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See detailEven attenuated bovine leukemia virus proviruses can be pathogenic in sheep.
Florins, Arnaud-Francois ULg; Gillet, Nicolas ULg; Boxus, Mathieu ULg et al

in Journal of virology (2007), 81(18), 10195-200

Based on a reverse genetics approach, we previously reported that bovine leukemia virus (BLV) mutants harboring deletions in the accessory R3 and G4 genes persist at very low proviral loads and are unable ... [more ▼]

Based on a reverse genetics approach, we previously reported that bovine leukemia virus (BLV) mutants harboring deletions in the accessory R3 and G4 genes persist at very low proviral loads and are unable to induce leukemia or lymphoma in sheep, indicating that these R3 and G4 gene sequences are required for pathogenesis. We now show that lymphoma can occur, albeit infrequently (1 case of 20) and after extended periods of latency (7 years). Direct sequencing and reinfection experiments demonstrated that lymphomagenesis was not due to the reversion of the mutant to the wild type. Similar observations with another type of attenuated mutant impaired in the transmembrane protein (TM) YXXL signaling motifs were made. We conclude that the R3 and G4 genes and the TM YXXL motifs are not strictly required for pathogenesis but that their integrity contributes to disease frequency and latency. [less ▲]

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See detailLes titres de traités hippocratiques attestés dans la littérature médicale papyrologique
Marganne, Marie-Hélène ULg

in Studi di Egittologia e di Papirologia (2007), 4

In the literary papyri, the presence of a final, initial, or noted on a label title, not only identifies certainly the contents by giving the ancient name of the work, but is often also, with other ... [more ▼]

In the literary papyri, the presence of a final, initial, or noted on a label title, not only identifies certainly the contents by giving the ancient name of the work, but is often also, with other codicologic peculiarities, the indication of a copy of library. Do the 22 Hippocratic papyri present an indication of this kind? The author tries to answer these questions by examining not only Hippocratic papyri, but also several adespota where are quoted some titles of Hippocratic treatises, sometimes accompanied with the name of their author. [less ▲]

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See detailEpidemiology and genetics of pituitary tumors
Beckers, Albert ULg

Scientific conference (2007)

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See detailAn unusual cell type of the auditory organ during neonatal development: the inner pillar cells
Thelen, Nicolas ULg; Breuskin, I; Malgrange, B et al

Poster (2007)

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See detailL’utilisation du blé dans l’alimentation du poulet de chair en Wallonie
Piron, Fabien ULg; Wéry, Olivier; Bodson, Bernard ULg et al

Conference given outside the academic context (2007)

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See detailSpectroscopic anatomy of a meteor with the very large telescope (ESO)
Jehin, Emmanuel ULg; Jenniskens, P.; Cabanac, R. A. et al

in Advances in Space Research (2007), 39

A meteor spectrum was recorded serendipitously with the ESO Very Large Telescope during a long exposure in long-slit spectroscopic mode with the instrument FORS1. The -8 magnitude fireball crossed the ... [more ▼]

A meteor spectrum was recorded serendipitously with the ESO Very Large Telescope during a long exposure in long-slit spectroscopic mode with the instrument FORS1. The -8 magnitude fireball crossed the narrow (1 arcsec × 7 arcmin) slit during the observation of a high z supernova in normal service mode operation on May 12, 2002. The spectrum covers the range of 637 1050 nm, where the meteor’s air plasma emissions from N[SUB]2[/SUB], N and O dominate. The meteor trail appears moreover resolved along the slit but we conclude that this is because the meteor at 100 km altitude was out of focus for the VLT. The plasma excitation temperature varies only from about 4300 to 4365 K across the trail, based on the ratio of atomic and molecular nitrogen emissions. This is in agreement with the fact that the trail is not actually spatially resolved. Finally, carbon atom emission is not detected in the relatively unexplored range above 900 nm. [less ▲]

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See detail13ième activité du CDS - Evaluation formative
Colaux, Catherine ULg

Report (2007)

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See detailDetecting awareness in impaired states of consciousness
Vanhaudenhuyse, Audrey ULg

Conference (2007)

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See detailApproche neuropsychologique de la prise en charge des stades débutants de la maladie d'Alzheimer
Adam, Stéphane ULg

in Rousseau, Thierry (Ed.) Démences: Orthophonie et autres interventions (2007)

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See detailProject Office - First synthetic report
Warnant, René ULg

Report (2007)

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See detailWorkshop Goederenrecht
Lecocq, Pascale ULg; Sagaert, Vincent

Scientific conference (2007)

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See detailEtudes sédimentologiques dans les cours d’eau à moules perlières en Ardenne
Mols, J.; Defechereux, O.; Petit, François ULg et al

in Rencontres nationales techniques, gestion des ruisseaux de têtes de bassin set zones humides associées (2007)

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See detailDevonian
Boulvain, Frédéric ULg; Wood, R.

in Vennin, E.; Aretz, M.; Boulvain, Frédéric (Eds.) et al Facies from Palaeozoic reefs and bioaccumulations (2007)

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See detailRelevance of nitric oxide for myocardial remodeling.
MASSION, Paul ULg; Balligand, Jean-Luc

in Current Heart Failure Reports (2007), 4(1), 18-25

Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to maladaptive remodeling leading to heart failure. In rodent models of pressure overload or myocardial infarction, the ... [more ▼]

Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to maladaptive remodeling leading to heart failure. In rodent models of pressure overload or myocardial infarction, the three NO synthase (NOS) isoforms were shown to play a neutral, protective, or even adverse role in myocardial remodeling, depending on the quantity of NO produced, the location of each NOS and their regulators, the prevailing oxidant stress and resultant NO/oxidant balance, as well as NOS coupling/dimerization. Beside neuronal NOS and--in specific conditions--inducible NOS isoforms, endothelial NOS (eNOS) exerts cardioprotective effects on pressure-overload, ischemia/reperfusion, and myocardial infarction-induced myocardial remodeling, provided the enzyme remains in a coupled state. Besides its effects on excitation-contraction coupling in response to stretch, eNOS acts as an "endogenous beta-blocker" by restoring the sympathovagal balance, opposing excessive hypertrophy as well as promoting vasodilatation and neoangiogenesis, thereby contributing to tissue repair. As eNOS was also shown to mediate the beneficial effects of cardiovascular drugs commonly used in patients with heart failure, strategies to increase its expression and/or coupled catalytic activity in the myocardium offer new therapeutic avenues for the treatment of this disease. [less ▲]

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See detailA new inhibition task for young children: The “Real Size Animal” task
Catale, Corinne ULg; Meulemans, Thierry ULg

in Books of Conference Abstract: The 9th European Conference on Psychological Assessment (2007)

In neuropsychology, inhibition deficits underlie a variety of cognitive and behavioural dysfunctions and are reported in numerous developmental and acquired disorders (such as Attention Deficit and ... [more ▼]

In neuropsychology, inhibition deficits underlie a variety of cognitive and behavioural dysfunctions and are reported in numerous developmental and acquired disorders (such as Attention Deficit and Hyperactivity Disorders–ADHD). Despite a large body of literature regarding inhibition functioning in adult’s neuropsychology, developmental studies on inhibition remained for a long time scarce. Furthermore, most inhibition tools were originally developed for adults and are of limited interest in children – particularly in pre-school children. In this study, we present a new computerized measure of inhibition suitable to young children. This task includes three conditions. The two first conditions assess speed processing and require children to decide quickly, by pressing a response-key, [1] the real size of animals (bird =small) and [2] the on screen size of black rectangles (big or small). The third condition measures inhibition and requires deciding the real size of animals displayed in congruent (big elephant) or incongruent size (big bird) on the screen. Sixty children without neurological disorders and twelve ADHD children aged from 4 to 10 took part in this study. Our aims were to examine the developmental curve of inhibition abilities and to determine the task’s sensitivity in ADHD children. Results show that this task is particularly suitable to preschooler children and provides a good measure of inhibition development (p<.01). Furthermore, this task appears sensitive to inhibition’s disturbances in ADHD children (p<.05). In conclusion, these preliminary results support the validity of this measure to assess inhibition control in young children and its clinical interest in ADHD children. [less ▲]

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See detailRevue Internationale des Droits de l'Antiquité LV (2007) (parue en septembre 2008)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité [= RIDA] (2007), LIV

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See detailPolymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease.
Georges, Michel ULg; Coppieters, Wouter ULg; Charlier, Carole ULg

in Current opinion in genetics & development (2007), 17(3), 166-76

The expression of at least a third of mammalian genes is post-transcriptionally fine-tuned by approximately 1000 microRNAs (miRNAs), assisted by the RNA silencing machinery, comprising tens of components ... [more ▼]

The expression of at least a third of mammalian genes is post-transcriptionally fine-tuned by approximately 1000 microRNAs (miRNAs), assisted by the RNA silencing machinery, comprising tens of components. Polymorphisms and mutations in the corresponding sequence space (machinery, miRNA precursors and target sites) are likely to make a significant contribution to phenotypic variation, including disease susceptibility. Here we review basic miRNA biology in animals, survey the available evidence for DNA sequence polymorphisms affecting miRNA-mediated gene regulation and thus phenotype, and discuss their possible importance in the determination of complex traits. [less ▲]

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See detailSelf-formation of hierarchical micro-meso-macroporous structures: Generation of the new concept "Hierarchical Catalysis"
Vantomme, A.; Léonard, Alexandre ULg; Yuan, Z.-Y. et al

in Colloids and Surfaces A : Physicochemical and Engineering Aspects (2007), 300(1-2 SPEC. ISS.), 70-78

The self-formation phenomenon of hierarchy with multiple-scaled porosity is reported. The structures of various chemical compositions, such as ZrO2, TiO2, Al2O3, Y2O3, Nb2O5, Ta2O5 ZrO2-SiO2, ZrO2-TiO2 ... [more ▼]

The self-formation phenomenon of hierarchy with multiple-scaled porosity is reported. The structures of various chemical compositions, such as ZrO2, TiO2, Al2O3, Y2O3, Nb2O5, Ta2O5 ZrO2-SiO2, ZrO2-TiO2, ZrO2-Y2O3, aluminosilicates, aluminophosphates, silicoaluminophosphates, metallophosphates, are made of macrochannels (0.5-5 μm in diameter) with mesoporous or microporous walls. The hierarchically porous structures are prepared by just controlling the hydrolysis and polycondensation rates of the pre-selected inorganic sources. The textural, structural as well as morphological properties of each material are carefully studied by using a large series of techniques, such as XRD, NMR, TEM, SEM, N2 adsorption-desorption, Hg porosimetry, optical microscopy. On the basis of these multimodal porous structures, a new concept "Hierarchical Catalysis" has been proposed. This new concept can allow the realisation of a multiple steps reaction in one single catalyst in a cascade way without any separation processes. © 2007 Elsevier B.V. All rights reserved. [less ▲]

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