References of "2009"
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See detailSkizze einer theoretischen Emotion
Cormann, Grégory ULg

in von Wroblewsky, Vincent (Ed.) Lebendiger Sartre (2009)

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See detailNuclear (scintigraphic) methods and FDG-PET in rheumatoid osteoarthritis
Ribbens, Clio ULg; Hustinx, Roland ULg

in Bruno, Michael A.; Mosher, Timothy J.; Gold, Gary E. (Eds.) Arthritis in Color. Advance Imaging of Arthritis. (2009)

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See detailPertussis in adulthood: report of two cases and review of the literature.
Poirrier, Anne-Lise ULg; Gillard, Noelle ULg; Lefèbvre, Philippe ULg et al

in Laryngoscope (2009), 119(9), 1720-2

Whooping cough is resurgent in the developed world. Systematic vaccination has changed its epidemiology, with the majority of cases now primarily affecting adolescents and adults. A 46-year-old male ... [more ▼]

Whooping cough is resurgent in the developed world. Systematic vaccination has changed its epidemiology, with the majority of cases now primarily affecting adolescents and adults. A 46-year-old male physiotherapist presented with a 1-week history of bothersome cough and respiratory difficulties, and a 51-year-old man was admitted to the emergency department with a 4-week history of increasing cough and dyspnea. Polymerase chain reaction of nasopharyngeal swab were positive for Bordetella pertussis. These cases illustrate pertussis in adulthood. We review the clinical features, the prevalence, the diagnostic tools, and the management of the patients and their relatives to increase awareness of this highly contagious disease. [less ▲]

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See detailDamage and functional recovery of the Atlantic cod (Gadus morhua) inner ear hair cells following local injection of gentamicin
Faucher, Karine ULg; Aas-Hansen, Øyvind; Damsgård, Borge et al

in International Journal of Audiology (2009), 48(7), 456-464

This study addresses the ultrastructural and functional damage and subsequent recovery of the inner ear in the Atlantic cod following intrasaccular gentamicin injection. Inner ear damage was assessed ... [more ▼]

This study addresses the ultrastructural and functional damage and subsequent recovery of the inner ear in the Atlantic cod following intrasaccular gentamicin injection. Inner ear damage was assessed using SEM and measurements of AEP following 250-Hz pure-tone stimuli. Data from gentamicin-treated fish were compared with control (no injection) and sham (injection of saline) fish. Control fish had normal response thresholds associated with welldeveloped hair cell bundles in their macula sacculi. Sham fish had higher response thresholds compared with control fish during the first week post-intervention, but response thresholds were subsequently normal. Treated fish displayed significant inner ear damage associated with an increased average AEP threshold on the third day following treatment. Thereafter, inner ear tissue displayed signs of progressive regeneration until it was comparable to controls from the 14th day. Response thresholds were similar to those of control fish from the 17th day following treatment. These observations suggest that the macula sacculi of Atlantic cod can regenerate towards a near-complete functional and ultrastructural recovery within 17-21 days following ototoxic gentamicin treatment. [less ▲]

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See detailA diagnostic m-test for distributional specification of parametric conditional heteroscedasticity models for financial data
Lejeune, Bernard ULg

in Journal of Empirical Finance (2009), 16(3), 507-523

This paper proposes a convenient and generally applicable diagnostic m-test for checking the distributional specification of parametric conditional heteroscedasticity models for financial data such as the ... [more ▼]

This paper proposes a convenient and generally applicable diagnostic m-test for checking the distributional specification of parametric conditional heteroscedasticity models for financial data such as the customary Student t GARCH model. The proposed test is based on the moments of the probability integral transform of the innovations of the assumed model. Monte-Carlo evidence indicates that our test performs well both in terms of size and power. An empirical example illustrates the practical usefulness of the test and some of its possible extensions are outlined. [less ▲]

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See detailOn the impact of labor market matching on regional disparities
Tharakan, Joseph ULg; Tropeano, Jean-Philippe

in Journal of Regional Science (2009), 49(1), 57-80

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See detailIngestibilité et valeur alimentaire des foins issus de prairies de haute valeur biologique
Decruyenaere, Virginie; Houba, Quentin; Stilmant, Didier et al

Article for general public (2009)

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See detailFacteurs genetiques de l'alcoolo-dependance Revue des principales donnees de la litterature.
Pinto, Emmanuel ULg; Ansseau, Marc ULg

in Encéphale (L') (2009), 35(5), 461-9

INTRODUCTION: Alcohol dependence is a complex and multifactorial disease resulting both from neurobiological mechanisms and environmental factors. It is frequently associated with comorbid psychiatric ... [more ▼]

INTRODUCTION: Alcohol dependence is a complex and multifactorial disease resulting both from neurobiological mechanisms and environmental factors. It is frequently associated with comorbid psychiatric disorders or with specific personality or behavioral features. Although action can be taken on the environment in order to decrease the risk of the illness, current methods used to prevent or to treat this pathology show moderate efficacy: problematic consumption of ethanol in the general population as well as relapse rates under treatment in dependent patients remain indeed very high. LITERATURE FINDINGS: It is therefore of major importance to broaden our knowledge of alcohol dependence and its comorbidities so as to improve both their prevention and treatment. In this perspective, recent progress in the field of neurosciences may contribute to achieve this goal. Precisely, genetics is a promising way benefiting from many advances in genetic epidemiology, cellular and molecular biology, neuroimaging and pharmacology. In parallel with a better understanding of the neurobiology of addictions and associated behaviors, these techniques led to the identification of brain mechanisms in which a genetic variation may influence the individual vulnerability towards alcohol dependence. Moreover, there is growing evidence that alcoholism results from the interaction of genetic and environmental factors influencing both its expression and its course. Given the fact that alcohol-dependence seems highly heritable (50 to 60% of the variance in both men and women), this review assesses the role of some of the genomic regions linked with the disease, as well as the principal variants of candidate genes identified as specifically involved in the predisposition. Polymorphisms of genes influencing alcohol metabolism, GABAergic, dopaminergic and serotonergic neurotransmission seem, indeed, at stake in the development of alcohol-dependence and its related features such as personality, behavior, impulse control or craving. In the future, a better characterization of the links between genotypes and phenotypes will probably increase our ability to treat alcoholic patients. [less ▲]

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See detailAnalytical validation based on total error measurement and cut-off interpretation of a neonatal screening TSH-immunoassay.
Boemer, François ULg; Bours, Vincent ULg; Schoos, Roland ULg et al

in Journal of Chromatography. B : Analytical Technologies in the Biomedical & Life Sciences (2009), 877

To prevent the severe developmental and physical morbidities associated with congenital hypothyroidism, we developed a home-made Enzyme-Linked Immunosorbent Assay (ELISA) method to quantify Thyroid ... [more ▼]

To prevent the severe developmental and physical morbidities associated with congenital hypothyroidism, we developed a home-made Enzyme-Linked Immunosorbent Assay (ELISA) method to quantify Thyroid Stimulating Hormone (TSH) levels on newborn dried blood spots. In order to agree with actual clinical laboratory quality referential (ISO 15189), we desired to update our analytical validation protocol. For this purpose, an approach using accuracy profiles based on tolerance intervals for the total error measurement was for first time applied to an immunological assay. According to acceptance limits fixed at +/-30%, the method was found accurate over a concentration range from 17.48 to 250mIU/L. Based on 99.5 percentile of a 16,459 newborn population, cut-off was fixed at 20.1mIU/L and validated against normal and pathologic neonatal populations. Additionally, uncertainty regions around this value were obtained applying four different approaches. Finally, we demonstrated here our in-house immunological technique fulfils criterions of a neonatal screening policy. [less ▲]

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See detailOutils isotopiques : TEP et TEP/TDM
Hustinx, Roland ULg

in Dupas, Jean-Louis; Louis, Edouard; Marteau, Philippe (Eds.) Maladies inflammatoires chroniques de l'intestin. (2009)

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See detailSynthèse et propriétés tensioactives de nouveaux surfactants provenant de matières premières renouvelables.
Laurent, Pascal ULg; Razafindralambo, Hary ULg; Wathelet, Bernard ULg et al

Poster (2009)

A l'heure actuelle, le bioraffinage se présente de plus en plus comme une alternative prometteuse aux filières pétrochimiques puisqu'il vise à la fois le remplacement d'une partie du pétrole comme source ... [more ▼]

A l'heure actuelle, le bioraffinage se présente de plus en plus comme une alternative prometteuse aux filières pétrochimiques puisqu'il vise à la fois le remplacement d'une partie du pétrole comme source d'énergie et le développement de produits chimiques issus de la biomasse (végétale principalement) tels que détergents, produits phytopharmaceutiques, dissolvants, matières plastiques, etc. La valorisation de carbohydrates provenant de matières premières renouvelables fait ainsi actuellement l'objet de nombreuses recherches. Dans ce cadre, la synthèse de nouveaux tensioactifs non ioniques dérivés des acides Dglucuronique et D-galacturonique a été effectuée. [less ▲]

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See detailSynchronization in Networks of Identical Linear Systems
Scardovi, Luca; Sepulchre, Rodolphe ULg

in Automatica (2009), 45(11), 2557-2562

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See detailAdaptive Regulation of Vector Controlled Induction Motors
Jadot, Fabrice; Malrait, Francois; Moreno, Javier et al

in IEEE Transactions on Control Systems Technology (2009), 17(3),

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See detailRiemannian Metric and Geometric Mean for Positive Semidefinite Matrices of Fixed Rank
Bonnabel, Silvère; Sepulchre, Rodolphe ULg

in SIAM Journal on Matrix Analysis & Applications (2009), 31(3), 1055--1070

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See detailSpecies Differences in the Relative Densities of D1- and D2-Like Dopamine Receptor Subtypes in the Japanese Quail and Rats: An in vitro Quantitative Receptor Autoradiography Study.
Kleitz, H. K.; Cornil, Charlotte ULg; Balthazart, Jacques ULg et al

in Brain, Behavior & Evolution (2009), 73(2), 81-90

Evidence has accumulated that the regulation of male sexual behavior by dopamine might not be the same in Japanese quail (and perhaps all birds) as it is in mammals. For example, the non-selective ... [more ▼]

Evidence has accumulated that the regulation of male sexual behavior by dopamine might not be the same in Japanese quail (and perhaps all birds) as it is in mammals. For example, the non-selective dopamine receptor agonist, apomorphine (APO), facilitates male sexual behavior in rats but inhibits it in quail. Although the general organization of the dopamine system is similar in birds and mammals, it is possible that the relative distribution and/or density of binding sites are different. We therefore compared the relative densities of D1-like and D2-like receptor subtypes in Japanese quail and rats, with the use of in vitro quantitative receptor autoradiography. Brain sections from 8 male rats and 8 male quail were labeled with [(3)H]SCH-23390 and [(3)H]Spiperone. In general we found a systematic species difference in the relative density of D1- vs. D2-like receptors such that the D2/D1 ratio is higher in quail than in rats in areas, known to be important target sites for dopamine action such as striatal regions or the preoptic area, which is also associated with activation of sexual behavior. This difference might explain the variation in the behavioral effectiveness of APO in rats as compared to quail; with a higher relative density of D2-like receptors in quail, a similar dose of APO would be more likely to activate inhibitory processes in quail than in rats. [less ▲]

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See detailMetal enolates in polymer science and technology
Lecomte, Philippe ULg; Jérôme, Robert ULg

in Zabicky, Jacob (Ed.) The Chemistry of Metal Enolates (2009)

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See detailOwn-song recognition in the songbird auditory pathway: selectivity and lateralization.
Poirier, Colline; Boumans, Tiny; Verhoye, Marleen et al

in Journal of Neuroscience (2009), 29(7), 2252-8

The songbird brain is able to discriminate between the bird's own song and other conspecific songs. Determining where in the brain own- song selectivity emerges is of great importance because experience ... [more ▼]

The songbird brain is able to discriminate between the bird's own song and other conspecific songs. Determining where in the brain own- song selectivity emerges is of great importance because experience-dependent mechanisms are necessarily involved and because brain regions sensitive to self-generated vocalizations could mediate auditory feedback that is necessary for song learning and maintenance. Using functional MRI, here we show that this selectivity is present at the midbrain level. Surprisingly, the selectivity was found to be lateralized toward the right side, a finding reminiscent of the potential right lateralization of song production in zebra finches but also of own-face and own-voice recognition in human beings. These results indicate that a midbrain structure can process subtle information about the identity of a subject through experience-dependent mechanisms, challenging the classical perception of subcortical regions as primitive and nonplastic structures. They also open questions about the evolution of the cognitive skills and lateralization in vertebrates. [less ▲]

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See detailMRI in small brains displaying extensive plasticity.
Van der Linden, A.; Van Meir, V.; Boumans, T. et al

in Trends in Neurosciences (2009)

Manganese-enhanced magnetic resonance imaging (ME-MRI), blood oxygen-level-dependent functional MRI (BOLD fMRI) and diffusion tensor imaging (DTI) can now be applied to animal species as small as mice or ... [more ▼]

Manganese-enhanced magnetic resonance imaging (ME-MRI), blood oxygen-level-dependent functional MRI (BOLD fMRI) and diffusion tensor imaging (DTI) can now be applied to animal species as small as mice or songbirds. These techniques confirmed previous findings but are also beginning to reveal new phenomena that were difficult or impossible to study previously. These imaging techniques will lead to major technical and conceptual advances in systems neurosciences. We illustrate these new developments with studies of the song control and auditory systems in songbirds, a spatially organized neuronal circuitry that mediates the acquisition, production and perception of complex learned vocalizations. This neural system is an outstanding model for studying vocal learning, brain steroid hormone action, brain plasticity and lateralization of brain function. [less ▲]

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