References of "2009"
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See detailRespiratory inflammation in endurance horses
Van Erck, Emmanuelle ULg; Art, Tatiana ULg

in Tessier, Caroline; Gerber, Vincent (Eds.) Abstract book: 4th World Equine Airways Symposium (WEAS) (2009)

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See detailEmerging therapies for ionizing radiation-associated skin field carcinogenesis.
Pierard, Gérald ULg; Pierard, Claudine ULg; Paquet, Philippe ULg et al

in Expert Opinion on Pharmacotherapy (2009), 10(5), 813-21

BACKGROUND: Radiodermatitis in its acute and chronic presentations represents a set of specific adverse effects resulting from ionizing radiations. Skin-field cancerization is another condition associated ... [more ▼]

BACKGROUND: Radiodermatitis in its acute and chronic presentations represents a set of specific adverse effects resulting from ionizing radiations. Skin-field cancerization is another condition associated to or independent of clinically recognizable radiodermatitis. This condition leads to the risk of later occurrence of skin malignancies. METHOD: Review of the current and most pertinent peer-reviewed publications with the addition of personal perspectives. RESULT/CONCLUSION: The presence of field cancerization encompasses subclinical changes, precursors of malignant alterations, as well as single or multiple primary neoplasms and local neoplastic recurrences. These tumours commonly require repeated treatments over time and cause significant morbidity. In general, specific tumour-directed treatments using ablative or destructive techniques require regular follow-up and screening for disclosing any further neoplasm. Another strategy corresponding to field-directed treatment targets a larger area of irradiated skin to reduce the risk of developing second neoplasms and local recurrences. Imiquimod is an immune response modifier of the imidazoquinoline class. It is the archetype drug used to control skin-field carcinogenesis. Cryotherapy, topical 5-fluorouracil, diclofenac and conventional photodynamic therapy are supposed to bring effects differing by their indications, healing rates and remission rates. The possibility of inducting a radiation recall dermatitis by some of these therapeutic modalities has not been thoroughly evaluated, and at present cannot be ruled out with confidence. [less ▲]

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See detailPre-study and in-study validation of an ultra-high pressure LC method coupled to tandem mass spectrometry for off-line determination of oxytetracycline in nasal secretions of healthy pigs.
Bimazubute, Marcel Aimé ULg; Rozet, Eric ULg; Dizier, Isabelle ULg et al

in Journal of Chromatography. B : Analytical Technologies in the Biomedical & Life Sciences (2009), 877(23), 2349-57

In order to quantify oxytetracycline (OTC) in nasal secretions of healthy pigs after intramuscular injection of OTC at doses of 10, 20 and 40 mg/kg bodyweight, an original method based on ultra-high ... [more ▼]

In order to quantify oxytetracycline (OTC) in nasal secretions of healthy pigs after intramuscular injection of OTC at doses of 10, 20 and 40 mg/kg bodyweight, an original method based on ultra-high pressure liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS) was developed and fully validated. Sample preparation consisted in protein precipitation preceded by the addition of a releasing protein reagent. Metacycline (MTC) was used as internal standard. Separation was carried out at 65 degrees C in the gradient elution mode on a short analytical column filled with Acquity BEH C(18) stationary phase. The mobile phase consisted in a mixture of water and acetonitrile containing 1 mM of oxalic acid and 0.1% (v/v) of formic acid. The triple quadrupole mass spectrometer operated in the positive electrospray ionization mode; OTC and MTC were detected using multiple reaction monitoring. The pre-study and in-study validation of this bioanalytical method was performed by applying a novel strategy based on total measurement error and accuracy profiles. The maximum risk of observing future measurements falling outside the acceptance limits during routine as well as the measurements uncertainty were also estimated. [less ▲]

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See detailL'efficacité de l'ibandronate oral mensuel est maintenue sur 5 ans : l'étude MOBILE extension long terme (ELT)
Chapurlat, R.; Felsenberg, F.; Reginster, Jean-Yves ULg

in Revue du Rhumatisme (2009)

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See detailDislocation et thématisation en français et en néerlandais - L1 et L2
Rasier, Laurent ULg

Scientific conference (2009)

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See detailMinéralogie de l’ancienne mine de plomb de La Roche-en-Ardenne (Belgique).
Blondieau, Michel; Hatert, Frédéric ULg

in Le règne minéral (2009), 88

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See detailNatural expression technology to identify bioactive compounds of medical relevance
Craig, Matthias ULg

Diverse speeche and writing (2009)

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See detailPractical feeding of sugar gliders (Petaurus breviceps)
Guillon, Leslie; Hornick, Jean-Luc ULg; Istasse, Louis ULg et al

in Mussa, P. P.; Nery, J.; Schiavone, A. (Eds.) et al Congress Proceedings 13t h Congress of the ESVCN (2009)

Communication relatant un essai d'alimentation pratique de sugar glider en captivité

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See detailLa Russie et sa nouvelle stratégie de puissance mondiale
Santander, Sebastian; Bachkatov, Nina ULg; Arès, Mathieu et al

in L'émergence de nouvelles puissances, vers un système multipolaire? (2009)

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See detailSpecies and tissue-independent rapid regulation of aromatase activity by phosphorylations.
Charlier, Thierry ULg; Harada, Nobuhiro; Ball, Gregory F. et al

in Acta Neurologica Belgica (2009)

Aromatase activity (AA) is rapidly inhibited in male quail brains, following expression of sexual behavior, activation of glutamatergic receptors or exposure to phosphorylating conditions. Questions ... [more ▼]

Aromatase activity (AA) is rapidly inhibited in male quail brains, following expression of sexual behavior, activation of glutamatergic receptors or exposure to phosphorylating conditions. Questions remain as to whether direct aromatase phosphorylation is the common key regulatory mechanism and whether these inhibitions are specific to quail hypothalamus. We now showed that AA is rapidly downregulated in quail ovary homogenates incubated in phosphorylating conditions, similarly to what is observed in hypothalamic homogenates. To understand the processes underlying this control, we expressed human aromatase in the human cell line HEK293 and 1) researched whether human aromatase can also be rapidly modulated by phosphorylations and 2) investigated more precisely the processes involved in this rapid control of activity. AA in HEK293 was rapidly inhibited following depolarization of intact cells with 100 mM KCl or in cell lysates exposed to phosphorylating conditions. Thus inhibition of AA in phosphorylating conditions is not unique to the quail hypothalamus neural environment but seems to be a general process. We are now defining the contribution of single residues of the aromatase protein to this enzymatic control. [less ▲]

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See detailIdéologies et hégémonie : la classe dirigeante au prisme des think tanks
Geuens, Geoffrey ULg

in Quaderni : la Revue de la Communication (2009), 70 ("Think tanks, experts et pouvoirs")(automne), 69-77

This article seeks to rethink the world of think tanks as a sub-space constituting the field of power; growing links of this sub-space with media industry, economy and politics being expressed and ... [more ▼]

This article seeks to rethink the world of think tanks as a sub-space constituting the field of power; growing links of this sub-space with media industry, economy and politics being expressed and consolidated through the seamless movement of certain social agents. These representatives of the financial bourgeoisie have in fact a purely instrumental relation with liberalism, their pragmatism being well accommodated with a social discourse of public regulation. In this perspective, the denunciation of think tanks as a preferred vehicle for liberal ideology ignores the role of think tanks in the construction, reproduction and dissemination of a hegemonic discourse – that of capitalism – which uses both market idolatry and State fetishism. [less ▲]

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See detailGeomorphology of streams and rivers
Bravard, J. P.; Petit, François ULg

in Encyclopedia of Inland Waters (2009)

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See detailThe International Osteoporosis Foundation: history, objectives and achievements.
Cooper, C.; Rizzoli, R.; Reginster, Jean-Yves ULg

in Osteoporosis International (2009), 20 Suppl 3

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See detailA Staging Model to Guide Psychological Interventions in Psychosis
Raballo, A.; Laroi, Frank ULg

in Psychiatric Services (2009), 60

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See detailA P2X Ion Channel-triggered NF-{kappa}B Pathway Enhances TNF-{alpha}-induced IL-8 Expression in Airway Epithelial Cells.
Theatre, Emilie ULg; Bours, Vincent ULg; Oury, Cécile ULg

in American Journal of Respiratory Cell and Molecular Biology (2009)

Extracellular ATP, acting at P2Y and P2X receptors, has recently been shown to contribute to airway inflammation. Using different epithelial cell models, this study shows that ATP promotes TNF-alpha ... [more ▼]

Extracellular ATP, acting at P2Y and P2X receptors, has recently been shown to contribute to airway inflammation. Using different epithelial cell models, this study shows that ATP promotes TNF-alpha-elicited IL-8 expression through P2X ion channel-triggered Ca(2+) entry, leading to CaMK-dependent IKK activation and binding of active p65 to IL-8 gene promoter. [less ▲]

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See detailIbandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data.
Cranney, Ann; Wells, G. A.; Yetisir, E. et al

in Osteoporosis International (2009), 20(2), 291-7

SUMMARY: This analysis was conducted to assess the effect of high versus lower doses of ibandronate on nonvertebral fractures. The results were adjusted for clinical fracture, age, and bone density. The ... [more ▼]

SUMMARY: This analysis was conducted to assess the effect of high versus lower doses of ibandronate on nonvertebral fractures. The results were adjusted for clinical fracture, age, and bone density. The treatment effect was dose-dependent. Higher doses of ibandronate significantly reduced the risk of nonvertebral fractures more effectively compared with lower doses. INTRODUCTION: The objective of this study was to assess the efficacy of different doses of ibandronate on nonvertebral fractures in a pooled analysis. METHODS: Eight randomized trials of ibandronate were reviewed for inclusion. Alternative definitions of high versus low doses based on annual cumulative exposure (ACE) were explored. A time-to-event analysis was conducted using Kaplan-Meier methodology. Hazard ratios (HR) were derived using Cox regression and adjusted for covariates. RESULTS: Combining higher ACE doses of > or = 10.8 mg (150 mg once monthly, 3 mg i.v. quarterly, and 2 mg i.v. every 2 months) versus ACE doses of 5.5 mg, from two trials, resulted in an HR 0.62 (95% CI 0.396-0.974, p = 0.038). There was a dose-response trend with increasing ACE doses (7.2-12 mg) versus ACE of 5.5 mg. CONCLUSIONS: A dose-response effect on nonvertebral fractures was observed when comparing high with low ACE doses. A significant reduction in nonvertebral fractures was noted when pooling data from trials using ACE doses of > or = 10.8 mg versus ACE < or = 7.2 mg; and with ACE > or = 10.8 mg versus ACE of 5.5 mg (38% reduction). Higher ibandronate dose levels (150 mg monthly or 3 mg i.v. quarterly) significantly reduced nonvertebral fracture risk in postmenopausal women. [less ▲]

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