References of "2009"
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See detailDesign procedure of a nonlinear vibration absorber using bifurcation analysis : application to the drill-string system
Viguié, Régis ULg; Kerschen, Gaëtan ULg

in ASME International Design Engineering Technical Conferences, San Diego, 2009 (2009)

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See detailFaciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer.
Ayala, Inmaculada; Giacchetti, Giada; Caldieri, Giusi et al

in Cancer Research (2009), 69(3), 747-52

Invadopodia are proteolytically active membrane protrusions that extend from the ventral surface of invasive tumoral cells grown on an extracellular matrix (ECM). The core machinery controlling ... [more ▼]

Invadopodia are proteolytically active membrane protrusions that extend from the ventral surface of invasive tumoral cells grown on an extracellular matrix (ECM). The core machinery controlling invadopodia biogenesis is regulated by the Rho GTPase Cdc42. To understand the upstream events regulating invadopodia biogenesis, we investigated the role of Fgd1, a Cdc42-specific guanine nucleotide exchange factor. Loss of Fgd1 causes the rare inherited human developmental disease faciogenital dysplasia. Here, we show that Fgd1 is required for invadopodia biogenesis and ECM degradation in an invasive cell model and functions by modulation of Cdc42 activation. We also find that Fgd1 is expressed in human prostate and breast cancer as opposed to normal tissue and that expression levels matched tumor aggressiveness. Our findings suggest a central role for Fgd1 in the focal degradation of the ECM in vitro and, for the first time, show a connection between Fgd1 and cancer progression, proposing that it might function during tumorigenesis. [less ▲]

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See detailVariability of major fatty acid contents in Luxembourg dairy cattle
Soyeurt, Hélène ULg; Arnould, Valérie ULg; Dardenne, Pierre et al

in Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production (2009)

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See detailMatrix metalloproteinase 12 silencing: A therapeutic approach to treat pathological lung tissue remodeling?
Garbacki, Nancy ULg; Di Valentin, Emmanuel ULg; Piette, Jacques ULg et al

in Pulmonary Pharmacology & Therapeutics (2009), 22(4), 267-278

Among the large matrix metalloproteinases (MMPs) family, MMP-12, also referred to as macrophage elastase, plays a significant role in chronic pulmonary pathologies characterized by an intense tissue ... [more ▼]

Among the large matrix metalloproteinases (MMPs) family, MMP-12, also referred to as macrophage elastase, plays a significant role in chronic pulmonary pathologies characterized by an intense tissue remodeling such as asthma and COPD. This review will summarize knowledge about MMP-12 structure, functions and mechanisms of activation and regulation, including potential MMP-12 modulation by microRNA. As MMP-12 is involved in many tissue remodeling diseases, efforts have been made to develop specific synthetic inhibitors. However, at this time, very few chemical inhibitors have proved to be efficient and specific to a particular MMP. The relevance of silencing MMP-12 by RNA interference is highlighted. The specificity of this approach using siRNA or shRNA and the strategies to deliver these molecules in the lung are discussed. [less ▲]

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See detailEx vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice
Foguenne, Jacques ULg; Di Stefano; Giet, Olivier ULg et al

in Haematologica (2009), 94

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in ... [more ▼]

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in engraftment of unmanipulated and cytokine-treated human cord blood CD34+ cells. [less ▲]

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See detailBranching fractions and A values in singly ionized tantalum (Ta II)
Quinet, Pascal ULg; Fivet, V.; Palmeri, P. et al

in Astronomy and Astrophysics (2009), 493

Aims. We report on the theoretical and experimental lifetimes of Ta II, and calculated branching fractions for selected transitions. Methods. The theoretical data are obtained by means of a relativistic ... [more ▼]

Aims. We report on the theoretical and experimental lifetimes of Ta II, and calculated branching fractions for selected transitions. Methods. The theoretical data are obtained by means of a relativistic Hartree-Fock method with detailed attention to correlation effects. The experimental lifetimes are measured with the time-resolved, laser-induced, fluorescence technique. Results. The calculated results are in good agreement with both previously known and new experimental lifetimes. New transition probabilities have been deduced for a set of Ta II transitions of astrophysical interest. [less ▲]

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See detailSélection d'espèces ligneuses adaptées à la fixation biologique de dunes au Niger
Laminou Manzo, Ousmane; Campanella, Bruno ULg; Paul, Roger ULg

in Geo-Eco-Trop (2009), 33

Seven woody species, of which five natives (Acacia senegal, A. raddiana, A. nilotica, Bauhinia rufescens, Balanites aegyptiaca) and two imported (Prosopis juliflora and P. chilensis) have been tested in ... [more ▼]

Seven woody species, of which five natives (Acacia senegal, A. raddiana, A. nilotica, Bauhinia rufescens, Balanites aegyptiaca) and two imported (Prosopis juliflora and P. chilensis) have been tested in terms of biological sand dunes fixation in the Southern east of Niger Republic. In nursery, species underwent a water stress by interrupting the watering during six days. Foliar hydration has been determined in order to evaluate their capacity to limit water loss. In a field experiment, species have been planted on a mechanically prefixed sand dune cord in order to test their ability for stabilization of sand dunes. Survival rates during the first three years have been calculated and height growth was measured. In nursery, results showed that, after six days of water stress, Acacia senegal, A. raddiana, P. chilensis and A. nilotica are the four species limiting the best the water losses. Results on site showed that the best combination in sand dunes fixation, in this zone, would be the association of one or the other of Prosopis (high survival rate and fast growth) with A. raddiana and/or A. nilotica (survival and growth relatively substantial and more important economic interest). [less ▲]

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See detailLarge scale experimental study of piano key weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Proc. 33rd IAHR Congress: Water Engineering for a Sustainable Environment (2009)

Piano Key Weirs (PKW) are a new type of weir, showing very good flood release capacities as well as strong economic and structural benefits. However, lacks of understanding persist about the flow ... [more ▼]

Piano Key Weirs (PKW) are a new type of weir, showing very good flood release capacities as well as strong economic and structural benefits. However, lacks of understanding persist about the flow conditions on such structures. With the goal to fill some of these lacks, a combined experimental and numerical study has been undertaken at the Laboratory of Structures Hydraulics of the University of Liege. This paper presents the goals and the scientific strategy of this research. The first results of experiments being carried out on a large physical model of PKW are also depicted. These experiments lead to characterization of the flow behavior for low heads and enable to highlight the influence of the crest thickness and the outlet slope on the release capacity. [less ▲]

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See detailWho's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior.
Tetel, M. J.; Auger, A. P.; Charlier, Thierry ULg

in Frontiers in Neuroendocrinology (2009), 30

Steroid hormones act in brain and throughout the body to regulate a variety of functions, including development, reproduction, stress and behavior. Many of these effects of steroid hormones are mediated ... [more ▼]

Steroid hormones act in brain and throughout the body to regulate a variety of functions, including development, reproduction, stress and behavior. Many of these effects of steroid hormones are mediated by their respective receptors, which are members of the steroid/nuclear receptor superfamily of transcriptional activators. A variety of studies in cell lines reveal that nuclear receptor coregulators are critical in modulating steroid receptor-dependent transcription. Thus, in addition to the availability of the hormone and the expression of its receptor, nuclear receptor coregulators are essential for efficient steroid-dependent transactivation of genes. This review will highlight the importance of nuclear receptor coregulators in modulating steroid-dependent gene expression in brain and the regulation of behavior. [less ▲]

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See detailLes marchés publics par l'analyse de cas : n°1 à 10
Durviaux, Ann-Lawrence ULg; Simar, Renaud ULg

Learning material (2009)

support écrit des travaux pratiques sous forme de casus et de propositions de résolution

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See detailCorrelation between the roughness of the substrate surface and the debonding risk
Perez, Fabien; Morency, Maxim; Bissonnette, Benoît et al

in Alexander, M. G.; Beushausen, H.-D.; Dehn, F. (Eds.) et al Concrete Repair, Rehabilitation and Retrofitting II (2009)

This paper presents the influence of substrate surface preparation on the adhesion strength of repaired beams system. Bond between new and old concrete has been the subject of a number of investigations ... [more ▼]

This paper presents the influence of substrate surface preparation on the adhesion strength of repaired beams system. Bond between new and old concrete has been the subject of a number of investigations, but in most cases, only adhesion strength was addressed. This parameter was used to estimate the durability and/or the debonding risk for repaired structure and it’s a generally accepted auditing standards. Usually, surface preparation of the substrate concrete is considered essential to achieve a durable repair because of its influence on the bond strength. To better understand debonding mechanism, in particular these related to surface preparation, roughness parameters were calculated to quantify the influence of surface preparation on the structural behaviour. Using this approach, repair beams prepared by way of four (4) concrete surface preparations were characterized. Results obtained show that repaired beams presenting a substrate with a rough surface permit to achieve a monolithic behaviour of the repaired system. Opposite structural behaviour, with large debonding, was recorded for those having smooth surface. However, all surface preparations used have promoted the same bond strength regardless the roughness of the substrate. The resulting analysis highlights the relation between roughness parameter αrough and the debonding mechanism of repaired beams. Such results will be useful to better predict the performance of concrete repairs. [less ▲]

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See detailGuideline for resuscitation in cardiac arrest after cardiac surgery.
Dunning, Joel; Fabbri, Alessandro; Kolh, Philippe ULg et al

in European Journal of Cardio - Thoracic Surgery (2009), 36(1), 3-28

The Clinical Guidelines Committee of the European Association for Cardio-Thoracic Surgery provides this professional view on resuscitation in cardiac arrest after cardiac surgery. This document was ... [more ▼]

The Clinical Guidelines Committee of the European Association for Cardio-Thoracic Surgery provides this professional view on resuscitation in cardiac arrest after cardiac surgery. This document was created using a multimodal methodology for evidence generation including the extrapolation of existing guidelines from the International Liaison Committee on Resuscitation where possible, our own structured literature reviews on issues particular to cardiac surgery, an international survey on resuscitation hosted by CTSNet and manikin simulations of potential protocols. This protocol differs from existing generic guidelines in a number of areas, the most import of which are the following: successful treatment of cardiac arrest after cardiac surgery is a multi-practitioner activity with six key roles that should be allocated and rehearsed on a regular basis; in ventricular fibrillation, three sequential attempts at defibrillation (where immediately available) should precede external cardiac massage; in asystole or extreme bradycardia, pacing (where immediately available) should precede external cardiac massage; where the above measures fail, and in pulseless electrical activity, early resternotomy is advocated; adrenaline should not be routinely given; protocols for excluding reversible airway and breathing complications and for safe emergency resternotomy are given. This guideline is subject to continuous informal review, and when new evidence becomes available. [less ▲]

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See detailDéveloppement durable des races bovines locales menacées
Bay, Elodie

Article for general public (2009)

Le projet EURECA a pour but d'assister la conservation, le développement et l'utilisation des races bovines locales, et ce en se basant sur l'étude de races locales dans 10 pays européens. Ce projet (d ... [more ▼]

Le projet EURECA a pour but d'assister la conservation, le développement et l'utilisation des races bovines locales, et ce en se basant sur l'étude de races locales dans 10 pays européens. Ce projet (d'une durée totale de 3 ans) est coordonné au niveau belge par le Faculté des Sciences Agronomiques de Gembloux. La première phase du projet, présentée dans cet article, a consisté à interroger des éleveurs et des parties prenantes à l'aide d'un formulaire standard, afin de comprendre comment s'intègre les races locales au niveau des différents intervenants. L'étude a porté sur la Pie Rouge Mixte (PRm) et la Blanc Bleu Mixte (BBm). [less ▲]

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See detailOperational Determination of Multiqubit Entanglement Classes
Bastin, Thierry ULg

Conference (2009)

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See detailPregnancy-Associated Glycoprotein D-76 kDa [Fragment] from Bubalus bubalis placenta - Access number P86375
Barbato, O.; Melo de Sousa, Noelita ULg; Barile, V. L. et al

E-print/Working paper (2009)

N-terminal microsequence obtained after purification and characterization of placental proteins in Bubalus bubalis. Proteins were submitted to SwissProt databank.

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See detailGuidelines for an integrated diagnostic approach of chronic lymphoproliferative disorders in the routine laboratory of haematology in Belgium.
Nollet, F.; Bakkus, M.; Meeus, P. et al

in Acta Clinica Belgica (2009), 64(6), 494-504

This paper summarizes the minimal workout of chronic lymphoproliferative disorders in a routine laboratory of haematology as recommended by a team of experienced laboratory supervisors in Belgium, taking ... [more ▼]

This paper summarizes the minimal workout of chronic lymphoproliferative disorders in a routine laboratory of haematology as recommended by a team of experienced laboratory supervisors in Belgium, taking into account the specific organisation of healthcare in Belgium, the innovations in the field of molecular analyses and related reimbursement. The starting point was essentially based upon clinical and/or haematological indications and it is emphasized that conclusions should be drawn in close dialogue with the clinician and experts in cytogenetics and histopathology. Reports made in the laboratory should be based upon an integration of cytomorphological, immunophenotypical and molecular data. These guidelines are not intended to be used as universal 'diagnostic pathways', but should be useful in developing local diagnostic pathways. It is well understood that this consensus, being valid anno 2009, may rapidly change with new technologies being introduced and new targets discovered. [less ▲]

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See detailProspects for Near-infrared Characterisation of Hot Jupiters with the VLTI Spectro-imager (VSI)
Renard, Stéphanie; Absil, Olivier ULg; Berger, Jean-Philippe et al

in Moorwood, A. (Ed.) Science with the VLT in the ELT Era (2009)

Since the discovery of the first exoplanet around 51 Pegasi, the study of planetary systems receives an increasing attention, with the development and test of more and more detection techniques. Among the ... [more ▼]

Since the discovery of the first exoplanet around 51 Pegasi, the study of planetary systems receives an increasing attention, with the development and test of more and more detection techniques. Among the direct detection techniques, interferometry is one of the most promising for the near future. It already provides the required angular resolution, but the dynamic range needs to be improved. The detection and characterisation of extrasolar planets is one of the main science cases of the 2nd generation VLTI Spectro-Imager instrument (VSI). The goal of this work is to study the feasibility of obtaining near-infrared spectra of bright extrasolar giant planets (EGP) with VSI. [less ▲]

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See detailEupen-Malmedy 1918-1945. Le temps des déchirures
Brüll, Christoph ULg

in Boulengier-Sedyn, Renée (Ed.) Hommage à Henri Bragard (1877-1944) (2009)

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