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See detailAnalysis of the academic and professional careers of the European schools’ graduates
Van Dijk Management Consultants; Hindryckx, Geneviève ULg; Blondin, Christiane ULg

Report (2008)

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See detailEffect of aggressive interactions on aromatase activity in discrete brain regions in wild male white-crowned sparrows
Charlier, Thierry ULg; Newman, Amy EM; Soma, Kiran K

Poster (2008)

Testosterone (T) is a critical endocrine factor involved in the activation of aggressive behaviors. In many vertebrate species, circulating T levels rapidly increase after aggressive encounters during the ... [more ▼]

Testosterone (T) is a critical endocrine factor involved in the activation of aggressive behaviors. In many vertebrate species, circulating T levels rapidly increase after aggressive encounters during the breeding season. In contrast, we recently showed that circulating T concentrations did not change in white-crowned sparrows in the late breeding season after simulated territorial intrusions. We suggested that changes in local metabolism of T might be more important than changes in systemic T levels. Neural aromatization of T into 17􀀁-estradiol (E2) often mediates the physiological and behavioral actions of T. In vertebrates, aromatase is expressed in several discrete brain regions. We hypothesized that in the late breeding season, brain aromatase is rapidly modulated after aggressive interaction, leading to changes in local concentrations of E2. Wild male white-crowned sparrows were exposed to simulated territorial intrusion with song playback and decoy (STI) or control (CON) for 30 min. STI significantly increased aggressive behaviors. Birds were then caught, rapidly bled and sacrificed. Brains were collected and rapidly frozen on dry ice. We used 0.9 mm diameter punches from 300 μm coronal sections to isolate 13 different brain nuclei. Aromatase activity was analyzed in punches from the left side of the brain, while E2 was analyzed in punches from the right side of the brain. Aromatase activity was quantified by measuring the release of tritiated water during aromatization of [1􀀁-3H]-androstenedione. As expected, aromatase activity was high in the medial preoptic area, ventromedial nucleus of the hypothalamus, hippocampus, bed nucleus of the stria terminalis, nucleus taeniae of the amygdala, and caudomedial nidopallium. Aromatase activity was low in the medial magnocellular nucleus of anterior nidopallium, HVC, Area X, nucleus robustus of the arcopallium, optic lobes, periaqueductal gray and cerebellum. Aromatase activity was not different between the STI and CON groups in any region. There were no significant correlations between aromatase activity and aggressive behaviors or endocrine measures (plasma T, progesterone, corticosterone and corticosteroid binding globulin). These data provide no evidence for rapid modulation of brain aromatase activity following aggressive interactions. It is however possible that aromatase activity is more rapidly modulated (e.g. within 5 min) and these changes were not observed in our 30 min paradigm. We are currently investigating whether local E2 is affected by aggressive interactions. [less ▲]

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See detailSavoir rechercher et interroger : les repères méthodologiques
Pochet, Bernard ULg

in Noël, Elisabeth (Ed.) Ressources Electroniques pour les Etudiants, la Recherche et l'Enseignement (REPERE) (2008)

REPERE n’est pas une publication très ancienne, puisqu’elle a été créée en 2003 sous sa forme électronique, et est sortie pour la première fois en 2005 sous forme papier. Et pourtant, à l’aune du temps de ... [more ▼]

REPERE n’est pas une publication très ancienne, puisqu’elle a été créée en 2003 sous sa forme électronique, et est sortie pour la première fois en 2005 sous forme papier. Et pourtant, à l’aune du temps de l’Internet, une refonte de ses contenus était en grande partie nécessaire. En effet, ces dernières années ont vu de nombreuses évolutions, qui, sans révolutionner la recherche documentaire, l’ont modifié, en particulier pour les ressources électroniques. Ainsi, si Google fête à peine ses 10 ans en septembre 2008, cette décennie a été celle de son ascension, proposant sans cesse de nouvelles fonctionnalités, parfois discrètes. Google book search a, à une époque, fait couler beaucoup d’encre, mais Google Scholar, dans l’ombre du géant, prenait une place peut-être plus dangereuse, en tout cas en ce qui concerne la recherche d’information scientifique. De nos jours, la recherche d’information ne peut plus se penser sans Google, même si Google doit être dépassé et ne peut rester l’unique outil. Le web 2.0, terme certes galvaudé, reflète aussi une autre évolution de l’Internet, dans ce qu’il renforce l’aspect collaboratif et participatif de tous les internautes. La production d’information a changé, ainsi que son accès, et donc sa recherche. Les professionnels de l’information ont très vite intégré ces changements dans leurs formations, à travers les supports pédagogiques proposés par les URFIST et les Services communs de la documentation, ainsi que par les nombreuses formations dispensées. La notion d’éducation à l’information, de culture informationnelle est maintenant répandue au-delà de la simple sphère bibliothéconomique. Aussi, cette nouvelle version de REPERE reflète ces évolutions, et intègre de nouveaux outils. Certains chapitres ont été juste actualisés, d’autres complètement refondus, enfin de nouvelles parties ont été ajoutées, sur le besoin d’information ou le plagiat, pour ne pas les citer toutes. Nous espérons que cette brochure réactualisée saura être une première réponse à grands nombres de vos questions. N’hésitez pas à nous faire part de vos remarques, à nous signaler comment vous utilisez cette brochure et si elle répond à vos besoins. Nous en tiendrons compte pour la prochaine version. [less ▲]

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See detailComment diviser huit en trois parts égales ? De l'anecdote au récit à énigme dans la tradition arabe
Bauden, Frédéric ULg

in Bauden, Frédéric; Chraïbi, Aboubakr; Ghersetti, Antonella (Eds.) Le Répertoire narratif arabe médiéval: transmission et ouverture. Actes du colloque international (Université de Liège, 15-17 septembre 2005) (2008)

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See detailA cross-sectional evaluation of adiponectin plasma levels in patients with schizophrenia and schizoaffective disorder.
Hanssens, Linda; van Winkel, Ruud; Wampers, Martien et al

in Schizophrenia Research (2008), 106(2-3), 308-14

BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia, diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in schizophrenic patients. The ... [more ▼]

BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia, diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in schizophrenic patients. The underlying mechanism, however, is poorly understood. Adiponectin is a recently identified adipocyte-derived protein, with low adiponectin levels being associated with metabolic abnormalities such as obesity, insulin resistance and type 2 diabetes. METHODS: Fasting adiponectin levels were assessed in a cross-sectional sample of 386 patients with schizophrenia or schizoaffective disorder. All patients were on monotherapy of second-generation antipsychotics (SGA) and underwent an extensive metabolic screening including an oral glucose tolerance test (OGTT). RESULTS: Adiponectin plasma levels were inversely correlated with BMI, and differed significantly between patients with normal weight, overweight or obesity (p<0.05). Patients who met criteria for the metabolic syndrome, according to adapted National Cholesterol Educational Program - Adult Treatment Panel criteria (NCEP-ATP III) (29.3%), had significantly lower adiponectin levels than patients not meeting metabolic syndrome criteria (p<0.0001). Patients without glucose abnormalities (78%) had significantly higher adiponectin levels than patients with diabetes (5.7%) (p<0.05). After controlling for components of metabolic syndrome and sex, antipsychotic medication independently influenced adiponectin levels (p<0.0001), with the lowest mean levels in patients on clozapine and olanzapine. CONCLUSIONS: Adiponectin levels in schizophrenic patients mirror what is observed in the general population, with the lowest levels in the most metabolically comprised subjects. However, antipsychotic medication may also influence adiponectin regulation independently, a finding that should be confirmed in longitudinal studies. [less ▲]

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See detailAphid-ant mutualism: How do aphids focus ant foraging?
Verheggen, François ULg; Detrain, Claire; Diez, Lise et al

Conference (2008)

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See detailModelling the impact of wind turbines on the visual attractivity of landscapes at a regional scale
Van Rompaey, A.; Vanderheyden, V.; Schmitz, Serge ULg

in European Wind Energy Conference & Exhibition : Brussels Expo 31 March-3 April 2008 (2008)

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See detailConception de barrages mobiles et barrières anti-tempêtes
Rigo, Philippe ULg; INCOM WG26

Book published by AIPCN - Rapport 101-2008 (2008)

State of art dans le domaine du contôle des eaux dans les voies navigables (barrages mobiles et barrières marée tempête). Le rapport complet est disponible via http://www.pianc.org/ ou contacter Ph.rigo ... [more ▼]

State of art dans le domaine du contôle des eaux dans les voies navigables (barrages mobiles et barrières marée tempête). Le rapport complet est disponible via http://www.pianc.org/ ou contacter Ph.rigo@ulg.ac.be [less ▲]

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See detailToll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel.
Tichomirowa, Maria A.; Theodoropoulou, Marily; Daly, Adrian ULg et al

in International Journal of Cancer = Journal International du Cancer (2008), 123(8), 1956-63

Meningiomas are the second most common type of brain and CNS tumors by histology. Surgery and radiotherapy are main treatment options, but meningiomas may be impossible to adequately resect or may regrow ... [more ▼]

Meningiomas are the second most common type of brain and CNS tumors by histology. Surgery and radiotherapy are main treatment options, but meningiomas may be impossible to adequately resect or may regrow after surgery. In spite of many experimental attempts, there is no generally accepted chemotherapeutic approach. We have studied in a series of meningiomas the expression of the Toll-like receptor 4 (TLR4), which apart from its major role as a key factor of the innate immune system, is believed to play a role in tumorigenesis. All meningiomas studied expressed TLR4 mRNA and protein at variable degree. Paclitaxel, a ligand of TLR4, exhibited a dose- and time-dependent growth suppression in both monolayer and spheroid meningioma cell cultures. The knockdown of TLR4 with siRNA in meningioma cell cultures abrogated the inhibitory effect of paclitaxel. The suppressive action of paclitaxel on meningioma cell growth was enhanced in the presence of fluvastatin or the mitogen-actvated protein kinase (ERK1/2) inhibitor PD98059. At least part of the growth suppressive effect was mediated by the induction of apoptosis in meningioma cells by paclitaxel alone or in combination with fluvastatin. In conclusion, our in vitro results suggest that paclitaxel alone or in combination with other inhibitors of cell growth (statins, MAPK inhibitors) could provide a potential tool for the treatment of TLR4 expressing meningiomas. [less ▲]

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See detailValidation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative
Rousseau, Anne ULg; Chiap, Patrice ULg; Ivanyi, Robert et al

in Journal of Chromatography. A (2008), 1204(2), 219-225

Nonaqueous capillary electrophoresis (NACE) was successfully applied to the enantiomeric purity determination of R-flurbiprofen using 6-monodeoxy-6-mono(2-hydroxy)propylamino-beta-cyclodextrin (IPA-beta ... [more ▼]

Nonaqueous capillary electrophoresis (NACE) was successfully applied to the enantiomeric purity determination of R-flurbiprofen using 6-monodeoxy-6-mono(2-hydroxy)propylamino-beta-cyclodextrin (IPA-beta-CD) as chiral selector. The nonaqueous BGE was made up of 20 mM IPA-beta-CD, 20 mM ammonium camphorsulfortate and 40 mM ammonium acetate in methanol. Flufenamic acid was selected as internal standard. The CE method was carefully optimized in order to prevent the adsorption of the cationic CD onto the capillary wall, and therefore, to avoid loss of peak efficiency and enantioresolution. To achieve this goal, the addition of ammonium camphorsulfonate was found to be necessary. In the selected conditions, the determination of 0.1% of S-flurbiprofen in R-flurbiprofen could be performed using the method of standard additions. The NACE method was then fully validated by applying a novel strategy using accuracy profiles. (c) 2008 Elsevier B.V. All rights reserved. [less ▲]

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See detailThe global biogeography of semi-arid periodic vegetation patterns.
Deblauwe, V; Barbier, N; Couteron, P et al

in Global Ecology & Biogeography (2008), 17(6), 715-723

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See detailla commission Lumumba
Raxhon, Philippe ULg

in Dard, Olivier; Lefeuvre, Daniel (Eds.) L'Europe face à son passé colonial (2008)

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See detailRequête unilatérale et indemnité de procédure
Boularbah, Hakim ULg

in Journal des Tribunaux (2008)

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See detail"Suicidi" e "resistenze" intellettuali. Memoria della deportazione e della carcerazione : Affinati tra Campo del sangue e Un teologo contro Hitler
Curreri, Luciano ULg

in Serkowska, Hannah (Ed.) Tra storia e immaginazione: si raccontano scrittori ebrei di lingua italiana (2008)

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See detailPersistent organochlorine pollutants, dioxins and polychlorinated biphenyls
Scippo, Marie-Louise ULg; Eppe, Gauthier ULg; Saegerman, Claude ULg et al

in Contaminant and Residue Analysis, Comprehensive Analytical Chemistry of Elsevier (2008)

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See detailRetraite et chômage: les jeunes bénéficient-ils des préretraites ?
Lefebvre, Mathieu ULg

in Reflets et Perspectives de la Vie Economique (2008), XLVII(3), 7-16

Dans cet article, nous décrivons les principaux changements survenus dans l’accès aux préretraites au cours du temps et nous étudions la relation entre la chute conséquente du taux d’activité des ... [more ▼]

Dans cet article, nous décrivons les principaux changements survenus dans l’accès aux préretraites au cours du temps et nous étudions la relation entre la chute conséquente du taux d’activité des travailleurs âgés et le chômage des plus jeunes. Nos résultats vont à l’encontre de l’idée souvent émise selon laquelle les préretraites seraient bénéfiques à l’emploi des jeunes. [less ▲]

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See detailA note on longevity enhancing investment
Eeckhoudt, Louis; Pestieau, Pierre ULg

in Economics Letters (2008)

We argue that risk averse individuals prefer to increase their longevity in the direction of rectangularization of the survival curve instead of an upward shift of that curve. Risk aversion is measured by ... [more ▼]

We argue that risk averse individuals prefer to increase their longevity in the direction of rectangularization of the survival curve instead of an upward shift of that curve. Risk aversion is measured by the concept of fear of ruin. [less ▲]

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