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See detailLe cas clinique du mois. Syndrome malin des neuroleptiques et paralysie generale
Foatelli, F. M.; gernay, p; Lievens, Isabelle ULg et al

in Revue Médicale de Liège (2006), 61(12), 807-11

Described in 1960 by Jean Delay in relation to the use of haloperidol, neuroleptic malignant syndrome remains relatively rare, and poorly known by the medical profession. The emergence of the atypical ... [more ▼]

Described in 1960 by Jean Delay in relation to the use of haloperidol, neuroleptic malignant syndrome remains relatively rare, and poorly known by the medical profession. The emergence of the atypical antipsychotic agents and preventive measures which have become general in recent years in hospital departments using dopamine receptor antagonists has not altered the prognosis, which remains potentially fatal in approximately a quarter of cases. This article proposes a descriptive summary of this syndrome in terms of clinical and biological diagnostics as well as of evolution, epidemiology, differential diagnosis and treatment. It describes the case of a patient affected by general paralysis having developed a neuroleptic malignant syndrome, thus the hypothesis what the neuroleptic malignant syndrome preferentially arises in subjects having underlying organic or metabolic problems and provides food for thought regarding the main medical and psychiatric overlaps, the use of dopaminergic agents and the behaviour to be adopted when dealing with a patient presenting with inaugural psychiatric symptomatology. [less ▲]

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See detailCost estimates of brain disorders in Belgium
Schoenen, Jean ULg; Gianni, F.; Schretlen, L. et al

in Acta Neurologica Belgica (2006), 106(4), 208-214

This article presents the data on cost of the major brain disorders in Belgium which were retrieved from "Cost of Disorders of the Brain in Europe" study sponsored by the European Brain Council and ... [more ▼]

This article presents the data on cost of the major brain disorders in Belgium which were retrieved from "Cost of Disorders of the Brain in Europe" study sponsored by the European Brain Council and performed by Stockholm Health Economics. The disorders selected were : addiction, depression, anxiety disorders, brain tumours, dementia, epilepsy, migraine and other headaches, multiple sclerosis, Parkinson's disease, psychotic disorders, stroke and trauma. Figures for prevalence of disorders and direct medical, direct non-medical and indirect costs are based on data coming from available electronic data bases, or when missing for Belgium, best possible estimates or extrapolated data were used. All economic data were transformed to E's for 2004 and adjusted for purchasing power parity (PPP). The results show that the total number of people with any brain disorder in Belgium amounts to 2,9 million in 2004, the most prevalent being anxiety disorders 1.1 million, migraine 860 000, addiction (any) 800.000 and depression 500.000 cases. The total cost of all included brain disorders in Belgium was estimated at 10.6 billion Euros. Most costly per case are brain tumours, multiple sclerosis, stroke and dementia. Because of their higher prevalence, however, depression, dementia, addiction, anxiety disorders and migraine have the highest total costs. Taken together, brain disorders consume 4% of the gross national product and cost each citizen of Belgium E 1029 per year The drug costs for brain disorders constitute only 10% of the total drug market in Belgium, and only 4% of the total cost of brain disorders in Belgium. This should be compared to the cost estimates and to a previous study which showed that brain disorders are responsible for 35% of the total burden of all disorders in Europe. This study suggests therefore that the direct healthcare resources, including expenses for drug therapies, allocated to brain disorders in Belgium are not leveled to the indirect costs and burden of these disorders. A comparison with data available from a direct prospective study in demented Belgian patients suggests that the mathematical estimates presented here reflect quite accurately the real average cost for dementia, although there are large variations depending on disease severity. As, in addition, subjects with brain disorders face collateral costs which have not been taken into account and may vary between countries, it seems worthwhile to conduct, in cooperation with patients associations, a complementary survey in the Belgian ecosystem to establish the cost profile of representative patients for the major brain disorders. Such a survey is being organized by a task force of the Belgian Brain Council. [less ▲]

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See detailA contribution to the audit of an air-conditioning system: modeling, simulation and benchmarking
Adam, Christophe; Andre, Philippe ULg; Hannay, Cleide et al

(2006, December)

This paper intends to show how benchmarks can help in the audit of a HVAC system and how these benchmarks can be generated. The work presented is part of the European “AUDITAC” project. How can an auditor ... [more ▼]

This paper intends to show how benchmarks can help in the audit of a HVAC system and how these benchmarks can be generated. The work presented is part of the European “AUDITAC” project. How can an auditor declare that a given HVAC is “consuming too much”? He can’t make any judgment, if not having some reference, i.e. some “benchmarks” available. Focus is given here to cooling regime, but even then, heating cannot be forgotten (for example, the remaining heating demand can be satisfied thanks some recovery on the condensers of the chillers). The dramatic question is: what should be the consumption(s) for such a building, in such a climate, with such occupancy, such internal loads and such actual indoor environment? Better than to look for a (very hypothetical) global weather index, similar to heating degree-days, it seems more rational to run a simulation model on a few thousands of hours, corresponding to one (or to several) cooling season(s). Current performances of simulation tools make this approach very expedient. The climate can then be considered as it is, without any simplification. The main simplification is still welcome on the system (building + HVAC) side, in order to get calculation robustness, easy understanding and easy parameter identification. In this perspective, the building has to be subdivided in a very limited number of zones and only a few components of the HVAC system have to be included in the simulation model, with as simple as possible control strategies. [less ▲]

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See detailLectotypification of the Famennian pre-ovule Condrusia rumex Stockmans, 1948
Prestianni, Cyrille ULg; Gerrienne, Philippe ULg

in Review of Palaeobotany and Palynology (2006), 142(3-4), 161-164

Condrusia rumex Stockmans 1948 occurs in several localities of the Belgian Evieux Formation (late Famennian, Upper Devonian). It consists of a hastate organ borne at the tip of "slender, dichotomizing ... [more ▼]

Condrusia rumex Stockmans 1948 occurs in several localities of the Belgian Evieux Formation (late Famennian, Upper Devonian). It consists of a hastate organ borne at the tip of "slender, dichotomizing" axes. Various interpretations have been given to this intriguing structure, ranging from a spore-bearing organ to a fern prothallus but recent investigations consider Condrusia to be an ovulate structures produced by early seed plants. The genus Condrusia includes 3 species: C rumex Stockmans, C. minor Stockmans and C. brevis Petrosjan. C rumex was described by Stockmans in 1948, who provided a diagnosis and illustrations, but failed to designate a holotype. We are currently reinvestigating the genus and we here designate and illustrate a lectotype for the genus and species C. rumex. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailFrom model validation to production of reference simulations: how to increase reliability and applicability of building and HVAC simulation models
Adam, Christophe; Andre, Philippe ULg; Georges, Bernard ULg et al

(2006, December)

Validation of simulation models appears from a long time as a key issue in order to promote a more intensive and more efficient use of simulation models in the field of building and HVAC simulation. IEA ... [more ▼]

Validation of simulation models appears from a long time as a key issue in order to promote a more intensive and more efficient use of simulation models in the field of building and HVAC simulation. IEA Annex 34/43 originally targeted a number of specific applications where a more advanced validation was required: ground coupling problems, multizone building, shading, day lighting and cooling load interaction, HVAC components and ventilated facades. These validation exercises were built on the large methodological experience obtained in previous projects and address sometimes very fundamental problems of heat transfer in buildings. Consulting engineers and practitioners might see these exercises as a bit too far from their objectives and it is the reason why an additional activity was proposed with the specific aim of producing, based upon the results of the validation of models, a set of reference simulations. These applications cover a range of building types (residential, commercial) and systems (production, distribution emission) and run in a variety of climates. The paper will describe how models dedicated to these applications were developed, starting from validation results, going through the selection and consolidation of simulation hypothesises and ending with a number that might be considered as reference for the concerned applications. The paper will concentrate on models required by a residential building application (multizone building equipped with a heat pump or a condensing boiler). Simulations make use of both EES and TRNSYS software and both software are applied in parallel as far as possible in the different applications in order to get a better judgment of their potential advantages and drawbacks. The use of reference simulations in view of qualifying normative methods currently in development in the frame of the European Energy Performance in Buildings Directive is also addressed and demonstrated in the paper. [less ▲]

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See detailDes élections provinciales sans grand changement ?
Hermans, Michel ULg

Article for general public (2006)

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See detailModeling and simulation of an air conditioning chilled water system
Lebrun, Jean ULg; Lemort, Vincent ULg; Teodorese, Ion

(2006, December)

This paper is giving an overview of problems encountered and solutions available for the simulation of an air conditioning system. Focus is given on the chilling water subsystem (from the chiller to the ... [more ▼]

This paper is giving an overview of problems encountered and solutions available for the simulation of an air conditioning system. Focus is given on the chilling water subsystem (from the chiller to the cooling coil). Main component simulation models (chillers, pumps, piping, valves, cooling coils and fans) are presented; they are tuned on manufacturer’s catalogue data. The way of integrating these models into a global HVAC system simulation is illustrated thanks to one example: the simulation of (a part of) a real chilled water loop, which is submitted to an exhaustive monitoring. Cooling demands and corresponding energy consumptions are systematically simulated and measured on one-minute time basis. This provides the opportunity for a global checking of the simulation by comparing simulated and measured cooling coil outputs. Further work should also include comparisons on chiller consumptions. [less ▲]

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See detail"Er war ein Verlorener". Géza von Cziffra erinnert sich an Joseph Roth
Küpper, Achim ULg

in Literaturkritik.de (2006)

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See detailHigh prevalence of pituitary adenomas: A cross-sectional study in the province of Liege, Belgium
Daly, Adrian ULg; Rixhon, M.; Adam, Christelle et al

in Journal of Clinical Endocrinology and Metabolism (2006), 91(12), 4769-4775

Context: Prevalence data are important for assessing the burden of disease on the health care system; data on pituitary adenoma prevalence are very scarce. Objective: The objective of the study was to ... [more ▼]

Context: Prevalence data are important for assessing the burden of disease on the health care system; data on pituitary adenoma prevalence are very scarce. Objective: The objective of the study was to measure the prevalence of clinically relevant pituitary adenomas in a well-defined population. Design: This was a cross-sectional, intensive, case-finding study performed in three regions of the province of Liège, Belgium, to measure pituitary adenoma prevalence as of September 30, 2005. Setting: The study was conducted in specialist and general medical practitioner patient populations, referral hospitals, and investigational centers. Methods: Three demographically and geographically distinct districts of the province of Liège were delineated precisely using postal codes. Medical practitioners in these districts were recruited, and patients with pituitary adenomas under their care were identified. Diagnoses were confirmed after retrieval of clinical, hormonal, radiological, and pathological data; full demographic and therapeutic follow-up data were collected in all cases. Results: Sixty-eight patients with clinically relevant pituitary adenomas were identified in a population of 71,972 individuals; the mean (± SD) prevalence was 94 ± 19.3 cases per 100,000 population (95% confidence interval, 72.2 to 115.8). The group was 67.6% female and had a mean age at diagnosis of 40.3 yr; 42.6% had macroadenomas and 55.9% underwent surgery. Prolactinomas comprised 66% of the group, with the rest having nonsecreting tumors (14.7%), somatotropinomas (13.2%), or Cushing’s disease (5.9%); 20.6% had hypopituitarism. Conclusion: The prevalence of pituitary adenomas in the study population (one case in 1064 individuals) was more than 3.5–5 times that previously reported. This increased prevalence may have important implications when prioritizing funding for research and treatment of pituitary adenomas. [less ▲]

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See detailLe sens de l’orientation. Résistance, ouverture et relégation
Andre, Géraldine ULg

Conference (2006, December)

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See detailA numerical comparison of control strategies applied to an existing ice storage system
Lemort, Vincent ULg

in Energy Conversion and Management (2006), 47(20), 3619-3631

While ice storage systems are designed according to a defined strategy for warm day loads, it is interesting to consider other conventional control strategies for mid-season day loads. Three different ... [more ▼]

While ice storage systems are designed according to a defined strategy for warm day loads, it is interesting to consider other conventional control strategies for mid-season day loads. Three different charging-discharging control strategies are applied to an existing cooling plant and compared in terms of operating costs and energy consumption. A cooling plant model is built. A time stage equal to 15 min is considered to simulate numerically a whole charging-discharging process and compare the different control strategies. These simulations take into account existing technical constraints and set points. EES software is used. The operating costs of the cooling plant are evaluated by taking into account both the energy and the demand cost rate. It is shown that an ice storage system can allow savings of operating costs. However, they can increase energy consumption. (c) 2006 Elsevier Ltd. All rights reserved. [less ▲]

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See detailImpact of 2D and 3D vision on performance of novice subjects using da Vinci robotic system
Blavier, Adelaïde ULg; Gaudissart, Quentin; Cadière, Guy-Bernard et al

in Acta Chirurgica Belgica (2006), 106(6), 662-664

Purpose of the study : The aim of this study was to evaluate the impact of 3D and 2D vision on performance of novice subjects using da Vinci robotic system. Methods : 224 nurses without any surgical ... [more ▼]

Purpose of the study : The aim of this study was to evaluate the impact of 3D and 2D vision on performance of novice subjects using da Vinci robotic system. Methods : 224 nurses without any surgical experience were divided into two groups and executed a motor task with the robotic system in 2D for one group and with the robotic system in 3D for the other group. Time to perform the task was recorded. Results : Our data showed significant better time performance in 3D view (24.67 +/- 11.2) than in 2D view (40.26 +/- 17.49, P < 0.001). Conclusions : Our findings emphasized the advantage of 3D vision over 2D view in performing surgical task, encouraging the development of efficient and less expensive 3D systems in order to improve the accuracy of surgical gesture, the resident training and the operating time. [less ▲]

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See detailEntre méfiance et intégration. Les germanophones dans l'armée belge (1920-1955)
Brüll, Christoph ULg

in Cahiers Belges d'Histoire Militaire (2006), 4

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See detailAn exceptional specimen of the early land plant Cooksonia paranensis, and a hypothesis on the life cycle of the earliest eutracheophytes
Gerrienne, Philippe ULg; Dilcher, D. L.; Bergamaschi, S. et al

in Review of Palaeobotany and Palynology (2006), 142(3-4), 123-130

An exceptionally large specimen of the early land plant Cooksonia paranensis Gerrienne et al. has been discovered from the type locality (Jackson de Figueiredo, Parana Basin, Brazil; early Lochkovian ... [more ▼]

An exceptionally large specimen of the early land plant Cooksonia paranensis Gerrienne et al. has been discovered from the type locality (Jackson de Figueiredo, Parana Basin, Brazil; early Lochkovian, Early Devonian). This nearly complete specimen consists of five dichotomous axes attached at their base to a small thalloid(?) structure. Each terminal axis segment ends in an expanded, cup-like, empty tip. Three interpretations of the specimen are proposed. (1) The whole specimen is a gametophyte of the Sciadopkyton-type, with a central area from which five axes depart; under this interpretation, the terminal cups are gametangiophores. (2) The basal structure represents the remains of a rhizome bearing five upright aerial axes, in which case the whole plant is a sporophyte. (3; our favoured hypothesis) The specimen is a cluster of five individual sporophytes still attached to the remains of a small female or bisexual gametophyte. In the latter case, this fossil is evidence that reduced thalloid gametophytes and branched axial sporophytes are plesiomorphic among the earliest eutracheophytes. We suggest that a major difference in life cycle defines a basal dichotomy in tracheophytes. Eutracheophyta, including all living vascular plants, have a heteromorphic, sporophyte dominant alternation of generations, whereas their extinct sister-group Rhymopsida (renamed here Paratracheophyta) is characterised by a more or less isomorphic alternations of generations. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailMicro-macro mechanical modeling of bone-implant interface by means of the homogenization theory
Amor, Nadia; Van Cleynenbreugel, Tim; Geris, Liesbet ULg et al

Poster (2006, December)

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See detailInżyneria powierzchni betonu. Część 2. Wpływ obrobki na powstawanie rys
Courard, Luc ULg; Garbacz, Andrzej; Nieweglowska, Anna et al

in Materialy Budowlane (2006), 12

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See detailMorphological and molecular characterization of planktonic cyanobacteria from Belgium and Luxembourg
Willame, R.; Boutte, C.; Grubisic, Stana ULg et al

in Journal of Phycology (2006), 42(6), 1312-1332

For the first time in Belgium and Luxembourg, the diversity and taxonomy of 95 cyanobacterial strains isolated from freshwater blooms were assessed by the comparison of phenotypes and partial 16S rRNA ... [more ▼]

For the first time in Belgium and Luxembourg, the diversity and taxonomy of 95 cyanobacterial strains isolated from freshwater blooms were assessed by the comparison of phenotypes and partial 16S rRNA gene sequences. The results showed the high diversity of nanoplanktonic, picoplanktonic, and benthic-periphytic cyanobacteria accompanying the main bloom-forming taxa. Indeed, besides 15 morphotypes of bloom-forming taxa, seven non-bloom-forming planktonic morphotypes and 11 morphotypes from benthic-periphytic taxa were isolated in culture from the plankton samples of 35 water bodies. The bloom-forming strains belonged to the genera Microcystis, Woronichinia, Planktothrix, Anabaena, and Aphanizomenon, whereas the other strains isolated from the same samples were assigned to the nanoplanktonic Aphanocapsa, Aphanothece, Snowella, and Pseudanabaena; to the picoplanktonic Cyanobium; and to the benthic periphytic Geitlerinema, Komvophoron, Leptolyngbya, Lyngbya, Phormidium, Calothrix, Nostoc, and Trichormus. The results supported both the polyphyletism of genera such as Aphanocapsa, Aphanothece, Leptolyngbya, Geitlerinema, Anabaena, and Aphanizomenon as well as the validity of genera such as Microcystis, Planktothrix, and Pseudanabaena with gas vesicles and cells constricted at the cross wall. The results obtained showed the close relationship between Snowella and Woronichinia for which very few sequences exist. The first sequence of Komvophoron appeared poorly related to other available cyanobacterial sequences. Although in a few cases a good agreement existed between phenotypic and genotypic features, there was generally a discrepancy. Strains with identical morphotypes show small differences in the 16S rRNA sequences, which might be related to the different chemical properties of their habitats. The results showed the importance of the polyphasic approach in order to improve the taxonomy of cyanobacteria. [less ▲]

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See detailAutobiographical memory in non-amnesic alcohol-dependent patients
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; Verbanck, Paul et al

in Psychological Medicine (2006), 36(12), 1707-1715

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic ... [more ▼]

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic patients. The purpose of this study was to investigate (a) non-amnesic alcoholics' ability to recall specific autobiographical memories and (b) their subjective experience when they access specific memories.Method. Twenty non-amnesic (without Korsakoff syndrome) recently detoxified alcoholics and 20 healthy controls completed the Autobiographical Memory Test (AMT), which assesses the frequency of specific (versus general) memories recalled in response to cue words, and the Memory Characteristics Questionnaire (MCQ), which assesses subjective experience (e.g. the amount of sensory and contextual details experienced) when remembering specific events.Results. Alcoholic patients recalled specific memories less frequently and general memories more frequently than healthy controls. Nevertheless, when a specific past event was accessed, alcoholic patients subjectively experienced as many sensory and contextual details as controls.Conclusions. These findings suggest that non-amnesic alcoholics have difficulties strategically accessing event-specific autobiographical knowledge, which might result from changes in frontal lobe function that are associated with alcoholism. [less ▲]

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See detailPreface: A tribute to Muriel Fairon-Demaret
Gerrienne, Philippe ULg

in Review of Palaeobotany and Palynology (2006), 142(3-4), 61-61

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