References of "2010"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailUse of ISSR markers to assess genetic diversity of African edible seeded Citrullus lanatus landraces
Dje, Yao; Tahi, C. G.; Zoro Bi, A. I. et al

in Scientia Horticulturae (2010), 124

Detailed reference viewed: 42 (5 ULg)
Full Text
Peer Reviewed
See detailComparison of accuracy of sonography, rectal palpation, and pregnancy-associated glycoproteins tests for pregnancy diagnosis in cows
Gajewski, Z.; Petrajtis, M.; Melo de Sousa, Noelita ULg et al

in Proceedings of the XIth Middle European Buiatrics Congress (2010)

Detailed reference viewed: 40 (2 ULg)
Full Text
Peer Reviewed
See detailProgressive juvenile glomerulonephropathy in 16 related French Mastiff (Bordeaux) Dogs
Lavoué, Rachel ULg; van der Lugt, J.J.; Day, M.J. et al

in Journal of Veterinary Internal Medicine (2010), 24(2), 314-322

Detailed reference viewed: 36 (7 ULg)
Full Text
Peer Reviewed
See detailFurther pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.
Van de Veire, Sara; Stalmans, Ingeborg; Heindryckx, Femke et al

in Cell (2010), 141(1), 178-90

Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been challenged by Bais et al. Here we take advantage of carcinogen-induced and transgenic tumor models as ... [more ▼]

Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been challenged by Bais et al. Here we take advantage of carcinogen-induced and transgenic tumor models as well as ocular neovascularization to report further evidence in support of our original findings of PlGF as a promising target for anticancer therapies. We present evidence for the efficacy of additional anti-PlGF antibodies and their ability to phenocopy genetic deficiency or silencing of PlGF in cancer and ocular disease but also show that not all anti-PlGF antibodies are effective. We also provide additional evidence for the specificity of our anti-PlGF antibody and experiments to suggest that anti-PlGF treatment will not be effective for all tumors and why. Further, we show that PlGF blockage inhibits vessel abnormalization rather than density in certain tumors while enhancing VEGF-targeted inhibition in ocular disease. Our findings warrant further testing of anti-PlGF therapies. [less ▲]

Detailed reference viewed: 128 (11 ULg)
Full Text
Peer Reviewed
See detailEffects of HPV-16 E5, E6 and E7 Proteins on Survival, Adhesion, Migration and Invasion of Trophoblastic Cells
Boulenouar, S.; Weyn, C.; Van Noppen, M. et al

in Carcinogenesis (2010), 31(3), 473-80

Amongst high-risk human papillomaviruses (HPV), HPV-16 infection is the most prevalent causative factor for cervical cancer. Beside other mucosal targets, HPV-16 was reported to infect the placenta and to ... [more ▼]

Amongst high-risk human papillomaviruses (HPV), HPV-16 infection is the most prevalent causative factor for cervical cancer. Beside other mucosal targets, HPV-16 was reported to infect the placenta and to replicate in trophoblastic cells. Since these cells share invasive properties of tumoral cells, they represent an ideal model to investigate several oncogenic processes. In the present work, we analyzed the impacts of HPV-16 E5, E6 and E7 oncoproteins on the trophoblastic model. Our results showed that E5 impaired the viability of trophoblastic and cervical cell lines but E6 and E7, favouring cell growth, neutralised the E5 cytotoxic effect. In addition, E5 decreased the adhesiveness of trophoblastic cells to the tissue culture plastic and to endometrial cells similarly as previously described for E6 and E7. E5 and E6 plus E7 increased also their migration and their invasive properties. Cells expressing HPV-16 early proteins under the control of the LCR endogenous promoter displayed growth advantage and were also more motile and invasive compared to control cells. Interestingly, the E-cadherin was down regulated in trophoblastic cells expressing E5, E6 and E7. NF-kB and AP-1 activities were also enhanced. In conclusion, HPV-16 early proteins enhanced trophoblastic growth and intensify the malignant phenotype by impairing cell adhesion leading to increased cellular motile and invasive properties. HPV-16 E5 participated, with E6 and E7, in these changes by impairing Ecadherin expression, a hallmark of malignant progression. [less ▲]

Detailed reference viewed: 70 (6 ULg)
Full Text
Peer Reviewed
See detailPresence of IL-5 and Ige-antibodies to staphylococcal enterotoxins in nasal polyps is associated with co-morbid asthma
Bachert, Claus; Zhang, Nan; Holtappels, Gabriele et al

in Journal of Allergy and Clinical Immunology (The) (2010), 126(5), 962-968

Detailed reference viewed: 21 (7 ULg)
See detailLe Cannabis: historique, culture et modes d'utilisation
Theunis, Laetitia ULg; De Backer, Benjamin ULg; Charlier, Corinne ULg

in Regards croisés sur le Cannabis (2010)

Detailed reference viewed: 57 (20 ULg)
Full Text
Peer Reviewed
See detailThe permease gene nagE2 is the key to N-acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi-level control
Nothaft, Harald; Rigali, Sébastien ULg; Boomsma, B. et al

in Molecular Microbiology (2010), 75((5)), 1133-44

Detailed reference viewed: 17 (2 ULg)
Full Text
Peer Reviewed
See detailNew Biological Investigations on 3-Bromophenyl 6-Acetoxymethyl-2-oxo-2H-1-Benzopyran-3-Carboxylate as Anti-angiogenic Agent
Hemmer, M.; Kempen, Isabelle; De Tullio, Pascal ULg et al

in Drug Development Research (2010), 71

The development of blood vessels inside tumors is required to provide the nutrients and oxygen needed for tumor growth and to allow the spread of cancer cells at a distance to form metastasis ... [more ▼]

The development of blood vessels inside tumors is required to provide the nutrients and oxygen needed for tumor growth and to allow the spread of cancer cells at a distance to form metastasis. Angiogenesis is also implicated in ocular diseases like age-related macular degeneration. The present work describes the potential anti-angiogenic properties of a coumarinic derivative, 3-bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate (IK9), previously described as a potent inhibitor of HT 1080 fibrosarcoma cell invasion in vitro and tumor growth in vivo. In vivo, ex vivo, and in vitro models were used to delineate the anti-angiogenic properties of IK9. The anti-angiogenic effect of IK9 was demonstrated in vivo in a choroidal neovascularization mice model and additionally ex vivo in a rat aortic ring assay where it was more active than the known matrix metalloproteinase inhibitor Ro 28-2653. IK9 did not affect apoptosis, proliferation, or endothelial cell invasiveness in vitro. These findings suggest a complex mechanism of action of the compound via direct or indirect effects on endothelial cell properties. This study identifies IK9 as a new potent inhibitor of angiogenesis and suggests its potential use as a therapeutic agent. [less ▲]

Detailed reference viewed: 81 (14 ULg)
Full Text
Peer Reviewed
See detailChoix technologiques pour l’informatisation de l’Atlas Linguistique de la Wallonie
Mazziotta, Nicolas ULg

in Upton, Clive; Heselwood, Barry (Eds.) Proceedings of Methods XIII. Papers from the Thirteenth International Conference on Methods in Dialectology, 2008 (2010)

Detailed reference viewed: 27 (6 ULg)
Full Text
See detailEvaluation of the effect of load eccentricity in a tensile pull-off test on bond strength
Courard, Luc ULg; Garbacz, Andrezj

Report (2010)

The report presents the results of a research project and the impact of incorrect design on tensile strength values. According to results of laboratory experiments and modelling, it can be observed that ... [more ▼]

The report presents the results of a research project and the impact of incorrect design on tensile strength values. According to results of laboratory experiments and modelling, it can be observed that, if there is an influence of 2° and 4° angle of inclination on pull-off bond strength, it is however not statistically significant: the decrease of pull-off strength is usually no larger than 14% for 4°. [less ▲]

Detailed reference viewed: 59 (0 ULg)
Full Text
Peer Reviewed
See detailOut of Africa: north-westwards Pleistocene expansions of the heather Erica arborea
Desamore, Aurélie ULg

Poster (2010)

ntroduction Erica arborea L. is a dominant element of the circum-Mediterranean region. Its broad, disjunct distribution, ranging from Macaronesia to eastern Africa, is consistent with the fragmentation of ... [more ▼]

ntroduction Erica arborea L. is a dominant element of the circum-Mediterranean region. Its broad, disjunct distribution, ranging from Macaronesia to eastern Africa, is consistent with the fragmentation of the evergreen tropical forests that dominated Europe and North Africa in the Tertiary. (fig.1) Aim Is the current disjunct distribution of E. arborea a relict of a once wider distribution or a recent range expansion in response to the establishment of suitable conditions ? [less ▲]

Detailed reference viewed: 15 (1 ULg)
Peer Reviewed
See detailStudy of the degradation mechanisms of Prussian Blue in paint layers by X-ray absorption spectroscopy
Samain, Louise ULg; Silversmit, Geert; Vekemans, Bart et al

Conference (2010)

Detailed reference viewed: 63 (8 ULg)
Full Text
Peer Reviewed
See detailSecuring Transient Stability using Time-Domain Simulations within an Optimal Power Flow
Zarate-Minano, Rafael; Van Cutsem, Thierry ULg; Milano, Federico et al

in IEEE Transactions on Power Systems (2010), 25(1), 243-253

This paper provides a methodology to restore transient stability. It relies on a well-behaved optimal power flow model with embedded transient stability constraints. The proposed methodology can be used ... [more ▼]

This paper provides a methodology to restore transient stability. It relies on a well-behaved optimal power flow model with embedded transient stability constraints. The proposed methodology can be used for both dispatching and redispatching. In addition to power flow constraints and limits, the resulting optimal power flow model includes discrete time equations describing the time evolution of all machines in the system. Transient stability constraints are formulated by reducing the initial multi-machine model to a one-machine infinite-bus equivalent. This equivalent allows imposing angle bounds that ensure transient stability. The proposed optimal power flow model is tested and analyzed using an illustrative 9-bus system, the well-known New England 39-bus, 10-machine system and a real-world 1228-bus system with 292 synchronous machines. [less ▲]

Detailed reference viewed: 139 (17 ULg)
Full Text
See detailL’édition pour la jeunesse en Belgique francophone : de la nécessité faite vertu à la mondialisation
Habrand, Tanguy ULg

in Pinhas, Luc; Foucault, Jean; Manson, Michel (Eds.) L'édition de jeunesse francophone face à la mondialisation (2010)

Detailed reference viewed: 28 (4 ULg)
Full Text
Peer Reviewed
See detailLe droit européen de la concurrence au banc des accusés
Petit, Nicolas ULg

in Revue de la Faculté de Droit de l'Université de Liège (2010), (2),

Detailed reference viewed: 51 (7 ULg)
Full Text
Peer Reviewed
See detailIncidence of sport injuries in elite young athletes of the Grand-duchy of Luxembourg
Frisch, Anne ULg; Urhausen, A.; Seil et al

in Buys, R.; Buerkers, M.; Daly, D. (Eds.) Programma boek final of the 12th International ACAPS Conference (2010)

Detailed reference viewed: 47 (4 ULg)