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See detailFoy Notre-Dame : Art, Politique et Religion. Actes du colloque de Dinant (16 mai 2009)
Delfosse, Annick ULg; Dekoninck, Ralph, ; Pacco, Christian,

Book published by Société archéologique de Namur (2009)

Ouvrage collectif consacré à l'étude de la statue miraculeuse de Notre-Dame de Foy, de son sanctuaire et de son culte sous deux angles : artistique et historique. La première partie traite du sanctuaire ... [more ▼]

Ouvrage collectif consacré à l'étude de la statue miraculeuse de Notre-Dame de Foy, de son sanctuaire et de son culte sous deux angles : artistique et historique. La première partie traite du sanctuaire et des supports de dévotion. La deuxième partie dégage la signification du culte marial à Foy dans le contexte politique et religieux du XVIIe siècle et au-delà. [less ▲]

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See detailPierre-Augustin Guys à Constantinople: un regard méconnu sur le Levant à la fin du XVIIIe siècle
Famerie, Etienne ULg

in Droixhe, Daniel; Collart, Muriel (Eds.) L'"Esprit des journaux": un périodique européen au XVIIIe siècle (2009)

Guys' original approach and description of the contemporaneous Greek people, breaking a new ground in favour of the philhellenic movement in the end of 18th century

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See detailCross-reactive T cell responses in HIV CRF01_AE and B'-infected intravenous drug users: implications for superinfection and vaccines.
Promadej-Lanier, Nattawan; Thielen, Caroline ULg; Hu, Dale J et al

in AIDS Research and Human Retroviruses (2009), 25(1), 73-81

Abstract We previously observed limited cross-reactive T cell responses in two HIV-1-superinfected injection drug users (IDUs) before superinfection [Ramos A, et al.: J Virol 2002;76(15):7444-7452]. To ... [more ▼]

Abstract We previously observed limited cross-reactive T cell responses in two HIV-1-superinfected injection drug users (IDUs) before superinfection [Ramos A, et al.: J Virol 2002;76(15):7444-7452]. To elucidate the role of such responses in superinfection we examined cross-reactive T cell responses in IDUs infected with a single HIV-1 subtype. In this study, IFN-gamma ELISPOT assays were performed using recombinant vaccinia constructs and peripheral blood mononuclear cells (PBMCs) from 43 IDUs singly infected with CRF01_AE or B' from the same cohort as the superinfected IDUs. PBMCs were from time points corresponding to pre- (early) or post- (late) superinfection in the superinfected IDUs. We observed that most singly infected IDUs had cross-reactivity in samples from early (84% of CRF01_AE and 78% of B'-infected IDUs) and late (96% of CRF_01AE and 77% of B'-infected IDUs) time points. Frequent homologous reactivity at early (67% of CRF-01AE and 100% of B') and late (84% of CRF01_AE-infected and 100% of B'-infected IDUs) time points was also observed. Cross-reactive responses were predominantly to Pol and were broader and higher in CRF01_AE than in B'-infected IDUs (medians of 825 vs. 90 and 585 vs. 60 spot-forming units/10(6) PBMCs at early and late time points, respectively). Our results show that cross-reactive responses were more prevalent with greater height and breadth in singly infected IDUs than previously observed in corresponding collection time points of superinfected IDU. Thus, low or absent cross-reactivity may have contributed to the previously observed superinfections. These data are relevant for understanding superinfection and improving vaccine design. [less ▲]

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See detailInfluence of microstructure on the thermal conductivity of magnetoresistive La0.7Ca0.3MnO3/Mn3O4 manganite/insulating oxide polycrystalline bulk composites
Mucha, J.; Vertruyen, Bénédicte ULg; Misiorek, H. et al

in Journal of Applied Physics (2009), 105(6), 063501

We report the temperature dependence of the thermal conductivity kappa(T) of bulk polycrystalline composite samples containing a magnetoresistive manganite (La0.7Ca0.3MnO3) and an electrically insulating ... [more ▼]

We report the temperature dependence of the thermal conductivity kappa(T) of bulk polycrystalline composite samples containing a magnetoresistive manganite (La0.7Ca0.3MnO3) and an electrically insulating phase (Mn3O4). The sample porosity is shown to be a significant parameter affecting the experimental data: after porosity correction the curves display the characteristics of an ideal composite. A fit of the kappa(T) curves at low temperature using the Debye model enables the mean free path of phonons scattered on "boundaries" to be determined. The values are on the order of the grain size but are influenced by the grain arrangement and the presence of twins. [less ▲]

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See detailRapid synthesis of submicron crystalline barium zirconate BaZrO3 by precipitation in aqueous basic solution below 100 degrees C
Boschini, Frédéric ULg; Rulmont, André ULg; Cloots, Rudi ULg et al

in Journal of the European Ceramic Society (2009), 29(8), 1457-1462

Pure crystalline BaZrO3 powders can be produced by precipitation in highly basic aqueous solution. The influence of several synthesis parameters is studied. At high OH- concentration ([NaOH] = 20 mol/l ... [more ▼]

Pure crystalline BaZrO3 powders can be produced by precipitation in highly basic aqueous solution. The influence of several synthesis parameters is studied. At high OH- concentration ([NaOH] = 20 mol/l), it is possible to obtain the well-crystallized stoichiometric perovskite phase at relatively low temperature (similar to 80 degrees C), after a short reaction time (15 min) and without requiring any precaution to avoid the presence of CO2. This synthesis method yields spherical particles, whose size can be controlled by changing the concentration of the Ba + Zr solution. No calcination treatment is necessary since the precipitate is crystalline. Suitable choice of the synthesis parameters ([NaOH] = 20 mol/l, [Ba + Zr] = 1 mol/l, reaction time= 15 min) yields a sub-micron precipitate with excellent densification behaviour. Corrosion tests in BaO-CuO melt show that similar to 98% dense BaZrO3 obtained by sintering at 1650 degrees C for 13 h could be used for crucibles in the synthesis of YBa2Cu3O7 superconducting single crystals. (C) 2008 Elsevier Ltd. All rights reserved. [less ▲]

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See detailHybridization of short complementary PNAs to G-quadruplex forming oligonucleotides: An electrospray mass spectrometry study.
Amato, Jussara; Oliviero, Giorgia; De Pauw, Edwin ULg et al

in Biopolymers (2009), 91(4), 244-255

We investigated the interaction of the short PNA strand [acccca]-PNA with oligodeoxynucleotides containing one, two, or four tracts of TGGGGT units. Electrospray ionization mass spectrometry allowed ... [more ▼]

We investigated the interaction of the short PNA strand [acccca]-PNA with oligodeoxynucleotides containing one, two, or four tracts of TGGGGT units. Electrospray ionization mass spectrometry allowed exploring the wide variety of complex stoichiometries that were found to coexist in solution. In water, the PNA strand forms short heteroduplexes with the complementary DNA sequences, but higher-order structures are also found, with PNA(2n)*DNA(n) triplex units, culminating in precipitation at very low ionic strength. In the presence of ammonium acetate, there is a competition between PNA*DNA heteroduplex formation and DNA G-quadruplex formation. Heteroduplex formation is favored when the PNA + DNA mixture in ammonium acetate is heated and cooled at room temperature, but not if the PNA is added at room temperature to the pre-formed G-quadruplex. We also found that the short [acccca]-PNA strand binds to G-quadruplexes. (c) 2008 Wiley Periodicals, Inc. Biopolymers, 2008. [less ▲]

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See detailOARSI recommendations on knee and hip osteoarthritis: use with discernment.
Chevalier, Xavier; Henrotin, Yves ULg

in Joint Bone Spine (2009), 76(5), 455-7

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See detailMolecular classification of T-cell lymphomas.
De Leval, Laurence ULg; Bisig, Bettina ULg; Thielen, Caroline ULg et al

in Critical Reviews in Oncology/Hematology (2009)

T-cell neoplasms encompass a heterogeneous group of relatively rare disease entities. This review, focused on lymphoblastic tumors (T-ALL/LBL) and nodal-based peripheral T-cell lymphomas (PTCL ... [more ▼]

T-cell neoplasms encompass a heterogeneous group of relatively rare disease entities. This review, focused on lymphoblastic tumors (T-ALL/LBL) and nodal-based peripheral T-cell lymphomas (PTCL), summarizes recent advances in the molecular characterization of these diseases. In T-ALL/LBL, molecular subgroups delineated by gene expression profiling correlate with leukemic arrest at specific stages of normal thymocyte development and different oncogenic pathways, and seem to be of interest for prognosis prediction. Angioimmunoblastic T-cell lymphoma (AITL), one of the most common PTCL entities, comprises neoplastic cells with a molecular signature similar to normal follicular helper T cells, and this cellular derivation might account for several of the peculiar aspects of this disease. Except in ALK-positive anaplastic large cell lymphoma, defined by ALK gene fusions, chromosomal translocations are otherwise rare in PTCLs, but some recurrent rearrangements might be associated with distinct lymphoma subtypes. In PTCL, not otherwise specified (PTCL, NOS), novel molecular biomarkers of potential therapeutic interest have been recently identified. [less ▲]

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See detailQuestions d'agronomie posées par l'Académie (1772-1794)
Collart, Muriel ULg

in Hasquin, Hervé (Ed.) L'Académie impériale et royale de Bruxelles. Ses académiciens et leurs réseaux intellectuels au XVIIIe siècle (2009)

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See detailRuthenium-arene complexes bearing imidazol(in)ium-2-dithiocarboxylate ligands: Evaluation of their catalytic activity in the synthesis of enol esters
Willem, Quentin ULg; Nicks, Francois ULg; Sauvage, Xavier et al

in Journal of Organometallic Chemistry (2009), 694(25), 4049-4055

The catalytic activity of four ruthenium imidazol(in)ium-2-dithiocarboxylates was evaluated for the synthesis of vinyl esters through addition of 4-acetoxybenzoic acid to 1-hexyne, and compared to those ... [more ▼]

The catalytic activity of four ruthenium imidazol(in)ium-2-dithiocarboxylates was evaluated for the synthesis of vinyl esters through addition of 4-acetoxybenzoic acid to 1-hexyne, and compared to those of the parent ruthenium-N-heterocyclic carbene complexes and [RuCl2(p-cymene)(PPh3)] (a standard catalyst). It turned out that ruthenium imidazol(in)ium-2-dithiocarboxylates were poorly active and selective. Quantitative yields, indeed, were obtained only after extended reaction times. However, the catalytic activity could be improved significantly under microwave heating or conventional heating in a sealed tube at 160 degrees C, driving the reaction to completion in less than 4 h of reaction. [less ▲]

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See detailPlaidoyer pour une criminologie de terrain(s)
Dantinne, Michaël ULg

in Revue de Droit Pénal et de Criminologie (2009)

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See detailUrban ontologies for an improved communication in urban development projects
Teller, Jacques ULg; Cutting-Decelle, Anne-Françoise; Billen, Roland ULg

Book published by Les éditions de l'Université de Liège (2009)

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See detailOn the impact of labor market matching on regional disparities
Tharakan, Joseph ULg; Tropeano, Jean-Philippe

in Journal of Regional Science (2009), 49(1), 57-80

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See detailFrom hard to soft enforcement of EC Competition Law
Petit, Nicolas ULg; Rato, Miguel

Book published by Bruylant (2009)

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See detailThe inside-out transobturator sling for the surgical treatment of post-radical prostatectomy urinary incontinence: Short term results of a prospective study
Waltregny, David ULg; Leruth, Julie ULg; de Leval, Jean ULg

in European Urology Supplements (2009), 4(8), 336

Introduction and Objective: To prospectively evaluate the short-term safety and efficacy of a new transobturator sling procedure for treating post-radical prostatectomy (RP) stress urinary incontinence ... [more ▼]

Introduction and Objective: To prospectively evaluate the short-term safety and efficacy of a new transobturator sling procedure for treating post-radical prostatectomy (RP) stress urinary incontinence (SUI). Methods: The sling technique uses specific instruments and a polypropylene mesh with 2 arms that are passed inside to outside through the obturator foramens, pulled for compressing the bulbar urethra upward, and tied to each other across the midline. Inclusion criteria were clinically and urodynamically demonstrated SUI, positive bulbar compression test, and signed informed consent. Patients with detrusor overactivity were excluded. Baseline and followup evaluations included uroflowmetry, and continence and quality of life (QoL) questionnaires. Cure was defined by no pad use and improvement by a number of pads/d ≤ 2 and reduced by at least 50%. Complications were recorded. Results: From 04/2006 through 10/2008, 70 consecutive patients who fulfilled inclusion and exclusion criteria underwent the sling procedure using the same operative protocol. As of October 2008, 55 and 35 patients who consecutively underwent the sling procedure were expected to have a minimum followup of 6 months and 1 year, respectively. Preoperatively, 13 (24%), 25 (45%), and 17 (31%) patients were using 2, 3 to 5, and >5 pads/d, respectively. Nine and 6 patients had undergone prior surgery for SUI and/or previous pelvic irradiation, respectively. The sling procedure was preceded by an endoscopic urethrotomy in 5 (9%) patients. No perioperative complication was noted. Seven (13%) patients required suprapubic catheterization; normal voiding resumed in all 7 patients except 1 who underwent urinary diversion for radiation-induced complete anastomotic stricture. Six-month and 1-year minimum followup was available on 51 (93%) and 33 (94%) patients, respectively (Table 1). Of note, at 6 months, among the 17 patients with preoperative severe incontinence (> 5 pads/day), 9 (53%) patients were cured and 6 others (35%) were improved (1 pad/d). Overall, QoL was significantly enhanced and 85% patients were moderately to completely satisfied with the procedure. Preoperative and postoperative max flow rate and postvoid residual values were not statistically different. No sling infection, urethra erosion, persistent pain or neurological complication was observed. No sling was withdrawn or cut. Conclusions: The inside-out transobturator sling procedure appears to be safe and efficient at short term. [less ▲]

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See detailA diagnostic m-test for distributional specification of parametric conditional heteroscedasticity models for financial data
Lejeune, Bernard ULg

in Journal of Empirical Finance (2009), 16(3), 507-523

This paper proposes a convenient and generally applicable diagnostic m-test for checking the distributional specification of parametric conditional heteroscedasticity models for financial data such as the ... [more ▼]

This paper proposes a convenient and generally applicable diagnostic m-test for checking the distributional specification of parametric conditional heteroscedasticity models for financial data such as the customary Student t GARCH model. The proposed test is based on the moments of the probability integral transform of the innovations of the assumed model. Monte-Carlo evidence indicates that our test performs well both in terms of size and power. An empirical example illustrates the practical usefulness of the test and some of its possible extensions are outlined. [less ▲]

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See detailImmunobiology of reduced intensity conditioning in hematopoietic stem cell transplantation
Baron, Frédéric ULg; Sandmaier, Brenda

in Hematology education : the education program for the annual congress of the European Hematology Association (2009)

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See detailDetermination of sex and scrapie resistance genotype in preimplantation ovine embryos.
Guignot, F.; Baril, Gerard; Dupont, Francis et al

in Molecular Reproduction and Development (2009), 76(2), 183-190

The aim of this study was to test the accuracy of genotype diagnosis after pre-amplification of DNA extracted from biopsies obtained by microblade cutting of ovine embryos and to evaluate the viability of ... [more ▼]

The aim of this study was to test the accuracy of genotype diagnosis after pre-amplification of DNA extracted from biopsies obtained by microblade cutting of ovine embryos and to evaluate the viability of biopsied embryos after vitrification/warming and transfer to recipients. Sex and PrP genotypes were determined. Sex diagnosis was done by PCR amplification of ZFX/ZFY and SRY sequences after PEP-PCR while PrP genotype determination was performed after specific pre-amplification of specific target including codons 136, 154 and 171. Embryos were collected at Day 7 after oestrus. Blastocysts and expanded blastocysts were biopsied immediately after collection whereas compacted morulae were biopsied after 24 hr of in vitro culture. Eighty-nine biopsied embryos were frozen by vitrification. Fresh and vitrified whole embryos were kept as control. DNA of biopsies was extracted and pre-amplified. Sex diagnosis was efficient for 96.6% of biopsies and PrP genotyping was determined in 95.8% of codons. After embryo transfer, no significant difference was observed in lambing rate between biopsied, vitrified control and fresh embryos (54.5%, 60% and 66.6%, respectively). Embryo survival rate was not different between biopsied and whole vitrified embryos (P = 0.38). At birth, 96.7% of diagnosed sex and 95.4% of predetermined codons were correct. Lamb PrP profiles were in agreement with parental genotype. PEP-PCR coupled with sex diagnosis and nested PCR coupled with PrP genotype predetermination are very accurate techniques to genotype ovine embryo before transfer. These original results allow planning of selection of resistant genotype to scrapie and sex of offspring before transfer of cryopreserved embryo [less ▲]

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See detailPredictors of short-term outcome in brain-injured patients with disorders of consciousness.
Whyte, J.; Gosseries, Olivia ULg; Chervoneva, I. et al

in Progress in Brain Research (2009), 177

OBJECTIVES: To investigate predictors of recovery from the vegetative state (VS) and minimally conscious state (MCS) after brain injury as measured by the widely used Disability Rating Scale (DRS) and to ... [more ▼]

OBJECTIVES: To investigate predictors of recovery from the vegetative state (VS) and minimally conscious state (MCS) after brain injury as measured by the widely used Disability Rating Scale (DRS) and to explore differences in rate of recovery and predictors of recovery during inpatient rehabilitation in patients with non-traumatic (NTBI) and traumatic brain injury (TBI). DESIGN: Longitudinal observational cohort design and retrospective comparison study, in which an initial DRS score was collected at the time of study enrollment. Weekly DRS scores were recorded until discharge from the rehabilitation center for both NTBI and TBI patients. SETTING: Seven acute inpatient rehabilitation facilities in the United States and Europe with specialized programs for VS and MCS patients (the Consciousness Consortium). PARTICIPANTS: One hundred sixty-nine patients with a non-traumatic (N=50) and a traumatic (N=119) brain injury who were in the VS or MCS states. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: DRS score at 13 weeks after injury; change in DRS score over 6 weeks post-admission; and time until commands were first followed (for patients who did not show command-following at or within 2 weeks of admission). RESULTS: Both time between injury and enrollment and DRS score at enrollment were significant predictors of DRS score at week 13 post-injury but the main effect of etiology only approached significance. Etiology was however a significant predictor of the amount of recovery observed over the 6 weeks following enrollment. Time between injury and enrollment was also a good predictor of this outcome, but not DRS score at enrollment. For the time until commands were first followed, patients with better DRS scores at enrollment, and those with faster early rates of change recovered command following sooner than those with worse DRS scores or slower initial rates of change. The etiology was not a significant predictor for this last outcome. None of these predictive models explained sufficient variance to allow their use in individual clinical decision making. CONCLUSIONS: Time post-injury and DRS score at enrollment are predictors of early recovery among patients with disorders of consciousness, depending on the outcome measure chosen. Etiology was also a significant predictor in some analyses, with traumatically injured patients recovering more than those with non-traumatic injuries. However, the hypothesized interaction between etiology and time post-injury did not reach significance in any of the analyses suggesting that, within the time frame studied, the decline in prognosis with the passage of time was similar in the two groups. [less ▲]

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