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See detailIntestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease and the impact of infliximab therapy.
Arijs, Ingrid; Quintens, Roel; Lemaire, Katleen et al

in Journal of Crohn’s and Colitis [=JCC] (2010)

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See detailUn "Glossario dei glossari" degli antichi volgari italiani: preliminari, risultati, prospettive
Aresti, Alessandro ULg

in Bollettino dell'Atlante Lessicale degli Antichi Volgari Italiani (2010), 3

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See detailA maġribī copy of the Kitāb al-Faraj baʿd aš-Šidda, by the ʿIrāqī qāḍī at-Tanūḫī. Study of a Manuscript of Liège University (Belgium)
Franssen, Elise ULg

in Journal of Islamic Manuscripts (2010), 1

Author introduces the Arabic manuscript collection in Liège, Belgium, which is not as widely known as it deserves to be. She singles out one particular manuscript, an 11/16th century copy of the well ... [more ▼]

Author introduces the Arabic manuscript collection in Liège, Belgium, which is not as widely known as it deserves to be. She singles out one particular manuscript, an 11/16th century copy of the well-known work Kitāb al-Faraj baʿd aš-Šidda, by the ʿIrāqī qāḍī at-Tanūhkhī (327-384/939-994). She describes the manuscript and places her detailed description within the framework of the modern scholarly and bibliographical references on Abbasid literature in general and on recent developments in codicology and paleography in particular. She also discusses the relationship of the Liège manuscript with some of the printed editions of the Kitāb al-Faraj baʿd aš-Šidda. [less ▲]

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See detailDroits de l'homme et "choc des civilisations"
Delruelle, Edouard ULg

in Revue Trimestrielle des Droits de l'Homme (2010)

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See detailIMA Commission on New Minerals, Nomenclature and Classification (CNMNC), Newsletter 3
Williams, Pete; Hatert, Frédéric ULg; Pasero, Marco et al

in Mineralogical Magazine (2010), 74

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See detailL'architecture, producteur de "lien social' ou acteur dans les "luttes sociales"?
Brausch, Géraldine ULg

in Dassonville, Chantal; Cohen, Maurizio (Eds.) Architecture, Wallonie-Bruxelles. Inventaire #0 Inventories 2005-2010 (2010)

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See detailCotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning.
Baron, Frédéric ULg; Lechanteur, Chantal ULg; Willems, Evelyne ULg et al

in Biology of Blood & Marrow Transplantation (2010), 16(6), 838-47

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD ... [more ▼]

Recent studies have suggested that coinfusion of mesenchymal stem cells (MSCs) the day of hematopoietic cell transplantation (HCT) might promote engraftment and prevent graft-versus-host disease (GVHD) after myeloablative allogeneic HCT. This prompted us to investigate in a pilot study whether MSC infusion before HCT could allow nonmyeloablative (NMA) HCT (a transplant strategy based nearly exclusively on graft-versus-tumor effects for tumor eradication) from HLA-mismatched donors to be performed safely. Twenty patients with hematologic malignancies were given MSCs from third party unrelated donors 30-120 minutes before peripheral blood stem cells (PBSCs) from HLA-mismatched unrelated donors, after conditioning with 2 Gy total body irradiation (TBI) and fludarabine. The primary endpoint was safety, defined as a 100-day incidence of nonrelapse mortality (NRM) <35%. One patient had primary graft rejection, whereas the remaining 19 patients had sustained engraftment. The 100-day cumulative incidence of grade II-IV acute GVHD (aGVHD) was 35%, whereas 65% of the patients experienced moderate/severe chronic GVHD (cGVHD). One-year NRM (10%), relapse (30%), overall survival (OS) (80%) and progression-free survival (PFS) (60%), and 1-year incidence of death from GVHD or infection with GVHD (10%) were encouraging. These figures compare favorably with those observed in a historic group of 16 patients given HLA-mismatched PBSCs (but no MSCs) after NMA conditioning, which had a 1-year incidence of NRM of 37% (P = .02), a 1-year incidence of relapse of 25% (NS), a 1-year OS and PFS of 44% (P = .02), and 38% (P = .1), respectively, and a 1-year rate of death from GVHD or infection with GVHD of 31% (P = .04). In conclusion, our data suggest that HLA-mismatched NMA HCT with MSC coinfusion appeared to be safe. [less ▲]

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See detailQui dispose des dispositifs de médiation ?
Servais, Christine ULg

in Questions de Communication (2010), 10

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See detailLa nouvelle économie sociale et solidaire : une repolitisation du quotidien ?
Frère, Bruno ULg

Article for general public (2010)

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See detailMagneto-thermal phenomena in bulk high temperature superconductors subjected to applied AC magnetic fields
Vanderbemden, Philippe ULg; Laurent, Philippe ULg; Fagnard, Jean-François ULg et al

in Superconductor Science and Technology (2010), 23

In the present work we study, both theoretically and experimentally, the temperature increase in a bulk high temperature superconductor subjected to applied AC magnetic fields of large amplitude. We ... [more ▼]

In the present work we study, both theoretically and experimentally, the temperature increase in a bulk high temperature superconductor subjected to applied AC magnetic fields of large amplitude. We calculate analytically the equilibrium temperatures of the bulk sample as a function of the experimental parameters using a simple critical state model for an infinitely long type-II superconducting slab or cylinder. The results show the existence of a limit heat transfer coefficient (AUlim) separating two thermal regimes with different characteristics. The theoretical analysis predicts a ‘forbidden’ temperature window within which the temperature of the superconductor can never stabilize when the heat transfer coefficient is small. In addition, we determine analytical expressions for two threshold fields Htr1 and Htr2 characterizing the importance of magneto-thermal effects and show that a thermal runaway always occurs when the field amplitude is larger than Htr2. The theoretical predictions of the temperature evolution of the bulk sample during a self-heating process agree well with the experimental data. The simple analytical study presented in this paper enables order of magnitude thermal effects to be estimated for simple superconductor geometries under applied AC magnetic fields and can be used to predict the influence of experimental parameters on the self-heating characteristics of bulk type-II superconductors. [less ▲]

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See detailSurgical Pleth Index to assess the anti-nociceptive component of general anaesthesia: Comparison with haemodynamic parameters and identification of confounding factors: 3AP3--3
HANS, Grégory ULg; Bonhomme, V.; Maquoi, I. et al

in European Journal of Anaesthesiology (2010), 27(47), 50

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See detailEffect of intravenous infusion of lidocaine on spontaneous recovery from cisatracurium-induced neuromuscular block: Preliminary results: 9AP4--3
HANS, Grégory ULg; Defresne, A.; Ki, B. et al

in European Journal of Anaesthesiology (2010), 27(47), 149

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See detailNovel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup.
Rodriguez, Maria Margarita; Power, Pablo; Sader, Helio et al

in Antimicrobial agents and chemotherapy (2010), 54(7), 3070-1

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See detailNovel peptide inhibiting both TEM-1 beta-lactamase and penicillin-binding proteins.
Phichith, Denis; Bun, Sylvie; Padiolleau-Lefevre, Severine et al

in The FEBS journal (2010), 277(23), 4965-72

9G4H9, a catalytic antibody displaying beta-lactamase-like activity, has been developed by the anti-idiotypic approach using beta-lactamase as the first antigen. Thus 9G4H9 represents the 'internal image ... [more ▼]

9G4H9, a catalytic antibody displaying beta-lactamase-like activity, has been developed by the anti-idiotypic approach using beta-lactamase as the first antigen. Thus 9G4H9 represents the 'internal image' of beta-lactamase. We selected a cyclic peptide anchored to a bacteriophage M13 library using 9G4H9 as the target. Pep90 is a cyclic heptapeptide enclosed between two cysteine residues. We showed that Pep90 could inhibit both TEM-1 beta-lactamase (K(i) = 333 mum) and several penicillin-binding proteins (IC(5)(0) values ranging from 6-62 mum). We determined that the tryptophan residue of Pep90 is of crucial importance for its inhibitory activity. Using Pep90 as a scaffold, we generated a new class of peptidomimetics that retained inhibitory activity towards TEM-1 beta-lactamase. [less ▲]

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See detailThe 900-yr sedimentary record of Lago Thompson, Northern Chilean Patagonia
Fagel, Nathalie ULg; Nuttin, L.; Bertrand, S. et al

Poster (2010)

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See detailPierre Alechinsky. Récit d’un itinéraire pictural
Bawin, Julie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2010)

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See detailA survey of honey bee colony losses in Belgium, fall 2008 to spring 2009
Nguyen, Bach Kim ULg; Mignon, Jacques ULg; Laget, D. et al

Conference (2010)

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See detailThe umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood.
Zeddou, Mustapha ULg; Briquet, Alexandra ULg; Relic, Biserka ULg et al

in Cell Biology International (2010), 34(7), 693-701

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these ... [more ▼]

Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these cells can be isolated are still under discussion. Whereas BM (bone marrow) is presented as the main source of MSC, despite the invasive procedure related to this source, the possibility of isolating sufficient numbers of these cells from UCB (umbilical cord blood) remains controversial. Here, we present the results of experiments aimed at isolating MSC from UCB, BM and UCM (umbilical cord matrix) using different methods of isolation and various culture media that summarize the main procedures and criteria reported in the literature. Whereas isolation of MSC were successful from BM (10:10) and (UCM) (8:8), only one cord blood sample (1:15) gave rise to MSC using various culture media [DMEM (Dulbecco's modified Eagle's medium) +5% platelet lysate, DMEM+10% FBS (fetal bovine serum), DMEM+10% human UCB serum, MSCGM] and different isolation methods [plastic adherence of total MNC (mononuclear cells), CD3+/CD19+/CD14+/CD38+-depleted MNC and CD133+- or LNGFR+-enriched MNC]. MSC from UCM and BM were able to differentiate into adipocytes, osteocytes and hepatocytes. The expansion potential was highest for MSC from UCM. The two cell populations had CD90+/CD73+/CD105+ phenotype with the additional expression of SSEA4 and LNGFR for BM MSC. These results clearly exclude UCB from the list of MSC sources for clinical use and propose instead UCM as a rich, non-invasive and abundant source of MSC. [less ▲]

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