References of "2008"
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See detailAge and the time lag method
Delhez, Eric ULg; Deleersnijder, Eric

in Continental Shelf Research (2008), 28(8), 1057-1067

The time lag method is one of the most straightforward methods used to estimate transit times from experimental data and is therefore widely used. The transit time between two points is estimated from the ... [more ▼]

The time lag method is one of the most straightforward methods used to estimate transit times from experimental data and is therefore widely used. The transit time between two points is estimated from the analysis of time series taken at these two points that suggest the propagation of a signal from one point to the other. To account for the distortion of the signal during its propagation between the two points an optimum time lag can be estimated by the analysis of the cross-correlation of the two time series. This study clarifies the relation between the transit time estimated by the time lag method and the well-defined concept of the age of a water mass. It is shown, through simplified process models, that the time lag method systematically underestimates the true mean age. The error can be quantified by means of a dimensionless parameter which is the inverse of a Peclet number based on a characteristic length given by the ratio of the velocity of the flow to the frequency of the signal. (c) 2008 Elsevier Ltd. All rights reserved. [less ▲]

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See detailPermian
Mc Cann, T.; Kiersnowski, H.; Krainer, K. et al

in Mc Cann, Tom (Ed.) The geology of Central Europe: Precambrian and Palaeozoic (2008)

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See detailCyclosporine, a P-glycoprotein modulator, increases [18F]MPPF uptake in rat brain and peripheral tissues: microPET and ex vivo studies.
Lacan, Goran; Plenevaux, Alain ULg; Rubins, Daniel J. et al

in European Journal of Nuclear Medicine and Molecular Imaging (2008), 35(12), 2256-66

PURPOSE: Pretreatment with cyclosporine, a P-glycoprotein (P-gp) modulator increases brain uptake of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethylpiperaz ine ([(18)F]MPPF) for ... [more ▼]

PURPOSE: Pretreatment with cyclosporine, a P-glycoprotein (P-gp) modulator increases brain uptake of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethylpiperaz ine ([(18)F]MPPF) for binding to hydroxytryptamine(1A) (5-HT(1A)) receptors. Those increases were quantified in rat brain with in vivo microPET and ex vivo tissue studies. MATERIALS AND METHODS: Each Sprague-Dawley rat (n = 4) received a baseline [(18)F]MPPF microPET scan followed by second scan 2-3 weeks later that included cyclosporine pretreatment (50 mg/kg, i.p.). Maximum a posteriori reconstructed images and volumetric ROIs were used to generate dynamic radioactivity concentration measurements for hippocampus, striatum, and cerebellum, with simplified reference tissue method (SRTM) analysis. Western blots were used to semiquantify P-gp regional distribution in brain. RESULTS: MicroPET studies showed that hippocampus uptake of [(18)F]MPPF was increased after cyclosporine; ex vivo studies showed similar increases in hippocampus and frontal cortex at 30 min, and for heart and kidney at 2.5 and 5 min, without concomitant increases in [(18)F]MPPF plasma concentration. P-gp content in cerebellum was twofold higher than in hippocampus or frontal cortex. CONCLUSIONS: These studies confirm and extend prior ex vivo results (J. Passchier, et al., Eur J Pharmacol, 2000) that showed [(18)F]MPPF as a substrate for P-gp. Our microPET results showed that P-gp modulation of [(18)F]MPPF binding to 5-HT(1A) receptors can be imaged in rat hippocampus. The heterogeneous brain distribution of P-gp appeared to invalidate the use of cerebellum as a nonspecific reference region for SRTM modeling. Regional quantitation of P-gp may be necessary for accurate PET assessment of 5-HT(1A) receptor density when based on tracer uptake sensitive to P-gp modulation. [less ▲]

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See detailOn the complementarity of contrastive linguistics and interlanguage studies
Rasier, Laurent ULg; Hiligsmann, Philippe

Conference (2008)

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See detailBoth the hippocampus and striatum are involved in consolidation of motor sequence memory.
Albouy, Geneviève ULg; Sterpenich, Virginie ULg; Balteau, Evelyne ULg et al

in Neuron (2008), 58(2), 261-72

Functional magnetic resonance imaging (fMRI) was used to investigate the cerebral correlates of motor sequence memory consolidation. Participants were scanned while training on an implicit oculomotor ... [more ▼]

Functional magnetic resonance imaging (fMRI) was used to investigate the cerebral correlates of motor sequence memory consolidation. Participants were scanned while training on an implicit oculomotor sequence learning task and during a single testing session taking place 30 min, 5 hr, or 24 hr later. During training, responses observed in hippocampus and striatum were linearly related to the gain in performance observed overnight, but not over the day. Responses in both structures were significantly larger at 24 hr than at 30 min or 5 hr. Additionally, the competitive interaction observed between these structures during training became cooperative overnight. These results stress the importance of both hippocampus and striatum in procedural memory consolidation. Responses in these areas during training seem to condition the overnight memory processing that is associated with a change in their functional interactions. These results show that both structures interact during motor sequence consolidation to optimize subsequent behavior. [less ▲]

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See detailModélisation numérique et gestion du risque inondation en milieu urbain sur base de modèles topographiques à haute résolution
Detrembleur, Sylvain ULg; Dewals, Benjamin ULg; Archambeau, Pierre ULg et al

in 3e journées doctorales en hydrologie urbaine (2008)

Dans le cadre général des grands événements récurrents d'inondation enregistrés à travers le monde et en Europe en particulier, des cartes d'inondation représenteraient un outil de grand intérêt pour les ... [more ▼]

Dans le cadre général des grands événements récurrents d'inondation enregistrés à travers le monde et en Europe en particulier, des cartes d'inondation représenteraient un outil de grand intérêt pour les décideurs en matière d’aménagement du territoire mais aussi pour les compagnies d'assurance afin d’évaluer les risques liés à l'inondation ou encore pour permettre une gestion de crise efficace sur le terrain. Dans ce but, des cartes complètes et précises sont nécessaires pour différents événements de probabilités données. En Belgique, début 2003, suivant une décision du gouvernement wallon, le modèle d’écoulements à surface libre WOLF2D a été officiellement choisi pour calculer des cartes d'inondation sur 800 kilomètres de cours d’eau en région wallonne en utilisant un modèle numérique de terrain à très haute résolution. Les résultats de ces calculs ont, par la suite, été utilisés par l'administration wallonne afin de concevoir la carte d’aléa inondation sur l’ensemble du territoire. Le modèle hydraulique employé est intégré dans la suite logicielle WOLF, qui est développée depuis plus de dix ans à l'Université de Liège. Basée sur la formulation classique des équations en eaux peu profondes, sa discrétisation en volumes finis permet de traiter tout écoulement composé de mailles sèches et mouillées tout en assurant exactement la conservation du volume. Le caractère multiblocs du logiciel permet de modéliser des raffinements locaux du maillage au niveau des centres urbains tout en conservant, si nécessaire, des maillages plus lâches dans les grandes plaines inondables. Par ailleurs, des procédés de raffinement automatique du maillage permettent d’accélérer fortement les temps de calcul. Un modèle moyenné de turbulence type k-ε peut également être employé et renforce ainsi les potentialités du modèle face aux écoulements complexes. Une interface permet en outre de gérer l’ensemble des procédures de pré et post processing nécessaires à la conception des modélisations et à l’interprétation des résultats. Les opérations d'importation et d'exportation sont facilement réalisables vers la plupart des outils SIG classiques. Différentes couches de cartes peuvent être manipulées pour analyser les informations relatives à la topographie, à l’occupation du sol, à la densité de la végétation ou encore aux champs hydrodynamiques. Grâce à l'utilisation de modèles topographiques de haute résolution (1 point par mètre carré) disponible sur le lit principal comme sur les plaines d'inondation des cours d’eau étudiés, des modélisations basées sur des maillages composés de cellules carrées de 2m x 2m ont été réalisées notamment au droit des centres urbains traversés par les rivières. Le modèle hydraulique a été intensivement validé par des comparaisons avec des observations lors d’événements récents. L'incertitude globale du modèle s'est avérée inférieure à 10 centimètres en termes de surface libre et permet de décrire l’inondation rue par rue et maison par maison. [less ▲]

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See detailAn experimental analysis of effects induced by moving bodies in shallow water
Kerger, François ULg; Detrembleur, Sylvain ULg; Archambeau, Pierre ULg et al

in Proc. 2nd International Junior Researcher and Engineer Workshop on Hydraulic Structures (2008)

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See detailLa copropriété par appartements
Lecocq, Pascale ULg

Book published by La Charte (2008)

L'ouvrage analyse les thèmes principaux de la copropriété par appartements (Champ d'application, association des copropriétaires, organes, contentieux, transmission d'un lot, comptabilité, conciliation et ... [more ▼]

L'ouvrage analyse les thèmes principaux de la copropriété par appartements (Champ d'application, association des copropriétaires, organes, contentieux, transmission d'un lot, comptabilité, conciliation et médiation, ...) au regard de la pratique issue de la loi du 30 juin 1994 et de la nouvelle proposition de loi en la matière. [less ▲]

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See detailIon-beam analysis for cultural heritage on the AGLAE facility: impact of PIXE/RBS combination
Salomon, Joseph; Dran, Jean-Claude; Guillou, T. et al

in Applied Physics A : Materials Science & Processing (2008), 92(1), 43-50

The combination of particle-induced X-ray emission (PIXE) and Rutherford backscattering (RBS) is particularly fruitful for the study of cultural heritage objects. Several set-ups have been developed at ... [more ▼]

The combination of particle-induced X-ray emission (PIXE) and Rutherford backscattering (RBS) is particularly fruitful for the study of cultural heritage objects. Several set-ups have been developed at the AGLAE facility of the Louvre Laboratory to implement these techniques with an external beam. Successively have been tested the simultaneous use of PIXE and RBS with a single beam of protons, the sequential application of PIXE with protons and RBS with 4He2+ ions and finally the simultaneous implementation of PIXE and RBS with high-energy 4He2+ ions. Several examples illustrate the benefits of these combinations of techniques. [less ▲]

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See detailDirected forgetting and aging: the role of retrieval processes, processing speed, and proactive interference.
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

in Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition (2008), 15(4), 471-91

The directed forgetting effect obtained with the item method is supposed to depend on both selective rehearsal of to-be-remembered (TBR) items and attentional inhibition of to-be-forgotten (TBF) items. In ... [more ▼]

The directed forgetting effect obtained with the item method is supposed to depend on both selective rehearsal of to-be-remembered (TBR) items and attentional inhibition of to-be-forgotten (TBF) items. In this study, we investigated the locus of the directed forgetting deficit in older adults by exploring the influence of recollection and familiarity-based retrieval processes on age-related differences in directed forgetting. Moreover, we explored the influence of processing speed, short-term memory capacity, thought suppression tendencies, and sensitivity to proactive interference on performance. The results indicated that older adults' directed forgetting difficulties are due to decreased recollection of TBR items, associated with increased automatic retrieval of TBF items. Moreover, processing speed and proactive interference appeared to be responsible for the decreased recall of TBR items. [less ▲]

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See detailExtraction, caractérisation et activités antimicrobiennes de quelques huiles essentielles des plantes du haut et moyen atlas du Maroc
Dahak, K.; Lakhmili, S.; Wathelet, Jean-Paul ULg et al

Conference (2008)

Notre étude a porté sur l'extraction des huiles essentielles (HE) de certaines plantes Marocaines du haut Atlas: région de Marrakech (Citrus aurantium, Lavandula dentata et Feoniculum vulgare) et du moyen ... [more ▼]

Notre étude a porté sur l'extraction des huiles essentielles (HE) de certaines plantes Marocaines du haut Atlas: région de Marrakech (Citrus aurantium, Lavandula dentata et Feoniculum vulgare) et du moyen Atlas: région d’azilal (Ouaouizerth) (Laurus nobilis et Lavandula officinalis). [less ▲]

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See detailConcentrations of organobrominated compounds of natural and industrial origin in top predators from Brazilian waters
Dorneles, Paulo; Lailson-Brito, José; Covaci, Adrian et al

in Organohalogen Compounds (2008), 70

The main objective of the present study was to determine the current concentrations of organobrominated compounds in odontocete species from a highly industrialized and urbanized region in the Southern ... [more ▼]

The main objective of the present study was to determine the current concentrations of organobrominated compounds in odontocete species from a highly industrialized and urbanized region in the Southern Hemisphere. [less ▲]

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See detailCommunication as a sign of adaptation to a complex system: The case of robotic surgery
Nyssen, Anne-Sophie ULg; Blavier, Adelaïde ULg

in Nemeth, C. (Ed.) Improving Healthcare Team Communication: Building on Lessons from Aviation and Aerospace (2008)

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See detailImpact of dust processes on air quality in Niamey, Niger, and consequences on human health
Ozer, Pierre ULg

in Gabriels, Donald; Cornelis, Wim M.; Eyletters, Murielle (Eds.) et al Combating desertification: Assessment, adaptation and mitigation strategies (2008)

It is now irrefutable that air pollution caused by large amounts of respiratory particulates (Particulate Matter less than 10 µm in aerodynamic diameter, PM10) has numerous undesired consequences on human ... [more ▼]

It is now irrefutable that air pollution caused by large amounts of respiratory particulates (Particulate Matter less than 10 µm in aerodynamic diameter, PM10) has numerous undesired consequences on human health. Although air quality degradation far away from the African continent in the US and in Europe caused by high concentration of African dust is seen as a major health threat although most of these countries are very distant from the Sahara; no estimates of PM10 levels near the Saharan dust source are available. Based on horizontal visibility observations which are reduced by the presence of dust in the atmosphere, PM10 levels are estimated during 2005 at Niamey-Airport, Niger. It appears that excessive concentrations of particles are very important both in magnitude and frequency as the 24-hour PM10 thresholds established by the US EPA National Ambient Air Quality Standards and the EU Limits Values for Air Quality were exceeded 103 and 67 times, respectively. The average yearly concentration is far above air quality standards and estimated to 92 µg m-3 for PM10. These very high particulate levels are likely to represent an important public health threat and should be considered as a major environmental risk. [less ▲]

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See detailAccuracy of prediction of gene content in large animal populations and its use for candidate gene detection and genetic evaluation
Gengler, Nicolas ULg; Abras, S.; Verkenne, C. et al

in Journal of Dairy Science (2008), 91(4), 1652-1659

To estimate and to use the effects of single genes on quantitative traits, genotypes need to be known. However, in large animal populations, the majority of animals are not genotyped. These missing ... [more ▼]

To estimate and to use the effects of single genes on quantitative traits, genotypes need to be known. However, in large animal populations, the majority of animals are not genotyped. These missing genotypes have to be estimated. However, currently used methods are impractical for large pedigrees. An alternative method to estimate missing gene content, defined as the number of copies of a particular allele, was recently developed. In this study, the proposed method was tested by assessing its accuracy in estimation and use of gene content in large animal populations. This was done for the bovine transmembrane growth hormone receptor and its effects on first-lactation milk, fat, and protein test-day yields and somatic cell score in Holstein cows. Estimated gene substitution effects of replacing a copy of the phenylalanine-coding allele with a copy of the tyrosine-coding allele were 295 g/d for milk, -8.14 g/d for fat, -1.83 g/d for protein, and -0.022/d for somatic cell score. However, only the gene substitution effect for milk was found to be significant. The accuracy of the estimated effects was evaluated by simulations and permutations. To validate the use of predicted gene content in a mixed inheritance model, a cross-validation study was done. The model with an additional regression of milk, fat, and protein yields and SCS on predicted gene content showed a better capacity to predict breeding values for milk, fat, and protein. Given these results, the estimation and use of allelic effects using this method proved functional and accurate. [less ▲]

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See detailAccessibilité, Aire d’influence d’une ville (aire de chalandise), Centre commerçant, Facteurs de localisation du commerce, Friche commerciale, Géographie du commerce de détail, Immobilier commercial, Indices de standing, de modernisme et de spécialisation d’une entité commerciale, Isochrones
Merenne-Schoumaker, Bernadette ULg

in Desse, René-Paul (Ed.) Dictionnaire du commerce et de l’aménagement (2008)

Neuf rubriques dans un dictionnaire cherchant à croiser la géographie du commerce de détail et l'aménagement

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See detailStem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease.
Bantubungi, Kadiombo; Blum, David; Cuvelier, Laetitia et al

in Molecular & Cellular Neuroscience [=MCN] (2008), 37(3), 454-70

Neural and mesenchymal stem cells have been proposed as alternative sources of cells for transplantation into the brain in neurodegenerative disorders. However, the endogenous factors controlling their ... [more ▼]

Neural and mesenchymal stem cells have been proposed as alternative sources of cells for transplantation into the brain in neurodegenerative disorders. However, the endogenous factors controlling their engraftment within the injured parenchyma remain ill-defined. Here, we demonstrate significant engraftment of undifferentiated exogenous mesenchymal or neural stem cells throughout the lesioned area in a rat model for Huntington's disease, as late as 8 weeks post-transplantation. We show that stem cell factor (SCF), strongly up-regulated within host cells in the damaged striatum, is able to activate the SCF receptor c-kit and its signaling pathway and to promote the migration and proliferation of mesenchymal and neural stem cells in vitro. Furthermore, c-kit receptor blockade alters neural stem cell distribution within the lesioned striatum. Host SCF expression is observed in atypical cells expressing glial fibrillary acidic protein and doublecortin in the lesioned striatum and in migrating doublecortin-positive progenitors. Taken together, these data demonstrate that SCF produced in situ in the lesioned striatum is an important factor in promoting the engraftment of stem cells within the lesioned brain. [less ▲]

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