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See detailNeonatal screening for sickle cell disease in Central Africa: a study of 1825 newborns with a new enzyme-linked immunosorbent assay test
Mutesa, Léon; Boemer, François ULg; Ngendahayo, Louis et al

in Journal of Medical Screening (2007), 14(3), 113-116

Objectives To evaluate the feasibility of systematic neonatal screening for sickle cell disease in the region of Great Lakes in Central Africa using a new approach with limited costs. Methods Between July ... [more ▼]

Objectives To evaluate the feasibility of systematic neonatal screening for sickle cell disease in the region of Great Lakes in Central Africa using a new approach with limited costs. Methods Between July 2004 and July 2006, 1825 newborn dried blood samples were collected onto filter papers in four maternity units from Burundi, Rwanda and the East of the Democratic Republic of Congo. We tested for the presence of haemoglobin C and S in the eluted blood by an enzyme-linked immunosorbent assay (ELISA) test using a monoclonal antibody. All ELISA-positive samples (multiple of the median (MoM) >= 1.5) were confirmed by a simple molecular test. The statistica software version 7.1 was used to create graphics and to fix the MoM cut-off, and the chi(2) of Pearson was used to compare the genotype incidences between countries. Results Of the 1825 samples screened, 97 (5.32%) were positive. Of these, 60 (3.28%) samples were heterozygous for Hb S, and four (0.22%) for Hb C; two (0.11%) newborns were Hb SS homozygotes. Conclusions The lower cost and the high specificity of ELISA test are appropriate for developing countries, and such systematic screening for sickle cell anaemia is therefore feasible. [less ▲]

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See detailLe traitement biologique des maladies inflammatoires à médiation immune. Le cas de la dermatologie et de la rhumatologie
Von Frenckell, Christian ULg; Henno, Audrey ULg; de LA BRASSINNE, Michel ULg et al

in Revue Médicale de Liège (2007), 62(Spec No), 55-62

The pathophysiology and the treatment of diseases with clinical presentation so different as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and psoriasis vulgaris have been ... [more ▼]

The pathophysiology and the treatment of diseases with clinical presentation so different as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and psoriasis vulgaris have been revolutionized by the discovery of common pro-inflammatory effector mechanisms involving TNF-alpha and by the use of targeted therapies, the anti-TNF-alpha antibodies. In the past 10 years, our experience has helped several hundreds of patients who were treated with novel drugs, years before they became routinely available. In parallel tools of metrology were developped that can now be applied to the routine patient. Lastly, clinical research on these new drugs has also generated derived research works allowing the university hospital to satisfactorilly fullfil its specific missions. [less ▲]

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See detailComment interpréter une élévation de la ferritine sérique?
Langlet, P.; Delwaide, Jean ULg

in Revue Médicale de Bruxelles (2007), 28(4), 265-269

The presence of hyperferritinemia has to rule out acquired causes such as chronic inflammatory disorders, hemolytic anemia, liver diseases as hepatitis B or C, alcohol abuse and non alcoholic fatty liver ... [more ▼]

The presence of hyperferritinemia has to rule out acquired causes such as chronic inflammatory disorders, hemolytic anemia, liver diseases as hepatitis B or C, alcohol abuse and non alcoholic fatty liver disease, specially in patients with normal transferrine saturation. Genetic testing for hemochromatosis is systematically indicated in all patients with elevated transferrine saturation. When an iron overload is demonstrated in the absence of these classic causes, second-line genetic testing should be considered to exclude non HFE hemochromatosis. The aim of this paper is to propose a practical algorithm in the diagnosis of hyperferritinemia and to precise the diagnostic and therapeutic management of genetic hemochromatosis. [less ▲]

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See detailLong-Term Feeding Ecology and Habitat Use in Harbour Porpoises Phocoena Phocoena from Scandinavian Waters Inferred from Trace Elements and Stable Isotopes
Fontaine, Michael ULg; Tolley, K. A.; Siebert, U. et al

in BMC Ecology (2007), 7

BACKGROUND: We investigated the feeding ecology and habitat use of 32 harbour porpoises by-caught in 4 localities along the Scandinavian coast from the North Sea to the Barents Sea using time-integrative ... [more ▼]

BACKGROUND: We investigated the feeding ecology and habitat use of 32 harbour porpoises by-caught in 4 localities along the Scandinavian coast from the North Sea to the Barents Sea using time-integrative markers: stable isotopes (delta13C, delta15N) and trace elements (Zn, Cu, Fe, Se, total Hg and Cd), in relation to habitat characteristics (bathymetry) and geographic position (latitude). RESULTS: Among the trace elements analysed, only Cd, with an oceanic specific food origin, was found to be useful as an ecological tracer. All other trace elements studied were not useful, most likely because of physiological regulation and/or few specific sources in the food web. The delta13C, delta15N signatures and Cd levels were highly correlated with each other, as well as with local bathymetry and geographic position (latitude). Variation in the isotopic ratios indicated a shift in harbour porpoise's feeding habits from pelagic prey species in deep northern waters to more coastal and/or demersal prey in the relatively shallow North Sea and Skagerrak waters. This result is consistent with stomach content analyses found in the literature. This shift was associated with a northward Cd-enrichment which provides further support to the Cd 'anomaly' previously reported in polar waters and suggests that porpoises in deep northern waters include Cd-contaminated prey in their diet, such as oceanic cephalopods. CONCLUSION: As stable isotopes and Cd provide information in the medium and the long term respectively, the spatial variation found, shows that harbour porpoises experience different ecological regimes during the year along the Scandinavian coasts, adapting their feeding habits to local oceanographic conditions, without performing extensive migration. [less ▲]

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See detailStrained silicon-on-insulator - Fabrication and characterization
Reiche, M.; Himcinschi, C.; Gösele, U. et al

in 211th ECS Meeting, 2007 (2007)

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See detailLa Cour constitutionnelle, juge de l'administration
Lewalle, Paul ULg

in En hommage à Francis Delpérée, itinéraires d'un constitutionnaliste (2007)

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See detailLes ‘réfugiées de l’intérieur’. Excision et mariage précoce contraint entre la France et le Mali
Razy, Elodie ULg

in Freedman, J. et Valluy, J. ed. (Ed.) Persécutions des femmes. Savoirs, mobilisations, protections (2007)

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See detailÉtude des paramètres opératoires de pressage mécanique des amandes de Vitellaria paradoxa Gaertn C.F. (karité)
Yé, S.; Lebeau, Frédéric ULg; Wathelet, Jean-Paul ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(4), 267-273

Study of the operational parameters of mechanical pressing of almonds of Vitellaria paradoxa Gaertn C.F. (shea tree). Sheabutter is one of the most diffi cult oleaginous resources to extract by ... [more ▼]

Study of the operational parameters of mechanical pressing of almonds of Vitellaria paradoxa Gaertn C.F. (shea tree). Sheabutter is one of the most diffi cult oleaginous resources to extract by traditional way. In Burkina Faso, where production of sheanuts is estimated at 70 000 tons per year, presses manufactured locally are used to improve the production. In order to optimize the handcraft process of sheabutter production, extraction parameters of Vitellaria paradoxa Gaertn C.F. were studied under laboratory controlled conditions on 3 g samples of ground almonds using a uni-axial compression test machine specifi cally instrumented for this purpose. The studied operational parameters were the grinding (unsieved sample 0.5 mm<Ø<5 mm ; sieved samples 0.5 mm<Ø<1 mm ; 1 mm<Ø<2 mm ; 2 mm<Ø<4 mm ; 4 mm<Ø<5 mm), the heating temperature (30; 50; 70; 90; 110; 130; 150°C) and the extraction pressure (7; 10; 13.4; 15; 16.17; 17.44; 20; 22.43 and 25 MPa). The grinding has favourably infl uenced the extraction rate. The fi nest sieved fraction (0.5 mm<Ø<1 mm) presented the highest extraction rate, 84%. When using unsieved samples, the best results were obtained with a heating temperature of 90°C and an extraction pressure of 20 MPa. In these conditions, the extraction rate reached 78% and the chemical characteristics of the sheabutter were not altered. As a result, a signifi cant increase of the handcrafted presses effi ciency could be reached by simple and inexpensive modifi cations as an increase of the pressure applied to the product, by a decrease of the pressing chamber diameter. [less ▲]

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See detailPréface
Pichault, François ULg

in Verstraeten, Michel (Ed.) Consultants en organisation. Stratégies et pratiques de l’intervention (2007)

Highlights the relevance of a sociological approach of the consulting process

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See detailGilles Hayne, le duc de Neuburg et Biagio Marini
Vendrix, Philippe ULg; Corswarem, Emilie ULg; Bianco, Aurelio

in Studi Musicali (2007), XXXVI(2), 363-441

Cet article consiste en l’édition commentée d’une abondante correspondance tenue entre l’un des compositeurs liégeois majeurs du XVIIe siècle, Gilles Hayne et son mécène, le comte palatin du Rhin et duc ... [more ▼]

Cet article consiste en l’édition commentée d’une abondante correspondance tenue entre l’un des compositeurs liégeois majeurs du XVIIe siècle, Gilles Hayne et son mécène, le comte palatin du Rhin et duc de Neubourg, Wolfgang-Wilhelm, figure importante de la vie politique et culturelle du Saint-Empire. Outre ses fonctions de Surintendant de la musique du duc, Hayne s’illustre comme Maître de chapelle du prince-évêque Ferdinand de Bavière, et comme Grand chantre de la collégiale Saint-Jean de Liège. La correspondance jette un éclairage sur le mécénat aristocratique durant les premières décennies du XVIIe siècle dans le Saint-Empire et sur les échanges noués entre Liège et le duché de Neubourg, l’un des rares îlots de relative quiétude en cette période pour la moins troublée. De nombreux artistes bénéficient du mécénat du duc de Neubourg, de van Dyck à Rubens, de Hayne à Biagio Marini, autre personnalité importante de l’Europe musicale mise en évidence par la correspondance. [less ▲]

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See detailInvasion by Fallopia japonica increases topsoil mineral nutrient concentrations
Dassonville, Nicolas; Vanderhoeven, SONIA ULg; Gruber, Wolf et al

in Ecoscience (2007), 14(2), 230-240

Fallopia japonica is one of the most troublesome alien invasive plants across temperate regions, with large negative impacts on plant species diversity. We examined its impacts on topsoil chemistry and ... [more ▼]

Fallopia japonica is one of the most troublesome alien invasive plants across temperate regions, with large negative impacts on plant species diversity. We examined its impacts on topsoil chemistry and nutrient stocks in standing biomass at 6 sites with contrasting resident plant communities in Belgium. Topsoil and biomass were sampled in invaded and closely adjacent uninvaded plots. Standing biomass and mineral nutrient concentrations in soil (ammonium acetate exchangeable cations and P, total C, and N) and plants were determined. Soil under F. japonica generally had higher exchangeable nutrient concentrations (Cu: +45%, K: +34%, Mg: +49%, Mn: +61%, P: +44%, Zn: +75%). Standing biomass was 3- to 13-fold higher depending on site. Despite lower nutrient concentrations in aboveground biomass, invaded stands had 3.2- to 5.4-fold larger nutrient stocks in aboveground biomass compared to the resident vegetation. We conclude that F. japonica enhances nutrient cycling rates and topsoil fertility, probably due to nutrient uplift. The impacts were greatest in sites with low nutrient concentrations in uninvaded plots, suggesting that F. japonica may contribute to soil homogenization in invaded landscapes. [less ▲]

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See detailComparison of cross-field pitting in fresh, dried and charcoalified softwoods
Gerards, Thomas ULg; Damblon, Freddy ULg; Wauthoz, B. et al

in Iawa Journal (2007), 28(1), 49-60

Cross-field pitting is one of the most reliable characters for softwood identifi cation. During charcoalification, a range of severe qualitative and quantitative modifications may occur in cross-field ... [more ▼]

Cross-field pitting is one of the most reliable characters for softwood identifi cation. During charcoalification, a range of severe qualitative and quantitative modifications may occur in cross-field pitting. As most fossil or archaeological wood remains are preserved as charcoal (fusain), the question arises whether these modifications hamper the accurate identification of some taxa. This work is a systematic biometric study of a wide range of gymnosperm cross-field pitting after experimental charcoalification. We focused on the window-like, piceoid, taxodioid, cupressoid, araucarioid and podocarpoid cross-field pitting types. Our main results are the following: 1) Cross-field pits of wood specimens dried out before charcoalification are hidden by a thin closing wall; in this case, it is often impossible to discriminate between the various types of cross-field pitting. 2) Piceoid cross-field pitting becomes taxodioid-like after charcoalification. 3) Biometric study of charred softwood cross-field pitting dimensions shows that the ratios between height and width of pit aperture and border allow us to distinguish and characterise four types of pitting (window-like, piceoid, taxodioid, cupressoid + araucarioid + podocarpoid [= CAP]). The discrimination within the CAP type requires further investigation. [less ▲]

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See detailLeadership et modèles de gestion des ressources humaines
Pichault, François ULg

in Cobbut, Eric (Ed.) Vers un leadership de qualité. Rêve ou réalité ? (2007)

Studies the contextual conditions under which a quality-based leadership may be efficient

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See detailNaming actions and objects in bilingual aphasia : a multiple case study
Poncelet, Martine ULg; Majerus, Steve ULg; Raman, Ilhan et al

in Brain & Language (2007), 103

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See detailCompétences et identité professionnelles : L’enseignement et autres métiers de l’interaction humaine
Beckers, Jacqueline ULg

Book published by De Boeck Université (2007)

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See detailCONTRÔLES ET GARANTIES : LA FILIÈRE PLANCHE
Defays, Emmanuel; Jourez, Benoît ULg

in Forêt Wallonne (2007), 88

Origine du bois et gestion forestière, caractéristiques et performances du produit, mise en oeuvre… les lignes qui viennent font le point sur les garanties dont bénéficie le consommateur et leurs ... [more ▼]

Origine du bois et gestion forestière, caractéristiques et performances du produit, mise en oeuvre… les lignes qui viennent font le point sur les garanties dont bénéficie le consommateur et leurs implications pour les professionnels. [less ▲]

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See detailCaroline Spurgeon and her Relationship to Chaucer. The Text of her Viva Presentation at the Sorbonne
Dor, Juliette ULg

in Summerfield, Théa; Busby, Keith (Eds.) People and Texts. Relationships in Medieval Literature (2007)

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See detailLes bêtabloquants sont-ils encore des medicaments de premier choix pour le traitement de l'hypertension arterielle non compliquee?
Krzesinski, Jean-Marie ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2007), 62(5-6, May-Jun), 254-7

Arterial hypertension is a significant risk factor for cardiovascular disease, proportional to the blood pressure level. Treating hypertension reduces the risk. Until recently, beta-blockers were ... [more ▼]

Arterial hypertension is a significant risk factor for cardiovascular disease, proportional to the blood pressure level. Treating hypertension reduces the risk. Until recently, beta-blockers were considered as a first line class for hypertension management. The British Hypertension Society has recently pronounced that using beta-blockers as first line antihypertensive therapy is no good choice since these agents are less protective than other antihypertensive classes against cardiovascular disorders and diabetes mellitus, especially when used in association with diuretics. [less ▲]

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