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See detailQuestions de didactique du français langue seconde (cycle de conf.)
Defays, Jean-Marc ULg

Scientific conference (2006, December)

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See detailOn the understanding of the physical changes in inulin powder as a function of water activity.
Ronkart, Sébastien; Paquot, Michel ULg; Goffin, Dorothée ULg et al

Poster (2006, December)

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See detailAn exceptional specimen of the early land plant Cooksonia paranensis, and a hypothesis on the life cycle of the earliest eutracheophytes
Gerrienne, Philippe ULg; Dilcher, D. L.; Bergamaschi, S. et al

in Review of Palaeobotany and Palynology (2006), 142(3-4), 123-130

An exceptionally large specimen of the early land plant Cooksonia paranensis Gerrienne et al. has been discovered from the type locality (Jackson de Figueiredo, Parana Basin, Brazil; early Lochkovian ... [more ▼]

An exceptionally large specimen of the early land plant Cooksonia paranensis Gerrienne et al. has been discovered from the type locality (Jackson de Figueiredo, Parana Basin, Brazil; early Lochkovian, Early Devonian). This nearly complete specimen consists of five dichotomous axes attached at their base to a small thalloid(?) structure. Each terminal axis segment ends in an expanded, cup-like, empty tip. Three interpretations of the specimen are proposed. (1) The whole specimen is a gametophyte of the Sciadopkyton-type, with a central area from which five axes depart; under this interpretation, the terminal cups are gametangiophores. (2) The basal structure represents the remains of a rhizome bearing five upright aerial axes, in which case the whole plant is a sporophyte. (3; our favoured hypothesis) The specimen is a cluster of five individual sporophytes still attached to the remains of a small female or bisexual gametophyte. In the latter case, this fossil is evidence that reduced thalloid gametophytes and branched axial sporophytes are plesiomorphic among the earliest eutracheophytes. We suggest that a major difference in life cycle defines a basal dichotomy in tracheophytes. Eutracheophyta, including all living vascular plants, have a heteromorphic, sporophyte dominant alternation of generations, whereas their extinct sister-group Rhymopsida (renamed here Paratracheophyta) is characterised by a more or less isomorphic alternations of generations. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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See detailThe in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells
Servotte, S.; Camby, I.; Debeir, O. et al

in Neuropathology & Applied Neurobiology (2006), 32(6), 575-584

Astrocytic tumours are associated with dismal prognoses due to their pronounced ability to diffusely invade the brain parenchyma. Various neuropeptides, including gastrin, are able to modulate tumour ... [more ▼]

Astrocytic tumours are associated with dismal prognoses due to their pronounced ability to diffusely invade the brain parenchyma. Various neuropeptides, including gastrin, are able to modulate tumour astrocyte migration. While neurotensin has been shown to influence the proliferation of glioma cells and the migratory ability of a large set of other cell types, its role in glioma cell migration has never been investigated. Neurotensin-induced modifications to the motility features of human U373 glioblastoma cells therefore constitute the topic of the present study. We evidenced that three subtypes of neurotensin receptors (NTR1, NTR2 and NTR3) are expressed in U373 glioblastoma cells, at least as far as their mRNAs are concerned. Treating U373 tumour cells with 10 nM neurotensin markedly modified the morphological patterns of these cells and also profoundly altered the organization of their actin cytoskeletons. Pull-down assays revealed that neurotensin induced the activation in U373 cells of both Rac1 and Cdc42 but not RhoA. Scratch wound assays evidenced that neurotensin (0.1 and 10 nM) very significantly inhibited wound colonization by U373 cells cultured in the absence of serum. In addition, quantitative phase-contrast videomicroscopy analyses showed that neurotensin decreases the motility levels of U373 glioblastoma cells when these cells are cultured on plastic. In sharp contrast, neurotensin stimulates the motility of U373 cells when they are cultured on laminin, which is a pro-adhesive extracellular matrix component ubiquitously secreted by glioma cells. Our data thus strongly suggest that, in addition to gastrin, neurotensin is a neuropeptide capable of modulating tumour astrocyte migration into the brain parenchyma. [less ▲]

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See detailPromotion de la santé à l'école ... Les modifications tant attendues de deux décrets
Vandoorne, Chantal ULg

in Education Santé (2006), (218), 7-8

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See detailSound field modeling in architectural acoustics using a diffusion equation
Picaut, Judicaël; Valeau, Vincent; Billon, Alexis ULg et al

Conference (2006, December)

A numerical approach is proposed to model the reverberated sound field in rooms. The model is based on the numerical implementation of a diffusion model enabling spatial variations of the sound energy ... [more ▼]

A numerical approach is proposed to model the reverberated sound field in rooms. The model is based on the numerical implementation of a diffusion model enabling spatial variations of the sound energy within a room, unlike the statistical theory. The proposed method allows to take into account most of complex phenomena encountered in room acoustics, like mixed reflections on walls (diffuse and specular), low and high absorption on walls, atmospheric attenuation, fitted zones. Moreover, the model can be applied to complex geometries, like multiple coupled rooms of different sizes. In this paper, the model and its numerical implementation are first detailed. Then, an application is proposed for a complex geometry defined by multiple coupled rooms with fitting objects, including low and high absorption on walls, in terms of sound level and reverberation times. The main interest of the model is that such approach requires less computational time in comparison with common approaches like ray-tracing simulations. [less ▲]

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See detailTranscriptional regulation of the mouse doublecortin gene in differentiating neurons
Plumier, Jean-Christophe ULg; Muller, Marc ULg; Rogister, Bernard ULg et al

in International Journal of Developmental Neuroscience (2006, December), 24(8), 535

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See detailSynthesis of block copolymers and their use for biomedical applications
Jérôme, Christine ULg

Conference (2006, December)

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See detailPreface: A tribute to Muriel Fairon-Demaret
Gerrienne, Philippe ULg

in Review of Palaeobotany and Palynology (2006), 142(3-4), 61-61

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See detailBuilding EnCOrE : Encyclopédie de Chimie Organique Electronique
Colaux, Catherine ULg; Seleck, Caroline; Henry, Julie et al

Poster (2006, December)

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See detailResults towards identifiability properties of biochemical reaction networks
Farina, Marcello; Findeisen, Rolf; Bullinger, Eric ULg et al

in Proc. of the 45th IEEE Conference on Decision and Control, San Diego, USA (2006, December)

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions ... [more ▼]

In this paper we consider the question of parameter identifiability for biochemical reaction networks, as typically encountered in systems biology. Specifically, we are interested in deriving conditions on the biochemical reaction network and on the measured outputs that guarantee identifiability of the parameters. Taking the specific system structure of biochemical reaction networks into account, we derive sufficient conditions for local parameter identifiability based on a suitable system expansion which does not any more directly depend on the parameters. Rather, as shown, the problem of identifiability can be recast as the question of observability of the (parameter free) expanded system. The conditions derived are exemplified considering a simple example [less ▲]

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See detailLe portrait dans Daguerréotypes d'Agnès Varda
Van Cauwenberge, Geneviève ULg

Conference (2006, December)

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See detail"Er war ein Verlorener". Géza von Cziffra erinnert sich an Joseph Roth
Küpper, Achim ULg

in Literaturkritik.de (2006)

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See detailGeneralized Shape And Topology Optimization: Recent Developments And Application Perspectives To Automotive Structures
Duysinx, Pierre ULg; Van Miegroet, Laurent ULg; Remouchamps, Alain et al

in New Advances in Body Engineering - Lightweight design, passive safety, pedestrian protection, and numerical optimization (2006, December)

More than 15 years after the seminal work by Bendsøe and Kikuchi, topology optimization of structures has taken advantage of my research efforts and has now become a commercial available tool (e.g ... [more ▼]

More than 15 years after the seminal work by Bendsøe and Kikuchi, topology optimization of structures has taken advantage of my research efforts and has now become a commercial available tool (e.g. OptiStruct by Altair, Topol by Samtech, etc.). These software tools are daily used in automotive industry and provide engineers with a rational tool for preliminary design of efficient structural components. This paper presents the status of available topology optimization tools and introduces the recent developments that extend their capabilities in order to handle stress constraints, manufacturing constraints, etc. The communication also presents a novel approach of generalized shape optimization that has been introduced to circumvent the difficulties of parametric shape optimization and to complement topology optimization. The approach is based on the eXtended Finite Element Method (XFEM) and the Level Set Description of the geometry. The Level Set description introduces smooth curve descriptions and allows modifying the connectivity of the wholes. The XFEM works with a fixed mesh as in topology optimization, which makes the method very convenient for engineers. Thus the novel approach is likely to bring the next future evolution of structural optimization. Impressive capabilities of this new generation approach will be demonstrated. Application examples from automotive and aerospace engineering will illustrate the different possibilities offered by two approaches. [less ▲]

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See detailMorphological and molecular characterization of planktonic cyanobacteria from Belgium and Luxembourg
Willame, R.; Boutte, C.; Grubisic, Stana ULg et al

in Journal of Phycology (2006), 42(6), 1312-1332

For the first time in Belgium and Luxembourg, the diversity and taxonomy of 95 cyanobacterial strains isolated from freshwater blooms were assessed by the comparison of phenotypes and partial 16S rRNA ... [more ▼]

For the first time in Belgium and Luxembourg, the diversity and taxonomy of 95 cyanobacterial strains isolated from freshwater blooms were assessed by the comparison of phenotypes and partial 16S rRNA gene sequences. The results showed the high diversity of nanoplanktonic, picoplanktonic, and benthic-periphytic cyanobacteria accompanying the main bloom-forming taxa. Indeed, besides 15 morphotypes of bloom-forming taxa, seven non-bloom-forming planktonic morphotypes and 11 morphotypes from benthic-periphytic taxa were isolated in culture from the plankton samples of 35 water bodies. The bloom-forming strains belonged to the genera Microcystis, Woronichinia, Planktothrix, Anabaena, and Aphanizomenon, whereas the other strains isolated from the same samples were assigned to the nanoplanktonic Aphanocapsa, Aphanothece, Snowella, and Pseudanabaena; to the picoplanktonic Cyanobium; and to the benthic periphytic Geitlerinema, Komvophoron, Leptolyngbya, Lyngbya, Phormidium, Calothrix, Nostoc, and Trichormus. The results supported both the polyphyletism of genera such as Aphanocapsa, Aphanothece, Leptolyngbya, Geitlerinema, Anabaena, and Aphanizomenon as well as the validity of genera such as Microcystis, Planktothrix, and Pseudanabaena with gas vesicles and cells constricted at the cross wall. The results obtained showed the close relationship between Snowella and Woronichinia for which very few sequences exist. The first sequence of Komvophoron appeared poorly related to other available cyanobacterial sequences. Although in a few cases a good agreement existed between phenotypic and genotypic features, there was generally a discrepancy. Strains with identical morphotypes show small differences in the 16S rRNA sequences, which might be related to the different chemical properties of their habitats. The results showed the importance of the polyphasic approach in order to improve the taxonomy of cyanobacteria. [less ▲]

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See detailTreating gliomas with glucocorticoids: from bedside to bench
Piette, Caroline ULg; Munaut, Carine ULg; Foidart, Jean-Michel ULg et al

in Acta Neuropathologica (2006), 112(6), 651-664

Glucocorticoids are used in the treatment of gliomas to decrease tumour-associated oedema and to reduce the risk of acute encephalopathy associated with radiotherapy. However, the mechanisms by which ... [more ▼]

Glucocorticoids are used in the treatment of gliomas to decrease tumour-associated oedema and to reduce the risk of acute encephalopathy associated with radiotherapy. However, the mechanisms by which glucocorticoids work are still largely unknown. In this paper, we survey the experimental and clinical evidence for the effects of glucocorticoids on tumour cell proliferation, apoptosis and sensitivity to chemotherapy, angiogenesis and vascular permeability. We then review current guidelines on the choice of molecule, dose and duration of glucocorticoid treatment for gliomas. [less ▲]

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