Stress oxydant et antioxydants: mythes et réalités.
Defraigne, Jean-Olivier ; Pincemail, Joël
in Revue Médicale de Liège (2008), 63Detailed reference viewed: 82 (13 ULg)
Études régionales et fédérales : nouvelles perspectives
; Perrin, Nathalie ;
in Fédéralisme - Régionalisme (2008), 8(2),Detailed reference viewed: 20 (2 ULg)
Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up.
; ; et al
in Journal of Infectious Diseases (2008), 197(8), 1145-55
BACKGROUND AND METHODS: The SMART study compared 2 strategies for using antiretroviral therapy-drug conservation (DC) and viral suppression (VS)-in 5,472 human immunodeficiency virus (HIV)-infected ... [more ▼]
BACKGROUND AND METHODS: The SMART study compared 2 strategies for using antiretroviral therapy-drug conservation (DC) and viral suppression (VS)-in 5,472 human immunodeficiency virus (HIV)-infected patients with CD4+ cell counts >350 cells/microL. Rates and predictors of opportunistic disease or death (OD/death) and the relative risk (RR) in DC versus VS groups according to the latest CD4+ cell count and HIV RNA level are reported. RESULTS: During a mean of 16 months of follow-up, DC patients spent more time with a latest CD4+ cell count <350 cells/microL (for DC vs. VS, 31% vs. 8%) and with a latest HIV RNA level >400 copies/mL (71% vs. 28%) and had a higher rate of OD/death (3.4 vs. 1.3/100 person-years) than VS patients. For periods of follow- up with a CD4+ cell count <350 cells/microL, rates of OD/death were increased but similar in the 2 groups (5.7 vs. 4.6/100 person-years), whereas the rates were higher in DC versus VS patients (2.3 vs. 1.0/100 person-years; RR, 2.3 [95% confidence interval, 1.5-3.4]) for periods with the latest CD4+ cell count >or= 350 cells/microL-an increase explained by the higher HIV RNA levels in the DC group. CONCLUSIONS: The higher risk of OD/death in DC patients was associated with (1) spending more follow-up time with relative immunodeficiency and (2) living longer with uncontrolled HIV replication even at higher CD4+ cell counts. Ongoing HIV replication at a given CD4+ cell count places patients at an excess risk of OD/death. [less ▲]Detailed reference viewed: 94 (1 ULg)
Study of heat and mass transfer in porous media: application to packed-bed drying
Bennamoun, Lyes ;
in Fluid Dynamics and Materials Processing (2008), 4(4), 221-230Detailed reference viewed: 8 (3 ULg)
Is there a difference in hypertension screening and care in urban population vs rural company in the Democratic Republic of Congo (DRC)?
; ; et al
in Hypertension (2008), 26Detailed reference viewed: 17 (5 ULg)
Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006.
; ; et al
in AIDS Research and Human Retroviruses (2008), 24(3), 355-62
This study is the first prospective study to assess the prevalence, epidemiology, and risk factors of HIV-1 drug resistance in newly diagnosed HIV-infected patients in Belgium. In January 2003 it was ... [more ▼]
This study is the first prospective study to assess the prevalence, epidemiology, and risk factors of HIV-1 drug resistance in newly diagnosed HIV-infected patients in Belgium. In January 2003 it was initiated as part of the pan-European SPREAD program, and continued thereafter for four inclusion rounds until December 2006. Epidemiological, clinical, and behavioral data were collected using a standardized questionnaire and genotypic resistance testing was done on a sample taken within 6 months of diagnosis. Two hundred and eighty-five patients were included. The overall prevalence of transmitted HIV-1 drug resistance in Belgium was 9.5% (27/285, 95% CI: 6.6-13.4). Being infected in Belgium, which largely coincided with harboring a subtype B virus, was found to be significantly associated with transmission of drug resistance. The relatively high rate of baseline resistance might jeopardize the success of first line treatment as more than 1 out of 10 (30/285, 10.5%) viruses did not score as fully susceptible to one of the recommended first-line regimens, i.e., zidovudine, lamivudine, and efavirenz. Our results support the implementation of genotypic resistance testing as a standard of care in all treatment-naive patients in Belgium. [less ▲]Detailed reference viewed: 42 (4 ULg)
Neural correlates of automatic motor responses: an event-related fMRI study
Garraux, Gaëtan ; Peigneux, Philippe ; D'Ostilio, Kevin
Poster (2008)Detailed reference viewed: 17 (0 ULg)
Implicit/explicit memory dissociation in Alzheimer's disease: the consequence of inappropriate processing?
Willems, Sylvie ; Salmon, Eric ; Van der Linden, Martial
in Neuropsychology (2008), 22(6), 710-7
Dual-process theories of recognition posit that perceptual fluency contributes to both familiarity-based explicit recognition and perceptual priming. However, the priming-without-recognition dissociation ... [more ▼]
Dual-process theories of recognition posit that perceptual fluency contributes to both familiarity-based explicit recognition and perceptual priming. However, the priming-without-recognition dissociation, as observed through the intact mere exposure effect and impaired recognition in patients with Alzheimer's disease (AD), might indicate that familiarity and perceptual priming are functionally distinct. This study investigated whether the AD patients' processing strategies at testing may explain this priming-without-recognition dissociation. First, we replicated the priming-without-recognition effect in 16 patients who exhibited intact exposure effects despite null recognition. Second, we showed that, under identical conditions, inducing a holistic processing strategy during recognition testing increased AD patients' recognition--performance was similar for AD patients and healthy control participants. Furthermore, prompting analytic processing during both priming and recognition tasks decreased AD patients' performance in both tasks. These findings suggest that the extent to which AD patients use perceptual fluency in priming and recognition tasks is contingent on their processing approach. The choice of processing strategy may depend on how difficult patients perceive the task to be. [less ▲]Detailed reference viewed: 115 (33 ULg)
Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative
Rousseau, Anne ; Chiap, Patrice ; et al
in Journal of Chromatography. A (2008), 1204(2), 219-225
Nonaqueous capillary electrophoresis (NACE) was successfully applied to the enantiomeric purity determination of R-flurbiprofen using 6-monodeoxy-6-mono(2-hydroxy)propylamino-beta-cyclodextrin (IPA-beta ... [more ▼]
Nonaqueous capillary electrophoresis (NACE) was successfully applied to the enantiomeric purity determination of R-flurbiprofen using 6-monodeoxy-6-mono(2-hydroxy)propylamino-beta-cyclodextrin (IPA-beta-CD) as chiral selector. The nonaqueous BGE was made up of 20 mM IPA-beta-CD, 20 mM ammonium camphorsulfortate and 40 mM ammonium acetate in methanol. Flufenamic acid was selected as internal standard. The CE method was carefully optimized in order to prevent the adsorption of the cationic CD onto the capillary wall, and therefore, to avoid loss of peak efficiency and enantioresolution. To achieve this goal, the addition of ammonium camphorsulfonate was found to be necessary. In the selected conditions, the determination of 0.1% of S-flurbiprofen in R-flurbiprofen could be performed using the method of standard additions. The NACE method was then fully validated by applying a novel strategy using accuracy profiles. (c) 2008 Elsevier B.V. All rights reserved. [less ▲]Detailed reference viewed: 43 (1 ULg)
Aphid-ant mutualism: How do aphids focus ant foraging?
Verheggen, François ; ; et al
Conference (2008)Detailed reference viewed: 12 (5 ULg)
Éco-éthologie d’une population de vipères péliades (Vipera b. berus L.) dans une région de bocage du sud-ouest de la Belgique
in Bulletin de la Société Herpétologique de France (2008), 128
the preference of adders for different linear elements of the ‘bocage’, a farmland landscape crisscrossed by hedges, was studied during 2.5 years in south-West Belgium. Most individuals occurred in South ... [more ▼]
the preference of adders for different linear elements of the ‘bocage’, a farmland landscape crisscrossed by hedges, was studied during 2.5 years in south-West Belgium. Most individuals occurred in South-facing woody hedges between the autumn and the beginning of spring. During the mating period, by contrast, most individuals tended to shift of habitat and favoured 1 to 2 m wide grassy hedges with a limited shrub cover and a north-south orientation. Mating females especially favoured this latter habitat, probably because of their specific micro-climatic conditions, including a higher insulation. A few individuals, however, remained in the same habitat all year round. The identification of individuals, which was performed on the basis of features including body and head color patterns, but not on individual clipping, proved to be difficult owing to the high density of individuals. Linear elements in the form of grassy hedges, not very space-consuming, can shelter very high densities of snakes. in the context of a sharp decrease of the bocage landscape, the conservation of common European vipers relies on the maintenance of such linear landscape elements as grassy and shrubby hedges, which can be enhanced by the implementation of recent measures aiming at restoring extensive agricultural systems. [less ▲]Detailed reference viewed: 175 (7 ULg)
Lesions cerebrales demyelinisantes decouvertes chez un patient immunocompetent VIH-1+.
; Moutschen, Michel ; Demonty, Jean
in Médecine et Maladies Infectieuses (2008), 38(9), 500-3
We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple ... [more ▼]
We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple sclerosis. Histology revealed inflammation with necrosis, demyelination and destruction of axons. Serum tests were negative for various infectious agents as well as specific cultures and PCR. Corticotherapy and many antibiotic treatments failed. Resorption of the lesions occurred after partial excision and highly-active antiretroviral therapy (HAART). No recurrence was noted. This demyelinating cerebral disease was considered as the primary manifestation of HIV infection. HIV implication in the genesis of the process and its perpetuating this condition was suspected, but the mechanism is unclear. Dysimmune consequences related to the early course of HIV infection could be prevented by antiretroviral treatment. This study was the first description of tritherapy effectiveness on HIV related multiple sclerosis (MS)-like illness. [less ▲]Detailed reference viewed: 37 (2 ULg)
Domaine public, domaine privé, biens des pouvoirs publics
Book published by Larcier (2008)Detailed reference viewed: 239 (22 ULg)
Les formules basées sur la créatinine :indiscutable ?
Conference given outside the academic context (2008)Detailed reference viewed: 21 (2 ULg)
Les tumeurs de la sphere ORL: standards de traitement et nouvelles approches en radiotherapie.
Coucke, Philippe ; Piret, Pascal ; Werenne, Xavier et al
in Revue Médicale de Liège (2008), 63(3), 141-8
We intend to review the general value of radiotherapy in the management of head and neck cancer. Our aim is to define a treatment protocol which is evidence-based and therefore of use in daily clinical ... [more ▼]
We intend to review the general value of radiotherapy in the management of head and neck cancer. Our aim is to define a treatment protocol which is evidence-based and therefore of use in daily clinical practice. There is general agreement on the efficacy of the concomitant schedules combining radiotherapy and chemotherapy, both in the adjuvant setting as well as in the exclusive non-surgical approach. This however does not preclude further research aiming at optimizing the therapeutic index. As far as neoadjuvant chemotherapy is concerned, applied prior to radical local treatment, there are no conclusive data available which allows us to implement this treatment option in routine clinical practice. This approach deserves further investigations and patients should be entered in well designed prospective randomized trials. [less ▲]Detailed reference viewed: 163 (16 ULg)
New pyridinic analogues of nimesulide as potent COXs inhibitors.
Renard, Jean-François ; Garbacki, Nancy ; et al
Poster (2008)Detailed reference viewed: 10 (1 ULg)
New Trends in Computing Anticipatory Systems : Emergence of Artificial Conscious Intelligence with Machine Learning Natural Language
in Dubois, Daniel (Ed.) COMPUTING ANTICIPATORY SYSTEMS (2008)
This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the ... [more ▼]
This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the definitions of strong and weak anticipation. The quasi-anticipatory systems of Robert Rosen are linked to open-loop controllers. Then, some properties of the natural brain are presented in relation to the triune brain theory of Paul D. MacLean, and the mind time of Benjamin Libet, with his veto of the free will. The theory of the hyperincursive discrete anticipatory systems is recalled in view to introduce the concept of hyperincursive free will, which gives a similar veto mechanism: free will as unpredictable hyperincursive anticipation The concepts of endo-anticipation and exo-anticipation are then defined. Finally, some ideas about artificial conscious intelligence with natural language are presented, in relation to the Turing Machine, Formal Language, Intelligent Agents and Mutli-Agent System. [less ▲]Detailed reference viewed: 813 (18 ULg)
Shear strength of unsaturated soil and its influence on slope stability
; ; et al
in 1st European Conference on Unsaturated Soils (2008)Detailed reference viewed: 95 (0 ULg)
Authentication in stealth distributed hash tables
; ; et al
in Journal of Systems Architecture (2008), 54(6), 607--618Detailed reference viewed: 6 (0 ULg)