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See detailL’édition pour la jeunesse en Belgique francophone : de la nécessité faite vertu à la mondialisation
Habrand, Tanguy ULg

in Pinhas, Luc; Foucault, Jean; Manson, Michel (Eds.) L'édition de jeunesse francophone face à la mondialisation (2010)

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See detailAn Introduction do Differentials with Hyperreal Numbers and Infinite Microscopes
Henry, Valérie ULg

in Problems Ressources, and Issues in Mathematics Undergraduate Studies (2010), 20(1), 39-49

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See detailPrimary diffuse leptomeningeal gliomatosis: an autopsy case and review of the literature
Somja, Joan ULg; Boly, Mélanie ULg; Sadzot, Bernard ULg et al

in Acta Neurologica Belgica (2010), 110(4), 325-33

We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) in a 76-year-old male presenting with confusion, dysarthria, diplopia, lumbal pain and headaches of recent onset. Neurological ... [more ▼]

We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) in a 76-year-old male presenting with confusion, dysarthria, diplopia, lumbal pain and headaches of recent onset. Neurological examination revealed nuchal rigidity and bilateral sixth cranial nerve palsy. The cerebrospinal fluid showed a marked hyperproteinorachia (4711 mg/L) and mild cytorachia (5-10 leucocytes/mm3) with a few atypical lymphoid cells. On admission, brain CT scan and MRI demonstrated diffuse and nodular leptomeningeal contrast enhancement predominant at the skull base and several osteolytic lesions in the right parietal bone. Extensive serological studies for infectious, autoimmune or neoplastic diseases were negative. The work-up diagnosis was neurosarcoidosis or multiple meningeal and osseous metastases of an unknown primary cancer. Surgical biopsy of the right parietal bone lesion showed only fibrous tissue with no evidence of tumour or inflammation. The patient was treated with high dose corticosteroids but its neurological status progressively worsened and he died of aspiration pneumonia 35 days after admission. Post-mortem examination revealed a PDLG, a rare fatal tumour with about 60 cases reported. PDGL is characterized by the diffusion of neoplastic glial cells throughout the leptomeninges without evidence of a primary intra-parenchymal lesion. Recognition of this rare brain tumour is important as recent reports suggest that radiotherapy and chemotherapy can improve patient survival. [less ▲]

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See detailIII-V Devices for Advanced CMOS
Waldron, Niamh; Nguyen, Ngoc Duy ULg; Lin, Dennis et al

in 217th ECS Meeting (2010)

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See detailPierre Alechinsky. Récit d’un itinéraire pictural
Bawin, Julie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2010)

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See detailThe grammaticalization of nominal type noun constructions with kind/sort of: chronology and paths of change
Brems, Lieselotte ULg; Davidse, Kristin

in English Studies (2010), 91

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See detailCentral exclusive production: Vector mesons, dijets, Higgs boson
Cudell, Jean-René ULg

(2010)

I review the situation of theoretical predictions of central exclusive production, and show that the CDF dijet data can be used to constrain the prediction of central exclusive Higgs boson production. I ... [more ▼]

I review the situation of theoretical predictions of central exclusive production, and show that the CDF dijet data can be used to constrain the prediction of central exclusive Higgs boson production. I also show that central exclusive production might be used as a discovery tool for the odderon. [less ▲]

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See detailLe cycle de Guillaume d’Orange ou les Aliscans rajeunis
Henrard, Nadine ULg

in Cazanave, Caroline; Houssais, Yvon (Eds.) Grands textes du Moyen Âge à l'usage des petits (2010)

Examen d'une douzaine de versions de récritures de la geste de Guillaume d'Orange parues entre 1905 et 1995 et destinées à la jeunesse

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See detailLa collection de monnaies islamiques du Musée Bottacin (Padoue): présentation et évaluation
Bauden, Frédéric ULg

in Callegher, Bruno; d'Ottone, Arianna (Eds.) The 2nd Simone Assemani Symposium on Islamic Coins (2010)

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See detail« Objet et contenu – L’intentionnalité husserlienne face à son héritage psychologiste »
Gyemant, Maria ULg

in Studia Phaenomenologica (2010), Vol. X

This paper aims to show how Husserl’s concept of intentionality detaches itself from the background of a thorough and recurrent argument against psychologism. Noting that, primarily, the concept of ... [more ▼]

This paper aims to show how Husserl’s concept of intentionality detaches itself from the background of a thorough and recurrent argument against psychologism. Noting that, primarily, the concept of intentionality was recovered by Brentano’s psychology, it seemed to us important to show how Husserl’s intentionality, as it is conceived in the Logical investigations, distinguishes itself from the “intentional inexistence” that Brentano describes in his Psychology from an empirical standpoint. Showing what parts of this psychology were rejected and what was maintained in Husserl’s theory should be the first concern of those who intend to study the phenomenological concept of intentionality. [less ▲]

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See detailA structural study of the lithiophilite-sicklerite series
Hatert, Frédéric ULg

in 26th European Crystallographic Meeting, Abstract book (2010)

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See detailAnticipatory Artificial Autopoiesis
Dubois, Daniel ULg; Holmberg, Stig C.

in Trappl, Robert (Ed.) CYBERNETICS AND SYSTEMS 2010 (2010)

In examining relationships between autopoiesis and anticipation in artificial life (Alife) systems it is demonstrated that anticipation may increase efficiency and viability in artificial autopoietic ... [more ▼]

In examining relationships between autopoiesis and anticipation in artificial life (Alife) systems it is demonstrated that anticipation may increase efficiency and viability in artificial autopoietic living systems. This paper, firstly, gives a review of the Varela et al [1974] automata algorithm of an autopoietic living cell. Some problems in this algorithm must be corrected. Secondly, a new and original anticipatory artificial autopoiesis algorithm for automata is presented. In our automata system, the asymmetric membrane of the self-creating living cell plays a central role. The simulation confirms the validity of our algorithm in showing its autopoietic properties. [less ▲]

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See detailLes défis du droit romain et du droit privé comparé
Gerkens, Jean-François ULg

in Gosselin, Antoinette; Langevin, Caroline; Wautelet, Patrick (Eds.) L'avenir de la recherche: Réflexions à l'occasion des leçons inaugurales 2010 (2010)

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See detailPET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide.
Nielsen, Carsten H; Kimura, Richard H; WITHOFS, Nadia ULg et al

in Cancer Research (2010), 70(22), 9022-30

Due to the high mortality of lung cancer, there is a critical need to develop diagnostic procedures enabling early detection of the disease while at a curable stage. Targeted molecular imaging builds on ... [more ▼]

Due to the high mortality of lung cancer, there is a critical need to develop diagnostic procedures enabling early detection of the disease while at a curable stage. Targeted molecular imaging builds on the positive attributes of positron emission tomography/computed tomography (PET/CT) to allow for a noninvasive detection and characterization of smaller lung nodules, thus increasing the chances of positive treatment outcome. In this study, we investigate the ability to characterize lung tumors that spontaneously arise in a transgenic mouse model. The tumors are first identified with small animal CT followed by characterization with the use of small animal PET with a novel 64Cu-1,4,7,10-tetra-azacylododecane-N,N',N'',N'''-tetraacetic acid (DOTA)-knottin peptide that targets integrins upregulated during angiogenesis on the tumor associated neovasculature. The imaging results obtained with the knottin peptide are compared with standard 18F-fluorodeoxyglucose (FDG) PET small animal imaging. Lung nodules as small as 3 mm in diameter were successfully identified in the transgenic mice by small animal CT, and both 64Cu-DOTA-knottin 2.5F and FDG were able to differentiate lung nodules from the surrounding tissues. Uptake and retention of the 64Cu-DOTA-knottin 2.5F tracer in the lung tumors combined with a low background in the thorax resulted in a statistically higher tumor to background (normal lung) ratio compared with FDG (6.01+/-0.61 versus 4.36+/-0.68; P<0.05). Ex vivo biodistribution showed 64Cu-DOTA-knottin 2.5F to have a fast renal clearance combined with low nonspecific accumulation in the thorax. Collectively, these results show 64Cu-DOTA-knottin 2.5F to be a promising candidate for clinical translation for earlier detection and improved characterization of lung cancer. [less ▲]

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See detailThe umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood.
Zeddou, Mustapha ULg; Briquet, Alexandra ULg; Relic, Biserka ULg et al

in Cell Biology International (2010), 34(7), 693-701

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these ... [more ▼]

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these cells can be isolated are still under discussion. Whereas BM (bone marrow) is presented as the main source of MSC, despite the invasive procedure related to this source, the possibility of isolating sufficient numbers of these cells from UCB (umbilical cord blood) remains controversial. Here, we present the results of experiments aimed at isolating MSC from UCB, BM and UCM (umbilical cord matrix) using different methods of isolation and various culture media that summarize the main procedures and criteria reported in the literature. Whereas isolation of MSC were successful from BM (10:10) and (UCM) (8:8), only one cord blood sample (1:15) gave rise to MSC using various culture media [DMEM (Dulbecco's modified Eagle's medium) +5% platelet lysate, DMEM+10% FBS (fetal bovine serum), DMEM+10% human UCB serum, MSCGM] and different isolation methods [plastic adherence of total MNC (mononuclear cells), CD3+/CD19+/CD14+/CD38+-depleted MNC and CD133+- or LNGFR+-enriched MNC]. MSC from UCM and BM were able to differentiate into adipocytes, osteocytes and hepatocytes. The expansion potential was highest for MSC from UCM. The two cell populations had CD90+/CD73+/CD105+ phenotype with the additional expression of SSEA4 and LNGFR for BM MSC. These results clearly exclude UCB from the list of MSC sources for clinical use and propose instead UCM as a rich, non-invasive and abundant source of MSC. [less ▲]

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See detailOperational multipartite entanglement classes for symmetric photonic qubit states
Kiesel, N.; Wieczorek, W.; Krins, Stéphanie ULg et al

Poster (2010)

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See detailOptimisatin de la fertilisation azotée des cultures légumières industrielles sous irrigation
Fonder, Nathalie; Heens, Benoit; Xanthoulis, Dimitri ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14(S1), 103-111

Les essais ont été menés sur un projet de quatre ans et ont testé cinq cultures légumières pour optimiser la fertilisation azotée sous irrigation avec des eaux usées. Le site expérimental était localisé ... [more ▼]

Les essais ont été menés sur un projet de quatre ans et ont testé cinq cultures légumières pour optimiser la fertilisation azotée sous irrigation avec des eaux usées. Le site expérimental était localisé dans le périmètre irrigué développé autour de l’usine de production de légumes surgelés, Hesbaye Frost. Dépendant de la rotation effectuée par le fermier, dont une partie du champ était sous expérimentation, quatre cultures légumières ont été testées (épinard, haricot, carotte et fève) ainsi qu’une céréale (froment d’hiver). Suite à la mise en place des essais et aux conditions climatiques, les cultures d’épinard en 1999 et de froment en 2000 n’ont pas testé le facteur irrigation. Les facteurs d’expérimentation étaient trois niveaux de fertilisation azotée différents par rapport à un témoin ne recevant pas d’azote minéral complémentaire et un apport ou non d’eaux usées par irrigation. L’impact de ces facteurs a été mesuré sur les rendements et les reliquats azotés dans le sol après culture. Pour les trois cultures légumières de haricot, carotte et fève qui ont pu être irriguées, les rendements ont toujours été statistiquement supérieurs lorsqu’il y avait un apport d’eau complémentaire par irrigation avec les eaux usées. Le facteur fumure a favorablement amélioré les rendements de l’épinard et du haricot, ainsi que le taux de protéines des céréales. Par contre, les parcelles de carotte et de fève qui n’avaient reçu aucune fumure azotée pendant respectivement trois et quatre années consécutives et qui n’ont pas reçu de fertilisation pour leur culture, n’ont pas donné des rendements statistiquement inférieurs. Le facteur fumure, quel que soit le niveau de fertilisation, n’a pas donné des rendements différents pour ces deux cultures. Les reliquats azotés dans le sol après récolte sont restés acceptables et normaux tant que la fertilisation recommandée n’était pas dépassée ; la fertilisation maximale testée, outrepassant les conseils de fumure raisonnée, a systématiquement laissé des reliquats en azote minéral dans le sol en quantité néfaste pour l’environnement. Ces résidus azotés principalement localisés dans les horizons supérieurs pouvaient être considérés comme récupérables par une culture intermédiaire piège à nitrate (CIPAN), pour autant que cette dernière soit installée dès la fin de l’été, l’automne étant considéré comme trop tardif pour avoir une influence sur la récupération de l’azote. Quel que soit le niveau de fertilisation, les reliquats azotés étaient importants pour la culture de fève par un phénomène de minéralisation en surface, dus aux conditions climatiques et à la charge en azote minéral apporté par les eaux usées utilisées pour l’irrigation. Les reliquats azotés en conditions de non-irrigation sont significativement plus importants que sous irrigation. L’irrigation permet une meilleure solubilisation de l’azote, ce qui facilite son assimilation par la culture en place et réduit les quantités résiduelles dans le sol après récolte. [less ▲]

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See detailIntroduction
Denis, Benoît ULg; Badir, Sémir ULg

in Klinkenberg, Jean-Marie (Ed.) Périphériques Nord. Fragments d'une histoire sociale de la littérature francophone de Belgique (2010)

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See detailEffect of lipopepitdes and iontophoresison acyclovir skin delivery
Nicoli, S.; Eeman, Marc; Deleu, Magali ULg et al

in Journal of Pharmacy & Pharmacology (2010), 62(6), 702-708

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See detailBPCO et inflammation: mise au point d'un groupe d'experts. Les mecanismes de l'inflammation et du remodelage.
Aubier, M.; Marthan, R.; Berger, P. et al

in Revue des Maladies Respiratoires (2010), 27(10), 1254-1266

The present study reviews the literature on inflammation and remodelling mechanisms in chronic obstructive pulmonary disease (COPD). The development of COPD is associated with chronic pulmonary ... [more ▼]

The present study reviews the literature on inflammation and remodelling mechanisms in chronic obstructive pulmonary disease (COPD). The development of COPD is associated with chronic pulmonary inflammation. Immunity (innate or adaptive) plays a role in its onset and continuation. Airways inflammation alters bronchial structure/function relations: increased bronchial wall thickness, increased bronchial smooth muscle tone, seromucosal gland hypersecretion and loss of elastic structures. Circulating markers of pulmonary inflammation indicate its systemic dissemination. Oxidative stress plays a major role in the onset and persistence of tissue abnormalities. The determinants of extra- and intra-cellular redox control are only partially known. Susceptibility genes, antioxidant system insufficiency and reduced levels of anti-age molecules and of histone deacetylation are also involved. The molecular and cellular targets of inflammation and remodelling are numerous and complex. Currently, tools exist to limit inflammation in COPD but not to act on structural remodelling. [less ▲]

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