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See detailNumerical simulation of blaststructure interaction
Noels, Ludovic ULg; Radovitzky, Raul

Conference (2006)

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See detailAnalytical validation of potentiometric method for cetirizinium ion
Rachidi, Mohamed ULg; Digua, K.; Hubert, Philippe ULg et al

in Analytical Letters (2006), 39(8), 1699-1708

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required ... [more ▼]

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required. In this matter, many official documents describing the criteria of validation are available. However, these concern mainly chromatography analysis and bio-analytical methods of pharmaceutical products, but they do not propose any experimental protocol for direct potentiometric methods using ion-selective electrodes applied in pharmaceutical analysis. In this work, we are proposing a validation strategy based on the normative and regulatory guidelines applied to a potentiometric method with a polymeric membrane selective to cetirizine dihydrochloride. The statistical analysis obtained from raw data is described for all steps of this protocol. Also this validated method was successfully applied to the determination of cetirizine in pharmaceutical preparations using direct potentiometry with a mean relative standard deviation of 0.57% and a mean recovery of 99.63%. [less ▲]

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See detailSuppression of pattern recognition receptor TLR4 sensing does not alter lung responses to pneumovirus infection
Faisca, Pedro; Bui Tran Anh, Dao; Thomas, Anne et al

in Microbes & Infection (2006), 8

Toll-like receptors (TLR) are an important component in the innate immune response to a wide variety of pathogens. Recently, a series of studies has addressed the hypothesis that TLR4 also participates in ... [more ▼]

Toll-like receptors (TLR) are an important component in the innate immune response to a wide variety of pathogens. Recently, a series of studies has addressed the hypothesis that TLR4 also participates in the host innate response against respiratory syncytial virus (RSV), the leading cause of lower respiratory tract infections in infants and young children. In most of the studies available, RSV, which is not a natural pathogen of mice, has been systematically used in mouse models of human bronchiolitis, with conflicting results. Pneumonia virus of mice (PVM), a member of the pneumovirus genus, shares many similarities with RSV. The serological and structural relationships that exist between them suggest that the immune response to these viruses may be similar in their respective natural hosts. To determine the role of TLR4 in host defense against PVM, TLR4-competent and TLR4-deficient mice were intranasally infected with PVM. Variation of body weight, pulmonary function values, histopathology, and pulmonary viral loads were analyzed. None of the investigated clinical, functional, histological and virological parameters was different between strains, which demonstrates that the sensitivity of the mouse to its natural pneumovirus infection is independent of the presence or absence of TLR4 sensing. [less ▲]

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See detailPalyWeb
Steemans, Philippe ULg; Breuer, P.

Conference (2006)

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See detailLangues et immigration dans l’enseignement en Communauté française de Belgique
Lucchini, Silvia ULg

in Conseil supérieur de la langue française et Service de la langue française de la Communauté française de Belgique (Ed.) Langue française et diversité linguistique (2006)

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See detailInclusion of a stress-dependent Preisach model in 2D FE calculations
Benabou, A.; Vandenbossche, L.; Gyselinck, Johan et al

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2006), 25(1), 81-90

Purpose - Mechanical stress can heavily affect the magnetic behaviour law in ferromagnetic materials. This paper, aims to take into account the effect of mechanical stress into a hystreresis model. This ... [more ▼]

Purpose - Mechanical stress can heavily affect the magnetic behaviour law in ferromagnetic materials. This paper, aims to take into account the effect of mechanical stress into a hystreresis model. This model is implemented in a finite element analysis code and tested in the case of a simple system. Design/methodology/approach - A simple extension of the classical Preisach model is proposed, in which a function linked to the Preisach density is parameterized using the mechanical stress as a supplementary parameter. The methodology is based on experimental measurements for identifying the required function. As a first approach, a linear interpolation is used between the measurements in order to have a continuous evolution of the magneto-mechanical behaviour. This model has been tested in the case of a steel sheet in which width is not constant in order to obtain a non-uniform distribution of stress and magnetic flux density. Findings - The model can predict the magneto-mechanical behaviour with a good accuracy in the case of tensile stress. Implementation of the model in finite element analysis has shown that the model can predict the behaviour of steel sheet subject to a non-uniform stress distribution. Originality/value - This paper shows that a classical hysteresis model can be extended to take into account the magneto-mechanical behaviour. This is useful for the design of electrical machines which are subject to non-negligible mechanical stress. [less ▲]

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See detailNonlocal magnetic field-tuned quantum criticality in cubic CeIn3-xSnx (x=0.25)
Silhanek, Alejandro ULg; Ebihara, Takao; Harrison, N. et al

in Physical Review Letters (2006), 96(20),

We show that antiferromagnetism in lightly (approximate to 8%) Sn-doped CeIn3 terminates at a critical field mu H-0(c)=42 +/- 2 T. Electrical transport and thermodynamic measurements reveal the effective ... [more ▼]

We show that antiferromagnetism in lightly (approximate to 8%) Sn-doped CeIn3 terminates at a critical field mu H-0(c)=42 +/- 2 T. Electrical transport and thermodynamic measurements reveal the effective mass m(*) not to diverge, suggesting that cubic CeIn3 is representative of a critical spin-density wave (SDW) scenario, unlike the local quantum critical points reported in anisotropic systems such as CeCu6-xAux and YbRh2Si2-xGex. The existence of a maximum in m(*) at a lower field mu H-0(x)=30 +/- 1 T may be interpreted as a field-induced crossover from local moment to SDW behavior as the Neel temperature falls below the Fermi temperature. [less ▲]

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See detailRadiographic and ultrasonographic findings of emphysematous cystitis in four nondiabetic female dogs
Petite, A.; Busoni, Valeria ULg; Heinen, Marie-Pierre ULg et al

in Veterinary Radiology & Ultrasound (2006), 47(1), 90-93

The urinary bladder of four dogs with emphysematous cystitis was assessed radiographically. Ultrasonography was also performed using a 7.5-MHz microconvex probe in dorsal recumbency and in a standing ... [more ▼]

The urinary bladder of four dogs with emphysematous cystitis was assessed radiographically. Ultrasonography was also performed using a 7.5-MHz microconvex probe in dorsal recumbency and in a standing position. Ultrasonographically there were bright echoes and reverberations typical of gas in all dogs. This was entrapped in the bladder wall as it appeared in the same location in recumbent and standing positions. Bladder size was reduced and bladder content was echogenic in all dogs. In only one out of the four dogs was a gas stripe seen in the bladder on radiographs. Proteus mirahilis was isolated from the urine of all patients. Diabetes was ruled out on the basis of urine and blood analysis. A small amount of gas can be difficult to detect on radiographs. Ultrasonography appears to be a more sensitive technique for detection of gas within the bladder at an early stage of emphysematous cystitis. Prevalence of emphysematous cystitis may be underestimated if only radiographs are made. [less ▲]

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See detailOrbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia
Peters, Frederic; Perani, Daniela; Herholz, Karl et al

in Dementia & Geriatric Cognitive Disorders (2006), 21(5-6), 373-379

Orbitofrontal metabolic impairment is characteristic of the frontal variant of frontotemporal dementia (fv-FTD), as are early changes in emotional and social conduct. Two main types of behavioral ... [more ▼]

Orbitofrontal metabolic impairment is characteristic of the frontal variant of frontotemporal dementia (fv-FTD), as are early changes in emotional and social conduct. Two main types of behavioral disturbances have been distinguished in fv-FTD patients: apathetic and disinhibited manifestations. In this study, we searched for relationships between brain metabolism and presence of apathetic or disinhibited behavior. Metabolic activity and behavioral data were collected in 41 fv-FTD patients from European PET centers. A conjunction analysis of the PET data showed an expected impairment of metabolic activity in the anterior cingulate, ventromedial and orbital prefrontal cortex, the dorsolateral prefrontal cortex and the left anterior insula in fv-FTD subjects compared to matched controls. A correlation was observed between disinhibition scores on the Neuropsychiatric Inventory scale and a cluster of voxels located in the posterior orbitofrontal cortex ( 6, 28, - 24). Comparison of brain activity between apathetic and nonapathetic fv-FTD patients from two centers also revealed a specific involvement of the posterior orbitofrontal cortex in apathetic subjects ( 4, 22, - 22). The results confirm that the main cerebral metabolic impairment in fv-FTD patients affects areas specializing in emotional evaluation and demonstrate that decreased orbitofrontal activity is related to both disinhibited and apathetic syndromes in fv-FTD. Copyright (C) 2006 S. Karger AG, Basel. [less ▲]

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See detailFeasibility of STAP for passive GSM-based radar
Neyt, Xavier; Raout, J.; Kubika, Virginie et al

Conference (2006)

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