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See detailRmd9p controls the processing/stability of mitochondrial mRNAs and its overexpression compensates for a partial deficiency of oxa1p in Saccharomyces cerevisiae.
Nouet, Cécile ULg; Bourens, Myriam; Hlavacek, Otakar et al

in Genetics (2007), 175(3), 1105-15

Oxa1p is a key component of the general membrane insertion machinery of eukaryotic respiratory complex subunits encoded by the mitochondrial genome. In this study, we have generated a respiratory ... [more ▼]

Oxa1p is a key component of the general membrane insertion machinery of eukaryotic respiratory complex subunits encoded by the mitochondrial genome. In this study, we have generated a respiratory-deficient mutant, oxa1-E65G-F229S, that contains two substitutions in the predicted intermembrane space domain of Oxa1p. The respiratory deficiency due to this mutation is compensated for by overexpressing RMD9. We show that Rmd9p is an extrinsic membrane protein facing the matrix side of the mitochondrial inner membrane. Its deletion leads to a pleiotropic effect on respiratory complex biogenesis. The steady-state level of all the mitochondrial mRNAs encoding respiratory complex subunits is strongly reduced in the Deltarmd9 mutant, and there is a slight decrease in the accumulation of two RNAs encoding components of the small subunit of the mitochondrial ribosome. Overexpressing RMD9 leads to an increase in the steady-state level of mitochondrial RNAs, and we discuss how this increase could suppress the oxa1 mutations and compensate for the membrane insertion defect of the subunits encoded by these mRNAs. [less ▲]

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See detailFace Recognition Failures in Schizotypy
Laroi, Frank ULg; D'Argembeau, Arnaud ULg; Brédart, Serge ULg et al

in Cognitive Neuropsychiatry (2007), 12(6), 554-71

INTRODUCTION: Studies suggest an important role of disturbances of self in schizophrenia and in schizotypy. Based on findings from a previous study (Bredart & Young, 2004), we developed a questionnaire ... [more ▼]

INTRODUCTION: Studies suggest an important role of disturbances of self in schizophrenia and in schizotypy. Based on findings from a previous study (Bredart & Young, 2004), we developed a questionnaire assessing self-face recognition failures in everyday life (Self-Face Recognition Questionnaire; SFRQ) to investigate the relations between dimensions of schizotypy (cognitive-perceptual, interpersonal, disorganised) and self-face recognition disturbances. METHODS: A sample of nonclinical participants (n = 170) completed the SFRQ and the Schizotypal Personality Questionnaire. RESULTS: Factor analysis of SFRQ items revealed a clear three-factor structure consisting of: (1) self-face recognition difficulties, (2) unusual perception of own or other faces, and (3) other-face recognition difficulties. Correlational analyses between schizotypy dimensions and the SFRQ revealed that only the cognitive-perceptual and disorganised schizotypy dimensions correlated significantly with the SFRQ. By contrast, the interpersonal schizotypy dimension was not associated with the SFRQ. CONCLUSIONS: Findings provide further support that positive (cognitive-perceptual) and negative (interpersonal) schizotypy represent discrete neurobehavioural dimensions. The theoretical implications of these findings are discussed. [less ▲]

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See detail"Au-delà du principe de plaisir". Politique du désir et bataille de l'intelligence selon Bernard Stiegler
Cormann, Grégory ULg

in Matière & l'Esprit (La) (2007), 9

Ce bref article présente Mécréance et Discrédit. 3. L’esprit perdu du capitalisme de Bernard Stiegler. Cet ouvrage récent constitue une partie d’un programme philosophique original, commencé en 1994 avec ... [more ▼]

Ce bref article présente Mécréance et Discrédit. 3. L’esprit perdu du capitalisme de Bernard Stiegler. Cet ouvrage récent constitue une partie d’un programme philosophique original, commencé en 1994 avec La Technique et le Temps 1. Profondément inscrit au sein de la pensée française contemporaine, notamment phénoménologique et psychanalytique, il donne d’un même élan la possibilité de penser la situation politique et intellectuelle depuis 1968 sur la base de ce qui a longtemps constitué l’impensé de la philosophie, la technique – marquée aujourd’hui par un devenir technologique de vaste ampleur –, menace mais aussi support prothétique de toute institution humaine individuelle ou collective. Le diagnostic sévère d’un épuisement du désir et d’une perte générale de l’attention exige une clarification de ces deux concepts, en vue de leur repolitisation. Un souci particulier sera accordé à la question de l’éducation, en tant qu’elle est le cadre dans lequel chacun de nous est affronté, de façon privilégiée, à ce qui, en lui, est bête. [less ▲]

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See detailLinking flux network measurements to continental scale simulations: Ecosystem carbon dioxide exchange capacity under non-water-stressed conditions
Owen, Katherine; Tenhunen, John; Reichstein, Markus et al

in Global Change Biology (2007), 13

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See detailLe Gravettien du Nord-ouest de l'Europe
Otte, Marcel ULg; Noiret, Pierre ULg

in Paléo. Revue d'Archéologie préhistorique (2007), 19

Around 30 sites have yielded Gravettian assemblages in Belgium. Present fairly early (28,000 BP), the Gravettian appears in trios distinct facies. The earliest includes large pointed blades and tanged ... [more ▼]

Around 30 sites have yielded Gravettian assemblages in Belgium. Present fairly early (28,000 BP), the Gravettian appears in trios distinct facies. The earliest includes large pointed blades and tanged tools; the most recent is marked by microlithic backed elements (truncated elements, microgravettes). These facies likely correspond to regional groups, for which the first can also be found fairly easily in neighbouring regions (England, Wales and northern France). In Rhenania, some 15 sites correspond to two facies (with Font Robert points and with microgravettes), similar but not identical to the Belgian facies. [less ▲]

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See detailTechnical efficiency in airlines under regulated and deregulated environments
Barla, Philippe; Perelman, Sergio ULg

in Annals of Public and Cooperative Economics = Annales de l'Economie Publique, Sociale et Coopérative (2007), 60

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See detailNatural dualities for varieties generated by a set of subalgebras of a semi-primal algebra
Mathonet, Pierre ULg; Niederkorn, Philippe; Teheux, Bruno ULg

in Algebra and Discrete Mathematics (2007), (1), 67--85

The main contribution of this paper is the construction of a strong duality for the varieties generated by a set of subalgebras of a semi-primal algebra. We also obtain an axiomatization of the objects of ... [more ▼]

The main contribution of this paper is the construction of a strong duality for the varieties generated by a set of subalgebras of a semi-primal algebra. We also obtain an axiomatization of the objects of the dual category and develop some algebraic consequences (description of the dual of the finite structures and algebras, construction of finitely generated free algebras,. . . ). Eventually, we illustrate this work for the finitely generated varieties of MV-algebras. [less ▲]

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See detailElectrical transport and magnetic properties of Mn3O4-La0.7Ca0.3MnO3 ceramic composites prepared by a one-step spray-drying technique
Vertruyen, Bénédicte ULg; Fagnard, Jean-François ULg; Vanderbemden, Philippe ULg et al

in Journal of the European Ceramic Society (2007), 27(13-15), 3923-3926

La0.7Ca0.3MnO3/Mn3O4 composites can be synthesized in one step by thermal treatment of a spray-dried precursor, instead of mixing pre-synthesized powders. Another advantage of this composite system is ... [more ▼]

La0.7Ca0.3MnO3/Mn3O4 composites can be synthesized in one step by thermal treatment of a spray-dried precursor, instead of mixing pre-synthesized powders. Another advantage of this composite system is that a long sintering step can be used without leading to significant modification of the manganite composition. The percolation threshold is reached at ~ 20 vol% of manganite phase. The 77 K low field magnetoresistance is enhanced to ~ 11 % at 0.15 T when the composition is close to the percolation threshold. (c) 2007 Elsevier Ltd. All rights reserved. [less ▲]

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See detailCompléments et exercices d'application du droit social
Clesse, Jacques ULg

Learning material (2007)

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See detailEffects of non-genetic and crossbreeding factors on daily milk yield of Ayrshire x (Sahiwal x Ankole) cows in Mahwa station (Burundi)
Hatungumukama, G.; Sidikou, D. L.; Leroy, Pascal ULg et al

in Livestock Science (2007), 110(1-2), 111-117

The study was carried out at the Mahwa station located in Bututsi natural region in South of Burundi at 1850 m of altitude. The objective of the study was to assess the effects of days in milk, cow's ... [more ▼]

The study was carried out at the Mahwa station located in Bututsi natural region in South of Burundi at 1850 m of altitude. The objective of the study was to assess the effects of days in milk, cow's calving age, type of crossbreeding, year and month of lactation, parity on daily milk yield of crossbreds Ayrshire (AY) x Sahiwal (S) x Ankole (A) cows. Milk yields were obtained from 9 cows (S) that have been both milked and suckled during the entire lactation, on 8 cows (M) only milked during the entire lactation and on 150 cows (SM) suckled before and milked after weaning. Data were analyzed using the procedure GLM in SAS for S,M, and SM cows separately. All factors affected significantly daily milk yields (P < 0.001). Least-squares means (LSM) for daily milk yields were highest at the 8th (7.16 +/- 0.07 1), 8th (7.63 +/- 0.35 1), and 7th (7.34 +/- 0.39 1) day in milk for SM, S and M lactations, respectively. The Wood model was able to detect 2 main groups of curve shape: standard for SM and S cows and atypical decreasing for M cows. An important decrease in milk production was observed around the 120th day in SM cows corresponding to the weaning period. Crossbreeding improved milk production and highest yields were observed with 50% to 75% of Ayrshire inheritance (LSM = 5 +/- 0.05 to 5.51 +/- 0.02 1/day). A significant increase was observed from 1977 to 1992 due to the improvement of genetic and management techniques. During this period, LSM raised from 1.26 +/- 0.11 1 to 4.74 +/- 0.03 1 per day for SM cows. Unfortunately, the 1993 civilian war destabilized the managerial techniques and consequently, the milk production decreased in Mahwa station, In all cows, milk production was significantly higher from December to May (LSM - 3.96 +/- 0.03 1/day) during the rainy season than in September (LSM = 3.12 +/- 0.03 1/day) at the end of the dry season. (C) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailAntimony vibrations in skutterudites probed by Sb-121 nuclear inelastic scattering
Wille, H *-C; Hermann, Raphaël ULg; Sergueev, I. et al

in Physical Review. B, Condensed Matter and Materials Physics (2007), 76(14),

The specific lattice dynamic properties of antimony in the unfilled CoSb3 and filled EuFe4Sb12 skutterudites have been determined by nuclear inelastic scattering at the Sb-121 nuclear resonance energy of ... [more ▼]

The specific lattice dynamic properties of antimony in the unfilled CoSb3 and filled EuFe4Sb12 skutterudites have been determined by nuclear inelastic scattering at the Sb-121 nuclear resonance energy of 37.1298(2) keV with a 4.5 meV high-resolution backscattering sapphire monochromator. The Sb partial vibrational density of states (DOS) shows a maximum centered at 17 and 16 meV in CoSb3 and EuFe4Sb12, respectively. The difference between the Sb DOSs of CoSb3 and EuFe4Sb12 reveals that upon filling there is a transfer of 10% of the vibrational states toward lower energy. Further, a likely indication of the coupling between the guest and the host lattice in rattler systems is observed, a coupling that is required to reduce the lattice thermal conductivity. [less ▲]

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See detailEffects of cyanamide and acetaldehyde accumulation on the locomotor stimulant and sedative effects of ethanol in mice
Tambour, Sophie ULg; Closon, Catherine; Tirelli, Ezio ULg et al

in Behavioural Pharmacology (2007), 18(8), 777-784

Ethanol administration induces both locomotor stimulant and sedative effects depending upon blood ethanol concentrations. Recent studies in rats and mice suggest that acetaldehyde, the first product of ... [more ▼]

Ethanol administration induces both locomotor stimulant and sedative effects depending upon blood ethanol concentrations. Recent studies in rats and mice suggest that acetaldehyde, the first product of ethanol metabolism, might be involved in the expression of both the stimulant and the sedative effects of ethanol. A number of studies have used the drug cyanamide in an attempt to clarify the role of acetaldehyde in the behavioral effects of ethanol. The results of such studies are, however, difficult to interpret because cyanamide is an inhibitor of the enzymes catalase and aldehyde dehydrogenase, two enzymes with opposite effects on brain acetaldehyde concentrations. This study was aimed at clarifying the effects of cyanamide on ethanol-induced locomotor stimulant and sedative effects in Swiss mice. The locomotor stimulant effects of ethanol were measured in standard activity boxes, whereas the sedative effects of ethanol were quantified using the loss of righting reflex procedure. Cyanamide prevented the locomotor stimulant effects of 2 g/kg ethanol, although this was mainly due to a potentiation of the inhibitory effects of ethanol as evidenced by a prolongation of ethanol-induced loss of righting reflex. Additionally, 4-methylpyrazole, an inhibitor of the enzyme alcohol dehydrogenase, prevented these effects of cyanamide. It is concluded that in vivo the effects of cyanamide are predominantly due to the inhibition of the enzyme aldehyde dehydrogenase, rather than to its effects on catalase. [less ▲]

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See detailLa qualification juridique de la relation de travail
Clesse, Jacques ULg

in Questions de droit social (2007)

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See detailRelevance of nitric oxide for myocardial remodeling.
MASSION, Paul ULg; Balligand, Jean-Luc

in Current Heart Failure Reports (2007), 4(1), 18-25

Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to maladaptive remodeling leading to heart failure. In rodent models of pressure overload or myocardial infarction, the ... [more ▼]

Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to maladaptive remodeling leading to heart failure. In rodent models of pressure overload or myocardial infarction, the three NO synthase (NOS) isoforms were shown to play a neutral, protective, or even adverse role in myocardial remodeling, depending on the quantity of NO produced, the location of each NOS and their regulators, the prevailing oxidant stress and resultant NO/oxidant balance, as well as NOS coupling/dimerization. Beside neuronal NOS and--in specific conditions--inducible NOS isoforms, endothelial NOS (eNOS) exerts cardioprotective effects on pressure-overload, ischemia/reperfusion, and myocardial infarction-induced myocardial remodeling, provided the enzyme remains in a coupled state. Besides its effects on excitation-contraction coupling in response to stretch, eNOS acts as an "endogenous beta-blocker" by restoring the sympathovagal balance, opposing excessive hypertrophy as well as promoting vasodilatation and neoangiogenesis, thereby contributing to tissue repair. As eNOS was also shown to mediate the beneficial effects of cardiovascular drugs commonly used in patients with heart failure, strategies to increase its expression and/or coupled catalytic activity in the myocardium offer new therapeutic avenues for the treatment of this disease. [less ▲]

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See detailSensitivity analysis of the peak outflow induced by the breaching of embankment dams
Dewals, Benjamin ULg; Archambeau, Pierre ULg; Erpicum, Sébastien ULg et al

in Rutschmann, Peter (Ed.) Berichte des Lehrstuhls und der Versuchanstalt für Wasserbau und Wasserwirtschaft (2007)

Accurately predicting the flow induced by the collapse of embankment dams remains challenging, as a consequence of the level of uncertainty affecting the prediction of breach width and formation time ... [more ▼]

Accurately predicting the flow induced by the collapse of embankment dams remains challenging, as a consequence of the level of uncertainty affecting the prediction of breach width and formation time. Moreover, very few systematic analyses are available today concerning the sensitivity of the flow with respect to those uncertainties. The present theoretical analysis quantifies the influence of variations in the breach parameters on the peak outflow. [less ▲]

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See detailThe effect of high CO2 during the first half of incubation on embryonic development after storage
Witters, A.; Debonne, M.; Everaert, Nadia ULg et al

Poster (2007)

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See detailTestostérone et troubles de l'humeur
Scantamburlo, Gabrielle ULg

Conference (2007)

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See detailPour le multilinguisme : Exploiter à l'école la diversité des contextes européens : Résultats d'une étude internationale
Androulakis, G.; Beckmann, C.; Blondin, Christiane ULg et al

Book published by Editions de l'Université de Liège (2007)

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See detailOpera latina : le nouveau site Internet du LASLA
Denooz, Joseph ULg

in Citti, Francesco; dell Vecchio, Tommaso (Eds.) Proceedings of the Colloquium (2007)

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