References of "2008"
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See detailWood remains and sporomorphs from the Wealden facies of Hautrage (Mons Basin, Belgium): palaeoclimatic and palaeoenvironnemental implications.
Gerards, Thomas ULiege; Yans, Johan; Spagna, Paul et al

in Memoirs of the Geological Survey of Belgium (2008), 55

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See detailThe global biogeography of semi-arid periodic vegetation patterns.
Deblauwe, V; Barbier, N; Couteron, P et al

in Global Ecology & Biogeography (2008), 17(6), 715-723

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See detailInnate sound production in the cichlid Oreochromis niloticus
Longrie, Nicolas ULiege; Fine, M. L.; Parmentier, Eric ULiege

in Journal of Zoology (2008), 275

The mouthbrooding cichlid Oreochromis niloticus is one of the world’s best-studied fish and is raised extensively for aquaculture. Although it is a common behavioural model, its acoustic communication has ... [more ▼]

The mouthbrooding cichlid Oreochromis niloticus is one of the world’s best-studied fish and is raised extensively for aquaculture. Although it is a common behavioural model, its acoustic communication has been neglected. Because of extensive parental care, the species is a good candidate for vocal learning. In male O. niloticus, we investigated for the first time sound production in agonistic interactions during nest construction. Males produce short-duration (250– 400 ms), often double-pulse sounds. Most energy is below 200 Hz and includes three main low-frequency peaks although energy extends beyond 1 kHz. Males (separated as eggs and raised in isolation) produce similar sounds in the same context as parental fish, indicating that the ability to produce sounds and the basic properties of the sounds are innate. [less ▲]

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See detailA Chemical Platform for the Design of Versatile AFM Probes
Willet, Nicolas ULiege; Duwez, Anne-Sophie ULiege

in Hinterdorfer, Peter; Schütz, Gerhard; Pohl, Peter (Eds.) Proceedings of the IX. Linz Winter Workshop 2007 (2008)

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See detailPregnancy-Associated Glycoprotein I-50 kDa [Fragment] from Bison bonasus placenta - Access number P85327
Kiewisz, J.; Melo de Sousa, Noelita ULiege; Beckers, Jean-François ULiege et al

E-print/Working paper (2008)

N-terminal microsequence obtained after purification and characterization of placental proteins in Bison bonasus. Proteins were submitted to SwissProt databank.

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See detailHigh-resolution clutter-power estimation for range-dependence compensation in conformal-array STAP
Ries, Philippe; Lapierre, Fabian D.; Lesturgie, Marc et al

Conference (2008)

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See detailCrystal chemistry of natural and synthetic fillowite-type phosphates
Hatert, Frédéric ULiege; Keller, Paul; Grew, Ed et al

Conference (2008)

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See detailDifferential diagnosis of equine systolic murmurs
Amory, Hélène ULiege

in In the Proceedings of the Voorjaardagen Congress (2008)

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See detailModelling the Fringing of the FORS2 CCD
Walsh, J. R.; Kuntschner, H.; Jehin, Emmanuel ULiege et al

in Kaufer, A. (Ed.) The 2007 ESO Instrument Calibration Workshop (2008)

Thinned CCD detectors display fringing which arises from the interference of multiply reflected light in the layers of the CCD. If the layer construction - the thicknesses and refractive indexes of the ... [more ▼]

Thinned CCD detectors display fringing which arises from the interference of multiply reflected light in the layers of the CCD. If the layer construction - the thicknesses and refractive indexes of the layers - is known, then the observed fringing can be accurately modelled and used to correct imaging and spectroscopic data for its effects. In practice the specifications on the actual deposited layer thicknesses may not be known to sufficient accuracy to predict the fringe behaviour. Thus calibration data, in the form of monochromatic flat fields, is required and can be modelled using the technique outlined by Malamuth et al. 2003, which has been applied to ACS CCDs. [less ▲]

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See detailFamille, sexualité et pouvoir dans "L’Ogre" de Jacques Chessex et "Le Jardin d’acclimatation" d’Yves Navarre
Sindaco, Sarah ULiege

in Bouliane, Claudia; Popovic, Pierre (Eds.) La Ve République des Goncourt (2008)

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See detailThe Middle to Upper Palaeolithic transition in the North-Western European plain
Flas, Damien ULiege

Scientific conference (2008)

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See detailImpact of geometry and viewing angle on classification accuracy of 2D based analysis of dysmorphic faces
Vollmar, Tobias; Maus, Bärbel ULiege; Wurtz, R. P. et al

in European Journal of Medical Genetics (2008), 51(1), 44-53

Digital image analysis of faces has been demonstrated to be effective in a small number of syndromes. In this paper we investigate several aspects that help bringing these methods closer to clinical ... [more ▼]

Digital image analysis of faces has been demonstrated to be effective in a small number of syndromes. In this paper we investigate several aspects that help bringing these methods closer to clinical application. First, we investigate the impact of increasing the number of syndromes from 10 to 14 as compared to an earlier study. Second, we include a side-view pose into the analysis and third, we scrutinize the effect of geometry information. Picture analysis uses a Gabor wavelet transform, standardization of landmark coordinates and subsequent statistical analysis. We can demonstrate that classification accuracy drops from 76% for 10 syndromes to 70% for 14 syndromes for frontal images. Including side-views achieves an accuracy of 76% again. Geometry performs excellently with 85% for combined poses. Combination of wavelets and geometry for both poses increases accuracy to 93%. In conclusion, a larger number of syndromes can be handled effectively by means of image analysis. [less ▲]

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See detailPotential implication of host/symbiont recognition mechanisms in coral bleaching
Vidal-Dupiol, Jérémie; Mitta, Guillaume; Roger, Emmanuel et al

Poster (2008)

Bleaching in corals can be attributed to loss of endosymbiotic zooxanthellae and/or loss of photosynthetic pigments within zooxanthellae. This major disturbance of the reef ecosystem is principally ... [more ▼]

Bleaching in corals can be attributed to loss of endosymbiotic zooxanthellae and/or loss of photosynthetic pigments within zooxanthellae. This major disturbance of the reef ecosystem is principally induced by increases in water temperature. Since the beginning of the 80ís and the onset of global climate change, this phenomenon has been occurring at increasing rates and scales, and with increasing severity. In this study, we focused on finding early regulated genes involved in bleaching. In aquaria, one set of Pocillopora damicornis nubbins was subjected to a gradual seawater temperature increase from 28°C to 32°C over 15 days, and a second control set remained at constant temperature (28°C). Bleaching was monitored by measuring zooxanthellae density. The mRNA differentially expressed between the stressed state (sampled just before the onset of bleaching) and the non stressed state (control) were isolated from the nubbins by Suppression Subtractive Hybridization. The corresponding cDNA were sequenced and confronted to sequence databases to obtain gene similarities. Finally, transcription rates of the most interesting genes were conducted by Q-PCR. Two particularly interesting candidate genes showed an important decrease in their transcription rates following thermal stress and before zooxanthellae loss. These two genes show similarities with genes involved in host/symbiont and host/parasite models. The implication of these molecular actors suggests a possible role of recognition mechanisms between the host and its symbiont, in the breakdown of the symbiosis during the bleaching phenomenon. Experiments such as RACE-PCR, in situ hybridization and immunohistochemistry are currently underway to confirm our hypotheses. [less ▲]

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See detailLa stabilisation fonctionnelle lombaire : Défintion du concept et arguments scientifiques
Demoulin, Christophe ULiege; DISTREE, Vincent ULiege; TOMASELLA, Marco ULiege et al

in Abstract book des Mardis de la Kinésithérapie (2008)

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See detailEngineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils
Chan, Pak Ho; Pardon, Els; Menzer, Linda ULiege et al

in Biochemistry (2008), 47

single-domain fragment, cAb-HuL22, of a camelid heavy-chain antibody specific for the active site of human lysozyme has been generated, and its effects on the properties of the I56T and D67H amyloidogenic ... [more ▼]

single-domain fragment, cAb-HuL22, of a camelid heavy-chain antibody specific for the active site of human lysozyme has been generated, and its effects on the properties of the I56T and D67H amyloidogenic variants of human lysozyme, which are associated with a form of systemic amyloidosis, have been investigated by a wide range of biophysical techniques. Pulse-labeling hydrogen-deuterium exchange experiments monitored by mass spectrometry reveal that binding of the antibody fragment strongly inhibits the locally cooperative unfolding of the I56T and D67H variants and restores their global cooperativity to that characteristic of the wild-type protein. The antibody fragment was, however, not stable enough under the conditions used to explore its ability to perturb the aggregation behavior of the lysozyme amyloidogenic variants. We therefore engineered a more stable version of cAb-HuL22 by adding a disulfide bridge between the two beta-sheets in the hydrophobic core of the protein. The binding of this engineered antibody fragment to the amyloidogenic variants of lysozyme inhibited their aggregation into fibrils. These findings support the premise that the reduction in global cooperativity caused by the pathogenic mutations in the lysozyme gene is the determining feature underlying their amyloidogenicity. These observations indicate further that molecular targeting of enzyme active sites, and of protein binding sites in general, is an effective strategy for inhibiting or preventing the aberrant self-assembly process that is often a consequence of protein mutation and the origin of pathogenicity. Moreover, this work further demonstrates the unique properties of camelid single-domain antibody fragments as structural probes for studying the mechanism of aggregation and as potential inhibitors of fibril formation. [less ▲]

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See detailL'étude clinique du mois. JUPITER : diminution par la rosuvastatine des accidents cardio-vasculaires et de la mortalité chez des sujets sains normolipémiques avec C-réactive protéine accrue
Scheen, André ULiege

in Revue Médicale de Liège (2008), 63(12), 749-753

SUMMARY : High levels of high-sensitivity C-reactive protein (hs-CRP) are an independent cardiovascular marker, which may be reduced by statin therapy. JUPITER is a randomised clinical trial that compares ... [more ▼]

SUMMARY : High levels of high-sensitivity C-reactive protein (hs-CRP) are an independent cardiovascular marker, which may be reduced by statin therapy. JUPITER is a randomised clinical trial that compares the effects of rosuvastatin 20 mg (n = 8901) and placebo (n = 8901) in apparently healthy individuals, <br />without hyperlipidaemia (LDL < 130 mg/dl ; median 108 mg/dl), but with moderately elevated hs-CRP levels (> 2 mg/l ; median 4.25 mg/l). Rosuvastatin reduced LDL cholesterol by 50 % (to a median of 55 mg/dl) and hs-CRP by 37 %. The trial, which should last 5 years, was stopped after a median follow-up of 1.9 years because of an imbalance in favour of the rosuvastatin group. Indeed, when compared to placebo, rosuvastatin <br />was associated with a relative risk reduction in the composite primary end point of 44 %, in myocardial infarction of 54 %, in stroke of 48 %, in revascularization procedures or hospitalisations for unstable angina of 47 %, in major cardiovascular <br />events (myocardial infarction, stroke and death) of 47 % and in deaths from any cause of 20 %. Consistent effects were observed in all subgroups evaluated. The only adverse event was a higher incidence of physician-reported diabetes in the rosuvastatin group compared to the placebo group. This study demonstrates that rosuvastatin 20 mg reduces the incidence <br />of cardiovascular events, including total mortality, in apparently healthy persons without hyperlipidaemia, but with elevated hs-CRP. However, the design of the trial does not allow discriminating which part of the favourable effect results from the drastic reduction in LDL cholesterol and which part results from the reduction in hs-CRP stricto sensu. [less ▲]

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See detailPerturbation Finite Element Method for Refining Magnetic Circuit Models
Dular, Patrick ULiege; V Sabariego, Ruth ULiege; Ferreira da Luz, Mauricio Valencia et al

in Proceedings of the XX Symposium Electromagnetic Phenomena in Nonlinear Circuits (EPNC2008) (2008)

Model refinements of magnetic circuits are performed via a subproblem finite element method based on a perturbation technique. An approximate problem considering ideal flux tubes is first solved. It gives ... [more ▼]

Model refinements of magnetic circuits are performed via a subproblem finite element method based on a perturbation technique. An approximate problem considering ideal flux tubes is first solved. It gives the sources for finite element perturbation problems considering all the details of the exterior regions, thus accounting for leakage fluxes. The procedure simplifies both meshing and solving processes. It quantifies the gain given by each model refinement on both local and global quantities. [less ▲]

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See detailConcentration of bovine pregnancy associated glycoprotein in plasma and milk: its application for pregnancy diagnosis in cows
Gajewski, Z.; Melo de Sousa, Noelita ULiege; Beckers, Jean-François ULiege et al

in Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society (2008), 59(Suppl 9), 55-64

Pregnancy diagnosis is an important part in reproduction management of ruminants. The aim of the study was to use a new method for evaluating the bPAG and cPAG in milk and blood bPAG and compare this ... [more ▼]

Pregnancy diagnosis is an important part in reproduction management of ruminants. The aim of the study was to use a new method for evaluating the bPAG and cPAG in milk and blood bPAG and compare this results with the other method for pregnancy diagnosis in the cows. The study was carried out in 220 Holstein Frisian cows. Heparinised blood samples were taken from the jugular vein and stored at -20 degrees C until PAG assay by RIA. For bPAG and cPAG, RIA test, milk samples were homogenized. Pure bPAG was used as a standard tracer described by Zoli et al. (1992). The cows were diagnosed as pregnant by means of USG (Aloka SSD 210) and by rectal palpation. bPAG and cPAG concentration in milk increased after 28 day of pregnancy and showed the rapid increase near the parturition. The same results of bPAG concentration we obtained in the blood samples. The decline of bPAG concentration was faster in the milk than in the blood. The data showed that the RIA method is precise enough to measure PAG concentrations in the maternal blood and milk of cows. The data indicate that milk samples can be used for pregnancy diagnosis in cows. The sensitivity and specificity of RIA measurement of PAG are very high. [less ▲]

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