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See detailThe umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood.
Zeddou, Mustapha ULg; Briquet, Alexandra ULg; Relic, Biserka ULg et al

in Cell Biology International (2010), 34(7), 693-701

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these ... [more ▼]

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these cells can be isolated are still under discussion. Whereas BM (bone marrow) is presented as the main source of MSC, despite the invasive procedure related to this source, the possibility of isolating sufficient numbers of these cells from UCB (umbilical cord blood) remains controversial. Here, we present the results of experiments aimed at isolating MSC from UCB, BM and UCM (umbilical cord matrix) using different methods of isolation and various culture media that summarize the main procedures and criteria reported in the literature. Whereas isolation of MSC were successful from BM (10:10) and (UCM) (8:8), only one cord blood sample (1:15) gave rise to MSC using various culture media [DMEM (Dulbecco's modified Eagle's medium) +5% platelet lysate, DMEM+10% FBS (fetal bovine serum), DMEM+10% human UCB serum, MSCGM] and different isolation methods [plastic adherence of total MNC (mononuclear cells), CD3+/CD19+/CD14+/CD38+-depleted MNC and CD133+- or LNGFR+-enriched MNC]. MSC from UCM and BM were able to differentiate into adipocytes, osteocytes and hepatocytes. The expansion potential was highest for MSC from UCM. The two cell populations had CD90+/CD73+/CD105+ phenotype with the additional expression of SSEA4 and LNGFR for BM MSC. These results clearly exclude UCB from the list of MSC sources for clinical use and propose instead UCM as a rich, non-invasive and abundant source of MSC. [less ▲]

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See detailA new type of cubic-stacked layer structure in anthoinite, AlWO3(OH3)
Grey, I.; Madsen, I.; Mills et al

in American Mineralogist (2010), 95

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See detailStress Doppler echocardiography in valvular heart diseases: utility and assessment.
O'Connor, Kim; LANCELLOTTI, Patrizio ULg; Pierard, Luc ULg

in Future Cardiology (2010), 6(5), 611-25

This article is a review on the role of stress echocardiography in valvular heart diseases, describing what the validated indications are, how to perform the test and the utility of performing this ... [more ▼]

This article is a review on the role of stress echocardiography in valvular heart diseases, describing what the validated indications are, how to perform the test and the utility of performing this examination. Most valve diseases are characteristically dynamic and this dynamic component is best appreciated by exercise Doppler echocardiography. Dobutamine stress echocardiography is also useful in patients with severe aortic stenosis and left ventricular dysfunction. The main advantage of stress echocardiography is to concomitantly allow the evaluation of symptoms, exercise capacity and the hemodynamic consequences of valve diseases, especially in patients with severe valve diseases who deny symptoms or present equivocal symptoms. It also provides important prognostic information and may help to optimize surgical timing in difficult cases. Whether these data should be integrated in the management of patients needs further validation. [less ▲]

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See detail2-Point correlation function of nanostructured materials via the grey-tone correlation function of electron tomograms: A three-dimensional structural analysis of ordered mesoporous silica
Gommes, Cédric ULg; Friedrich, Heiner; De Jongh, Petra E et al

in Acta Materialia (2010), 58

Electron tomography is a unique technique for imaging the microstructure of materials with a nanometer resolution. The signal to noise ratio of electron tomograms is, however, often too low for a reliable ... [more ▼]

Electron tomography is a unique technique for imaging the microstructure of materials with a nanometer resolution. The signal to noise ratio of electron tomograms is, however, often too low for a reliable segmentation-based image analysis. We derive a general relation between the grey-tone correlation function of the tomograms and the 2-point correlation function of the morphology, which enables to analyze quantitatively the grey-tone correlation function with a morphological model of the material. The methodology is applied to SBA-15 ordered mesoporous silica. The three-dimensional grey-tone correlation function obtained from electron tomography is analyzed in terms of a hexagonal array of Gaussian independent pores. The model enables to relate the morphology obtained from the 2-point correlation function to macroscopic characterization data of the material, notably small-angle X-ray scattering and nitrogen adsorption. [less ▲]

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See detailLes deux laïcités
Jacquemain, Marc ULg

Learning material (2010)

Le document synthétise ce qui semble la ligne de fracture majeure au sein de la laïcité franco-belge : opposition entre une conception "républicaine" et une conception "libérale". Les deux peuvent se ... [more ▼]

Le document synthétise ce qui semble la ligne de fracture majeure au sein de la laïcité franco-belge : opposition entre une conception "républicaine" et une conception "libérale". Les deux peuvent se réclamer de la tradition laïque mais la première inclut une forme d'hostilité de principe à la religion qui est étrangère à la seconde. Le document tente de synthétiser les principales conséquences politiques de ces deux conceptions en passant en revue la neutralité des agents de l'Etat, la neutralité des citoyens et des élèves, ainsi que les discriminations indirectes et les accommodements raisonnables. Sur ces quatre points, les deux conceptions de la laïcité conduisent à des positions politiques différentes. Normativement, le document défend la primauté réelle, mais pas inconditionnelle, de la liberté d'expression. [less ▲]

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See detailProduction of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.
Ghalfi, H.; Benkerroum, N.; Ongena, Marc ULg et al

in Food Research International (2010), (43), 33-39

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See detailThe net biome production of full crop rotations in Europe
Kutsch, W. L.; Aubinet, Marc ULg; Buchmann, N. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailIMA Commission on New Minerals, Nomenclature and Classification (CNMNC), Newsletter 3
Williams, Pete; Hatert, Frédéric ULg; Pasero, Marco et al

in Mineralogical Magazine (2010), 74

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See detailMagnetic resonance signal changes during time in equine limbs refrigerated at 4 degrees C.
Bolen, Géraldine ULg; Haye, Dimitri; Dondelinger, Robert ULg et al

in Veterinary Radiology & Ultrasound (2010), 51(1), 19-24

When ex vivo magnetic resonance (MR) imaging studies are undertaken, specimen conservation should be taken into account when interpreting MR imaging results. The purpose of this study was to assess MR ... [more ▼]

When ex vivo magnetic resonance (MR) imaging studies are undertaken, specimen conservation should be taken into account when interpreting MR imaging results. The purpose of this study was to assess MR changes during time in the anatomic structures of the equine digit on eight cadaver limbs stored at 4 degrees C. The digits were imaged within 12 h after death and then after 1, 2, 7, and 14 days of refrigeration. After the last examination, four feet were warmed at room temperature for 24 h and reimaged. Sequences used were turbo spin echo (TSE) T1, TSE T2, short tau inversion recovery (STIR), and double-echo steady state (DESS). Images obtained were compared subjectively side by side for image quality and signal changes. Signal-to-noise ratio (SNR) was measured and compared between examinations. There were no subjective changes in image quality. A mild size reduction of the synovial recesses was detected subjectively. No signal change was seen subjectively except for bone marrow that appeared slightly hyperintense in STIR and slightly hypointense in TSE T2 sequence after refrigeration compared with day 0. Using quantitative analysis, significant SNR changes in bone marrow of refrigerated limbs compared with day 0 were detected in STIR and TSE T2 sequences. Warming at room temperature for 24 h produced a reverse effect on SNR compared with refrigeration with a significant increase in SNR in TSE T2 images. After 14 days of refrigeration a statistically significant decrease of SNR was found in bone marrow in TSE T2 and DESS sequences. The SNR in the deep digital flexor tendon was not characterized by significant change in SNR. [less ▲]

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See detailFaire un faux pas face a des syphilides "de deuxieme floraison".
El Hayderi, L.; Pierard, Gérald ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2010), 65(5-6), 420-2

In a recent past, the incidence of syphilis has increased in various geographical regions, particularly in urban areas. In addition, the disease is particularly associated with HIV infection. In secondary ... [more ▼]

In a recent past, the incidence of syphilis has increased in various geographical regions, particularly in urban areas. In addition, the disease is particularly associated with HIV infection. In secondary syphilis, the diagnosis may prove to be particularly difficult to reach because the clinico-pathological resemblance with other skin disorders is commonly high. The risk of diagnostic roaming is associated with therapeutic inertia which is highly prejudiciable to the patient. [less ▲]

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See detailCollective Annuities and Redistribution
Cremer, Helmuth; Lozachmeur, Jean-Marie; Pestieau, Pierre ULg

in Journal of Public Economic Theory (2010), (12), 23-41

This paper studies the role of alternative pension systems that offer collective annuities. The defining characteristic of collective annuities is that they do not depend on an individual’s survival ... [more ▼]

This paper studies the role of alternative pension systems that offer collective annuities. The defining characteristic of collective annuities is that they do not depend on an individual’s survival probabilities. We show that such a system may be welfare improving (with a utilitarian social welfare function) even when private annuity markets are perfect and when life expectancy and earning abilities are positively correlated (i.e., in a setting that is a priori biased against collective annuities). We first concentrate on linear pension systems and contrast two schemes: a pure contributory (Bismarckian) pension and a flat rate (Beveridgean) pension. We show that the case for collective annuities is stronger when they are associated with a flat pension system. Then we analyze nonlinear pension schemes.We show that the solution can be implemented by a pension scheme associated with annuities that reflect some degree of “collectiveness.” Unlike under pure collective annuities, benefits do depend on life expectancy but to a lesser degree than with actuarially fair private annuities. In other words, the impact of survival probabilities is mitigated rather than completely neutralized. [less ▲]

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See detailMathematical Modeling in Wound Healing, Bone Regeneration and Tissue Engineering
Geris, Liesbet ULg; Gerisch, Alf; Schugart, Richard C.

in Acta Biotheoretica (2010), 58(4), 355-367

The processes of wound healing and bone regeneration and problems in tissue engineering have been an active area for mathematical modeling in the last decade. Here we review a selection of recent models ... [more ▼]

The processes of wound healing and bone regeneration and problems in tissue engineering have been an active area for mathematical modeling in the last decade. Here we review a selection of recent models which aim at deriving strategies for improved healing. In wound healing, the models have particularly focused on the inflammatory response in order to improve the healing of chronic wound. For bone regeneration, the mathematical models have been applied to design optimal and new treatment strategies for normal and specific cases of impaired fracture healing. For the field of tissue engineering, we focus on mathematical models that analyze the interplay between cells and their biochemical cues within the scaffold to ensure optimal nutrient transport and maximal tissue production. Finally, we briefly comment on numerical issues arising from simulations of these mathematical models. [less ▲]

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See detailManagement effects on net ecosystem carbon and GHG budgets at European crop sites
Ceschia, E.; Beziat, P.; Dejoux, J. F. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailFormer des enseignants francophones pour de nouveaux publics
Defays, Jean-Marc ULg

in Cadet-Joseph, Lucile; Pellegrini, Florence (Eds.) Situation et perspectives d'évolution des départements d'études française des universités européennes (2010)

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See detailCyprinid herpesvirus 3
Michel, Benjamin; Fournier, Guillaume; Lieffrig, François et al

in Emerging Infectious Diseases (2010), 16

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See detailManagement effects on European cropland respiration
Eugster, W.; Moffat, A. M.; Ceschia, E. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailInterpretation of serum parathyroid hormone concentrations in dialysis patients: what do the KDIGO guidelines change for the clinical laboratory?
Souberbielle, Jean-Claude; Cavalier, Etienne ULg; Jean, Guillaume

in Clinical Chemistry & Laboratory Medicine (2010), 48(6), 769-774

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See detailLa fonction guidage en micromécanique
Merken, Patrick; Debongnie, Jean-François ULg

Book published by DEBONGNIE (JEAN-FRANCOIS) (2010)

1) Modelling the stiffness of a circular notch hinge subjected to flexure, torsion or shear : asymptotic values for a vanishing thickness and correction factors for the general case. 2) Flexible membrane ... [more ▼]

1) Modelling the stiffness of a circular notch hinge subjected to flexure, torsion or shear : asymptotic values for a vanishing thickness and correction factors for the general case. 2) Flexible membrane : stiffness for vanishing radius ratio and correction factor for the general case. 3) Conclusion. 4) Appendices, including a summary of useful formulae. [less ▲]

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See detailTowards calibration and characterization of high-energy beams using charged particle retrodiffusion on a double thin carbon foil system
Chene, Grégoire ULg; Mathis, François ULg; Dupuis, Thomas ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2010), 268(11-12), 2015-2018

The cyclotron of the IPNAS-CEA laboratory of the University of Liege (Belgium) has built a new high-energy, high-resolution beam line based on the use of a pair of 900 bending magnets showing a energy ... [more ▼]

The cyclotron of the IPNAS-CEA laboratory of the University of Liege (Belgium) has built a new high-energy, high-resolution beam line based on the use of a pair of 900 bending magnets showing a energy resolution of Delta E = 1.9 +/- 0.4 keV comparable to that of electrostatic IBA installations. In the 6-20 MeV energy range the contribution of non-Rutherford events to scattering spectra became important and are not very well known. In order to improve our knowledge in that field, a new vacuum chamber especially dedicated to differential cross-section measurements has been constructed. First results obtained with the new set-up are presented. (C) 2010 Elsevier B.V. All rights reserved. [less ▲]

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