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See detailQuantitative Microtexture Analysis of Carbonate Rocks Using Bireflectance Imaging
Jaimes Contreras, Rafael Antonio ULg; Pilawski, Dimitri; Califice, Arnaud ULg et al

in Proceedings IAMG 2010 (2010)

Microtextural analysis of rocks has been addressed by several authors as an essential means to better understand the natural genesis of the material. But, it is also of paramount importance to those who ... [more ▼]

Microtextural analysis of rocks has been addressed by several authors as an essential means to better understand the natural genesis of the material. But, it is also of paramount importance to those who try to predict the geotechnical or industrial behaviour of a rock under many forms of solicitation (mechanical, thermal, etc.). Quantitative modal (phase) analysis using point counting has already been discussed in depth by authors such as Chayes more than fifty years ago. Nowadays, automated image analysis with millions of pixels is easily available and improves statistical accuracy provided the classification step is correctly performed. Spitefully the assignment of a pixel to a given mineral phase or to a given crystal is often poorly satisfactory and remains the bottleneck of a fully automated textural analysis. Methods using a manual rotation of a polarizer in transmitted light microscopy have been developed by Starkey and Samantaray (1993) and further automated and improved by Fueten (1997). These allow to better delineate individual crystals in a thin section due to contrast in birefringence. In this paper a similar technique using multiple orientations of a polarizer in reflected light microscopy has been used to contrast individual crystals in carbonated rocks. The maximum and minimum grey levels registered for each pixel allow for computing a bireflectance image whose variance is a good indicator of the misalignment of cristallographical orientations in the section. Moreover, the maximum of the reflectance gradient obtained for each orientation generates a good image of the grain boundaries and the presence of pores. This last one is quantitatively analysed using the intercept method to estimate the mean and variance of the grain size distribution. The paper presents a quantitative comparison of several different microtextures. [less ▲]

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See detailFunctional interplay between macroH2A and Polycomb Repressive Complexes
Creppe, Catherine ULg; Valero, Vanesa; Di Croce, Luciano et al

Poster (2010)

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See detailLes deux laïcités
Jacquemain, Marc ULg

Learning material (2010)

Le document synthétise ce qui semble la ligne de fracture majeure au sein de la laïcité franco-belge : opposition entre une conception "républicaine" et une conception "libérale". Les deux peuvent se ... [more ▼]

Le document synthétise ce qui semble la ligne de fracture majeure au sein de la laïcité franco-belge : opposition entre une conception "républicaine" et une conception "libérale". Les deux peuvent se réclamer de la tradition laïque mais la première inclut une forme d'hostilité de principe à la religion qui est étrangère à la seconde. Le document tente de synthétiser les principales conséquences politiques de ces deux conceptions en passant en revue la neutralité des agents de l'Etat, la neutralité des citoyens et des élèves, ainsi que les discriminations indirectes et les accommodements raisonnables. Sur ces quatre points, les deux conceptions de la laïcité conduisent à des positions politiques différentes. Normativement, le document défend la primauté réelle, mais pas inconditionnelle, de la liberté d'expression. [less ▲]

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See detailAnalysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk
Mahachie John, Jestinah ULg; Baurecht, H.; Rodriguez, E. et al

in Allergy (2010), 65(7), 875-882

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S ... [more ▼]

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S. Analysis of the high-affinity IgE receptor genes reveals epistatic effects of FCER1A variants on total IgE levels and eczema risk. Allergy 2009; DOI: 10.1111/j.1398-9995.2009.02297.x. Abstract Background: High levels of total and allergen-specific IgE levels are a key feature in allergic diseases. The high-affinity receptor for IgE, which is composed of one alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits, represents the central receptor of IgE-induced reactions. In a genome-wide association scan, we recently identified associations between functional FCER1A variants and total serum IgE levels. Previous studies had reported linkage and association of FCER1B variants with IgE and atopic traits. The FCER1G gene has not yet been investigated with regard to atopy. Filaggrin (FLG) is the strongest known risk gene for eczema, in particular the allergic subtype of eczema. Methods: We investigated the association of FCER1A, FCER1B, and FCER1G variants with IgE in a large population-based cohort (n = 4261) and tested for epistatic effects using the model-based multifactor dimensionality reduction (MB-MDR) method. In addition, we investigated a potential interaction between FLG and FCER1A variants in a large collection of eczema cases (n = 1018) and population controls. Results: Three strongly correlated FCER1A polymorphisms were significantly associated with total and specific IgE levels as well as allergic sensitization. No associations were seen for FCER1B and FCER1G. After adjustment for FLG effects, a significant epistatic effect of the FCER1A variants rs10489854 and rs2511211 on eczema risk was detected. Conclusions: These results suggest that FCER1A variants by themselves and in combination influence IgE levels and act synergistically to influence eczema risk. [less ▲]

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See detailEye gaze and conscious processing in severely brain-injured patients
Chatelle, Camille ULg; Laureys, Steven ULg; Majerus, Steve ULg et al

in Behavioral and Brain Sciences (2010), 33(6), 442-443

Niedenthal et al. discuss the importance of eye gaze in embodied simulation and, more globally, in the processing of emotional visual stimulation (such as facial expression). In this commentary, we ... [more ▼]

Niedenthal et al. discuss the importance of eye gaze in embodied simulation and, more globally, in the processing of emotional visual stimulation (such as facial expression). In this commentary, we illustrate the relationship between oriented eye movements, consciousness, and emotion by using the case of severely brain-injured patients recovering from coma (i.e., vegetative and minimally conscious patients). [less ▲]

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See detailMolecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation.
Yevenes, Gonzalo E; Moraga-Cid, Gustavo; Avila, Ariel et al

in Journal of Biological Chemistry (2010), 285(39), 30203-13

It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure. Thus, the differential ethanol ... [more ▼]

It is now believed that the allosteric modulation produced by ethanol in glycine receptors (GlyRs) depends on alcohol binding to discrete sites within the protein structure. Thus, the differential ethanol sensitivity of diverse GlyR isoforms and mutants was explained by the presence of specific residues in putative alcohol pockets. Here, we demonstrate that ethanol sensitivity in two ligand-gated ion receptor members, the GlyR adult alpha(1) and embryonic alpha(2) subunits, can be modified through selective mutations that rescued or impaired Gbetagamma modulation. Even though both isoforms were able to physically interact with Gbetagamma, only the alpha(1) GlyR was functionally modulated by Gbetagamma and pharmacological ethanol concentrations. Remarkably, the simultaneous switching of two transmembrane and a single extracellular residue in alpha(2) GlyRs was enough to generate GlyRs modulated by Gbetagamma and low ethanol concentrations. Interestingly, although we found that these TM residues were different to those in the alcohol binding site, the extracellular residue was recently implicated in conformational changes important to generate a pre-open-activated state that precedes ion channel gating. Thus, these results support the idea that the differential ethanol sensitivity of these two GlyR isoforms rests on conformational changes in transmembrane and extracellular residues within the ion channel structure rather than in differences in alcohol binding pockets. Our results describe the molecular basis for the differential ethanol sensitivity of two ligand-gated ion receptor members based on selective Gbetagamma modulation and provide a new mechanistic framework for allosteric modulations of abuse drugs. [less ▲]

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See detailE.C. Treaty & European Citizenship. Regional Integration and Cultural Diversity: the case of european citizenship
Carlier, Jean-Yves ULg

in Foblets; Dundes Renteln, Alison; Gaudreault-Desbiens, Jean-François (Eds.) Cultural Diversity and the Law. State Responses from (2010)

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See detailThe Nociception Coma Scale to assess nociception in disorders of consciousness
Chatelle, Camille ULg; Schnakers, Caroline; VANHAUDENHUYSE, Audrey ULg et al

Poster (2010)

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See detailEEG-based Brain Computer Interface for Locked-In Patients
Chatelle, Camille ULg; Combaz, Adrien

Scientific conference (2010)

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See detailConsciousness in coma and related states
Chatelle, Camille ULg

Conference (2010)

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See detailLa perception de la douleur chez les patients en éveil de coma
Chatelle, Camille ULg

Conference (2010)

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See detailManagement effects on net ecosystem carbon and GHG budgets at European crop sites
Ceschia, E.; Beziat, P.; Dejoux, J. F. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailThe IMA-CNMNC dominant-constituent rule revisited and extended
Hatert, Frédéric ULg; Burke, Ernst

in Elements (2010), 6

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See detailLa carrière et le milieu de vie des nouveaux migrants en Wallonie et à Bruxelles
Martiniello, Marco ULg; Triest, Frédéric

in Martiniello, Marco; Rea, Andrea; Timmerman, Christiane (Eds.) et al Nouvelles migrations et nouveaux migrants en Belgique (2010)

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See detailPresse et littérature africaines durant la période des indépendances : Analyse de la co-influence de deux supports engagés dans la défense d’une cause idéologique
Bassilua Nzuzi, Anicet ULg

in Cahier congolais de communication (2010)

The press and literature have played an important role in the Africa of the independences. They were used as forums through what the intellectual elite expressed its ideological struggle of independence ... [more ▼]

The press and literature have played an important role in the Africa of the independences. They were used as forums through what the intellectual elite expressed its ideological struggle of independence. Sometimes it was found a co-penetration of the two instruments, so that the authors of literature were those that animated the press and vice versa. This co-influence is particularly manifested by a transposition of the usual categories of a support on another. In our study, we examine the different forms that have taken such transfers. [less ▲]

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See detailPortfolio professionnel : Projet personnel :Enseignement de la nutrition en médecine vétérinaire : un projet d'exercices en ligne visant à susciter l'apprentissage pré-clinique et l'autonomie
Diez, Marianne ULg

Learning material (2010)

Portfolio présentant l'enseignement et une innovation pédagogique sous forme de 2 articles

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See detailL'émergence de modèles fonctionnels
Krysinska, Mariza; Schneider-Gilot, Marguerite ULg

Book published by Presses Universitaires de Liège (2010)

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