Lesions cerebrales demyelinisantes decouvertes chez un patient immunocompetent VIH-1+.
; Moutschen, Michel ; Demonty, Jean
in Médecine et Maladies Infectieuses (2008), 38(9), 500-3
We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple ... [more ▼]
We report the case of a 32-year-old immunocompetent HIV patient, presenting with acute demyelinating leukoencephalopathy. The patient displayed clinical and radiological features similar to multiple sclerosis. Histology revealed inflammation with necrosis, demyelination and destruction of axons. Serum tests were negative for various infectious agents as well as specific cultures and PCR. Corticotherapy and many antibiotic treatments failed. Resorption of the lesions occurred after partial excision and highly-active antiretroviral therapy (HAART). No recurrence was noted. This demyelinating cerebral disease was considered as the primary manifestation of HIV infection. HIV implication in the genesis of the process and its perpetuating this condition was suspected, but the mechanism is unclear. Dysimmune consequences related to the early course of HIV infection could be prevented by antiretroviral treatment. This study was the first description of tritherapy effectiveness on HIV related multiple sclerosis (MS)-like illness. [less ▲]Detailed reference viewed: 31 (2 ULg)
Modulation of steroid action: Importance of steroid binding globulins
Scientific conference (2008)Detailed reference viewed: 5 (0 ULg)
Les formules basées sur la créatinine :indiscutable ?
Conference given outside the academic context (2008)Detailed reference viewed: 19 (2 ULg)
Unknown placental glycoprotein J2-45 kDa [Fragment] from Bison bonasus placenta - Access number P85329
; Melo de Sousa, Noelita ; Beckers, Jean-François et al
E-print/Working paper (2008)
N-terminal microsequence obtained after purification and characterization of placental proteins in Bison bonasus. Proteins were submitted to SwissProt databank.Detailed reference viewed: 17 (1 ULg)
Optimalisation des techniques prothetiques de rehabilitation orale grace a l'orthodontie: analyse d'un cas clinique.
Lies, Céline ; ; Limme, Michel et al
in Revue Médicale de Liège (2008), 63(10), 609-14
This clinical case underlines the importance of a multidisciplinary approach, prosthetic and orthodontic, for the achievement of an oral rehabilitation treatment plan. Preliminary orthodontic treatment ... [more ▼]
This clinical case underlines the importance of a multidisciplinary approach, prosthetic and orthodontic, for the achievement of an oral rehabilitation treatment plan. Preliminary orthodontic treatment has significantly improved, the position of some natural teeth, which can serve or not as a prosthetic abutment. This has produced a direct prosthetic benefit by limiting tissue reduction for preparation and by giving a better biomechanical and functional context to the restoration.Thus, after an orthodontic treatment step, lasting a year and a half, using both removable appliance and fixed appliance, prosthetic rehabilitation was possible. This included a fixed prosthesis and a removable prosthesis that gave a very satisfying an esthetic result and good masticatory function. [less ▲]Detailed reference viewed: 229 (19 ULg)
(Inter)subjectification in the Middle English Passive construction
Conference (2008)Detailed reference viewed: 7 (0 ULg)
« Repere etice pentru desfasurarea curei psihanalitice »
in Copoeru, Ion; Szabo, Nicoleta (Eds.) Etică şi cultură profesională (2008)Detailed reference viewed: 7 (0 ULg)
Identification of aphid salivary proteins: a proteomic investigation of Myzus persicae.
Harmel, Nicolas ; ; et al
in Insect Molecular Biology (2008), 17(2), 165-74
The role of insect saliva in the first contact between an insect and a plant is crucial during feeding. Some elicitors, particularly in insect regurgitants, have been identified as inducing plant defence ... [more ▼]
The role of insect saliva in the first contact between an insect and a plant is crucial during feeding. Some elicitors, particularly in insect regurgitants, have been identified as inducing plant defence reactions. Here, we focused on the salivary proteome of the green peach aphid, Myzus persicae. Proteins were either directly in-solution digested or were separated by 2D SDS-PAGE before trypsin digestion. Resulting peptides were then identified by mass spectrometry coupled with database investigations. A homemade database was constituted of expressed sequence tags from the pea aphid Acyrtosiphon pisum and M. persicae. The databases were used to identify proteins related to M. persicae with a nonsequenced genome. This procedure enabled us to discover glucose oxidase, glucose dehydrogenase, NADH dehydrogenase, alpha-glucosidase and alpha-amylase in M. persicae saliva. The presence of these enzymes is discussed in terms of plant-aphid interactions. [less ▲]Detailed reference viewed: 82 (28 ULg)
Indexation du DFG pour la surface corporelle: mythe et réalité.
Conference given outside the academic context (2008)Detailed reference viewed: 29 (4 ULg)
Approche isocinétique des blessures ischio-jambières : jusqu’à la prévention ?
in Abstract book du 5ème Clinic Pré-Sport Rencontres de Médecine du Sport : « Approche isocinétique des blessures ischio-jambières : jusqu’à la prévention ? » (2008)Detailed reference viewed: 93 (12 ULg)
Infectious bovine rhinotracheitis and the epidemiological role of the other ruminant species
Thiry, Julien ; Muylkens, Benoît ; Thiry, Etienne
in Magyar Allatorvosok Lapja = Hungarian Veterinary Journal (2008), 130(1), 116-123Detailed reference viewed: 59 (5 ULg)
Effect of a single 5 mg infusion of zoledronic acid on bone turnover markars vs. oral risedronate (5 mg/day) over 1 year in patients with glucocorticoid-induced osteoporosis
; ; Reginster, Jean-Yves et al
in Osteoporosis International (2008), 19(S2), 376Detailed reference viewed: 9 (1 ULg)
Association between changes in bone mineral density and fracture incidence in postmenopausal osteoporotic women receiving calcium and vitamin D : a 3-year follow-up study
Bruyère, Olivier ; Hiligsmann, Mickaël ; FRANKINET, Pierre et al
in Osteoporosis International (2008), 19(S2), 274Detailed reference viewed: 13 (7 ULg)
Monomeric calgranulins measured by SELDI-TOF mass spectrometry and calprotectin measured by ELISA as biomarkers in arthritis
De Seny, Dominique ; Fillet, Marianne ; Ribbens, Clio et al
in Clinical Chemistry (2008), 54
BACKGROUND: SELDI-TOF mass spectrometry (MS) is a high-throughput proteomic approach with potential for identifying novel forms of serum biomarkers of arthritis. METHODS: We used SELDI-TOF MS to analyze ... [more ▼]
BACKGROUND: SELDI-TOF mass spectrometry (MS) is a high-throughput proteomic approach with potential for identifying novel forms of serum biomarkers of arthritis. METHODS: We used SELDI-TOF MS to analyze serum samples from patients with various forms of inflammatory arthritis. Several protein profiles were collected on different Bio-Rad Laboratories ProteinChip arrays (CM10 and IMAC-Cu(2+)) and were evaluated statistically to select potential biomarkers. RESULTS: SELDI-TOF MS analyses identified several calgranulin proteins [S100A8 (calgranulin A), S100A9 (calgranulin B), S100A9*, and S100A12 (calgranulin C)], serum amyloid A (SAA), SAA des-Arg (SAA-R), and SAA des-Arg/des-Ser (SAA-RS) as biomarkers and confirmed the results with other techniques, such as western blotting, immunoprecipitation, and nano-LC-MS/MS. The S100 proteins were all able to significantly differentiate samples from patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS) from those of patients with inflammatory bowel diseases used as an inflammatory control (IC) group, whereas the SAA, SAA-R, and SAA-RS proteins were not, with the exception of AS. The 4 S100 proteins were coproduced in all of the pathologies and were significantly correlated with the plasma calprotectin concentration; however, these S100 proteins were correlated with the SAA peak intensities only in the RA and IC patient groups. In RA, these S100 proteins (except for S100A12) were significantly correlated with the serum concentrations of C-reactive protein, matrix metalloproteinase 3, and anti-cyclic citrullinated peptide and with the Disease Activity Score (DAS(28)). CONCLUSIONS: The SELDI-TOF MS technology is a powerful approach for analyzing the status of monomeric, truncated, or posttranslationally modified forms of arthritis biomarkers, such as the S100A8, S100A9, S100A12, and SAA proteins. The fact that the SELDI-TOF MS data were correlated with results obtained with the classic calprotectin ELISA test supports the reliability of this new proteomic technique. [less ▲]Detailed reference viewed: 62 (19 ULg)
Culicoides trapping with Rothamsted suction traps before and during the bluetongue epidemic of 2006 in Belgium.
; ; et al
in Preventive Veterinary Medicine (2008), 87(1-2), 74-83
The collection of biting midges was taking place some months before the first bluetongue outbreak in Belgium in August 2006. The Walloon Agricultural Research Centre had been monitoring aphid populations ... [more ▼]
The collection of biting midges was taking place some months before the first bluetongue outbreak in Belgium in August 2006. The Walloon Agricultural Research Centre had been monitoring aphid populations at two sites annually in Belgium (Gembloux and Libramont), using two stationary '12-m' Rothamsted suction traps. For the Gembloux trap, collections of insects captured daily from 11 May 2006 onwards were already available at the time of the outbreak. An examination of these samples revealed the presence of Culicoides, some species of which are considered as potential vectors of the bluetongue virus (BTV). The trapping was therefore extended beyond the normal aphid activity period and the Culicoides captured were identified to species level. From 11 May to 31 December 2006, the Gembloux trap caught 664 Culicoides specimens belonging to 19 species comprising known BTV-vectors. The second trap, at Libramont, was reactivated from 12 September to 13 October and caught 97 specimens belonging to nine species, all of which had been found at the Gembloux site. Among the 19 species identified, four were new to Belgian fauna: Culicoides achrayi, C. deltus, C. lupicaris and C. newsteadi. This paper examines the overall phenology and the physiological status of Culicoides in 2006 before and during the bluetongue epidemic. It discusses the potential of the Rothamsted suction trap to monitor Culicoides. [less ▲]Detailed reference viewed: 34 (7 ULg)
Influence of the Ixodes ricinus tick blood-feeding on the antigen-specific antibody response in vivo.
Menten-Dedoyart, Catherine ; ; Thellin, Olivier et al
in Vaccine (2008), 26(52), 6956-64
The blood meal of hard ticks such as Ixodes ricinus lasts several days. This is made possible by tick salivary factors that inhibit inflammation, haemostasis and the host immune response. We assessed the ... [more ▼]
The blood meal of hard ticks such as Ixodes ricinus lasts several days. This is made possible by tick salivary factors that inhibit inflammation, haemostasis and the host immune response. We assessed the latter on a model of immune response in vivo. A significant reduction of specific IgM and IgG levels was observed in BALB/c mice infested 5 days before injection with bovine serum albumin (BSA) and QuilA but not in mice infested 5 days after the immunization. This effect was not observed in mock-infested mice and could not be attributed to the use of anesthetics. The antibody response was not merely delayed and the Th(1)/Th(2) balance appeared not altered. T-dependent zones and germinal centers in lymph nodes draining the tick bite site showed no apparent morphological alterations or shift in T cell subpopulations. However, the spleens of tick-infested mice had also an enlarged red pulp, indicating an increased extramedullary haematopoietic activity. [less ▲]Detailed reference viewed: 68 (14 ULg)