References of "2009"
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See detailQualitative spatial reasoning
Billen, Roland ULg; Van de Weghe, Nico

in Thrift, Nigel; Kitchin, Rob (Eds.) International Encyclopaedia of Human Geography (2009)

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See detailBone mineral density and health related quality of life: a 3-year follow-up study of osteoportic postmenopaul women
Bruyère, Olivier ULg; De Cock, Caroline; Deroisy, Rita ULg et al

in The Open Geritric Medicine Journal (2009), 2

Objective: The objective of this study was to evaluate the relationship between change in bone mineral density (BMD) and change in health related quality of life (HRQoL) over a 3-year eriod, in patients ... [more ▼]

Objective: The objective of this study was to evaluate the relationship between change in bone mineral density (BMD) and change in health related quality of life (HRQoL) over a 3-year eriod, in patients without incident of osteoporotic fracture. Materials and Methods: Prior to the present study, two randomized controlled trials had been carried out to assess the efficacy of a new anti-osteoporotic drug. From the placebo group of those two trials, we selected for the present study 1838 osteoporotic postmenopausal women aged over 50 years, and followed their progress for a period of 3 years. BMD was measured at the lumbar spine and the proximal femur by dual-energy X-ray absorptiometry. Each patient received calcium and vitamin D supplements. HRQoL was assessed using 2 questionnaires: the generic tool Short Form 36 items (SF-36; including mental and physical components) and the specific Quality of Life Questionnaire in Osteoporosis (QUALIOST). Result: At baseline, after adjustment for body mass index (BMI), age, number of vertebral fractures and number of peripheral fractures, multivariate regression analysis showed a significant association between the lumbar BMD and the mental component of the SF-36 (p<0.001). However, the relationship was not significant with the global score of the QUALIOST (p=0.098) and the physical component of the SF-36 (p=0.051). Multivariate regressions did not show a significant relationship between HRQoL and proximal femur BMD at baseline. After 3 years of follow-up, multivariate regression analysis showed no significant association between change in lumbar BMD and the main HRQoL items (global score of the QUALIOST, physical and mental components of the SF-36; p between 0.437 and 0.942). No significant relationships were found between change in femoral BMD and change in the global score of the QUALIOST (p=0.088) or change in the mental component of the SF-36 (p=0.222). However, a significant positive association (p=0.031) appeared between change in the physical component of the SF-36 and femoral BMD change. Conclusion: In osteoporotic postmenopausal women receiving calcium and vitamin D, few relationships were found between BMD and HRQoL. However, these results were not strong enough to indicate a real clinically interesting relationship between HRQoL and BMD. Other studies would need to be performed to verify these results. [less ▲]

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See detailMagnetically controlled superconducting weak links
Van de Vondel, J.; Silhanek, Alejandro ULg; Raes, B. et al

in Applied Physics Letters (2009), 95(3),

We have designed and characterized a magnetic template which can be switched between chains of parallel and antiparallel field distribution by applying an in-plane magnetic field. The parallel field ... [more ▼]

We have designed and characterized a magnetic template which can be switched between chains of parallel and antiparallel field distribution by applying an in-plane magnetic field. The parallel field profile creates highly mobile vortex channels in a superconducting film deposited on top, reproducing the behavior of a weak link as evidenced by the presence of Shapiro steps in the current-voltage characteristics under rf excitation. The Josephson coupling can be fully suppressed by changing the field distribution to the antiparallel state. As a result, a reversible ON/OFF switch for magnetically induced weak links has been demonstrated. [less ▲]

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See detailRelations between a computerized shopping task and cognitive tests in a group of persons diagnosed with schizophrenia compared with healthy controls
Laroi, Frank ULg; Canlaire, J.; Mourad, H. et al

in Journal of the International Neuropsychological Society (2009), 16

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See detailAdditional parameters for the morphometry of angiogenesis and lymphangiogenesis in corneal flatmounts
Blacher, Silvia ULg; Detry, Benoît ULg; Bruyere, Françoise et al

in Experimental Eye Research (2009), 89(2), 274-276

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See detailComparison of accuracy of ultrasonography, progesterone and pregnancy-associated 4 glycoprotein tests for pregnancy diagnosis in semi-domesticated reindeer
Savela, Hannele; Vahtiala, S.; Lindeberg, H. et al

in Theriogenology (2009), 72

The aim of the study was to compare transrectal ultrasound with progesterone (P4) and pregnancy-associated glycoproteins (PAG) as pregnancy detection methods for semi-domesticated reindeer in field ... [more ▼]

The aim of the study was to compare transrectal ultrasound with progesterone (P4) and pregnancy-associated glycoproteins (PAG) as pregnancy detection methods for semi-domesticated reindeer in field conditions. Female reindeer (n=195) were scanned transrectally by a 7.5 MHz linear array transducer and blood sampled either in Dec 2005 (n=33), Dec 2006 (n=92) or Jan 2007 (n=70) during early- or mid-gestation. Plasma levels of P4 and PAG were assessed by RIA. Based on calving records, the sensitivity, specificity, predictive values and the overall accuracy of the three tests were calculated. The overall calving rate calculated from the calving records was 86.2%. The overall accuracy of transrectal ultrasound was 99.5%. The sensitivity and specificity of transrectal ultrasound were 99.4% and 100%, respectively. In the plasma P4 test, the threshold level of 5.5 nmol/L gave the highest overall accuracy (93.3%). The sensitivity of the P4 test decreased from 96.4% to 81.5%, when the threshold level increased from 5.0 nmol/L to 8.0 nmol/L, while the specificity remained at 85.2% over the range of these cut-off values. The overall accuracy of the plasma PAG test decreased from 96.4% to 64.1% when the plasma PAG threshold level increased from 0.5 ng/mL to 3.5 ng/mL, whereas sensitivity decreased from 99.4% to 58.3%. Specificity increased from 77.8% to 100% when the plasma PAG threshold level reached 3.0 ng/mL. Transrectal ultrasound showed higher diagnostic values than plasma P4-RIA and PAG-RIA in diagnosing pregnancy of reindeer, with the advantage that diagnoses can be made in real-time in field conditions [less ▲]

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See detailMethod for co-purification of equine neutrophil elastase and myeloperoxidase from a limited blood volume.
de la Rebière de Pouyade, Geoffroy ULg; Serteyn, Didier ULg; Deby, Ginette ULg et al

in Research in Veterinary Science (2009)

Neutrophil myeloperoxidase (MPO) and elastase can be released in severe inflammatory diseases and cause tissue injuries. Equine enzymes have already been individually purified from large blood quantities ... [more ▼]

Neutrophil myeloperoxidase (MPO) and elastase can be released in severe inflammatory diseases and cause tissue injuries. Equine enzymes have already been individually purified from large blood quantities. We describe the isolation of both enzymes from a same limited blood volume. Both MPO and elastase were extracted by crushing PMN isolated by centrifugation on a percoll-gradient from a 460ml blood collection. MPO and elastase were separated by an ionic exchange chromatography phase and further purified by gel filtration chromatography on Superdex 200 and 75, respectively. Enzymes were identified in the collected fractions by specific enzymatic assays. The final purity was verified by electrophoresis. Specific activity was improved to 19.92 and 34.3x for elastase (final yield: 340mug) and MPO (final yield: 130mug), respectively, during the procedure. Results show the possibility of isolating both enzymes from the same blood sample with a sufficient yield and purity for future studies on their implication and interaction during inflammatory diseases. [less ▲]

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See detailReproduction assistée dans l’espèce équine : collecte, évaluation, maturation et utilisations d’ovocytes équins
Deleuze, Stefan ULg; Ponthier, Jérôme ULg; Hanzen, Christian ULg

in Annales de Médecine Vétérinaire (2009), 153(1), 22-30

Malgré le faible nombre d’ovocytes équins disponibles pour la recherche, des techniques de reproduction assistée récemment développées dans cette espèce permettent maintenant de produire des embryons en ... [more ▼]

Malgré le faible nombre d’ovocytes équins disponibles pour la recherche, des techniques de reproduction assistée récemment développées dans cette espèce permettent maintenant de produire des embryons en utilisant des étalons et des juments subfertiles ou même de sauvegarder leur potentiel génétique après leur mort. Cette revue de littérature décrit les aspects cliniques de la collecte d’ovocytes ex vivo ou in vivo, leur évaluation, leur maturation in vitro et leur utilisation pour le transfert intra-folliculaire ou salpyngien et l’injection intra-cytoplasmique de spermatozoïde. [less ▲]

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See detailMultivariate analysis of cognitive profiles in Alzheimer's disease
Bastin, Christine ULg; Leclercq, Yves ULg; Collette, Fabienne ULg et al

in Proceedings of the 8th bi-annual Meeting of the Belgian Society for Neuroscience (2009)

The neuropsychological profiles of patients with early Alzheimer’s disease (AD) appear to be heterogeneous. In this study, we examined whether this heterogeneity corresponds to the existence of ... [more ▼]

The neuropsychological profiles of patients with early Alzheimer’s disease (AD) appear to be heterogeneous. In this study, we examined whether this heterogeneity corresponds to the existence of cognitively distinct subtypes of AD or rather to impairments along a continuum of performances in different cognitive domains. A large group of 187 AD patients recruited in the European project NEST-DD performed a neuropsychological battery. A factor analysis of cognitive performance identified three factors, which respectively reflected attentional/instrumental function, declarative memory and executive function. Three clustering methods were applied on the factor scores in order to explore the existence of separate groups. The clustering methods indicated that cognitive profiles among the patients were sufficiently variable to identify clusters, but there was continuity between clusters rather than clear-cut subtypes. Moreover, clusters corresponded to various combinations of relatively impaired and preserved functions, suggesting multidimensional distribution within a large population of patients. Finally, clusters of cognitive profiles were characterized by different levels of metabolism in brain regions commonly (but variably) involved or relatively preserved in AD. [less ▲]

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See detailAseptic vitrification of blastocysts from infertile patients, egg donors and after IVM
Vanderzwalmen, Pierre ULg; Ectors, Fabien ULg; Grobet, Luc ULg et al

in Reproductive Biomedicine Online (2009), 19(5), 700-707

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See detailPlanning under uncertainty, ensembles of disturbance trees and kernelized discrete action spaces
Defourny, Boris ULg; Ernst, Damien ULg; Wehenkel, Louis ULg

in Proceedings of the IEEE International Symposium on Adaptive Dynamic Programming and Reinforcement Learning (ADPRL-09) (2009)

Optimizing decisions on an ensemble of incomplete disturbance trees and aggregating their first stage decisions has been shown as a promising approach to (model-based) planning under uncertainty in large ... [more ▼]

Optimizing decisions on an ensemble of incomplete disturbance trees and aggregating their first stage decisions has been shown as a promising approach to (model-based) planning under uncertainty in large continuous action spaces and in small discrete ones. The present paper extends this approach and deals with large but highly structured action spaces, through a kernel-based aggregation scheme. The technique is applied to a test problem with a discrete action space of 6561 elements adapted from the NIPS 2005 SensorNetwork benchmark. [less ▲]

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See detailActualités en rééducation neuropsychologique: Etudes de cas
Adam, Stéphane ULg; Allain, Philippe; Aubin, Ghislaine et al

Book published by Solal (2009)

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See detailAgonistic sounds in the clownfish Amphiprion clarkii: implication of the swimbladder in the sound-producing mechanism
Colleye, Orphal ULg; Nakamura, Masaru; Parmentier, Eric ULg

Poster (2009)

Clownfishes are aggressive fishes that use sound production to defend their anemone territory. It has been shown that they produce agonistic sounds using a jaw teeth snapping. At present, this mechanism ... [more ▼]

Clownfishes are aggressive fishes that use sound production to defend their anemone territory. It has been shown that they produce agonistic sounds using a jaw teeth snapping. At present, this mechanism has highlighted the onset of the sound but has not explained yet which structure is responsible for the sound modulation. Interestingly, some acoustic features such as dominant frequency and pulse duration are directly related to fish size. Such variations are linked to a morphological constraint. Also, the existent relationship between fish size and swimbladder size implies that the swimbladder might be involved in the sound production. Sound analyses in Amphiprion clarkii showed that the experimental filling of the swimbladder with physiological liquid (NaCl 9‰) significantly modified the acoustic features. The most striking changes were a significant increase in dominant frequency and a significant decrease in pulse duration. These observations highlighted the implication of the swimbladder in sound modulation. In clownfishes, dominant frequency and pulse duration are morphologically determined signals. The swimbladder appears to modulate these acoustic features by acting as a resonant chamber. [less ▲]

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See detailRééducation de l'apathie dans la maladie d'Alzheimer par l'exploitation des domaines d'expertise du patient
Adam, Stéphane ULg

in Revue Francophone de Gériatrie et de Gérontologie (2009), 158

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See detailEvolutionary potential of the Fallopia spp. complex in Europe
Vanderhoeven, Sonia ULg; Krebs, Christine; Schaffner, Urs et al

Conference (2009)

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See detailSubchronic Alpha-Linolenic Acid Treatment Enhances Brain Plasticity and Exerts an Antidepressant Effect: A Versatile Potential Therapy for Stroke.
Blondeau, Nicolas; Nguemeni, C.; Debruyne, D. N. et al

in Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology (2009)

Omega-3 polyunsaturated fatty acids are known to have therapeutic potential in several neurological and psychiatric disorders. However, the molecular mechanisms of action underlying these effects are not ... [more ▼]

Omega-3 polyunsaturated fatty acids are known to have therapeutic potential in several neurological and psychiatric disorders. However, the molecular mechanisms of action underlying these effects are not well elucidated. We previously showed that alpha-linolenic acid (ALA) reduced ischemic brain damage after a single treatment. To follow-up this finding, we investigated whether subchronic ALA treatment promoted neuronal plasticity. Three sequential injections with a neuroprotective dose of ALA increased neurogenesis and expression of key proteins involved in synaptic functions, namely, synaptophysin-1, VAMP-2, and SNAP-25, as well as proteins supporting glutamatergic neurotransmission, namely, V-GLUT1 and V-GLUT2. These effects were correlated with an increase in brain-derived neurotrophic factor (BDNF) protein levels, both in vitro using neural stem cells and hippocampal cultures and in vivo, after subchronic ALA treatment. Given that BDNF has antidepressant activity, this led us to test whether subchronic ALA treatment could produce antidepressant-like behavior. ALA-treated mice had significantly reduced measures of depressive-like behavior compared with vehicle-treated animals, suggesting another aspect of ALA treatment that could stimulate functional stroke recovery by potentially combining acute neuroprotection with long-term repair/compensatory plasticity. Indeed, three sequential injections of ALA enhanced protection, either as a pretreatment, wherein it reduced post-ischemic infarct volume 24 h after a 1-hour occlusion of the middle cerebral artery or as post-treatment therapy, wherein it augmented animal survival rates by threefold 10 days after ischemia.Neuropsychopharmacology advance online publication, 29 July 2009; doi:10.1038/npp.2009.84. [less ▲]

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