References of "2006"
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See detailResults towards identifiability properties of biochemical reaction networks
Farina, Marcello; Findeisen, Rolf; Bullinger, Eric ULg et al

in Proc. of the 45th IEEE Conference on Decision and Control, San Diego, USA (2006, December)

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions ... [more ▼]

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions on the biochemical reaction network and on the measured outputs that guarantee identifiability of the parameters. Taking the specific system structure of biochemical reaction networks into account, we derive sufficient conditions for local parameter identifiability based on a suitable system expansion which does not any more directly depend on the parameters. Rather, as shown, the problem of identifiability can be recast as the question of observability of the (parameter free) expanded system. The conditions derived are exemplified considering a simple example [less ▲]

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See detailAutomates et vérification
Wolper, Pierre ULg

in Encyclopédie de l'informatique et des systèmes d'information (2006)

La vérification de programmes consiste à analyser les comportements possibles de programmes en vue de déterminer s’ils seront toujours conformes à ce qui est attendu. Pour ce faire, les caractéristiques ... [more ▼]

La vérification de programmes consiste à analyser les comportements possibles de programmes en vue de déterminer s’ils seront toujours conformes à ce qui est attendu. Pour ce faire, les caractéristiques souhaitées des comportements sont exprimées formellement et confrontées, par des techniques mathématiques rigoureuses, à l’ensemble des comportements du programme à analyser. Dans ce contexte, les automates jouent un triple rôle. Tout d’abord, ils sont fréquemment utilisés en tant que langage de programmation simplifié pour décrire les programmes à analyser. Ensuite, ils servent de formalisme de description de propriétés de comportements, soit directement, soit par traduction à partir d’un langage logique. Finalement, ils s’avèrent très utiles en tant que formalisme de description d’ensembles infinis de valeurs. [less ▲]

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See detailResults of a whole-genome quantitative trait locus scan for growth, carcass composition and meat quality in a porcine four-way cross
Harmegnies, N.; Davin, Fabienne ULg; De Smet, S. et al

in Animal Genetics (2006), 37(6), 543-553

A whole-genome quantitative trait locus (QTL) scan for 31 phenotypes related to growth, carcass composition and meat quality was conducted using 1187 progeny of a commercial four-way cross. Animals were ... [more ▼]

A whole-genome quantitative trait locus (QTL) scan for 31 phenotypes related to growth, carcass composition and meat quality was conducted using 1187 progeny of a commercial four-way cross. Animals were genotyped for 198 microsatellite markers that spanned the entire porcine genome. QTL analysis was conducted to extract information from paternal and maternal meioses separately using a rank-based nonparametric approach for half-sib designs. Nine QTL exceeded genome-wide significance: one QTL affecting growth (average daily gain on SSC1), two QTL influencing carcass composition (fatness on SSC3 and muscle mass on SSC15) and six QTL influencing meat quality (tenderness on SSC4 and SSC14; colour on SSC5, SSC6 and SSCX; and conductivity on SSC16). All but one of these coincided with previously reported QTL. In addition, we present evidence for 78 suggestive QTL with a combined false discovery rate of 40%. [less ▲]

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See detailAutobiographical memory in non-amnesic alcohol-dependent patients
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; Verbanck, Paul et al

in Psychological Medicine (2006), 36(12), 1707-1715

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic ... [more ▼]

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic patients. The purpose of this study was to investigate (a) non-amnesic alcoholics' ability to recall specific autobiographical memories and (b) their subjective experience when they access specific memories.Method. Twenty non-amnesic (without Korsakoff syndrome) recently detoxified alcoholics and 20 healthy controls completed the Autobiographical Memory Test (AMT), which assesses the frequency of specific (versus general) memories recalled in response to cue words, and the Memory Characteristics Questionnaire (MCQ), which assesses subjective experience (e.g. the amount of sensory and contextual details experienced) when remembering specific events.Results. Alcoholic patients recalled specific memories less frequently and general memories more frequently than healthy controls. Nevertheless, when a specific past event was accessed, alcoholic patients subjectively experienced as many sensory and contextual details as controls.Conclusions. These findings suggest that non-amnesic alcoholics have difficulties strategically accessing event-specific autobiographical knowledge, which might result from changes in frontal lobe function that are associated with alcoholism. [less ▲]

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See detailCompte-rendu de l'ouvrage: La Guerre en chansons. Textes réunis par François Genton.
Peere, Isabelle ULg

in Lied und Populäre Kultur = Song and Popular Culture (2006), 50/51

A review of an interdisciplinary and multi-dimensional panorama on the relevance of 'borders' (cultural, political, ideological) in relation to major European social and political events viewed through ... [more ▼]

A review of an interdisciplinary and multi-dimensional panorama on the relevance of 'borders' (cultural, political, ideological) in relation to major European social and political events viewed through the testimonies of French, German, Austrian, Rumanian and Russian song [less ▲]

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See detailComment construire l'identité professionnelle dans les métiers de l'humain ?
Beckers, Jacqueline ULg; Jardon, Dorothée

in Puzzle (2006), 21

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See detailComment je traite ... une grossesse extra-uterine
Degee, S.; Dricot, J. F.; Lamborelle, S. et al

in Revue Médicale de Liège (2006), 61(12), 797-803

Nowadays, the management of ectopic pregnancy should be codified as often as possible. Two types of treatment are possible. One surgical and the other medical. Our study is concerned with a series of 97 ... [more ▼]

Nowadays, the management of ectopic pregnancy should be codified as often as possible. Two types of treatment are possible. One surgical and the other medical. Our study is concerned with a series of 97 patients hospitalized for suspicion of ectopic pregnancy for whom the risk factors and treatment were analyzed. Our conclusion is that the medical treatment should be more frequently proposed and surgery should prefer the conservative treatment whenever it is still possible. [less ▲]

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See detailIntérêt actuel de l'étude des poisons de flèches : synthèse des connaissances
Philippe, Geneviève ULg; Angenot, Luc ULg

in Etnopharmacologia- Bulletin de la Société Française d'Ethnopharmacologie et de la Société Européenne d'Ethnopharmacologie (2006), (38), 43-49

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See detailConcrete removal techniques: influence on residual cracking and bond strength
Bissonnette, Benoit; Courard, Luc ULg; Vaysburd, Alex et al

in Concrete International (2006), 28(12), 49-55

The aim of concrete surface preparation prior to repair is to obtain a surface with properties close to that of the bulk concrete. In this paper, the results of an investigation intended to evaluate the ... [more ▼]

The aim of concrete surface preparation prior to repair is to obtain a surface with properties close to that of the bulk concrete. In this paper, the results of an investigation intended to evaluate the mechanical degradation induced by different surface preparation techniques are presented. Optical microscope observations clearly show that more cracking is induced with jack-hammers than with the other investigated techniques and that the cracking density increases with the hammer weight. While more information is needed to evaluate quantitatively the effects of concrete removal operations, it appears from the reported results that techniques such as sandblasting, scarifying and water jetting are preferable, as they clearly leave much less defects in the substrate. [less ▲]

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See detailCrystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study
Maes, D.; Crabeel, M.; Van de Weerdt, Cécile ULg et al

in Acta Crystallographica Section F-Structural Biology and Crystallization Communications (2006), 62(Part 12), 1294-1297

A study is presented on the crystallization of ornithine acetyltransferase from yeast, which catalyzes the fifth step in microbial arginine synthesis. The use of the counter-diffusion technique removes ... [more ▼]

A study is presented on the crystallization of ornithine acetyltransferase from yeast, which catalyzes the fifth step in microbial arginine synthesis. The use of the counter-diffusion technique removes the disorder present in one dimension in crystals grown by either the batch or hanging-drop techniques. This makes the difference between useless crystals and crystals that allow successful determination of the structure of the protein. The crystals belong to space group P4, with unit-cell parameters a = b = 66.98, c = 427.09 angstrom, and a data set was collected to 2.76 angstrom. [less ▲]

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See detailEffect of an intubation dose of rocuronium on Spectral Entropy and Bispectral Index (TM) responses to laryngoscopy during propofol anaesthesia
Hans, Pol ULg; Giwer, Jérôme ULg; Brichant, Jean-François ULg et al

in British Journal of Anaesthesia (2006), 97(6), 842-847

Background. The spectral entropy of the electroencephalogram has been proposed to monitor the depth of anaesthesia. State Entropy (SE) reflects the level of hypnosis. Response Entropy (RE), computed from ... [more ▼]

Background. The spectral entropy of the electroencephalogram has been proposed to monitor the depth of anaesthesia. State Entropy (SE) reflects the level of hypnosis. Response Entropy (RE), computed from electroencephalogram and facial muscle activity, reflects the response to nociceptive stimulation. We evaluated the effect of rocuronium on Bispectral Index (TM) (BIS) and entropy responses to laryngoscopy. Methods. A total of 25 patients were anaesthetized with propofol using a target-controlled infusion. At steady state, they randomly received 0.6 mg kg(-1) rocuronium (R) or saline (S). After 3 min, a 20 s laryngoscopy was applied. BIS, RE and SE were recorded continuously and averaged over 1 min during baseline, at steady state, 2 min after R or S administration (R/S+2) and 0, 1, 2 and 3 min after laryngoscopy (L0, L1, L2, L3). Results. At R/S+2, the RE-SE gradient was higher in Group S than in Group R. Laryngoscopy provoked an increase in BIS, RE and SE. Comparing R/S+2 and L0 values in Groups R and S, BIS increased from 43 (6) to 49 (8) and 42 (9) to 51 (15), SE increased from 43 (7) to 50 (8) and 41 (10) to 55 (12), and RE increased from 46 (8) to 54 (9) and 47 (12) to 66 (15), respectively. BIS and SE did not differ between groups. At L0, RE and RE-SE were higher in Group S [66 (15) and 11 (4), respectively] than in Group R [54 (9) and 4 (2), respectively]. Conclusions. Rocuronium alters the RE-SE gradient and the RE and RE-SE responses to laryngoscopy. Muscle relaxation may confound interpretation of entropy monitoring. [less ▲]

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See detailLa presbyphonie - Le vieillissement de la voix
Remacle, Marc; Zaarour, Stéphanie; Soh-Ping, Eng et al

in Klein-Dallant, Carine (Ed.) Voix parlée et chantée (2006)

Les changements causés par le vieillissement se déroulent à un rythme différent pour chaque personne et dépendent de facteurs comme le style de vie, les activités et l'environnement ainsi que des facteurs ... [more ▼]

Les changements causés par le vieillissement se déroulent à un rythme différent pour chaque personne et dépendent de facteurs comme le style de vie, les activités et l'environnement ainsi que des facteurs comme le bagage génétique et l'état de santé.La presbyphonie est le terme employé pour définir le vieillissement de la voix. Elle s'observe le plus souvent après 60 ans et touche les deux sexes. Ce trouble vocal est la conséquence d'altérations morphologiques et fonctionnelles des systèmes pneumo-phono-articulatoires qui résultent d'une modification hormonale (thyroïdienne et sexuelles), d'une altération de l'état musculaire, vasculaire, nerveux ou respiratoire, ou encore d'un manque d'exercice vocal. [less ▲]

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See detailA long-term, open-label trial of the safety and efficacy of etanercept (Enbrel) in patients with rheumatoid arthritis not treated with other disease-modifying antirheumatic drugs
Klareskog, L.; Gaubitz, M.; Rodriguez-Valverde, V. et al

in Annals of the Rheumatic Diseases (2006), 65(12), 1578-1584

Objective: To evaluate the long-term safety and efficacy of etanercept in patients with rheumatoid arthritis. Methods: 549 patients entered this 5-year, open-label extension study and received etanercept ... [more ▼]

Objective: To evaluate the long-term safety and efficacy of etanercept in patients with rheumatoid arthritis. Methods: 549 patients entered this 5-year, open-label extension study and received etanercept 25 mg twice weekly. All patients showed inadequate responses to disease-modifying antirheumatic drugs before entry into the double-blind studies. Safety assessments were carried out at regular intervals. Primary efficacy end points were the numbers of painful and swollen joints; secondary variables included American College of Rheumatology (ACR) response rate, Disease Activity Score and acute-phase reactants. Efficacy was analysed using the last-observation-carried-forward approach. Results: Of the 549 patients enrolled in the open-label trial, 467 (85%), 414 (75%) and 371 (68%) completed 1, 2 and 3 years, respectively; 363 (66%) remained in the study at the time of this analysis. A total exposure of 1498 patient-years, including the double-blind study, was accrued. In the open-label trial, withdrawals for efficacy-related and safety-related reasons were 11% and 13%, respectively. Frequent adverse events included upper respiratory infections, flu syndrome, rash and injection-site reactions. Rates of serious infections and malignancies remained unchanged over the course of the study; there were no reports of patients with central demyelinating disease or serious blood dyscrasias. After 3 years, ACR20, ACR50 and ACR70 response rates were 78%, 51% and 27%, respectively. The Disease Activity Score score was reduced to 3.0 at 3 months and 2.6 at 3 years from 5.1. A sustained improvement was found in Health Assessment Questionnaire scores throughout the 3-year time period. Conclusion: After 3 years of treatment, etanercept showed sustained efficacy and a favourable safety profile. [less ▲]

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See detailUpdate on field experiments and description of the groundwater flow and transport model for the Flémalle cokery site
Batlle-Aguilar, Jordi; Brouyère, Serge ULg

Report (2006)

This deliverable summarises all the hydrogeological experiments performed in the scope of the AquaTerra project by HGULg in the Flémalle test site. These experiments consisted in various hydraulic tests ... [more ▼]

This deliverable summarises all the hydrogeological experiments performed in the scope of the AquaTerra project by HGULg in the Flémalle test site. These experiments consisted in various hydraulic tests and tracer tests performed to quantify hydrodynamic and hydrodispersive properties of the alluvial gravel aquifer and to evaluate groundwater fluxes in the aquifer and at the aquifer-river interface. First steps in groundwater modelling are also presented. [less ▲]

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See detailLe genotypage RHD foetal sur sang maternel dans le suivi prenatal des patientes Rh D negatif
Dricot, J. F.; Minon, J. M.; Schaaps, Jean-Pierre ULg et al

in Revue Médicale de Liège (2006), 61(12), 820-6

Since the beginning of RHD genotyping in maternal plasma, no Rh D positive baby was diagnosed RHD negative in our institution. Genotyping from circulating DNA in maternal plasma is as efficient as ... [more ▼]

Since the beginning of RHD genotyping in maternal plasma, no Rh D positive baby was diagnosed RHD negative in our institution. Genotyping from circulating DNA in maternal plasma is as efficient as genotyping on amniocyts but without the associated risks. We propose a prophylactic injection based on fetal genotyping RHD in maternal blood with 300 microg anti-D immunoglobulin at 28 weeks of amenhorrea in all of Rh D negative pregnant women whitch fetuses positive RHD. [less ▲]

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See detailClosed-Loop Learning of Visual Control Policies
JODOGNE, Sébastien ULg

Doctoral thesis (2006)

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See detailIntra-arterial thrombolysis of thrombosed popliteal artery aneurysm. A series of six cases
Van Damme, Hendrik ULg; Trotteur, Geneviève ULg; Kerzmann, Arnaud ULg et al

in Acta Chirurgica Belgica (2006), 106(6), 679-683

Aim of the study : To evaluate the role of perioperative, catheter-guided fibrinolysis in the management of thrombosed popliteal artery aneurysms. Material : From 1990 to 2005, six patients suffering ... [more ▼]

Aim of the study : To evaluate the role of perioperative, catheter-guided fibrinolysis in the management of thrombosed popliteal artery aneurysms. Material : From 1990 to 2005, six patients suffering subacute limb ischemia, secondary to thrombosis of a popliteal artery aneurysm, benefited selective intra-arterial fibrinolysis, followed by subsequent aneurysm exclusion and bypass grafting. This represents ten percent of all popliteal aneurysms operated on in that time period and 28% of all thrombosed popliteal artery aneurysms. Results : The lytic procedure was successful in all cases, restituting patency in two (n = 3), one (n = 2) or all (n = 1) crural arteries. The venous bypass graft remained patent in all but one patient. In one patient, the graft occluded at 10 months without limb loss. This outcome compares more favorable than the result obtained with emergent surgery alone for thrombosed popliteal artery aneurysms with profound limb ischemia (eight patients, of whom one required amputation at day 5 and one lost his limb at nine months following graft thrombosis). Conclusion : Preoperative intra-arterial lytic therapy, in the setting of subacute limb ischemia caused by thrombosis of a popliteal artery aneurysm, can be considered as safe and effective. [less ▲]

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See detailPolyphasic study of Antarctic cyanobacterial strains
Taton, A.; Grubisic, Stana ULg; Ertz, D. et al

in Journal of Phycology (2006), 42(6), 1257-1270

We isolated 59 strains of cyanobacteria from the benthic microbial mats of 23 Antarctic lakes, from five locations in two regions, in order to characterize their morphological and genotypic diversity. On ... [more ▼]

We isolated 59 strains of cyanobacteria from the benthic microbial mats of 23 Antarctic lakes, from five locations in two regions, in order to characterize their morphological and genotypic diversity. On the basis of their morphology, the cyanobacteria were assigned to 12 species that included four Antarctic endemic taxa. Sequences of the ribosomal RNA gene were determined for 56 strains. In general, the strains closely related at the 16S rRNA gene level belonged to the same morphospecies. Nevertheless, divergences were observed concerning the diversity in terms of species richness, novelty, and geographical distribution. For the 56 strains, 21 operational taxonomic units (OTUs, defined as groups of partial 16S rRNA gene sequences with more than 97.5% similarity) were found, including nine novel and three exclusively Antarctic OTUs. Sequences of Petalonema cf. involvens and Chondrocystis sp. were determined for the first time. The internally transcribed spacer (ITS) between the 16S and the 23S rRNA genes was sequenced for 33 strains, and similar groupings were observed with the 16S rRNA gene and the ITS, even when the strains were derived from different lakes and regions. In addition, 48 strains were screened for antimicrobial and cytotoxic activities, and 17 strains were bioactive against the gram-positive Staphylococcus aureus, or the fungi Aspergillus fumigatus and Cryptococcus neoformans. The bioactivities were not in coincidence with the phylogenetic relationships, but rather were specific to certain strains. [less ▲]

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See detailUn ongle d'inclusion: une complication de la cure chirurgicale d'ongle incarne selon la technique de Zadik
Vanhooteghem, Olivier ULg; Henrijean, A.; André, Jean-François ULg et al

in Annales de Dermatologie et de Vénéréologie (2006), 133(12), 1009-10

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