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See detailRecommandations Europeennes 2010 pour le traitement anti-thrombotique de la fibrillation auriculaire: Nouveaux scores pour l'evaluation des risques d'accident vasculaire cerebral et de saignement.
MELON, Pierre ULg; LANCELLOTTI, Patrizio ULg

in Revue Médicale de Liège (2010), 65(10), 580-2

2010 European guidelines for the treatment of atrial fibrillation have introduced modified criteria for the instauration of oral anticoagulation. Guidelines also include a new score for the assessment of ... [more ▼]

2010 European guidelines for the treatment of atrial fibrillation have introduced modified criteria for the instauration of oral anticoagulation. Guidelines also include a new score for the assessment of the risk of bleeding. We report the new risk scores CHA2DS2-VASc and HAS-BLED introduced for the assessment of thrombotic and bleeding risks, respectively. [less ▲]

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See detailCharacteristics of Saturn’s FUV airglow from limb-viewing spectra obtained with Cassini-UVIS
Gustin, Jacques ULg; Stewart, Ian; Gérard, Jean-Claude ULg et al

in Icarus: International Journal of Solar System Studies (2010), 210

This study reports the analysis of far ultraviolet (FUV) limb spectra of the airglow of Saturn in the 1150–1850 Å spectral window, obtained with the Ultraviolet Imaging Spectrograph (UVIS) onboard Cassini ... [more ▼]

This study reports the analysis of far ultraviolet (FUV) limb spectra of the airglow of Saturn in the 1150–1850 Å spectral window, obtained with the Ultraviolet Imaging Spectrograph (UVIS) onboard Cassini, spanning altitudes from 1200 to 4000 km. The FUV limb emission consists of three main contributions: (1) H Ly-a peaking at 1100 km with a brightness of 0.8 kilo-Rayleighs (kR), (2) reflected sunlight longward of 1550 Å which maximizes at 950 km with 16.5 kR and (3) H2 bands in the 1150–1650 Å bandwidth, peaking at 1050 km reaching a maximum of 3.9 kR. A vertical profile of the local H2 volume emission rate has been derived using the hydrocarbon density profiles from a model of the Saturn equatorial atmosphere. It is well matched by a Chapman function, characterized by a maximum value of 3.5 photons cm-3 s-1 in the 800–1650 Å UV bandwidth, peaking at 1020 km. Comparisons between the observed spectra and a first-order synthetic airglow H2 model in the 1150–1650 Å bandwidth show that the spectral shape of the H2 bands is accounted for by solar fluorescence and photoelectron excitation. The best fits are obtained with a combination of H2 fluorescence lines and 20 eV electron impact spectra, the latter contributing 68% of the total H2 airglow emission. [less ▲]

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See detailOn the Recognizability of Self-Generating Sets
Kärki, Tomi; Lacroix, Anne ULg; Rigo, Michel ULg

in Journal of Integer Sequences (2010), 13

Let I be a finite set of integers and F be a finite set of maps of the form n->k_i n + l_i with integer coefficients. For an integer base k>=2, we study the k-recognizability of the minimal set X of ... [more ▼]

Let I be a finite set of integers and F be a finite set of maps of the form n->k_i n + l_i with integer coefficients. For an integer base k>=2, we study the k-recognizability of the minimal set X of integers containing I and satisfying f(X)\subseteq X for all f in F. In particular, solving a conjecture of Allouche, Shallit and Skordev, we show under some technical conditions that if two of the constants k_i are multiplicatively independent, then X is not k-recognizable for any k>=2. [less ▲]

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See detailFluoride PET-CT.
Hustinx, Roland ULg; Beckers, Catherine ULg

in Fanti, Stefano; Farsad, Mohsen; Mansi, Luigi (Eds.) PET-CT Beyond FDG. (2010)

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See detailHearing Preservation in Cochlear Implantation and Drug Treatment.
Barriat, Sébastien ULg; Poirrier, Anne-Lise ULg; Malgrange, Brigitte ULg et al

in Advances in Oto-Rhino-Laryngology (2010), 67

Insertion of an electrode array into the cochlea produces immediate damage to the inner ear, which is responsible for a hearing loss. In addition, a delayed hearing loss can be observed. In order to ... [more ▼]

Insertion of an electrode array into the cochlea produces immediate damage to the inner ear, which is responsible for a hearing loss. In addition, a delayed hearing loss can be observed. In order to maximize hearing preservation after insertion of an electrode and to enhance the performance of the cochlear implant, it has been proposed to deliver pharmacological agents to the inner ear. Molecules can be administered locally to the inner ear through a direct perilymphatic perfusion or through the round window membrane. These modalities of treatment have already been successfully applied to some patients with inner ear diseases. In this paper, we will review some basic aspects of drug delivery to the inner ear to prevent the degeneration of the neurosensory hair cells and auditory neurons, and the actual applicability to humans in order to maintain hearing function after the insertion of electrodes of a cochlear implant. [less ▲]

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See detailIMA Commission on New Minerals, Nomenclature and Classification (CNMNC), Newsletter 5
Williams, Pete; Hatert, Frédéric ULg; Pasero, Marco et al

in Mineralogical Magazine (2010), 74(5), 899-902

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See detailCotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning.
Baron, Frédéric ULg; Lechanteur, Chantal ULg; Willems, Evelyne ULg et al

in Biology of Blood & Marrow Transplantation (2010), 16(6), 838-47

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD ... [more ▼]

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD) after myeloablative allogeneic HCT. This prompted us to investigate in a pilot study whether MSC infusion before HCT could allow nonmyeloablative (NMA) HCT (a transplant strategy based nearly exclusively on graft-versus-tumor effects for tumor eradication) from HLA-mismatched donors to be performed safely. Twenty patients with hematologic malignancies were given MSCs from third party unrelated donors 30-120 minutes before peripheral blood stem cells (PBSCs) from HLA-mismatched unrelated donors, after conditioning with 2 Gy total body irradiation (TBI) and fludarabine. The primary endpoint was safety, defined as a 100-day incidence of nonrelapse mortality (NRM) <35%. One patient had primary graft rejection, whereas the remaining 19 patients had sustained engraftment. The 100-day cumulative incidence of grade II-IV acute GVHD (aGVHD) was 35%, whereas 65% of the patients experienced moderate/severe chronic GVHD (cGVHD). One-year NRM (10%), relapse (30%), overall survival (OS) (80%) and progression-free survival (PFS) (60%), and 1-year incidence of death from GVHD or infection with GVHD (10%) were encouraging. These figures compare favorably with those observed in a historic group of 16 patients given HLA-mismatched PBSCs (but no MSCs) after NMA conditioning, which had a 1-year incidence of NRM of 37% (P = .02), a 1-year incidence of relapse of 25% (NS), a 1-year OS and PFS of 44% (P = .02), and 38% (P = .1), respectively, and a 1-year rate of death from GVHD or infection with GVHD of 31% (P = .04). In conclusion, our data suggest that HLA-mismatched NMA HCT with MSC coinfusion appeared to be safe. [less ▲]

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See detailColoss Working Group 1: monitoring and diagnosis.
Nguyen, Bach Kim ULg; Van der zee, Romée; Vejsnaes, Flemming et al

in Journal of Apicultural Research (2010), 49(1), 97-99

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See detailMolière au théâtre, les Médecins à la Ville
Andrien, Natacha; Jaminon, Martine ULg

Learning material (2010)

Plaquette de l'exposition - Perception de la médecine du 17ème siècle à travers l'oeuvre de Molière

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See detailQui dispose des dispositifs de médiation ?
Servais, Christine ULg

in Questions de Communication (2010), 10

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See detailLe cycle de Guillaume d’Orange ou les Aliscans rajeunis
Henrard, Nadine ULg

in Cazanave, Caroline; Houssais, Yvon (Eds.) Grands textes du Moyen Âge à l'usage des petits (2010)

Examen d'une douzaine de versions de récritures de la geste de Guillaume d'Orange parues entre 1905 et 1995 et destinées à la jeunesse

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See detailBulk organic geochemistry of sediments from Puyehue Lake and its watershed (Chile, 40°S): Implications for paleoenvironmental reconstructions
Bertrand, Sébastien; Sterken, Mieke; Vargas-Ramirez, Lourdes et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (2010), 294

Since the last deglaciation, the mid-latitudes of the southern Hemisphere have undergone considerable environmental changes. In order to better understand the response of continental ecosystems to ... [more ▼]

Since the last deglaciation, the mid-latitudes of the southern Hemisphere have undergone considerable environmental changes. In order to better understand the response of continental ecosystems to paleoclimate changes in southern South America, we investigated the sedimentary record of Puyehue Lake, located in the western piedmont of the Andes in South-Central Chile (40°S). We analyzed the elemental (C, N) and stable isotopic ([delta]13C, [delta]15N) composition of the sedimentary organic matter preserved in the lake and its watershed to estimate the relative changes in the sources of sedimentary organic carbon through space and time. The geochemical signature of the aquatic and terrestrial end-members was determined on samples of lake particulate organic matter (N/C: 0.130) and Holocene paleosols (N/C: 0.069), respectively. A simple mixing equation based on the N/C ratio of these end-members was then used to estimate the fraction of terrestrial carbon ([latin small letter f with hook]T) preserved in the lake sediments. Our approach was validated using surface sediment samples, which show a strong relation between [latin small letter f with hook]T and distance to the main rivers and to the shore. We further applied this equation to an 11.22 m long sediment core to reconstruct paleoenvironmental changes in Puyehue Lake and its watershed during the last 17.9 kyr. Our data provide evidence for a first warming pulse at 17.3 cal kyr BP, which triggered a rapid increase in lake diatom productivity, lagging the start of a similar increase in sea surface temperature (SST) off Chile by 1500 years. This delay is best explained by the presence of a large glacier in the lake watershed, which delayed the response time of the terrestrial proxies and limited the concomitant expansion of the vegetation in the lake watershed (low [latin small letter f with hook]T). A second warming pulse at 12.8 cal kyr BP is inferred from an increase in lake productivity and a major expansion of the vegetation in the lake watershed, demonstrating that the Puyehue glacier had considerably retreated from the watershed. This second warming pulse is synchronous with a 2 °C increase in SST off the coast of Chile, and its timing corresponds to the beginning of the Younger Dryas Chronozone. These results contribute to the mounting evidence that the climate in the mid-latitudes of the southern Hemisphere was warming during the Younger Dryas Chronozone, in agreement with the bipolar see-saw hypothesis. [less ▲]

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See detailPierre Alechinsky. Récit d’un itinéraire pictural
Bawin, Julie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2010)

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See detailA survey of honey bee colony losses in Belgium, fall 2008 to spring 2009
Nguyen, Bach Kim ULg; Mignon, Jacques ULg; Laget, D. et al

Conference (2010)

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See detailPositive impact of compliance to strontium ranelate on the risk of nonvertebral osteoporotic fractures.
Rabenda, Véronique ULg; Reginster, Jean-Yves ULg

in Osteoporosis International (2010), 21(12), 1993-2002

Adherence is now one of the major issues in the management of osteoporosis. This paper relates the relationship existing between adherence to strontium ranelate and the risk of subsequent nonvertebral ... [more ▼]

Adherence is now one of the major issues in the management of osteoporosis. This paper relates the relationship existing between adherence to strontium ranelate and the risk of subsequent nonvertebral fracture among postmenopausal women with osteoporosis. INTRODUCTION: The aim of this study is to investigate compliance to strontium ranelate (SR) therapy and the impact of compliance on the risk of nonvertebral fractures among women with osteoporosis. METHODS: This study was a post-hoc analysis of pooled data from two international, phase III, randomized, placebo-controlled, double-blind studies (the Spinal Osteoporosis Therapeutic Intervention and Treatment Of Peripheral Osteoporosis). A nested case-control study was performed in the strontium ranelate-treated population. Compliance was quantified using the medication possession ratio (MPR). RESULTS: Two hundred eighty-five nonvertebral fracture cases (hip fx n = 70; major nonvertebral fx n = 213) were identified and matched to 1,425 controls. The mean MPR was 86.8% for controls and 82.6% for cases (p < 0.001). Women who were compliant to SR had a 38% reduction in all nonvertebral fractures compared with those who were not (OR = 0.62; 95%CI[0.47-0.81; p < 0.001). Considering hip fractures only, the risk was reduced by 50% for compliant patients compared to noncompliant patients (OR = 0.50; 95%CI[0.28-0.88]; p < 0.05). CONCLUSION: Our analyses emphasize the importance of good compliance to treatment in order to reduce the risk of osteoporotic fractures. In particular, there was a greater reduction in the risk of nonvertebral and hip fractures with increase compliance. [less ▲]

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See detailTravaux pratiques de microbiologie générale
HAYETTE, Marie-Pierre ULg; HUYNEN, Pascale ULg; MEEX, Cécile ULg

Learning material (2010)

Le syllabus reprend les méthodologies utilisées pour l'étude des bactéries, levures, virus. Il décrit les réactions sérologiques et les principes de biologie moléculaire appliqués au diagnostic ... [more ▼]

Le syllabus reprend les méthodologies utilisées pour l'étude des bactéries, levures, virus. Il décrit les réactions sérologiques et les principes de biologie moléculaire appliqués au diagnostic microbiologique. [less ▲]

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See detailL'architecture, producteur de "lien social' ou acteur dans les "luttes sociales"?
Brausch, Géraldine ULg

in Dassonville, Chantal; Cohen, Maurizio (Eds.) Architecture, Wallonie-Bruxelles. Inventaire #0 Inventories 2005-2010 (2010)

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See detailComparison of mechanical efficiency of two microstructures of Ti5553 alloy in the case of bolted flanges submitted to tensile loading
Van Hoof, T.; Ben Bettaieb, Mohamed ULg; Lani, F. et al

in Steel Research International (2010), 81(9), 1148-1152

A combination of numerical and experimental methods is used to compare the efficiency of two microstructures of Ti5553 titanium alloy in an industrial test case. The test case consists in two parts of ... [more ▼]

A combination of numerical and experimental methods is used to compare the efficiency of two microstructures of Ti5553 titanium alloy in an industrial test case. The test case consists in two parts of sectors of aircraft engine stators linked together by an Inconel bolt and submitted to tensile loading. The efficiency of these microstructures is evaluated by using finite element (FE) models. The chosen FE models take into account elasto-visco-plastic material behaviors, contact with friction (bolt heads/flanges and flange/flange), and the initial bolt tightening. The parameters of the elasto-visco-plastic (EVP) material law are adjusted from experimental results extracted from tensile tests performed on Inconel, and Ti5553 alloys. Viscous properties are observed at different strain rates. The studied alloy is assumed to be plastically isotropic. In order to compare the fracture resistance of both microstructures, a micro-mechanical (damage based) rupture model ([4]) is used as a FE post-processing step. [less ▲]

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See detailEffect of Benchmark Misspecification on Risk-Adjusted Performance Measures
Bodson, Laurent ULg; Hübner, Georges ULg

in Gregoriou, Greg N.; Hoppe, Christian; Wehn, Carsten (Eds.) The Risk Modeling Evaluation Handbook (2010)

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