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See detailDiagnostic agronomique et agro-environnemental des successions culturales en Wallonie (Belgique).
Leteinturier, Béatrice; Tychon, Bernard ULg; Oger, Robert ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 27-38

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l ... [more ▼]

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l'échelle des régions agricoles qui composent le territoire de la Wallonie (Belgique). L'étude vise à dresser un diagnostic des performances qualitatives des successions culturales, à travers l'analyse individuelle de plusieurs de leurs composantes explicatives telles la qualité des précédents culturaux sur les cultures suivantes, le temps de retour moyen des cultures, le nombre de cultures apparaissant au cours de la succession et enfin la durée des périodes interculturales. Ces quatre composantes sont analysées à l'échelle parcellaire, les résultats étant agrégés au niveau régional. L'étude porte à la fois sur une analyse spatiale basée sur une période de 7 années, ainsi que sur une analyse temporelle visant à observer une éventuelle évolution, région par région, au cours de deux périodes successives de même durée. L'état des lieux ainsi dressé révèle des différences spatiales en termes de pratiques liées aux successions culturales, par contre, une quasi-stabilité dans le temps des paramètres analysés découle des résultats obtenus. Par ailleurs, si ces résultats contribuent à enrichir un état des lieux de l'agriculture en Wallonie, ils peuvent en outre servir de valeurs de référence pour un suivi global de l'évolution des pratiques agricoles régionales. [less ▲]

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See detailDevelopment of an absolute quantification method targeting growth hormone biomarkers using liquid chromatography coupled to isotope dilution mass spectrometry.
Kirsch, Stéphanie ULg; Widart, Joëlle ULg; Louette, Joel et al

in Journal of Chromatography. A (2007), 1153(1-2), 300-6

A method to perform absolute quantification of two biomarkers (IGF-1 and IGFBP-3) of growth hormone abuse has been developed. Isotope dilution is used with synthetically labelled peptides as internal ... [more ▼]

A method to perform absolute quantification of two biomarkers (IGF-1 and IGFBP-3) of growth hormone abuse has been developed. Isotope dilution is used with synthetically labelled peptides as internal standards. Peptide selection and multiple reaction monitoring design are discussed. A simple sample preparation based on the reduction and alkylation of cysteine residues followed by tryptic digestion provides a sufficient digestion of proteins. Serum samples fortified with increasing amounts of target proteins are analysed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) on a triple quadrupole mass spectrometer. Specificity is ensured by the selection of sequences with no homology in BLAST, as well as retention time deviation check, and ion ratio monitoring. Linearity is studied in terms of calibration curves. These curves for IGFBP-3 and IGF-1 are generated with mean slopes of 0.055 and 0.065, intercepts of 0.107 and -0.011, and with coefficients of correlation of 0.95 and 0.98, respectively. These curves result from the addition of proteins to the serum. Risks of variations related to potential matrix effects are therefore reduced, as well as probable variations related to the digestion steps. The working concentration ranges are 4-10 ng/microl for IGFBP-3 and 2-8 ng/microl for IGF-1. Preliminary data regarding repeatability show that relative standard deviations (RSDs) range between 13 and 32% for IGFBP-3 and between 7 and 29% for IGF-1. [less ▲]

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See detailFabrication, characterization, and modeling of strained SOI MOSFETs with very large effective mobility
Driussi, F.; Esseni, D.; Selmi, L. et al

in IEEE (Ed.) 37th European Solid State Device Research Conference (ESSDERC) (2007)

Strained silicon on insulators (sSOI) wafers with a supercritical thickness of 58 nm were produced using thin strain relaxed SiGe buffer layers, wafer bonding, selective etch back and epitaxial overgrowth ... [more ▼]

Strained silicon on insulators (sSOI) wafers with a supercritical thickness of 58 nm were produced using thin strain relaxed SiGe buffer layers, wafer bonding, selective etch back and epitaxial overgrowth. Raman spectroscopy revealed an homogeneous strain of 0.63 plusmn 0.03 % in the strained Si layer. Long channel n-type SOI-MOSFETs showed very large electron mobilities up to 1200 cm2/Vs in the strained Si devices. These values are more than two times larger than those of reference SOI n-MOSFETs. Mobility simulations with state of the art scattering models are then used to interpret the experiments. [less ▲]

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See detailThermal and structural behavior of blends made of palm oil, anhydrous milk fat or their fractions.
Braipson, Sabine ULg; Gibon, Véronique; Deroanne, Claude

Conference (2007)

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See detailmuzeologija : Povijest, razvitak, izazovi danasnjice
Gob, André ULg; Drouguet, Noémie ULg

Book published by Antibarbarus - Prijevod (trad.) Jasna Horn (2007)

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See detailOptimisation of retrieval strategies using Jungfraujoch high-resolution FTIR observations for long-term trend studies and satellite validation.
Mahieu, Emmanuel ULg; Servais, Christian ULg; Duchatelet, Pierre ULg et al

in Burrows, J.; Borrell, P. (Eds.) Observing Tropospheric Trace Constituents from Space. (2007)

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See detailInterface-croquis pour relevés architecturaux: vers la constitution d'une nouvelle activité
Safin, Stéphane ULg; Pecceu, S.; Leclercq, Pierre ULg

in Agon, C.; Delerue, O. (Eds.) Proceedings of the 19th International Conference of the Association Francophone d'Interaction Homme-Machine, IHM (2007)

This article is the synthesis of the ICC research project, aiming at the development of a multimodal and portable interface supporting in real time scale setting of an architectural measurement sketch ... [more ▼]

This article is the synthesis of the ICC research project, aiming at the development of a multimodal and portable interface supporting in real time scale setting of an architectural measurement sketch. Based on a participative process, we first expose and make a model of the traditional activities of measure taking and scale setting. We then describe the ICC software and show how the retooled activity changes, taking into account the help functions it brings. We describe the new structure of measurement activity with scale setting, the new drawing modes it induces. We conclude proposing some tracks for the software improvement. [less ▲]

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See detailLe syndrome Piro-like chez le cheval
Sandersen, Charlotte ULg; Pittel, PH; Amory, Hélène ULg

in Proceedins of the 24th Annual Congress of the Belgian Equine Practitioners Society (BEPS) (2007)

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See detailPhase I/IIclinical trial of local GM-CSF application in patients with cervical HPV-associated low grade squamous intraepithelial lesions
Hubert, Pascale ULg; Doyen, Jean ULg; Chapelle, X. et al

Conference (2007)

Background: Quantitative and functional alterations of professional antigen-presenting cells (APC) in SIL suggest that these lesions may have a diminished capacity to capture viral antigens. Moreover, GM ... [more ▼]

Background: Quantitative and functional alterations of professional antigen-presenting cells (APC) in SIL suggest that these lesions may have a diminished capacity to capture viral antigens. Moreover, GM-CSF (whose production is decreased in HPV-transformed keratinocytes) is an essential factor for the migration of APC in cervical (pre)neoplastic lesions formed in vitro and transplanted in vivo on mouse. In this study we performed a phase I/II clinical trial in order to determine whether a local application of GM-CSF on cervical low-grade squamous intraepithelial lesions (LSIL) might increase the recruitment of APC into the epithelium and indirectly the viral antigen presentation to the immune system. Methods: Fifteen patients with LSIL (10 GM-CSF and 5 placebo) were enrolled in this study. Patients received 4 GM-CSF applications (or placebo gel) and were followed during 6-7 months. APC infiltration was quantified by immunostaining with anti-CD1a mAb. Cellular immune response was evaluated by using an IFN-gamma intracellular staining on PBMC stimulated in vitro with the E7 HPV16 protein and L1 HPV16 Virus-like particles (VLP). Hybrid capture was performed to semi-quantify the viral DNA in cervical brush specimens. Results: GM-CSF applications were well tolerated in all patients. No difference in the cytological/histological and viral parameters assessed at 2 and 6 months after the last application was observed between the GM-CSF and the placebo group. An increased number of CD1a+ APC was observed in 6/10 patients treated by GM-CSF compared to 1/5 patient in the placebo group. There was an increased immune response against HPV in the GM-CSF group showed by NK and T cells producing IFN-gamma. [less ▲]

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See detailEricksonian hypnosis in tinnitus therapy.
Maudoux, Audrey ULg; Bonnet, Sophie ULg; Lhonneux-Ledoux, F. et al

in B-ENT (2007), 3 Suppl 7

OBJECTIVE: To evaluate the effect of Ericksonian therapy on tinnitus STUDY DESIGN: Non-randomised, prospective longitudinal study. SETTING: Tertiary referral centre. PATIENTS: A total of 49 patients ... [more ▼]

OBJECTIVE: To evaluate the effect of Ericksonian therapy on tinnitus STUDY DESIGN: Non-randomised, prospective longitudinal study. SETTING: Tertiary referral centre. PATIENTS: A total of 49 patients underwent hypnosis therapy. Fourteen patients failed to finish the therapy (drop-out rate: 35%). Of the 35 patients who completed the therapy, 20 were male and 15 female. The average age was 46.3 years (range 17-78). INTERVENTION: The treatment is based on the principles and approaches of Ericksonian hypnosis. The first session was mainly dedicated to the evaluation of the impact of tinnitus on the patient's life and to an explanation of hypnosis therapy. The next sessions were "learning sessions" based on relaxation and mental imaging. Exercises were first based on all senses other than hearing. Then they focused on hearing, teaching patients how to modulate sound intensity, and finally how to modulate tinnitus intensity. Patients also learnt self-hypnosis. MAIN OUTCOME MEASURE(S): To evaluate the effect of the treatment, tinnitus was assessed with the Tinnitus Handicap Inventory questionnaire before and after the therapy. Results: After 5 to 10 sessions (mean: 8.09 + -1.92) of Ericksonian hypnosis therapy, the 35 patients were capable of self-hypnosis with the aim of modulating their tinnitus, and the measured THI score fell for all patients. The global score improved significantly from 60:23 before EH therapy to 16.9 at discharge. Within the group, the initial score was distributed as follows: 0% slight, 14% mild, 31% moderate, 31% severe and 23% catastrophic. The t-test for dependent variables revealed significant improvements in all subgroups (p < or = 0.005). CONCLUSIONS: The results of this clinical trial demonstrate that Ericksonian hypnosis, in particular using self-hypnosis, is a promising technique for treating patients with tinnitus. [less ▲]

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See detailL'image du mois. Acanthosis nigricans juvenile.
Szepetiuk, Grégory; Letot, Bernard ULg; Hermanns-Lê, Trinh ULg et al

in Revue Médicale de Liège (2007), 62(4), 181-3

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See detailNouvelles approches dans la prise en charge de l'infection a VIH.
Chandrika, K.; Dellot, Patricia ULg; Frippiat, Frédéric ULg et al

in Revue Médicale de Liège (2007), 62 Spec No

HIV infection remains a major problem of public health in Belgium as well as globally. The number of new diagnosies of HIV infection in Belgium remains between two and three daily. Given the dramatic ... [more ▼]

HIV infection remains a major problem of public health in Belgium as well as globally. The number of new diagnosies of HIV infection in Belgium remains between two and three daily. Given the dramatic effect of antiretroviral therapy on the mortality due to HIV infection, the number of patients is constantly increasing. The different problems related to HIV care are also changing. Aging of the patients and chronic exposure to antiretroviral medications have induced new complications. We will present in this brief article several new experimental and clinical approaches in which our centre has participated during the last two years. [less ▲]

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