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See detailClinal differentiation during invasion: Senecio inaequidens (Asteraceae) along altitudinal gradients in Europe.
Monty, Arnaud ULg; Mahy, Grégory ULg

Poster (2009)

Plant population differentiation may play a role in decreasing the ability to predict whether, where, and when an introduced species will invade. However, few studies have addressed the level of genetic ... [more ▼]

Plant population differentiation may play a role in decreasing the ability to predict whether, where, and when an introduced species will invade. However, few studies have addressed the level of genetic change an alien species may undergo during range expansion, e.g. in response to climatic variation with altitude. In the present study, we tested the hypothesis that invasive populations of Senecio inaequidens (Asteraceae) differentiated during migration from two independent introduction sites into divergent altitudinal and climatic zones. We carried out two years of common garden experiments with eight populations from a Belgian altitudinal transect and ten populations from similar French transect. Climatic analysis revealed that the Belgian transect followed a temperature and precipitation gradient. A temperature and summer drought gradient characterized the French study site. We evaluated differentiation and clinal variation in the following characters: days to germination, days to flowering, height at maturity, final plant height and aboveground biomass. Results showed that S. inaequidens populations differentiated in growth traits during invasion. First year of experiment, regressing population growth trait means against source population altitude indicated the presence of clinal variation along both transects. Second year, similar results were found along the French transect, i.e. a reduction in height at maturity, plant height and aboveground biomass with increasing altitude. Including seed mass as a covariate did not change the outcome of the analysis. The possible evolutionary causes for the differentiation observed are discussed. [less ▲]

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See detailL'adaptation de la Stratégie européenne de sécurité. Le Livre blanc sur la sécurité et le nouveau Concept stratégique de l'OTAN : un recadrage des postures. Interactions, calendriers, ruptures
Dumoulin, André ULg

in Annuaire français de relations internationales 2009 (2009)

L’adaptation de la Stratégie européenne de sécurité fin 2008, les propositions en vue de la rédaction d’un Livre blanc européen de la sécurité et de la défense et les premières réflexions autour d’un ... [more ▼]

L’adaptation de la Stratégie européenne de sécurité fin 2008, les propositions en vue de la rédaction d’un Livre blanc européen de la sécurité et de la défense et les premières réflexions autour d’un nouveau Concept stratégique de l’OTAN provoquent maintes interrogations. Le recadrage des postures et les interactions dans les calendriers complexifient le jeu d’écritures diplomatiques. La nouvelle administration américaine, la nouvelle politique française vis-à-vis de l’OTAN et les grands défis de la PESD imposent nuance politique et nouveaux objectifs. [less ▲]

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See detailSocial security and early retirement: the relationship between workers, firms and government
Lefebvre, Mathieu ULg

E-print/Working paper (2009)

In this paper we survey a number of theoretical and empirical studies in order to propose explanations to the fall of labor force participation at older age. Starting from the largely studied effect of ... [more ▼]

In this paper we survey a number of theoretical and empirical studies in order to propose explanations to the fall of labor force participation at older age. Starting from the largely studied effect of social security schemes on labor supply, we explore the employers behavior and the role of governments in the development of early retirement schemes. We show that early retirement is the result of a global agreement between firms and government where workers have incentives to early exit the labor market due to generous non actuarial bene ts. Firms have an advantage to separate older workers because they are costly compare to young workers and governments hope that by pushing elderly into early retirement they will solve the massive unemployment problem. [less ▲]

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See detailMatrix metalloproteinase 12 silencing: A therapeutic approach to treat pathological lung tissue remodeling?
Garbacki, Nancy ULg; Di Valentin, Emmanuel ULg; Piette, Jacques ULg et al

in Pulmonary Pharmacology & Therapeutics (2009), 22(4), 267-278

Among the large matrix metalloproteinases (MMPs) family, MMP-12, also referred to as macrophage elastase, plays a significant role in chronic pulmonary pathologies characterized by an intense tissue ... [more ▼]

Among the large matrix metalloproteinases (MMPs) family, MMP-12, also referred to as macrophage elastase, plays a significant role in chronic pulmonary pathologies characterized by an intense tissue remodeling such as asthma and COPD. This review will summarize knowledge about MMP-12 structure, functions and mechanisms of activation and regulation, including potential MMP-12 modulation by microRNA. As MMP-12 is involved in many tissue remodeling diseases, efforts have been made to develop specific synthetic inhibitors. However, at this time, very few chemical inhibitors have proved to be efficient and specific to a particular MMP. The relevance of silencing MMP-12 by RNA interference is highlighted. The specificity of this approach using siRNA or shRNA and the strategies to deliver these molecules in the lung are discussed. [less ▲]

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See detailQuantum Chemistry Lab at Home: A Microsoft Windows Alternative
Olive, Gilles ULg; Riffont, David

in Journal of Chemical Education (2009), 86(5), 567

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See detailSaturn's equinoctial auroras
Nichols, J. D.; Badman, S. V.; Bunce, E. J. et al

in Geophysical Research Letters (2009), 36

We present the first images of Saturn's conjugate equinoctial auroras, obtained in early 2009 using the Hubble Space Telescope. We show that the radius of the northern auroral oval is similar to 1.5 ... [more ▼]

We present the first images of Saturn's conjugate equinoctial auroras, obtained in early 2009 using the Hubble Space Telescope. We show that the radius of the northern auroral oval is similar to 1.5 degrees smaller than the southern, indicating that Saturn's polar ionospheric magnetic field, measured for the first time in the ionosphere, is similar to 17% larger in the north than the south. Despite this, the total emitted UV power is on average similar to 17% larger in the north than the south, suggesting that field-aligned currents (FACs) are responsible for the emission. Finally, we show that individual auroral features can exhibit distinct hemispheric asymmetries. These observations will provide important context for Cassini observations as Saturn moves from southern to northern summer. Citation: Nichols, J. D., et al. (2009), Saturn's equinoctial auroras, Geophys. Res. Lett., 36, L24102, doi: 10.1029/2009GL041491. [less ▲]

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See detailDam Break Flow Modelling and Geographical Distribution of the Roughness Coefficient
Paulus, Raphaël ULg; Ernst, Julien ULg; Dewals, Benjamin ULg et al

in Proc. 33rd IAHR Congress: Water Engineering for a Sustainable Environment (pp. 2429-2436) (2009)

Dam break flow modelling is a major field of research. In order to enable risk analysis in the downstream valleys of dams, 2D numerical simulations are of prime interest. These are based on the ... [more ▼]

Dam break flow modelling is a major field of research. In order to enable risk analysis in the downstream valleys of dams, 2D numerical simulations are of prime interest. These are based on the conservative set of shallow water equations. Beyond their numerical implementation, the challenge of the computation relies on the ability to handle very huge sets of high-precision data, in order to get the highest possible accuracy, whereas the computational time must remain realistic for simulations carried out on real valleys topography. In this paper, a simulation on about 2 500 000 cells is presented. Particularly, the results are compared and discussed regarding especially the exploitation of landuse data for the roughness. Beyond the examples of validation, the relevance of the developed methodology appears to be essential in the framework of risk analysis. [less ▲]

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See detailLes noms de la langue en latin
Rochette, Bruno ULg

in Histoire Epistémologie Langage (2009), 31(2), 29-48

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See detailModélisation des systèmes biologiques
Dauby, Pierre ULg

Learning material (2009)

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See detailAcidity in Ionic liquids: from the determination of an acidity scale to the application in catalytic reactions
Olivier-Bourbigou, Hélène; Gilbert, Bernard ULg; Magna, Lionel et al

Conference (2009)

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See detailA few thoughts about representative actions
Sibony, Anne-Lise ULg

in Gheur, Charles; Petit, Nicolas (Eds.) Alternative enforcement techniques in EC Competition law: Settlement, commitments and other novel instruments (2009)

These brief remarks (originally made as a panel member commenting on other speaker's views) touch on two elementary questions regarding representative actions envisaged in the Commission's White Paper on ... [more ▼]

These brief remarks (originally made as a panel member commenting on other speaker's views) touch on two elementary questions regarding representative actions envisaged in the Commission's White Paper on Damages Actions for Breach of the EC antitrust rules. The first question adressed is "who will represent whom?". On this aspect, an analogy is drawn with the proposed directive on access to justice in environmental law matters. The second issue concerns conflicting preferences of consumers and corporate defendants regarding publicity of proceedings in which consumer's claims for damages are adjudicated. [less ▲]

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See detailCorrelation of five radioimmunoassay systems for measurement of bovine plasma pregnancy-associated glycoprotein concentrations at early pregnancy period.
Ayad, A.; Melo de Sousa, Noelita ULg; Sulon, Joseph ULg et al

in Research in Veterinary Science (2009), 86

The measurement of serum or plasma PAG concentrations is currently used as a specific method for pregnancy diagnosis in cattle. In this study, the correlation between five radioimmunoassay systems (RIA ... [more ▼]

The measurement of serum or plasma PAG concentrations is currently used as a specific method for pregnancy diagnosis in cattle. In this study, the correlation between five radioimmunoassay systems (RIA-497, RIA-706, RIA-780, RIA-809 and RIA-Pool) developed for measurement of PAG concentrations in ruminant species was investigated in plasma from pregnant Friesian Holstein females. Plasma PAG concentrations (ng/mL) measured by different RIA systems were significantly correlated between them ( 0.81; P<0.001). PAG concentrations increased significantly from Day 21 (n=27) to 30 (n=37) after AI by use of all PAG-RIA systems. From Day 30 to 80 after AI, lower PAG concentrations were observed when using the homologous system RIA-497. The addition of several proteinase inhibitors changed neither the non specific binding nor the B(0) binding to the tracer. Our results suggest that all tested PAG-RIA (RIA-497, RIA-706, RIA-780, RIA-809 and RIA-Pool) are highly correlated and can be useful to follow PAG concentrations in samples collected during the first trimester of gestation. [less ▲]

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See detailGuide des Travaux Pratiques de Biologie
Peulen, Olivier ULg; Detry, Cédric ULg; Lamour, Virginie ULg et al

Learning material (2009)

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See detailThe Social Economy: the Worldwide Making of a Third Sector
Defourny, Jacques ULg; Develtere, Patrick

in Defourny, Jacques; Develtere, Patrick; Fonteneau, Bénédicte (Eds.) et al The Worldwide Making of the Social Economy. Innovations and Changes (2009)

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See detailAlone or in concert with glucocorticoids, genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts
Relic, Biserka ULg; Zeddou, Mustapha ULg; Desoroux, Aline ULg et al

in Laboratory Investigation : Journal of Technical Methods & Pathology (2009), 89(7), 811-822

It was shown recently that synovial fibroblast transformation into adipocytes reduced the expression of interleukin-6 (IL-6) and IL-8. However, the synovial fibroblast adipogenesis was inhibited in ... [more ▼]

It was shown recently that synovial fibroblast transformation into adipocytes reduced the expression of interleukin-6 (IL-6) and IL-8. However, the synovial fibroblast adipogenesis was inhibited in inflammatory conditions induced by the tumor necrosis factor-alpha (TNF-alpha). Furthermore, adipogenesis is often accompanied by leptin production, a proinflammatory adipokine in rheumatic diseases. In this study, we tested the phytohormone genistein for adipogenic and anti-inflammatory properties on human synovial fibroblasts. Results showed that genistein was able to transform synovial fibroblasts into adipocytes that expressed perilipin-A and produced adiponectin, but not leptin. Furthermore, genistein enhanced glucocorticoid-mediated synovial fibroblast adipogenesis and, in parallel, downregulated glucocorticoid-induced leptin and leptin receptor. Endogenous and TNF-alpha-induced expressions of IL-6, IL-8, p38, p65 and C/EBP-beta were also downregulated by genistein, showing its anti-inflammatory properties. Peroxisome proliferator- activated receptor-gamma (PPAR-gamma) agonist, rosiglitazone, had a synergic effect on genistein-induced whereas the non-active tyrosine kinase inhibitor, daidzein, had a significantly inferior adipogenic activity than genistein. The Janus kinase-2 tyrosine kinase inhibitor, AG 490, mimicked the anti-leptin effect of genistein. These results showed that genistein-induced adipogenesis involves PPAR-gamma induction and tyrosine kinase inhibition. In conclusion, genistein, alone or coupled with glucocorticoids, have both adipogenic and anti-inflammatory effects on synovial fibroblasts. [less ▲]

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See detailChemical Composition of the Essential Oil of Pistacia lentiscus L. from Eastern Morocco
Amhamdi, Hassan; Aounti, Fatima; Wathelet, Jean-Paul ULg et al

in Record of Natural Products (2009), 3(2), 90-95

The essential oil from leaves of Pistacia lentiscus L., an aromatic member of the Anarcadiaceae family from Eastern Morocco, obtained by hydrodistillation, was analysed by GC-FID and GC-MS. The ... [more ▼]

The essential oil from leaves of Pistacia lentiscus L., an aromatic member of the Anarcadiaceae family from Eastern Morocco, obtained by hydrodistillation, was analysed by GC-FID and GC-MS. The constituents were identified by their mass spectra and Kovats’indices. About 104 constituents were detected in the oil. From these components, about 40 could be identified and quantified, comprising over 88.6% of the oil. The main constituents of the oil were: myrcene (39.2%), limonene (10,3) -gurjunene (7.8), germacrene (4.3%), -pinene (2.9%), muurolene (2.9), -humulene (2.6), Epi- bicyclosesquiphellandrene (2.5), -pinene (2.2). The results of this study shows both qualitative and quantitative differences with oils from P. lentiscus L of other countries. [less ▲]

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See detailForeword
Defourny, Jacques ULg

in Kerlin, Janelle A. (Ed.) Social Enterprise. A Global Comparison (2009)

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