References of "2007"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailA recombinant koi herpesvirus (KHV) or Cyprinid herpesvirus 3 (CyHV-3) and a vaccine for the prevention of a desease caused by KHV/CyHV-3 in Cyprinus carpio or Cyprinus carpio koi
Costes, Bérénice ULg; Lieffrig, F.; Vanderplasschen, Alain ULg

in EP 07115093.2 (2007)

The present invention refers to a recombinant koi herpesvirus (KHV) or Cyprinid herpesvirus 3 (CyHV-3), which is immunogenic in fish, preferably in carps, more preferably in Cyprinus carpio, and to a ... [more ▼]

The present invention refers to a recombinant koi herpesvirus (KHV) or Cyprinid herpesvirus 3 (CyHV-3), which is immunogenic in fish, preferably in carps, more preferably in Cyprinus carpio, and to a vaccine for preventive and/or therapeutic treatment of a disease caused by koi herpesvirus (KHV) or CyHV-3. The 5 recombinant herpesvirus is used to confer immunity on fish, preferably on carps, more preferably on Cyprinus carpio, against a disease caused by koi herpesvirus (KHV) or Cyprinid herpesvirus 3 (CyHV-3). [less ▲]

Detailed reference viewed: 134 (6 ULg)
Full Text
See detailPotentialités antipaludiques des alcaloïdes indoliques
Frederich, Michel ULg; Philippe, Geneviève ULg; Tits, Monique ULg et al

in Actualités de Chimie Thérapeutique (2007), 33

This paper will be mainly illustrated with references to selected antiplasmodial compounds:- indole alkaloid analogues of emetine isolated from Strychnos usambarensis and Pogonopus tubulosus-other ... [more ▼]

This paper will be mainly illustrated with references to selected antiplasmodial compounds:- indole alkaloid analogues of emetine isolated from Strychnos usambarensis and Pogonopus tubulosus-other bisindole alkaloids isolated from Loganiacea and Apocynaceae -indoloquinolines (cryptolepine and analogues) -indolo quinazoline-6,12-diones and derivatives from Strobilanthes and other sources -aminopolycyclic beta-carbolines ( manzamines) !solated from Indo-Pacific sponges. The paper will be finally also focused on the design of chemosensitizers that are capable of reversing in vitro chloroquine resistance( case of some mono-indole alkaloids). [less ▲]

Detailed reference viewed: 48 (6 ULg)
See detailBlanc-Bleu Mixte: Spécificités des Elevages
Bastin, Catherine ULg; Mayeres, Patrick

Article for general public (2007)

Detailed reference viewed: 68 (22 ULg)
Full Text
Peer Reviewed
See detailGlucosamine and chondroitin sulfate as therapeutic agents for knee and hip Osteoarthritis
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Drugs & Aging (2007), 24(7), 573-580

Osteoarthritis (OA), the most common form of arthritis, is a public health problem throughout the world. Several entities have been carefully investigated for the symptomatic and structural management of ... [more ▼]

Osteoarthritis (OA), the most common form of arthritis, is a public health problem throughout the world. Several entities have been carefully investigated for the symptomatic and structural management of OA. This review evaluates published studies of the effect of glucosamine salts and chondroitin sulfate preparations on the progression of knee or hip OA. Despite multiple double-blind, controlled clinical trials of the use of glucosamine and chondroitin sulfate in OA, controversy regarding the efficacy of these agents with respect to symptomatic improvement remains. Several potential confounders, including placebo response, use of prescription medicines versus over-the-counter pills or food supplements, or use of glucosamine sulfate versus glucosamine hydrochloride, may have relevance when attempting to interpret the seemingly contradictory results of different clinical trials. The National Institutes of Health-sponsored GAIT (Glucosamine/chondroitin Arthritis Intervention Trial) compared placebo, glucosamine hydrochloride, chondroitin sulfate, a combination of glucosamine and chondroitin sulfate and celecoxib in a parallel, blinded 6-month multicentre study of patients with knee OA. This trial showed that glucosamine hydrochloride and chondroitin sulfate alone or in combination did not reduce pain effectively in the overall group of patients with OA of the knee. However, exploratory analyses suggest that the combination of glucosamine hydrochloride and chondroitin sulfate may be effective in the subgroup of patients with moderate-to-severe knee pain. For decades, the traditional pharmacological management of OA has been mainly symptomatic. However, in recent years, several randomised controlled studies have assessed the structure-modifying effect of glucosamine sulfate and chondroitin sulfate using plain radiography to measure joint space narrowing over years. There is some evidence to suggest a structure-modifying effect of glucosamine sulfate and chondroitin sulfate. On the basis of the results of recent randomised controlled trials and meta-analyses, we can conclude that glucosamine sulfate (but not glucosamine hydrochloride) and chondroitin sulfate have small-to-moderate symptomatic efficacy in OA, although this is still debated. With respect to the structure-modifying effect, there is compelling evidence that glucosamine sulfate and chondroitin sulfate may interfere with progression of OA. [less ▲]

Detailed reference viewed: 211 (12 ULg)
Full Text
Peer Reviewed
See detailStress concentration minimization of 2D filets using X-FEM and level set description
Van Miegroet, Laurent ULg; Duysinx, Pierre ULg

in Structural and Multidisciplinary Optimization (2007), 33(4-5), 425-438

This paper presents and applies a novel shape optimization approach based on the level set description of the geometry and the extended finite element method (X-FEM). The method benefits from the fixed ... [more ▼]

This paper presents and applies a novel shape optimization approach based on the level set description of the geometry and the extended finite element method (X-FEM). The method benefits from the fixed mesh work using X-FEM and from the curves smoothness of the level set description. Design variables are shape parameters of basic geometric features that are described with a level set representation. The number of design variables of this formulation remains small, whereas global (i.e. compliance) and local constraints (i.e. stresses) can be considered. To illustrate the capability of the method to handle stress constraints, numerical applications revisit the minimization of stress concentration in a 2D filet in tension, which has been previously studied in Pedersen (2003). Our results illustrate the great interest of using X-FEM and level set description together. A special attention is also paid to stress computation and accuracy with the X-FEM. [less ▲]

Detailed reference viewed: 99 (18 ULg)
Full Text
Peer Reviewed
See detailEpithelial-mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions.
Ullmann, U.; In'T Veld, P.; Gilles, Christine ULg et al

in Molecular Human Reproduction (2007), 13(1), 21-32

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early ... [more ▼]

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early differentiation process. Long-term feeder-free hESC cultures using matrigel and conditioned medium from mouse and from human origin revealed that the appearance of mesenchymal-like cells was similar regardless of the conditioned medium used. Standard characterization confirmed the preservation of hESC properties, but the feeder-free cultures could not be maintained longer than 37 passages. The early differentiation process was characterized in the short term after switching hESCs cultured on feeders to feeder-free conditions. Transmission electron microscopy showed an epithelium-like structure inside the hESC colonies, whereas the peripheral cells revealed the acquisition of a rather mesenchymal-like phenotype. Immunochemistry analysis showed that cells at the periphery of the colonies had a negative E-cadherin expression and a positive Vimentin expression, suggesting an epithelial–mesenchymal transition (EMT). Nuclear staining of ß-catenin, positive N-cadherin and negative Connexin 43 expression were also found in the mesenchymal-like cell population. After RT–PCR analysis, Slug and Snail, both EMT-related transcription factors, were detected as up-regulated in the mesenchymal-like cell population. Taken together, our data suggest that culturing hESCs in feeder-free conditions enhances an early differentiation process identified as an EMT. [less ▲]

Detailed reference viewed: 33 (2 ULg)
Full Text
See detailGénération automatique d'une base de données de silhouettes humaines au moyen d'un avatar humain tridimensionnel
Pierard, Sébastien ULg

Master's dissertation (2007)

Pour la conception de systèmes de vidéo-surveillance, il est avantageux d’avoir un système de détection automatique d’êtres humains. Certains de ces systèmes sont basés sur la reconnaissance de la forme ... [more ▼]

Pour la conception de systèmes de vidéo-surveillance, il est avantageux d’avoir un système de détection automatique d’êtres humains. Certains de ces systèmes sont basés sur la reconnaissance de la forme de silhouettes humaines. L’utilisation de méthodes d'apprentissage pour la reconnaissance nécessite une base de données de silhouettes humaines, dont il est intéressant d’automatiser la génération. Dans ce travail, nous utilisons un avatar humain tridimensionnel, celui du projet open-source MakeHuman, afin de générer automatiquement la base de données. Le choix des configurations (positions, orientations et poses) à donner à l’avatar pour obtenir une base de données adéquate est central. Dans un premier temps, nous tentons une étude de l’impact de modifications dans le mode tridimensionnel sur la silhouette. Cet impact est quantifié par la distance de Hausdorff. Parmi les modifications envisagées se trouvent le déplacement, la rotation et le changement de pose de l’avatar. Nous espérions déterminer, à partir de ces impacts, les pas par lesquels doivent varier les différents paramètres. Les configurations que doit prendre l’avatar, pour obtenir une base de données suffisamment riche sans être trop volumineuse, seront obtenues en prenant toutes les combinaisons des valeurs des différents paramètres. Le nombre de configurations est exponentiel en le nombre de degrés de liberté, ce qui rend l’approche inutilisable en pratique, même si nous sommes indifférents à la translation et à la mise à l’échelle des silhouettes. Dans un deuxième temps, nous avons opté pour une approche radicalement différente. Cette fois, nous n’espaçons plus les silhouettes, mais les poses. La position de l’avatar est fixée et il ne peut tourner qu’autour de l’axe vertical. Les poses sont choisies en effectuant des tirages aléatoires des différents paramètres. Cette approche aléatoire du problème a mené à l’élaboration d’un nouveau logiciel, Silhouette. Il est écrit en Java et une interface écrite en C lui permet, grâce à Java Native Interface d’exploiter efficacement le moteur de pose de MakeHuman. Parmi les fonctionnalités de Silhouette, notons la possibilité de restreindre les poses à un ensemble voulu, de ne générer que des silhouettes correspondant à des poses licites et d’annoter les silhouettes. Grâce au logiciel mis en place, nous avons été en mesure de générer diverses bases de données. Nous avons étudié l'impact de l'utilisation de celles-ci sur les performances d'un système de détection de personnes existant. Nous obtenons des résultats encourageants, 73% des silhouettes humaines étant correctement détectées. Un raffinement et un paramétrage soigneux de la méthode devraient mener à des résultats excellents. [less ▲]

Detailed reference viewed: 66 (6 ULg)
See detailBonne gouvernance et marchés publics
Durviaux, Ann-Lawrence ULg

Conference given outside the academic context (2007)

Detailed reference viewed: 156 (6 ULg)
Peer Reviewed
See detailEffects of attention on emotional face processing in depression : a functional MRI study
Desseilles, Martin; Maquet, Pierre ULg; Dang Vu, Thien Thanh et al

Poster (2007)

Detailed reference viewed: 13 (2 ULg)
See detailRobust computation of stress intensity factors within the eXtended Finite Element Method
Chevaugeon, N.; Moës, Nicolas; Minnebo, Hans et al

Scientific conference (2007)

Detailed reference viewed: 20 (3 ULg)
Full Text
Peer Reviewed
See detailStudy of axes rotation during simple shear tests on aluminium sheets
Duchene, Laurent ULg; Diouf, B.; Lelotte, T. et al

in César de Sa, J. M. A.; Santos, Abel D. (Eds.) Proceedings of the 9th International Conference NUMIFORM 2007 (2007)

In order to model accurately the anisotropic material behavior during finite element simulations, a precise description of the material yield locus is required. Beside the shape (linked to the material ... [more ▼]

In order to model accurately the anisotropic material behavior during finite element simulations, a precise description of the material yield locus is required. Beside the shape (linked to the material model used), the size (related to the isotropic hardening) and the position (kinematic hardening) of the yield locus, its orientation is of particular interest when large rotations of the material are encountered during the simulations. This paper proposes three distinct methods for the determination of the material yield locus rotation: a method based on the Constant Symmetric Local Velocity Gradient (CSLVG), a corotational method and a method based on the Mandel spin. These methods are compared during simple shear tests of an aluminum sheet. [less ▲]

Detailed reference viewed: 20 (3 ULg)
Full Text
See detailMitoc-Malu Galben: étude de l'industrie lithique
Otte, Marcel ULg; Noiret, Pierre ULg; Chirica, Vasile et al

in Otte, Marcel; Chirica, Vasile; Haesaerts, Paul (Eds.) L'Aurignacien et le Gravettien de Mitoc-Malu Galben (Moldavie roumaine) (2007)

Detailed reference viewed: 69 (5 ULg)
Full Text
See detailMitoc-Malu Galben: industrie osseuse et témoins esthétiques
Chirica, Vasile; Noiret, Pierre ULg

in Otte, Marcel; Chirica, Vasile; Haesaerts, Paul (Eds.) L'Aurignacien et le Gravettien de Mitoc-Malu Galben (Moldavie roumaine) (2007)

Detailed reference viewed: 46 (7 ULg)
Full Text
Peer Reviewed
See detailScreening for colorectal cancer in 2006
Piront, Patricia ULg; Louis, Edouard ULg; Belaiche, Jacques ULg et al

in Acta Endoscopica (2007), 37(3), 305-313

Colorectal cancer is the second leading cause of death in Northern countries and needs a national screening program to reduce mortality and improve quality of life. Screening has to be cost-effective and ... [more ▼]

Colorectal cancer is the second leading cause of death in Northern countries and needs a national screening program to reduce mortality and improve quality of life. Screening has to be cost-effective and acceptable for patients. Many screening tools, invasive or not, are existing and often debated: FOBT, sigmoidoscopy and complete colonoscopy. New tools are in development and have to be evaluated in current practice: virtual colonoscopy, new endoscopic technologies, DNA on faeces or proteomics with markers in serum. [less ▲]

Detailed reference viewed: 25 (2 ULg)
Full Text
See detailConclusion
Otte, Marcel ULg; Chirica, Vasile; Haesaerts, Paul et al

in Otte, Marcel; Chirica, Vasile; Haesaerts, Paul (Eds.) L'Aurignacien et le Gravettien de Mitoc-Malu Galben (Moldavie roumaine) (2007)

Detailed reference viewed: 21 (2 ULg)
Full Text
Peer Reviewed
See detailUltrastructural alterations of elastic fibers and other dermal components in ehlers-danlos syndrome of the hypermobile type.
Hermanns-Lê, Trinh ULg; Pierard, Gérald ULg

in American Journal of Dermatopathology (2007), 29(4), 370-3

Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders with varied molecular abnormalities. Some morphologic alterations are described in collagen and elastic fibers. We ... [more ▼]

Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders with varied molecular abnormalities. Some morphologic alterations are described in collagen and elastic fibers. We report on previously undescribed ultrastructural changes in the elastic fibers found in the skin of 22 of 29 patients suffering from the hypermobile type of EDS. They existed in variable combinations of a fragmented appearance with frayed contours, internal microcavities, some elastotic-like changes, and discrete calcified foci. The collagen fibrils and their bundles were also altered with morphologic aspects reminiscent of those found in the classical type of EDS. Large globules of hyaluronic acid were also dispersed in the amorphous matrix. [less ▲]

Detailed reference viewed: 42 (3 ULg)
See detailTroubles bipolaires: de la psychopathologie au traitement
Scantamburlo, Gabrielle ULg

Learning material (2007)

Detailed reference viewed: 52 (13 ULg)