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See detailActes du colloque - le coton dans tous ses etats, Gembloux (Belgique), 12 mai 2006.
Thewis, André ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2006), 10(4), 267

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See detailControl of floral transition in maize
Van Kerkhoven, Fabrizio ULg; Jennès, Nicolas; Périlleux, Claire ULg

in Comparative Biochemistry & Physiology Part A : Molecular & Integrative Physiology (2006), 143(4), 170

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See detailALADDIN: an optimized ground-based precursor for DARWIN
Coudé du Foresto, Vincent; Absil, Olivier ULg; Barillot, Marc et al

in Aime, C.; Vakili, F. (Eds.) Direct Imaging of Exoplanets: Science & Techniques (2006)

The ALADDIN concept is an integrated Antarctic-based L-band experiment whose purpose is to demonstrate nulling interferometry and to prepare the DARWIN mission. Because of their privileged location, the ... [more ▼]

The ALADDIN concept is an integrated Antarctic-based L-band experiment whose purpose is to demonstrate nulling interferometry and to prepare the DARWIN mission. Because of their privileged location, the relatively modest collectors (1 m) and baseline (up to 40 m) are sufficient to achieve a sensitivity (in terms of detectable zodi levels) which is about twice better than that of a nulling instrument on a large interferometer (such as GENIE at the VLTI), and to reach the 20-zodi threshold value identified to carry out the DARWIN precursor science. These numbers are based on a preliminary design study by Alcatel Alenia Space and were obtained using the same simulation software as the one employed for GENIE. The integrated design enables top-level optimization and full access to the light collectors for the duration of the experiment, while reducing the complexity of the nulling breadboard. [less ▲]

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See detailTexturation of YBa2Cu3O7-delta thick films by electrophoretic deposition under magnetic field
Dusoulier, Laurent; Denis, Samuel ULg; Nutal, Nicolas ULg et al

in Key Engineering Materials [=KEM] (2006), 314

YBa2Cu3O7-delta coatings were deposited by electrophoretic deposition (EPD) onto Ni substrates. Particles of different sizes and shapes were used in order to study the influence of the powder ... [more ▼]

YBa2Cu3O7-delta coatings were deposited by electrophoretic deposition (EPD) onto Ni substrates. Particles of different sizes and shapes were used in order to study the influence of the powder microstructure on the film density. Texturation of the thick films was induced by application of a magnetic field during the electrophoretic deposition. X-ray diffraction analysis has clearly shown preferred c-axis alignment of the YBa2Cu3O7-delta films along the direction normal to the substrate surface. Scanning electron microscopy and optical polarised light microscopy were used to characterise the microstructure of the coatings, revealing a nonrandom platelets organisation. [less ▲]

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See detailFour-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
Cruyssen, B. V.; Van Looy, S.; Wyns, B. et al

in Arthritis Research & Therapy (2006), 8(4), 112

Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-alpha agents, few studies have examined the long-term effects. We evaluated 511 patients with ... [more ▼]

Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-alpha agents, few studies have examined the long-term effects. We evaluated 511 patients with long-standing refractory rheumatoid arthritis treated with intravenous infusions of infliximab 3 mg/kg at weeks 0, 2, 6, and 14 and every 8 weeks thereafter for 4 years. Among the initial 511 patients included in the study, 479 could be evaluated; of these, 295 (61.6%) were still receiving infliximab treatment at year 4 of follow-up. The most common reasons for treatment discontinuation were lack of efficacy (65 patients, 13.6%), safety (81 patients, 16.9%), and elective change (38 patients, 7.9%). Analysis of disease activity scores (DAS28 [ disease activity score based on the 28-joint count]) over time showed that, after the initial rapid improvement during the first 6 to 22 weeks of therapy, a further decrease in disease activity of 0.2 units in the DAS28 score per year was observed. DAS28 scores, measured at week 14 or 22, were found to predict subsequent discontinuation due to lack of efficacy. In conclusion, long-term maintenance therapy with infliximab 3 mg/kg is effective in producing further reductions in disease activity. Disease activity measured by the DAS28 at week 14 or 22 of infliximab therapy was the best predictor of long-term attrition. [less ▲]

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See detailp27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.
Nguyen, Laurent ULg; Besson, Arnaud; Heng, Julian Ik-Tsen et al

in Genes & Development (2006), 20(11), 1511-24

The generation of neurons by progenitor cells involves the tight coordination of multiple cellular activities, including cell cycle exit, initiation of neuronal differentiation, and cell migration. The ... [more ▼]

The generation of neurons by progenitor cells involves the tight coordination of multiple cellular activities, including cell cycle exit, initiation of neuronal differentiation, and cell migration. The mechanisms that integrate these different events into a coherent developmental program are not well understood. Here we show that the cyclin-dependent kinase inhibitor p27(Kip1) plays an important role in neurogenesis in the mouse cerebral cortex by promoting the differentiation and radial migration of cortical projection neurons. Importantly, these two functions of p27(Kip1) involve distinct activities, which are independent of its role in cell cycle regulation. p27(Kip1) promotes neuronal differentiation by stabilizing Neurogenin2 protein, an activity carried by the N-terminal half of the protein. p27(Kip1) promotes neuronal migration by blocking RhoA signaling, an activity that resides in its C-terminal half. Thus, p27(Kip1) plays a key role in cortical development, acting as a modular protein that independently regulates and couples multiple cellular pathways contributing to neurogenesis. [less ▲]

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See detailAdvanced exploitation of ground-based Fourier transform infrared observations for tropospheric studies over Europe: achievements of the UFTIR project
De Mazière, Martine; Vigouroux, Corinne; Blumenstock, Thomas et al

in Geophysical Research Abstracts (2006), 8

Solar absorption measurements using Fourier transform infrared (FTIR) spectrometry carry information about the atmospheric abundances of many constituents, including information about their vertical ... [more ▼]

Solar absorption measurements using Fourier transform infrared (FTIR) spectrometry carry information about the atmospheric abundances of many constituents, including information about their vertical distributions in the troposphere and the stratosphere. Such observations have regularly been made since many years as a contribution to the NDSC (Network for the Detection of Stratospheric Change). They are the only ground-based remote sensing observations available nowadays that carry information about key atmospheric trace species in the free troposphere, among which the most important greenhouse gases. The European UFTIR project (Time series of Upper Free Troposphere observations from a European ground-based FTIR network, http://www.nilu.no/uftir) has focused on maximizing the information content of FTIR long-term monitoring data of some direct and indirect greenhouse gases (CH4, N2O, O3,HCFC-22, and CO and C2H6, respectively). The UFTIR network includes six NDSC stations in Western Europe, covering the polar to subtropical regions. At several stations of the network, the observations span more than a decade. Existing spectral time series have been reanalyzed according to a common optimized retrieval strategy, in order to derive distinct tropospheric and stratospheric abundances of the abovementioned target gases. A bootstrap resampling method has been implemented to evaluate trends of the tropospheric and total burdens of the target gases, including their uncertainties. In parallel, simulations of the target time series have been made with the Oslo CTM2 model: comparisons between the model results and the observations provide valuable information to improve the model, and in particular, to optimize emission estimates that are used as inputs to the model simulations, and to explain the observed trends. The final results of the project will be presented, and ways to proceed will be discussed. [less ▲]

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See detailRapid changes in production and behavioral action of estrogens.
Balthazart, Jacques ULg; Cornil, Charlotte ULg; Taziaux, Mélanie ULg et al

in Neuroscience (2006), 138(3), 783-91

It is well established that sex steroid hormones bind to nuclear receptors, which then act as transcription factors to control brain sexual differentiation and the activation of sexual behaviors ... [more ▼]

It is well established that sex steroid hormones bind to nuclear receptors, which then act as transcription factors to control brain sexual differentiation and the activation of sexual behaviors. Estrogens locally produced in the brain exert their behavioral effects in this way but mounting evidence indicates that estrogens also can influence brain functioning more rapidly via non-genomic mechanisms. We recently reported that, in Japanese quail, the activity of preoptic estrogen synthase (aromatase) can be modulated quite rapidly (within minutes) by non-genomic mechanisms, including calcium-dependent phosphorylations. Behavioral studies further demonstrated that rapid changes in estrogen bioavailability, resulting either from a single injection of a high dose of estradiol or from the acute inhibition of aromatase activity, significantly affect the expression of both appetitive and consummatory aspects of male sexual behavior with latencies ranging between 15 and 30 min. Together these data indicate that the bioavailability of estrogens in the brain can change on different time-scales (long- and short-term) that match well with the genomic and non-genomic actions of this steroid and underlie two complementary mechanisms through which estrogens modulate behavior. Estrogens produced locally in the brain should therefore be considered not only as neuroactive steroids but they also display many (if not all) functional characteristics of neuromodulators and perhaps neurotransmitters. [less ▲]

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See detailCaryl Phillips's Drama: A Blueprint for a New Britishness?
Ledent, Bénédicte ULg

in Davis, Geoffrey V.; Fuchs, Anne (Eds.) Staging New Britain: Aspects of Black and South Asian British Theatre Practice (2006)

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See detailA framework for an optimised groundwater monitoring network and aggregated indicators
Rentier, Céline; Delloye, Francis; Brouyère, Serge ULg et al

in Environmental Geology (2006), 50(2), 194-201

The implementation of the Water Framework Directive (EU 2000) requires a groundwater quality monitoring. It is used for characterisation of the 'good' chemical status of each groundwater body and for the ... [more ▼]

The implementation of the Water Framework Directive (EU 2000) requires a groundwater quality monitoring. It is used for characterisation of the 'good' chemical status of each groundwater body and for the restoration or protection purposes of those bodies already at 'good' status. Interpretative aspects are lying in the design of monitoring network and in the way of building global indicators. Attention is given here to the global chemical status of the groundwater bodies and to the role of diffuse pollution, much of which is brought via groundwater to surface water. Monitoring 'local' pollution associated with individual sites is not addressed. Groundwater bodies with different contrasted hydrogeology conditions, land use and topography have been considered to establish an approach for choosing an optimised monitoring network. Then, a quality assessment system has been developed and applied for qualifying the general status of each groundwater body. The use of non-dimensional indexes allows us to process with all kinds of chemical parameters in a normalised way and, by means of adequate aggregation rules, to qualify the general quality status of a groundwater body. The obtained diagnostic, even if not fully validated, is closely linked to the pragmatic objectives contained in the EU Water Directive. [less ▲]

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See detailSulphides and selenides from thrust-slice 2400, Musonoï Mine, Katanga, Congo
Pirard, Cassian; Hatert, Frédéric ULg

Conference (2006)

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See detailSynthesis and pharmacological evaluation of some N-arylsulfonyl-N-methyl-N'-(2,2-dimethyl-2-H-1-benzopyran-4-yl)ureas structurally related to cromakalim
Khelili, S.; Lebrun, P.; De Tullio, Pascal ULg et al

in Bioorganic & Medicinal Chemistry (2006), 14

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See detailDie Dämonie von Verlassenheit und Fremde in den Erzählungen Stefan Zweigs. Abstract
Küpper, Achim ULg

in Stefan Zweig und das Dämonische: Abstracts (2006)

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See detailMagnetic resonance imaging of canine elbow joint
Saunders; Snaps, Frédéric ULg

Conference (2006)

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See detailEquivariant quantizations and Cartan connections
Mathonet, Pierre ULg

in Bulletin of the Belgian Mathematical Society Simon Stevin (2006), 13(5), 857-874

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See detailRevision of the Belgian Nursing Minimum Dataset: from data to information
SERMEUS, Walter; VAN DEN HEEDE, Koen; MICHIELS, Dominik et al

in Studies in Health Technology & Informatics (2006), 122

The Ministry of Public Health commissioned a research project to the Catholic University of Leuven and the University Hospital of Liege to revise the Belgian Nursing Minimum Dataset (B-NMDS). The study ... [more ▼]

The Ministry of Public Health commissioned a research project to the Catholic University of Leuven and the University Hospital of Liege to revise the Belgian Nursing Minimum Dataset (B-NMDS). The study started in 2000 and will end with the implementation of the revised B-NMDS in January 2007. The study entailed four major phases. The first phase involved the development of a conceptual framework based on a literature review and secondary data analysis. The second phase focused on language development and development of a data collection tool. The third phase focused on data collection and validation of the new tool. In the fourth phase the validity and reliability of the dataset was tested. The new dataset is without avail if it is not leading to new information. Four applications of the dataset has been defined from the beginning: evaluation of the appropriateness of stay (AEP) in the hospital, nurse staffing, hospital financing and quality management. The aim of this paper is to describe how the B-NMDS can contribute to each of these applications. [less ▲]

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See detailImproved vitrification method allowing direct transfer of goat embryos
Guignot, F.; Bouttier, A.; Baril, G. et al

in Theriogenology (2006), 66(4), 1004-1011

The aim of this study was to design a vitrification method suited to field embryo transfer experiments in goat. In a first experiment, a standard vitrification protocol, previously designed for sheep ... [more ▼]

The aim of this study was to design a vitrification method suited to field embryo transfer experiments in goat. In a first experiment, a standard vitrification protocol, previously designed for sheep embryos was compared to slow freezing of goat embryos. No significant difference was observed on kidding rate (48% versus 69%, respectively), nor on embryo survival rate (35% versus 45%). Second experiment: all embryos were vitrified. After warming, embryos were either transferred directly (direct transfer), or after in vitro dilution of the cryoprotectants (conventional transfer). The kidding rate was not affected by the transfer method (38% versus 23%, respectively). However, embryo survival rate tended to be higher after direct transfer (26% versus 14%). Third experiment: OPS vitrification was compared to standard vitrification. The kidding rate was not affected (22% versus 39%, respectively), but the embryo survival rate was lower after OPS (14% versus 28%). Fourth experiment: 0.4 M sucrose was added with cryoprotectants in vitrification. The kidding rate after direct transfer was significantly enhanced after addition of sucrose (56% versus 27%, respectively), whereas embryo survival rate was not significantly affected (32% versus 18%). Fifth experiment: vitrification with sucrose supplementation was compared to slow freezing. No significant difference was observed after direct transfer on kidding rate (52% versus 31%, respectively), but embryo survival rate tended to be higher after vitrification (34% versus 2 1 %). In conclusion, our results indicate that addition of 0.4 M sucrose in association with direct transfer improves significantly the viability of goat vitrified embryos. [less ▲]

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