References of "2010"
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See detail"Le droit des biens : une évolution indispensable sans révolution inutile"
Lecocq, Pascale ULg; Vanbrabant, Bernard ULg

in L'avenir de la recherche, Réflexions à l'occasion des leçons inaugurales 2010 (2010)

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See detailColonisation credit in recent wet heathland butterfly communities
Cristofoli, Sara ULg; Mahy, Grégory ULg

in Insect Conservation and Diversity (2010), 3

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See detailL’extraction des huiles essentielles par micro-ondes : Quels avantages ?
Ramdani, M.; Benchat, N.; Amhamdi, H. et al

Poster (2010)

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See detailGroup theoretical study of nonstrange and strange mixed symmetric baryon states [Nc-1,1] in the 1/Nc expansion
Matagne, Nicolas; Stancu, Floarea ULg

in Physical Review. D : Particles and Fields (2010), 81

Using group theory arguments we extend and complete our previous work by deriving all SU(6) exact wave functions associated with the spectrum of mixed symmetric baryon states [Nc-1,1] in the 1/Nc ... [more ▼]

Using group theory arguments we extend and complete our previous work by deriving all SU(6) exact wave functions associated with the spectrum of mixed symmetric baryon states [Nc-1,1] in the 1/Nc expansion. The extension to SU(6) enables us to study the mass spectra of both strange and nonstrange baryons, while previous work was restricted to nonstrange baryons described by SU(4). The wave functions are specially written in a form to allow a comparison with the approximate, customarily used wave functions, where the system is separated into a ground state core and an excited quark. We show that the matrix elements of the flavor operator calculated with the exact wave functions acquire the same asymptotic form at large Nc, irrespective of the spin-flavor multiplet contained in [Nc-1,1], while with the approximate wave function one cannot obtain a similar behavior. The isoscalar factors of the permutation group of Nc particles derived here can be used in any problem where a given fermion system is described by the partition [Nc-1,1], and one fermion has to be separated from the rest. [less ▲]

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See detailBiomolecules in multilayer film for antimicrobial and easy-cleaning stainless steel surface applications
Vreuls, Christelle ULg; Zocchi, Germaine ULg; Garitte, Geoffrey ULg et al

in Biofouling (2010), 26(6), 645-656

Microorganisms are able to attach to, grow on, and ultimately form biofilms on a large variety of surfaces, such as industrial equipment, food contact surfaces, medical implants, prostheses and operating ... [more ▼]

Microorganisms are able to attach to, grow on, and ultimately form biofilms on a large variety of surfaces, such as industrial equipment, food contact surfaces, medical implants, prostheses and operating rooms. Once organized into biofilms, bacteria are difficult to remove and kill, which increases the risk of cross-contamination and infection. One way to address the problem may thus be to develop antibacterial, anti-adhesion, ‘easy cleaning’ surfaces. In this study, stainless steel (SS) surfaces with antibacterial properties were created by embedding several antimicrobial peptides in a multilayer film architecture. The biocidal effect of these surfaces was demonstrated against both Gram-positive and Gram-negative bacteria according to two ISO tests. Also, coating SS surfaces with either mucin or heparin led to a reduction of <i>S. epidermidis</i> adhesion of almost 95% <i>vs</i> the bare substratum. Finally, by combining both antibacterial and anti-adhesion biomolecules in the same multilayer film, SS surfaces with better cleanability were produced. This surface coating property may help to delay the buildup of a dead bacterial layer which is known to progressively reduce exposure of the coating, leading to an undesirable decrease in the antibacterial effect of the surface. [less ▲]

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See detailCarbonate chemistry in the coastal zone responds more strongly to eutrophication than to ocean acidification
Borges, Alberto ULg; Gypens, N.

in Limnology & Oceanography (2010), 55(1), 346-353

The accumulation of anthropogenic CO2 in the ocean has altered carbonate chemistry in surface waters since preindustrial times and is expected to continue to do so in the coming centuries. Changes in ... [more ▼]

The accumulation of anthropogenic CO2 in the ocean has altered carbonate chemistry in surface waters since preindustrial times and is expected to continue to do so in the coming centuries. Changes in carbonate chemistry can modify the rates and fates of marine primary production and calcification. These modifications can in turn lead to feedback on increasing atmospheric CO2. We show, using a numerical model, that in highly productive nearshore coastal marine environments, the effect of eutrophication on carbon cycling can counter the effect of ocean acidification on the carbonate chemistry of surface waters. Also, changes in river nutrient delivery due to management regulation policies can lead to stronger changes in carbonate chemistry than ocean acidification. Whether antagonistic or synergistic, the response of carbonate chemistry to changes of nutrient delivery to the coastal zone (increase or decrease, respectively) is stronger than ocean acidification. [less ▲]

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See detailInfection models for dermatophytes research
Mignon, Bernard ULg

Conference (2010)

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See detailDummy run and conformity indices in the ongoing EORTC low-grade glioma trial 22033-26033: First evaluation of quality of radiotherapy planning
Musat, E.; Roelofs, E.; Bar-Deroma, R. et al

in Radiotherapy & Oncology (2010), 95(2), 218-224

Purpose: Early assessment of radiotherapy (RT) quality in the ongoing EORTC trial comparing primary temozolomide versus RT in low-grade gliomas. Materials and methods: RT plans provided for dummy cases ... [more ▼]

Purpose: Early assessment of radiotherapy (RT) quality in the ongoing EORTC trial comparing primary temozolomide versus RT in low-grade gliomas. Materials and methods: RT plans provided for dummy cases were evaluated and compared against expert plans. We analysed: (1) tumour and organs-at-risk delineation, (2) geometric and dosimetric characteristics, (3) planning parameters, compliance with dose prescription and Dmax for OAR (4) indices: RTOG conformity index (CI), coverage factor (CF), tissue protection factor (PF); conformity number (CN = PF× CF); dose homogeneity in PTV (U). Results: Forty-one RT plans were evaluated. Only two (5%) centres were requested to repeat CTV-PTV delineations. Three (7%) plans had a significant under-dosage and dose homogeneity in one deviated > 10%. Dose distribution was good with mean values of 1.5, 1, 0.68, and 0.68 (ideal values = 1) for CI, CF, PF, and CN, respectively. CI and CN strongly correlated with PF and they correlated with PTV. Planning with more beams seems to increase PTV Dmin, improving CF. U correlated with PTV Dmax. Conclusion: Preliminary results of the dummy run procedure indicate that most centres conformed to protocol requirements. To quantify plan quality we recommend systematic calculation of U and either CI or CN, both of which measure the amount of irradiated normal brain tissue. © 2010 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailCost-Effectiveness of Osteoporosis Screening Followed by Treatment: The Impact of Medication Adherence.
Hiligsmann, Mickaël ULg; Gathon, Henry-Jean ULg; Bruyère, Olivier ULg et al

in Value in Health (2010), 13(4), 394-401

ABSTRACT Objective: To estimate the impact of medication adherence on the cost-effectiveness of mass-screening by bone densitometry followed by alendronate therapy for women diagnosed with osteoporosis ... [more ▼]

ABSTRACT Objective: To estimate the impact of medication adherence on the cost-effectiveness of mass-screening by bone densitometry followed by alendronate therapy for women diagnosed with osteoporosis. Methods: A validated Markov microsimulation model with a Belgian health-care payer perspective and a lifetime horizon was used to assess the cost per quality-adjusted life year (QALY) gained of the screening/treatment strategy compared with no intervention. Real-world adherence to alendronate therapy and full adherence over 5 years were both investigated. The real-world adherence scenario employed adherence data from published observational studies, and medication adherence was divided into persistence, compliance, and primary adherence. Uncertainty was investigated using one-way and probabilistic sensitivity analyses. Results: At 65 years of age, the costs per QALY gained because of the screening/treatment strategy versus no intervention are euro32,008 and euro16,918 in the real-world adherence and full adherence scenarios, respectively. The equivalent values are euro80,836 and euro40,462 at the age of 55 years, and they decrease to euro10,600 and euro1229 at the age of 75 years. Sensitivity analyses show that the presence of the upfront cost of case finding has a substantial role in the impact of medication adherence on cost-effectiveness. Conclusion: This study indicates that nonadherence with osteoporosis medications substantially increases the incremental cost-effectiveness ratio of osteoporosis screening strategies. All aspects of medication adherence (i.e., compliance, persistence, and primary adherence) should therefore be reported and included in pharmacoeconomic analyses, and especially in the presence of the upfront cost of case finding (such as screening cost). [less ▲]

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See detailDevelopment of lead-210 measurement in peat using polonium extraction. A procedural comparison
De Vleeschouwer, François; Sikorski, Jarek; Fagel, Nathalie ULg

in Geochronometria (2010)

Two chemical treatments for lead-210 measurement were compared on the sub-surface samples of a core from an ombrotrophic bog from East Belgium. The classical procedure involves a concentrated acid ... [more ▼]

Two chemical treatments for lead-210 measurement were compared on the sub-surface samples of a core from an ombrotrophic bog from East Belgium. The classical procedure involves a concentrated acid extraction of polonium. However, this treatment represents substantial health risks together with unknowns regarding both the degree of cleanliness and the Po extraction rate, and most importantly, is rather time consuming. We developed here an improved procedure involving an ashing step prior to acid extraction. This allows substantial improvements such as: 1/ the use of a relatively small amount of acid compared to the classical procedure and 2/ the substantial reduction of a total sample digestion time. Measurements of 210Pb concentrations were conducted by alpha spectrometry. Results show a good agreement of unsupported 210Pb activity obtained for both procedures, although some unknowns remain concerning the adsorption of 210Po on the plastic test tube, the volatilization of a small amount of ash, or the absorption of alpha particle at the alpha source surface. This however should not affect the 210Pb measurement as all the samples are spiked prior to ashing (i.e. the recoveries are fully monitored). Through this study, we are suggesting researchers to follow this new procedure in order to increase safety, cleanliness, better recovery and substantial time gain. [less ▲]

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See detailHigher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.
El Hour, Mehdi ULg; Moncada-Pazos, A.; Blacher, Silvia ULg et al

in Oncogene (2010), 29(20), 3025-32

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in ... [more ▼]

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in tissue remodeling and angiogenesis associated with physiological and pathological processes. To elucidate the in vivo functions of ADAMTS-12, we have generated a knockout mouse strain (Adamts12−/−) in which Adamts12 gene was deleted. The mutant mice had normal gestations and no apparent defects in growth, life span and fertility. By applying three different in vivo models of angiogenesis (malignant keratinocyte transplantation, Matrigel plug and aortic ring assays) to Adamts12−/− mice, we provide evidence for a protective effect of this host enzyme toward angiogenesis and cancer progression. In the absence of Adamts-12, both the angiogenic response and tumor invasion into host tissue were increased. Complementing results were obtained by using medium conditioned by cells overexpressing human ADAMTS-12, which inhibited vessel outgrowth in the aortic ring assay. This angioinhibitory effect of ADAMTS-12 was independent of its enzymatic activity as a mutated inactive form of the enzyme was similarly efficient in inhibiting endothelial cell sprouting in the aortic ring assay than the wild-type form. Altogether, our results show that ADAMTS-12 displays antiangiogenic properties and protect the host toward tumor progression. [less ▲]

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See detailLa critique néokantienne de Kant et l'instauration d'une théorie descriptiviste de la perception
Dewalque, Arnaud ULg

in Dialogue : Canadian Philosophical Review = Dialogue : Revue Canadienne de Philosophie (2010), 49(3), 413-433

This paper contributes to explore the historical background of contemporary conceptualism. It suggests that a step forward toward a more promising understanding of this historical background can be made ... [more ▼]

This paper contributes to explore the historical background of contemporary conceptualism. It suggests that a step forward toward a more promising understanding of this historical background can be made if we focus, not on the much-discussed, controversial position of Kant, but rather on the straightforward position of some main representatives of classical neo-Kantianism. My main hypothesis is that criticisms of Kant’s transcendantal aesthetics coming from Paul Natorp (1854–1924) and Bruno Bauch (1877–1942) may be regarded as a significant historical source for the so-called “content” conceptualism (especially in McDowell’s version), insofar as they imply that the contents of perception are conceptual contents. [less ▲]

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See detailAuto-assemblage moléculaire électro-assisté d’organothiols mono- et bipodes sur cuivre
Maho, Anthony ULg

Master's dissertation (2010)

L’auto-assemblage moléculaire sur métaux actif (Cu, Zn, Ni, …) permet de conférer aux surfaces des propriétés protectrices spécifiques (protection contre la corrosion, …) et des fonctionnalités propres ... [more ▼]

L’auto-assemblage moléculaire sur métaux actif (Cu, Zn, Ni, …) permet de conférer aux surfaces des propriétés protectrices spécifiques (protection contre la corrosion, …) et des fonctionnalités propres dans des domaines d’applications spécifiques (lubrification, biocompatibilité, …). En particulier, la formation de monocouches auto-assemblées d’organothiols sur substrats de cuivre polycrystallin offre des défis particulièrement intéressants. Les films générés démontrent d’excellentes propriétés d’adhérence, d’organisation et de protection, d’autant plus renforcées si le cuivre fait l’objet d’une réduction électrochimique préalable. Jusqu’à présent, l’auto-assemblage moléculaire sur le cuivre est réalisé de manière « passive » par simple immersion du substrat après réduction électrochimique dans une solution d’organothiols. L’originalité apportée dans le cadre de ce mémoire consiste à réaliser un greffage « actif » par adsorption sous polarisation cathodique afin d’assister l’auto-assemblage des molécules d’organothiols sur le substrat de cuivre par application d’un potentiel approprié. L’objectif majeur de ce travail est donc de démontrer que l’adsorption sous polarisation permet de former des assemblages moléculaires d’organothiols avec des avantages non-négligeables en termes de gain de temps et de qualités élevées des monocouches. Outre des alkylthiols normaux possédant un monopied d’ancrage, des monocouches d’alkyldithiols et d’alkyldithiocarboxyliques, munies d’un bipied d’ancrage, seront caractérisées dans l’optique de former des films soit plus stables, soit plus facilement éliminables ou transitoires, respectivement. [less ▲]

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See detailA graphical analysis of Versailles garden promenades
Szanto, Catherine ULg

in Journal of Landscape Architecture (2010), 9(Spring), 54-59

Analyses of gardens are commonly encountered through plan and perspective views only – as if a garden in situ might be replaced by its representation in plan, and as if the actual experience of a garden ... [more ▼]

Analyses of gardens are commonly encountered through plan and perspective views only – as if a garden in situ might be replaced by its representation in plan, and as if the actual experience of a garden is limited to a succession of views. Yet, walking in the garden (any garden) is a much richer experience than simply encountering a succession of framed views. Being spatial environments, gardens are perceived and explored by looking, feeling, walking visitors. The graphical explorations in this essay are an attempt to explore the components and underlying structure of the spatial experiences inherent in any designed space. [less ▲]

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See detailMatériaux composites
Courard, Luc ULg

Learning material (2010)

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See detailAladdin nulling instrument
Barillot, Marc; Coudé Du Foresto, Vincent; Surdej, Jean ULg et al

in Spinoglio, L.; Epchtein, N. (Eds.) 3rd ARENA Conference: An Astronomical Observatory at CONCORDIA (Dome C, Antarctica) (2010)

The ALADDIN project aims at detecting warm dust populations around nearby main sequence stars. In order to achieve the significantly improved sensitivity with respect to existing instruments, the ... [more ▼]

The ALADDIN project aims at detecting warm dust populations around nearby main sequence stars. In order to achieve the significantly improved sensitivity with respect to existing instruments, the architecture of the system is focused and optimised for the mission: ALADDIN implements the nulling interferometry technique at the focal plane of a 2-telescope interferometer mounted on a rotating structural beam. Concerning the beam combining nulling instrument, the ALADDIN design is inherited from a Definition Study of the VLTI/GENIE instrument. In this paper, we demonstrate how the ALADDIN instrument preliminary definition can be made simpler and more representative of a space instrument than GENIE thanks to both the outstanding atmospheric properties of Dome C and the dedicated architecture of the system. Finally, we discuss the compatibility of the instrument with the Antarctic environment and constraints, and underline the experimental and industrial know-how learnt from the MAII and PERSEE nulling breadboards in which our Team is also involved. [less ▲]

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See detailFormation à la communication pour des directeurs d'école
Danse, Cédric ULg; Fossion, Gilles; Tuts, Jenny ULg et al

Learning material (2010)

Ce syllabus présente des aspects essentiels de la communication. Il s'intéresse en outre à la communication non violente en mettant l'accent sur l'assertivité et des techniques de gestion de conflits.

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