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See detailComparison of impacts of dams on the annual maximum flow characteristics in three regulated hydrological regimes in Quebec (Canada).
Assani, A. A.; Stichelbout, E.; Roy, A. G. et al

in Hydrological Processes (2006)

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See detailA role for proneural genes in the maturation of cortical progenitor cells.
Britz, Olivier; Mattar, Pierre; Nguyen, Laurent ULg et al

in Cerebral Cortex (2006), 16 Suppl 1

We showed previously that the proneural genes Neurogenin1 (Ngn1) and Ngn2 are required to specify the phenotypes of early- and not late-born neurons in the neocortex, acting in part through repression of ... [more ▼]

We showed previously that the proneural genes Neurogenin1 (Ngn1) and Ngn2 are required to specify the phenotypes of early- and not late-born neurons in the neocortex, acting in part through repression of Mash1, a third cortically expressed proneural gene. The precise timing of Ngn1/2 specification activity was unexpected given these genes are expressed throughout cortical development, prompting us to search for a later function. Here we reveal that Ngn2 and Mash1 are expressed in a dynamic fashion, acquiring a cell cycle-biased, nonoverlapping distribution, with preferential expression in prospective basal progenitors, during mid corticogenesis. We also identified a new function for Ngn2 during this latter period, demonstrating that it is required to regulate the transit of cortical progenitors from the ventricular zone (VZ) to the subventricular zone. Notably, Ngn2 regulates progenitor maturation at least in part through repression of Mash1 as misexpression of Mash1 strongly enhanced progenitor cell exit from the VZ. Significantly, the ability of Mash1 to promote progenitor cell maturation occurred independently of its ability to respecify cortical cells and is thus a novel function for Mash1. Taken together, these data support a model whereby Ngn2 and Mash1 function together to regulate the zonal distribution of progenitors in the developing neocortex. [less ▲]

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See detailLes livres imprimés en langue française avant 1500 dans les Pays-Bas méridionaux : réflexions sur leur mise en page
Adam, Renaud ULg

in Van Hemelryck, Tania; Van Hoorebeeck, Céline (Eds.) L'écrit et le manuscrit à la fin du Moyen Age : actes du IIème colloque international du Groupe de recherche sur le moyen français (2006)

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See detailProneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.
Castro, Diogo S; Skowronska-Krawczyk, Dorota; Armant, Olivier et al

in Developmental Cell (2006), 11(6), 831-44

Proneural proteins play a central role in vertebrate neurogenesis, but little is known of the genes that they regulate and of the factors that interact with proneural proteins to activate a neurogenic ... [more ▼]

Proneural proteins play a central role in vertebrate neurogenesis, but little is known of the genes that they regulate and of the factors that interact with proneural proteins to activate a neurogenic program. Here, we demonstrate that the proneural protein Mash1 and the POU proteins Brn1 and Brn2 interact on the promoter of the Notch ligand Delta1 and synergistically activate Delta1 transcription, a key step in neurogenesis. Overexpression experiments in vivo indicate that Brn2, like Mash1, regulates additional aspects of neurogenesis, including the division of progenitors and the differentiation and migration of neurons. We identify by in silico screening a number of additional candidate target genes, which are recognized by Mash1 and Brn proteins through a DNA-binding motif similar to that found in the Delta1 gene and present a broad range of activities. We thus propose that Mash1 synergizes with Brn factors to regulate multiple steps of neurogenesis. [less ▲]

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See detailNyungwea, a new genus of lichen with goniocyst-producing stipes from Rwanda and Uganda (East Africa)
Sérusiaux, Emmanuel ULg; Fischer, E.; Killmann, D.

in Lichenologist (2006), 38(Part 2), 115-121

The new genus and species Nyungwea pallida is characterized by a thin thallus lichenized with Trentepohlia and pale stipes producing goniocysts. Its taxonomic position is uncertain. It is named after the ... [more ▼]

The new genus and species Nyungwea pallida is characterized by a thin thallus lichenized with Trentepohlia and pale stipes producing goniocysts. Its taxonomic position is uncertain. It is named after the large pristine montane forest of Nyungwe in Rwanda (East Africa) where it was first found; it is also known from the Mabira forest in Uganda. [less ▲]

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See detailThe role of sleep in the consolidation of emotional memories in humans : a fMRI study
Sterpenich, Virginie; Albouy, Geneviève ULg; Boly, Mélanie ULg et al

Poster (2006)

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See detailJacques IZOARD, Œuvres complètes, Volume II : Poésies 1979-2000
Purnelle, Gérald ULg

Book published by La Différence (2006)

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See detailAnalytic properties of unitarization schemes
Selyugin, Oleg Viktorovich; Cudell, Jean-René ULg

in Czechoslovak Journal of Physics (2006)

The analytic properties of the elastic hadron scattering amplitude are examined in the impact parameter representation at high energies. Different unitarization procedures and the corresponding non-linear ... [more ▼]

The analytic properties of the elastic hadron scattering amplitude are examined in the impact parameter representation at high energies. Different unitarization procedures and the corresponding non-linear equations are presented. Several unitarisation schemes are presented. They lead to almost identical results at the LHC. [less ▲]

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See detailRenaissance de l’Égypte aux Temps Modernes. De l’intérêt pour la civilisation pharaonique et ses hiéroglyphes à Liège au XVIe siècle
Laboury, Dimitri ULg

in Warmenbol, Eugène (Ed.) La Caravane du Caire. L’Égypte sur d’autres rives (2006)

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See detailQuantum reversibility and echoes in interacting systems
Petitjean, Cyril ULg; Jacquod, Ph

in PHYSICAL REVIEW LETTERS (2006), 97(12), 124103-4

In echo experiments, imperfect time-reversal operations are performed on a subset of the total number of degrees of freedom. To capture the physics of these experiments, we introduce a partial fidelity M ... [more ▼]

In echo experiments, imperfect time-reversal operations are performed on a subset of the total number of degrees of freedom. To capture the physics of these experiments, we introduce a partial fidelity M(B)(t), the Boltzmann echo, where only part of the system's degrees of freedom can be time reversed. We present a semiclassical calculation of M(B)(t). We show that, as the time-reversal operation is performed more and more accurately, the decay rate of M(B)(t) saturates at a value given by the decoherence rate of the controlled degrees of freedom due to their coupling to uncontrolled ones. We connect these results with NMR spin echo experiments. [less ▲]

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See detailUne seconde session qui commence mal...
Wildemeersch, Jonathan ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2006), (26), 1132-1142

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See detailLa saga des inhibiteurs des histone-desacetylases: de la TSA au SAHA
Peixoto, Paul ULg; Lansiaux, Amelie

in Bulletin du Cancer (2006), 93(1), 27-36

Histone-deacetylase inhibitors (HDCACi) represent a new class of antitumor agents currently in clinical development. They target a family of enzymes which catalyse histone acetylation modifications, in ... [more ▼]

Histone-deacetylase inhibitors (HDCACi) represent a new class of antitumor agents currently in clinical development. They target a family of enzymes which catalyse histone acetylation modifications, in particular for histones H2A, H2B, H3 and H4. These proteins stabilize the nucleosome core, fundamental unity of chromatin which represents the first level of DNA nuclear compaction. The balance of histone acetylation is maintained by histone-acetyltransferases (HAT) and histone-deacetylases (HDAC) which play an important role in gene transcription. Alterations of HDACs were identified in tumor cells and contribute to the massive perturbations of gene expression in numerous tumors. HDAC inhibition leads to differentiation, cell cycle arrest and apoptosis in tumor cells. HDACi efficiently prevent tumor growth in a variety of in vivo preclinical models. Several structurally distinct classes of HDACi have entered in clinical trials and a significant antitumor activity was reported in several cases. However, a better understanding of the biological effects of this class of enzymes is mandatory for the successful development of these new antitumoral agents. In this review, are exposed the main drug candidates in clinical development. In the near future, it will be interesting to define direct relationships between specific inhibition of one or several HDAC and the subsequent HDAC-dependent antitumor effects to define a new generation of specific histone-deacetylase inhibitors. [less ▲]

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See detailPercutaneous coronary intervention for bifurcation disease.A consensus view from the first meeting of the European Bifurcation Club.
Thomas, Martyn; Hildick-Smith, David; Louvard, Yves et al

in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (2006), 2(2), 149-53

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See detailSheep do have opinions
Despret, Vinciane ULg

in Latour Bruno, Weibel Peter (Ed.) Making Things Public. Atmospheres of Democracy (2006)

For the past few years the inhabitants of a hamlet on the outskirts of the village of Ingleton in Yorkshire, England, have been witnessing a strange exercise every morning. A woman, said to have been one ... [more ▼]

For the past few years the inhabitants of a hamlet on the outskirts of the village of Ingleton in Yorkshire, England, have been witnessing a strange exercise every morning. A woman, said to have been one of the most renowned primatologists in the English-speaking world, spends her day in a field in front of her house, observing animals that she has put there. As she did during her many years of field work in Africa studying apes, primatologist Thelma Rowell patiently notes all the movements, anecdotes and tiny events making up the daily social life of the animals to which she is currently devoting her time. Admittedly, these animals are different to the ones she was used to spending time with: the relations are not characterized by the same intensity, the behaviors are peculiar to the species, the communication does not always pass by the same channels, and the events seem to take place at another pace. But as far as their social expertise is concerned, these animals are certainly on a par with apes. [less ▲]

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See detailUltimate limit state design technology for aluminum multi-hull ship structures
PAIK, Jeom; HUghes, Owen; Rigo, Philippe ULg

in Transactions - Society of Naval Architects and Marine Engineers (2006), 113

The present paper is a summary of recent research and developments related to some core ultimate limit state (ULS) technologies for design and strength assessment of aluminum multi-hull ship structures ... [more ▼]

The present paper is a summary of recent research and developments related to some core ultimate limit state (ULS) technologies for design and strength assessment of aluminum multi-hull ship structures, jointly undertaken by Pusan National University, Virginia Tech, U.S. Naval Surface Warfare Center and Alcan Marine. An extensive study on the subject has been undertaken by the authors theoretically, numerically and experimentally. Methods to analyze hull girder loads I load effects, stiffened panel ultimate strength and hull girder ultimate strength of aluminum multi-hull ship structures are developed in the present study. Application examples of the methodologies for the ULS structural design and strength assessment of a hypothetical 120m long all aluminum catamaran fast ship structure are presented. Important insights and conclusions developed from the present study are summarized. Some of the comparisons have shown that 5383 called Sealium (a patented Alcan Marine alloy) is superior to the standard aluminum alloy 5083 in terms of material properties, ULS characteristics and welding performance. It is our hope that the methods developed from the present study will be useful for ULS design and strength assessment of aluminum multi-hull ship structures. [less ▲]

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