References of "2010"
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See detailLes arts visuels dans la genèse de Salammbô
Wicky, Erika ULg

in Revue des lettres modernes (2010), (7),

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See detailSHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity
Charlier, Edith ULg; Condé, Claude ULg; Zhang, Jing et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2010)

SHIP-1 functions as a negative regulator of immune responses by hydrolyzing phosphatidylinositol-3,4,5-triphosphate generated by PI 3-kinase activity. As a result, SHIP-1 deficiency in mice results in ... [more ▼]

SHIP-1 functions as a negative regulator of immune responses by hydrolyzing phosphatidylinositol-3,4,5-triphosphate generated by PI 3-kinase activity. As a result, SHIP-1 deficiency in mice results in myeloproliferation and B cell lymphoma. On the other hand, SHIP-1 deficient mice have a reduced T cell population, but the underlying mechanisms are unknown. In this work, we hypothesized that SHIP-1 plays anti-apoptotic functions in T cells upon stimulation of the death receptor CD95/APO-1/Fas. Using primary T cells from SHIP-1-/- mice and T leukemic cell lines, we report here that SHIP-1 is a potent inhibitor of CD95-induced death. We observed that a small fraction of the SHIP-1 pool is localized to the endoplasmic reticulum where it promotes CD95 glycosylation. This post-translational modification requires an intact SH2 domain of SHIP-1, but is independent of its phosphatase activity. The glycosylated CD95 fails to oligomerize upon stimulation, resulting in impaired DISC formation and downstream apoptotic cascade. These results uncover an unanticipated inhibitory function for SHIP-1 and emphasize the role of glycosylation in the regulation of CD95 signaling in T cells. This work may also provide a new basis for therapeutic strategies using compounds inducing apoptosis through the CD95 pathway on SHIP-1 negative leukemic T cells. [less ▲]

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See detailL'économie sociale: le risque caritatif d'un projet politique
Frère, Bruno ULg

Article for general public (2010)

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See detailCarte hydrogéologique de Wallonie 1/25000. 65/5-6, Sainte-Marie-Chevigny - Sibret
Bouezmarni, Mohamed ULg; Denne, Pierre; Debbaut, Vincent ULg

Cartographic material (2010)

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See detailAnalysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk
Mahachie John, Jestinah ULg; Baurecht, H.; Rodriguez, E. et al

in Allergy (2010), 65(7), 875-882

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S ... [more ▼]

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S. Analysis of the high-affinity IgE receptor genes reveals epistatic effects of FCER1A variants on total IgE levels and eczema risk. Allergy 2009; DOI: 10.1111/j.1398-9995.2009.02297.x. Abstract Background: High levels of total and allergen-specific IgE levels are a key feature in allergic diseases. The high-affinity receptor for IgE, which is composed of one alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits, represents the central receptor of IgE-induced reactions. In a genome-wide association scan, we recently identified associations between functional FCER1A variants and total serum IgE levels. Previous studies had reported linkage and association of FCER1B variants with IgE and atopic traits. The FCER1G gene has not yet been investigated with regard to atopy. Filaggrin (FLG) is the strongest known risk gene for eczema, in particular the allergic subtype of eczema. Methods: We investigated the association of FCER1A, FCER1B, and FCER1G variants with IgE in a large population-based cohort (n = 4261) and tested for epistatic effects using the model-based multifactor dimensionality reduction (MB-MDR) method. In addition, we investigated a potential interaction between FLG and FCER1A variants in a large collection of eczema cases (n = 1018) and population controls. Results: Three strongly correlated FCER1A polymorphisms were significantly associated with total and specific IgE levels as well as allergic sensitization. No associations were seen for FCER1B and FCER1G. After adjustment for FLG effects, a significant epistatic effect of the FCER1A variants rs10489854 and rs2511211 on eczema risk was detected. Conclusions: These results suggest that FCER1A variants by themselves and in combination influence IgE levels and act synergistically to influence eczema risk. [less ▲]

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See detailFormer des enseignants francophones pour de nouveaux publics
Defays, Jean-Marc ULg

in Cadet-Joseph, Lucile; Pellegrini, Florence (Eds.) Situation et perspectives d'évolution des départements d'études française des universités européennes (2010)

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See detailCyprinid herpesvirus 3
Michel, Benjamin; Fournier, Guillaume; Lieffrig, François et al

in Emerging Infectious Diseases (2010), 16

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See detailDECONSTRUCTION ARCHITECTURALE; PORTRAIT D’UN MONDE TEXTOCENTRIQUE. Approche théorique et philosophique d'un new paradigm, 1988 – 2010
Bodart, Céline ULg

Master's dissertation (2010)

L'enjeu de ce mémoire était d'approcher, à travers la pensée de la déconstruction derridienne, l'interdisciplinarité établie entre architecture et philosophie comme l'origine d'un travail subversif ... [more ▼]

L'enjeu de ce mémoire était d'approcher, à travers la pensée de la déconstruction derridienne, l'interdisciplinarité établie entre architecture et philosophie comme l'origine d'un travail subversif aujourd'hui responsable de la crise sémantique traversée par l'art de la construction. Nous avons donc, à travers un parcours historique, reconstruit la genèse de ce phénomène à partir des théories écrites par ses architectes protagonistes et réévalué la filiation qu'on leur attribuait avec la philosophie de Jacques Derrida. Ensuite, nous avons étudié comment la pression médiatique s'est emparée de cette « pseudo-théorie », simplifiant et caricaturant l'ambition de son véritable discours. En définitive, ce mémoire, portrait d'une architecture devenue tour à tour hôte et victime de la subversion, a tenu l'hypothèse de l'existence en architecture d'un glissement référentiel semblable à celui de l'art vers le non-art. Nous avons tenté de démontrer que la déconstruction, se faisant expérience architecturale, a redessiné la carte des limites disciplinaires traditionnellement tenues par l'art de la construction. [less ▲]

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See detailMicrowave-Assisted Synthesis of 1,3-Dimesitylimidazolinium Chloride
Hans, Morgan ULg; Delaude, Lionel ULg

in Wipf, Peter (Ed.) Organic Syntheses. Volume 87 (2010)

A procedure for the microwave-assisted synthesis of 1,3-dimesitylimidazolinium chloride on a preparative scale is described starting from simple, commercially available reagents. Prior to a microwave ... [more ▼]

A procedure for the microwave-assisted synthesis of 1,3-dimesitylimidazolinium chloride on a preparative scale is described starting from simple, commercially available reagents. Prior to a microwave-assisted cyclization, it involves the formation of N,N'-dimesitylethane-1,2-diamine dihydrochloride via condensation of glyoxal with two equivalents of mesitylamine, followed by reduction of the intermediate Schiff base with sodium borohydride under acidic conditions. All three steps proceed readily under normal atmosphere. Laboratory grade solvents and reagents taken straight from the bottles do not require any additional purification. The two intermediates and the final product are isolated in high yield and purity by simple filtration and washing and may be used without any further purification for most applications. [less ▲]

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See detailManagement effects on net ecosystem carbon and GHG budgets at European crop sites
Ceschia, E.; Beziat, P.; Dejoux, J. F. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailCes nombres qu'on dit imaginaires sont-ils des nombres ?
Rosseel, Hilda; Schneider-Gilot, Marguerite ULg

Book published by Presses Universitaires de Liège (2010)

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See detailLa Soudière des Trois Lucs (Marseille) - Études historiques
Olive, Gilles ULg

in Newsletter MIP Provence (2010), 1(2010-05), 1-19

L'article décrit les recherches historiques sur une soudière du 19e siècle aux 3 Lucs à Marseille afin de la localiser avec précision et peut être trouver des ruines.

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See detailImagerie fonctionnelle et audition.
MAUDOUX, Audrey ULg; Poirrier, Anne-Lise ULg; Lefèbvre, Philippe ULg et al

in Cahiers de l'Audition (Les) (2010)

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See detailSevrage tabagique en préopératoire: une période propice pour lutter contre l'inertie et le défaut d'observance
Deflandre, Eric; Degey, Y.; Clerdain, Anne-Michèle ULg et al

in Revue Médicale de Liège (2010), 65(5-6), 332-337

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See detailManagement effects on European cropland respiration
Eugster, W.; Moffat, A. M.; Ceschia, E. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailThe IMA-CNMNC dominant-constituent rule revisited and extended
Hatert, Frédéric ULg; Burke, Ernst

in Elements (2010), 6

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