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See detailIbandronate in the management of postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Hiligsmann, Mickaël ULg; Rabenda, Véronique ULg et al

in Clinical Medicine. Therapeutics (2009), 1

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See detailThe DynaMICCS perspective. A mission for a complete and continuous view of the Sun dedicated to magnetism, space weather and space climate
Turck-Chièze, S.; Lamy, P.; Carr, C. et al

in Experimental Astronomy (2009), 23

The DynaMICCS mission is designed to probe and understand the dynamics of crucial regions of the Sun that determine solar variability, including the previously unexplored inner core, the radiative ... [more ▼]

The DynaMICCS mission is designed to probe and understand the dynamics of crucial regions of the Sun that determine solar variability, including the previously unexplored inner core, the radiative/convective zone interface layers, the photosphere/chromosphere layers and the low corona. The mission delivers data and knowledge that no other known mission provides for understanding space weather and space climate and for advancing stellar physics (internal dynamics) and fundamental physics (neutrino properties, atomic physics, gravitational moments...). The science objectives are achieved using Doppler and magnetic measurements of the solar surface, helioseismic and coronographic measurements, solar irradiance at different wavelengths and in-situ measurements of plasma/energetic particles/magnetic fields. The DynaMICCS payload uses an original concept studied by Thalès Alenia Space in the framework of the CNES call for formation flying missions: an external occultation of the solar light is obtained by putting an occulter spacecraft 150 m (or more) in front of a second spacecraft. The occulter spacecraft, a LEO platform of the mini sat class, e.g. PROTEUS, type carries the helioseismic and irradiance instruments and the formation flying technologies. The latter spacecraft of the same type carries a visible and infrared coronagraph for a unique observation of the solar corona and instrumentation for the study of the solar wind and imagers. This mission must guarantee long (one 11-year solar cycle) and continuous observations (duty cycle > 94%) of signals that can be very weak (the gravity mode detection supposes the measurement of velocity smaller than 1 mm/s). This assumes no interruption in observation and very stable thermal conditions. The preferred orbit therefore is the L1 orbit, which fits these requirements very well and is also an attractive environment for the spacecraft due to its low radiation and low perturbation (solar pressure) environment. This mission is secured by instrumental R and D activities during the present and coming years. Some prototypes of different instruments are already built (GOLFNG, SDM) and the performances will be checked before launch on the ground or in space through planned missions of CNES and PROBA ESA missions (PICARD, LYRA, maybe ASPIICS). [less ▲]

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See detailLes défauts d'implantation placentaire et leurs conséquences sur la fonction endothéliale maternelle
Foidart, Jean-Michel ULg; Noël, Agnès ULg; Chantraine, Frédéric ULg et al

in Bulletin Académique National de Médecine (2009), 193(5), 1059-66

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See detailHVDC control strategies to improve transient stability in interconnected power systems
Hazra, Jagabondhu; Phulpin, Yannick; Ernst, Damien ULg

in Proceedings of the 2009 IEEE Bucharest PowerTech (2009)

This paper presents three HVDC modulation strategies to improve transient stability in an interconnected power system. AC variables such as rotor speeds, voltage phasors, and tieline power flows are used ... [more ▼]

This paper presents three HVDC modulation strategies to improve transient stability in an interconnected power system. AC variables such as rotor speeds, voltage phasors, and tieline power flows are used as input to the controller that modifies the power flow settings through the HVDC-links. The proposed techniques are tested on the IEEE 24-Bus reliability test system and critical clearing times obtained for several contingencies are analyzed. The paper shows that HVDC modulation can lead to substantial improvement in transient stability. [less ▲]

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See detailIn situ follow-up of adsorption in activated carbon beds using X-ray microtomography
Almazan, Maria del Carmen; Léonard, Angélique ULg; Toye, Dominique ULg et al

in Kaskel, S.; Llewellyn, P.; Rodriguez-Reinoso, F. (Eds.) et al Characterisation of Porous Solids VII - Proceedings of the 8th International Symposium on the Characterisation of Porous Solids (2009)

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See detailDrug-eluting stents: a study of international practice.
Austin, David; Oldroyd, Keith G.; Holmes, David R. Jr et al

in American heart journal (2009), 158(4), 576-84

OBJECTIVE: We aimed to analyze trends in drug-eluting stents (DES) use in four international health care and regulatory settings. BACKGROUND: Accounts suggest a differential approach to DES ... [more ▼]

OBJECTIVE: We aimed to analyze trends in drug-eluting stents (DES) use in four international health care and regulatory settings. BACKGROUND: Accounts suggest a differential approach to DES internationally and recent reductions in use following reports of late stent thrombosis. Current studies of clinical practice are limited in their scope. METHODS: Data were pooled from angioplasty registries in Alberta (Canada), Belgium, Mayo Clinic (Rochester, MN), and Scotland (UK) that have routinely recorded consecutive patients treated since 2003. Trend analysis was performed to examine variations in DES use over time and by clinical subgroup. RESULTS: A total of 178,504 lesions treated between January 2003 and September 2007 were included. In the Mayo Clinic Registry, rapid adoption to a peak of 91% DES use for all lesions by late 2004 was observed. In contrast, Alberta and Scotland showed delayed adoption with lower peak DES use, respectively, 56% and 58% of lesions by early 2006. Adoption of DES in Belgium was more gradual and peak use of 35% lower than other registries. Reductions in DES use were seen in all data sets during 2006, although this varied in absolute and relative terms and by clinical subgroup. CONCLUSION: Adoption and use of DES showed wide variation in four countries. The determinants of use are complex, and it is likely that nonclinical factors predominate. Recent reductions in use may be as a consequence of publicity and concerns regarding late stent thrombosis. The optimum application of DES in clinical practice is unclear and is reflected in the degree of international variation demonstrated. [less ▲]

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See detailSocial enviroment influences aphid production of alarm pheromone
Verheggen, François ULg; Haubruge, Eric ULg; De Moraes, Consuelo M et al

in Behavioral Ecology (2009), 20(2), 283-288

In most aphid species, the volatile sesquiterpene (E)-beta-farnesene (E beta f) is released as an alarm pheromone in response to predation and is also emitted continuously at low levels. Some aphid ... [more ▼]

In most aphid species, the volatile sesquiterpene (E)-beta-farnesene (E beta f) is released as an alarm pheromone in response to predation and is also emitted continuously at low levels. Some aphid predators use E beta f as a foraging cue, suggesting that the benefits to aphids of signaling via E beta f must be weighed against the cost of increasing apparency to natural enemies. To determine whether aphids vary E beta f production in response to features of their social environment, we compared the production of E beta f by Acyrthosiphon pisum (Harris) individuals reared in isolation with that of individuals reared among conspecifics or individuals of a different aphid species, Myzus persicae. Production of E beta f by A. pisum reared in isolation was significantly lower than that of aphids reared among conspecifics or among M. persicae individuals. When we reared A. pisum individuals in isolation but exposed them to odors from an aphid colony, E beta f production was similar to that of aphids reared among conspecifics, suggesting that aphids use a volatile cue to assess their social environment and regulate their production of alarm pheromone. It is likely that this cue is E beta f itself, the only volatile compound previously found in headspace collections of A. pisum colonies. Finally, we examined the attraction of a predatory hoverfly, which uses E beta f as a foraging cue, to groups of aphids reared in isolation or among conspecifics and found that groups comprising individuals reared in isolation were significantly less attractive to the predator, suggesting that the observed variation in E beta f production may be ecologically relevant. [less ▲]

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See detailEffects of high and low inspired fractions of oxygen on horse erythrocyte membrane properties, blood viscosity and muscle oxygenation during anaesthesia
Portier, Karine; Crouzier, David; Guichardant, Michel et al

in Veterinary Anaesthesia & Analgesia (2009), 36(4), 287-298

To evaluate whether a period of hyperoxia or after a period of hypoxia produced changes attributable to reactive oxygen species in anaesthetized horses. Prospective randomized experimental study. Six ... [more ▼]

To evaluate whether a period of hyperoxia or after a period of hypoxia produced changes attributable to reactive oxygen species in anaesthetized horses. Prospective randomized experimental study. Six healthy (ASA I) geldings, aged 4.5-9.5 years and weighing 510-640 kg(-1). After 30 minutes breathing air as carrier gas for isoflurane, horses were assigned randomly to breathe air as carrier gas (CG0.21) or oxygen as carrier gas (CG1.00) for a further 90 minutes. After an interval of 1 month each horse was re-anaesthetized with the other carrier gas for the 90 minute test period. Ventilation was controlled throughout anaesthesia. Arterial blood was sampled to measure gas tensions, lactate, cholesterol, vitamin E, 4-hydroxy-alkenals, 8-epi-PGF(2 alpha), half haemolysis time, half erythrolysis time, and erythrocyte membrane fluidity. Muscle blood flow and oxygenation were evaluated by near infrared spectroscopy and coloured Doppler. After the first 30 minutes horses were hypoxemic. Subsequently the CG1.00 group became hyperoxaemic (PaO2 similar to 240 mmHg) whereas the CG0.21 group remained hypoxaemic (PaO2 similar to 60 mmHg) and had increased lactate concentration. No significant changes in vitamin E, 4-hydroxy-alkenals, or 8-epi-PGF(2 alpha) concentrations were detected. During the 90 minute test period the CG0.21 group had increased resistance to free-radical-mediated lysis in erythrocytes, whereas the CG1.00 group had slightly decreased resistance of whole blood to haemolysis. CG0.21 induced a progressive muscle deoxygenation whereas CG1.00 induced an increase in muscle oxygen saturation followed by progressive deoxygenation towards baseline. During isoflurane anaesthesia in horses, the hyperoxia induced by changing from air to oxygen induced minimal damage from reactive oxygen species. Using air as the carrier gas decreased skeletal muscle oxygenation compared with using oxygen [less ▲]

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See detailInfluence of the chemical composition on the thixoformability of steels
Pierret, Jean-Christophe ULg; Rassili, Ahmed ULg; Vaneetveld, Grégory ULg et al

in International Journal of Material Forming (2009)

This work deals with the qualification of a variety of steels for their shaping by the thixoforging process. This technology requires setting up a globular microstructure inside the material during ... [more ▼]

This work deals with the qualification of a variety of steels for their shaping by the thixoforging process. This technology requires setting up a globular microstructure inside the material during reheating to a temperature between the solidus and liquidus. As the evolution of the liquid fraction is strongly connected to the steel composition, it is useful to understand how low carbon steel could be alloyed and still thixoformable. The most critical parameter for this is the carbon content. In this study, a theoretical analysis of the phase evolution during the reheating has been performed on the MT Data software to investigate the influence of alloying elements. These first results have been confirmed by Differential Thermal Analysis and by inductive heating experiments on steel slugs. Finally, some parts have been shaped using a thixoforming tool mounted on a hydraulic press. Micrographs of reheated slugs as well as of actual parts are also presented in this paper. [less ▲]

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See detailFrom subspace learning to distance learning: a geometrical optimization approach
Meyer, Gilles ULg; Journée, Michel; Bonnabel, Silvère et al

in Proceedings of the 2009 IEEE Workshop on Statistical Signal Processing (SSP2009) (2009)

In this paper, we adopt a differential-geometry viewpoint to tackle the problem of learning a distance online. As this prob- lem can be cast into the estimation of a fixed-rank positive semidefinite (PSD ... [more ▼]

In this paper, we adopt a differential-geometry viewpoint to tackle the problem of learning a distance online. As this prob- lem can be cast into the estimation of a fixed-rank positive semidefinite (PSD) matrix, we develop algorithms that ex- ploits the rich geometry structure of the set of fixed-rank PSD matrices. We propose a method which separately updates the subspace of the matrix and its projection onto that subspace. A proper weighting of the two iterations enables to continu- ously interpolate between the problem of learning a subspace and learning a distance when the subspace is fixed. [less ▲]

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See detailAnthropologie et migrations africaines : une généalogie des recherches
Kuczynski; Razy, Elodie ULg

in Revue Européenne des Migrations Internationales (2009), 25(3), 79-100

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See detailAsthme aigu grave: une affection qui demeure redoutable.
D'Orio, Virginie ULg; Ghuysen, Alexandre ULg; Lambermont, Bernard ULg

in Revue Médicale de Liège (2009), 64(7-8), 377-81

Severe exacerbations of asthma can be life-threatening if not aggressively treated. Despite the publication of therapeutic guidelines developed by experts in this field and people education programs ... [more ▼]

Severe exacerbations of asthma can be life-threatening if not aggressively treated. Despite the publication of therapeutic guidelines developed by experts in this field and people education programs, early recognition and characterization of patients at risk for fatal asthma remain scarce. We report the case of a young lady suffering from acute exacerbation of asthma responsible for intensive care admission with long term mechanical ventilation due to the lack in initial appropriate care. [less ▲]

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See detailApplications of 3D visualization in science and engineering
Burrus, Nicolas; Hoyoux, Thomas; Verly, Jacques ULg

Conference (2009)

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See detailGestion des risques lors du transfert de méthodes analytiques
Rozet, Eric ULg; Dewe, W.; Hubert, Philippe ULg

Scientific conference (2009)

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See detailDe rol van de magistratuur in herstelgerichte praktijken
Aertsen, Ivo; Lauwaert, Katrien ULg

in Tijdschrift voor Herstelrecht (2009), 9(2), 38-51

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See detailImportance of steroid receptor coactivators in the modulation of steroid action on brain and behavior
Charlier, Thierry ULg

in Psychoneuroendocrinology (2009), 34

Steroid receptors such as estrogen and androgen receptors are nuclear receptors involved in the transcriptional regulation of a large number of target genes. Steroid-dependent protein expression in the ... [more ▼]

Steroid receptors such as estrogen and androgen receptors are nuclear receptors involved in the transcriptional regulation of a large number of target genes. Steroid-dependent protein expression in the brain controls a large array of biological processes including spatial cognition, copulatory behavior and neuroprotection. The discovery of a competition, or squelch- ing, between two different nuclear receptors introduced the notion that common cofactors may be involved in the modulation of transcriptional activity of nuclear receptors. These cofactors or coregulatory proteins are functionally divided into coactivators and corepressors and are involved in chromatin remodeling and stabilization of the general transcription machinery. Although a large amount of information has been collected about the in vitro function of these coregulatory proteins, relatively little is known regarding their physiological role in vivo, particularly in the brain. Our laboratory and others have demonstrated the importance of SRC-1 in the differentia- tion and activation of steroid-dependent sexual behaviors and the related neural genes. For example, we report that the inhibition of SRC-1 expression blocks the activating effects of exogenous testosterone on male sexual behaviors and increases the volume of the median preoptic area. Other coactivators are likely to be involved in the modulation in vivo of steroid receptor activity and it seems that the presence of a precise subset of coactivators could help define the phenotype of the cell by modulating a specific downstream pathway after steroid receptor activation. The very large number of coactivators and their association into preformed complexes potentially allows the determination of hundreds of different phenotypes. The study of the expression of the coactivator and their function in vivo is required to fully understand steroid action and specificity in the brain. [less ▲]

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