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See detailRelationship between muscular performances of the shoulder and morphostatic profile
Forthomme, Bénédicte ULg; Arimont, A.; Bregonzio, Jany et al

in Isokinetics & Exercise Science (2007), 15

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See detailAttention to self-referential stimuli: Can I stop looking at myself?
Devue, Christel ULg; Jamaer, Nathalie; Brédart, Serge ULg

in Perception (2007), 36(Suppl. S),

Auto-referential materials (own name) have been described as particularly prone to capture attention. Some recent studies by Harris and Pashler (2004 Psychological Science 15 171 - 178) and Gronau et al ... [more ▼]

Auto-referential materials (own name) have been described as particularly prone to capture attention. Some recent studies by Harris and Pashler (2004 Psychological Science 15 171 - 178) and Gronau et al (2003 Journal of Experimental Psychology: General 132 512 - 529) have questioned this view and showed that these own-name effects are temporary and appear only in specific conditions: when enough resources are available or when the own name is a task-irrelevant stimulus presented in the focus of attention. In the present study, a stimulus that is unique to each individual was used: the self-face. In experiment 1, the self-face produced a temporary distraction when presented at fixation during a digit-parity task. However, this distraction was not different from that triggered by another highly familiar face. In experiment 2, familiar faces failed to produce interference when presented outside the focus of attention. Experiment 3, using a less demanding task, indicated that when few resources are required, the self-face may interfere even when presented peripherally. These results confirm recent findings showing that auto-referential materials are special only in specific conditions. [less ▲]

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See detailp27Kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.
Nguyen, Laurent ULg; Besson, A.; Heng, J Ik-Tsen et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2007), 162(5-6), 310-4

The generation of glutamatergic neurons by stem and progenitor cells is a complex process involving the tight coordination of multiple cellular activities, including cell cycle exit, initiation of ... [more ▼]

The generation of glutamatergic neurons by stem and progenitor cells is a complex process involving the tight coordination of multiple cellular activities, including cell cycle exit, initiation of neuronal differentiation and cell migration. The mechanisms that integrate these different events into a coherent program are not well understood. Here we show that the cyclin-dependent kinase inhibitor p27Kip1 plays an important role in neurogenesis in the mouse cerebral cortex, by promoting the differentiation and radial migration of cortical projection neurons. Importantly, p27Kip1 promotes neuronal differentiation and neuronal migration via two distinct mechanisms, which are themselves independent of the cell cycle regulatory function of p27Kip1. p27Kip1 inactivation by gene targeting or RNA interference results in neuronal differentiation and radial migration defects, demonstrating that p27Kip1 regulates cell migration in vivo. The differentiation defect, but not the migration defect, is rescued by overexpression of the proneural gene Neurogenin 2. p27Kip1 acts by stabilizing Neurogenin 2 protein, an activity carried by the N-terminal half of the protein. The migration defect resulting from p27Kp1 inactivation is rescued by blocking RhoA signalling, an activity that resides in the c-terminal half of p27Kip1. Thus, p27Kip1 plays a key role in cortical development, acting as a modular protein that independently regulates and couples multiple cellular pathways contributing to neurogenesis. [less ▲]

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See detailFédéralisme
Beaufays, Jean ULg; Matagne, Geoffroy ULg

in Bourdeau; Merrill (Eds.) DicoPo : Dictionnaire de théorie politique (2007)

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See detailProtein crystallisation under microgravity conditions: What did we learn on TIM crystallisation from the Soyuz missions?
MAES, D.; DECANNIERE, K.; ZEGERS, I. et al

in Microgravity Science and Technology (2007), XIX(5/6), 90-94

The protein Triose Phosphate Isomerase from the hyperthermophilic organism Thermotoga maritima was crystallised on board of the International Space Station in the framework of the Soyuz missions. In this ... [more ▼]

The protein Triose Phosphate Isomerase from the hyperthermophilic organism Thermotoga maritima was crystallised on board of the International Space Station in the framework of the Soyuz missions. In this paper we report on the scientific results obtained during these flights. Firstly it qas shown that different crystal forms for the same protein in the same crystallisation conditions, what is presumably due to a change in the rate at which supersaturation is achieved. Secondly, the X-ray qualité of the crystals grown in the ISS is superior to their ground control crystals. Mimicking microgravity on ground, by adding a small amourt of gel to avoid convection, also results in an improvement of X-ray quality. Nevertheless our analysis shows that the crystals obtained in this gelled ground environment are of inferior quality as compared to their space homologues. Finally we observed movement of crystals grown in the International Space Station, not only because of g-jitters but also due to residual accelerations. This has an important effect on concentration gradients of precipiants and therefore on the solubility of the protein. [less ▲]

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See detailEffect of aggressive encounters on plasma progesterone, corticosterone and corticosteroid binding capacity
Charlier, Thierry ULg; Hammond, Geoffrey L; Soma, Kiran K

Poster (2007)

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See detailThe epidemiology and management of pituitary incidentalomas
Daly, Adrian ULg; Burlacu, M. C.; Livadariu, E. et al

in Hormone Research (2007), 68(Suppl. 5), 195-198

Prevalence: The prevalence of pituitary tumors has been a topic of controversy for many years. Autopsy and radiological series show that pituitary incidentalomas may be present in one of six people ... [more ▼]

Prevalence: The prevalence of pituitary tumors has been a topic of controversy for many years. Autopsy and radiological series show that pituitary incidentalomas may be present in one of six people. Recent epidemiological data suggest that clinically apparent pituitary adenomas have a prevalence of approximately one in 1,000 people in the general population. The disconnect between these two prevalence rates underlines the common clinical quandary of how to manage pituitary incidentalomas, particularly those lacking clinical signs/symptoms or hormonal abnormalities. Management: The natural history of incidentalomas suggests that periodic hormonal, clinical and radiological follow-up is the optimal approach. In the absence of tumor growth or relevant symptoms, screening can be continued intermittently or curtailed based on the clinical judgment of the physician. In the presence of hormonal hypersecretion, the management of pituitary incidentalomas, whether they are micro- or macroadenomas, should follow accepted clinical guidelines. For incidental pituitary macroadenomas without hormonal hypersecretion, clinical management should also include assessments for visual field impairment or hypopituitarism. In such cases, regular radiological and hormonal follow-up is required to identify tumor growth or the appearance of new symptoms. In the presence of tumor growth or new hormonal abnormalities, surgical options should be considered and discussed with the patient. Copyright (C) 2007 S. Karger AG, Basel. [less ▲]

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See detailSome Similar International Approaches for Engaging Instructors in Scholary Teaching and Conducting Research About Teaching
Cox, Milton; Olsson, Thomas; Poumay, Marianne ULg et al

in Enhancing Higher Education, Theory and Scholarship : Proceeding of the 30th HERDSA Annual Conference (2007)

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See detailL'arrêt Cottin c. Belgique ou l'irrésistible marche vers l'expertise contradictoire en matière pénale
Jacobs, Ann ULg

in Revue Trimestrielle des Droits de l'Homme (2007), 69

état de la question de du caractère contradictoire ou non de l'expertise en matière pénale en procédure pénale belge.

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See detailExiste-t-il une "memoire therapeutique" en prevention cardiovasculaire?
Scheen, André ULg

in Revue Médicale Suisse (2007), 3(122), 1864-61868-9

The prevention of type 2 diabetes and of cardiovascular diseases is a major public health objective. Obviously life-style changes play a major role in this strategy. The Finnish Prevention Study recently ... [more ▼]

The prevention of type 2 diabetes and of cardiovascular diseases is a major public health objective. Obviously life-style changes play a major role in this strategy. The Finnish Prevention Study recently demonstrated that the remarkable diabetes prevention observed after a 4-year lifestyle intervention is maintained after a further 3-year period of follow-up without prolongation of the active intervention. Such a reminiscent effect may also be observed in the prevention of cardiovascular diseases with various pharmacological interventions: an ACE inhibitor (HOPE), a statin (4S), a fibrate (Helsinki Heart Study) or an intensive insulin therapy in type I diabetic patients (DCCT-EDIC). These intriguing results argue for a long-term memory of previous therapeutic interventions in cardiovascular prevention. [less ▲]

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See detailSimplicius lecteur du "Sophiste". Contribution à l'étude de l'exégèse néoplatonicienne tardive
Gavray, Marc-Antoine ULg

Book published by Klincksieck (2007)

Ce livre explore la méthode et l’interprétation du Sophiste par Simplicius, en tant qu’elles illustrent l’exégèse néoplatonicienne tardive et entraînent une restauration de la lettre du texte. À partir ... [more ▼]

Ce livre explore la méthode et l’interprétation du Sophiste par Simplicius, en tant qu’elles illustrent l’exégèse néoplatonicienne tardive et entraînent une restauration de la lettre du texte. À partir d’un corpus issu des commentaires (largement inédit en français), Marc-Antoine Gavray reconstruit la lecture de Simplicius et la met en regard avec celles de Plotin, de Proclus et de Damascius. Il en ressort une exégèse attentive, digne d’accompagner le lecteur moderne dans sa compréhension de Platon. [less ▲]

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See detailEffect Of Extraction Conditions On The Yield, Purity And Surface Properties Of Sugar Beet Pulp Pectin Extracts
Yapo, Marcel Beda; Robert, Christelle; Etienne, Isabelle et al

in Food Chemistry (2007), 100(4), 1356-1364

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See detailGlitazones et insuffisance cardiaque: resultats des etudes PROactive, ADOPT, DREAM et RECORD.
De Flines, Jenny ULg; Scheen, André ULg

in Revue Médicale Suisse (2007), 3(122), 18761878-83

Thiazolidinediones (TZDs) are used as insulin sensitizers in the treatment of type 2 diabetes, but are associated with an increased risk of congestive heart failure (CHF). The odds ratio of ICC was 1.43 ... [more ▼]

Thiazolidinediones (TZDs) are used as insulin sensitizers in the treatment of type 2 diabetes, but are associated with an increased risk of congestive heart failure (CHF). The odds ratio of ICC was 1.43 (pioglitazone vs placebo) in diabetic patients with high cardiovascular risk in the PROactive trial while it averaged 1.22 (rosiglitazone vs metformin) and 2.20 (rosiglitazone vs metformin) in the ADOPT study. In the interim analysis of the ongoing RECORD trial, the odds ratio averaged 2.15 (rosiglitazone vs metformin or sulfonylureas). In four real life registries, the relative risk of CHF with TZDs varied between 1.06 and 1.76 (between 1.10 and 1.44 combined with insulin) as compared to a treatment without TZDs. Such higher CHF risk should be appreciated according to the potential benefits of glitazones in the management of type 2 diabetes. [less ▲]

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See detailCaractères généraux des matériaux
Courard, Luc ULg

Learning material (2007)

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See detailRefinement of two female fertility QTL using alternative phenotypes in French Holstein dairy cattle.
Guillaume, F.; Gautier, M.; Ben Jemaa, S. et al

in Animal Genetics (2007), 38(1), 72-4

Two quantitative trait loci (QTL) affecting female fertility were mapped in French dairy cattle. Phenotypes were non-return rates at 28, 56, 90 and 282 days after insemination. On chromosome 3, a QTL was ... [more ▼]

Two quantitative trait loci (QTL) affecting female fertility were mapped in French dairy cattle. Phenotypes were non-return rates at 28, 56, 90 and 282 days after insemination. On chromosome 3, a QTL was significant at 1% for non-return rate at 90 days, suggesting that it affects early fertility events. An analysis of SLC35A3, which causes complex vertebral malformation, excluded this gene from the QTL interval. On chromosome 7, a QTL was almost significant (P = 0.05) for non-return rate at 282 days. This QTL was associated with abortion and stillbirth problems. Use of appropriate phenotypes appeared important for fine-mapping QTL associated with fertility. [less ▲]

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See detailOccurrence of perfluorooctane sulfonate and other perfluorinated alkylated substances in harbor porpoises from the Black Sea
Van de Vijver, Kristin Inneke; Holsbeek, Ludo; Das, Krishna ULg et al

in Environmental Science & Technology (2007), 41(1), 315-320

Perfluorooctane sulfonate (PFOS) and other perfluorinated alkylated substances (PFAS) were determined in liver, kidney, muscle, brain, and blubber samples of 31 harbor porpoises (Phocoena phocoena relicta ... [more ▼]

Perfluorooctane sulfonate (PFOS) and other perfluorinated alkylated substances (PFAS) were determined in liver, kidney, muscle, brain, and blubber samples of 31 harbor porpoises (Phocoena phocoena relicta) of different age and sex stranded along the Ukrainian coast of the Black Sea. In all individuals and in all tissues, PFOS was the predominant PFAS, accounting for on average 90% of the measured PFAS load. PFOS concentrations were the highest in liver (327 +/- 351 ng/g wet wt) and kidney (147 +/- 262 ng/g wet wt) tissue, and lower in blubber (18 +/- 8 ng/g wet wt), muscle (41 +/- 50 ng/g wet wt), and brain (24 +/- 23 ng/g wet wt). No significant differences could be determined between males and females, nor between juvenile and adult animals (p > 0.05). Perfluorononanoic acid, perfluorodecanoic acid, perfluoroundecanoic acid, and perfluorododecanoic acid could be detected in liver tissue of approximately 25% of the individuals. Perfluorobutane sulfonate, perfluorobutanoic acid, and perfluorooctanoic acid were not detected in any of the porpoise livers. Although we investigated a potential intraspecies segregation according to the source of prey, using stable isotopes, no statistically significant correlation between PFOS concentrations and stable isotopes could be determined. It is, however, noteworthy that the contamination by PFOS in the Black Sea harbor porpoises is comparable to levels found in porpoises from the German Baltic Sea and from coastal areas near Denmark and, therefore, might pose a threat to this population. [less ▲]

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See detailCharacterization of the DGAT1 K232A and variable number of tandem repeat polymorphisms in French dairy cattle.
Gautier, M.; Capitan, A.; Fritz, S. et al

in Journal of Dairy Science (2007), 90(6), 2980-8

A quantitative trait locus (QTL) underlying different milk production traits has been identified with a high significance threshold value in the genomic region containing the acylCoA:diacylglycerol ... [more ▼]

A quantitative trait locus (QTL) underlying different milk production traits has been identified with a high significance threshold value in the genomic region containing the acylCoA:diacylglycerol acyltransferase (DGAT1) gene, in the 3 main French dairy cattle breeds: French Holstein, Normande, and Montbeliarde. Previous studies have confirmed that the K232A polymorphism in DGAT1 is responsible for a major QTL underlying several milk production traits in Holstein dairy cattle and several other bovine breeds. In this study, we estimate the frequency of the 2 alternative alleles, K and A, of the K232A polymorphism in French Holstein, Normande, and Montbeliarde breeds. Although the K allele segregates in French Holstein and Normande breeds with a similar effect on production traits, the existence of additional mutations contributing to the observed QTL effect is strongly suggested in both breeds by the existence of sires heterozygous at the QTL but homozygous at the K232A polymorphism. One allele at a variable number of tandem repeats (VNTR) locus in the 5' noncoding region of DGAT1 has been recently proposed as a putative causative variant. In our study, this marker was found to present a high mutation rate of 0.8% per gamete and per generation, making the allele diversity observed compatible with that expected under neutrality. Moreover, among the sires homozygous at the K232A polymorphism, no allele at the VNTR can fully explain their QTL status. Finally, no allele at the VNTR was found to be significantly associated with the fat percentage variation in the 3 breeds simultaneously after correction for the effect of the K232A polymorphism. Therefore, our results suggest the existence of at least one other causative polymorphism not yet described. Because the A allele is nearly fixed in the Montbeliarde breed, this breed represents an interesting model to identify and confirm other mutations that have a strong effect on milk production traits. [less ▲]

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See detailFeline herpesvirus 1, the causative agent of feline viral rhinotracheitis
Costes, Bérénice ULg; Van Den Brande, A.; Thiry, Etienne ULg et al

in Annales de Médecine Vétérinaire (2007), 73

Infectious respiratory diseases also called ‘cat flu’ are nowadays one of the most relevant areas of feline medicine. Epidemiologic surveys revealed that 80% of the cases are due to feline calicivirus and ... [more ▼]

Infectious respiratory diseases also called ‘cat flu’ are nowadays one of the most relevant areas of feline medicine. Epidemiologic surveys revealed that 80% of the cases are due to feline calicivirus and Felid herpesvirus 1 (FeHV-1). FeHV-1 is an alphaherpesvirus that has a worldwide distribution in cat population. It is responsible for feline viral rhinotracheitis. This disease can be acute, chronic or latent. It is characterized by fever and respiratory or ocular signs among which conjunctivitis and keratitis are the most common. Severe cases can cause complete blindness of the cat mostly following repetitive reactivations. Latent viral carriers are epidemiologically important because they are the main source of infection to susceptible cats. Nowadays no vaccine can prevent infection. At best, available vaccines help to reduce clinical signs but fail to prevent establishment of latency or reactivation. Consequently, feline viral rhinotracheitis still represents a major problem in domestic cats. This review focuses on the current knowledge about feline viral rhinotracheitis and its etiologic agent, FeHV-1. [less ▲]

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See detailPlace de l'isocinétisme dans la rééducation des instabilités d'épaule
Croisier, Jean-Louis ULg; Gremeaux, V.; Forthomme, Bénédicte ULg

in Codine, P.; Hérisson, C. (Eds.) Instabilité de l'épaule et médecine de rééducation (2007)

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See detailInstabilité de l'épaule : faillite de la contention musculaire active ? Apport de l'évaluation isocinétique
Gremeaux, V.; Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg

in Codine, P.; Hérisson, C. (Eds.) Instabilité de l'épaule et médecine de rééducation (2007)

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