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See detailCentral neuromodulation in cluster headache patients treated with occipital nerve stimulators: A PET study
Magis, Delphine ULg; Bruno, Marie-Aurélie ULg; Fumal, Arnaud ULg et al

in Acta Neurologica Belgica (2010), 110(Suppl 1), 17

OBJECTIVES: Use functional brain imaging to explore activity changes in centres involved in trigeminal pain processing and control before and after occipital neurostimulation in drug-resistant chronic ... [more ▼]

OBJECTIVES: Use functional brain imaging to explore activity changes in centres involved in trigeminal pain processing and control before and after occipital neurostimulation in drug-resistant chronic cluster headache patients. BACKGROUND: Occipital nerve stimulation (ONS) provides relief to about 60% of patients suffering from drug-resistant chronic cluster headache (drCCH). Its mode of action, however, remains elusive, but the long latency to meaningful effect suggests that ONS induces slow neuromodulation. METHODS: Ten drCCH patients underwent an 18FDG-PET scan after ONS durations varying between 0 and 30 months. All were scanned with ongoing ONS (ON) and with the stimulator switched OFF. RESULTS: After 6-30 months of ONS, 3 patients were pain free and 4 had a ≥ 90% reduction of attack frequency (responders). In patients overall compared to controls, several areas of the pain matrix were hypermetabolic: ipsilateral hypothalamus, midbrain and ipsilateral lower pons. All normalized after ONS, except the hypothalamus. Switching ON or OFF the stimulator had little influence on brain glucose metabolism. The perigenual anterior cingulate cortex (PACC) was hyperactive in ONS responders compared to non-responders. INTERPRETATION AND CONCLUSIONS: Metabolic normalization in the pain neuromatrix and lack of short-term changes induced by the stimulation support the hypothesis that ONS acts in drCCH through slow neuromodulatory processes. Selective activation in responders of PACC, a pivotal structure in the endogenous opioid system, suggests that ONS may restore balance within dysfunctioning pain control centres. That ONS is nothing but a symptomatic treatment might be illustrated by the persistent hypothalamic hypermetabolism which could explain why autonomic attacks may persist despite pain relief and why cluster attacks recur shortly after stimulator arrest. [less ▲]

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See detailÀ quelles conditions la formation initiale peut-elle contribuer au développement professionnel des enseignants et formateurs d’enseignants
Beckers, Jacqueline ULg

in Paquay, L.; Wouters, P.; Van Nieuwenhoven, C. (Eds.) Évaluation et développement professionnel (2010)

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See detailTesting for one-sided alternatives in nonparametric censored curve comparison
Heuchenne, Cédric ULg; Pardo Fernandez, Juan-Carlos

in Proceedings of the 28th European Meeting of Statisticians. (2010)

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See detailInterfacial area measurement in a catalytic distillation packing using high energy x-ray CT
Aferka, Saïd ULg; Marchot, Pierre ULg; Crine, Michel ULg et al

in Chemical Engineering Science (2010), 65(1), 511-516

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on ... [more ▼]

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on processing of tomographic images. It is validated by comparing specific surface area determined on dry packings (Mellapak™ 752Y and Katapak™ SP12) tomographic binary images (gas and solid) to values announced by manufacturers, based on geometrical considerations. These data agree fairly well. However, tomographic images show that the specific area is not distributed uniformly over the height of a packing element due to the presence of perforations in corrugated sheets and of wall wipers between the packing and the column wall. X-ray tomography is a unique technique to access to the spatial distribution of these geometrical details in a non-intrusive way. The method used to determine the specific surface area of dry packing is then applied to irrigated packing in order to determine the gas–liquid interfacial area. The axial distribution of the interfacial area is non-uniform and is correlated to the packing specific area. The maxima of the specific surface area correspond to the presence of wall wipers. The gas–liquid interfacial area averaged over the column length is determined. It increases logically with the liquid superficial velocity and slightly with the gas velocity. The effect of the gas velocity is however more pronounced when reaching loading point. [less ▲]

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See detailStochastic analysis of a stadium roof from deterministic wind tunnel measurements
Blaise, Nicolas ULg; Denoël, Vincent ULg

in 13th International Conference on Wind Engineering (2010)

Dynamic analyses of structures under buffeting wind loads can be performed in a deterministic (Clough and Penzien, 1997) or stochastic (Preumont, 1994) context, both with a modal approach for ... [more ▼]

Dynamic analyses of structures under buffeting wind loads can be performed in a deterministic (Clough and Penzien, 1997) or stochastic (Preumont, 1994) context, both with a modal approach for computational efficiency reasons. In the first option, the forces are deterministically given, and the uncoupled modal equations of motion are solved either in the time domain with a stepby- step method, either in the frequency domain, with Fourier transformation. In the second option, the analysis relies on the determination of the Power Spectral Density (PSD) matrix of the structural response given that of the loading. The choice of one or another method usually depends on whether the loading is provided in the time or frequency domain and as a deterministic (a single time history) or stochastic manner. From a designer’s point of view, the wind loading can be defined using design codes (e.g. Eurocode, 2005) where analytical expressions of (i) the PSD of wind velocities (Davenport, Von Karman, etc) (ii) the coherence functions and (iii) the pressure coefficients are given to compute, finally, (iv) the PSD of the aerodynamic pressures. Design engineers are usually familiar with this probabilistic approach. Alternatively, the design may be conducted from aerodynamic pressures measured in a wind tunnel. This approach is more realistic than the aforementioned codified procedure since a number of phenomena as (a) the aerodynamic instabilities, (b) aerodynamic admittance (Scanlan and Jones, 1999), (c) site effects are taken into account. Pressures are thus given as unique (deterministic) time histories at each sensor. In a Finite Element context and a modal analysis, the generalized forces are computed from the measured pressures. With the firm wish to perform the analysis in a stochastic manner (for a number of good reasons mentioned next), we suggest to fit a probabilistic model to the measured data. Such a model could be fitted to the measured pressures right away, or any other subsequent quantity such as the generalized forces. The following discussion is about the most favorable quantity that has to be fitted and how to do it appropriately in view of typical measurement imperfections. [less ▲]

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See detailRésolution de problèmes et représentations : construction de dessins libres ou utilisation de schémas prédéfinis ?
Fagnant, Annick ULg; Vlassis, Joëlle

in Congrès international. Actualité de al recherche en éducation et en formation. AREF 2010 (2010)

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See detailEn las montañas de la locura
Lovecraft, Howard Phillips; Willson, Patricia ULg

Book published by Libros del Zorro Rojo (2010)

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See detailA cell based modelling framework for skeletal tissue engineering applications
Geris, Liesbet ULg; Van Liedekerke, Paul; Smeets, Bart et al

in Journal of Biomechanics (2010), 43(5), 887-892

In this study, a cell based lattice free modelling framework is proposed to study cell aggregate behaviour in bone tissue engineering applications. The model encompasses cell-to-cell and cell environment ... [more ▼]

In this study, a cell based lattice free modelling framework is proposed to study cell aggregate behaviour in bone tissue engineering applications. The model encompasses cell-to-cell and cell environment interactions such as adhesion, repulsion and drag forces. Oxygen, nutrients, waste products, growth factors and inhibitors are explicitly represented in the model influencing cellular behaviour. Furthermore, a model for cell metabolism is incorporated representing the basic enzymic reactions of glycolysis and the Krebs cycle. Various types of cell death such as necrosis, apoptosis and anoikis are implemented. Finally, an explicit model of the cell cycle controls the proliferation process, taking into account the presence or absence of various metabolites, sufficient space and mechanical stress. Several examples are presented demonstrating the potential of the modelling framework. The behaviour of a synchronised cell aggregate under ideal circumstances is simulated, clearly showing the different stages of the cell cycle and the resulting growth of the aggregate. Also the difference in aggregate development under ideal (normoxic) and hypoxic conditions is simulated, showing hypoxia induced necrosis mainly in the centre of the aggregate grown under hypoxic conditions. The next step in this research will be the application of this modelling framework to specific experimental set-ups for bone tissue engineering applications. (C) 2009 Elsevier Ltd. All rights reserved. [less ▲]

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See detailASCID : le noyau centrral de douze facteurs expliquant la conduite en éducation thérapeutique du patient
Leclercq, Dieudonné ULg

in Education Thérapeutique du Patient [=ETP] = Therapeutic Patient Education [=TPE] (2010), 2(2), 213-221

Abstract – ASCID: the core of 12 factors that explain behavior in patient education. Introduction: Professionals involved in Patient Education need to have a good understanding of the (numerous) factors ... [more ▼]

Abstract – ASCID: the core of 12 factors that explain behavior in patient education. Introduction: Professionals involved in Patient Education need to have a good understanding of the (numerous) factors that affect, in a person, her becoming aware, then her decision, then her putting it into practice in a lasting and efficient way. For this purpose, we propose a model we have developed during several years in CERES (University of Liège) as well as in DPSS (University of Paris 13), named “Factors of production and perseveration in actions”. If these factors are designated by the first letters of their names, at the heard of the model stands the acronym ASCID (Attitudes, Skills, Cognition, Identity, Decision). Objectives: This model, conceived for health and environment education is not limited to therapeutic patient education, but it fits it very well. The interest and the fecundity of this model have been put to test during more than 25 years with cohorts of students and professionals involved in TPE to analyze situations, cases, and to conceive relevant course of action for the educator and the patient. Description: Methods of diagnostic and of action in TPE superimposed themselves to the model of patient functioning. To help readers assimilate this complex model, we start with a familiar case (AIDS) and we will use frequently cases to illustrate theoretical concepts. [less ▲]

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See detailPeroxisomal β-oxidation and Production of γ-decalactone by the Yeast Rhodotorula aurantiaca
Alchihab, Mohamed ULg; Dubois Dauphin, Robin ULg; Aguedo, Mario ULg et al

in Notulae Botanicae Horti Agrobotanici Cluj-Napoca (2010), 2

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See detailUVIS observations of the FUV OI and CO 4P Venus dayglow during the Cassini flyby
Hubert, Benoît ULg; Gérard, Jean-Claude ULg; Gustin, Jacques ULg et al

in Icarus (2010), 207

We analyze FUV spatially-resolved dayglow spectra obtained at 0.37 nm resolution by the UVIS instrument during the Cassini flyby of Venus. We use a least-squares fit method to determine the brightness of ... [more ▼]

We analyze FUV spatially-resolved dayglow spectra obtained at 0.37 nm resolution by the UVIS instrument during the Cassini flyby of Venus. We use a least-squares fit method to determine the brightness of the OI emissions at 130.4 and OI 135.6 nm, and of the bands of the CO fourth positive system which are dominated by fluorescence scattering. We compare the brightness observed along the UVIS foot track of the two OI multiplets with that deduced from a model of the excitation of these emissions by photoelectron impact on O atoms and resonance scattering of the solar 130.4 nm emission. The large optical thickness 130.4 nm emission is accounted for using a radiative transfer model. The airglow intensities are calculated along the foot track and found to agree with the observed 130.4 nm brightness within ˜10%. The modeled OI 135.6 nm brightness is also well reproduced by the model. The oxygen density profile of the VTS3 model is found to be consistent with the observations. We find that self-absorption of the (0, v″) bands of the fourth positive emission of CO is important and we derive a CO vertical column of about 6.4 × 10[SUP]15[/SUP] cm[SUP]‑2[/SUP] in close agreement with the value provided by the VTS3 empirical atmospheric model. [less ▲]

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See detailThéorie et pratique de la négociation dans le cadre des marchés publics
Durviaux, Ann-Lawrence ULg

Conference given outside the academic context (2010)

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See detailChimie (2e partie)
Heinrichs, Benoît ULg

Learning material (2010)

Detailed reference viewed: 65 (18 ULg)