References of "2006"
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See detailSpotlight on nail histomycology.
Pierard, Gérald ULg; Quatresooz, Pascale ULg; Arrese Estrada, Jorge ULg

in Dermatologic Clinics (2006), 24(3), 371-4

The misdiagnosis of onychomycosis delays the proper treatment of the nail condition. Nail histomycology refers to the microscopic examination of histologic sections prepared from nail clippings for the ... [more ▼]

The misdiagnosis of onychomycosis delays the proper treatment of the nail condition. Nail histomycology refers to the microscopic examination of histologic sections prepared from nail clippings for the purpose of detecting the presence of fungi. This laboratory method is the most sensitive procedure for the diagnosis of onychomycosis. It allows for the visualization of the precise location of the invasive fungus inside the nail apparatus. The method also distinguishes various shapes of the fungal cells, in particular filamentous fungi, yeasts, conidia, and sporodochia. The correct diagnosis provided by histomycology combined with culture not only allows for more efficient expenditure of funds and services but also is important for the timely alleviation of the disorder. [less ▲]

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See detailThe Treatment of Severe Postmenopausal Osteoporosis : A Review of Current and Emerging Therapeutic Options
Reginster, Jean-Yves ULg; Sarlet, Nathalie ULg

in Treatments in Endocrinology (2006), 5(1), 15-23

Several chemical entities have shown their ability to reduce axial and/or appendicular fractures in patients with osteoporosis. Since patients who have experienced a previous fracture are at high risk for ... [more ▼]

Several chemical entities have shown their ability to reduce axial and/or appendicular fractures in patients with osteoporosis. Since patients who have experienced a previous fracture are at high risk for subsequent vertebral or hip fracture, it is of prime importance to treat such patients with medications that have unequivocally demonstrated their ability to reduce fracture rates in patients with prevalent fractures. Results obtained with calcium and vitamin D, in this particular population, are not fully satisfactory and these medications are probably better used in conjunction with other therapeutic regimens. Bisphosphonates have shown their ability to reduce vertebral (alendronate, risedronate, ibandronate) and non-vertebral (alendronate, risedronate) fractures in patients with established osteoporosis. Raloxifene has also shown similar properties, notwithstanding its effect on non-vertebral fractures, which has only been derived from a post hoc analysis limited to patients with prevalent severe vertebral fractures at baseline. This compound also has interesting non-skeletal benefits, including effects on the breast and heart. Teriparatide, a bone-forming agent, promptly reduces the rate of vertebral and all non-vertebral fractures, without significant adverse effects. Strontium ranelate, the first agent shown to concomitantly decrease bone resorption and stimulate bone formation, has also shown its ability to reduce rates of vertebral and non-vertebral fractures in patients with established osteoporosis. It significantly reduces hip fractures in elderly individuals at high risk for such events. Its safety profile is also excellent. [less ▲]

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See detailTargeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions
Bearzatto, Bertrand; Servais, Laurent; Roussel, Céline et al

in FASEB Journal (2006), 20

SPECIFIC AIMS Inactivation of gene coding for calretinin, a calcium binding protein acting as a fast calcium buffer, deeply altered the cerebellar physiology leading to motor discoordination. Although ... [more ▼]

SPECIFIC AIMS Inactivation of gene coding for calretinin, a calcium binding protein acting as a fast calcium buffer, deeply altered the cerebellar physiology leading to motor discoordination. Although mechanistic hypotheses have been proposed to explain these alterations, the widespread expression of calretinin in the whole central nervous system and its expression in several neuronal types in the cerebellar circuitry preclude a precise mechanistic demonstration. The aim of this study was to determine to what extent the expression of calretinin in a specific neuronal cell type, the cerebellar granule cells, contributes to the phenotype detected in calretinin knockout (Cr–/–) mice. To achieve this objective, we constructed transgenic Cr–/– mice exhibiting a selective re-expression of Cr in granule cells (hereafter referred to as Cr-rescue) through the promoter function of the GABAA receptor {alpha}6 subunit gene. [less ▲]

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See detailStress echocardiography – a review
Sandersen, Charlotte ULg; Amory, Hélène ULg

in Proceedings of the Progress in Equine Sports Medicine (ESPOM) (2006)

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See detailPerformances thermiques initiales de produits minces réfléchissants
Flamant, Gilles; Wouters, Peter; L'Heureux, Didier et al

Report (2006)

La méthodologie retenue consistait à déterminer les performances thermiques des PMR, d’une part, sur la base de mesures en laboratoire (dans des conditions aux limites stationnaires) et, d’autre part, sur ... [more ▼]

La méthodologie retenue consistait à déterminer les performances thermiques des PMR, d’une part, sur la base de mesures en laboratoire (dans des conditions aux limites stationnaires) et, d’autre part, sur la base de mesures réalisées dans des cellules d’essai soumises à des conditions extérieures réelles (régime par essence non stationnaire). Les résultats de ces deux types de mesures ont été comparés entre eux ainsi qu’à des résultats de calculs réalisés onformément aux normes en vigueur. [less ▲]

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See detailBiodegradable microparticles loaded with thrombin receptor agonist peptide for gastric ulcer treatment in rats
Markvicheva, E.; Stashevskaya, K.; Strukova, S. et al

in Journal of Drug Delivery Science and Technology (2006), 16(4, JUL-AUG), 321-325

The aim of the current paper was to elaborate an immobilization method of thrombin receptor agonist peptide (TRAP-6) in biodegradable biocompatible poly(d,l)-lactide-co-glycolide (PLGA) inicroparticles ... [more ▼]

The aim of the current paper was to elaborate an immobilization method of thrombin receptor agonist peptide (TRAP-6) in biodegradable biocompatible poly(d,l)-lactide-co-glycolide (PLGA) inicroparticles and to demonstrate the effect of the entrapped peptide for tissue repair, namely,for a gastric ulcer treatment in rats. TRAP-6 was entrapped in polymer using w/o/w double emulsion-evaporation technique. The morphology of empty and TRAP-6 loaded microparticles was evaluated by light and scanning electron microscopy (SEM). In vitro release kinetics profile of TRAP-6 from microparticles was studied by HPLC. To investigate gastric mucosal protection effect in vivo, TRAP-6-loaded microparticles were administered in a rat stomach after a previous mucosal injury (a gastric ulcer). Microparticles with entrapped TRAP-6 were found to reduce both an inflammation and proliferation phases of wound healing, and thus accelerated tissue repair in rats. [less ▲]

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See detailHenri Foucault. Arts de la lumière: le corps diaphane dans la photographie sculptée
Dondero, Maria Giulia ULg

in Nouveaux Actes Sémiotiques (2006), 104-106

Cet article analyse l’exposition de l’artiste Henri Foucault au Palazzo Fortuny lors de la Biennale de Venise en 2005, et notamment deux œuvres très originales qui problématisent le rapport entre ... [more ▼]

Cet article analyse l’exposition de l’artiste Henri Foucault au Palazzo Fortuny lors de la Biennale de Venise en 2005, et notamment deux œuvres très originales qui problématisent le rapport entre photographie et sculpture. Ces objets (à échelle naturelle) mettent le corps féminin au centre de la représentation : il s’agit d’un corps en extase (individuel) et d’un corps sacrificiel (collectif). J’ai analysé à cette occasion les relations entre support (formel et matériel) de la photographie et apport du geste sculptural. [less ▲]

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See detailUse of Posidonia oceanica sheaths as a biomonitor of metal pollution.
Gosselin, Marc; Bouquegneau, Jean-Marie ULg; Pergent, Gérard et al

in Biologia Marina Mediterranea (2006), 13

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See detailFunctional morphology of Tethya species (Porifera): 2. Three-dimensional morphometrics on spicules and skeleton superstructures of T-minuta
Nickel, M.; Bullinger, Eric ULg; Beckmann, F.

in Zoomorphology (2006), 125(4), 225-239

The biomechanics of body contraction in Porifera is almost unknown, although sponge contraction has been observed already in ancient times. Some members of the genus Tethya represent the most contractile ... [more ▼]

The biomechanics of body contraction in Porifera is almost unknown, although sponge contraction has been observed already in ancient times. Some members of the genus Tethya represent the most contractile poriferan species. All of them show a highly ordered skeleton layout. Based on three main spicule types, functional units are assembled, termed skeleton superstructures here. Using synchrotron radiation based x-ray microtomography and quantitative image analysis with specially developed particle and structure recognition algorithms allowed us to perform spatial allocation and 3D-morphometric characterizations of single spicules and skeleton superstructures in T. minuta. We found and analyzed three skeleton superstructures in the investigated specimen: (1) 85 megasclere bundles, (2) a megaster sphere, composed by 16,646 oxyasters and (3) a pinacoderm-tylaster layer composed by micrasters. All three skeleton superstructures represent composite materials of siliceous spicules and extracellular matrix. From structure recognition we developed an abstracted mathematical model of the bundles and the sphere. In addition, we analyzed the megaster network interrelation topology and found a baso-apical linear symmetry axis for the megaster density inside the sphere. Based on our results, we propose a hypothetical biomechanical contraction model for T. minuta and T. wilhelma, in which the skeleton superstructures restrain physical stress generated by contraction in the tissue. While skeletal structures within the genus Tethya have been explained using R. Buckminster Fullers principle of tensegrity by other authors, we prefer material science based biomechanical approaches, to understand skeletal superstructures by referring to their composite material properties. [less ▲]

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See detailEcrire et dessiner en éveil scientifique: Un reflet des apprentissages et des potentialités des élèves
Giot, Bernadette ULg; Quittre, Valérie ULg

in Actes du 4e Congrès des chercheurs en Education, Namur, 21 et 22 mars 2006. (2006)

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See detailL’effet de l’atmosphère terrestre sur les GNSS : une perturbation ou un signal géophysique ?
Warnant, René ULg

in Bulletin de la Société Géographique de Liège (2006), 47

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See detailQuasi steady-state simulation diagnosis using Newton method with optimal multiplier
Rousseaux, Patricia ULg; Van Cutsem, Thierry ULg

in IEEE PES General Meeting (Montreal) (2006)

This paper deals with the quasi steady-state approximation of the long-term dynamics. This fast time simulation method assumes that the short-term dynamics are stable and can be replaced by their ... [more ▼]

This paper deals with the quasi steady-state approximation of the long-term dynamics. This fast time simulation method assumes that the short-term dynamics are stable and can be replaced by their equilibrium equations. When the latter stop having a solution, the simulation undergoes a singularity. This paper proposes a method to identify which component(s) are responsible for the loss of equilibrium. The corresponding equations are identified using the Newton method with optimal multiplier. The method has been validated with respect to full time simulation. Very good results are shown on the Nordic-32 system, in cases where long-term voltage instability triggers loss of synchronism. The proposed method enhances time simulation at very low computational cost and can also help correcting model and/or operating point errors. [less ▲]

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See detailThe roles of complexing agents in the sulfidisation and xanthate flotation of cobalt oxy hydroxides of copper-cobalt oxides ores from the Congolese Copperbelt
Bastin, David ULg; Frenay, Jean ULg; Vermaut, Norbert

Conference (2006)

Complex mineralogy combined with a variable chemistry lead to various flotation responses of cobalt oxy-hydroxides present in oxidised and mixed copper-cobalt stratiform deposits of the Central African ... [more ▼]

Complex mineralogy combined with a variable chemistry lead to various flotation responses of cobalt oxy-hydroxides present in oxidised and mixed copper-cobalt stratiform deposits of the Central African Copperbelt. Optimum metallurgical results require very high dosages of reagents and the management of such high chemicals concentrations in the pulp at the plant scale is delicate. The transition period between high reducing conditions during the sulfidisation step and a more oxidising environment prevailing during collector adsorption is particularly critical. This paper demonstrates how the use of copper and cobalt complexing agents can significantly improve the process control and metallurgical performance. The different modes of action of these reagents are presented and mechanisms for the various reactions proposed. Plant results following the introduction of ammonium sulfate at the New Concentrator of Kipushi are discussed. [less ▲]

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See detailEvaluation des troubles fonctionnels du système respiratoire du cheval
Salinas, E.; Van Erck, Emmanuelle ULg; Lekeux, Pierre ULg et al

in Pratique Vétérinaire Equine (2006), 38(150), 29-39

Les troubles respiratoires sont fréquents chez le cheval. Il existe des tests fonctionnels complémentaires, réalisables soit sur le terrain soit en centres spécialisés.

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See detailThe immune system as a foundation for immunologic therapy and hematologic malignancies: a historical perspective.
Baron, Frédéric ULg; Storb, Rainer

in Bailliere's Best Practice & Research. Clinical Haematology = Best Practice & Research. Clinical Haematology (2006), 19(4), 637-53

In this review we aim to provide a historical overview of the immunotherapeutic approaches which have been developed for the treatment of hematological malignancies. After briefly summarizing the ... [more ▼]

In this review we aim to provide a historical overview of the immunotherapeutic approaches which have been developed for the treatment of hematological malignancies. After briefly summarizing the development of the theory of cancer immune surveillance, we describe how initial studies discovering the efficacy of the immune-mediated graft-versus-tumor effects after allogeneic hematopoietic cell transplantation led to new transplantation approaches (termed non-myeloablative transplantation) relying almost exclusively on graft-versus-tumor effects for tumor eradication. We then summarize important steps in the development of tumor vaccines and autologous adoptive immunotherapy in patients with hematological malignancies. Finally, we describe historical discoveries leading to the recent success with monoclonal antibodies as treatment for lymphomas, chronic lymphocytic leukemia, and acute myeloid leukemia. [less ▲]

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See detailObservations
Lecocq, Pascale ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2006), (mars-avril),

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See detailLa participation piège à ....
Jacquemain, Marc ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2006)

The participation of stakeholders has commonly become a criterion for the assessment of public policies. In the field of integration of unskilled workers, who are more and more integrated to compulsory ... [more ▼]

The participation of stakeholders has commonly become a criterion for the assessment of public policies. In the field of integration of unskilled workers, who are more and more integrated to compulsory "reskilling" devices, is participation a benefit or a way to produce consent ? At the light of the work of Tyler and McGraw, this paper examines data that were collected in a process of sociological intervention among those unskilled worker in different regions of Wallonia [less ▲]

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