La mystique de l'Incarnation et de la servitude

in Corbin, Alain; Lemaître, Nicole; Thélamon, Françoise (Eds.) et al Histoire du Christianisme. Pour mieux comprendre notre temps (2007)

Isolation and evaluation of bacteria and fungi as biological control agents against Rhizoctonia solani

Poster (2007)

Rapport de la convention de recherche FR00001481 pour TOTAL

Report (2007)

Exploring the synergy between promoting active participation in work and in society and social, health and long-term care strategies

Report (2007)

The purpose of this study is to provide information that can help the Commission and EU Member States engage in policy discussion on how social, health and long-term care systems can help enhance ... [more ▼]

The purpose of this study is to provide information that can help the Commission and EU Member States engage in policy discussion on how social, health and long-term care systems can help enhance participation in work and family, social and community activities and how, in turn, participation in paid employment, family, social and community activities can contribute to healthy and autonomous living at present and in the future. Part I presents a review of the literature on the synergy between health and activity/work. Health affects work and social participation but on the other side work and activity affect health. We focus on people aged 55 and over as this interrelation (double causality) seems to be significant for important life events (retirement decision, social participation, etc.) of this age group. Part II presents a quantitative analysis and tries to identify national specificities. It presents the lessons which we can draw from European surveys. It presents a quantitative analysis based on the LFS, the EU-SILC, the ECHP UDB and SHARE surveys. The fourth step summarises national policies and gives a comparative analysis, while the fifth step presents the best practices. Finally, the last part summarises the main conclusions and the policy implications. [less ▲]

L'intelligence artificielle et les jeux : cas du Sokoban

Master's dissertation (2007)

His Horses are like Falcons: War Imagery in Ramesside Texts

in Endreffy, Kata; Gulyas, Andras (Eds.) Proceedings of the Fourth Central European Conference of Young Egyptologists (2007)

Optimisation of retrieval strategies using Jungfraujoch high-resolution FTIR observations for long-term trend studies and satellite validation.

in Burrows, J.; Borrell, P. (Eds.) Observing Tropospheric Trace Constituents from Space. (2007)

Field induced metastabilities in U(Ru0.96Rh0.04)(2)Si-2

in Physica C: Superconductivity (2007), 460(Part 1), 682-683

U(Ru0.96Rh0.04)(2)Si-2 is an anisotropic itinerant 5f heavy electron system which exhibits a single field induced magnetic phase concealing a quantum critical point. We show that the boundary of this ... [more ▼]

U(Ru0.96Rh0.04)(2)Si-2 is an anisotropic itinerant 5f heavy electron system which exhibits a single field induced magnetic phase concealing a quantum critical point. We show that the boundary of this phase corresponds to a first order transition as revealed by (1) a large and symmetric specific heat anomaly, (2) an asymmetric magnetocaloric effect on entering and exiting this phase, and (3) a clear history and time-dependent specific heat. We explore the thermodynamic similarities with the mixed valence compound YbInCu4 and show that the out-of-equilibrium properties are analogous to those depicted by the critical state model for hard superconductors. (C) 2007 Elsevier B.V. All rights reserved. [less ▲]

Allocution sur la modernité romantique à l’occasion de la remise du Prix Alfred de Vigny

in Bulletin de l’Association des Amis d’Alfred de Vigny (2007), 36

Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response.

in Experimental hematology (2007), 35(10), 1527-37

OBJECTIVE: Chronic lymphocytic leukemia (CLL) cells develop chemoresistance over time associated with defects in apoptosis pathway. Novel treatment strategies are required to overcome resistance of cells ... [more ▼]

OBJECTIVE: Chronic lymphocytic leukemia (CLL) cells develop chemoresistance over time associated with defects in apoptosis pathway. Novel treatment strategies are required to overcome resistance of cells to commonly used agents. The effects of valproic acid (VPA), an antiepileptic drug with histone deacetylase inhibitory activity, on mononuclear cells isolated from 40 CLL patients were evaluated. METHODS: CLL cells were treated with increasing doses of VPA (0.5, 1, 2, and 5 mM). The mode of cytotoxic drug action was determined by annexin binding, DNA fragmentation, and caspase activation. RESULTS: Exposure of CLL cells to VPA resulted in dose-dependent cytotoxicity and apoptosis in the 40 CLL patients. VPA treatment induced apoptotic changes in CLL cells including phosphatidylserine externalization and DNA fragmentation. The mean apoptotic rates were similar between IgV(H) mutated and unmutated patients, the latter presenting a more aggressive clinical course. VPA induced apoptosis via the extrinsic pathway involving engagement of the caspase-8-dependent cascade. Although CLL cells are commonly resistant to death receptor-induced apoptosis, VPA significantly increased sensitivity of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and led to downregulation of c-FLIP (L) expression. VPA caused no potentialization of TRAIL-induced apoptosis on normal B cells. In addition, VPA overcame the prosurvival effects of bone marrow stromal cells. CONCLUSION: These findings point out that the combination of TRAIL and VPA, at clinically relevant concentration, may be valuable in the treatment of CLL. [less ▲]