, 24 with a single case, and 17 control families without inflammatory bowel disease (IBD). The cohort consisted of 186 CD patients, 290 healthy relatives, and 142 controls (total 618). Genetic (NOD2, NOD1, TLR4, CARD8) and serologic markers (ASCA, ACMA, ALCA, ACCA, ASigmaMA, OmpC, CBir1, I2) were determined in all subjects. All Belgian families were prospectively followed up for 54 months. RESULTS:: In multiple-affected families, an increment of affected first-degree relatives and of positive antibodies were additive risks factors for CD (P < 0.0001), independent of NOD2 mutations. When comparing subjects from multiple-affected families, having 3 additional first-degree relatives with CD and 1 additional positive antibody increased the odds for CD to 9.19 (95% confidence interval [CI]: 4.07-20.80). After a follow-up of 54 months among all Belgian families, a total of 4 new diagnoses of IBD were confirmed in the multiple-affected families only, resulting in a 57-fold increase in incidence within multiple-affected families compared to the known incidence of IBD in our region. CONCLUSIONS:: We found an additive risk increment for CD in subjects from multicase families per additional affected relative and per additional positive antibody, independent of NOD2. Furthermore, a very high disease incidence was observed in these multiple-affected families. Inflamm Bowel Dis 2010. [less ▲]

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See detailOn the origin of Saturn's outer auroral emission
Grodent, Denis ULg; Radioti, Aikaterini ULg; Bonfond, Bertrand ULg et al

in Journal of Geophysical Research. Space Physics (2010), 115

Ultraviolet Hubble Space Telescope images reveal a faint but distinct auroral emission equatorward of the main ring of emission of Saturn's southern polar region. This outer auroral emission is only ... [more ▼]

Ultraviolet Hubble Space Telescope images reveal a faint but distinct auroral emission equatorward of the main ring of emission of Saturn's southern polar region. This outer auroral emission is only visible near the nightside limb for the strongly tilted viewing geometry achieved in January 2004. We model the limb-brightening amplification of this emission, and we show that the observations are compatible with an ∼7° wide emission ring approximately centered on the 67°S parallel. The 1.7 kR brightness of this emission requires an injected electron energy flux of ∼0.3 mW m[SUP]‑2[/SUP]. The outer auroral emission maps to a region of the equatorial plane between 4 and 11 R[SUB]S[/SUB]. We suggest that a population of suprathermal electrons observed by Cassini can provide more than the required energy flux without the need for field-aligned acceleration. This auroral UV emission may also be associated with energetic neutral oxygen and hydrogen atoms originating from the energetic protons and O[SUP]+[/SUP] of magnetosphere and/or with a secondary infrared auroral oval. [less ▲]

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See detailLes seniors délocalisés et leur patrimoine – questions choisies de droit international privé
Wautelet, Patrick ULg

in Georges, Frédéric (Ed.) Le droit des seniors : aspects civils, sociaux et fiscaux (2010)

In this paper, I examine the legal position of migrants - both of foreigners who have settled some time ago in Belgium and of Belgian citizens who have settled abroad. The focus is in particular on two ... [more ▼]

In this paper, I examine the legal position of migrants - both of foreigners who have settled some time ago in Belgium and of Belgian citizens who have settled abroad. The focus is in particular on two issues which are of interest to elders and senior citizens, i.e. that of their successions (to whom will my assets be distributed after I pass away) and of the impact of mental or physical incapacity (what if I am unable to manage my assets). [less ▲]

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See detailNutritional value and intake of aquatic ferns (Azolla filiculoides Lam. and Salvinia molesta Mitchell.) in sows
Leterme, Pascal; Londoño, Angela M.; Ordoñez, Diana C. et al

in Animal Feed Science & Technology (2010), 155(1), 55-64

Aquatic ferns (AFs) such as Azolla filiculoides and Salvinia molesta are grown on swine lagoons in the tropics and used in diets for pigs. The present work is aimed at evaluating their potential as feed ... [more ▼]

Aquatic ferns (AFs) such as Azolla filiculoides and Salvinia molesta are grown on swine lagoons in the tropics and used in diets for pigs. The present work is aimed at evaluating their potential as feed ingredients for sows. When presented with ad libitum AFs, gilts weighing 110 ± 14 kg (mean ± SD), were able to ingest 9.1–9.7 kg fresh AF per day (from 597 to 630 g dry matter (DM) per day) and from 1240 to 1428 g DM per day when presented in a dry, ground form. A digestibility study was conducted, using sows weighing 213 ± 9 kg (mean ± SD), which were fed diets containing maize, soybean meal and 0, 150 or 300 g AF kg−1 diet. The presence of AFs had a negative impact on the faecal digestibility of the crude protein, NDF and energy content of the whole diet (P<0.001) and on the ileal protein digestibility, especially with 300 g AFs kg−1 diet. The level of AFs in the diet had no effect on stomach weight (P>0.05) but increased the weight of the rest of the gastrointestinal tract (P<0.001). The rate of AF fibre fermentation in the pig large intestine was measured using an in vitro gas test. The rates were much lower than tropical tree foliage, which can also be used in pig diets in the tropics. This could partly explain the low apparent digestibility of AFs in pigs. In conclusion, the inclusion level of AFs in rations for sows should be limited to 150 g AFs kg−1 diet due to the low digestibility and energy density, as well as the negative impact on the digestibility of the whole diet. [less ▲]

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See detailMusique et expression politique des minorités ethniques et raciales
Martiniello, Marco ULg

Scientific conference (2010)

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See detailImputation of genotypes from different single nucleotide polymorphism panels in dairy cattle.
Druet, Tom ULg; Schrooten, C.; de Roos, A. P. W.

in Journal of Dairy Science (2010), 93(11), 5443-54

Imputation of missing genotypes is important to join data from animals genotyped on different single nucleotide polymorphism (SNP) panels. Because of the evolution of available technologies, economical ... [more ▼]

Imputation of missing genotypes is important to join data from animals genotyped on different single nucleotide polymorphism (SNP) panels. Because of the evolution of available technologies, economical reasons, or coexistence of several products from competing organizations, animals might be genotyped for different SNP chips. Combined analysis of all the data increases accuracy of genomic selection or fine-mapping precision. In the present study, real data from 4,738 Dutch Holstein animals genotyped with custom-made 60K Illumina panels (Illumina, San Diego, CA) were used to mimic imputation of genotypes between 2 SNP panels of approximately 27,500 markers each and with 9,265 SNP markers in common. Imputation efficiency increased with number of reference animals (genotyped for both chips), when animals genotyped on a single chip were included in the training data, with regional higher marker densities, with greater distance to chromosome ends, and with a closer relationship between imputed and reference animals. With 0 to 2,000 animals genotyped for both chips, the mean imputation error rate ranged from 2.774 to 0.415% and accuracy ranged from 0.81 to 0.96. Then, imputation was applied in the Dutch Holstein population to predict alleles from markers of the Illumina Bovine SNP50 chip with markers from a custom-made 60K Illumina panel. A cross-validation study performed on 102 bulls indicated that the mean error rate per bull was approximately equal to 1.0%. This study showed the feasibility to impute markers in dairy cattle with the current marker panels and with error rates below 1%. [less ▲]

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See detailRefining the taxonomy of the Rattini tribe: a phylogeny-based delimitation of species boundaries
Pagès, Marie ULg; Chaval, Yannick; Herbreteau, Vincent et al

in BMC Evolutionary Biology (2010), 10(184), 184

Background: Rodents are recognized as hosts for at least 60 zoonotic diseases and may represent a serious threat for human health. In the context of global environmental changes and increasing mobility of ... [more ▼]

Background: Rodents are recognized as hosts for at least 60 zoonotic diseases and may represent a serious threat for human health. In the context of global environmental changes and increasing mobility of humans and animals, contacts between pathogens and potential animal hosts and vectors are modified, amplifying the risk of disease emergence. An accurate identification of each rodent at a specific level is needed in order to understand their implications in the transmission of diseases. Among the Muridae, the Rattini tribe encompasses 167 species inhabiting South East Asia, a hotspot of both biodiversity and emerging and re-emerging diseases. The region faces growing economical development that affects habitats, biodiversity and health. Rat species have been demonstrated as significant hosts of pathogens but are still difficult to recognize at a specific level using morphological criteria. DNAbarcoding methods appear as accurate tools for rat species identification but their use is hampered by the need of reliable identification of reference specimens. In this study, we explore and highlight the limits of the current taxonomy of the Rattini tribe. <br />Results: We used the DNA sequence information itself as the primary information source to establish group membership and estimate putative species boundaries. We sequenced two mitochondrial and one nuclear genes from 122 rat samples to perform phylogenetic reconstructions. The method of Pons and colleagues (2006) that determines, with no prior expectations, the locations of ancestral nodes defining putative species was then applied to our dataset. To give an appropriate name to each cluster recognized as a putative species, we reviewed information from the literature and obtained sequences from a museum holotype specimen following the ancient DNA criteria. <br />Conclusions: Using a recently developed methodology, this study succeeds in refining the taxonomy of one of the most difficult groups of mammals. Most of the species expected within the area were retrieved but new putative species limits were also indicated, in particular within Berylmys and Rattus genera, where future taxonomic studies should be directed. Our study lays the foundations to better investigate rodent-born diseases in South East Asia and illustrates the relevance of evolutionary studies for health and medical sciences. [less ▲]

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See detailJacques Derrida : l'analyse spectrale de l'oeuvre d'art et la logique du parergon dans la troisième Critique kantienne
Steinmetz, Rudy ULg

in Steinmetz, Rudy; Lenain, Thierry (Eds.) Cadre, seuil, limite. La question de la frontière dans la théorie des arts (2010)

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See detailcompte rendu de : Benjamin W. FORTSON IV, Language and Rhythm in Plautus : Synchronic and Diachronic Studies
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2010), 79

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See detailExercices d'astronomie de position
Bidaine, Benoît ULg

Learning material (2010)

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See detailPoultry supply chains and challenge facing the poultry smallholders in Hanoi suburban
Phan Dang, Thang; Duquesne, Brigitte ULg; Lebailly, Philippe ULg et al

in Vietnam’s Socio-Economic Development [=VSED]: a Social Science Review (2010), September 2010(63), 64-80

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See detailcompte rendu de : Florence DUPONT et Emmanuelle VALETTE-CAGNAC Façons de parler grec à Rome
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (2010), 69(3), 884-885

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See detailLes traces de vie au Précambrien et la fossilisation
Javaux, Emmanuelle ULg

Conference (2010)

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