References of "2009"
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See detailNeonatal health in calves - Comprehensive solutions for complex enteric disorders
Makoschey, B.; Klee, W.; Martella, V. et al

in Berliner und Munchener Tierarztliche Wochenschrift (2009), 122

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See detailLow back pain including sciatica and DISH
Rannou, François; Poiraudeau, Serge; Henrotin, Yves ULg

in Bijlsma, Johannes (Ed.) EULAR Compendium on Rheumatic Diseases (2009)

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See detailGenetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.
Villani, Alexandra-Chloé; Lemire, Mathieu; Louis, Edouard ULg et al

in PLoS ONE (2009), 4(9), 7154

BACKGROUND AND AIMS: The familial Mediterranean fever (FMF) gene (MEFV) encodes pyrin, a major regulator of the inflammasome platform controlling caspase-1 activation and IL-1beta processing. Pyrin has ... [more ▼]

BACKGROUND AND AIMS: The familial Mediterranean fever (FMF) gene (MEFV) encodes pyrin, a major regulator of the inflammasome platform controlling caspase-1 activation and IL-1beta processing. Pyrin has been shown to interact with the gene product of NLRP3, NALP3/cryopyrin, also an important active member of the inflammasome. The NLRP3 region was recently reported to be associated with Crohn's disease (CD) susceptibility. We therefore sought to evaluate MEFV as an inflammatory bowel disease (IBD) susceptibility gene. METHODOLOGY AND RESULTS: MEFV colonic mucosal gene expression was significantly increased in experimental colitis mice models (TNBS p<0.0003; DSS p<0.006), in biopsies from CD (p<0.02) and severe ulcerative colitis (UC) patients (p<0.008). Comprehensive genetic screening of the MEFV region in the Belgian exploratory sample set (440 CD trios, 137 UC trios, 239 CD cases, 96 UC cases, and 107 healthy controls) identified SNPs located in the MEFV 5' haplotype block that were significantly associated with UC (rs224217; p = 0.003; A allele frequency: 56% cases, 45% controls), while no CD associations were observed. Sequencing and subsequent genotyping of variants located in this associated haplotype block identified three synonymous variants (D102D/rs224225, G138G/rs224224, A165A/rs224223) and one non-synonymous variant (R202Q/rs224222) located in MEFV exon 2 that were significantly associated with UC (rs224222: p = 0.0005; A allele frequency: 32% in cases, 23% in controls). No consistent associations were observed in additional Canadian (256 CD trios, 91 UC trios) and Scottish (495 UC, 370 controls) sample sets. We note that rs224222 showed marginal association (p = 0.012; G allele frequency: 82% in cases, 70% in controls) in the Canadian sample, but with a different risk allele. None of the NLRP3 common variants were associated with UC in the Belgian-Canadian UC samples and no significant interactions were observed between NLRP3 and MEFV that could explain the observed flip-flop of the rs224222 risk allele. CONCLUSION: The differences in association levels observed between the sample sets may be a consequence of distinct founder effects or of the relative small sample size of the cohorts evaluated in this study. However, the results suggest that common variants in the MEFV region do not contribute to CD and UC susceptibility. [less ▲]

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See detailA discontinuous Galerkin formulation of non-linear Kirchhoff–Love shells
Noels, Ludovic ULg

in International Journal for Numerical Methods in Engineering (2009), 78(3), 296-323

Discontinuous Galerkin (DG) methods provide a means of weakly enforcing the continuity of the unknown-field derivatives and have particular appeal in problems involving high-order derivatives. This ... [more ▼]

Discontinuous Galerkin (DG) methods provide a means of weakly enforcing the continuity of the unknown-field derivatives and have particular appeal in problems involving high-order derivatives. This feature has previously been successfully exploited (Comput. Methods Appl. Mech. Eng. 2008; 197:2901-2929) to develop a formulation of linear Kirchhoff-Love shells considering only the membrane and bending responses. In this proposed one-field method - the displacements are the only unknowns, while the displacement field is continuous, the continuity in the displacement derivative between two elements is weakly enforced by recourse to a DG formulation. It is the purpose of the present paper to extend this formulation to finite deformations and non-linear elastic behaviors. While the initial linear formulation was relying on the direct linear computation of the effective membrane stress and effective bending couple-stress from the displacement field at the mid-surface of the shell, the non-linear formulation considered implies the evaluation of the general stress tensor across the shell thickness, leading to a reformulation of the internal forces of the shell. Nevertheless, since the interface terms resulting from the discontinuous Galerkin method involve only the resultant couple-stress at the edges of the shells, the extension to non-linear deformations is straightforward. [less ▲]

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See detailSubchondral bone in osteoarthritis physiopathology: state-of-the art and perspectives.
Henrotin, Yves ULg; Pesesse, Laurence ULg; Sanchez, Christelle ULg

in Bio-medical Materials & Engineering (2009), 19(4-5), 311-6

Osteoarthritis (OA) is the most common form of arthritic disease, and it is a major cause of disability and impaired quality of life in the elderly. A hallmark of the disease is progressive degeneration ... [more ▼]

Osteoarthritis (OA) is the most common form of arthritic disease, and it is a major cause of disability and impaired quality of life in the elderly. A hallmark of the disease is progressive degeneration of articular cartilage and subsequent joint space narrowing. However, OA is a complex disease not limited to cartilage degeneration, but involving also synovial membrane and subchondral bone, thereby presenting alternatives approaches for treatment. In this paper, we propose a short review of the recent advances in the understanding of the role played by subchondral bone in OA. [less ▲]

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See detailUne nouvelle macle de la pyrrhotite sur un échantillon de la mine El ,Potosi, Santa Eulalia, Chihuahua, Mexique
Philippo, Simon; Hatert, Frédéric ULg

in Le règne minéral (2009), 90

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See detailIntegrated structure and control design for mechatronic systems with configuration-dependent dynamics
Da Silva, Maíra Martins; Bruls, Olivier ULg; Desmet, Wim et al

in Mechatronics (2009), 44(9), 10161025

This paper considers the optimal design of mechatronic systems with configuration-dependent dynamics. An optimal mechatronic design requires that, among the structural and control parameters, an optimal ... [more ▼]

This paper considers the optimal design of mechatronic systems with configuration-dependent dynamics. An optimal mechatronic design requires that, among the structural and control parameters, an optimal choice has to be made with respect to design specifications in the different domains. Two main challenges are treated in this paper: the non-convex nature of the optimization problem and the difficulty in modeling serial machines with flexible components and their embedded controllers. The optimization problem is treated using the direct design strategy which considers simultaneously structural and control parameters as variables and adopts non-convex optimization algorithms. Linear time-invariant and gain-scheduling PID controllers are addressed. This methodology is exploited for the multi-objective optimization of a pick-and-place assembly robot with a gripper carried by a variable-length flexible beam. The resulting design tradeoffs between system accuracy and control efforts demonstrate the advantage of an integrated design approach for mechatronic systems with configuration-dependent dynamics. 2009 Elsevier Ltd. All rights reserved. [less ▲]

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See detailDoes implicit memory during anaesthesia persist in children?
Lopez, Ursula; Habre, w; Laurencon, M. et al

in British Journal of Anaesthesia (2009), 102(3), 37984

Background. Recent studies suggest that implicit memory (especially perceptual implicit memory) persists during adequate general anaesthesia in adults. Studies in children, however, have failed to ... [more ▼]

Background. Recent studies suggest that implicit memory (especially perceptual implicit memory) persists during adequate general anaesthesia in adults. Studies in children, however, have failed to demonstrate implicit memory during general anaesthesia, possibly because of differences in methodological design. We therefore designed a prospective study with the aim of evaluating implicit memory in children undergoing general anaesthesia, using a perceptual memory test based on the mere exposure effect, previously tested in a control group. Methods. Twelve infrequent neutral words were played 12 times in a random sequence via headphones to 36 children aged 8–12 yr during elective or emergency surgery. The children were not premedicated, and general anaesthesia was maintained with isoflurane. The word presentation started immediately after the surgical incision. Within 36 h after the stimulus presentation, the memory was assessed by using a forced-choice preference judgement task. Time constraint and word deterioration with a low-pass filter were used to prevent the subjects from utilizing intentional retrieval. The implicit memory score was obtained by calculating the proportion of target words preferred, which was compared with the chance level (0.5). Results. The percentage of correct responses given by the children was comparable with the chance level. The memory score was mean (SD) 0.48 (0.16) (95% CI 0.43–0.53). Conclusions. The use of a perceptual implicit memory test based on the mere exposure procedure in children failed to reveal any evidence of implicit memory under general anaesthesia. [less ▲]

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See detailSozialkapital und der Neue Geist des Kapitalismus - Die Ideologie des vernetzten Menschen und neue Wege der Ausbeutung
Frère, Bruno ULg

in Neue Soziale Forschungsjournal Bewegungen (2009), 22/3

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See detailA qui l'assureur doit-il payer l'indemnité d'assurance à la suite du vol d'un véhicule en leasing?
Paris, Catherine ULg

in Revue Générale des Assurances et des Responsabilités (2009)

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See detailVerslag van de workshop "Compétences terminales / Eindtermen ASO"
Rasier, Laurent ULg; De Valck, Inez

in Hiligsmann, Philippe (Ed.) Met Nederlands aan de slag / Au travail, en néerlandais (2009)

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See detailDislocation et thématisation en français et en néerlandais - L1 et L2
Rasier, Laurent ULg

Scientific conference (2009)

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See detailIngestibilité et valeur alimentaire des foins issus de prairies de haute valeur biologique
Decruyenaere, Virginie; Houba, Quentin; Stilmant, Didier et al

Article for general public (2009)

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See detailShort-term post-dispersal fate of seeds defecated by two small primate species (Saguinus mystax and Saguinus fuscicollis) in the Amazonian forest of Peru
Culot, Laurence ULg; Huynen, Marie-Claude ULg; Gérard, Paul ULg et al

in Journal of Tropical Ecology (2009), 25

Post-dispersal fate of seeds dispersed by large primates is well studied but little is known about this process in small frugivores like tamarins. This study in the Amazonian forest of Peru aimed at ... [more ▼]

Post-dispersal fate of seeds dispersed by large primates is well studied but little is known about this process in small frugivores like tamarins. This study in the Amazonian forest of Peru aimed at investigating if characteristics related to the defecation patterns of tamarins (Saguinus mystax and Saguinus fuscicollis) affected short-term post-dispersal seed fate, through secondary seed dispersal by dung beetles and removal by seed predators. Data on dung beetle activity were based on direct observations of 49 defecations while seed fate was studied using semi-controlled experiments (N = 458 for secondary dispersal and N = 398 for predation). Tamarins produce small defecations with a low number of seeds. Thirty-five per cent of defecations were visited by an average of 1.5 dung beetles that usually transport the faeces as pellets. Twenty-four per cent of seeds were buried by beetles at a mean depth of 3.5 cm. With increasing quantities of faecal matter, the probability of secondary seed dispersal increased but not the depth of burial. Seed predation pressure was low (17.6%) after 4 d and higher in faeces of S. mystax than in faeces of S. fuscicollis. Despite their small size, tamarins could be considered as high-quality seed dispersers, with a potential role for forest regeneration. [less ▲]

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See detailL'impact des transmissions familiales et scolaires sur la délinquance juvénile
Gavray, Claire ULg

in Burnay, N. (Ed.) Figures contemporaines dela transmission (2009)

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See detailFactors Affecting Plasma Pregnancy-associated Glycoprotein 1 Concentrations Throughout Gestation in High-producing Dairy Cows.
Serrano, B.; Lopez-Gatius, F.; Santolaria, P. et al

in Reproduction in Domestic Animals (2009), 44(4), 600-605

This study was designed to establish the factors, if any, which could affect plasma pregnancy-associated glycoprotein-1 (PAG-1) expression in a study population of 87 pregnant, high-producing dairy cows ... [more ▼]

This study was designed to establish the factors, if any, which could affect plasma pregnancy-associated glycoprotein-1 (PAG-1) expression in a study population of 87 pregnant, high-producing dairy cows. The factors examined were: semen providing breed (Holstein-Friesian vs Limousin), outcome of gestation (male vs female newborn, and singleton vs twin pregnancies), lactation number, milk production at pregnancy diagnosis, plasma progesterone concentration, season of gestation (warm period, March-November vs cool period, December-February), and day of gestation (40, 90, 120, 150, 180 and 210). Pregnancy was diagnosed by transrectal ultrasound on day 40 post-insemination and by palpation per rectum on days 90, 120, 150, 180 and 210. Blood samples were collected from each animal immediately before each pregnancy diagnosis. The relative contributions of the different factors on PAG-1 concentrations were evaluated by GLM repeated measures analysis of variance. No significant effects of the herd, foetal sex, milk production, lactation number and plasma progesterone concentrations were observed. In contrast, twin pregnancy, the use of Limousin semen and conception during the cool period were correlated with significantly increased plasma PAG-1 concentrations throughout gestation. Our data indicate that both cow well-being during early placental development, determined in our conditions by reduced heat stress when conception occurred in the cool season, and crossbreed pregnancies lead to improved PAG-1 production throughout the gestation period. [less ▲]

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See detailSkizze einer theoretischen Emotion
Cormann, Grégory ULg

in von Wroblewsky, Vincent (Ed.) Lebendiger Sartre (2009)

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See detailComent j'explore...- les pertes de sang d'origine vaginale dans l'enfance
Pelletier, R.; Foidart, Jean-Michel ULg; Nisolle, Michelle ULg

in Revue Médicale de Liège (2009), 64(4), 219-22

Le saignement vaginal prépubertaire est considéré comme une ménarche isolée lorsque, en l’absence de toute anomalie mise en évidence par les examens médicaux (corps étranger, tumeur, infection…), il n’y ... [more ▼]

Le saignement vaginal prépubertaire est considéré comme une ménarche isolée lorsque, en l’absence de toute anomalie mise en évidence par les examens médicaux (corps étranger, tumeur, infection…), il n’y pas de développement d’un autre caractère sexuel secondaire. Si d’autres signes pubertaires (thélarche, pubarche, pic de croissance, …) se développent, le saignement vaginal ne sera plus isolé et nous parlerons dès lors de puberté précoce vraie. C’est donc le suivi de la patiente qui nous permettra de faire le diagnostic différentiel entre ménarche précoce isolée bénigne et puberté précoce vraie engageant le pronostic statural et nécessitant une prise en charge spécifique. L’étiologie de la ménarche isolée reste indéterminée et des études complémentaires sont nécessaires. Plusieurs examens complémentaires doivent être réalisés afin d’exclure des pathologies tumorales, infectieuses, traumatiques ou encore hormonales et ceux-ci doivent être répétés lors du suivi de la patiente. [less ▲]

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See detailModelling the early phases of bone regeneration around an endosseous oral implant
Amor, N.; Geris, Liesbet ULg; Vander Sloten, J. et al

in Computer Methods in Biomechanics & Biomedical Engineering (2009), 12(4), 459-468

The objective of this study was to see whether a mathematical model of fracture healing was able to mimic bone formation around an unloaded screw-shaped titanium implant as it is well-believed that both ... [more ▼]

The objective of this study was to see whether a mathematical model of fracture healing was able to mimic bone formation around an unloaded screw-shaped titanium implant as it is well-believed that both processes exhibit many biological similarities. This model describes the spatio-temporal evolution of cellular activities, ranging from mesenchymal stem cell migration, proliferation, differentiation to bone formation, which are initiated and regulated by the growth factors present at the peri-implant site. For the simulations, a finite volume code was used and adequate initial and boundary conditions were applied. Two sets of analyses have been performed, in which either initial and boundary condition or model parameter values were changed with respect to the fracture healing model parameter values. For a number of combinations, the spatio-temporal evolution of bone density was well-predicted. However reducing cell proliferation rate and increasing osteoblast differentiation and osteogenic growth factor synthesis rates, the simulation results were in agreement with the experimental data. [less ▲]

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