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See detailRégulation et dérégulation de l'âge pubertaire : populations à risque ?
Parent, Anne-Simone ULg; Domine, Françoise ULg; Charlier, Corinne ULg et al

in Revue Médicale de Liège (2007), 62

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See detailChanges of sub-fossil chironomid assemblages associated with volcanic sediment deposition in an Andean lake (38 degrees S), Chile
Araneda, Alberto; Cruces, Fabiola; Torres, Laura et al

in Revista Chilena de Historia Natural (2007), 80(2), 141-156

Chironomid assemblages and sedimentological parameters (grain size, organic content, mineralogy) of a short sediment core from Lake Galletue (38 degrees 41' S, 71 degrees 17' W) were analysed. The ... [more ▼]

Chironomid assemblages and sedimentological parameters (grain size, organic content, mineralogy) of a short sediment core from Lake Galletue (38 degrees 41' S, 71 degrees 17' W) were analysed. The sedimentary record includes one volcanic ash (tephra) layer, which has a completely different composition than the host sediment in terms of organic content, grain size, and mineralogy. According to the geochronology (Pb-210 and Cs-137), this ash layer corresponds to the eruption of Llaima Volcano in 1956-1957. The tephra deposition had an impact on chironomid assemblages producing, among other changes, an increase in Parakiefferiella and a decrease in Ablabesmyia, although no noticeable change was detected in the diversity index. When compared with other studies, our results also show an impact in terms of the presence of chironomid head capsules within the tephra. The presence of these head capsules could result from the effects of percolation, since the coarse grain size of the tephra particles provides large interstitial spaces. The recovery in the abundances of some taxa after the tephra input, suggests the lake is probably restoring the conditions prevailing before the tephra fall. [less ▲]

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See detailExposure factors influencing serum dioxin concentrations in the French dioxin and incinerators study
Frery, N.; Zeghnoun, A.; Sarter, H. et al

in Organohalogen Compounds (2007), 69

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See detailTree diversity in the Miocene forests of western Eurasia
Utescher, T.; Erdei, B.; François, Louis ULg et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (2007), 253(1-2), 226-250

In the present study, published Miocene mega- and microfloral records compiled from a total of 92 localities in Western Eurasia are analysed with respect to diversity of different plant functional types ... [more ▼]

In the present study, published Miocene mega- and microfloral records compiled from a total of 92 localities in Western Eurasia are analysed with respect to diversity of different plant functional types (PFTs). To study spatial diversity patterns and their evolution three time-intervals are selected corresponding to the Langhian (16.3-13.6 Ma), the Serravallian (13.6-11.6), and the earlier part of the Tortonian (11.6-8.5 Ma). First all arboreal species occurring in the floras are classified using a total of 13 different PFTs (functional types of trees and climatically defined subtypes). In a next step, diversity spectra with respect to these PFTs are generated for each site. Cluster analysis is then performed in order to obtain groups of floras with similar spectra that are interpreted in terms of vegetation type. Their spatial distribution in each time-interval is shown in maps. According to these results, zonally arranged patterns are obtained. Broadleaved Deciduous Forests are most important in the higher latitudes while Mixed Mesophytic Forests dominate the mid-latitudes in Western Eurasia. Broadleaved Evergreen Forests are of minor importance in the area of interest. The observed diversity patterns and their changes in time are correlated with spatial climate patterns and the continental palaeoclimate evolution. During the late Miocene cooling, Broadleaved Evergreen Forests completely disappear from the mid-latitudes of Western Eurasia, and Mixed Mesophytic Forests of the mid-latitudes are mostly replaced by broadleaved deciduous vegetation types. In the context of this cooling, a drier season became established in Western Europe during the Tortonian, as is evident from reconstructed arboreal diversity data and precipitation data. In Central Europe, vegetation types indicating permanently humid conditions persisted throughout all the three time-intervals analysed. (C) 2007 Elsevier B.V. All rights reserved. [less ▲]

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See detailLe nouveau divorce par consentement mutuel
Louis, Sophie ULg

in Pire, Didier; Leleu, Yves-Henri (Eds.) La réforme du divorce (2007)

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See detailLong-term effects of JL 13, a potential atypical antipsychotic, on Ionotropic glutamate receptors
Tarazi, Frank I.; Moran-Gates, Taylor; Gardner, Matthew P. et al

in Journal of Molecular Neuroscience (2007), 32(3), 192-198

Changes in ionotropic glutamate (Glu) N-methyl-D-aspartic acid (NMDA), and 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in rat forebrain regions were autoradiographically ... [more ▼]

Changes in ionotropic glutamate (Glu) N-methyl-D-aspartic acid (NMDA), and 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in rat forebrain regions were autoradiographically quantified after continuous infusion of JL 13 [(5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine furnarate] for 28 days using osmotic minipumps, and compared to the effects of representative typical (haloperidol) and atypical (clozapine, olanzapine, and risperidone) antipsychotic drugs from previous studies. Similar to other atypical and not typical antipsychotics, JL 13 decreased labeling of NMDA receptors in medial and lateral caudate-putamen (CPu; by 40%). These findings indicate that downregulation of NMDA receptors by JL 13 and other atypical antipsychotic agents in CPu may contribute to their low risk of extrapyramidal side effects. In addition, and similar to olanzapine and risperidone, JL 13 increased AMPA receptor binding in CPu (by 42%). Changes in AMPA receptors may contribute to psychopharmacological properties of JL 13 and other atypical agents. Similar to clozapine, JL 13 did not alter levels of NMDA and AMPA receptors in hippocampus and entorhinal cortex. Long-term effects of JL 13 on ionotropic Glu receptors, as well as on other dopamine and serotonin receptors, support the atypical antipsychotic profile of this novel agent. [less ▲]

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See detailEtude de la fonction thymique après greffe de cellules souches hématopoïétiques
Hannon, Muriel ULg

Master's dissertation (2007)

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See detailEffects of cyanamide and acetaldehyde accumulation on the locomotor stimulant and sedative effects of ethanol in mice
Tambour, Sophie ULg; Closon, Catherine; Tirelli, Ezio ULg et al

in Behavioural Pharmacology (2007), 18(8), 777-784

Ethanol administration induces both locomotor stimulant and sedative effects depending upon blood ethanol concentrations. Recent studies in rats and mice suggest that acetaldehyde, the first product of ... [more ▼]

Ethanol administration induces both locomotor stimulant and sedative effects depending upon blood ethanol concentrations. Recent studies in rats and mice suggest that acetaldehyde, the first product of ethanol metabolism, might be involved in the expression of both the stimulant and the sedative effects of ethanol. A number of studies have used the drug cyanamide in an attempt to clarify the role of acetaldehyde in the behavioral effects of ethanol. The results of such studies are, however, difficult to interpret because cyanamide is an inhibitor of the enzymes catalase and aldehyde dehydrogenase, two enzymes with opposite effects on brain acetaldehyde concentrations. This study was aimed at clarifying the effects of cyanamide on ethanol-induced locomotor stimulant and sedative effects in Swiss mice. The locomotor stimulant effects of ethanol were measured in standard activity boxes, whereas the sedative effects of ethanol were quantified using the loss of righting reflex procedure. Cyanamide prevented the locomotor stimulant effects of 2 g/kg ethanol, although this was mainly due to a potentiation of the inhibitory effects of ethanol as evidenced by a prolongation of ethanol-induced loss of righting reflex. Additionally, 4-methylpyrazole, an inhibitor of the enzyme alcohol dehydrogenase, prevented these effects of cyanamide. It is concluded that in vivo the effects of cyanamide are predominantly due to the inhibition of the enzyme aldehyde dehydrogenase, rather than to its effects on catalase. [less ▲]

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See detailModelling spray drift using a modified air pollution Gaussian tilting plume model
Stainier, Charles; Destain, Marie-France ULg; Schiffers, Bruno ULg et al

Poster (2007)

The objective of this research is to evaluate a Gaussian tilting plume model that takes into account the spray characteristics of agricultural nozzles to predict drift. The application of this type of ... [more ▼]

The objective of this research is to evaluate a Gaussian tilting plume model that takes into account the spray characteristics of agricultural nozzles to predict drift. The application of this type of model has proved to be effective for aerial pollution applications. To be applied successfully to the spray drift, the model has to give accurate predictions of the deposits regarding the spray and material characteristics as well as the weather parameters. To reach this objective, the model parameters must be correctly set based on appropriate theoretical basis and experimental data. Based on wind tunnel measurements, the effect of the most important characteristics of spray droplets from an agricultural nozzle has been modelled using a Gaussian tilting plume approach by discretizing the different droplet classes. Although the theoretical basis of the model is simple, the predicted drift appeared to be in relatively good agreement with the experimental results. The discrepancies could be explained by poor fitting of the dispersion model parameters. Further work is required to optimise the value of the model parameters. [less ▲]

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See detailElectrophysiological And Behavioral Activity Of Secondary Metabolites In The Confused Flour Beetle, Tribolium Confusum
Verheggen, François ULg; Ryne, C.; Olsson, P.-O. C. et al

in Journal of Chemical Ecology (2007), 33(3), 525-539

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See detailIsolation and Characterisation of a Ruminant Alphaherpesvirus Closely Related to Bovine Herpesvirus 1 in a Free-Ranging Red Deer
Thiry, Julien ULg; Widen, F.; Grégoire, Fabien ULg et al

in BMC Veterinary Research (2007), 3

BACKGROUND: The genus Varicellovirus of the Herpesviridae subfamily Alphaherpesvirinae includes a cluster of viruses antigenically and genetically related to bovine herpesvirus 1 (BoHV-1): namely bovine ... [more ▼]

BACKGROUND: The genus Varicellovirus of the Herpesviridae subfamily Alphaherpesvirinae includes a cluster of viruses antigenically and genetically related to bovine herpesvirus 1 (BoHV-1): namely bovine herpesvirus 5 (BoHV-5), bubaline herpesvirus 1 (BuHV-1), caprine herpesvirus 1 (CpHV-1), cervid herpesviruses 1 (CvHV-1) and 2 (CvHV-2) and elk herpesvirus 1 (ElkHV-1). Considering the serological relationship between these ruminant alphaherpesviruses, several surveys have studied the occurrence of BoHV-1 related virus infection in wild and domestic ruminant species. In this way, a recent investigation has indicated, in Belgium, a high increase in the serological prevalence of BoHV-1 related virus infection in free-ranging red deer population. In this context, it has been decided to investigate the presence of an alphaherpesvirus spreading in the Belgian free-ranging red deer population. RESULTS: The current study reports the first isolation in a free-ranging red deer of a BoHV-1 closely related virus. The isolate was antigenically, genomically and genetically characterised by comparison with several ruminant alphaherpesvirus. Immunofluorescence assays revealed the isolate was antigenically distinct from bovine and caprine alphaherpesviruses. Similarly, BamHI and BstEII restriction analyses demonstrated the genomic difference between the isolate and the other ruminant alphaherpesviruses. Next, the sequencing of selected parts of UL27 and US8 genes showed a high degree of homologies between each BoHV-1 related ruminant alphaherpesvirus and the isolate. Besides the close relationship between all ruminant alphaherpesviruses, the phylogenetic analysis revealed that the isolate clustered with CvHV-1. CONCLUSION: The first isolation of a virus closely related to BoHV-1 in a free-ranging red deer is reported. Data demonstrate that a CvHV-1 strain, named Anlier, circulates in wild red deer in continental Europe. Anlier strain show consistent differences with the virus isolated from Scottish farmed red deer. All together, these results improve our understanding of ruminant alphaherpesviruses. [less ▲]

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See detailEnfer et Paradis : la toxicité de l'oxygène chez les organismes abyssaux
Rees, J. F.; Zal, F.; Thomé, Jean-Pierre ULg

in Océanis (2007), 30.3

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See detailL’«ontologie fondamentale» est-elle une ontologie ou une sémantique ? Note sur la lecture néokantienne de Heidegger
Dewalque, Arnaud ULg

in Daimon : Revista de Filosofia (2007), 40

My aim is to clarify Heidegger's foundational program called "Fundamentalontologie". I show that the critical interpretation given by the neo-Kantian philosopher Rudolf Zocher (a heir of Heinrich Rickert ... [more ▼]

My aim is to clarify Heidegger's foundational program called "Fundamentalontologie". I show that the critical interpretation given by the neo-Kantian philosopher Rudolf Zocher (a heir of Heinrich Rickert) has the merit to emphasize some ambiguities of thos program. Three theses are under examination: 1. the concept of "Fundamentalontologie" is equivocal; 2. the distinction between "grounding theory" and "grounded theory" helps to overcome this equivocity; 3. the "Fundamentalontologie" mainly is a theory of meaning or a semantics. [less ▲]

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See detailLa politique de sûreté dans les organisations
Eggermont, Gilbert; Zwetkoff, Catherine ULg; Brunet, Sébastien ULg et al

(2007)

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See detailSYNOVIOCYTES, NOT CHONDROCYTES, RELEASE FREE RADICALS AFTER CYCLES OF ANOXIA/RE-OXYGENATION
Schneider, Nicole ULg; Mouithys-Mickalad, Ange ULg; Lejeune, Jean-Philippe ULg et al

Poster (2007)

Introduction : An oxidant activity has been implicated in the onset of equine osteoarthritis. Most of the studies have been done on articular chondrocytes, but little is known about the role of ... [more ▼]

Introduction : An oxidant activity has been implicated in the onset of equine osteoarthritis. Most of the studies have been done on articular chondrocytes, but little is known about the role of synoviocytes. Objective : Our aim was to investigate if equine articular chondrocytes, primary synoviocytes or synoviocytes of a continuous cell line are able to produce free radicals after exposure to anoxia and re-oxygenation. Methods : By oxymetry and electron paramagnetic resonance (EPR), we investigated the effects of repeated anoxia/re-oxygenation (A/R) periods on the respiration and production of free radicals by synoviocytes (rabbit HIG-82 cell line and primary equine synoviocytes) and equine articular chondrocytes. Three periods of 20 min anoxia followed by re-oxygenation were applied to 10exp7 cells; O2 consumption was measured before anoxia and after each re-oxygenation. After the last A/R, cellular free radical formation was investigated by EPR spectroscopy with spin trapping technique (n = 3 for each cell line). Results : Both types of synoviocytes showed a high O2 consumption, which was slower after anoxia. By EPR with the spin trap POBN, we proved a free radical formation. Results were similar for equine and rabbit synoviocytes. For chondrocytes, we observed a low O2 consumption, unchanged by anoxia, and no free radical production. Conclusion : These observations suggest an oxidant activity of synoviocytes, potentially important for the onset of osteoarthritis. [less ▲]

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