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See detailMolecular organization of surfactin-phospholipid monolayers: Effect of phospholipid chain length and polar head
Bouffioux, O.; Berquand, A.; Eeman, M. et al

in Biochimica et Biophysica Acta - Biomembranes (2007), 1768(7), 1758-1768

Mixed monolayers of the surface-active lipopeptide surfactin-C-15 and various lipids differing by their chain length (DMPC, DPPC, DSPC) and polar headgroup (DPPC, DPPE, DPPS) were investigated by atomic ... [more ▼]

Mixed monolayers of the surface-active lipopeptide surfactin-C-15 and various lipids differing by their chain length (DMPC, DPPC, DSPC) and polar headgroup (DPPC, DPPE, DPPS) were investigated by atomic force microscopy (AFM) in combination with molecular modeling (Hypermatrix procedure) and surface pressure-area isotherms. In the presence of surfactin, AFM topographic images showed phase separation for each surfactin-phospholipid system except for surfactin-DMPC, which was in good agreement with compression isotherms. On the basis of domain shape and line tension theory, we conclude that the miscibility between surfactin and phospholipids is higher for shorter chain lengths (DMPC > DPPC > DSPC) and that the polar headgroup of phospholipids influences the miscibility of surfactin in the order DPPC > DPPE > DPPS. Molecular modeling data show that mixing surfactin and DPPC has a destabilizing effect on DPPC monolayer while it has a stabilizing effect towards DPPE and DPPS molecular interactions. Our results provide valuable information on the activity mechanism of surfactin and may be useful for the design of surfactin delivery systems. (c) 2007 Elsevier B.V. All rights reserved. [less ▲]

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See detailLa ensenanza de la geografia
Merenne-Schoumaker, Bernadette ULg

in Hiernaux, Daniel; Lindon, Alicia (Eds.) Tratado de Geografia Humana (2007)

Cet article inséré dans un manuel universitaire mexicain cherchant à dresser un bilan de la situation de la géographie humaine aujourd'hui se veut une réflexion générale de ce qu’est et devrait être ... [more ▼]

Cet article inséré dans un manuel universitaire mexicain cherchant à dresser un bilan de la situation de la géographie humaine aujourd'hui se veut une réflexion générale de ce qu’est et devrait être l’enseignement de la géographie au niveau du secondaire et ce au départ de près de 30 ans de recherche en didactique de la géographie. Cette réflexion s’articule autour de quatre questions fondamentales : quels objectifs ? quelles acquisitions de base ? comment enseigner ? comment évaluer les acquis ? [less ▲]

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See detailCharacteristics of familial isolated pituitary adenomas (FIPA) - Review
Daly, Adrian ULg; Vanbellinghen, Jean-François ULg; Beckers, Albert ULg

in Expert Review of Endocrinology & Metabolism (2007), 2(6), 725-733

The familial occurrence of pituitary adenomas has been recognized for many years and currently accounts for approximately 5% of all cases. Molecular, genetic and clinical features of familial pituitary ... [more ▼]

The familial occurrence of pituitary adenomas has been recognized for many years and currently accounts for approximately 5% of all cases. Molecular, genetic and clinical features of familial pituitary adenomas have been well characterized in multiple endocrine neoplasia type 1 (MEN-1) and Carney's complex (CNC), which account for the majority of familial pituitary tumor cases. These conditions are caused by MEN1 and PRKAR1A gene mutations, respectively, and the clinical and pathological features of pituitary pathology in these diseases differ from those of sporadic pituitary tumors. Familial acromegaly has been recognized for many years and, more recently, the clinical features of this clinical phenotype, referred to as isolated familial somatotropinoma, have been clarified. Over the past decade, the concept of non-MEN-1/CNC familial pituitary tumors has been expanded significantly to include all phenotypes, a condition known as familial isolated pituitary adenomas (FIPA). In FIPA, tumors can present homogeneously (same phenotype) or heterogeneously (different tumor phenotypes) within the same family. Compared with sporadic pituitary adenomas, patients with FIPA have a younger age at diagnosis and have larger tumors. The clinical features of FIPA differ from those of MEN-1 in terms of a higher frequency of somatotropinomas and a lower frequency of prolactinomas. The recent discovery of the involvement of mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene in association with pituitary tumors has provided new information regarding potential mechanisms of tumorigenesis in FIPA patients. While very infrequent in sporadic pituitary tumors, approximately 15% of FIPA patients have AIP mutations, rising to half of patients with familial acromegaly. In this review, we detail the clinical features of FIPA and discuss tumor pathology and genetic findings in this increasingly recognized clinical condition. [less ▲]

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See detailNon-Rigid Object Tracker Based On a Robust Combination of Parametric Active Contour and Point Distribution Model
Olszewska, Joanna; Mathes, Tom; De Vleeschouwer, Christophe et al

in Proceedings of the SPIE Conference on Visual Communication and Image Processing (2007)

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See detailSobre armas y letras. El Quijote como intertexto en los relatos del Subcomandante Marcos
Vanden Berghe, Kristine ULg

in Boletin AFEHC (2007)

El Subcomandante Marcos multiplica las referencias a Don Quijote de la Mancha en sus diversas estrategias para construir la imagen del EZLN y de sus enemigos. Esta contribución se concentrará en aquellos ... [more ▼]

El Subcomandante Marcos multiplica las referencias a Don Quijote de la Mancha en sus diversas estrategias para construir la imagen del EZLN y de sus enemigos. Esta contribución se concentrará en aquellos aspectos de su discurso que tienen que ver con la construcción del narrador y de los personajes en la medida en que se inspiren en el texto de Cervantes y que se hayan publicado entre 1994 y 1999. Se trata principalmente de los relatos que Marcos ha escrito acerca del escarabajo parlante Durito y que, en 1999, han sido reunidos en el libro Don Durito de la Lacandona (Chiapas, CIACH). Para poder entender las implicaciones de esta intertextualidad con la obra de Cervantes, cabe recordar también algunos aspectos básicos del discurso del EZLN y la problemática de las distintas voces en las filas zapatistas. [less ▲]

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See detailDes images et des récits qui disent le changement, des questions, des impasses et des possibles
Stassart, Pierre M ULg; Lecomte, Nadége

in Regards croisés (2007)

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See detailNeonatal screening of hemoglobinopathies on dried blood
BOEMER, François ULg

Conference (2007)

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See detailOrganisation du pool genique de Vigna unguiculata (L.) Walp.: croisements entre les formes sauvages et cultivees du niebe.
Kouadio, D.; Echikh, Nadejda ULg; Toussaint, André ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 47-57

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See detailEtude d'impact de la MTR en Région wallonne
Delille, Nicolas ULg

Report (2007)

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See detailSequential Variational Inference for Distributed Multi-Sensor Tracking and Fusion
Du, Wei ULg; Piater, Justus ULg

in The 10th International Conference on Information Fusion (2007)

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See detailMulti-Camera People Tracking by Collaborative Particle Filters and Principal Axis-Based Integration
Du, Wei ULg; Piater, Justus ULg

in Asian Conference on Computer Vision (2007)

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See detailDiagnostic agronomique et agro-environnemental des successions culturales en Wallonie (Belgique).
Leteinturier, Béatrice; Tychon, Bernard ULg; Oger, Robert ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2007), 11(1), 27-38

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l ... [more ▼]

La succession culturale, reconnue comme une notion fondamentale assurant un équilibre tant agronomique au niveau parcellaire qu'agro-environnemental au niveau de l'agro-écosystème, est analysée à l'échelle des régions agricoles qui composent le territoire de la Wallonie (Belgique). L'étude vise à dresser un diagnostic des performances qualitatives des successions culturales, à travers l'analyse individuelle de plusieurs de leurs composantes explicatives telles la qualité des précédents culturaux sur les cultures suivantes, le temps de retour moyen des cultures, le nombre de cultures apparaissant au cours de la succession et enfin la durée des périodes interculturales. Ces quatre composantes sont analysées à l'échelle parcellaire, les résultats étant agrégés au niveau régional. L'étude porte à la fois sur une analyse spatiale basée sur une période de 7 années, ainsi que sur une analyse temporelle visant à observer une éventuelle évolution, région par région, au cours de deux périodes successives de même durée. L'état des lieux ainsi dressé révèle des différences spatiales en termes de pratiques liées aux successions culturales, par contre, une quasi-stabilité dans le temps des paramètres analysés découle des résultats obtenus. Par ailleurs, si ces résultats contribuent à enrichir un état des lieux de l'agriculture en Wallonie, ils peuvent en outre servir de valeurs de référence pour un suivi global de l'évolution des pratiques agricoles régionales. [less ▲]

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See detailIsaac Bashevis Singer, ou la littérature comme illustration d'une théorie du droit
Thirion, Nicolas ULg

in Liber amicorum Paul Martens. L'humanisme dans la résolution des conflits. Utopie ou réalité? (2007)

Illustration de la théorie de la pluralité des ordres juridiques de Santi Romano par une nouvelle d'Isaac Bashevis Singer tiré du recueil "Au tribunal de mon père"

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See detailp27Kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.
Nguyen, Laurent ULg; Besson, A.; Heng, J Ik-Tsen et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2007), 162(5-6), 310-4

The generation of glutamatergic neurons by stem and progenitor cells is a complex process involving the tight coordination of multiple cellular activities, including cell cycle exit, initiation of ... [more ▼]

The generation of glutamatergic neurons by stem and progenitor cells is a complex process involving the tight coordination of multiple cellular activities, including cell cycle exit, initiation of neuronal differentiation and cell migration. The mechanisms that integrate these different events into a coherent program are not well understood. Here we show that the cyclin-dependent kinase inhibitor p27Kip1 plays an important role in neurogenesis in the mouse cerebral cortex, by promoting the differentiation and radial migration of cortical projection neurons. Importantly, p27Kip1 promotes neuronal differentiation and neuronal migration via two distinct mechanisms, which are themselves independent of the cell cycle regulatory function of p27Kip1. p27Kip1 inactivation by gene targeting or RNA interference results in neuronal differentiation and radial migration defects, demonstrating that p27Kip1 regulates cell migration in vivo. The differentiation defect, but not the migration defect, is rescued by overexpression of the proneural gene Neurogenin 2. p27Kip1 acts by stabilizing Neurogenin 2 protein, an activity carried by the N-terminal half of the protein. The migration defect resulting from p27Kp1 inactivation is rescued by blocking RhoA signalling, an activity that resides in the c-terminal half of p27Kip1. Thus, p27Kip1 plays a key role in cortical development, acting as a modular protein that independently regulates and couples multiple cellular pathways contributing to neurogenesis. [less ▲]

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See detailSpontaneous coronary artery dissection in an antilles man with acute inferior myocardial infarction.
Pierre-Justin, Gilbert; Pierard, Luc ULg

in International journal of cardiology (2007), 118(2), 237-40

Spontaneous coronary artery dissection is a rare cause of myocardial infarction. It has been reported mainly in young women during or after pregnancy. The diagnosis is usually confirmed at autopsy. The ... [more ▼]

Spontaneous coronary artery dissection is a rare cause of myocardial infarction. It has been reported mainly in young women during or after pregnancy. The diagnosis is usually confirmed at autopsy. The management of these patients remains controversial. We report the case of a patient who presented spontaneous dissection and was with successfully treated by thrombolysis. Clinical outcome was good. [less ▲]

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See detailCarte hydrogéologique de Wallonie 1/25000. 65/7-8, Limerlé-Langler.
Bouezmarni, Mohamed ULg; Denne, Pierre; Debbaut, Vincent ULg

Cartographic material (2007)

Detailed reference viewed: 7 (1 ULg)