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See detailPeut-on gérer la forme urbaine ? Les enjeux de la régulation morphologique (France, Angleterre, Etats-Unis)
Teller, Jacques ULg

in Descat, S.; Siret, D. (Eds.) La ville durable au risque de l’histoire (2006)

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See detailInvestigation on genotype by environment interaction for milk yield of Holstein cows in Luxembourg and Tunisia
Hammami, Hedi ULg; Croquet, Coraline; Soyeurt, Hélène ULg et al

in INTERBULL Bulletin (2006), 35

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See detailElevated MMP-12 protein levels in induced sputum from patients with COPD
Demedts, Inge K.; Morel-Montero, A.; Lebecque, S. et al

in Thorax (2006), 61(3), 196-201

Background: Several matrix metalloproteinases ( MMPs) are involved in the pathogenesis of chronic obstructive pulmonary disease ( COPD). In mice, MMP-12 plays a crucial role in the development of ... [more ▼]

Background: Several matrix metalloproteinases ( MMPs) are involved in the pathogenesis of chronic obstructive pulmonary disease ( COPD). In mice, MMP-12 plays a crucial role in the development of cigarette smoke induced emphysema. A study was undertaken to investigate the role of MMP-12 in the development of COPD in human smokers. Methods: Induced sputum samples were collected from patients with stable COPD (n = 28), healthy smokers ( n = 14), never smokers ( n = 20), and former smokers ( n = 14). MMP-12 protein levels in induced sputum were determined by ELISA and compared between the four study groups. MMP-12 enzymatic activity in induced sputum was evaluated by casein zymography and by cleaving of a fluorescence quenched substrate. Results: Median (IQR) MMP-12 levels were significantly higher in COPD patients than in healthy smokers, never smokers, and former smokers (17.5 (7.1 - 42.1) v 6.7 (3.9 - 10.4) v 4.2 (2.4 - 11.3) v 6.1 (4.5 - 7.6) ng/ml, p = 0.0002). MMP-12 enzymatic activity was significantly higher in patients with COPD than in controls (4.11 (1.4 - 8.0) v 0.14 (0.1 - 0.2) mu g/ml, p = 0.0002). Conclusion: MMP-12 is markedly increased in induced sputum from patients with stable COPD compared with controls, suggesting a role for MMP-12 in the development of COPD in smokers. [less ▲]

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See detailSome comments on the Parametric Fire Model of Eurocode 1
Reitgrüber, Stefan; Pérez-Jimenez, Christian; Di Blasi, Colomba et al

Conference (2006)

In this paper, the modifications that have been recently introduced in the parametric fire model of Eurocode 1 are presented. The reasons behind these modifications are given. Some Problems that have been ... [more ▼]

In this paper, the modifications that have been recently introduced in the parametric fire model of Eurocode 1 are presented. The reasons behind these modifications are given. Some Problems that have been discovered in the present formulation are highlighted, namely the fact that the model is not continuous and the fact that the heat release of wood that has been used for the calibration of the model is not consistent anymore with the value that is now recommended in the Eurocode. A proposal is made that makes the model continuous. A new calibration of this modified model has been made on the base of the now recommended value of the heat release of wood with comparison to the results of some 50 full scale experimental fire tests. [less ▲]

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See detailStrategy for the qualitative and quantitative analysis of crop syrup containing enzymatically produced Isomaltooligosaccharides known as emerging prebiotics.
Goffin, Dorothée ULg; Blecker, Christophe ULg; Wathelet, Bernard ULg et al

Poster (2006)

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. Recent data obtained in human ... [more ▼]

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. Recent data obtained in human subjects, support the involvement of dietary oligosaccharides in physiological processes in the different intestinal cell type and also outside the gastrointestinal tract (e.g. hormone production, lipid and carbohydrate metabolism). IMOs consists of glucose monomers linked by at least one α-1-6, or in a lower proportion α -1-3 (nigerose family) or α -1-2 (kojibiose family) glucosidic linkages. In our case they are produced enzymatically from corn starch. It results in a very complex mixture with molecules characterized at the same time by their DP value (from 2 to ~20), linkages types (α-1-2, 3 or 6) and the proportion and position of each type of linkage (only α -1-6 or combined types). The challenge of this study was to find a qualitative and quantitative method to characterize the syrups. In a subsequent study, every unidentified peak could be determined by NMR or Mass spectrometry. Three different chromatographic methods have been tested and compared over their selectivity, sensibility, robustness, applicability and their quantitative power. The HPLC-RID (Refractive Index Detector) used with a Prevail Carbohydrate column (Alltech), adapted for carbohydrates with a certain value of DP, appear to be poorly selective due to the obligation of working in isocratic conditions. The HPLC-ELSD (Evaporating Light Scattering Detector) used with the same column gave a very good separation upon the DP as the Prevail accepts a wide range of solvant changing and even a separation of the different DP 2 molecules. The sensibility was also improved due to the stability of the baseline. The quantitative analysis is a bit more awkward due to the relatively limited linear portion of the calibration curve. High-performance Anion Exchange Chromatography coupled with Pulsed Amperometric Detection (HPAEC-PAD) appeared to deserve a special mention, since it provides selective separation and sensitive detection. In fact, this technique is the only chromatographic one to separate with effectiveness homologue molecules having a difference only in their DP (up to high DPs) or linkage types. This is due to the separation mode based on the difference in ionic force of the sugars in alkaline conditions (mainly due to the DP and the structure of the molecule). However, during the detection, the electrochemical behavior of carbohydrates can be affected by molecular weight as well as by structural differences giving rise to different response factors; as a consequence, HPAEC-PAD is not generally considered as suitable for quantitative studies of complex mixtures of oligosaccharides. In this work a methodological approach is presented in order to get a quantitative response through a rigorous methodology for our IMOs. It also opens the way to the theoretical determination of the response factor for the homologue molecules in relation with their structure and DP. [less ▲]

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See detailAchromatic optical vortex coronagraph with subwavelength gratings
Mawet, Dimitri ULg; Riaud, Pierre ULg; Baudrand, J. et al

in Proceedings of the Coronagraph Workshop (2006)

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See detailThe Treatment of Severe Postmenopausal Osteoporosis : A Review of Current and Emerging Therapeutic Options
Reginster, Jean-Yves ULg; Sarlet, Nathalie ULg

in Treatments in Endocrinology (2006), 5(1), 15-23

Several chemical entities have shown their ability to reduce axial and/or appendicular fractures in patients with osteoporosis. Since patients who have experienced a previous fracture are at high risk for ... [more ▼]

Several chemical entities have shown their ability to reduce axial and/or appendicular fractures in patients with osteoporosis. Since patients who have experienced a previous fracture are at high risk for subsequent vertebral or hip fracture, it is of prime importance to treat such patients with medications that have unequivocally demonstrated their ability to reduce fracture rates in patients with prevalent fractures. Results obtained with calcium and vitamin D, in this particular population, are not fully satisfactory and these medications are probably better used in conjunction with other therapeutic regimens. Bisphosphonates have shown their ability to reduce vertebral (alendronate, risedronate, ibandronate) and non-vertebral (alendronate, risedronate) fractures in patients with established osteoporosis. Raloxifene has also shown similar properties, notwithstanding its effect on non-vertebral fractures, which has only been derived from a post hoc analysis limited to patients with prevalent severe vertebral fractures at baseline. This compound also has interesting non-skeletal benefits, including effects on the breast and heart. Teriparatide, a bone-forming agent, promptly reduces the rate of vertebral and all non-vertebral fractures, without significant adverse effects. Strontium ranelate, the first agent shown to concomitantly decrease bone resorption and stimulate bone formation, has also shown its ability to reduce rates of vertebral and non-vertebral fractures in patients with established osteoporosis. It significantly reduces hip fractures in elderly individuals at high risk for such events. Its safety profile is also excellent. [less ▲]

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See detailL'accompagnement : une fonction multiforme, un contrat clair à établir d'emblée
Poumay, Marianne ULg

Learning material (2006)

La fonction d'accompagnateur est aujourd'hui répandue à travers de nombreux secteurs professionnels. Le présent document se propose de mobiliser deux auteures, Pierrette Massé et Maëlla Paul, pour dégager ... [more ▼]

La fonction d'accompagnateur est aujourd'hui répandue à travers de nombreux secteurs professionnels. Le présent document se propose de mobiliser deux auteures, Pierrette Massé et Maëlla Paul, pour dégager les caractéristiques essentielles de l'accompagnement et une taxonomie des postures d'accompagnement. Cette modélisation peut guider vers une classification empirique d'accompagnements réalisés dans le cadre de programmes tels "Formadis". [less ▲]

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See detailSelection of antagonists against Penicillium expansum and Botrytis cinerea, two postharvest apple parasites
Achbani, E. H.; Mounir, R.; El Jaafari, S. et al

Conference (2006)

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See detailCe que l'annuaire fait à Internet: Sociologie des épreuves documentaires
Lejeune, Christophe ULg

in Cahiers de la Documentation = Bladen voor Documentatie (2006), 60(3), 12-22

Internet regorge de communautés de passionnés en tous genres. C'est de l'une d'elles que traite cette contribution. Lancée en 1998. l'initiative en question regroupe des volontaires construisant un ... [more ▼]

Internet regorge de communautés de passionnés en tous genres. C'est de l'une d'elles que traite cette contribution. Lancée en 1998. l'initiative en question regroupe des volontaires construisant un annuaire de sites Internet. Bien avant le succès de Wikipédia, cette communauté est loin d'avoir laissé indifférents les géants de l'informatique puisque Netscape l'a sponsorisée depuis ses débuts et que le service d'annuaire de Google utilise sa base de données. Apparemment éloigné des bibliothèques, ce groupe de passionnés n'en est pas moins en train de réaliser le rêve de Paul Otlet, pionnier (belge) de la documentation. En effet, en collectant les adresses de sites Internet, en les répertoriant, les classant, ces personnes reproduisent, un siècle plus tard, ce qui fut le travail des premiers documentalistes. Ils se confrontent à des problèmes similaires. Ils y trouvent souvent des solutions analogues. Et, parfois, leurs solutions divergent. Après quatre années d'observation fouillée de cette communauté virtuelle, l'auteur propose une mise en perspective de cette activité classificatoire avec les usages et les outils de la documentation. [less ▲]

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See detailRésumé CEDH, 11 octobre 2005, NA et autres c. Turquie
Delnoy, Michel ULg

in Aménagement - Environnement (2006), 2

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See detailLa Censure de l’imprimé. Belgique, France, Québec et Suisse romande. XIXe et XXe siècles
Durand, Pascal ULg; Hébert, P.; Mollier, J.-Y. et al

Book published by Nota Bene (2006)

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See detailMetal catalysts suppported on texture-tailored carbon xerogels
Job, Nathalie ULg; Léonard, Angélique ULg; Colomer, Jean-François et al

in Studies in Surface Science and Catalysis (2006), 162

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See detailSelection of bacteria to decrease in vitro growth of Campylobacter jejuni and Campylobacter coli and characterization of their antagonistic activities
Marcq, Christopher ULg; Didderen, Isabelle; Dubois Dauphin, Robin ULg et al

in Proceedings of the Eleventh Conference on Food Microbiology (2006)

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See detailTools to assess iodine deficiency in calves born from deficient and non deficient dams
Guyot, Hugues ULg; Uyttenhoef, Aude; Lebreton, Pascal et al

Poster (2006)

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See detailAccuracy and precision : total error vs 4-6-30
Boulanger, Bruno ULg; Dewé, Walthère ULg; Hubert, Philippe ULg et al

Conference (2006)

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See detailAnalytical validation of the new plasma calibrated Accu-Chek (R) Test Strips (Roche Diagnostics)
Meex, Cécile ULg; Poncin, José ULg; Chapelle, Jean-Paul ULg et al

in Clinical Chemistry & Laboratory Medicine (2006), 44(11), 1376-1378

Background: The Accu-Chek Inform glucose monitor is a point-of-care system for testing blood glucose. New test strips, calibrated to deliver glucose plasma-like values, were launched on the market in May ... [more ▼]

Background: The Accu-Chek Inform glucose monitor is a point-of-care system for testing blood glucose. New test strips, calibrated to deliver glucose plasma-like values, were launched on the market in May 2005. The aim of our study was to perform analytical validation of these new strips. Methods: We compared the new plasma strips with whole blood strips; results for the plasma strips with plasma values obtained using a clinical analyzer and with whole blood values given by the glucose electrode of a blood gas analyzer; and the influence of the type of blood (capillary or venous) on the results obtained by the glucose monitor with the plasma calibrated strips. Results: Plasma strips give on average 7% higher results than the previous whole blood strips. However, the results given by the plasma strips on capillary whole blood, even if well correlated, are not completely comparable with those given by an analyzer for venous plasma. Nevertheless, these plasma strips and the glucose electrode of a blood gas analyzer give comparable results. Conclusions: Accu-Chek Inform plasma strips are a good method for monitoring of blood glucose values in patients with diabetes. [less ▲]

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See detailLa Villa des Papyrus et les rouleaux d'Herculanum
Delattre, Daniel; Marganne, Marie-Hélène ULg

Book published by CEDOPAL et Les Editions de l'Université de Liège (2006)

The monograph "The Villa of Papyri and the Herculaneum Scrolls. Philodemus' Library" by Daniel Delattre considers the origin, content – essentially epicurean philosophy – and the state of the most ... [more ▼]

The monograph "The Villa of Papyri and the Herculaneum Scrolls. Philodemus' Library" by Daniel Delattre considers the origin, content – essentially epicurean philosophy – and the state of the most beautiful private library that antiquity left us and the difficulties connected with deciphering scrolls charred by the eruption of Vesuvius in 79, and the most recent techniques – in particular multispectral imaging – developed to remedy this. Research director of the CNRS (Institut de Recherche et d'Histoire des Textes – papyrology section), Daniel Delattre has written several contributions on Herculanean papyrology and ancient philosophy, and is the editor of "Philodème de Gadara. Sur la musique, livre IV" in the Collection des Universités de France. [less ▲]

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See detailMaturation de Form@sup : principes et instrument
Poumay, Marianne ULg

in Revue Internationale de Pédagogie Universitaire (2006), 3(2), 1-17

Without resuming its detailed description, the present article proposes a critical analysis of the options taken in Form@sup, a one-year postgraduate degree for higher education teachers who want to ... [more ▼]

Without resuming its detailed description, the present article proposes a critical analysis of the options taken in Form@sup, a one-year postgraduate degree for higher education teachers who want to question their professional practice through the development of their online course. The article justifies the theoretical backgrounds of this training program and underlines the difficulties encountered in carrying out each of its basic principles. It then presents the decisions made for 2005-2006, insisting on the influence of the Scholarship of Teaching and Learning movement. Through its concrete examples, it also aims at fostering reflection and exchange of practice amongst the instructional developers teams. [less ▲]

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See detailAnalysis of kinetic energy release distributions by the maximum entropy method.
Leyh, Bernard ULg; Gridelet, E.; Locht, Robert ULg et al

in International Journal of Mass Spectrometry (2006), 249-250

Energy is not always fully randomized in an activated molecule because of the existence of dynamical constraints. An analysis of kinetic energy release distributions (KERDs) of dissociation fragments by ... [more ▼]

Energy is not always fully randomized in an activated molecule because of the existence of dynamical constraints. An analysis of kinetic energy release distributions (KERDs) of dissociation fragments by the maximum entropy method (MEM) provides information on the efficiency of the energy flow between the reaction coordinate and the remaining degrees of freedom during the fragmentation. For example, for barrierless cleavages, large translational energy releases are disfavoured while energy channeling into the rotational and vibrational degrees of freedom of the pair of fragments is increased with respect to a purely statistical partitioning. Hydrogen atom loss reactions provide an exception to this propensity rule. An ergodicity index, F, can be derived. It represents an upper bound to the ratio between two volumes of phase space: that effectively explored during the reaction and that in principle available at the internal energy E. The function F(E) has been found to initially decrease and to level off at high internal energies. For an atom loss reaction, the orbiting transition state version of phase space theory (OTST) is especially valid for low internal energies, low total angular momentum, large reduced mass of the pair of fragments, large rotational constant of the fragment ion, and large polarizability of the released atom. For barrierless dissociations, the major constraint that results from conservation of angular momentum is a propensity to confine the translational motion to a two-dimensional space. For high rotational quantum numbers, the influence of conservation of angular momentum cannot be separated from effects resulting from the curvature of the reaction path. The nonlinear relationship between the average translational energy <epsilon > and the internal energy E is determined by the density of vibrational-rotational states of the pair of fragments and also by non-statistical effects related to the incompleteness of phase space exploration. The MEM analysis of experimental KERDs suggests that many simple reactions can be described by the reaction path Hamiltonian (RPH) model and provides a criterion for the validity of this method. Chemically oriented problems can also be solved by this approach. A few examples are discussed: determination of branching ratios between competitive channels, reactions involving a reverse activation barrier, nonadiabatic mechanisms, and isolated state decay. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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