References of "2010"
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See detailManagement effects on European cropland respiration
Eugster, W.; Moffat, A. M.; Ceschia, E. et al

in Agriculture, Ecosystems & Environment (2010), 139

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See detailFormer des enseignants francophones pour de nouveaux publics
Defays, Jean-Marc ULg

in Cadet-Joseph, Lucile; Pellegrini, Florence (Eds.) Situation et perspectives d'évolution des départements d'études française des universités européennes (2010)

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See detailThe Nociception Coma Scale to assess nociception in disorders of consciousness
Chatelle, Camille ULg; Schnakers, Caroline; VANHAUDENHUYSE, Audrey ULg et al

Poster (2010)

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See detailEEG-based Brain Computer Interface for Locked-In Patients
Chatelle, Camille ULg; Combaz, Adrien

Scientific conference (2010)

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See detailConsciousness in coma and related states
Chatelle, Camille ULg

Conference (2010)

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See detailLa perception de la douleur chez les patients en éveil de coma
Chatelle, Camille ULg

Conference (2010)

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See detailCyprinid herpesvirus 3
Michel, Benjamin; Fournier, Guillaume; Lieffrig, François et al

in Emerging Infectious Diseases (2010), 16

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See detailL’édition pour la jeunesse en Belgique francophone : de la nécessité faite vertu à la mondialisation
Habrand, Tanguy ULg

in Pinhas, Luc; Foucault, Jean; Manson, Michel (Eds.) L'édition de jeunesse francophone face à la mondialisation (2010)

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See detailPresse et littérature africaines durant la période des indépendances : Analyse de la co-influence de deux supports engagés dans la défense d’une cause idéologique
Bassilua Nzuzi, Anicet ULg

in Cahier congolais de communication (2010)

The press and literature have played an important role in the Africa of the independences. They were used as forums through what the intellectual elite expressed its ideological struggle of independence ... [more ▼]

The press and literature have played an important role in the Africa of the independences. They were used as forums through what the intellectual elite expressed its ideological struggle of independence. Sometimes it was found a co-penetration of the two instruments, so that the authors of literature were those that animated the press and vice versa. This co-influence is particularly manifested by a transposition of the usual categories of a support on another. In our study, we examine the different forms that have taken such transfers. [less ▲]

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See detailL'émergence de modèles fonctionnels
Krysinska, Mariza; Schneider-Gilot, Marguerite ULg

Book published by Presses Universitaires de Liège (2010)

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See detailFunctionalization of carbon xerogels for the preparation of Pd/C catalysts by grafting of Pd complex
Diverchy, Chantal; Hermans, Sophie; Job, Nathalie ULg et al

in Studies in Surface Science and Catalysis (2010), 175

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See detailThe vegetative state.
Monti, Martin M; Laureys, Steven ULg; Owen, Adrian M

in BMJ (Clinical Research ed.) (2010), 341

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See detailLes droits de l'homme ne peuvent pas tout résoudre
Frère, Bruno ULg

Article for general public (2010)

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See detailThe zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammals
Tingaud-Sequeira, Angèle; Calusinska, Magdalena ULg; Finn, Roderick N et al

in BMC Evolutionary Biology (2010), 10

Background: Aquaporins are integral membrane proteins that facilitate the transport of water and small solutes across cell membranes. These proteins are vital for maintaining water homeostasis in living ... [more ▼]

Background: Aquaporins are integral membrane proteins that facilitate the transport of water and small solutes across cell membranes. These proteins are vital for maintaining water homeostasis in living organisms. In mammals, thirteen aquaporins (AQP0-12) have been characterized, but in lower vertebrates, such as fish, the diversity, structure and substrate specificity of these membrane channel proteins are largely unknown. Results: The screening and isolation of transcripts from the zebrafish (Danio rerio) genome revealed eighteen sequences structurally related to the four subfamilies of tetrapod aquaporins, i.e., aquaporins (AQP0, -1 and -4), water and glycerol transporters or aquaglyceroporins (Glps; AQP3 and AQP7-10), a water and urea transporter (AQP8), and two unorthodox aquaporins (AQP11 and -12). Phylogenetic analyses of nucleotide and deduced amino acid sequences demonstrated dual paralogy between teleost and human aquaporins. Three of the duplicated zebrafish isoforms have unlinked loci, two have linked loci, while DrAqp8 was found in triplicate across two chromosomes. Genomic sequencing, structural analysis, and maximum likelihood reconstruction, further revealed the presence of a putative pseudogene that displays hybrid exons similar to tetrapod AQP5 and -1. Ectopic expression of the cloned transcripts in Xenopus laevis oocytes demonstrated that zebrafish aquaporins and Glps transport water or water, glycerol and urea, respectively, whereas DrAqp11b and -12 were not functional in oocytes. Contrary to humans and some rodents, intrachromosomal duplicates of zebrafish AQP8 were water and urea permeable, while the genomic duplicate only transported water. All aquaporin transcripts were expressed in adult tissues and found to have divergent expression patterns. In some tissues, however, redundant expression of transcripts encoding two duplicated paralogs seems to occur. Conclusion: The zebrafish genome encodes the largest repertoire of functional vertebrate aquaporins with dual paralogy to human isoforms. Our data reveal an early and specific diversification of these integral membrane proteins at the root of the crown-clade of Teleostei. Despite the increase in gene copy number, zebrafish aquaporins mostly retain the substrate specificity characteristic of the tetrapod counterparts. Based upon the integration of phylogenetic, genomic and functional data we propose a new classification for the piscine aquaporin superfamily. [less ▲]

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