References of "2006"
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See detailHoe staan vreemdelingen en allochtonen tegenover recht and gerecht in België?
Martiniello, Marco ULg; Foblets, Marie-Claire; Parmentier, Stephan et al

in Billiet, Jaak; Foblets, Marie-Claire; Vrielink, Jogchum (Eds.) Multiculturalisme Ontleed (2006)

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See detailEen kritisch laboratorium. Literatuurgeschiedenis in Franstalig België
Spinoy, Erik ULg; Haerens, Steven; Peeters, Patrick

in Freespace Nieuwzuid (2006), 6(21), 108-122

This is a translation of an article by Benoît Denis, on writing the history of French-Speaking literature in Belgium.

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See detailBruxelles face à ses défis. Préface
Martiniello, Marco ULg

in Lambert, Stéphane (Ed.) Bruxelles. Identités Plurielles (2006)

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See detailLes enjeux de la représentation politique dans les sociétés d'immigration : quelques réflexions sur le cas belge
Martiniello, Marco ULg

in Khader, Bichara; Martiniello, Marco; Rea, Andrea (Eds.) et al Penser l'immigration et l'intégration autrement. Une initiative belge inter-universitaire (2006)

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See detailPharmacological effects of tiludronate in horses after immobilisation
Delguste, Catherine ULg; Lepage, Olivier M; Doucet, Michèle et al

Poster (2006)

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See detailBiology of Posidonia
Gobert, Sylvie ULg; Cambridge, M. L.; Velimirov et al

in Larkum, Anthony WD; Orth, Robert J; Duarte, Carlos M (Eds.) Seagrasses: Biology, Ecology and Conservation (2006)

The aim of this chapter is to place emphasis on the dynamics of Posidonia systems in order to detect key ecosystem processes and to put in evidence the large differences between the Mediterranean and ... [more ▼]

The aim of this chapter is to place emphasis on the dynamics of Posidonia systems in order to detect key ecosystem processes and to put in evidence the large differences between the Mediterranean and Australian systems. These key processes shall be the basis to formulate new working hypothesis in order to verify newly emerging concepts and propose management plans in order to ensure the sustainability of the system. [less ▲]

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See detailAnalysis of Ser-His-Glu triad in alpha-amylases
Marx, Jean Claude; Feller, Georges ULg

Poster (2006)

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See detailThe neurotrophic receptor TrkB: a drug target in anti-cancer therapy ?
Desmet, Christophe ULg; Peeper, Daniel S.

in Cellular and Molecular Life Sciences : CMLS (2006), 63(7-8), 755-759

Increasing evidence implies altered signaling through the neurotrophic receptor tyrosine kinase TrkB in promoting tumor formation and metastasis. TrkB, sometimes in conjunction with its primary ligand ... [more ▼]

Increasing evidence implies altered signaling through the neurotrophic receptor tyrosine kinase TrkB in promoting tumor formation and metastasis. TrkB, sometimes in conjunction with its primary ligand BDNF, is often overexpressed in a variety of human cancers, ranging from neuroblastomas to pancreatic ductal adenocarcinomas, in which it may allow tumor expansion and contribute to resistance to anti-tumor agents. In vitro, TrkB acts as a potent suppressor of anoikis (detachment-induced apoptosis), which is associated with the acquisition of an aggressive tumorigenic and metastatic phenotype in vivo. In view of its predicted contribution to tumorigenicity and metastasis in humans, TrkB corresponds to a potential drug target, and preclinical models have already been established. The encouraging results of pharmacological Trk inhibitors in tumor xenograft models suggest that TrkB inhibition may represent a promising novel anti-tumor therapeutic strategy. This hypothesis is currently being evaluated in clinical trials. Here, we will discuss the latest developments on TrkB in these contexts as well as highlight some critical questions that remain to be addressed for evaluating TrkB as a therapeutic target in cancer [less ▲]

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See detailDNA in chromatin: from genome-wide sequence analysis to the modelling of replication in mammals
Arbeodo, Alain; d'Aubenton-Carafa, Y.; Audit, B. et al

in Advances in Chemical Physics (2006), 135

Understanding how chromatin is spatially and dynamically organized in the nucleus of eukaryotic cells and how this affects genome functions is one of the main challenges of cell biology. In that context ... [more ▼]

Understanding how chromatin is spatially and dynamically organized in the nucleus of eukaryotic cells and how this affects genome functions is one of the main challenges of cell biology. In that context the role of the DNA sequence itself in these condensation- decondensation processes is still debated. In this chapter, we explore large-scale nucleotide compositional fluctuations along the human genome through the optics of the wavelet transform microscope. Analysis of the GC content and of the TA and GC skews re- veals the existence of rhythms with characteristic fundamental frequencies that enlighten a remarkable cooperative organization of gene location and orientation. We describe a multi-scale methodology that allows us to predict 1012 replication origins in the 22 hu- man autosomal chromosomes. We present a model of replication with well-positioned replication origins and random termination sites that accounts for the highly relaxational nature of the oscillations observed in the skew profiles. We emphasize these putative replication initiation zones as regions where the chromatin fiber is likely to be more open so that DNA be more easily accessible. We show that, in the crowded environment of the cell nucleus, the presence of these intrinsic decondensed structural defects actually pre- disposes the fiber to spontaneously form multi-looped rosette-like structures that provide an attractive description of genome organization into replication foci that are observed in interphase mammalian nuclei as stable autonomous chromatin domains favoring com- partmentalized DNA replication and gene expression. New experimental perspectives are discussed. [less ▲]

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See detailLa qualité des services à l’ordre du jour
Pirard, Florence ULg

in Furet (Le) (2006), 49

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See detailPsychologisation ou transformation des modes de traitement social de la « question sociale » ?
Vrancken, Didier ULg

in Bresson, Maryse (Ed.) La psychologisation de l’intervention sociale : mythes et réalités (2006)

Envisageant la question de la problématisation d'une psychologisation du social, l'auteur propose une réflexion proposant davantage de partir des évolutions récentes des politiques sociales et de ... [more ▼]

Envisageant la question de la problématisation d'une psychologisation du social, l'auteur propose une réflexion proposant davantage de partir des évolutions récentes des politiques sociales et de considérer que nous évoluons plutôt dans une société du travail sur Soi de plus en plus confrontée à la montée de dispositifs individualisants. [less ▲]

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See detailBelgian agriculture and Europe
Burny, Philippe ULg

Speech (2006)

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See detailThe use of iso-inertial assessment in monitoring training effects
Jidovtseff, Boris ULg; Crielaard, Jean-Michel ULg; Croisier, Jean-Louis ULg

in Abstract Book “Exercise and muscle physiology” de l’Ecole Doctorale en Sciences de la Motricité (2006)

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See detailA mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep.
Clop, Alex; Marcq, Fabienne ULg; Takeda, Haruko ULg et al

in Nature Genetics (2006), 38(7), 813-8

Texel sheep are renowned for their exceptional meatiness. To identify the genes underlying this economically important feature, we performed a whole-genome scan in a Romanov x Texel F2 population. We ... [more ▼]

Texel sheep are renowned for their exceptional meatiness. To identify the genes underlying this economically important feature, we performed a whole-genome scan in a Romanov x Texel F2 population. We mapped a quantitative trait locus with a major effect on muscle mass to chromosome 2 and subsequently fine-mapped it to a chromosome interval encompassing the myostatin (GDF8) gene. We herein demonstrate that the GDF8 allele of Texel sheep is characterized by a G to A transition in the 3' UTR that creates a target site for mir1 and mir206, microRNAs (miRNAs) that are highly expressed in skeletal muscle. This causes translational inhibition of the myostatin gene and hence contributes to the muscular hypertrophy of Texel sheep. Analysis of SNP databases for humans and mice demonstrates that mutations creating or destroying putative miRNA target sites are abundant and might be important effectors of phenotypic variation. [less ▲]

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See detailRecombinant bovine herpesvirus 4 (BoHV-4) expressing glycoprotein D of BoHV-1 is immunogenic and elicits serum-neutralizing antibodies against BoHV-1 in a rabbit model.
Donofrio, Gaetano; Cavirani, Sandro; Vanderplasschen, Alain ULg et al

in Clinical and Vaccine Immunology (2006), 13(11), 1246-54

Several biological characteristics of bovine herpesvirus 4 (BoHV-4) make it a good candidate as a gene delivery vector for vaccination purposes. These characteristics include little or no pathogenicity ... [more ▼]

Several biological characteristics of bovine herpesvirus 4 (BoHV-4) make it a good candidate as a gene delivery vector for vaccination purposes. These characteristics include little or no pathogenicity, unlikely oncogenicity, the capability to accommodate large amounts of foreign genetic material, the ability to infect several cell types coming from different animal species, and the ability to maintain transgene expression in both undifferentiated and differentiated cells. Starting from BoHV-4 cloned as a bacterial artificial chromosome (BAC), we used MuA transposase-mediated in vitro transposition to generate recombinant BoHV-4 expressing the immunodominant glycoprotein D (gD) of BoHV-1, one of the most important pathogens of cattle. Although a cis-acting element from woodchuck hepatitis virus (the woodchuck hepatitis virus posttranscriptional regulatory element [WPRE]) in the 3' end of the gD expression cassette was required for maximal gD expression from plasmids in transient transfection assays, this element was not necessary for efficient expression of gD from recombinant BoHV-4 genomes. BoHV-4 recombinants containing gD expression cassettes with or without the WPRE expressed gD at similarly high levels. Several cell lines originating from different animal species expressed gD when infected with BoHV-4 recombinants. When rabbits were immunized with one of the recombinants, high levels of serum neutralizing antibodies against BoHV-1 were generated. This work is one of the first demonstrations of the use BoHV-4 as a vector for vaccine purposes and may provide the basis for BoHV-1 vaccination of cattle with recombinant BoHV-4. [less ▲]

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See detailElectroantennogram of Culex quinquefasciatus Say (Diptera:Culicidae) to chemical compounds from fermented infusions and improvement of gravid mosquito trapping
Latte, Nicolas ULg

Master's dissertation (2006)

The urban mosquito Culex quinquefasciatus Say (Diptera: Culicidae) uses chemicals to locate suitable water pools for oviposition. These chemicals when identified can be used to trap gravid female ... [more ▼]

The urban mosquito Culex quinquefasciatus Say (Diptera: Culicidae) uses chemicals to locate suitable water pools for oviposition. These chemicals when identified can be used to trap gravid female mosquitoes. Experiments in Davis and in Sacramento (California, in the United States) were made to improve the trapping efficiency of Reiter/Cumming gravid traps baited by several attractants (or attractant blends). Unfortunately, it appeared that the number of gravid female mosquitoes collected was not sufficient to differentiate the efficacy of attractant blends tested by statistical analysis. However, a positive correlation between the total mosquito number collected daily and the highest humidity shows that the mosquito oviposition activity seems to be influenced by the humidity during the night. Observations on total number of mosquitoes and the highest temperature seem to reveal a threshold temperature which is critical for the adult mosquito survival. A coupled gas chromatography – electronantennography (GC-EAD) protocol was also developed step by step in order to find new Culex quinquefasciatus oviposition attractants. After obtaining repetitive electroantennographic (EA) response, two comparison experiments (SPME fiber type and infusion type) were made to finalize the specific GC-EAD/SPME protocol. This with the aim to prospect new attractants from fermented Bermuda grass infusion. Analyses based on all results permit to distinguish the EA responses from random perturbations (electromagnetic and vibration). GC-EAD/SPME of Bermuda grass infusion analyses confirms the presence of 10 and the activity of 9 chemical compounds as established by Du and Millar in 1999. Furthermore, experiments on Culex quinquefasciatus performed with the new protocol, brought to light the EA activity of 10 other unknown chemicals, 7 of which are low molecular weight chemical compounds. These new chemicals have now to be identified and their ability to elicit EA responses still has to be confirmed. [less ▲]

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See detailCompte rendu de David BRADSHAW, "Aristotle East and West. Metaphysics and the Division of Christendom"
Gavray, Marc-Antoine ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2006), 75

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See detailEtude de la diversité des pucerons et des auxiliaires adiphages relative à la présence d'orties en bordures de champ
Alhmedi, A.; Francis, Frédéric ULg; Bodson, Bernard ULg et al

in Notes Fauniques de Gembloux (2006), 59(2), 121-124

Detailed reference viewed: 33 (6 ULg)