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See detailcarnet de pédiatrie en Afrique: l'examen neurologique du nouveau-né
Battisti, Oreste ULg

Learning material (2010)

le cours discute des modalité de l'examen neurologique du nouveau-né en revoyant le concept de Dubowitz, le concept de Prechtl, le concept de Brazelton.

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See detail"Du Rwanda au Coeur des Ténèbres. Jean-Philippe Stassen illustre Conrad"
Demoulin, Laurent ULg

E-print/Working paper (2010)

Dans sa façon d'illustrer Coeur des ténèbres de Conrad, le dessinateur de bande dessinée Jean-Philippe Stassen interprète de façon très personnelle l'oeuvre du romancier. La bande dessinée se déclare ici ... [more ▼]

Dans sa façon d'illustrer Coeur des ténèbres de Conrad, le dessinateur de bande dessinée Jean-Philippe Stassen interprète de façon très personnelle l'oeuvre du romancier. La bande dessinée se déclare ici aussi légitime que la littérature. [less ▲]

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See detailCotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning.
Baron, Frédéric ULg; Lechanteur, Chantal ULg; Willems, Evelyne ULg et al

in Biology of Blood & Marrow Transplantation (2010), 16(6), 838-47

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD ... [more ▼]

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD) after myeloablative allogeneic HCT. This prompted us to investigate in a pilot study whether MSC infusion before HCT could allow nonmyeloablative (NMA) HCT (a transplant strategy based nearly exclusively on graft-versus-tumor effects for tumor eradication) from HLA-mismatched donors to be performed safely. Twenty patients with hematologic malignancies were given MSCs from third party unrelated donors 30-120 minutes before peripheral blood stem cells (PBSCs) from HLA-mismatched unrelated donors, after conditioning with 2 Gy total body irradiation (TBI) and fludarabine. The primary endpoint was safety, defined as a 100-day incidence of nonrelapse mortality (NRM) <35%. One patient had primary graft rejection, whereas the remaining 19 patients had sustained engraftment. The 100-day cumulative incidence of grade II-IV acute GVHD (aGVHD) was 35%, whereas 65% of the patients experienced moderate/severe chronic GVHD (cGVHD). One-year NRM (10%), relapse (30%), overall survival (OS) (80%) and progression-free survival (PFS) (60%), and 1-year incidence of death from GVHD or infection with GVHD (10%) were encouraging. These figures compare favorably with those observed in a historic group of 16 patients given HLA-mismatched PBSCs (but no MSCs) after NMA conditioning, which had a 1-year incidence of NRM of 37% (P = .02), a 1-year incidence of relapse of 25% (NS), a 1-year OS and PFS of 44% (P = .02), and 38% (P = .1), respectively, and a 1-year rate of death from GVHD or infection with GVHD of 31% (P = .04). In conclusion, our data suggest that HLA-mismatched NMA HCT with MSC coinfusion appeared to be safe. [less ▲]

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See detailQui dispose des dispositifs de médiation ?
Servais, Christine ULg

in Questions de Communication (2010), 10

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See detailLe cycle de Guillaume d’Orange ou les Aliscans rajeunis
Henrard, Nadine ULg

in Cazanave, Caroline; Houssais, Yvon (Eds.) Grands textes du Moyen Âge à l'usage des petits (2010)

Examen d'une douzaine de versions de récritures de la geste de Guillaume d'Orange parues entre 1905 et 1995 et destinées à la jeunesse

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See detailJean-Philippe Toussaint
Demoulin, Laurent ULg; Piret, Pierre

in Textyles : Revue des Lettres Belges de Langue Française (2010), 38

L'œuvre de Jean-Philippe Toussaint n'a à ce jour donné lieu à aucune publication monographique en français. Textyles a voulu remédier à cette lacune, en mettant en chantier un numéro pionnier et, à ce ... [more ▼]

L'œuvre de Jean-Philippe Toussaint n'a à ce jour donné lieu à aucune publication monographique en français. Textyles a voulu remédier à cette lacune, en mettant en chantier un numéro pionnier et, à ce titre, résolument ouvert : mettre en perspective les différentes facettes de l’œuvre en multipliant les angles d’approche, tel fut l’objectif qui présida à l’élaboration du présent dossier. Spécialistes des études littéraires, du cinéma et de la photographie s’y côtoient, qui développent des analyses s’attachant à dégager les modes de composition et les principales caractéristiques esthétiques de l’œuvre, à montrer comment elle radiographie les discours contemporains et à la situer dans l’histoire de la littérature. [less ▲]

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See detailPierre Alechinsky. Récit d’un itinéraire pictural
Bawin, Julie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2010)

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See detailLouvre-Lens : Le Louvre autrement : des coulisses aux expositions
Bodéré, Audrey; Drouguet, Noémie ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2010), 5

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See detailPyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation.
Mortier, Jeremie; Frederick, Raphael; Ganeff, Corinne et al

in Biochemical Pharmacology (2010), 79(10), 1462-72

In this work, we aimed to build a 3D-model of NIK and to study the binding of pyrazolo[4,3-c]isoquinolines with a view to highlight the structural elements responsible for their inhibitory potency ... [more ▼]

In this work, we aimed to build a 3D-model of NIK and to study the binding of pyrazolo[4,3-c]isoquinolines with a view to highlight the structural elements responsible for their inhibitory potency. However, in the course of this work, we unexpectedly found that the pyrazolo[4,3-c]isoquinolines initially reported as NIK inhibitors were neither inhibitors of this enzyme nor of the alternative NF-kappaB pathway, but were in fact inhibitors of another kinase, the TGF-beta activated kinase 1 (TAK1) which is involved in the classical NF-kappaB pathway. [less ▲]

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See detailA survey of honey bee colony losses in Belgium, fall 2008 to spring 2009
Nguyen, Bach Kim ULg; Mignon, Jacques ULg; Laget, D. et al

Conference (2010)

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See detailIMA Commission on New Minerals, Nomenclature and Classification (CNMNC), Newsletter 3
Williams, Pete; Hatert, Frédéric ULg; Pasero, Marco et al

in Mineralogical Magazine (2010), 74

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See detailFollicular fluids, immunological fingerprint and infertility
Lédée, N; Munaut, Carine ULg; PERRIER d'HAUTERIVE, Sophie ULg et al

Conference (2010)

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See detailMaternal plasma soluble endoglin at 11-13 weeks's gestation in pre-eclampsia
Foidart, Jean-Michel ULg; Munaut, Carine ULg; Chantraine, Frédéric ULg et al

in Ultrasound in Obstetrics & Gynecology (2010), 35(6), 680-7

Objectives: To examine the performance of screening for preeclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein A (PAPP-A), placental growth ... [more ▼]

Objectives: To examine the performance of screening for preeclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein A (PAPP-A), placental growth factor (PlGF) and uterine artery lowest pulsatibility index (L-PI) at 11-13 weeks of gestation. Methods: Uterine artery L-PI, sEng, PAPP-A and PlGF were measured at 11-13 weeks in 90 singleton pregnancies that subsequently developed PE, including 30 that required delivery before 34 weeks (early-PE) and 60 with late-PE, and 180 unaffected controls. Screening performance for PE by maternal factors, sEng, PAPP-A, PlGF and uterine artery L-PI and their combinations was determined. Results: In early-PE, compared to controls, plasma sEng and uterine L-PI were significantly increased and serum PAPP-A and PlGF were decreased. In late-PE, compared to controls, serum PlGF was decreased and uterine L-PI was increased but plasma sEng and serum PAPP-A were not significantly different. In screening for early-PE, the detection rate at a 10% false positive rate was 46.7% for sEng alone and 96.3% for a combination of maternal factors, sEng, PlGF and uterine artery L-PI. Conclusions: Effective screening for early-PE can be provided by a combination of maternal factors, sEng, PlGF and uterine artery L-PI at 11-13 weeks. [less ▲]

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See detailIntroduction
Drouguet, Noémie ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2010), 5

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