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See detailAutobiographical memory in non-amnesic alcohol-dependent patients
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; Verbanck, Paul et al

in Psychological Medicine (2006), 36(12), 1707-1715

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic ... [more ▼]

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic patients. The purpose of this study was to investigate (a) non-amnesic alcoholics' ability to recall specific autobiographical memories and (b) their subjective experience when they access specific memories.Method. Twenty non-amnesic (without Korsakoff syndrome) recently detoxified alcoholics and 20 healthy controls completed the Autobiographical Memory Test (AMT), which assesses the frequency of specific (versus general) memories recalled in response to cue words, and the Memory Characteristics Questionnaire (MCQ), which assesses subjective experience (e.g. the amount of sensory and contextual details experienced) when remembering specific events.Results. Alcoholic patients recalled specific memories less frequently and general memories more frequently than healthy controls. Nevertheless, when a specific past event was accessed, alcoholic patients subjectively experienced as many sensory and contextual details as controls.Conclusions. These findings suggest that non-amnesic alcoholics have difficulties strategically accessing event-specific autobiographical knowledge, which might result from changes in frontal lobe function that are associated with alcoholism. [less ▲]

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See detailBuilding EnCOrE : Encyclopédie de Chimie Organique Electronique
Colaux, Catherine ULg; Seleck, Caroline; Henry, Julie et al

Poster (2006, December)

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See detailAutomates et vérification
Wolper, Pierre ULg

in Encyclopédie de l'informatique et des systèmes d'information (2006)

La vérification de programmes consiste à analyser les comportements possibles de programmes en vue de déterminer s’ils seront toujours conformes à ce qui est attendu. Pour ce faire, les caractéristiques ... [more ▼]

La vérification de programmes consiste à analyser les comportements possibles de programmes en vue de déterminer s’ils seront toujours conformes à ce qui est attendu. Pour ce faire, les caractéristiques souhaitées des comportements sont exprimées formellement et confrontées, par des techniques mathématiques rigoureuses, à l’ensemble des comportements du programme à analyser. Dans ce contexte, les automates jouent un triple rôle. Tout d’abord, ils sont fréquemment utilisés en tant que langage de programmation simplifié pour décrire les programmes à analyser. Ensuite, ils servent de formalisme de description de propriétés de comportements, soit directement, soit par traduction à partir d’un langage logique. Finalement, ils s’avèrent très utiles en tant que formalisme de description d’ensembles infinis de valeurs. [less ▲]

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See detailAdvances in immunoproteomics for serological characterization of microbial antigens
Falisse-Poirier, Nandini; Ruelle, Virginie ULg; Elmoualij, Benaïssa ULg et al

in Journal of Microbiological Methods (2006), 67(3), 593-596

We propose a multi-dimensional strategy, associating immunodetection to a protein fractionating two-dimensional liquid chromatography tool, for serological characterization of microbial antigens. The ... [more ▼]

We propose a multi-dimensional strategy, associating immunodetection to a protein fractionating two-dimensional liquid chromatography tool, for serological characterization of microbial antigens. The originality of such immunoproteomic approaches resides in their application in large-scale studies for rapid serotyping of micro-organisms, evaluation of immunomes and could be proposed in the development and monitoring of vaccines. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailCompte-rendu de l'ouvrage: La Guerre en chansons. Textes réunis par François Genton.
Peere, Isabelle ULg

in Lied und Populäre Kultur = Song and Popular Culture (2006), 50/51

A review of an interdisciplinary and multi-dimensional panorama on the relevance of 'borders' (cultural, political, ideological) in relation to major European social and political events viewed through ... [more ▼]

A review of an interdisciplinary and multi-dimensional panorama on the relevance of 'borders' (cultural, political, ideological) in relation to major European social and political events viewed through the testimonies of French, German, Austrian, Rumanian and Russian song [less ▲]

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See detailResults towards identifiability properties of biochemical reaction networks
Farina, Marcello; Findeisen, Rolf; Bullinger, Eric ULg et al

in Proc. of the 45th IEEE Conference on Decision and Control, San Diego, USA (2006, December)

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions ... [more ▼]

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions on the biochemical reaction network and on the measured outputs that guarantee identifiability of the parameters. Taking the specific system structure of biochemical reaction networks into account, we derive sufficient conditions for local parameter identifiability based on a suitable system expansion which does not any more directly depend on the parameters. Rather, as shown, the problem of identifiability can be recast as the question of observability of the (parameter free) expanded system. The conditions derived are exemplified considering a simple example [less ▲]

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See detailAssessment of trophic relationships between symbiotic tropical ophiuroids using C and N stable isotope analysis
Fourgon, Didier; Lepoint, Gilles ULg; Eeckhaut, Igor

in Journal of the Marine Biological Association of the United Kingdom (2006), 86(6), 1443-1447

Analyses of the natural abundance of carbon and nitrogen stable isotopes were performed to investigate the feeding habits of two ophiurolds, Ophiomastix venosa and Ophiocoma scolopendrina, and to assess ... [more ▼]

Analyses of the natural abundance of carbon and nitrogen stable isotopes were performed to investigate the feeding habits of two ophiurolds, Ophiomastix venosa and Ophiocoma scolopendrina, and to assess the potential benefit obtained by the symbiotic Ophiomastix venosa juveniles. A tracer experiment was also carried Out to clarify the contribution of algae to the nitrogen uptake amongst the tested ophiurolds. Our results suggest that Ophiocoma scolopendrina adults occupy a higher position in the food web than Ophiomastix venosa and mainly feed on neuston. In contrast, O. venosa adults feed on the alga Sargassum densifolium, and on organic matter associated with sediment. Free juveniles and symbiotic juveniles of O. venosa have intermediate PC values between both adult species. The high proportion of C-13 in the symbiotic juveniles compared to the one in their conspecific adults indicates that their diet slightly differs from the latter and is closer to that of Ophiocoma scolopendrina. This raises the hypothesis that symbiotic juveniles steal neuston front their associated host, O. scolopendrina. [less ▲]

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See detailAn introduction to robotics - mechanical aspects
Duysinx, Pierre ULg; Bruls, Olivier ULg; Géradin, Michel ULg

Learning material (2006)

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See detailComment construire l'identité professionnelle dans les métiers de l'humain ?
Beckers, Jacqueline ULg; Jardon, Dorothée

in Puzzle (2006), 21

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See detailTranscriptional regulation of the mouse doublecortin gene in differentiating neurons
Plumier, Jean-Christophe ULg; Muller, Marc ULg; Rogister, Bernard ULg et al

in International Journal of Developmental Neuroscience (2006, December), 24(8), 535

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See detailComment je traite ... une grossesse extra-uterine
Degee, S.; Dricot, J. F.; Lamborelle, S. et al

in Revue Médicale de Liège (2006), 61(12), 797-803

Nowadays, the management of ectopic pregnancy should be codified as often as possible. Two types of treatment are possible. One surgical and the other medical. Our study is concerned with a series of 97 ... [more ▼]

Nowadays, the management of ectopic pregnancy should be codified as often as possible. Two types of treatment are possible. One surgical and the other medical. Our study is concerned with a series of 97 patients hospitalized for suspicion of ectopic pregnancy for whom the risk factors and treatment were analyzed. Our conclusion is that the medical treatment should be more frequently proposed and surgery should prefer the conservative treatment whenever it is still possible. [less ▲]

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See detailIntérêt actuel de l'étude des poisons de flèches : synthèse des connaissances
Philippe, Geneviève ULg; Angenot, Luc ULg

in Etnopharmacologia- Bulletin de la Société Française d'Ethnopharmacologie et de la Société Européenne d'Ethnopharmacologie (2006), (38), 43-49

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See detailConcrete removal techniques: influence on residual cracking and bond strength
Bissonnette, Benoit; Courard, Luc ULg; Vaysburd, Alex et al

in Concrete International (2006), 28(12), 49-55

The aim of concrete surface preparation prior to repair is to obtain a surface with properties close to that of the bulk concrete. In this paper, the results of an investigation intended to evaluate the ... [more ▼]

The aim of concrete surface preparation prior to repair is to obtain a surface with properties close to that of the bulk concrete. In this paper, the results of an investigation intended to evaluate the mechanical degradation induced by different surface preparation techniques are presented. Optical microscope observations clearly show that more cracking is induced with jack-hammers than with the other investigated techniques and that the cracking density increases with the hammer weight. While more information is needed to evaluate quantitatively the effects of concrete removal operations, it appears from the reported results that techniques such as sandblasting, scarifying and water jetting are preferable, as they clearly leave much less defects in the substrate. [less ▲]

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See detailCrystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study
Maes, D.; Crabeel, M.; Van de Weerdt, Cécile ULg et al

in Acta Crystallographica Section F-Structural Biology and Crystallization Communications (2006), 62(Part 12), 1294-1297

A study is presented on the crystallization of ornithine acetyltransferase from yeast, which catalyzes the fifth step in microbial arginine synthesis. The use of the counter-diffusion technique removes ... [more ▼]

A study is presented on the crystallization of ornithine acetyltransferase from yeast, which catalyzes the fifth step in microbial arginine synthesis. The use of the counter-diffusion technique removes the disorder present in one dimension in crystals grown by either the batch or hanging-drop techniques. This makes the difference between useless crystals and crystals that allow successful determination of the structure of the protein. The crystals belong to space group P4, with unit-cell parameters a = b = 66.98, c = 427.09 angstrom, and a data set was collected to 2.76 angstrom. [less ▲]

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See detailEffect of an intubation dose of rocuronium on Spectral Entropy and Bispectral Index (TM) responses to laryngoscopy during propofol anaesthesia
Hans, Pol ULg; Giwer, Jérôme ULg; Brichant, Jean-François ULg et al

in British Journal of Anaesthesia (2006), 97(6), 842-847

Background. The spectral entropy of the electroencephalogram has been proposed to monitor the depth of anaesthesia. State Entropy (SE) reflects the level of hypnosis. Response Entropy (RE), computed from ... [more ▼]

Background. The spectral entropy of the electroencephalogram has been proposed to monitor the depth of anaesthesia. State Entropy (SE) reflects the level of hypnosis. Response Entropy (RE), computed from electroencephalogram and facial muscle activity, reflects the response to nociceptive stimulation. We evaluated the effect of rocuronium on Bispectral Index (TM) (BIS) and entropy responses to laryngoscopy. Methods. A total of 25 patients were anaesthetized with propofol using a target-controlled infusion. At steady state, they randomly received 0.6 mg kg(-1) rocuronium (R) or saline (S). After 3 min, a 20 s laryngoscopy was applied. BIS, RE and SE were recorded continuously and averaged over 1 min during baseline, at steady state, 2 min after R or S administration (R/S+2) and 0, 1, 2 and 3 min after laryngoscopy (L0, L1, L2, L3). Results. At R/S+2, the RE-SE gradient was higher in Group S than in Group R. Laryngoscopy provoked an increase in BIS, RE and SE. Comparing R/S+2 and L0 values in Groups R and S, BIS increased from 43 (6) to 49 (8) and 42 (9) to 51 (15), SE increased from 43 (7) to 50 (8) and 41 (10) to 55 (12), and RE increased from 46 (8) to 54 (9) and 47 (12) to 66 (15), respectively. BIS and SE did not differ between groups. At L0, RE and RE-SE were higher in Group S [66 (15) and 11 (4), respectively] than in Group R [54 (9) and 4 (2), respectively]. Conclusions. Rocuronium alters the RE-SE gradient and the RE and RE-SE responses to laryngoscopy. Muscle relaxation may confound interpretation of entropy monitoring. [less ▲]

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See detailLa presbyphonie - Le vieillissement de la voix
Remacle, Marc; Zaarour, Stéphanie; Soh-Ping, Eng et al

in Klein-Dallant, Carine (Ed.) Voix parlée et chantée (2006)

Les changements causés par le vieillissement se déroulent à un rythme différent pour chaque personne et dépendent de facteurs comme le style de vie, les activités et l'environnement ainsi que des facteurs ... [more ▼]

Les changements causés par le vieillissement se déroulent à un rythme différent pour chaque personne et dépendent de facteurs comme le style de vie, les activités et l'environnement ainsi que des facteurs comme le bagage génétique et l'état de santé.La presbyphonie est le terme employé pour définir le vieillissement de la voix. Elle s'observe le plus souvent après 60 ans et touche les deux sexes. Ce trouble vocal est la conséquence d'altérations morphologiques et fonctionnelles des systèmes pneumo-phono-articulatoires qui résultent d'une modification hormonale (thyroïdienne et sexuelles), d'une altération de l'état musculaire, vasculaire, nerveux ou respiratoire, ou encore d'un manque d'exercice vocal. [less ▲]

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See detailA long-term, open-label trial of the safety and efficacy of etanercept (Enbrel) in patients with rheumatoid arthritis not treated with other disease-modifying antirheumatic drugs
Klareskog, L.; Gaubitz, M.; Rodriguez-Valverde, V. et al

in Annals of the Rheumatic Diseases (2006), 65(12), 1578-1584

Objective: To evaluate the long-term safety and efficacy of etanercept in patients with rheumatoid arthritis. Methods: 549 patients entered this 5-year, open-label extension study and received etanercept ... [more ▼]

Objective: To evaluate the long-term safety and efficacy of etanercept in patients with rheumatoid arthritis. Methods: 549 patients entered this 5-year, open-label extension study and received etanercept 25 mg twice weekly. All patients showed inadequate responses to disease-modifying antirheumatic drugs before entry into the double-blind studies. Safety assessments were carried out at regular intervals. Primary efficacy end points were the numbers of painful and swollen joints; secondary variables included American College of Rheumatology (ACR) response rate, Disease Activity Score and acute-phase reactants. Efficacy was analysed using the last-observation-carried-forward approach. Results: Of the 549 patients enrolled in the open-label trial, 467 (85%), 414 (75%) and 371 (68%) completed 1, 2 and 3 years, respectively; 363 (66%) remained in the study at the time of this analysis. A total exposure of 1498 patient-years, including the double-blind study, was accrued. In the open-label trial, withdrawals for efficacy-related and safety-related reasons were 11% and 13%, respectively. Frequent adverse events included upper respiratory infections, flu syndrome, rash and injection-site reactions. Rates of serious infections and malignancies remained unchanged over the course of the study; there were no reports of patients with central demyelinating disease or serious blood dyscrasias. After 3 years, ACR20, ACR50 and ACR70 response rates were 78%, 51% and 27%, respectively. The Disease Activity Score score was reduced to 3.0 at 3 months and 2.6 at 3 years from 5.1. A sustained improvement was found in Health Assessment Questionnaire scores throughout the 3-year time period. Conclusion: After 3 years of treatment, etanercept showed sustained efficacy and a favourable safety profile. [less ▲]

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See detailLe genotypage RHD foetal sur sang maternel dans le suivi prenatal des patientes Rh D negatif
Dricot, J. F.; Minon, J. M.; Schaaps, Jean-Pierre ULg et al

in Revue Médicale de Liège (2006), 61(12), 820-6

Since the beginning of RHD genotyping in maternal plasma, no Rh D positive baby was diagnosed RHD negative in our institution. Genotyping from circulating DNA in maternal plasma is as efficient as ... [more ▼]

Since the beginning of RHD genotyping in maternal plasma, no Rh D positive baby was diagnosed RHD negative in our institution. Genotyping from circulating DNA in maternal plasma is as efficient as genotyping on amniocyts but without the associated risks. We propose a prophylactic injection based on fetal genotyping RHD in maternal blood with 300 microg anti-D immunoglobulin at 28 weeks of amenhorrea in all of Rh D negative pregnant women whitch fetuses positive RHD. [less ▲]

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See detailClosed-Loop Learning of Visual Control Policies
JODOGNE, Sébastien ULg

Doctoral thesis (2006)

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