References of "2006"
     in
Bookmark and Share    
Full Text
See detailCoupled modelling of an excavation in a brittle formation
Collin, Frédéric ULg; Li, Xian Ling; Chambon, René et al

Conference (2006)

This paper is concerned with the coupling effects existing between the mechanical problem and the water diffusion process during an excavation, in relation with the nuclear waste disposal concepts. The ... [more ▼]

This paper is concerned with the coupling effects existing between the mechanical problem and the water diffusion process during an excavation, in relation with the nuclear waste disposal concepts. The hydromechanical coupling effects are first evidenced. Then, the permeability variation with damage is studied. Finally, different kind of flow boundary condition are considered. Their influence on the cavity convergence is highlighted and their effect on strain localisation process as well. [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
See detailFeasability of forest conversion: ecological, social and economic aspects (FEFOCON)
Verheyen, Kris; Lust, Noel; Carnol, Monique ULg et al

Report (2006)

Detailed reference viewed: 13 (1 ULg)
Full Text
See detailEffets symptomatiques de la glucosamine dans l’arthrose
Reginster, Jean-Yves ULg; Bruyère, Olivier ULg

in Pharma-Sphère (2006), 110

Detailed reference viewed: 19 (10 ULg)
Full Text
Peer Reviewed
See detailGeorges Didi-Huberman: vers une intentionnalité inversée ?
Hagelstein, Maud ULg

in La part de l'oeil (2006), 21-22

Detailed reference viewed: 56 (0 ULg)
Full Text
Peer Reviewed
See detailAnalytical validation of potentiometric method for cetirizinium ion
Rachidi, Mohamed ULg; Digua, K.; Hubert, Philippe ULg et al

in Analytical Letters (2006), 39(8), 1699-1708

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required ... [more ▼]

Accuracy and reliability of the analytical results are crucial for ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, analytical validation is required. In this matter, many official documents describing the criteria of validation are available. However, these concern mainly chromatography analysis and bio-analytical methods of pharmaceutical products, but they do not propose any experimental protocol for direct potentiometric methods using ion-selective electrodes applied in pharmaceutical analysis. In this work, we are proposing a validation strategy based on the normative and regulatory guidelines applied to a potentiometric method with a polymeric membrane selective to cetirizine dihydrochloride. The statistical analysis obtained from raw data is described for all steps of this protocol. Also this validated method was successfully applied to the determination of cetirizine in pharmaceutical preparations using direct potentiometry with a mean relative standard deviation of 0.57% and a mean recovery of 99.63%. [less ▲]

Detailed reference viewed: 220 (5 ULg)
Full Text
See detailPensions with heterogenous individuals and endogenous fertility
Cremer, Helmuth; Gahvari, Firouz; Pestieau, Pierre ULg

in Journal of Population Economics (2006), (21), 961-981

This paper studies the design of pension schemes in a society where fertility is endogenous and parents differ in their ability to raise children. In a world with perfect information, a pay-as-you-go ... [more ▼]

This paper studies the design of pension schemes in a society where fertility is endogenous and parents differ in their ability to raise children. In a world with perfect information, a pay-as-you-go social security system is characterized by equal pensions for all but different contributions which may or may not increase with the number of children. Additionally, fertility must be subsidized at the margin to correct for the externality that accompanies fertility. In a world of asymmetric information, incentiverelated distortions supplement the Pigouvian subsidy. These may either require an additional subsidy or an offsetting tax on fertility depending on whether the redistribution is towards people with more or less children. In the former case, pensions are decreasing in the number of children; in the latter case, they are increasing. [less ▲]

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailRecombinant human erythropoietin therapy after allogeneic hematopoietic cell transplantation with a nonmyeloablative conditioning regimen: low donor chimerism predicts for poor response.
Vanstraelen, Gaëtan; Baron, Frédéric ULg; Willems, Evelyne ULg et al

in Experimental hematology (2006), 34(7), 841-50

PURPOSE: After allogeneic hematopoietic stem cell transplantation with nonmyeloablative conditioning (NMHCT), many patients experience prolonged anemia and require red blood cell (RBC) transfusions. We ... [more ▼]

PURPOSE: After allogeneic hematopoietic stem cell transplantation with nonmyeloablative conditioning (NMHCT), many patients experience prolonged anemia and require red blood cell (RBC) transfusions. We enrolled 60 consecutive patients undergoing NMHCT in a phase II trial to determine the optimal utilization of recombinant human erythropoietin (rHuEPO) therapy in this setting. PATIENTS AND METHODS: The first 14 NMHCT recipients did not receive rHuEPO (control group). Nineteen patients were scheduled to start rHuEPO on day 0 (EPO group 2) and 27 patients on day 28 after the transplant (EPO group 1). RHuEPO was administered subcutaneously once weekly at a dose of 500 U/kg/wk with the aim of achieving hemoglobin (Hb) levels of 13 g/dL. The 3 groups were well balanced for major characteristics. RESULTS: During the first month (p < 0.0001) as well as days 30 to 100 (p < 0.0001) and days 100 to 180 (p < 0.0001), Hb values were higher in patients receiving rHuEPO compared to those not receiving it. However, transfusion requirements were significantly decreased only in the first month in EPO group 2 (p = 0.0169). T-cell chimerism above 60% on day 42 was the best predictor of Hb response (p < 0.0001) or Hb correction (p = 0.0217), but myeloid chimerism above 90% also predicted for Hb response (p = 0.0069). Hb response was also decreased in patients receiving CD8-depleted grafts and increased in the few patients not receiving TBI, but only in univariate analysis. CONCLUSIONS: Anemia after NMHCT is sensitive to rHuEPO therapy, but less so than after conventional allogeneic HCT. RHuEPO decreases transfusion requirements only in the first 30 days posttransplant. T-cell chimerism below 60% on day 42 impaired Hb response, suggesting possible inhibition of donor erythropoiesis by residual recipient lymphocytes. A prospective randomized trial should be performed with rHuEPO starting on the day of transplantation to assess its clinical benefit in terms of transfusion requirements and quality of life. [less ▲]

Detailed reference viewed: 58 (4 ULg)
Full Text
See detailLangues et immigration dans l’enseignement en Communauté française de Belgique
Lucchini, Silvia ULg

in Conseil supérieur de la langue française et Service de la langue française de la Communauté française de Belgique (Ed.) Langue française et diversité linguistique (2006)

Detailed reference viewed: 51 (4 ULg)
Full Text
Peer Reviewed
See detailVertebrate origins: does the tunic make the man?
Delsuc, Frédéric; Baurain, Denis ULg; Philippe, Hervé

in Medecine Sciences : M/S (2006), 22(8-9, AUG-SEP), 688-690

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailInvasion intracellulaire des cellules non-phagocytaires par Staphylococcus aureus
Boulanger, Delphine; Bureau, Fabrice ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (2006), 150(1), 27-42

Intracellular invasion of Staphyloccocus aureus in nonphagocytic cells Staphylococcus aureus often causes chronic diseases. It is now believed that recurrence of these infections could be related to the ... [more ▼]

Intracellular invasion of Staphyloccocus aureus in nonphagocytic cells Staphylococcus aureus often causes chronic diseases. It is now believed that recurrence of these infections could be related to the ability of S. aureus to invade and persist within nonphagocytic cells. Adherence to eucaryotic cells is crucial for S. aureus to invade and persist within invasion and depends on interactions between bacterial fibronectin-binding proteins, fibronectin and the host cell fibronectin receptor, integrin alpha(5)beta(1). It is currently established that fibronectin acts as a bridging molecule. Penetration of S. aureus in host cells requires also activation of protein tyrosine kinases that mediate signal transduction and actin polymerization leading to cytoskeletal rearrangements. After internalization, S. aureus either remains in membrane-bound vacuoles or appears free in the cytoplasm. After bacterial proliferation, S. aureus induces host cell apoptosis or persist inside cells as small colony variants, which represent a less virulent subpopulation of S. aureus that grows slower. Although numerous in vitro and in vivo studies have demonstrated the ability of S. aureus to invade nonphagocytic cells, additional experiments have to be realized to understand the relevance of intracellular localization in vivo. [less ▲]

Detailed reference viewed: 259 (18 ULg)
Full Text
Peer Reviewed
See detailInclusion of a stress-dependent Preisach model in 2D FE calculations
Benabou, A.; Vandenbossche, L.; Gyselinck, Johan et al

in Compel-the International Journal for Computation and Mathematics in Electrical and Electronic Engineering (2006), 25(1), 81-90

Purpose - Mechanical stress can heavily affect the magnetic behaviour law in ferromagnetic materials. This paper, aims to take into account the effect of mechanical stress into a hystreresis model. This ... [more ▼]

Purpose - Mechanical stress can heavily affect the magnetic behaviour law in ferromagnetic materials. This paper, aims to take into account the effect of mechanical stress into a hystreresis model. This model is implemented in a finite element analysis code and tested in the case of a simple system. Design/methodology/approach - A simple extension of the classical Preisach model is proposed, in which a function linked to the Preisach density is parameterized using the mechanical stress as a supplementary parameter. The methodology is based on experimental measurements for identifying the required function. As a first approach, a linear interpolation is used between the measurements in order to have a continuous evolution of the magneto-mechanical behaviour. This model has been tested in the case of a steel sheet in which width is not constant in order to obtain a non-uniform distribution of stress and magnetic flux density. Findings - The model can predict the magneto-mechanical behaviour with a good accuracy in the case of tensile stress. Implementation of the model in finite element analysis has shown that the model can predict the behaviour of steel sheet subject to a non-uniform stress distribution. Originality/value - This paper shows that a classical hysteresis model can be extended to take into account the magneto-mechanical behaviour. This is useful for the design of electrical machines which are subject to non-negligible mechanical stress. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
See detailSome theoritical and numerical features of strain gradient media regarded as micromorphic media
Caillerie, Denis; Chambon, René; Collin, Frédéric ULg

Conference (2006)

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailA Principal-Agent Theory Approach to Public Expenditure Management Systems in Developing Countries
Leruth, Luc ULg; Paul, Elisabeth ULg

in IMF Working Paper (2006), 06/204

A well-functioning public expenditure management (PEM) system is considered a critical pillar of government efficiency, on par with a low-distortion tax system and efficient tax administration. The paper ... [more ▼]

A well-functioning public expenditure management (PEM) system is considered a critical pillar of government efficiency, on par with a low-distortion tax system and efficient tax administration. The paper discusses PEM systems in developing countries using an analytical framework based on principal-agent theory. This simple model can be applied to various PEM systems, and allows for comparisons between institutional settings. To illustrate this, we analyze the benefits derived from the use by the Ministry of Finance (MoF) of two control instruments; ex post audits and ex ante controls, and assess their value in terms of their ability to deter cheating. We derive a set of possible “control regimes” which can be used by the MoF. Although we illustrate the use of the model using developing countries, it is also relevant to developed economies. [less ▲]

Detailed reference viewed: 64 (4 ULg)
Full Text
Peer Reviewed
See detailMicrobial ecology of the closed artificial ecosystem MELiSSA (Micro-Ecological Life Support System Alternative): Reinventing and compartmentalizing the Earth's food and oxygen regeneration system for long-haul space exploration missions
Hendrickx, Larissa; De Wever, Heleen; Hermans, Veronik et al

in Research in Microbiology (2006), 157

MELiSSA is a bioregenerative life support system designed by the European Space Agency (ESA) for the complete recycling of gas, liquid and solid wastes during long distance space exploration. The system ... [more ▼]

MELiSSA is a bioregenerative life support system designed by the European Space Agency (ESA) for the complete recycling of gas, liquid and solid wastes during long distance space exploration. The system uses the combined activity of different living organisms: microbial cultures in bioreactors, a plant compartment and a human crew. In this minireview, the development of a short-cut ecological system for the biotransformation of organic waste is discussed from a microorganism's perspective. The artificial ecological model—still in full development—that is inspired by Earth's own geomicrobiological ecosystem serves as an ideal study object on microbial ecology and will become an indispensable travel companion in manned space exploration. [less ▲]

Detailed reference viewed: 115 (22 ULg)
See detailSTRATEGY FOR THE QUALITATIVE AND QUANTITATIVE ANALYSIS OF CROP SYRUP CONTAINING ISOMALTOOLIGOSACCHARIDES KNOWN AS EMERGING PREBIOTICS
Goffin, Dorothée ULg

Conference (2006)

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. Recent data obtained in human ... [more ▼]

Isomaltooligosaccharides (IMOs) are non-digestible oligosaccharides, considered as prebiotics and therefore aim to selectively feed probiotics indigenous to the human colon. Recent data obtained in human subjects, support the involvement of dietary oligosaccharides in physiological processes in the different intestinal cell type and also outside the gastrointestinal tract (e.g. hormone production, lipid and carbohydrate metabolism). IMOs consists of glucose monomers linked by at least one α-1-6, or in a lower proportion α -1-3 (nigerose family) or α -1-2 (kojibiose family) glucosidic linkages. In our case they are produced enzymatically from corn starch. It results in a very complex mixture with molecules characterized at the same time by their DP value (from 2 to ~20), linkages types (α-1-2, 3 or 6) and the proportion and position of each type of linkage (only α -1-6 or combined types). The challenge of this study was to find a qualitative and quantitative method to characterize the syrups. In a subsequent study, every unidentified peak could be determined by NMR or Mass spectrometry. Three different chromatographic methods have been tested and compared over their selectivity, sensibility, robustness, applicability and their quantitative power. The HPLC-RID (Refractive Index Detector) used with a Prevail Carbohydrate column (Alltech), adapted for carbohydrates with a certain value of DP, appear to be poorly selective due to the obligation of working in isocratic conditions. The HPLC-ELSD (Evaporating Light Scattering Detector) used with the same column gave a very good separation upon the DP as the Prevail accepts a wide range of solvant changing and even a separation of the different DP 2 molecules. The sensibility was also improved due to the stability of the baseline. The quantitative analysis is a bit more awkward due to the relatively limited linear portion of the calibration curve. High-performance Anion Exchange Chromatography coupled with Pulsed Amperometric Detection (HPAEC-PAD) appeared to deserve a special mention, since it provides selective separation and sensitive detection. In fact, this technique is the only chromatographic one to separate with effectiveness homologue molecules having a difference only in their DP (up to high DPs) or linkage types. This is due to the separation mode based on the difference in ionic force of the sugars in alkaline conditions (mainly due to the DP and the structure of the molecule). However, during the detection, the electrochemical behavior of carbohydrates can be affected by molecular weight as well as by structural differences giving rise to different response factors; as a consequence, HPAEC-PAD is not generally considered as suitable for quantitative studies of complex mixtures of oligosaccharides. In this work a methodological approach is presented in order to get a quantitative response through a rigorous methodology for our IMOs. It also opens the way to the theoretical determination of the response factor for the homologue molecules in relation with their structure and DP. [less ▲]

Detailed reference viewed: 23 (0 ULg)