La Cartographie des Zones Inondées : Approche géomorphologique et Enquêtes de Terrain
Peeters, Alexandre ; Van Campenhout, Jean ; et al
in Les risques majeurs en Région wallonne : prévenir en aménageant (2006)Detailed reference viewed: 95 (33 ULg)
L'oral au quotidien : pistes de réflexion et d'action pour l'enseignement du langage oral au cycle 2 ans 1/2 à 5 ans.
Book published by Centre technique et pédagogique de la Communauté française (2006)Detailed reference viewed: 71 (8 ULg)
Rapport des activités réalisées par le Centre Agronomique et Vétérinaire Tropical de Kinshasa dans le secteur de la volaille.
Bindelle, Jérôme ; ; et al
Report (2006)Detailed reference viewed: 36 (5 ULg)
Locomotor effects of ethanol and acetaldehyde after peripheral and intraventricular injections in Swiss and C57BL/6J mice
Tambour, Sophie ; Didone, Vincent ; Tirelli, Ezio et al
in Behavioural Brain Research (2006), 172(1), 145-154
Several studies have suggested that acetaldehyde, the first product of ethanol metabolism, is involved in the locomotor stimulant effects of ethanol in mice, although it has never been formally tested ... [more ▼]
Several studies have suggested that acetaldehyde, the first product of ethanol metabolism, is involved in the locomotor stimulant effects of ethanol in mice, although it has never been formally tested whether acetaldehyde injected directly into the brain of mice has stimulant properties. Recently, it was also shown in rats that both ethanol and acetaldehyde can induce opposite locomotor effects according to the route of administration. Whereas peripheral administrations of ethanol and acetaldehyde induced locomotor depressant effects, their infusions directly into the brain produced locomotor stimulation. The aim of the present study was to characterize in mice the locomotor effects of ethanol and acetaldehyde injected either peripherally by the intraperitoneal route or centrally into the brain ventricles. Additionally, the effects of ethanol and acetaldehyde were compared in two strains of mice known for their differential sensitivity to the locomotor effects of ethanol, namely Swiss and C57BL/6J mice. Ethanol induced a biphasic effect on locomotor activity in Swiss mice, with stimulant effects at low to moderate doses and depressant effects at higher doses. Such a profile of effects was observed whatever the route of administration, peripheral or central. In C57BL/6J mice, ethanol only induced monophasic depressant effects. In this mouse strain, no evidence of the stimulant effects of ethanol was found after either an i.p. or an i.c.v. administration of ethanol. In contrast to ethanol, acetaldehyde yielded only depressant effects in both strains of mice after both peripheral and central administrations. These results indicate that the route of administration does not alter the locomotor effects of ethanol and acetaldehyde in mice. Additionally, the present study shows that the stimulant properties of acetaldehyde, even after direct infusion into the brain, are not as obvious as previously speculated. [less ▲]Detailed reference viewed: 157 (4 ULg)
Effets symptomatiques de la glucosamine dans l’arthrose. Que retenir des nouvelles études européenne (GUIDE) et nord-américaine (GAIT) ?
Reginster, Jean-Yves ; Bruyère, Olivier
in Medi-Sphere (2006), 271Detailed reference viewed: 31 (10 ULg)
Etude de l'implication potentielle de l'acétaldéhyde dans les effets comportementaux aigus de l'alcool chez la souris
Doctoral thesis (2006)Detailed reference viewed: 54 (15 ULg)
The Copula construction in Old and Middle English: On the interaction between constructions and lexicon
Petré, Peter ;
Conference (2006)Detailed reference viewed: 8 (1 ULg)
Waimes/Robertville: la Via Mansuerisca et la découverte d'un véhicule
; Hoffsummer, Patrick
in Vie archéologique, chronique de l'archéologie wallonne (2006), 13Detailed reference viewed: 125 (5 ULg)
Suppression of limit cycle oscillations with a nonlinear energy sink: experimental results
; ; et al
in 47th AIAA Structural Dynamics and Materials Conference, Newport, 2006 (2006)
The presence of limit cycle oscillations within the flight envelopes of existing aircraft is well documented. Future air vehicle designs are also likely to encounter limit cycle oscillations under certain ... [more ▼]
The presence of limit cycle oscillations within the flight envelopes of existing aircraft is well documented. Future air vehicle designs are also likely to encounter limit cycle oscillations under certain loading conditions. These steady-state constant amplitude oscillations are detrimental to mission effectiveness and lead to increased fatigue of aircraft structures. Previous efforts to suppress limit cycle oscillations have focused primarily on active control methods. These efforts have been effective but require significant measurement and control resources. In this study the investigators test a passive method for suppressing limit cycle behavior. A nonlinear energy sink, based on the principle of nonlinear energy pumping, is shown to be effective for increasing the stability threshold of a nonlinear two degree of freedom aeroelastic system. [less ▲]Detailed reference viewed: 57 (3 ULg)
Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: assessment of uncertainty.
Marini Djang'Eing'A, Roland ; ; et al
in Electrophoresis (2006), 27(12), 2386-99
Analyses of statistical variance were applied to evaluate the precision and practicality of a CD-based NACE assay for R-timolol after enantiomeric separation of R- and S-timolol. Data were collected in an ... [more ▼]
Analyses of statistical variance were applied to evaluate the precision and practicality of a CD-based NACE assay for R-timolol after enantiomeric separation of R- and S-timolol. Data were collected in an interlaboratory study by 11 participating laboratories located in Europe and North America. General qualitative method performance was examined using suitability descriptors (i.e. resolution, selectivity, migration times and S/N), while precision was determined by quantification of variances in the determination of R-timolol at four different impurity levels in S-timolol maleate samples. The interlaboratory trials were designed in accordance with the ISO guideline 5725-2. This allowed estimating for each sample, the different variances, i.e. between-laboratory (s2(Laboratories)), between-day (s2(Days)) and between-replicate (s2(Replicates)). The variances of repeatability (s2r) and reproducibility (s2R) were then calculated. The estimated uncertainty, derived from the precision estimates, seems to be concentration-dependent above a given threshold. This example of R-timolol illustrates how a laboratory can evaluate uncertainty in general. [less ▲]Detailed reference viewed: 59 (12 ULg)
Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: what's wrong with these enzymes?
; Charlier, Paulette ; et al
in Biochemistry (2006), 45(51), 15873-83
Beta-lactams exert their antibiotic action through their inhibition of bacterial DD-peptidases (penicillin-binding proteins). Bacteria, in general, carry several such enzymes localized on the outside of ... [more ▼]
Beta-lactams exert their antibiotic action through their inhibition of bacterial DD-peptidases (penicillin-binding proteins). Bacteria, in general, carry several such enzymes localized on the outside of their cell membrane to catalyze the final step in cell wall (peptidoglycan) synthesis. They have been classified into two major groups, one of high molecular weight, the other of low. Members of the former group act as transpeptidases in vivo, and their inhibition by beta-lactams leads to cessation of bacterial growth. The latter group consists of DD-carboxypeptidases, and their inhibition by beta-lactams is generally not fatal to bacteria. We have previously shown that representatives of the former group are ineffective at catalyzing the hydrolysis/aminolysis of peptidoglycan-mimetic peptides in vitro [Anderson et al. (2003) Biochem. J. 373, 949-955]. The theme of these experiments is expanded in the present paper where we describe the synthesis of a series of beta-lactams (penicillins and cephalosporins) containing peptidoglycan-mimetic side chains and the kinetics of their inhibition of a panel of penicillin-binding proteins spanning the major classes (Escherichia coli PBP 2 and PBP 5, Streptococcus pneumoniae PBP 1b, PBP 2x and PBP 3, the Actinomadura R39 DD-peptidase, and the Streptomyces R61 DD-peptidase). The results of these experiments mirror and expand the previous results with peptides. Neither peptides nor beta-lactams with appropriate peptidoglycan-mimetic side chains react with the solubilized constructs of membrane-bound penicillin binding proteins (the first five enzymes above) at rates exceeding those of generic analogues. Such peptides and beta-lactams do react at greatly enhanced rates with certain soluble low molecular weight enzymes (R61 and R39 DD-peptidases). The former result is unexpected and interesting. Why do the majority of penicillin-binding proteins not recognize elements of local peptidoglycan structure? Possible answers are discussed. That this question needs to be asked casts fascinating shadows on current studies of penicillin-binding proteins for new drug design. [less ▲]Detailed reference viewed: 36 (6 ULg)
The Evolution of Organizational and Management Models in courts: the emergence of a new paradigm?
Conference (2006)Detailed reference viewed: 8 (0 ULg)
Facteurs influençant l'efficacité des repeuplements. In: Vers une nouvelle politique des rempoissonnements.
; Poncin, Pascal
in Vers une nouvelle politique de rempoissonnement (2006)Detailed reference viewed: 24 (5 ULg)
Les "Ménines" de Vélasquez : une posture didactique
in Cramer, Evelyn; Ricker, Marie-Emilie; Souveryns, Patrick (Eds.) Didactiques de l'histoire et de l'histoire de l'art : divergences, convergences et complémentarités. 3e Journée interuniversitaire des Didactiques d'Histoire de l'Art (2006)Detailed reference viewed: 58 (10 ULg)
Eukaryotic organisms in Proterozoic oceans
; Javaux, Emmanuelle ; et al
in Philosophical Transactions : Biological Sciences (2006), 361(1470), 1023-1038
The geological record of protists begins well before the Ediacaran and Cambrian diversification of animals, but the antiquity of that history, its reliability as a chronicle of evolution and the causal ... [more ▼]
The geological record of protists begins well before the Ediacaran and Cambrian diversification of animals, but the antiquity of that history, its reliability as a chronicle of evolution and the causal inferences that can be drawn from it remain subjects of debate. Well-preserved protists are known from a relatively small number of Proterozoic formations, but taphonomic considerations suggest that they capture at least broad aspects of early eukaryotic evolution. A modest diversity of problematic, possibly stem group protists occurs in ca 1800-1300 Myr old rocks. 1300-720 Myr fossils document the divergence of major eukaryotic clades, but only with the Ediacaran-Cambrian radiation of animals did diversity increase within most clades with fossilizable members. While taxonomic placement of many Proterozoic eukaryotes may be arguable, the presence of characters used for that placement is not. Focus on character evolution permits inferences about the innovations in cell biology and development that underpin the taxonomic and morphological diversification of eukaryotic organisms. [less ▲]Detailed reference viewed: 12 (1 ULg)