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See detailVariabilité des enregistrements polliniques en montagne et reconstitutions paléoécologiques.
David, F; Damblon, F; Farjanel, G et al

in Belgeo (2006), 3

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See detailInvasion intracellulaire des cellules non-phagocytaires par Staphylococcus aureus
Boulanger, Delphine; Bureau, Fabrice ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (2006), 150(1), 27-42

Intracellular invasion of Staphyloccocus aureus in nonphagocytic cells Staphylococcus aureus often causes chronic diseases. It is now believed that recurrence of these infections could be related to the ... [more ▼]

Intracellular invasion of Staphyloccocus aureus in nonphagocytic cells Staphylococcus aureus often causes chronic diseases. It is now believed that recurrence of these infections could be related to the ability of S. aureus to invade and persist within nonphagocytic cells. Adherence to eucaryotic cells is crucial for S. aureus to invade and persist within invasion and depends on interactions between bacterial fibronectin-binding proteins, fibronectin and the host cell fibronectin receptor, integrin alpha(5)beta(1). It is currently established that fibronectin acts as a bridging molecule. Penetration of S. aureus in host cells requires also activation of protein tyrosine kinases that mediate signal transduction and actin polymerization leading to cytoskeletal rearrangements. After internalization, S. aureus either remains in membrane-bound vacuoles or appears free in the cytoplasm. After bacterial proliferation, S. aureus induces host cell apoptosis or persist inside cells as small colony variants, which represent a less virulent subpopulation of S. aureus that grows slower. Although numerous in vitro and in vivo studies have demonstrated the ability of S. aureus to invade nonphagocytic cells, additional experiments have to be realized to understand the relevance of intracellular localization in vivo. [less ▲]

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See detailRésumé CEDH, 11 octobre 2005, NA et autres c. Turquie
Delnoy, Michel ULg

in Aménagement - Environnement (2006), 2

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See detailNifedipine nanocrystals: pharmacokinetic evaluation in the rat and permeability studies in Caco-2/HT29-5M21 (co)-cultures
Hecq, Julien; Nollevaux, Géraldine; Deleers, M. et al

in Journal of Drug Delivery Science and Technology (2006), 16(6, NOV-DEC), 437-442

Poorly water-soluble drugs such as nifedipine (NIF) (similar to 20 mu g/mL) offer challenging problems in drug formulation as poor solubility is generally associated with poor dissolution characteristics ... [more ▼]

Poorly water-soluble drugs such as nifedipine (NIF) (similar to 20 mu g/mL) offer challenging problems in drug formulation as poor solubility is generally associated with poor dissolution characteristics and thus with poor oral bioavailability (BCS class H drugs). In order to enhance these characteristics, formulation of NIF as nanocrystals was carried out. NIF nanoparticles (NP) were prepared using high-pressure homogenization (HPH). Solubility and dissolution characteristics have been reported in previous work to be significantly enhanced for NIF NP. Influence of NIF particle size on NIF permeation rate across intestinal cell models (Caco-2 and HT29-5M21 cultures and co-cultures) was investigated in order to complement these promising in vitro data. Apical to basolateral transfer studies were carried out across Caco-2 and HT29-5M21 cultures and co-cultures. Caco-2/HT29-5M21 co-cultures (seeding ratio 3: 1) were evaluated to better represent in vivo intestinal conditions. The influence of chitosan in the NIF NP formulation with regard to in vitro NIF permeation rate was also evaluated. These studies showed that NIF permeation rate across the different in vitro models evaluated can be significantly enhanced (approximate to 6-fold) by formulation of NIF as nanoparticles. No significant difference was observed either in the presence of chitosan in the formulation or between the three cell models evaluated. To complement these observations, preliminary in vivo pharmacokinetic evaluations in Sprague-Dawley rats, in the fed and fasted states, were also carried out for both un-milled NIF and NIF NP. [less ▲]

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See detailSurvival in the cold: proteome analysis of the psychrophilic marine bacterium Pseudoalteromonas haloplanktis TAC125
Wilmes, B.; Glagla, S.; Albrecht, D. et al

Poster (2006)

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See detailNew validation strategy for the LC determination of ascorbic acid in sublingual tablets
Cahay, B.; Rousseau, Anne ULg; Klinkenberg, R. et al

Poster (2006)

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See detailEffect of parental socio-educational level on memory and attentional measures in children
Catale, Corinne ULg; Hogge, Michaël; Meulemans, Thierry ULg

in Book of Abstracts: Annual Meeting of the Belgian Association for Psychological Science (2006)

In developmental neuropsychology, information about the influence of educational variables on executive and memory development is limited. This is particularly surprising when considering the adult ... [more ▼]

In developmental neuropsychology, information about the influence of educational variables on executive and memory development is limited. This is particularly surprising when considering the adult literature regarding the social and cultural effects on cognitive performances, which provide evidence that groups with higher levels of education achieve better on most neuropsychological tests (Ostrosky, Ardila, & Rosselli, 1999). The aim of this study was to analyze the relation between parents’ educational level and executive, attentional, memory and intellectual measures. Memory tasks (working and episodic memory), executive (inhibition and switching), attentional (alertness and selective attentional task) and intellectual tasks (verbal and non verbal subtests of WISC-III) were individually administered to 96 children divided according to 2 variables: age (6 and 10 years old) and parent’s educational level (University, High School and Elementary Education). Results showed an expected significant association between age and performance on all cognitive tasks. There was also a significant effect of parents’ educational level on most verbal tasks performed by children (including memory and verbal intellectual subtests) but also on various executive and attentional tasks (alertness, switching and inhibition tasks). Results confirmed that educational variables significantly influence children cognitive performances and not for only intelligence and verbal tasks, and emphasizes the need of further studies to specify the influence of education on the development of cognition. [less ▲]

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See detailStudy of precursors responsible for off-flavor formation during storage of potato flakes.
Laine, G.; Göbel, Cornelia; du Jardin, Patrick ULg et al

in Journal of Agricultural and Food Chemistry (2006), 54

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See detailAnalytic properties of unitarization schemes
Selyugin, Oleg Viktorovich; Cudell, Jean-René ULg

in Czechoslovak Journal of Physics (2006)

The analytic properties of the elastic hadron scattering amplitude are examined in the impact parameter representation at high energies. Different unitarization procedures and the corresponding non-linear ... [more ▼]

The analytic properties of the elastic hadron scattering amplitude are examined in the impact parameter representation at high energies. Different unitarization procedures and the corresponding non-linear equations are presented. Several unitarisation schemes are presented. They lead to almost identical results at the LHC. [less ▲]

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See detailA model reduction method for the control of rigid mechanisms
Bruls, Olivier ULg; Duysinx, Pierre ULg; Golinval, Jean-Claude ULg

in Multibody System Dynamics (2006), 15(3), 213-227

This paper presents a reduction method to build closed-form dynamic equations for rigid multibody systems with a minimal kinematic description. Relying on an initial parameterization with absolute ... [more ▼]

This paper presents a reduction method to build closed-form dynamic equations for rigid multibody systems with a minimal kinematic description. Relying on an initial parameterization with absolute displacements and rotations, the method is able to tackle complex topologies with closed-loops in a systematic way and its extension to flexible multibody systems will be investigated in the future. Thus, it would be of great use in the framework of model-based control of mechanisms. The method is based on an interpolation strategy. The initial model is built and reduced for a number of selected points in the configuration space. Then, a piecewise polynomial model is adjusted to match the collected data. After the presentation of the reduction procedure and of the interpolation strategy, two applications of the reduction method are considered: a four-bar mechanism and a parallel kinematic machine-tool called "Orthoglide". [less ▲]

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See detailIdentification of yield locus parameters of metals using inverse modeling and full field DIC
Lecompte, D.; Cooreman, S.; Sol, H. et al

in Proceedings of the 7th national congress on theoretical and applied mechanics (2006)

The basic principle of the inverse modeling procedure as it is used for parameter identification is the generation of a complex and heterogeneous deformation field that contains as much information as ... [more ▼]

The basic principle of the inverse modeling procedure as it is used for parameter identification is the generation of a complex and heterogeneous deformation field that contains as much information as possible about the parameters to be identified. One way of obtaining such a non-homogeneous deformation is by making the geometry of the specimen less regular. Another possibility is to make the loading conditions more complex. In this paper both options are actually combined by using the concept of a biaxial tensile test on a perforated cruciform specimen. In the present paper, the work hardening of the material is assumed to be isotropic and it is described by a Swift law. The yield locus is modeled by the anisotropic Hill48 criterion. The optimization technique used is a constrained gradient based Newton-type routine, which means that in every iteration step, a sensitivity calculation has to be performed in order to indicate the direction in which the parameters are to be optimized. The functional to be minimized is a least-squares expression of the discrepancy between the measured and the simulated strain fields at a certain load. The numerical routines as well as the identification results of the different parameters, based on simulated strain fields, are discussed. [less ▲]

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See detailTabagisme occasionnel de l'adolescent, ou commence la nocivite?
Bartsch, Pierre ULg; Laperche, J.

in Revue Médicale de Liège (2006), 61(5-6, May-Jun), 394-400

It is clear that even low rate smoking is hazardous for health, the risk being independently increased by the daily number of cigarettes smoked and by the duration of smoking. The question raised is thus ... [more ▼]

It is clear that even low rate smoking is hazardous for health, the risk being independently increased by the daily number of cigarettes smoked and by the duration of smoking. The question raised is thus: will an adolescent experimenter be a non smoker, an experimenter for ever, a regular smoker, light or heavy? This short review shows that there are numerous factors from genetics, to familial environment not limited to tobacco issues, smoking situation at school as well as school performances of the student, and also individual psychological characteristics. The experimenter is a very good target for smoking cessation actions and should deserve particular attention from preventive medicine and, thus, from school medicine, before he becomes a regular smoker, who will be more resistant to smoking cessation programs. [less ▲]

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See detailMovement patterns, spatial distribution and depth preference by individual whitefish, Coregonus lavaretus in a small artificial lake
Ovidio, Michaël ULg; Neus, Yvan ULg; Rimbaud, Gilles ULg et al

in Folia Zoologica (2006), 55(4), 375-385

Using manual acoustic tracking our study quantified (1) the spatial distribution (2) the movement patterns and (3) the depth preference of adult whitefish, Coregonus lavaretus in it small artificial lake ... [more ▼]

Using manual acoustic tracking our study quantified (1) the spatial distribution (2) the movement patterns and (3) the depth preference of adult whitefish, Coregonus lavaretus in it small artificial lake of eastern Belgium were the species was introduced in 1978 for recreational fishing. From June to October 2004, n=6 C. lavaretus (LF 285-519 mm) were tracked (pingers and depth sensor transmitters) from a small boat over periods ranging from 98 to 108 days in Robertville Lake (elevation: 490 m; area: 63 ha max. depth: 47 in). Whitefish were consistently mobile but showed quite variable lake use patterns. Two individuals traveled the entire length and breadth of the lake, whereas others remained in movement in the deep zone in the middle part of the lake or near the retaining darn wall. Whitefish occupied positions in the water column ranging front 2.6 to 27.0 m (mean 12.7 +/- 5.6 m) that varied depending on individuals. This first study on individual whitefish behaviour provides a better understanding of the behavioural ecology of the species in small artificial lake. [less ▲]

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See detailA structural, infrared, and Mossbauer spectral study of rosemaryite, NaMnFe3+Al(PO4)(3)
Hatert, Frédéric ULg; Hermann, R. P.; Fransolet, André-Mathieu ULg et al

in European Journal of Mineralogy (2006), 18(6, NOV-DEC), 775-785

Rosemaryite, ideally NaMnFe(3+)AI(PO4)(3), has been collected in the Buranga pegmatite, Rwanda. A single-crystal structure refinement was performed to R-1 = 4.01 %, in the P2(1)/n space group, with a = 12 ... [more ▼]

Rosemaryite, ideally NaMnFe(3+)AI(PO4)(3), has been collected in the Buranga pegmatite, Rwanda. A single-crystal structure refinement was performed to R-1 = 4.01 %, in the P2(1)/n space group, with a = 12.001(2), b = 12.396(1), c = 6.329(1) angstrom, beta 114.48(1)degrees, Vol. = 856.9(2) angstrom(3), Z = 4. The crystal structure and cation distributions are similar to those of ferrorosemaryite, NaFe2+Fe3+Al(PO4)(3), and qingheiite, Na2MnMgAl(PO4)(3), but aluminium predominantly occurs in the M(2a) site, not in the M(2b) site as observed in ferrowyllieite, Na2Fe22+Al(PO4)(3). The topologies of the X(1a) and X(1b) crystallographic sites are identical to those found in ferrorosemaryite, and correspond to a distorted octahedron and to a distorted cube, respectively. The [7+1]-coordinated X(2) site is a very distorted gable disphenoid, similar to the A(2)' site of the alluaudite structure. Mossbauer spectra have been obtained from 4.2 to 295 K, and fitted with a model including two Fe3+ and two Fe2+ doublets. The Fe2+ component corresponding to 2/3 of the Fe2+ spectral area and having a smaller quadrupole splitting of 2.63 mm/s at 15 K, is assigned to the Fe2+ on the M(2a) site, and the Fe2+ component with the larger quadrupole splitting of 3.17 mm/s at 15 K, is assigned to the Fe2+ on the M(1) site. Fe3+ is located only at the M(2a) and M(2b) sites, and the Fe3+ component corresponding to 3/4 of the Fe3+ and exhibiting the larger quadrupole spitting of 0.77 mm/s at 15 K, is most likely associated with Fe3+ on the M(2b) site. The infrared spectrum of rosemaryite shows absorption bands at 3450 and 1624 cm(-1), bands that arise from the vibrational modes of H2O and confirm the presence of water in the channels of the wyllieite structure. A comparison of both the Mossbauer spectra and structural data of rosemaryite with those of other phosphates of the alluaudite and wyllieite groups, is also presented. [less ▲]

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See detailValidation of a potentiometric method using azithromycin selective electrode
Rachidi, Mohamed ULg; Cherra, Y.; Digua, K. et al

Poster (2006)

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See detailImagerie médicale - bases physiques
Seret, Alain ULg; Hoebeke, Maryse ULg

Book published by Editions de l'Université de Liège (2006)

The book explains the physical foundations of the most common in-vivo medical imaging modalities. It is written for readers having a basic knowledge of physics. However the most essential physical ... [more ▼]

The book explains the physical foundations of the most common in-vivo medical imaging modalities. It is written for readers having a basic knowledge of physics. However the most essential physical phenomenon and their properties are described. Exploring the electromagnetic spectrum from the shortest to the longest wavelengths the book deals with nuclear imaging, RX imaging, endoscopy, thermography and MRI. Acoustic wave and ultrasonography is the next subject. The book ends with the digital image and a few radioprotection notions. [less ▲]

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See detailQuantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE).
Asquith, Becca; Debacq, Christophe; Florins, Arnaud-Francois ULg et al

in Proceedings of the Royal Society B : Biological Sciences (2006), 273(1590), 1165-71

The cytoplasmic dye carboxyfluorescein diacetate succinimidyl ester (CFSE) is used to quantify cell kinetics. It is particularly important in studies of lymphocyte homeostasis where its labelling of cells ... [more ▼]

The cytoplasmic dye carboxyfluorescein diacetate succinimidyl ester (CFSE) is used to quantify cell kinetics. It is particularly important in studies of lymphocyte homeostasis where its labelling of cells irrespective of their stage in the cell cycle makes it preferable to deuterated glucose and BrdU, which only label dividing cells and thus produce unrepresentative results. In the past, experiments have been limited by the need to obtain a clear separation of CFSE peaks forcing scientists to adopt a strategy of in vitro labelling of cells followed by their injection into the host. Here we develop a framework for analysis of in vivo CFSE labelling data. This enables us to estimate the rate of proliferation and death of lymphocytes in situ, and thus represents a considerable advance over current procedures. We illustrate this approach using in vivo CFSE labelling of B lymphocytes in sheep. [less ▲]

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See detailRenaissance de l’Égypte aux Temps Modernes. De l’intérêt pour la civilisation pharaonique et ses hiéroglyphes à Liège au XVIe siècle
Laboury, Dimitri ULg

in Warmenbol, Eugène (Ed.) La Caravane du Caire. L’Égypte sur d’autres rives (2006)

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See detailInfluence of coal characteristics on laser-induced plasmas
Chen, Wen; Lu, Jidong; Yu, Liangying et al

in Journal of Applied Optics (2006), 27(3), 216-219

Eight kinds of typical coal samples were chosen for studying the influence of coal characteristics on laser—induced plasmas.Element analysis and industry analysis were carried out for every ... [more ▼]

Eight kinds of typical coal samples were chosen for studying the influence of coal characteristics on laser—induced plasmas.Element analysis and industry analysis were carried out for every sample.Experimental study on the interaction between laser and different coal samples was completed,and factors affecting laser plasma were analyzed,such as coal moisture and coal dust.The experiment result indicates that the coal samples with different coalification degrees have different plasma time—resolved spectral characteristics,all of them tend to rise at the beginning of plasma formation (< 1us),then with the decay of plasmas emission.they tend to decrease in about 1us,while secondary ionization occurs in highly coalificated coals after 2 us.The plasma temperature differs from one kind to another,the higher the coalification degree is,the higher the plasma temperature will be. [less ▲]

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