References of "2007"
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See detailLes ondes gravitationnelles
De Rop, Yves ULg

in Revue des Questions Scientifiques (2007), 178(1), 113-138

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See detailBlanc-Bleu Mixte: Spécificités des Elevages
Bastin, Catherine ULg; Mayeres, Patrick

Article for general public (2007)

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See detailNouveautés dans la prise en charge des anomalies du bilan phosphocalcique chez le patient dialysé
Delanaye, Pierre ULg; Van Overmeire, Lionel ULg; Dubois, Bernard ULg et al

in Revue Médicale de Liège (2007), 62(5-6, May-Jun), 360-5

Disorders of the phosphocalcic metabolism are frequent in dialysis patients. Such disorders are difficult to treat and have negative impact on bone health, but also on cardiovascular mortality ... [more ▼]

Disorders of the phosphocalcic metabolism are frequent in dialysis patients. Such disorders are difficult to treat and have negative impact on bone health, but also on cardiovascular mortality. Hyperphosphoremia is a strong predictor of cardiovascular mortality. New phosphate binders are now available in Belgium. A new molecule acting on the calcium receptor of the parathyroid glands is able to control secondary and tertiary hyperparathyroidism in dialysis patients. These new therapies, specific for dialysis patients, will be reviewed in this article. [less ▲]

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See detailDuden - Das Synonymwörterbuch
Beil, Christine; Knörr, Evelyn; Münzberg, Franziska ULg et al

Book published by Dudenverlag (2007)

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See detailSedimentology and magnetic susceptibility of the Couvin Formation (Eifelian, South Western Belgium): Carbonate platform initiation in a hostile world
Mabille, Cédric ULg; Boulvain, Frédéric ULg

in Geologica Belgica (2007), 10(1-2), 47-67

The Eifelian of Belgium is mainly characterised by a mixed siliciclastic-carbonate sedimentation on a ramp profile. In this context, the Couvin Formation is the more important and remarkable exception. It ... [more ▼]

The Eifelian of Belgium is mainly characterised by a mixed siliciclastic-carbonate sedimentation on a ramp profile. In this context, the Couvin Formation is the more important and remarkable exception. It represents a carbonate platform initiation in a hostile environment. This work is mainly based on the stratotype, corresponding to two stratigraphic sections located in Couvin, along the southern border of the Dinant Synclinorium. These sections are the Eau Noire and Falaise de l'Abime sections. Unfortunately, they are discontinuous. To allow a better understanding of the sedimentary dynamics, the data are complemented by a shorter but continuous section located in Villers-la-Tour (3.5 km West of Chimay). Petrographic study leads to the definition of 14 microfacies which are integrated in a palaeogeographical model. It corresponds to a platform setting where the reef complex is mainly constituted by an accumulation of crinoids, stromatoporoids and tabulate corals. The microfacies evolution is interpreted in terms of bathymetrical variations. It shows a general shallowing-upward trend encompassing the vertical succession of fore-reef settings, reef development, back-reef and then lagoon environment. This interpretation is supported by trends in mean magnetic susceptibility data, providing a better understanding of the sedimentary dynamics. Moreover, these data show positive correlation with concentrations of detritic minerals, but an inverse relationship with well washed skeletal limestones. The comparison of the three studied sections leads to considerations concerning the lateral variability in the Couvin Formation indicating more agitated conditions in the Abime Member in Villers-le-Tour section. [less ▲]

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See detailLangues classiques et informatique : les premiers travaux
Denooz, Joseph ULg

in Denooz, Joseph; Citti, Francesco; del Vecchio, Tommaso (Eds.) Proceedings of the Colloquium (Bologna, 12 juin 2003) (2007)

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See detailTroubles bipolaires: de la psychopathologie au traitement
Scantamburlo, Gabrielle ULg

Learning material (2007)

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See detailEpithelial-mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions.
Ullmann, U.; In'T Veld, P.; Gilles, Christine ULg et al

in Molecular Human Reproduction (2007), 13(1), 21-32

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early ... [more ▼]

Feeder-free human embryonic stem cell (hESC) culture is associated with the presence of mesenchymal-like cells appearing at the periphery of the colonies. The aim of this study was to identify this early differentiation process. Long-term feeder-free hESC cultures using matrigel and conditioned medium from mouse and from human origin revealed that the appearance of mesenchymal-like cells was similar regardless of the conditioned medium used. Standard characterization confirmed the preservation of hESC properties, but the feeder-free cultures could not be maintained longer than 37 passages. The early differentiation process was characterized in the short term after switching hESCs cultured on feeders to feeder-free conditions. Transmission electron microscopy showed an epithelium-like structure inside the hESC colonies, whereas the peripheral cells revealed the acquisition of a rather mesenchymal-like phenotype. Immunochemistry analysis showed that cells at the periphery of the colonies had a negative E-cadherin expression and a positive Vimentin expression, suggesting an epithelial–mesenchymal transition (EMT). Nuclear staining of ß-catenin, positive N-cadherin and negative Connexin 43 expression were also found in the mesenchymal-like cell population. After RT–PCR analysis, Slug and Snail, both EMT-related transcription factors, were detected as up-regulated in the mesenchymal-like cell population. Taken together, our data suggest that culturing hESCs in feeder-free conditions enhances an early differentiation process identified as an EMT. [less ▲]

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See detailMaladie de Darier zostériforme et infection herpétique.
Blaise, Géraldine; Franchimont, Claudine ULg; Quatresooz, Pascale ULg et al

in Dermatologie Actualité (2007), 102

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See detailDes pratiques agricoles aux reliquats en azote nitrique des sols en région wallonne.
Borgers, N.; Vandenberghe, Christophe ULg; Marcoen, Jean Marie ULg

Report (2007)

Collaboration scientifique entre l’Unité d’Hydrologie et d’Hydraulique agricole et le Groupe de Recherche en Environnement et Ressources Azotées dans le cadre de l’Evaluation des mesures prises pour ... [more ▼]

Collaboration scientifique entre l’Unité d’Hydrologie et d’Hydraulique agricole et le Groupe de Recherche en Environnement et Ressources Azotées dans le cadre de l’Evaluation des mesures prises pour réduire les incidences de la pollution diffuse d’origine agricole et domestique sur la qualité des masses d’eau de surface et souterraines de la région wallonne à l’aide du modèle EPICgrid-PIRENE (Convention RW-SPGE). [less ▲]

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See detailEffects of age and Ascaris suum aerosol exposure on the pro- and antigelatinolytic activity in serum and airways of cats
Leemans, Jérôme ULg; Kirschvink, N.; Billen, Frédéric et al

in Proceedings : 17th Congress of the European College of Veterinary Internal Medicine – Companion Animals, Budapest (2007)

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See detailDrug-drug and food-drug pharmacokinetic interactions with new insulinotropic agents repaglinide and nateglinide.
Scheen, André ULg

in Clinical Pharmacokinetics (2007), 46(2), 93-108

This review describes the current knowledge on drug-drug and food-drug interactions with repaglinide and nateglinide. These two meglitinide derivatives, commonly called glinides, have been developed for ... [more ▼]

This review describes the current knowledge on drug-drug and food-drug interactions with repaglinide and nateglinide. These two meglitinide derivatives, commonly called glinides, have been developed for improving insulin secretion of patients with type 2 diabetes mellitus. They are increasingly used either in monotherapy or in combination with other oral antihyperglycaemic agents for the treatment of type 2 diabetes. Compared with sulfonylureas, glinides have been shown to (i) provide a better control of postprandial hyperglycaemia, (ii) overcome some adverse effects, such as hypoglycaemia, and (iii) have a more favourable safety profile, especially in patients with renal failure.The meal-related timing of administration of glinides and the potential influence of food and meal composition on their bioavailability may be important. In addition, some food components (e.g. grapefruit juice) may cause pharmacokinetic interactions. Because glinides are metabolised via cytochrome P450 (CYP) 3A4 isoenzyme, they are indeed exposed to pharmacokinetic interactions. In addition to CYP3A4, repaglinide is metabolised via CYP2C8, while nateglinide metabolism also involves CYP2C9. Furthermore, both compounds and their metabolites may undergo specialised transport/uptake in the intestine, another source of pharmacokinetic interactions. Clinically relevant drug-drug interactions are those that occur when glinides are administered together with other glucose-lowering agents or compounds widely coadministered to diabetic patients (e.g. lipid-lowering agents), with drugs that are known to induce (risk of lower glinide plasma levels and thus of deterioration of glucose control) or inhibit (risk of higher glinide plasma levels leading to hypoglycaemia) CYP isoenzymes concerned in their metabolism, or with drugs that have a narrow efficacy : toxicity ratio.Pharmacokinetic interactions reported in the literature appear to be more frequent and more important with repaglinide than with nateglinide. Rifampicin (rifampin) reduced repaglinide area under the plasma concentration-time curve (AUC) by 32-85% while it reduced nateglinide AUC by almost 25%. Reported increases in AUCs with coadministration of drugs inhibiting CYP isoenzymes never exceeded 80% for repaglinide (except with ciclosporin and with gemfibrozil) and 50% for nateglinide. Ciclosporin more than doubled repaglinide AUC (+144%), a finding that should raise caution when using these two drugs in combination. The most impressive pharmacokinetic interaction was reported with combined administration of gemfibrozil (a strong CYP2C8 inhibitor) and repaglinide (8-fold increase in repaglinide AUC). Although no studies have been performed in patients with type 2 diabetes, the latter combination should be avoided in clinical practice. [less ▲]

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See detailThe expression of Clostridium perfringens consensus beta2 toxin is associated with bovine enterotoxaemia syndrome
Lebrun, Maud; Filée, Patrice ULg; Mousset, Bénédicte ULg et al

in Veterinary Microbiology (2007), 120(1-2), 151-157

Clostridium perfringens has been implicated in a broad array of enteric infections including the fatal haemorrhagic enteritis/enterotoxaemia syndrome in cattle. The beta2 toxin (CPB2), encoded by cpb2, is ... [more ▼]

Clostridium perfringens has been implicated in a broad array of enteric infections including the fatal haemorrhagic enteritis/enterotoxaemia syndrome in cattle. The beta2 toxin (CPB2), encoded by cpb2, is suspected to be implicated in this syndrome. However, among C. perfringens isolates from cattle suspected of clostridial disease, an atypical allele was recently found to predominate at the cpb2 locus and atypical corresponding CPB2 proteins were shown to be poorly expressed, thus arguing against a biologically significant role of the beta2 toxin in clostridial diseases in cattle. This study compared genotype and phenotype of the beta2 toxin between C. perfringens isolates from a group of healthy calves (n = 14, 87 isolates) and from a group of enterotoxaemic calves (n = 8,41 isolates). PCR results revealed the exclusive presence of the typical "consensus" cpb2 in the enterotoxaernic group. Western blot analysis demonstrated that the typical variant of CPB2 was often expressed in isolates from enterotoxaemic calves (43.9%) and infrequently in isolates from healthy cattle (6.9%). These data suggest that the typical variant of the CPB2 toxin may play a role in the pathogenesis of cattle enterotoxaemia. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailThe stifle and tarsus
Busoni, Valeria ULg

in Thrall, Donald (Ed.) Veterinary Diagnostic Radiology (2007)

This chapter is part of a comprehensive book on veterinary diagnostic radiology and illustrates abnormal radiological features of stifle and tarsus disease in the horse. The best radiographic technique ... [more ▼]

This chapter is part of a comprehensive book on veterinary diagnostic radiology and illustrates abnormal radiological features of stifle and tarsus disease in the horse. The best radiographic technique for each disease is briefly described and ultrasonography is mentionned as a complementary examination when needed. More than 3O illustrations are available in the chapter. Chapter quizzes, key points and case studies are available on internet at http://evolve.elsevier.com/Thrall/vetrad. [less ▲]

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See detailProtection against abortion linked to gamma interferon production in pregnant dairy cows naturally infected with Neospora caninum
Lopez-Gatius, F.; Almeria, S.; Donofrio, G. et al

in Theriogenology (2007), 68(7), 1067-1073

Many immunological aspects of pregnancy, such as the role played by gamma interferon (IFN-gamma) in abortion, are not well understood. Neospora caninum is an intracellular protozoan considered to be among ... [more ▼]

Many immunological aspects of pregnancy, such as the role played by gamma interferon (IFN-gamma) in abortion, are not well understood. Neospora caninum is an intracellular protozoan considered to be among the main causes of abortion in cattle worldwide. The present study analyzes the interaction between IFN-gamma production and N. caninum infection in naturally infected pregnant cows. Data were obtained from 126 pregnant cows: 86 seropositive and 40 seronegative for the parasite. Pregnancy diagnosis and blood sample collection were performed on days 40, 90, 120, 150, 180 and 210 post-insemination or until the time of abortion detection. Plasma was tested for antibodies against N. caninum and IFN-gamma. Interferon-garmna was detected at some point along the pregnancy in 16 (19%) of the 86 Neospora-seropositive cows yet was undetectable in the 40 seronegative animals. Of the 126 pregnancies examined, 22 (17.5%) ended in abortion. Abortion occurred in 24.4% of seropositive cows (21/86) and in 2.5% of seronegative animals (1/40). Significant (P < 0.0001) interaction was observed between Neospora-seropositivity and IFN-gamma production. Based on the odds ratio, the risk of abortion was 15.6 times higher in seropositive cows not producing IFN-gamma than in seronegative animals, whereas neosporosis had no effect in seropositive cows with IFN-gamma production. A significant (P = 0.001) negative effect of IFN-gamma production on the Neospora titer was furthermore observed in the 65 non-aborting seropositive animals. These results indicate that IFN-gamma production affords protection against abortion in Neospora-infected cows and also point to a reduced humoral immune response to N. caninum during gestation in cows producing IFN-gamma. [less ▲]

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See detailPrise en charge de l'insuffisance mitrale fonctionnelle
Pierard, Luc ULg; LANCELLOTTI, Patrizio ULg

in Revue Médicale de Liège (2007), 62 Spec No

Functional mitral regurgitation (MR) is a frequent complication of systolic heart failure resulting from left ventricular remodeling and apical dispacement of the coaptation point. Functional MR is ... [more ▼]

Functional mitral regurgitation (MR) is a frequent complication of systolic heart failure resulting from left ventricular remodeling and apical dispacement of the coaptation point. Functional MR is associated with an increased mortality. It is characteristically dynamic. The dynamic component can be assessed and quantified by exercise Doppler echocardiography and has clinical and prognostic implications. Several therapeutic modalities can be used in the management of functional MR. Optimal medical treatment is mandatory. Selected patients are improved by cardiac resynchronization therapy. Mitral valve repair--undersized annuloplasty--can be useful but the indications are still controversial. Percutaneous annul loplasty is feasible. The first implantation in the world of one of the devices has been performed in CHU Liege. [less ▲]

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