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See detailL'étude clinique du mois. JUPITER : diminution par la rosuvastatine des accidents cardio-vasculaires et de la mortalité chez des sujets sains normolipémiques avec C-réactive protéine accrue
Scheen, André ULiege

in Revue Médicale de Liège (2008), 63(12), 749-753

SUMMARY : High levels of high-sensitivity C-reactive protein (hs-CRP) are an independent cardiovascular marker, which may be reduced by statin therapy. JUPITER is a randomised clinical trial that compares ... [more ▼]

SUMMARY : High levels of high-sensitivity C-reactive protein (hs-CRP) are an independent cardiovascular marker, which may be reduced by statin therapy. JUPITER is a randomised clinical trial that compares the effects of rosuvastatin 20 mg (n = 8901) and placebo (n = 8901) in apparently healthy individuals, <br />without hyperlipidaemia (LDL < 130 mg/dl ; median 108 mg/dl), but with moderately elevated hs-CRP levels (> 2 mg/l ; median 4.25 mg/l). Rosuvastatin reduced LDL cholesterol by 50 % (to a median of 55 mg/dl) and hs-CRP by 37 %. The trial, which should last 5 years, was stopped after a median follow-up of 1.9 years because of an imbalance in favour of the rosuvastatin group. Indeed, when compared to placebo, rosuvastatin <br />was associated with a relative risk reduction in the composite primary end point of 44 %, in myocardial infarction of 54 %, in stroke of 48 %, in revascularization procedures or hospitalisations for unstable angina of 47 %, in major cardiovascular <br />events (myocardial infarction, stroke and death) of 47 % and in deaths from any cause of 20 %. Consistent effects were observed in all subgroups evaluated. The only adverse event was a higher incidence of physician-reported diabetes in the rosuvastatin group compared to the placebo group. This study demonstrates that rosuvastatin 20 mg reduces the incidence <br />of cardiovascular events, including total mortality, in apparently healthy persons without hyperlipidaemia, but with elevated hs-CRP. However, the design of the trial does not allow discriminating which part of the favourable effect results from the drastic reduction in LDL cholesterol and which part results from the reduction in hs-CRP stricto sensu. [less ▲]

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See detailPerturbation Finite Element Method for Refining Magnetic Circuit Models
Dular, Patrick ULiege; V Sabariego, Ruth ULiege; Ferreira da Luz, Mauricio Valencia et al

in Proceedings of the XX Symposium Electromagnetic Phenomena in Nonlinear Circuits (EPNC2008) (2008)

Model refinements of magnetic circuits are performed via a subproblem finite element method based on a perturbation technique. An approximate problem considering ideal flux tubes is first solved. It gives ... [more ▼]

Model refinements of magnetic circuits are performed via a subproblem finite element method based on a perturbation technique. An approximate problem considering ideal flux tubes is first solved. It gives the sources for finite element perturbation problems considering all the details of the exterior regions, thus accounting for leakage fluxes. The procedure simplifies both meshing and solving processes. It quantifies the gain given by each model refinement on both local and global quantities. [less ▲]

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See detailConcentration of bovine pregnancy associated glycoprotein in plasma and milk: its application for pregnancy diagnosis in cows
Gajewski, Z.; Melo de Sousa, Noelita ULiege; Beckers, Jean-François ULiege et al

in Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society (2008), 59(Suppl 9), 55-64

Pregnancy diagnosis is an important part in reproduction management of ruminants. The aim of the study was to use a new method for evaluating the bPAG and cPAG in milk and blood bPAG and compare this ... [more ▼]

Pregnancy diagnosis is an important part in reproduction management of ruminants. The aim of the study was to use a new method for evaluating the bPAG and cPAG in milk and blood bPAG and compare this results with the other method for pregnancy diagnosis in the cows. The study was carried out in 220 Holstein Frisian cows. Heparinised blood samples were taken from the jugular vein and stored at -20 degrees C until PAG assay by RIA. For bPAG and cPAG, RIA test, milk samples were homogenized. Pure bPAG was used as a standard tracer described by Zoli et al. (1992). The cows were diagnosed as pregnant by means of USG (Aloka SSD 210) and by rectal palpation. bPAG and cPAG concentration in milk increased after 28 day of pregnancy and showed the rapid increase near the parturition. The same results of bPAG concentration we obtained in the blood samples. The decline of bPAG concentration was faster in the milk than in the blood. The data showed that the RIA method is precise enough to measure PAG concentrations in the maternal blood and milk of cows. The data indicate that milk samples can be used for pregnancy diagnosis in cows. The sensitivity and specificity of RIA measurement of PAG are very high. [less ▲]

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See detailRéussite à l'insémination en élevages ovins laitiers pyrénéens : facteurs de variantion liés aux conduites de troupeaux
Arranz, J. M.; Freret, S.; Fidelle, F. et al

in Proceedings de la 15e Journée sur les Rencontres de Recherche chez les Ruminants (2008)

En élevage ovin-lait, la réussite à l’insémination artificielle (IA) est un facteur clé pour la maîtrise de la reproduction et la mise en œuvre des schémas de sélection. Elle a été évaluée : 1) par dosage ... [more ▼]

En élevage ovin-lait, la réussite à l’insémination artificielle (IA) est un facteur clé pour la maîtrise de la reproduction et la mise en œuvre des schémas de sélection. Elle a été évaluée : 1) par dosage de la PAG plasmatique vingt huit jours après l’insémination ; 2) par l’analyse des résultats de mise bas (MB). La différence entre ces deux valeurs permet d’estimer le niveau de pertes embryonnaires et avortements. L’étude porte sur quatre-vingt cinq lots d’insémination (8841 brebis de races Manech / Latxa tête rousse et tête noire principalement) réalisés de mai à août 2007, dans trois centres d’insémination (CIA) transfrontaliers : Navarre, communauté autonome d’Euskadi et Pyrénées Atlantiques. Les données de contrôle laitier et des CIA ont été mobilisées pour étudier les facteurs de variation de la fertilité individuelle. Un deuxième volet de l’étude, à l’échelle des lots, traite des conduites d’élevage pendant la période de lutte. Il s’appuie sur des enquêtes (alimentation, chantiers d’IA, sanitaire). La fertilité à vingt huit jours s’élève à 61,3 % et celle à la MB à 55,2 %. Les pertes sont en moyenne de 6,2 %. Pour 2/3 des lots elles sont inférieures à 7 %. L’analyse des facteurs individuels, tant pour la fertilité à vingt huit jours qu’à la MB, confirme les effets classiques des facteurs de variation de la fertilité à l’IA : intervalle IA-MB précédente, âge des femelles, mode de reproduction de la campagne précédente, production laitière au moment de l’IA, qualité de la semence. Les niveaux de pertes sont plus élevés pour les jeunes ou lorsque l’intervalle est court. Au niveau des conduites d’élevage, on observe une interaction forte race*région associée à des périodes d’IA et des conduites alimentaires différentes, mais avec des effets peu ou pas significatifs de ces conduites. Les enquêtes sanitaires font apparaître des niveaux de risques et des pathologies comparables d’une région à l’autre et élevés. Pour les lots à pertes élevées, celles-ci ont pu être reliées à des problèmes pathologiques particuliers, mais non prévisibles. Une telle approche, assez complète et globale des conduites, aura permis de renouveler le conseil en élevage et d’élargir les capacités d’intervention des techniciens. [less ▲]

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See detailProperties of Random Quantum States: Monte Carlo sampling versus analytical approximations.
Fresch, Barbara ULiege; Moro, Giorgio J.

Poster (2008)

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See detailCompte rendu de Faire l'évènement au Moyen Âge, éd. C. CAROZZI, H. TAVIANI-CAROZZI
Masson, Christophe ULiege

in Moyen Age (Le) (2008), CXIV

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See detailDéveloppement durable: évalutions des projets
Fauconnier, Marie-Laure ULiege

Report (2008)

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See detailIdentification des localisations optimales des activités économiques locales
Bastin, A.; Chevau, T.; Hiligsman, S. et al

Report (2008)

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See detailL'historien, acteur de mémoire?
Raxhon, Philippe ULiege

in Deproost, Paul-Augustin; van Ypersele, Laurence; Watthée-Delmotte, Myriam (Eds.) Mémoire et identité. Parcours dans l'imaginaire occidental (2008)

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See detailStress constrained topology and shape optimization : Specific character and large scale optimization algorithms
Duysinx, Pierre ULiege; Fleury, Claude; Van Miegroet, Laurent ULiege et al

in Proceedings of the 8th World Congress on Computational Mechanics (WCCM) (2008)

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See detailStimulus-response curve of human motor nerves: multicenter assessment of various indexes.
Boerio, D.; Hogrel, J.-Y.; Lefaucheur, J.-P. et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2008), 38(1), 31-8

The value of various indexes to characterize the stimulus-response curve of human motor nerves was assessed in 40 healthy subjects recruited from four European centers of investigation (Creteil, Lausanne ... [more ▼]

The value of various indexes to characterize the stimulus-response curve of human motor nerves was assessed in 40 healthy subjects recruited from four European centers of investigation (Creteil, Lausanne, Liege, Marseille). Stimulus-response curves were established by stimulating the right median and ulnar motor nerves at the wrist, with stimulus durations of 0.05 and 0.5 ms. The following parameters were studied: the threshold intensity of stimulation to obtain 10% (I 10), 50% (I 50), and 90% (I 90) of the maximal compound muscle action potential, the ratios I 10/I 50, I 90/I 50, (I 90 - I 10)/I 10, (I 90-I 50)/I 50, and (I 50 - I 10)/I 10, and the slopes of the stimulus-response curves with or without normalization to I 50. For each parameter, within-center variability and reproducibility (in a test-retest study) were assessed and between-center comparisons were made. For most of the parameters, the results varied significantly within and between the centers. Within the centers, only the ratios I 10/I 50 and I 90/I 50 were found constant and reproducible. Between the centers, the absolute intensity thresholds (I 10, I 50, I 90) and the ratio I 90/I 50 did not show significant differences at stimulus duration of 0.5 ms, whatever the stimulated nerve. The reduced variability and good reproducibility of the ratios I 10/I 50 and I 90/I 50 open perspectives in neurophysiological practice for the use of these indexes of the stimulus-response curve, a rapid and noninvasive test. [less ▲]

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See detailCartographie d'économie sociale
Breuer, Christophe ULiege; Jaspard, Mathieu ULiege; Devillet, Guénaël ULiege et al

Cartographic material (2008)

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See detailIncola est. About European Citizenship
Carlier, Jean-Yves ULiege

in Böcker, Anita; Havinga, Terry; van de Put, Annie (Eds.) et al Migratierecht en rechtssociologie, gebundeld in Kees' studies, Migration Law and Sociology of Law, collected essays in honour of Kees Groenendijk (2008)

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See detailBiomarkers of heart disease
Amory, Hélène ULiege; Deleuze, Stefan ULiege; Sandersen, Charlotte ULiege

in Proceedings of the Second Resident Meeting of the European College of Equine Internal medicine (ECEIM) (2008)

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See detailDCDS - Distant Collaborative Design Studio. An Initial Experimentation in Distant Collaborative Design Studio in Architecture.
Elsen, Catherine ULiege; Juchmes, Roland ULiege; Kubicki, Sylvain et al

in Muylle, Marc (Ed.) Architecture "in computero", Integrating Methods and Techniques. Proceedings of the 26th eCAADe Conference on Education and Research in Computer Aided Architectural Design in Europe. (2008)

This paper introduces new supporting tools in the field of distant collaborative design, namely DCDS and CRTI-weB. These prototypes respectively support: the early stages of design, through the support of ... [more ▼]

This paper introduces new supporting tools in the field of distant collaborative design, namely DCDS and CRTI-weB. These prototypes respectively support: the early stages of design, through the support of the crucial initial step of free-hand sketches shared in real-time, and the asynchronous collaborative activities. The main goal of this paper is to propose the use of these innovative tools as an efficient and realistic way of managing long distance collaboration, to effectively serve the designers’ needs. This proposition is analyzed and questioned through a real-size experiment featuring 30 architecture and architectural-engineering students, working together in real-time in different locations (Belgium and France). This experiment and the necessary survey open up interesting fields of investigation, such as the relevance of the proposed devices in supporting distant collaborative design in architecture and the benefit this represents for students to merge the IT aspects and the design studio. The methodology and the replicability are analyzed to increase the level and quality of formation of our students and, finally, a critique of the tools confirms a benefit for the developing teams. [less ▲]

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