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See detailConserved cis-acting elements upstream of genes composing the chitinolytic system of streptomycetes are DasR-responsive elements
Colson, Séverine ULg; Stephan, J.; Hertrich, T. et al

in Journal of Molecular Microbiology and Biotechnology (2007), 12(1-2), 60-66

For soil-dwelling bacteria that usually live in a carbon-rich and nitrogen-poor environment, the ability to utilize chitin -the second most abundant polysaccharide on earth is a decisive evolving ... [more ▼]

For soil-dwelling bacteria that usually live in a carbon-rich and nitrogen-poor environment, the ability to utilize chitin -the second most abundant polysaccharide on earth is a decisive evolving advantage as it is a source for both elements. Streptomycetes are high-GC Gram-positive soil bacteria that are equipped with a broad arsenal of chitinase-degrading genes. These genes are induced when the streptomycetes sense the presence of chitooligosaccharides. Their expression is repressed as soon as more readily assimilated carbon sources become available. This includes for example glucose or N-acetylglucosamine, the monomer subunit of chitin. Historically, the first cis-acting elements involved in carbon regulation in streptomycetes were found more than a decade ago upstream of chitinase genes, but the transcriptional regulator had so far remained undiscovered. In this work, we show that these cis-acting elements consist of inverted repeats with multiple occurrences and are bound by the HutC/GntR type regulator DasR. We have therefore designated these sites as DasR-responsive elements (dre). DasR, which is also the repressor of the genes for the N-acetylglucosamine-specific phosphotransferase transport system, should therefore play a critical role in sensing the balance between the monomeric and polymeric forms of N-acetylglucosamine. Copyright (c) 2007 S. Karger AG, Basel. [less ▲]

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See detailAllergy reactions to insulin: effects of continuous subcutaneous insulin infusion and insulin analogues.
Radermecker, Régis ULg; Scheen, André ULg

in Diabetes/Metabolism Research & Reviews (2007), 23(5), 348-55

The purification of animal insulin preparations and the use of human recombinant insulin have markedly reduced the incidence but not completely suppressed the occurrence of insulin allergy manifestations ... [more ▼]

The purification of animal insulin preparations and the use of human recombinant insulin have markedly reduced the incidence but not completely suppressed the occurrence of insulin allergy manifestations. Advances in technologies concerning the mode of delivery of insulin, i.e. continuous subcutaneous insulin infusion (CSII), and the use of insulin analogues, resulting from the alteration in the amino acid sequence of the native insulin molecule, may influence the immunogenicity and antigenicity of native insulin. Instead of increasing allergy reactions, CSII has been reported to represent a successful alternative treatment in diabetic patients presenting local or generalized allergy to insulin or other components (zinc, protamine) of conventional treatment. Most recent reports concern CSII-treated patients using short-acting insulin analogues (essentially insulin lispro), although the precise role of these insulin analogues remains unclear as allergy to them has also been described. Finally, data on antigenicity and immunogenicity of long-acting insulin analogues (glargine, detemir), which may mimic the basal insulin delivery with CSII, remain scarce at present. [less ▲]

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See detailA stress-strain framework for modelling the behaviour of unsaturated soils under non-isothermal conditions.
François, Bertrand ULg; Lyesse, Laloui

in Springer Proceedings in Physics 113, Theoretical and Numerical Unsaturated Soils Mechanics (2007)

This paper addresses a new, unified thermo-mechanical constitutive model for unsaturated soils through a coupled study. In the context of elastoplasticity and the critical state theory, the model uses the ... [more ▼]

This paper addresses a new, unified thermo-mechanical constitutive model for unsaturated soils through a coupled study. In the context of elastoplasticity and the critical state theory, the model uses the concepts of multimechanism and bounding surface theory. This advanced constitutive approach involves thermo-plasticity of saturated and unsaturated soils. Bishop’s effective stress framework is adopted to represent the stress state in the soil. This stress is linked to the water retention curve, which is represented by an elasto-plastic model. Attention is focused particularly on the coupling relations inferred from this unified thermohydro-mechanical (THM) study. Finally, the theoretical aspects of the paper are supported by comparisons between numerical simulations and experimental results. [less ▲]

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See detailIonoluminiscencia en minerales de interés gemológico
Calvo Del Castillo, Helena ULg; Ruvalcaba Sil, Jose Luis; Millán Chagoyén, Asunción et al

Poster (2007)

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See detailArrangement au présent, compromis au futur. Les ‘cadres de l’expérience’ d’un groupe de jeunes garçons dans le contexte tunisien
Nachi, Mohamed ULg

in Briviglierie et Cicchelli, Marc et Vincenzo (Ed.) Adolescences méditerranéennes. L’espace public à petits pas (2007)

Enquête pour suivre les expériences d’un groupe de jeunes en Tunisie et analyser la manière dont ils s'arrandent entre-eux, se mattent d'accord, nouer des compromis pour pouvoir vivre en commun

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See detailL'image du mois. SAM apres reparation de la valvule mitrale.
Radermecker, Marc ULg; Warzee, F.; Kerzmann, Arnaud ULg et al

in Revue Médicale de Liège (2007), 62(2), 65

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See detailA Reputation-Based Approach for Securing Vivaldi Embedding System
Saucez, Damien; Donnet, Benoît ULg; Bonaventure, Olivier

in 13th Conference on Dependable and Adaptable Networks and Services (2007)

Many large-scale Internet applications optimize their overlay network to reduce latencies. Embedding coordinate systems like Vivaldi are valuable tools for this new range of applications since they ... [more ▼]

Many large-scale Internet applications optimize their overlay network to reduce latencies. Embedding coordinate systems like Vivaldi are valuable tools for this new range of applications since they propose light-weight algorithms that permit to estimate the latency between any pair of nodes without having to contact them first. It has been recently demonstrated that coordinate systems in general and Vivaldi in particular are sensible to attacks. Typically, nodes can lie about their coordinate and distort the coordinate space. In this paper, we propose a formal reputation model to detect misbehaving nodes and propose a reputation adaptation of Vivaldi called RVivaldi. We evaluate the performance of RVivaldi using the King dataset and show that RVivaldi is less sensitive to malicious nodes than Vivaldi. [less ▲]

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See detailRole Of Terpenes From Aphid-Infested Potato On Searching And Oviposition Behavior Of Episyrphus Balteatus
Harmel, Nicolas ULg; Almohamad, Raki; Fauconnier, Marie-Laure ULg et al

in Insect Science (2007), 14(1),

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See detailDes musées au-dessus de tout soupçon
Gob, André ULg

Book published by Armand Colin (2007)

Conservatoires du patrimoine, garants de la mémoire, refuges du Beau, les musées relèvent a priori d’une autre branche de l’activité humaine que la guerre, et plus généralement que l’exercice de la ... [more ▼]

Conservatoires du patrimoine, garants de la mémoire, refuges du Beau, les musées relèvent a priori d’une autre branche de l’activité humaine que la guerre, et plus généralement que l’exercice de la violence… Et pourtant… On s’est bien gardé jusqu’à présent de trop creuser la question, mais ce livre le montre, le musée et la guerre ont fait couple plus souvent qu’à leur tour. Si, de la Campagne d’Italie de 1796 à la récente guerre d’Irak, le musée est trop souvent la victime impuissante de faits de guerre, les situations ne manquent pas non plus où il « s’adapte » un peu trop bien. La convoitise du collectionneur prend le pas sur la responsabilité du conservateur : plus de guerre chez les uns, plus de musée chez les autres… L’impérialisme, le nationalisme, l’idéologie, le manque d’humanité ou la simple ignorance des torts commis aux individus ou aux peuples spoliés se révèlent d’excellents agents muséaux… Retour sur une histoire où rode encore le fantôme de Göring et quelques autres qu’on eût pu croire plus fréquentables, ce livre érudit, captivant et salubre analyse toutes les pièces du dossier : dégâts directs et indirects, saisies, commerce et trafic illicite, restitutions, etc. Fondamentalement honnête, il n’obéit à aucune logique d’imprécation. L’anime plutôt le soupçon que l’idéal qui a donné naissance aux premiers musées doit connaître une relance, au service du patrimoine mondial et de l’homme universel. [less ▲]

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See detailEléments de bioinformatique v3.0
Peulen, Olivier ULg

Learning material (2007)

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See detailSequential Variational Inference for Distributed Multi-Sensor Tracking and Fusion
Du, Wei ULg; Piater, Justus ULg

in The 10th International Conference on Information Fusion (2007)

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See detailInformation-theoretic inference of large transcriptional regulatory networks
Meyer, Patrick ULg; Kontos, Kevin; Lafitte, Frederic et al

in EURASIP Journal on Bioinformatics & Systems Biology (2007), 2007

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See detailIntermittent bisphosphonate therapy in postmenopausal osteoporosis - Progress to date
Reginster, Jean-Yves ULg; Malaise, Olivier ULg; Neuprez, A. et al

in Drugs & Aging (2007), 24(5), 351-359

Bisphosphonates are the most widely prescribed drugs in osteoporosis today. They have unequivocally shown their ability to reduce fracture rate at the spine (alendronic acid, risedronic acid, ibandronic ... [more ▼]

Bisphosphonates are the most widely prescribed drugs in osteoporosis today. They have unequivocally shown their ability to reduce fracture rate at the spine (alendronic acid, risedronic acid, ibandronic acid) and at the hip (alendronic acid and risedronic acid). However, their dosage and administration procedures and the adverse reactions induced by their oral intake are responsible for low adherence. Therefore, intermittent regimens have been developed. Weekly alendronic acid and risedronic acid provide similar benefits, in terms of bone mineral density (BMD) and changes in biochemical markers, as those seen with their daily formulations. Ibandronic acid has been shown to reduce vertebral fractures when given intermittently. Ibandronic acid given orally monthly and intravenously every 2 or 3 months provides increases in BMD similar to the daily formulation. Yearly intravenous infusions of zoledronic acid are currently being evaluated for their ability to reduce fractures. If the efficacy and safety of bisphosphonates given at administration intervals longer than weekly are confirmed, this might significantly improve patient adherence and long-term outcomes of bisphosphonate treatment in postmenopausal osteoporosis. [less ▲]

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See detailL'enfance volée de Kinshasa
Melice, Anne ULg

in Espace de Libertés : Magazine du Centre d'Action Laïque (2007), 349

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See detailClinical differentiation of malignant catarrhal fever, mucosal disease and bluetongue.
Bexiga, R.; Guyot, Hugues ULg; Saegerman, Claude ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2007), 161(25), 858-9

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See detailInventaire des sources statistiques préalable à un observatoire de l'écomonie plurielle
Marée, Michel ULg; Gijselinckx, Caroline

Report (2007)

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See detailHybridization And Morphogenetic Variation In The Invasive Alien Fallopia (Polygonaceae) Complex In Belgium
Tiebre, Ms.; Bizoux, Jean-Philippe ULg; Hardy, Oj. et al

in American Journal of Botany (2007), 94(11), 1900-1910

The invasive alien knotweeds, Fallopia spp. (Polygonaceae), are some of the most troublesome invasive species in Europe and North America. Invasive success in Fallopia may be enhanced by multiple ... [more ▼]

The invasive alien knotweeds, Fallopia spp. (Polygonaceae), are some of the most troublesome invasive species in Europe and North America. Invasive success in Fallopia may be enhanced by multiple hybridization events. We examined the pattern of hybridization and its evolutionary consequences in Belgium with a concerted analysis of ploidy levels (chromosome counts and flow cytometry), morphological variation, and genetic variation (RAPDs). At least four taxa with different ploidy levels were part of the pattern of invasion in Belgium. Hybrid F.3bohemica with various chromosome numbers restored the genotypic diversity that was lacking in the parental species. Hybrid genotypes were mainly assigned to a specific genetic pool and not to a mixture between the genetic pools of the putative parental species as would be expected for hybrids. Parental species and hexaploid hybrids differed significantly for a set of well-defined morphological characters, enabling future researchers to distinguish these taxa. On the basis of our results, the importance of hybridization has probably been underestimated in large parts of the adventive range of alien Fallopia species, pointing to the need for concerted molecular and morphological analyses in the study of the evolutionary consequences of hybridization. [less ▲]

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See detailLandslide detection from remote sensing images using statistical and ANN classification methods
Danneels, Gaëlle; Havenith, Hans-Balder ULg; Pirard, Eric ULg

in Geophysical Research Abstracts (2007)

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