References of "2010"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailShould patients under long-term anti-TNF therapies be followed for tuberculosis contamination?
Reenaers, Catherine ULg; Belaiche, Jacques ULg; Louis, Edouard ULg

in Inflammatory Bowel Diseases (2010), 16(8), 1271-2

Detailed reference viewed: 35 (5 ULg)
Full Text
Peer Reviewed
See detailAnalysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk
Mahachie John, Jestinah ULg; Baurecht, H.; Rodriguez, E. et al

in Allergy (2010), 65(7), 875-882

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S ... [more ▼]

To cite this article: Mahachie John JM, Baurecht H, Rodriguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann H-E, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S. Analysis of the high-affinity IgE receptor genes reveals epistatic effects of FCER1A variants on total IgE levels and eczema risk. Allergy 2009; DOI: 10.1111/j.1398-9995.2009.02297.x. Abstract Background: High levels of total and allergen-specific IgE levels are a key feature in allergic diseases. The high-affinity receptor for IgE, which is composed of one alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits, represents the central receptor of IgE-induced reactions. In a genome-wide association scan, we recently identified associations between functional FCER1A variants and total serum IgE levels. Previous studies had reported linkage and association of FCER1B variants with IgE and atopic traits. The FCER1G gene has not yet been investigated with regard to atopy. Filaggrin (FLG) is the strongest known risk gene for eczema, in particular the allergic subtype of eczema. Methods: We investigated the association of FCER1A, FCER1B, and FCER1G variants with IgE in a large population-based cohort (n = 4261) and tested for epistatic effects using the model-based multifactor dimensionality reduction (MB-MDR) method. In addition, we investigated a potential interaction between FLG and FCER1A variants in a large collection of eczema cases (n = 1018) and population controls. Results: Three strongly correlated FCER1A polymorphisms were significantly associated with total and specific IgE levels as well as allergic sensitization. No associations were seen for FCER1B and FCER1G. After adjustment for FLG effects, a significant epistatic effect of the FCER1A variants rs10489854 and rs2511211 on eczema risk was detected. Conclusions: These results suggest that FCER1A variants by themselves and in combination influence IgE levels and act synergistically to influence eczema risk. [less ▲]

Detailed reference viewed: 61 (12 ULg)
Full Text
Peer Reviewed
See detailLe tabac et ses effets sur le système endocrinien
VALDES SOCIN, Hernan Gonzalo ULg; VROONEN, Laurent ULg; Latta, A. et al

in Revue Médicale de Liège (2010), 65(9), 498-501

Detailed reference viewed: 75 (6 ULg)
Full Text
Peer Reviewed
See detailDirect visualization of the vortex distributions in a superconducting film with a Penrose array of magnetic pinning centers: Symmetry induced giant vortex state
Kramer, R. B. G.; Silhanek, Alejandro ULg; Van de Vondel, J. et al

in Physica C: Superconductivity (2010), 470(19), 758-761

Using scanning Hall probe microscopy a direct visualization of the flux distribution in a Pb film covering a fivefold Penrose array of Co dots is obtained. We demonstrate that stable vortex configurations ... [more ▼]

Using scanning Hall probe microscopy a direct visualization of the flux distribution in a Pb film covering a fivefold Penrose array of Co dots is obtained. We demonstrate that stable vortex configurations can be found for fields H similar to 0.8H(1), H(1) and 1.6H(1), where H(1) corresponds to one flux quantum per pinning site. The vortex pattern at 0.8H(1) corresponds to one vacancy in one of the vertices of the thin tiles whereas at 1.6H(1) the vortex structure can be associated with one interstitial vortex inside each thick tile. Strikingly, for H = 1.6H(1) interstitial and pinned vortices arrange themselves in ring-like structures ("vortex corrals") which favor the formation of a giant vortex state at their center. (C) 2010 Published by Elsevier B.V. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailJean-Philippe Toussaint
Demoulin, Laurent ULg; Piret, Pierre

in Textyles : Revue des Lettres Belges de Langue Française (2010), 38

L'œuvre de Jean-Philippe Toussaint n'a à ce jour donné lieu à aucune publication monographique en français. Textyles a voulu remédier à cette lacune, en mettant en chantier un numéro pionnier et, à ce ... [more ▼]

L'œuvre de Jean-Philippe Toussaint n'a à ce jour donné lieu à aucune publication monographique en français. Textyles a voulu remédier à cette lacune, en mettant en chantier un numéro pionnier et, à ce titre, résolument ouvert : mettre en perspective les différentes facettes de l’œuvre en multipliant les angles d’approche, tel fut l’objectif qui présida à l’élaboration du présent dossier. Spécialistes des études littéraires, du cinéma et de la photographie s’y côtoient, qui développent des analyses s’attachant à dégager les modes de composition et les principales caractéristiques esthétiques de l’œuvre, à montrer comment elle radiographie les discours contemporains et à la situer dans l’histoire de la littérature. [less ▲]

Detailed reference viewed: 111 (11 ULg)
Full Text
Peer Reviewed
See detailLouvre-Lens : Le Louvre autrement : des coulisses aux expositions
Bodéré, Audrey; Drouguet, Noémie ULg

in CeROArt : Conservation, Exposition, Restauration d'Objets d'Art (2010), 5

Detailed reference viewed: 33 (5 ULg)
Full Text
Peer Reviewed
See detailPyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation.
Mortier, Jeremie; Frederick, Raphael; Ganeff, Corinne et al

in Biochemical Pharmacology (2010), 79(10), 1462-72

In this work, we aimed to build a 3D-model of NIK and to study the binding of pyrazolo[4,3-c]isoquinolines with a view to highlight the structural elements responsible for their inhibitory potency ... [more ▼]

In this work, we aimed to build a 3D-model of NIK and to study the binding of pyrazolo[4,3-c]isoquinolines with a view to highlight the structural elements responsible for their inhibitory potency. However, in the course of this work, we unexpectedly found that the pyrazolo[4,3-c]isoquinolines initially reported as NIK inhibitors were neither inhibitors of this enzyme nor of the alternative NF-kappaB pathway, but were in fact inhibitors of another kinase, the TGF-beta activated kinase 1 (TAK1) which is involved in the classical NF-kappaB pathway. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailManagement effects on net ecosystem carbon and GHG budgets at European crop sites
Ceschia, E.; Beziat, P.; Dejoux, J. F. et al

in Agriculture, Ecosystems & Environment (2010), 139

Detailed reference viewed: 53 (6 ULg)
See detailErzählte Kindsbräute bei Heinrich von Kleist, E.T.A. Hoffmann und Theodor Storm
Gerrekens, Louis ULg

in Detering, Heinrich; Fasold, Regina; Stein, Malte (Eds.) Zwischen Mignon und Lulu. Das Phantasma der Kindsbraut in Biedermeier und Realismus (2010)

Detailed reference viewed: 70 (3 ULg)
Full Text
See detailLeadership et genre : regard croisé de la gestion et de la psychanalyse
Cornet, Annie ULg; Cadalen, Sophie

in Gazette Cournot (La) (2010), 47

Detailed reference viewed: 81 (19 ULg)
Full Text
See detailEl doble juego de una vida y de una obra. Jorge Semprun y la literatura comprometida
Denis, Benoît ULg

in Pla, Xavier (Ed.) Jorge Semprun o les espirales de la memoria (2010)

Detailed reference viewed: 35 (0 ULg)
Full Text
Peer Reviewed
See detailLes corrélats cérébraux de le recollection et de la familiarité dans la maladie d’Alzheimer
Genon, Sarah ULg; Salmon, Eric ULg; Collette, Fabienne ULg et al

in Proceedings du XIeme colloque international sur le vieillissement cognitif (2010)

Detailed reference viewed: 27 (4 ULg)
Peer Reviewed
See detailFollicular fluids, immunological fingerprint and infertility
Lédée, N; Munaut, Carine ULg; PERRIER d'HAUTERIVE, Sophie ULg et al

Conference (2010)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailMaternal plasma soluble endoglin at 11-13 weeks's gestation in pre-eclampsia
Foidart, Jean-Michel ULg; Munaut, Carine ULg; Chantraine, Frédéric ULg et al

in Ultrasound in Obstetrics & Gynecology (2010), 35(6), 680-7

Objectives: To examine the performance of screening for preeclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein A (PAPP-A), placental growth ... [more ▼]

Objectives: To examine the performance of screening for preeclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein A (PAPP-A), placental growth factor (PlGF) and uterine artery lowest pulsatibility index (L-PI) at 11-13 weeks of gestation. Methods: Uterine artery L-PI, sEng, PAPP-A and PlGF were measured at 11-13 weeks in 90 singleton pregnancies that subsequently developed PE, including 30 that required delivery before 34 weeks (early-PE) and 60 with late-PE, and 180 unaffected controls. Screening performance for PE by maternal factors, sEng, PAPP-A, PlGF and uterine artery L-PI and their combinations was determined. Results: In early-PE, compared to controls, plasma sEng and uterine L-PI were significantly increased and serum PAPP-A and PlGF were decreased. In late-PE, compared to controls, serum PlGF was decreased and uterine L-PI was increased but plasma sEng and serum PAPP-A were not significantly different. In screening for early-PE, the detection rate at a 10% false positive rate was 46.7% for sEng alone and 96.3% for a combination of maternal factors, sEng, PlGF and uterine artery L-PI. Conclusions: Effective screening for early-PE can be provided by a combination of maternal factors, sEng, PlGF and uterine artery L-PI at 11-13 weeks. [less ▲]

Detailed reference viewed: 63 (11 ULg)
Full Text
See detailDeveloping Countries facing Global Warming: a Post-Kyoto Assessment. Round-table Debate
Ozer, Pierre ULg

in De Dapper, Morgan; Swinne, Danielle; Ozer, Pierre (Eds.) Developing Countries facing Global Warming: a Post-Kyoto Assessment. (2010)

This paper reports the results of a round-table debate organized by the Royal Academy for Overseas Sciences (RAOS) on Developing Countries facing Global Warming: a Post-Kyoto Assessment (Brussels, 13 June ... [more ▼]

This paper reports the results of a round-table debate organized by the Royal Academy for Overseas Sciences (RAOS) on Developing Countries facing Global Warming: a Post-Kyoto Assessment (Brussels, 13 June, 2009) to highlight the view of developing countries on adaptation to and mitigation of climate change. The participants convened to discuss the various aspects of climate change impacts and adaptation in developing countries preceding the Copenhagen Conference (UNFCCC COP 15) in December 2009. Here, we summarize the point of view of the two invited speakers representing developing countries. [less ▲]

Detailed reference viewed: 159 (20 ULg)
Full Text
Peer Reviewed
See detailDeletion of the late cornified envelope genes, LCE3C and LCE3B, is associated with rheumatoid arthritis.
Docampo Martinez, Elisa ULg; Rabionet, Raquel; Riveira-Munoz, Eva et al

in Arthritis and rheumatism (2010), 62(5), 1246-51

OBJECTIVE: The risk of rheumatoid arthritis (RA) is increased in the offspring of individuals affected with various autoimmune disorders, including psoriasis. Recently, the deletion of 2 genes from the ... [more ▼]

OBJECTIVE: The risk of rheumatoid arthritis (RA) is increased in the offspring of individuals affected with various autoimmune disorders, including psoriasis. Recently, the deletion of 2 genes from the late cornified envelope (LCE) gene cluster, LCE3C and LCE3B, has been associated with psoriasis in several populations. The purpose of this study was to assess whether this polymorphic gene deletion could also be involved in susceptibility to RA. METHODS: We tested for association between the LCE3C_LCE3B copy number variant and a single-nucleotide polymorphism in strong linkage disequilibrium with this variant (rs4112788) and RA in 2 independent case-control data sets (197 and 400 samples from patients with RA, respectively, and 411 and 567 samples from control subjects, respectively), collected at 4 Spanish hospitals. All samples were directly typed for presence of the LCE3C_LCE3B deletion (LCE3C_LCE3B-del) by polymerase chain reaction, and association analysis was performed using the SNPassoc R package. RESULTS: An association of homozygosity for the LCE3C_LCE3B-del and rs4112788 C allele with the risk of RA was observed in the first data set and was replicated in an independent case-control set. A combined analysis showed an overall P value of 0.0012 (odds ratio [OR] 1.45, 95% confidence interval [95% CI] 1.16-1.81) for association of the LCE3C_LCE3B-del. When the analysis was stratified for serologic data, we observed association in anti-cyclic citrullinated peptide (anti-CCP)-positive patients (P = 0.012, OR 1.51 [95% CI 1.09-2.13]) but not in anti-CCP-negative patients. CONCLUSION: We have identified an association between the LCE3C_LCE3B-del and RA, and we have verified a pleiotropic effect of a common genetic risk factor (LCE3C_LCE3B-del) for autoimmune diseases that is involved in both psoriasis and RA. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailMicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard
Heusschen, Roy ULg; van Gink, Matthijs; Griffioen, Arjan et al

in Biochimica et Biophysica Acta - Reviews on Cancer (2010), 1805

Detailed reference viewed: 6 (1 ULg)
Full Text
Peer Reviewed
See detailManagement effects on European cropland respiration
Eugster, W.; Moffat, A. M.; Ceschia, E. et al

in Agriculture, Ecosystems & Environment (2010), 139

Detailed reference viewed: 64 (7 ULg)