References of "2006"
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See detailResults towards identifiability properties of biochemical reaction networks
Farina, Marcello; Findeisen, Rolf; Bullinger, Eric ULg et al

in Proc. of the 45th IEEE Conference on Decision and Control, San Diego, USA (2006, December)

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions ... [more ▼]

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions on the biochemical reaction network and on the measured outputs that guarantee identifiability of the parameters. Taking the specific system structure of biochemical reaction networks into account, we derive sufficient conditions for local parameter identifiability based on a suitable system expansion which does not any more directly depend on the parameters. Rather, as shown, the problem of identifiability can be recast as the question of observability of the (parameter free) expanded system. The conditions derived are exemplified considering a simple example [less ▲]

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See detailA contribution to the audit of an air-conditioning system: modeling, simulation and benchmarking
Adam, Christophe; Andre, Philippe ULg; Hannay, Cleide et al

(2006, December)

This paper intends to show how benchmarks can help in the audit of a HVAC system and how these benchmarks can be generated. The work presented is part of the European “AUDITAC” project. How can an auditor ... [more ▼]

This paper intends to show how benchmarks can help in the audit of a HVAC system and how these benchmarks can be generated. The work presented is part of the European “AUDITAC” project. How can an auditor declare that a given HVAC is “consuming too much”? He can’t make any judgment, if not having some reference, i.e. some “benchmarks” available. Focus is given here to cooling regime, but even then, heating cannot be forgotten (for example, the remaining heating demand can be satisfied thanks some recovery on the condensers of the chillers). The dramatic question is: what should be the consumption(s) for such a building, in such a climate, with such occupancy, such internal loads and such actual indoor environment? Better than to look for a (very hypothetical) global weather index, similar to heating degree-days, it seems more rational to run a simulation model on a few thousands of hours, corresponding to one (or to several) cooling season(s). Current performances of simulation tools make this approach very expedient. The climate can then be considered as it is, without any simplification. The main simplification is still welcome on the system (building + HVAC) side, in order to get calculation robustness, easy understanding and easy parameter identification. In this perspective, the building has to be subdivided in a very limited number of zones and only a few components of the HVAC system have to be included in the simulation model, with as simple as possible control strategies. [less ▲]

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See detailCost estimates of brain disorders in Belgium
Schoenen, Jean ULg; Gianni, F.; Schretlen, L. et al

in Acta Neurologica Belgica (2006), 106(4), 208-214

This article presents the data on cost of the major brain disorders in Belgium which were retrieved from "Cost of Disorders of the Brain in Europe" study sponsored by the European Brain Council and ... [more ▼]

This article presents the data on cost of the major brain disorders in Belgium which were retrieved from "Cost of Disorders of the Brain in Europe" study sponsored by the European Brain Council and performed by Stockholm Health Economics. The disorders selected were : addiction, depression, anxiety disorders, brain tumours, dementia, epilepsy, migraine and other headaches, multiple sclerosis, Parkinson's disease, psychotic disorders, stroke and trauma. Figures for prevalence of disorders and direct medical, direct non-medical and indirect costs are based on data coming from available electronic data bases, or when missing for Belgium, best possible estimates or extrapolated data were used. All economic data were transformed to E's for 2004 and adjusted for purchasing power parity (PPP). The results show that the total number of people with any brain disorder in Belgium amounts to 2,9 million in 2004, the most prevalent being anxiety disorders 1.1 million, migraine 860 000, addiction (any) 800.000 and depression 500.000 cases. The total cost of all included brain disorders in Belgium was estimated at 10.6 billion Euros. Most costly per case are brain tumours, multiple sclerosis, stroke and dementia. Because of their higher prevalence, however, depression, dementia, addiction, anxiety disorders and migraine have the highest total costs. Taken together, brain disorders consume 4% of the gross national product and cost each citizen of Belgium E 1029 per year The drug costs for brain disorders constitute only 10% of the total drug market in Belgium, and only 4% of the total cost of brain disorders in Belgium. This should be compared to the cost estimates and to a previous study which showed that brain disorders are responsible for 35% of the total burden of all disorders in Europe. This study suggests therefore that the direct healthcare resources, including expenses for drug therapies, allocated to brain disorders in Belgium are not leveled to the indirect costs and burden of these disorders. A comparison with data available from a direct prospective study in demented Belgian patients suggests that the mathematical estimates presented here reflect quite accurately the real average cost for dementia, although there are large variations depending on disease severity. As, in addition, subjects with brain disorders face collateral costs which have not been taken into account and may vary between countries, it seems worthwhile to conduct, in cooperation with patients associations, a complementary survey in the Belgian ecosystem to establish the cost profile of representative patients for the major brain disorders. Such a survey is being organized by a task force of the Belgian Brain Council. [less ▲]

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See detailFrom model validation to production of reference simulations: how to increase reliability and applicability of building and HVAC simulation models
Adam, Christophe; Andre, Philippe ULg; Georges, Bernard ULg et al

(2006, December)

Validation of simulation models appears from a long time as a key issue in order to promote a more intensive and more efficient use of simulation models in the field of building and HVAC simulation. IEA ... [more ▼]

Validation of simulation models appears from a long time as a key issue in order to promote a more intensive and more efficient use of simulation models in the field of building and HVAC simulation. IEA Annex 34/43 originally targeted a number of specific applications where a more advanced validation was required: ground coupling problems, multizone building, shading, day lighting and cooling load interaction, HVAC components and ventilated facades. These validation exercises were built on the large methodological experience obtained in previous projects and address sometimes very fundamental problems of heat transfer in buildings. Consulting engineers and practitioners might see these exercises as a bit too far from their objectives and it is the reason why an additional activity was proposed with the specific aim of producing, based upon the results of the validation of models, a set of reference simulations. These applications cover a range of building types (residential, commercial) and systems (production, distribution emission) and run in a variety of climates. The paper will describe how models dedicated to these applications were developed, starting from validation results, going through the selection and consolidation of simulation hypothesises and ending with a number that might be considered as reference for the concerned applications. The paper will concentrate on models required by a residential building application (multizone building equipped with a heat pump or a condensing boiler). Simulations make use of both EES and TRNSYS software and both software are applied in parallel as far as possible in the different applications in order to get a better judgment of their potential advantages and drawbacks. The use of reference simulations in view of qualifying normative methods currently in development in the frame of the European Energy Performance in Buildings Directive is also addressed and demonstrated in the paper. [less ▲]

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See detailTrou Al'Wesse, Belgium
Miller, Rebecca ULg; Stewart, John

in Mesolithic Miscellany (2006), 18(1), 2

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See detailMicro-macro mechanical modeling of bone-implant interface by means of the homogenization theory
Amor, Nadia; Van Cleynenbreugel, Tim; Geris, Liesbet ULg et al

Poster (2006, December)

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See detailLe cas clinique du mois. Syndrome malin des neuroleptiques et paralysie generale
Foatelli, F. M.; gernay, p; Lievens, Isabelle ULg et al

in Revue Médicale de Liège (2006), 61(12), 807-11

Described in 1960 by Jean Delay in relation to the use of haloperidol, neuroleptic malignant syndrome remains relatively rare, and poorly known by the medical profession. The emergence of the atypical ... [more ▼]

Described in 1960 by Jean Delay in relation to the use of haloperidol, neuroleptic malignant syndrome remains relatively rare, and poorly known by the medical profession. The emergence of the atypical antipsychotic agents and preventive measures which have become general in recent years in hospital departments using dopamine receptor antagonists has not altered the prognosis, which remains potentially fatal in approximately a quarter of cases. This article proposes a descriptive summary of this syndrome in terms of clinical and biological diagnostics as well as of evolution, epidemiology, differential diagnosis and treatment. It describes the case of a patient affected by general paralysis having developed a neuroleptic malignant syndrome, thus the hypothesis what the neuroleptic malignant syndrome preferentially arises in subjects having underlying organic or metabolic problems and provides food for thought regarding the main medical and psychiatric overlaps, the use of dopaminergic agents and the behaviour to be adopted when dealing with a patient presenting with inaugural psychiatric symptomatology. [less ▲]

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See detailSurgical treatment of thoraco-abdominal and low thoracic aneurysms of the aorta. One single center experience over ten years
El Arid, J.-M.; CREEMERS, Etienne ULg; Limet, Raymond ULg

in Acta Chirurgica Belgica (2006), 106(6), 669-674

This work presents the results of surgery in thoraco-abdominal aortic aneurysms (TAA) and thoracic descending aortic aneurysms (TDA) in one single center between January 1rst, 1996 and December 31, 2005 ... [more ▼]

This work presents the results of surgery in thoraco-abdominal aortic aneurysms (TAA) and thoracic descending aortic aneurysms (TDA) in one single center between January 1rst, 1996 and December 31, 2005. It concerns open surgery in 42 and endovascular procedures in ten patients. Forty two patients (11 TDA and 31 TAA (4 type I, 12 type II, 6 type III and 9 type IV)) define the open surgery series. Twenty six patients were operated on elective basis and 16 patients in emergency condition. Surgical correction was made under partial cardio-pulmonary bypass (PCPB) in 70% of cases via femoral vessels; most significant intercostal arteries were reimplanted and cerebro-spinal fluid (CSF) drainage used in half of the cases. Operative mortality was zero in the elective group (0/26) and attained 19% in the emergent group (3/16). Mortality was linked to cerebrovascular accidents (CVA) in two cases and post-pump left lung hemorrhagic intarction in one case. The paraplegia accounts 2/26 in the elective group and one in the emergent group (1/16). That is 7.1% in both groups. At the end of five years, survival is 66% in elective group and 74% in the emergency group. Ten patients (5 TDA and 5 TAA (2 type I, 3 type III)) were treated endovascularly. Operative mortality and postoperative paraplegia were nil. [less ▲]

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See detailEntre méfiance et intégration. Les germanophones dans l'armée belge (1920-1955)
Brüll, Christoph ULg

in Cahiers Belges d'Histoire Militaire (2006), 4

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See detailThe effects of angry and happy expressions on recognition memory for unfamiliar faces in delusion-prone individuals
Laroi, Frank ULg; D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg

in Journal of Behavior Therapy and Experimental Psychiatry (2006), 37(4), 271-282

Numerous studies suggest a cognitive bias for threat-related material in delusional ideation. However, few studies have examined this bias using a memory task. We investigated the influence of delusion ... [more ▼]

Numerous studies suggest a cognitive bias for threat-related material in delusional ideation. However, few studies have examined this bias using a memory task. We investigated the influence of delusion-proneness on identity and expression memory for angry and happy faces. Participants high and low in delusion-proneness were presented with happy and angry faces and were later asked to recognise the same faces displaying a neutral expression. They also had to remember what the initial expressions of the faces had been. Remember/know/guess judgments were asked for both identity and expression memory. Results showed that delusion-prone participants better recognised the identity of angry faces compared to non-delusional participants. Also, this difference between the two groups was mainly due to a greater number of remember responses in delusion-prone participants. These findings extend previous studies by showing that delusions are associated with a memory bias for threat-related stimuli. [less ▲]

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See detailInżyneria powierzchni betonu. Część 2. Wpływ obrobki na powstawanie rys
Courard, Luc ULg; Garbacz, Andrzej; Nieweglowska, Anna et al

in Materialy Budowlane (2006), 12

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See detailInferring Groups of Correlated Failures
Lepropre, Jean; Leduc, Guy ULg

Poster (2006, December)

We compare and evaluate different methods to infer groups of correlated failures. These methods try to group failure events occurring nearly simultaneously in clusters. Indeed if several failures occur ... [more ▼]

We compare and evaluate different methods to infer groups of correlated failures. These methods try to group failure events occurring nearly simultaneously in clusters. Indeed if several failures occur nearly at the same moment in a network, it is possible that these failures have the same root cause. The input data of our algorithms are IP failure notifications that can be provided by several sources. We consider two sources: IS-IS Link State Packets (LSPs) and Syslog messages. Our first results on the Abilene and GÉANT networks show that the inference methods behave differently and that using IS-IS LSPs provides more accurate results than using Syslog messages. [less ▲]

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See detailA numerical comparison of control strategies applied to an existing ice storage system
Lemort, Vincent ULg

in Energy Conversion and Management (2006), 47(20), 3619-3631

While ice storage systems are designed according to a defined strategy for warm day loads, it is interesting to consider other conventional control strategies for mid-season day loads. Three different ... [more ▼]

While ice storage systems are designed according to a defined strategy for warm day loads, it is interesting to consider other conventional control strategies for mid-season day loads. Three different charging-discharging control strategies are applied to an existing cooling plant and compared in terms of operating costs and energy consumption. A cooling plant model is built. A time stage equal to 15 min is considered to simulate numerically a whole charging-discharging process and compare the different control strategies. These simulations take into account existing technical constraints and set points. EES software is used. The operating costs of the cooling plant are evaluated by taking into account both the energy and the demand cost rate. It is shown that an ice storage system can allow savings of operating costs. However, they can increase energy consumption. (c) 2006 Elsevier Ltd. All rights reserved. [less ▲]

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See detailLectotypification of the Famennian pre-ovule Condrusia rumex Stockmans, 1948
Prestianni, Cyrille ULg; Gerrienne, Philippe ULg

in Review of Palaeobotany and Palynology (2006), 142(3-4), 161-164

Condrusia rumex Stockmans 1948 occurs in several localities of the Belgian Evieux Formation (late Famennian, Upper Devonian). It consists of a hastate organ borne at the tip of "slender, dichotomizing ... [more ▼]

Condrusia rumex Stockmans 1948 occurs in several localities of the Belgian Evieux Formation (late Famennian, Upper Devonian). It consists of a hastate organ borne at the tip of "slender, dichotomizing" axes. Various interpretations have been given to this intriguing structure, ranging from a spore-bearing organ to a fern prothallus but recent investigations consider Condrusia to be an ovulate structures produced by early seed plants. The genus Condrusia includes 3 species: C rumex Stockmans, C. minor Stockmans and C. brevis Petrosjan. C rumex was described by Stockmans in 1948, who provided a diagnosis and illustrations, but failed to designate a holotype. We are currently reinvestigating the genus and we here designate and illustrate a lectotype for the genus and species C. rumex. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailAngiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium
Berndt, Sarah ULg; PERRIER d'HAUTERIVE, Sophie ULg; Blacher, Silvia ULg et al

in FASEB Journal (2006), 20(14), 2630-2632

Successful embryo development requires an extensive endometrial angiogenesis in proximity of implantation site. The glycoprotein hCG is produced even before implantation by trophoblast in normal pregnancy ... [more ▼]

Successful embryo development requires an extensive endometrial angiogenesis in proximity of implantation site. The glycoprotein hCG is produced even before implantation by trophoblast in normal pregnancy. In this manuscript, we demonstrate an angiogenic effect of hCG in several in vivo (chick chorioallantoic membrane, matrigel plug assay, aortic ring assay) and in vitro experimental models. In contrast, human placental lactogen (hPL) did not display angiogenic properties. LH/hCG receptor was detected in endothelial cells by reverse-transcriptase polymerase chain reaction (RT-PCR) and by Western blotting. In mice aortic ring assay, angiostimulation by hCG was abrogated by deletion of LH/hCG receptor (LuRKO mice). Use of recombinant hCG and anti-hCG antibody (Ab) further confirmed the specificity of this angiogenic activity. By using dibutyryl cAMP, adenylate cyclase, or protein kinase A inhibitors, we demonstrate that hCG-mediated angiogenesis involves adenylyl-cyclase-protein kinase A activation. Addition of hCG to endometrial epithelial epithelial cells, but not to cultured endothelial cells, stimulated vascular endothelial growth factor (VEGF). VEGF and hCG also displayed additive activities. Altogether, these data demonstrate that peritrophoblastic angiostimulation may result from a paracrine dialogue between trophoblast, epithelial, and endothelial cells through hCG and VEGF. [less ▲]

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See detailQuestions de didactique du français langue seconde (cycle de conf.)
Defays, Jean-Marc ULg

Scientific conference (2006, December)

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See detailAutobiographical memory in non-amnesic alcohol-dependent patients
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; Verbanck, Paul et al

in Psychological Medicine (2006), 36(12), 1707-1715

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic ... [more ▼]

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic patients. The purpose of this study was to investigate (a) non-amnesic alcoholics' ability to recall specific autobiographical memories and (b) their subjective experience when they access specific memories.Method. Twenty non-amnesic (without Korsakoff syndrome) recently detoxified alcoholics and 20 healthy controls completed the Autobiographical Memory Test (AMT), which assesses the frequency of specific (versus general) memories recalled in response to cue words, and the Memory Characteristics Questionnaire (MCQ), which assesses subjective experience (e.g. the amount of sensory and contextual details experienced) when remembering specific events.Results. Alcoholic patients recalled specific memories less frequently and general memories more frequently than healthy controls. Nevertheless, when a specific past event was accessed, alcoholic patients subjectively experienced as many sensory and contextual details as controls.Conclusions. These findings suggest that non-amnesic alcoholics have difficulties strategically accessing event-specific autobiographical knowledge, which might result from changes in frontal lobe function that are associated with alcoholism. [less ▲]

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See detailEvaluation of a Fine-mapping Method Exploiting Linkage Disequilibrium in Livestock Populations: Simulation Study
Kim, J. J.; Farnir, Frédéric ULg

in Asian-Australian Journal of Animal Science (2006), 19(12), 1702

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See detailRapport 2 projet FIRST DEI IMOBIOSE
Goffin, Dorothée ULg

Report (2006)

Le projet FIRST DEI IMOBIOSE est financé par la région wallonne et en partenariat avec la société Meurens Natural. Ce projet a pour but de produire des sirops d’isomaltooligosaccharides prébiotiques à ... [more ▼]

Le projet FIRST DEI IMOBIOSE est financé par la région wallonne et en partenariat avec la société Meurens Natural. Ce projet a pour but de produire des sirops d’isomaltooligosaccharides prébiotiques à partir de sirops de céréales et ce dans le respect du cahier des charges biologique, mais également de les caractériser d’un point de vue de leur composition et de leurs effets sur la santé. [less ▲]

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