References of "2006"
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See detailEffets potentiels du stress sur les performances de reproduction en élevage bovin
Hanzen, Christian ULg

in Annales de la Faculté de Médecine Vétérinaire de l'UNILU (2006), XVII(1), 26-31

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See detailEfficacy of ceftiofur and flunixin in the early treatment of bronchopneumonia in weaners
Halloy, D. J.; Cambier, Carole ULg; Gustin, Pascal ULg

in Veterinary Record : Journal of the British Veterinary Association (2006), 158(9), 291-296

Three groups of five pigs were inoculated intratracheally with Escherichia coli lipopolysaccharides, and 24 hours later with 10 x 10(9) colony-forming units of a non-toxigenic strain of Pasteurella ... [more ▼]

Three groups of five pigs were inoculated intratracheally with Escherichia coli lipopolysaccharides, and 24 hours later with 10 x 10(9) colony-forming units of a non-toxigenic strain of Pasteurella multocida type A; a fourth group was left uninoculated as controls. The three inoculated groups received either no treatment (positive controls), or were treated with 3 mg/kg ceftiofur intramuscularly once a day for five consecutive days, either alone or combined with 2 mg/kg flunixin intramuscularly once a day for three consecutive days. The sustained coughing and hyperthermia recorded in the positive controls disappeared after two days and three days of treatments, respectively, in the treated animals, and the reductions in daily weight gain and changes in breathing pattern observed in the controls were not observed in the treated animals. There were no significant differences between the pigs treated with ceftiofur alone or ceftiofur combined with flunixin. In the positive controls, the number of inflammatory cells in samples of bronchoalveolar lavage fluid continued to increase up to 15 days after inoculation, whereas in the treated animals there were similar increases at six days but the numbers had decreased to baseline levels after 15 days. Similarly, in the treated animals the volume of the lung lesions was significantly less than in the control animals, but the inclusion of flunixin in the treatment regimen had no significant additional effect [less ▲]

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See detailPositive and negative ion mode ESI-MS and MS/MS for studying drug-DNA complexes
Rosu, Frédéric ULg; Pirotte, Sophie ULg; De Pauw, Edwin ULg et al

in International Journal of Mass Spectrometry (2006), 253(3), 156-171

We report systematic investigation of duplex DNA complexes with minor groove binders (Hoechsts 33258 and 33342, netropsin and DAPI) and intercalators (daunomycin, doxorubicin, actinomycin D, ethidium ... [more ▼]

We report systematic investigation of duplex DNA complexes with minor groove binders (Hoechsts 33258 and 33342, netropsin and DAPI) and intercalators (daunomycin, doxorubicin, actinomycin D, ethidium, cryptolepine, neocryptolepine, m-Amsacrine, proflavine, ellipticine and mitoxantrone) by ESI-MS and ESI-MS/MS in the negative ion mode and in the positive ion mode. The apparent solution phase equilibrium binding constants can be determined by measuring relative intensities in the ESI-MS spectrum. While negative ion mode gives reliable results, positive ion mode gives a systematic underestimation of the binding constants and even a complete suppression of the complexes for intercalators lacking functional groups capable of interacting in the grooves. In the second part of the paper we systematically compare MS/MS fragmentation channels and breakdown curves in the positive and the negative modes, and discuss the possible uses and caveats of MS/MS in drug-DNA complexes. In the negative mode, the drugs can be separated in three groups: (1) those that leave the complex with no net charge; (2) those that leave the complex with a negative charge; and (3) those that remain attached on the strands upon dissociation of the duplex due to their positive charge. In the positive ion mode, all complexes fragment via the loss of protonated drug. Information on the stabilization of the complex by drug-DNA noncovalent interactions can be obtained straightforwardly only in the case of neutral drug loss. In all other cases, proton affinity (in the positive ion mode), gas-phase basicity (in the negative ion mode) and coulombic repulsion are the major factors influencing the fragmentation channel and the dissociation kinetics. [less ▲]

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See detailG-quadruplexes in telomeric repeats are conserved in a solvent-free environment
Baker, Erin Shammel; Bernstein, Summer L; Gabelica, Valérie ULg et al

in International Journal of Mass Spectrometry (2006), 253(3), 225-237

The structural properties of G-quadruplex forming sequences. such as the human telomeric repeat d(T(2)AG(3))(n), are of great interest due to their role in cancer and cellular aging. To determine if G ... [more ▼]

The structural properties of G-quadruplex forming sequences. such as the human telomeric repeat d(T(2)AG(3))(n), are of great interest due to their role in cancer and cellular aging. To determine if G-quadruplexes are present in a solvent-free environment. different lengths of the telomeric repeat d(T(2)AG(3))(n) (where n = 1, 2, 4 and 6) and dTG(4)T were investigated with mass specteometry, ion mobility and molecular dynamics calculations. Nano-ESI-MS illustrated quadruples stoichiometries compatible with G-quadruplex Structure.; for each sequence, with dT(2)AG(3) and dTG(4)T forming 4-strand complexes with two and three NH4+ adducts. d(T(2)AG(3))(2) a 2-strand complex. and d(T(2)AG(3))(4) and d(T(2)AG(3))(6) remaining single-stranded. Experimental cross sections were obtained for all species using ion mobility method.,. In all case.,. these could be quantitatively matched to model cross sections with specific strand orientations (parallel/antiparallel) and structures. For each species, the solvent-free structures agreed with the solution CD measurements, but the ion mobility/modeling procedure often gave Much more detailed structural information. (C) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailPartenariat F.N.P.S.M.S. - ULg / Rapport d'activité ULg 2005
Périlleux, Claire ULg; Van Kerkhoven, Fabrizio; Jennès, Nicolas

Report (2006)

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See detailLa participation piège à ....
Jacquemain, Marc ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2006)

The participation of stakeholders has commonly become a criterion for the assessment of public policies. In the field of integration of unskilled workers, who are more and more integrated to compulsory ... [more ▼]

The participation of stakeholders has commonly become a criterion for the assessment of public policies. In the field of integration of unskilled workers, who are more and more integrated to compulsory "reskilling" devices, is participation a benefit or a way to produce consent ? At the light of the work of Tyler and McGraw, this paper examines data that were collected in a process of sociological intervention among those unskilled worker in different regions of Wallonia [less ▲]

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See detailSound production mechanism in Amphiprion clarkii (Teleostei: Pomacentridae)
Colleye, Orphal ULg; Herrel, Anthony; Vandewalle, Pierre ULg et al

Poster (2006)

In the family Pomacentridae, six genera were reported as sound producers: Amphiprion, Dascyllus, Stegastes, Chromis, Abudefduf and Plectroglyphidodon. The anemonefishes (Amphiprioninae) live in social ... [more ▼]

In the family Pomacentridae, six genera were reported as sound producers: Amphiprion, Dascyllus, Stegastes, Chromis, Abudefduf and Plectroglyphidodon. The anemonefishes (Amphiprioninae) live in social group in association with sea anemones, which protect them from predators. Their sound emissions seem involved in courtship and territorial defense, contributing to both survival and reproductive success. However, the mechanism of sound production is unresolved. It has been hypothesized that it involves swimbladder or the action of the pharyngeal jaws amplified by swimbladder. The aim of this study was to understand the sonic mechanism involved in the agonistic sounds in Amphiprion clarkii. The approach consists in high-speed cineradiography and functional morphology. During agonistic sounds (pops), fishes perform different movements such as skull elevation, pectoral girdle retraction, hyoid lowering and mouth closing. Pops are produced when the hyoid is completely lowered and the mouth closed. The simultaneous realization of these movements was never observed in teleost. In Amphiprion sp., it is possible due to an additional ligament inserted on the hyoid bar and on the inner lower jaw. The hyoid lowering combined to the closing (and thus the elevation) of the mandible could generate a tension of the ligament, provoking its vibration [less ▲]

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See detailReconstruction of glottic defects after endoscopic cordectomy: voice outcome.
Remacle, Marc; Lawson, Georges; Morsomme, Dominique ULg et al

in Otolaryngologic Clinics of North America (2006), 39(1), 191-204

Medialization thyroplasty for correction of glottic gap, keel placement after laser-assisted section, and topical application of mitomycin-C for anterior glottic synechiae are effective procedures for ... [more ▼]

Medialization thyroplasty for correction of glottic gap, keel placement after laser-assisted section, and topical application of mitomycin-C for anterior glottic synechiae are effective procedures for voice restoration after endoscopic cordectomy. Only a minority of patients (16.4% of the authors’ patients after total or extended cordectomies) request this voice restoration. In this regard, self-evaluation questionnaires (eg, VHI) probably are the most useful tools, along with stroboscopy, for voice assessment. Careful elevation of the fibrous tissue from the inner surface of the thyroid cartilage is a tedious and lengthy step, but is critical in successful medialization after cordectomy; therefore, general anesthesia is preferable. Transoral keel placement is still advisable in cases of thick synechiae. The Lichtenberger technique has been a major advancement to the transoral approach, and is the preferred technique of the authors. [less ▲]

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See detailVariation und kontaktinduzierter Wandel im Altschwedischen
Zeevaert, Ludger ULg

Book published by Sonderforschungsbereich Mehrsprachigkeit (2006)

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See detailAntiviral efficacy and resistance in patients on antiretroviral therapy in Kigali, Rwanda: the real-life situation in 2002.
Fischer, A; Karasi, Jean Claude ULg; Kibibi, D et al

in HIV Medicine (2006), 7(1), 64-6

Our study aimed to complete the published data on ARV therapy in Africa by describing the baseline situation in Rwanda before the launch of a large ARV programme (ESTHER). Prescription habits, frequency ... [more ▼]

Our study aimed to complete the published data on ARV therapy in Africa by describing the baseline situation in Rwanda before the launch of a large ARV programme (ESTHER). Prescription habits, frequency and reasons for treatment interruptions but also antiviral efficay, resistance to ARVs and genotypic variability of the viruses present in Rwanda were analysed. Among the 233 patients included in the study, it appeared that a vast majority (91%) were under triple therapy and that half of them had experienced at least one treatment interruption caused mainly by drug shortage or financial difficulties. Among 60 blood samples analysed, 26 were in virological failure with a viral load above 1000 RNA copies/ml and 11 presented major drug resistance mutations. Finally, virological failure could mainly be explained by the high frequency of treatment interruptions but also by the emergence of drug resistance mutations. Consequently the major objective for the ESTHER programme to improve the situation in Rwanda will be to reduce the drug shortage and facilitate the financial accessibility of the treatments. [less ▲]

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See detailDynamics of spontaneous ventricular fibrillation in acutely ischemic pigs
Desaive, Thomas ULg; Janssen, Nathalie ULg; Péters, F. et al

in Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology (2006), 8 (supplement 1)

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See detailEffect of incubation temperature and relative humidity on lesion diameter of Botrytis cinerea Pers. and Penicillium expansum Link. on apple fruits.
Lahlali, R.; Friel, D.; Serrhini, M Najib et al

in Communications in agricultural and applied biological sciences (2006), 71(3 Pt B),

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See detailFunctional morphology of Tethya species (Porifera): 2. Three-dimensional morphometrics on spicules and skeleton superstructures of T-minuta
Nickel, M.; Bullinger, Eric ULg; Beckmann, F.

in Zoomorphology (2006), 125(4), 225-239

The biomechanics of body contraction in Porifera is almost unknown, although sponge contraction has been observed already in ancient times. Some members of the genus Tethya represent the most contractile ... [more ▼]

The biomechanics of body contraction in Porifera is almost unknown, although sponge contraction has been observed already in ancient times. Some members of the genus Tethya represent the most contractile poriferan species. All of them show a highly ordered skeleton layout. Based on three main spicule types, functional units are assembled, termed skeleton superstructures here. Using synchrotron radiation based x-ray microtomography and quantitative image analysis with specially developed particle and structure recognition algorithms allowed us to perform spatial allocation and 3D-morphometric characterizations of single spicules and skeleton superstructures in T. minuta. We found and analyzed three skeleton superstructures in the investigated specimen: (1) 85 megasclere bundles, (2) a megaster sphere, composed by 16,646 oxyasters and (3) a pinacoderm-tylaster layer composed by micrasters. All three skeleton superstructures represent composite materials of siliceous spicules and extracellular matrix. From structure recognition we developed an abstracted mathematical model of the bundles and the sphere. In addition, we analyzed the megaster network interrelation topology and found a baso-apical linear symmetry axis for the megaster density inside the sphere. Based on our results, we propose a hypothetical biomechanical contraction model for T. minuta and T. wilhelma, in which the skeleton superstructures restrain physical stress generated by contraction in the tissue. While skeletal structures within the genus Tethya have been explained using R. Buckminster Fullers principle of tensegrity by other authors, we prefer material science based biomechanical approaches, to understand skeletal superstructures by referring to their composite material properties. [less ▲]

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See detailDegré d'atteinte nerveuse périphérique dans la SLA, la SLP et la maladie de Kennedy
WANG, François-Charles ULg; Le Forestier, Nadine; GERARD, Pascale ULg et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2006)

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See detailExperimental evidences of a structural and dynamical transition in fish school
Becco, Christophe ULg; Vandewalle, Nicolas ULg; Delcourt, Johann ULg et al

in Physica A: Statistical Mechanics and its Applications (2006), 367

We have developed a video tracking system in order to determine all the trajectories of young fish (Oreochromis niloticus L.) within a school. Both individual and collective behaviours have been studied ... [more ▼]

We have developed a video tracking system in order to determine all the trajectories of young fish (Oreochromis niloticus L.) within a school. Both individual and collective behaviours have been studied as a function of the number of fish per unit area. By studying distributions of distances between fish and distributions of relative orientations, structural effects and cooperative motions have been evidenced. Signatures of a phase transition have been found, as predicted by some numerical models. This work opens new perspectives in the study of collective phenomena in biological systems since it is the first time that such measurements are possible. [less ▲]

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