References of "2010"
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See detailEnseigner la biologie en premier BAC sciences dans le cadre du projet 123...Sciences
Thiry, Marc ULg

Diverse speeche and writing (2010)

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See detailCurrent approaches to phylogenomic reconstruction
Baurain, Denis ULg; Philippe, Hervé

in Caetano-Anollés, Gustavo (Ed.) Evolutionary Genomics and Systems Biology (2010)

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See detailFormación de compuestos raciales de maíz precoz (Zea mays L.) para comunidades altas de Cusco
Cosio, Pompeyo; Catalán, Wilfredo; Baudoin, Jean-Pierre ULg

in Primer Congreso Peruano de Mejoramiento Genético y Biotecnología Agricola (2010)

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See detailThe therapeutic potential of TNF-alpha antagonists for skin psoriasis comorbidities.
Pierard, Gérald ULg; Pierard, Claudine ULg; Szepetiuk, Grégory ULg et al

in Expert Opinion on Biological Therapy (2010), 10(8), 1197-208

IMPORTANCE OF THE FIELD: Alopecia, psoriatic arthritis, the metabolic syndrome, inflammatory bowel diseases and cardiovascular diseases may occur as skin psoriatic comorbidities. TNF-alpha antagonists are ... [more ▼]

IMPORTANCE OF THE FIELD: Alopecia, psoriatic arthritis, the metabolic syndrome, inflammatory bowel diseases and cardiovascular diseases may occur as skin psoriatic comorbidities. TNF-alpha antagonists are used to treat psoriasis. Adalimumab is one of the recognized active agents for this indication. AREAS COVERED IN THIS REVIEW: The current peer-reviewed publications and presentation of original findings. WHAT THE READER WILL GAIN: Adalimumab is active on recalcitrant psoriasis and some of its comorbidities, particularly arthropathies and Crohn's disease. However, the progression of the radiological alterations is limited with regression of the bony erosions. Psoriatic enthesopathy also regresses. Mortality associated with psoriasis arthropathy is on the decline. Crohn's disease, the most frequent inflammatory bowel comorbidity of psoriasis, is responsive to adalimumab. The effect of adalimumab on the metabolic syndrome and cardiovascular involvement is more erratic. The spectacular effects of adalimumab may be associated with some adverse effects. In particular, despite a marked reduction in the psoriasis area-and-severity index (PASI) score some new acute lesions of cutaneous psoriasis may develop corresponding to paradoxical psoriasis. Other potential adverse effects include infections, granulomas, rapid growth of cancers and occurrence of lymphomas. TAKE HOME MESSAGE: Adalimumab frequently controls moderate-to-severe forms of cutaneous psoriasis and some of its comorbidities. [less ▲]

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See detailReduction du risque metabolique associe a l'obesite en modulant l'exposition tissulaire au cortisol.
Iovino, Alessandra ULg; Paquot, Nicolas ULg; Scheen, André ULg

in Revue Médicale Suisse (2010), 6(260), 1608-12

The 11-beta-hydroxysteroid dehydrogenase type 1 (11HSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the liver and the adipose tissue. It may play a role in the ... [more ▼]

The 11-beta-hydroxysteroid dehydrogenase type 1 (11HSD1) enzyme promotes the local conversion from cortisone to cortisol, especially in the liver and the adipose tissue. It may play a role in the pathophysiology of abdominal obesity and the metabolic syndrome, both showing some similarities with the Cushing syndrome. Considering experimental results obtained in rodents, the inhibition of this enzyme could exert favourable metabolic effects, with significant reductions in plasma glucose, insulin resistance and dyslipidaemia. Synthetic inhibitors of 11HSD1 are currently in development with encouraging preliminary results, first in animals, and more recently in humans. Selective inhibitors of 11HSD1 may represent an innovative approach in the pharmacological management of obesity, metabolic syndrome and type 2 diabetes in a near future. [less ▲]

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See detailRegain d'intérêt pour la Kétamine
Marchant, Nicolas; Joris, Jean ULg

in Revue Médicale de Liège (2010), 65(1), 29-34

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See detailSelective epitaxial growth of III-V semiconductor on large-area Si substrate for advanced logic CMOS technologies
Nguyen, Ngoc Duy ULg; Brammertz, Guy; Wang, Gang et al

Conference (2010)

The continued downscaling of the metal-oxide semiconductor (MOS) transistor for sub-22 nm logic circuits with boosted performance will require the introduction of new channel materials with carrier ... [more ▼]

The continued downscaling of the metal-oxide semiconductor (MOS) transistor for sub-22 nm logic circuits with boosted performance will require the introduction of new channel materials with carrier mobility higher than that of Si, such as Ge for pMOS. The use of III-V compounds for nMOS devices poses however additional challenges related to the hetero-epitaxial growth of a polar semiconductor on a non-polar surface. Furthermore, these high-mobility materials have to be fabricated on large-area Si substrates, in the perspective of application in a standard low-cost very-large-scale integration scheme. In this work, we report on the successful growth of GaAs on 200 mm Si wafers by means of metal-organic vapor deposition using a modified Crius Close-Coupled Showerhead system from AIXTRON AG. We used Si (100) wafers with off-axis orientation (6° miscut towards <111>) in order to avoid the formation of anti-phase domains which lead to Ga-Ga and As-As bonds at their boundaries that have strong detrimental effects on the electrical conduction. In our approach, based on Ge virtual substrates with low threading dislocation (TD) density, the lattice mismatch between Si and GaAs is accommodated and, thus, no additional TD is introduced in the deposited III-V film. Our results show that smooth GaAs layers can be epitaxially grown on large-area Si substrates with high wafer-scale thickness uniformity. The excellent quality of the deposited GaAs was confirmed by photoluminescence and electron microscopy. Our process also demonstrates very high selectivity on patterned wafers with SiO2 mask and enabled the fabrication of capacitor structures using an integration process flow very similar to standard high volume Si manufacturing lines. The capacitance-voltage characteristics were similar to the ones obtained on a bulk GaAs substrate, and showed extremely tight within-wafer and wafer-to-wafer distributions as is standard to Si manufacturing. [less ▲]

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See detailModes et formes d'émergence d'une nouvelle génération
Delhalle, Nancy ULg

in Ubu: scènes d'Europe = European stages (2010)

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See detailIron-manganese phosphates with the olivine- and alluaudite-type structures: crystal chemistry and applications
Hatert, Frédéric ULg

in Minerals as Advanced Materials II, Abstract Book (2010)

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See detailStress Doppler echocardiography in valvular heart diseases: utility and assessment.
O'Connor, Kim; LANCELLOTTI, Patrizio ULg; Pierard, Luc ULg

in Future Cardiology (2010), 6(5), 611-25

This article is a review on the role of stress echocardiography in valvular heart diseases, describing what the validated indications are, how to perform the test and the utility of performing this ... [more ▼]

This article is a review on the role of stress echocardiography in valvular heart diseases, describing what the validated indications are, how to perform the test and the utility of performing this examination. Most valve diseases are characteristically dynamic and this dynamic component is best appreciated by exercise Doppler echocardiography. Dobutamine stress echocardiography is also useful in patients with severe aortic stenosis and left ventricular dysfunction. The main advantage of stress echocardiography is to concomitantly allow the evaluation of symptoms, exercise capacity and the hemodynamic consequences of valve diseases, especially in patients with severe valve diseases who deny symptoms or present equivocal symptoms. It also provides important prognostic information and may help to optimize surgical timing in difficult cases. Whether these data should be integrated in the management of patients needs further validation. [less ▲]

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See detailServices de soins et services à domicile en Belgique - Inventaire des activités de soin et d'aide chez les infirmières et aides-soignantes
Heyden, Isabelle ULg; Tancredi; Gosset, Christiane ULg

in Revue d'Epidémiologie et de Santé Publique = Epidemiology and Public Health (2010), S58

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See detailAn Introduction do Differentials with Hyperreal Numbers and Infinite Microscopes
Henry, Valérie ULg

in Problems Ressources, and Issues in Mathematics Undergraduate Studies (2010), 20(1), 39-49

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See detailPortfolio professionnel : Projet personnel :Enseignement de la nutrition en médecine vétérinaire : un projet d'exercices en ligne visant à susciter l'apprentissage pré-clinique et l'autonomie
Diez, Marianne ULg

Learning material (2010)

Portfolio présentant l'enseignement et une innovation pédagogique sous forme de 2 articles

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See detailChorea associated with anti-phospholipid antibodies: case report.
DEMONTY, Jean ULg; GONCE, Michel ULg; Ribai, P. et al

in Acta clinica Belgica (2010), 65(5), 350-3

A seventeen year-old boy developed left sided chorea in a few days, subsequently involving the four limbs. Although he presented a marfanoid phenotype, genetic analysis of the Fibrillin 1 was normal. The ... [more ▼]

A seventeen year-old boy developed left sided chorea in a few days, subsequently involving the four limbs. Although he presented a marfanoid phenotype, genetic analysis of the Fibrillin 1 was normal. The genes for familial chorea and Huntington's disease were also negative. Biological tests showed normal serum homocystein, but revealed very high levels of anti-beta2-GP1 IgG, anticardiolipin and lupus anticoagulant, which remained at similar values for a period of over three months. Electroencephalogram and cerebral magnetic resonance imaging (MRI) showed no abnormalities. Brain PET-scan disclosed bilateral striatal hypermetabolism. The patient was treated with methylprednisolone and low dose of acetylsalicylic acid. He improved markedly after six weeks of treatment, and choreic movements disappeared completely after two months. A control PET-scan performed at this time showed reversion of striated hypermetabolism to a normal pattern. The pathogenic aspects of this relatively rare case of chorea are discussed. [less ▲]

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See detailThe umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood.
Zeddou, Mustapha ULg; Briquet, Alexandra ULg; Relic, Biserka ULg et al

in Cell Biology International (2010), 34(7), 693-701

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these ... [more ▼]

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these cells can be isolated are still under discussion. Whereas BM (bone marrow) is presented as the main source of MSC, despite the invasive procedure related to this source, the possibility of isolating sufficient numbers of these cells from UCB (umbilical cord blood) remains controversial. Here, we present the results of experiments aimed at isolating MSC from UCB, BM and UCM (umbilical cord matrix) using different methods of isolation and various culture media that summarize the main procedures and criteria reported in the literature. Whereas isolation of MSC were successful from BM (10:10) and (UCM) (8:8), only one cord blood sample (1:15) gave rise to MSC using various culture media [DMEM (Dulbecco's modified Eagle's medium) +5% platelet lysate, DMEM+10% FBS (fetal bovine serum), DMEM+10% human UCB serum, MSCGM] and different isolation methods [plastic adherence of total MNC (mononuclear cells), CD3+/CD19+/CD14+/CD38+-depleted MNC and CD133+- or LNGFR+-enriched MNC]. MSC from UCM and BM were able to differentiate into adipocytes, osteocytes and hepatocytes. The expansion potential was highest for MSC from UCM. The two cell populations had CD90+/CD73+/CD105+ phenotype with the additional expression of SSEA4 and LNGFR for BM MSC. These results clearly exclude UCB from the list of MSC sources for clinical use and propose instead UCM as a rich, non-invasive and abundant source of MSC. [less ▲]

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See detailLa collection de monnaies islamiques du Musée Bottacin (Padoue): présentation et évaluation
Bauden, Frédéric ULg

in Callegher, Bruno; d'Ottone, Arianna (Eds.) The 2nd Simone Assemani Symposium on Islamic Coins (2010)

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See detailEffect of GammaRay in the Progeny of Trispecific Hybrid [(Gossypium hirsutum x G. raimondii)² x G. sturtianum]
Diouf, Fatimata Bintou Hassédine ULg; Benbouza, H; Konan, O et al

in Notulae Botanicae Horti Agrobotanici Cluj-Napoca (2010), 38

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