References of "2009"
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See detailEffects of intraovarian application of insulin-like growth factor-1 (IGF-1) on the superovulatory response of diary cattle.
Velazquez, M. A.; Hadeler, K. G.; Beckers, Jean-François ULg et al

in Reproduction in Domestic Animals (2009), 44(S1), 38

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See detailAseptic vitrification of blastocysts from infertile patients, egg donors and after IVM
Vanderzwalmen, Pierre ULg; Ectors, Fabien ULg; Grobet, Luc ULg et al

in Reproductive Biomedicine Online (2009), 19(5), 700-707

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See detailAnthropologie et migrations africaines : une généalogie des recherches
Kuczynski; Razy, Elodie ULg

in Revue Européenne des Migrations Internationales (2009), 25(3), 79-100

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See detailImportance of steroid receptor coactivators in the modulation of steroid action on brain and behavior
Charlier, Thierry ULg

in Psychoneuroendocrinology (2009), 34

Steroid receptors such as estrogen and androgen receptors are nuclear receptors involved in the transcriptional regulation of a large number of target genes. Steroid-dependent protein expression in the ... [more ▼]

Steroid receptors such as estrogen and androgen receptors are nuclear receptors involved in the transcriptional regulation of a large number of target genes. Steroid-dependent protein expression in the brain controls a large array of biological processes including spatial cognition, copulatory behavior and neuroprotection. The discovery of a competition, or squelch- ing, between two different nuclear receptors introduced the notion that common cofactors may be involved in the modulation of transcriptional activity of nuclear receptors. These cofactors or coregulatory proteins are functionally divided into coactivators and corepressors and are involved in chromatin remodeling and stabilization of the general transcription machinery. Although a large amount of information has been collected about the in vitro function of these coregulatory proteins, relatively little is known regarding their physiological role in vivo, particularly in the brain. Our laboratory and others have demonstrated the importance of SRC-1 in the differentia- tion and activation of steroid-dependent sexual behaviors and the related neural genes. For example, we report that the inhibition of SRC-1 expression blocks the activating effects of exogenous testosterone on male sexual behaviors and increases the volume of the median preoptic area. Other coactivators are likely to be involved in the modulation in vivo of steroid receptor activity and it seems that the presence of a precise subset of coactivators could help define the phenotype of the cell by modulating a specific downstream pathway after steroid receptor activation. The very large number of coactivators and their association into preformed complexes potentially allows the determination of hundreds of different phenotypes. The study of the expression of the coactivator and their function in vivo is required to fully understand steroid action and specificity in the brain. [less ▲]

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See detailDo pictures of faces, and which ones, capture attention in the inattentional blindness paradigm?
Devue, Christel ULg; Laloyaux, Cédric ULg; Feyers, Dorothée ULg et al

in Perception (2009), 38(4), 552568

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning ... [more ▼]

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning of these stimuli rather than to their familiarity (Mack and Rock 1998). IB has mostly been investigated with schematic stimuli in previous work. In the present study, the generalisability of this finding was tested using photographic stimuli. In support to the view that faces constitute a special category of stimuli, it was found that pictures of faces resisted more to IB than pictures of common objects (Experiment 1) or than pictures of inverted faces (Experiment 2). In a third experiment, the influence of face familiarity and identity (ie the participant’s own face, a friend’s face and an unknown face) on IB rates was evaluated. Unexpectedly, no differential resistance to blindness across these three kinds of faces was found. In conclusion, picture of faces attracted attention more than pictures of objects or inverted faces in the IB paradigm. However, this effect was not dependent on face familiarity or identity. [less ▲]

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See detailAnalyse de bijoux mérovingiens en Belgique
Mathis, François ULg; Othmane, Guillaume; Vrielynck, Olivier

Conference (2009)

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See detailCellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors.
Sennino, Barbara; Kuhnert, Frank; Tabruyn, Sébastien ULg et al

in Cancer Research (2009), 69(10), 4527-36

Vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and their receptors are important targets in cancer therapy based on angiogenesis inhibition. However, it is unclear ... [more ▼]

Vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and their receptors are important targets in cancer therapy based on angiogenesis inhibition. However, it is unclear whether inhibition of VEGF and PDGF together is more effective than inhibition of either one alone. Here, we used two contrasting tumor models to compare the effects of inhibiting VEGF or PDGF alone, by adenovirally generated soluble receptors, to the effects of inhibiting both together. In RIP-Tag2 tumors, VEGF and PDGF inhibition together reduced tumor vascularity and abundance of pericytes. However, VEGF inhibition reduced tumor vascularity without decreasing pericyte density, and PDGF inhibition reduced pericytes without reducing tumor vascularity. By contrast, in Lewis lung carcinomas (LLC), inhibition of VEGF or PDGF reduced blood vessels and pericytes to the same extent as did inhibition of both together. Similar results were obtained using tyrosine kinase inhibitors AG-013736 and imatinib. In LLC, VEGF expression was largely restricted to pericytes and PDGF was largely restricted to endothelial cells, but, in RIP-Tag2 tumors, expression of both growth factors was more widespread and significantly greater than in LLC. These findings suggest that inhibition of PDGF in LLC reduced pericytes, and then tumor vessels regressed because pericytes were the main source of VEGF. The vasculature of RIP-Tag2 tumors, in which most VEGF is from tumor cells, was more resistant to PDGF inhibition. The findings emphasize the interdependence of pericytes and endothelial cells in tumors and the importance of tumor phenotype in determining the cellular effects of VEGF and PDGF inhibitors on tumor vessels. [less ▲]

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See detailEarly identification of inner pillar cells during rat cochlear development.
Thelen, Nicolas ULg; Breuskin, Ingrid ULg; Malgrange, Brigitte ULg et al

in Cell & Tissue Research (2009), 337(1), 1-14

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Here, we examine its spatio-temporal development ... [more ▼]

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Here, we examine its spatio-temporal development in rats from embryonic day 16 (E16) to E19 by using cytochemical and immunocytochemical methods at the light- and electron-microscope levels. We demonstrate that the organ of Corti develops from a non-proliferating cell zone that is located in the junctional region between two edges of the dorsal epithelium of the cochlear duct. We also reveal that the first cells to develop in this zone are the inner pillar cells, a particular type of non-sensory supporting cell, which arise in the base of the cochlear duct at the boundary between the two ridges at E16. Cell differentiation in this prosensory region continues according to a base-to-apex gradient; the inner hair cells appear in the greater epithelial ridge at E17 and the outer hair cells in the lesser epithelial ridge at E18. At E19, the various cell types of the organ of Corti are in place. Finally, we show that unlike the development of all the supporting cell types of the organ of Corti, the development of inner pillar cells within the prosensory domain seems not to involve Notch1 activation. These results highlight the central role that the inner pillar cells probably play in the development of the organ of Corti. [less ▲]

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See detailLe nouveau management public : éléments de définition et enjeu identitaire,
Schoenaers, Frédéric ULg

in Guillaume, Jean-François (Ed.) Bousculer les habitudes scolaires. Vers une gestion pédagogique des écoles secondaires (2009)

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See detailStatistical inverse analysis based on genetic algorithm and principal component analysis: Method and developments using synthetic data
Levasseur, Séverine ULg; Malécot, Yann; Boulon, Marc et al

in International Journal for Numerical and Analytical Methods in Geomechanics (2009), 33(12), 1485-1511

This study concerns the identification of parameters of soil constitutive models from geotechnical measurements by inverse analysis. To deal with the non-uniqueness of the solution, the inverse analysis is ... [more ▼]

This study concerns the identification of parameters of soil constitutive models from geotechnical measurements by inverse analysis. To deal with the non-uniqueness of the solution, the inverse analysis is based on a genetic algorithm (GA) optimization process. For a given uncertainty on the measurements, the GA identifies a set of solutions. A statistical method based on a principal component analysis (PCA) is, then, proposed to evaluate the representativeness of this set. It is shown that this representativeness is controlled by the GA population size for which an optimal value can be defined. The PCA also gives a first-order approximation of the solution set of the inverse problem as an ellipsoid. These developments are first made on a synthetic excavation problem and on a pressuremeter test. Some experimental applications are, then, studied in a companion paper, to show the reliability of the method. [less ▲]

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See detailLe jeu de l'acteur: une nouvelle méthode pour aborder l'affirmation de soi. Résultats d'une première étude portant sur trois groupes et follow-up
Delvaux, Muriel ULg; Sarto, Danielle; Roodthooft, S. et al

in Revue Francophone de Clinique Comportementale et Cognitive (2009)

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See detailModernidades múltiples y crítica social de las tecnologías
Delvenne, Pierre ULg; Erpicum, Martin ULg; Hupet, Pierre et al

in Cuadernos sobre Relaciones Internacionales, Regionalismo y Desarrollo (2009), 4(7), 65-90

Although, the links between the ideologies of progress and technological developments are often strong, we are currently observing amore and more virulent social criticism of these evolutions’ ... [more ▼]

Although, the links between the ideologies of progress and technological developments are often strong, we are currently observing amore and more virulent social criticism of these evolutions’ consequences. This paper,written by four European and Latin American researchers, addresses the way as sciences and technology issues are criticised and dealt with in Europe in the framework of “TechnologyAssessment” (TA) offices. Then, important for the authors is to consider that although TA practices proved to be efficient in a European context, such a tool may not be transferable as such in another context. Relying on the concept of “multiplemodernities”, they focus on Latin America to stress the usefulness of building an adapted local TA capacity, through an interactive process of co-construction by the practitionners and various stakeholders, including the public. [less ▲]

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See detailResemantisation in varieties of Dutch
De Vos, Lien ULg

Conference (2009)

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See detailLight as a modulator of cognitive brain function
Vandewalle, Gilles ULg; Maquet, Pierre ULg; Dijk, D. J.

in Trends in Cognitive Sciences (2009), 13(10), 429-38

Humans are a diurnal species usually exposed to light while engaged in cognitive tasks. Light not only guides performance on these tasks through vision but also exerts non-visual effects that are mediated ... [more ▼]

Humans are a diurnal species usually exposed to light while engaged in cognitive tasks. Light not only guides performance on these tasks through vision but also exerts non-visual effects that are mediated in part by recently discovered retinal ganglion cells maximally sensitive to blue light. We review recent neuroimaging studies which demonstrate that the wavelength, duration and intensity of light exposure modulate brain responses to (non-visual) cognitive tasks. These responses to light are initially observed in alertness-related subcortical structures (hypothalamus, brainstem, thalamus) and limbic areas (amygdala and hippocampus), followed by modulations of activity in cortical areas, which can ultimately affect behaviour. Light emerges as an important modulator of brain function and cognition. [less ▲]

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See detailRelaxation of strained pseudomorphic SixGe1-x layers on He-implanted Si/δ-Si:C/Si(100) substrates
Buca, D.; Minamisawa, R. A.; Trinkaus, H. et al

in Applied Physics Letters (2009), 95

In this letter we present a method to increase the efficiency of SiGe layer relaxation by He+ ion implantation and annealing. Preferential nucleation of He platelets along a 􏰀-impurity layer grown in the ... [more ▼]

In this letter we present a method to increase the efficiency of SiGe layer relaxation by He+ ion implantation and annealing. Preferential nucleation of He platelets along a 􏰀-impurity layer grown in the Si substrate below the SiGe layer results in planar localization and homogenization of dislocation loop sources inducing a more uniform distribution of misfit dislocations. We demonstrate this for a thin Si:C layer grown by reduced pressure chemical vapor deposition. The optimization of the conditions for efficient relaxation and layer quality is studied with respect to the position of the Si:C layer and the process parameters. Relaxation degrees up to 85% are obtained for Si0.77Ge0.23 layers. [less ▲]

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See detailFormation littéraire et compétences. Notes pour un débat.
Dumortier, Jean-Louis ULg

E-print/Working paper (2009)

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See detailGynaecological uses of a new class of steroids: the selective progesterone receptor modulators
Pintiaux, Axelle ULg; Chabbert-Buffet, N.; Foidart, Jean-Michel ULg

in Gynecological Endocrinology : The Official Journal of the International Society of Gynecological Endocrinology (2009), 25(2), 67-73

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on ... [more ▼]

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo. This review evaluates the actual and potential usefulness of SPRMs in gynaecology [less ▲]

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See detailSmall Scale Solar ORC system for distributed power
Orosz, Matthew; Mueller, Amy; Quoilin, Sylvain ULg et al

(2009)

A solar thermal organic Rankine cycle (ORC) can provide affordable energy supplies in remote regions. The advent of low-cost medium temperature parabolic trough collectors and ORC technology taking ... [more ▼]

A solar thermal organic Rankine cycle (ORC) can provide affordable energy supplies in remote regions. The advent of low-cost medium temperature parabolic trough collectors and ORC technology taking advantage of mass produced fluid machinery from HVAC industries are enabling developments for the production of small scale autonomous power generation units. Construction and testing of this type of system is discussed, including benchmarking of scrolls expanders (up to 75% isentropic effieiency) and the field testing of solar collectors (50% thermal efficiency at 150°C operating temperatures) with a nominal cost of $80 m-2. These results have led to the construction of a full-scale 3kW solar ORC power system designed to support a rural health clinic in Lesotho in southern Africa. [less ▲]

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