References of "2006"
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See detailLe fonctionnement de la mémoire épisodique dans la maladie d'Alzheimer
Adam, Stéphane ULg

in Belin, Catherine; Ergis, Anne-Marie; Moreau, Olivier (Eds.) Actualités sur les démences: Aspects cliniques et neuropsychologiques (2006)

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See detailFace au chaos des arts numériques
Bawin, Julie ULg

in Flux News (trimestriel d'art contemporain) (2006), (42), 23

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See detailMechanochemistry: targeted delivery of single molecules
Duwez, Anne-Sophie ULg; Cuenot, Stéphane; Jérôme, Christine ULg et al

in Nature Nanotechnology (2006), 1

The use of scanning probe microscopy-based techniques to manipulate single molecules(1) and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological ... [more ▼]

The use of scanning probe microscopy-based techniques to manipulate single molecules(1) and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological challenge(2,3). The ultimate physical limit in the design and fabrication of organic surfaces can be reached using this approach. Here we show that the atomic force microscope (AFM), which has been used extensively to investigate the stretching of individual molecules(4-12), can deliver and immobilize single molecules, one at a time, on a surface. Reactive polymer molecules, attached at one end to an AFM tip, are brought into contact with a modified silicon substrate to which they become linked by a chemical reaction. When the AFM tip is pulled away from the surface, the resulting mechanical force causes the weakest bond - the one between the tip and polymer - to break. This process transfers the polymer molecule to the substrate where it can be modified by further chemical reactions. [less ▲]

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See detailLe rôle pivot des variables latentes pourle raisonnement statistique conditionnel. Exemples d'applications environnementales des processus ponctuels marqués.
Parent, E.; Bernier, J.; Boreux, Jean-Jacques ULg

in Revue de Statistique Appliquée (2006), 54(4), 85-111

En statistique bayésienne, le raisonnement conditionnel probabiliste fonde la solidarité étroite entre modélisation et inférence. Dans le cadre de ce raisonnement, un rôle pivot est joué par les variables ... [more ▼]

En statistique bayésienne, le raisonnement conditionnel probabiliste fonde la solidarité étroite entre modélisation et inférence. Dans le cadre de ce raisonnement, un rôle pivot est joué par les variables latentes. Ce mode de raisonnement peut s’avérer utile aussi en statistique fréquentiste. On présente trois séries hydrométéorologiques décrites par des modèles de processus ponctuels marqués de complexité croissante. Sur ces exemples, on montre comment récolter les fruits de la souplesse de modélisation et des facilités de calcul apportées par les variables latentes. Ces variables améliorent la conceptualisation de variables de structure dans les modèles statistiques et permettent aux calculs d’inférence de bénéficier des algorithmes MCMC en relation avec les techniques «d’augmentation de données». [less ▲]

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See detailImproving control of storage diseases on apple by combining biological and physical postharvest methods
Creemers, P.; Van Laer, S.; Vorstermans, B. et al

Poster (2006)

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See detailPercutaneous coronary intervention for bifurcation disease.A consensus view from the first meeting of the European Bifurcation Club.
Thomas, Martyn; Hildick-Smith, David; Louvard, Yves et al

in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (2006), 2(2), 149-53

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See detailCompte rendu des actes du colloque : Identités franciscaines à l’âge des réformes
Delfosse, Annick ULg

in Moyen Age (Le) (2006), 112(3-4), 692-693

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See detailLe monde souterrain : la genèse des cavernes
Ek, Camille ULg

in Bulletin de la Société Royale des Sciences de Liège (2006), 75

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See detailThe conundrum of the electromagnetic semicircular lipoatrophy
QUATRESOOZ, Pascale ULg; PIERARD, Gérald ULg

in Kosmetische Medizin (2006)

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See detailEffect Of Various Levels Of Imbalance Between Energy And Nitrogen Release In The Rumen On Microbial Protein Synthesis And Nitrogen Metabolism In Growing Double-Muscled Belgian Blue Bulls Fed A Corn Silage-Based Diet
Valkeners, Damien; Thewis, André ULg; Amant, Stéphanie et al

in Journal of Animal Science (2006), 84(4), 877-885

Seven double-muscled Belgian Blue bulls (initial BW: 341 ± 21 kg) with cannulas in the rumen and proximal duodenum were used in an incomplete replicated Latin square. The study examined the effect of ... [more ▼]

Seven double-muscled Belgian Blue bulls (initial BW: 341 ± 21 kg) with cannulas in the rumen and proximal duodenum were used in an incomplete replicated Latin square. The study examined the effect of imbalance between energy and N in the rumen on microbial protein synthesis and N metabolism by giving the same diet according to 3 different feeding patterns. The feed ingredients of the diet were separated into 2 groups supplying the same amount of fermentable OM(FOM) but characterized by different levels of ruminally degradable N (RDN). The first group primarily provided energy for the ruminal microbes (12.5 g of RDN/kg of FOM), whereas the second provided greater N (33.3 g of RDN/kg of FOM). These 2 groups were fed to the bulls in different combinations with the aim of creating 3 levels of imbalance (0, 20, and 40 g/ kg of DM) between energy andN supplies in the rumen. Imbalance was measured by the variation of the degradable protein balance (OEB value in the Dutch system) of the diet between the 2 meals each a day. Diurnal variations in ruminal NH3-N concentrations and plasma urea concentrations were greatly influenced by the feeding patterns of the diet. Introduction of imbalance affected neither microbial N flow at the duodenum (P = 0.97) nor efficiency of growth (P = 0.54). The feeding patterns of the diet had no negative impact on NDF degradation in the rumen (P = 0.33). Nitrogen retention was not affected by imbalance (P = 0.74) and reached 49.7, 52.0, and 51.3 g/d, respectively for 0, 20, and 40 g of OEB/kg of DM imbalance. It seems that introduction of an imbalance between energy and N supplies for the ruminal microbes by altering the feeding pattern of the same diet does not negatively influence the microbial activity in the rumen norNretention of the animal. Nitrogen recycling in the rumen plays a major role in regulating the amount of ruminally available N and allows a continuous synchronization of N and energyyielding substrates for the microorganisms in the rumen. Therefore, imbalance between dietary energy and N created over a 24-h interval was not detrimental to rumen microbial growth for the animal as long as the level of imbalance did not exceed 40 g of OEB/kg of DM. Thus, these feeding patterns of the diet can be used under practical feeding conditions with minimal impact on the performance of ruminant animals for meat production. [less ▲]

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See detailLa mise en état des causes sur la base de l'article 4 du titre préliminaire du Code de procédure pénale
Michiels, Olivier ULg

in Jurisprudence de Liège, Mons et Bruxelles (JLMB) (2006)

L'article est publié sous un jugement pronconé par le tribunal de police de Nivelles. Il donne l'occasion à l'auteur de rappeler, en quelques points, la procédure de la mise en état des intérêts civils ... [more ▼]

L'article est publié sous un jugement pronconé par le tribunal de police de Nivelles. Il donne l'occasion à l'auteur de rappeler, en quelques points, la procédure de la mise en état des intérêts civils telle qu'elle est organisée par le nouvel article 4 du titre préliminaire du code de procédure pénale. [less ▲]

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See detailFour-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
Cruyssen, B. V.; Van Looy, S.; Wyns, B. et al

in Arthritis Research & Therapy (2006), 8(4), 112

Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-alpha agents, few studies have examined the long-term effects. We evaluated 511 patients with ... [more ▼]

Although there is strong evidence supporting the short-term efficacy and safety of anti-tumour necrosis factor-alpha agents, few studies have examined the long-term effects. We evaluated 511 patients with long-standing refractory rheumatoid arthritis treated with intravenous infusions of infliximab 3 mg/kg at weeks 0, 2, 6, and 14 and every 8 weeks thereafter for 4 years. Among the initial 511 patients included in the study, 479 could be evaluated; of these, 295 (61.6%) were still receiving infliximab treatment at year 4 of follow-up. The most common reasons for treatment discontinuation were lack of efficacy (65 patients, 13.6%), safety (81 patients, 16.9%), and elective change (38 patients, 7.9%). Analysis of disease activity scores (DAS28 [ disease activity score based on the 28-joint count]) over time showed that, after the initial rapid improvement during the first 6 to 22 weeks of therapy, a further decrease in disease activity of 0.2 units in the DAS28 score per year was observed. DAS28 scores, measured at week 14 or 22, were found to predict subsequent discontinuation due to lack of efficacy. In conclusion, long-term maintenance therapy with infliximab 3 mg/kg is effective in producing further reductions in disease activity. Disease activity measured by the DAS28 at week 14 or 22 of infliximab therapy was the best predictor of long-term attrition. [less ▲]

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See detailLes angles corniculaires et l'infiniment petit
Bair, Jacques ULg; Henry, Valérie ULg

in Tangente Sup (2006), 31(mai-juin), 4-7

Nous mettons en évidence le fait que des angles entre un demi-cercle et une droite tangente mène au concept d'infiniment petit.

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See detailCoupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis.
Nguyen, Laurent ULg; Besson, Arnaud; Roberts, James M et al

in Cell Cycle (Georgetown, Tex.) (2006), 5(20), 2314-8

The generation of new neurons in the cerebral cortex requires that progenitor cells leave the cell cycle and activate specific programs of differentiation and migration. Genetic studies have identified ... [more ▼]

The generation of new neurons in the cerebral cortex requires that progenitor cells leave the cell cycle and activate specific programs of differentiation and migration. Genetic studies have identified some of the molecules controlling these cellular events, but how the different aspects of neurogenesis are integrated into a coherent developmental program remains unclear. One possible mechanism implicates multifunctional proteins that regulate, both cell cycle exit and cell differentiation.(1) A prime example is the cyclin-dependent kinase inhibitor p27(Kip1), which has recently been shown to function beyond cell cycle regulation and promote both neuronal differentiation and migration of newborn cortical neurons, through distinct and separable mechanisms. p27(Kip1) is therefore part of a machinery that couples the multiple events of neurogenesis in the cerebral cortex. [less ▲]

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See detailProneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.
Castro, Diogo S; Skowronska-Krawczyk, Dorota; Armant, Olivier et al

in Developmental Cell (2006), 11(6), 831-44

Proneural proteins play a central role in vertebrate neurogenesis, but little is known of the genes that they regulate and of the factors that interact with proneural proteins to activate a neurogenic ... [more ▼]

Proneural proteins play a central role in vertebrate neurogenesis, but little is known of the genes that they regulate and of the factors that interact with proneural proteins to activate a neurogenic program. Here, we demonstrate that the proneural protein Mash1 and the POU proteins Brn1 and Brn2 interact on the promoter of the Notch ligand Delta1 and synergistically activate Delta1 transcription, a key step in neurogenesis. Overexpression experiments in vivo indicate that Brn2, like Mash1, regulates additional aspects of neurogenesis, including the division of progenitors and the differentiation and migration of neurons. We identify by in silico screening a number of additional candidate target genes, which are recognized by Mash1 and Brn proteins through a DNA-binding motif similar to that found in the Delta1 gene and present a broad range of activities. We thus propose that Mash1 synergizes with Brn factors to regulate multiple steps of neurogenesis. [less ▲]

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See detailA role for proneural genes in the maturation of cortical progenitor cells.
Britz, Olivier; Mattar, Pierre; Nguyen, Laurent ULg et al

in Cerebral Cortex (2006), 16 Suppl 1

We showed previously that the proneural genes Neurogenin1 (Ngn1) and Ngn2 are required to specify the phenotypes of early- and not late-born neurons in the neocortex, acting in part through repression of ... [more ▼]

We showed previously that the proneural genes Neurogenin1 (Ngn1) and Ngn2 are required to specify the phenotypes of early- and not late-born neurons in the neocortex, acting in part through repression of Mash1, a third cortically expressed proneural gene. The precise timing of Ngn1/2 specification activity was unexpected given these genes are expressed throughout cortical development, prompting us to search for a later function. Here we reveal that Ngn2 and Mash1 are expressed in a dynamic fashion, acquiring a cell cycle-biased, nonoverlapping distribution, with preferential expression in prospective basal progenitors, during mid corticogenesis. We also identified a new function for Ngn2 during this latter period, demonstrating that it is required to regulate the transit of cortical progenitors from the ventricular zone (VZ) to the subventricular zone. Notably, Ngn2 regulates progenitor maturation at least in part through repression of Mash1 as misexpression of Mash1 strongly enhanced progenitor cell exit from the VZ. Significantly, the ability of Mash1 to promote progenitor cell maturation occurred independently of its ability to respecify cortical cells and is thus a novel function for Mash1. Taken together, these data support a model whereby Ngn2 and Mash1 function together to regulate the zonal distribution of progenitors in the developing neocortex. [less ▲]

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See detailImpact d’un sport-études sur la vie d’un établissement scolaire
Frédéric, Olivier; Louis, Lionel; Cloes, Marc ULg

in Carlier, Ghislain; Bouthier, Daniel; Bui-Xuân, G. (Eds.) Intervenir en éducation physique et en sport. Recherches actuelles (2006)

Nous nous proposons d’étudier le cas d’un établissement secondaire dans lequel a été créée une section sport-études et d’analyser l’impact social de cette filière d’études dans l’école en question en ... [more ▼]

Nous nous proposons d’étudier le cas d’un établissement secondaire dans lequel a été créée une section sport-études et d’analyser l’impact social de cette filière d’études dans l’école en question en recueillant, auprès des différents acteurs de la structure, des informations concernant les objectifs associés au sport-études, les motifs de participation, les relations entre les différents acteurs du site, la perception du sport-études et la perception du niveau des élèves. Pour d’évidentes raisons de place, nous avons choisi de n’aborder dans cet article que les trois premiers aspects. [less ▲]

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