References of "2005"
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See detailSystem Analysis of a Programmed Cell Death Model
Bullinger, Eric ULg

in IEEE Conference on Decision and Control (2005, December)

Apoptosis is a programmed cell death by which the organism removes unwanted cells. Its core reactions can be described by a system of differential equations exhibiting multiple steady-states. In this ... [more ▼]

Apoptosis is a programmed cell death by which the organism removes unwanted cells. Its core reactions can be described by a system of differential equations exhibiting multiple steady-states. In this paper we analyse how this model can include both very slow dynamics for the lag phase before apoptosis (in theory up to several days) while the apoptosis itself is more switch-like with changes occurring within minutes. We both describe how the trajectories evolve during the lag phase and show which of the states have the most impact on the slow dynamics. [less ▲]

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See detailFactors affecting black grouse numbers : an overview of the part of predators. European conference, black grouse endangered species,
Loneux, Michèle ULg; Kolb, Karl-Heinz; Ruwet, Jean-Claude et al

in PLUMMER, Ron (Ed.) European Conference 'Cynhadledd Ceiliog Y Rhos' Black Grouse Endangered Species (2005, December)

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See detailTriggering mechanisms of limit cycle oscillations due to aeroelastic instability
Lee, Y. S.; Vakakis, Alexander F.; Bergman, Lawrence A. et al

in Journal of Fluids & Structures (2005), 21

We show that a cascade of resonance captures constitutes the triggering mechanism of limit cycle oscillations (LCOs) due to aeroelastic instability of rigid wings in flow. We consider a two-degree-of ... [more ▼]

We show that a cascade of resonance captures constitutes the triggering mechanism of limit cycle oscillations (LCOs) due to aeroelastic instability of rigid wings in flow. We consider a two-degree-of-freedom (2-dof) wing model in subsonic flow with cubic nonlinear stiffnesses at the support. Under the assumption of quasi-steady aerodynamics, we apply a complexification/averaging technique to express the dynamics of fluid-structure interactions in terms of three fast-frequency components; these are the two linear natural frequencies corresponding to heave and pitch, and a superharmonic at three times the pitch frequency. Bifurcation analysis of the resulting set of modulation equations governing the slow dynamics is carried out via the method of numerical continuation, and reveals the different types of steady state motions realized as parameters vary. It turns out that the LCO triggering mechanism consists of a combination of different dynamic phenomena, taking place at three main stages or regimes: attraction to transient resonance captures (TRCs), escapes from these captures and, finally, entrapments into permanent resonance captures (PRCs). We examine numerically and analytically the dynamics at each of these stages by means of wavelet transform analysis, study of the evolution of appropriately defined phase variables in projections of the phase space of the dynamics, and analysis of instantaneous energy exchanges between the various nonlinear modes involved. The general conclusion is that an initial excitation of the heave mode by the flow acts as the triggering mechanism for the excitation of the pitch mode through nonlinear interactions resulting from the resonance captures and escapes. The eventual excitation of the pitch mode signifies the appearance of an LCO of the in-flow wing. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

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See detailThree year joint space narrowing predicts long term incidence of knee surgery in patients with osteoarthritis: an eight year prospective follow up study
Bruyère, Olivier ULg; Richy, F.; Reginster, Jean-Yves ULg

in Annals of the Rheumatic Diseases (2005), 64(12), 1727-1730

OBJECTIVE: To assess the clinical relevance of mean and minimum femorotibial joint space narrowing (JSN) for predicting future osteoarthritis related surgery in patients with knee osteoarthritis. METHODS ... [more ▼]

OBJECTIVE: To assess the clinical relevance of mean and minimum femorotibial joint space narrowing (JSN) for predicting future osteoarthritis related surgery in patients with knee osteoarthritis. METHODS: 126 subjects with primary knee osteoarthritis were followed prospectively for a mean eight years. Minimum and mean joint space width (JSW) were assessed from standard x rays at baseline and after a follow up of three years. The rate of knee osteoarthritis related surgery was recorded for the following five years. RESULTS: After a mean follow up of eight years, 16 patients (12.7%) had received osteoarthritis related joint surgery. The areas under the curves (AUC) resulting from the receiver operating characteristic curve analyses for predicting osteoarthritis surgery were 0.73 (p=0.006) for minimum JSN and 0.55 (p=0.54) for mean JSN. The cut off for minimum JSN maximising sensitivity and specificity for predicting future surgery was a change of 0.7 mm or more in minimum joint space width over a period of three years. However, no meaningful differences were observed for cut off values between 0.5 and 0.8 mm The relative risk (adjusted for age, body mass index, baseline symptoms, and baseline JSW) of experiencing osteoarthritis related surgery during the eight year of follow up was 5.15 (95% confidence interval, 1.70 to 15.60) (p=0.004) in patients with a minimum joint space narrowing of 0.7 mm or more during the first three years of the study. CONCLUSIONS: A cut off of 0.5 to 0.8 mm in minimum JSN, measured on standard x rays, reflects a clinically relevant progression in patients with knee osteoarthritis. [less ▲]

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See detailQuantifying consciousness
Laureys, Steven ULg; Piret, Sonia ULg; Ledoux, Didier ULg

in Lancet Neurology (2005), 4(12), 789-790

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See detailDépression et maladies coronariennes: quand les émotions nous brisent le coeur...
Massart, Nicolas ULg; Triffaux, Jean-Marc ULg

in Revue Médicale de Liège (2005), 60(12), 931-8

Depression and cardiovascular diseases represent a major public health problem worldwide. Recent studies have shown that depression is a risk factor for the development of coronary artery disease (CAD) in ... [more ▼]

Depression and cardiovascular diseases represent a major public health problem worldwide. Recent studies have shown that depression is a risk factor for the development of coronary artery disease (CAD) in healthy people and also increases morbidity and mortality in depressed patients with CAD. Others studies have shown that selective serotonin inhibitors (SSRIs) constitute a safe and effective treatment for depressed patients with heart disease. There are also data suggesting that treating depression with SSRIs has a protective role in myocardial infarction and may improve outcomes, including mortality. [less ▲]

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See detailControl of puberty by excitatory amino acid neurotransmitters and its clinical implications
Parent, Anne-Simone ULg; Matagne, V.; Bourguignon, Jean-Pierre ULg

in Endocrine (2005), 28(3), 281-285

Excitatory amino acids, glutamate in particular, have a marked stimulatory effect on the reproductive axis, particulary at puberty. Glutamate, N-methyl-D-aspartate (NMDA), and kainate stimulate ... [more ▼]

Excitatory amino acids, glutamate in particular, have a marked stimulatory effect on the reproductive axis, particulary at puberty. Glutamate, N-methyl-D-aspartate (NMDA), and kainate stimulate gonadotropin-releasing hormone (GnRH) secretion in immature mammals and NMDA receptor stimulation results in precocious puberty in rats and monkeys. Puberty is characterized by an increased sensitivity of GnRH to glutamate as well as an increase in glutaminase activity in the hypothalamus. Glutamatergic and GABAergic regulation of GnRH secretion seem strongly interdependent around puberty. in addition to the transsynaptic glutamatergic regulation of GnRH secretion, a coordinated activity of glutamatergic neurons and astroglial cells has been shown to play an active role in puberty. The participation of kainate receptors in the estradiol-induced advancement of puberty suggest that these receptors may be involved in the estradiol-mediated activation of GnRH secretion at puberty. A case of precocious puberty associated with hyperglycinemia illustrates the NMDA involvement in puberty in humans. in this patient, the occurrence of precocious puberty was thought to result from excessive stimulation by glycine of the NMDA receptors linked to the GnRH neurons. Glutamate plays several roles in the hypothalamic mechanism of puberty as it has been shown in animal models, but there are still few clinical data supporting the role of glutamate in human puberty. [less ▲]

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See detailMise en place d’une stratégie de communication et de contrôle de la qualité écologique et sociale fondée sur l’étiquetage, les indications de qualité et la force de marque pour les vêtements, les articles de sport et les voitures
Fraselle, Nadine; Van Caillie, Didier ULg

Report (2005)

This report describes which are the practices implemented by firms in the furnishment industry, in the auto industry and in the sport industry to signal and to control the external Ecological and Societal ... [more ▼]

This report describes which are the practices implemented by firms in the furnishment industry, in the auto industry and in the sport industry to signal and to control the external Ecological and Societal Quality of their products. [less ▲]

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See detailInfluence of emotion on memory for temporal information
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg

in Emotion (Washington, D.C.) (2005), 5(4), 503-507

Contextual information. such as color and spatial location, has been found to be better remembered for emotional than for neutral items. The current study examined whether the influence of emotion extends ... [more ▼]

Contextual information. such as color and spatial location, has been found to be better remembered for emotional than for neutral items. The current study examined whether the influence of emotion extends to memory for another fundamental feature of episodic memory: temporal information. Results from a list-discrimination paradigm showed that (a) item memory was enhanced for both negative and positive pictures compared with neutral ones and was better for negative than for positive pictures and (b) temporal information was better remembered for negative than for positive and neutral pictures, whereas positive and neutral pictures did not differ from each other. These findings are discussed in relation to the processes involved in memory for temporal information. [less ▲]

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See detailIntegration de la pharmacogenetique dans la pratique medicale
Dideberg, Vinciane ULg; Bours, Vincent ULg

in Revue Médicale de Liège (2005), 60(12), 918-22

Today, the initiation of any medical treatment still raises questions about its efficacy and safety. Indeed, therapeutic responses vary over time and between individuals and are influenced by age, sex ... [more ▼]

Today, the initiation of any medical treatment still raises questions about its efficacy and safety. Indeed, therapeutic responses vary over time and between individuals and are influenced by age, sex, other treatments and the pathology itself. Genetic factors are thought to be responsible for 20 to 95% of these individual variations. Recent advances in biotechnology, molecular genetics and genomics allow a better understanding of drug metabolism and action. Pharmacogenetics, compiling phenotypic and genotypic data, may lead to a more personalized treatment. To allow a better approach of pharmacogenetics and pharmacogenomics, we will define these two terms and describe their actual and future clinical application. [less ▲]

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See detailGérer un projet CRM en PME. Guide méthodologique à destination des responsables internes de projets
Lisein, Olivier ULg

Learning material (2005)

Gérer l’élaboration et l’implémentation d’un projet TIC : tel est le défi auquel sont confrontées de plus en plus d’entreprises. Comme le montrent les expériences en la matière, arriver à des résultats ... [more ▼]

Gérer l’élaboration et l’implémentation d’un projet TIC : tel est le défi auquel sont confrontées de plus en plus d’entreprises. Comme le montrent les expériences en la matière, arriver à des résultats tangibles et engendrer un return positif sur les investissements consentis nécessitent que ces projets soient mûrement réfléchis. Il importe pour ce faire que soit menée une approche transversale de gestion du projet, prenant en compte, outre bien entendu ses aspects technologiques, la façon dont le projet TIC s’insère dans le contexte de l’entreprise (organisation du travail, structure, processus, flux d’information, etc.) et se positionne par rapport et aux objectifs stratégiques poursuivis par l’entreprise (positionnement sur les marchés, avantage concurrentiel, etc.). C’est dans cet objectif qu’est conçu ce guide méthodologique. Axé sur la question de la gestion de l’implémentation d’un projet CRM dans une PME, ce cahier a pour vocation d’aider les gestionnaires de projet de ce type dans leurs démarches de réflexion. Adapté au contexte des PME ainsi qu’aux spécificités et attendus des solutions informatiques de type CRM, ce guide méthodologique offre un canevas aux responsables de projet internes aux entreprises, à qui est confiée la responsabilité de la gestion de l’implémentation d’un CRM. La démarche qui leur est proposée, au travers de ce document, se veut transversale et centrée sur les différentes composantes de la gestion de leur projet : stratégique, organisationnelle, technologique et humaine. En ce sens, ce guide méthodologique entend couper court à toute fausse idée - encore largement répandue - qui ferait croire qu’un projet CRM ne serait qu’un "simple" projet informatique à gérer. Au contraire, la mise en place d’un solution informatique de ce type s’avère être un véritable projet stratégique et organisationnel pour la PME qui décide d’y recourir, demandant de ce fait à être géré en conséquence. Au niveau de sa présentation, ce guide est subdivisé en trois chapitres principaux, reprenant les trois grandes phases de la gestion d’un projet CRM (phase de conception du projet, phase de développement, phase d’implémentation et d’utilisation). Chaque chapitre présente de façon détaillée l’étape en question, en invitant le gestionnaire de projet à s’insérer dans un fil conducteur de pensée et en lui présentant différents outils et méthodologies pour conduire ses réflexions. Il est néanmoins à noter que les différents chapitres et éléments de ce guide, séparés pour des raisons de présentation, ne doivent pas être perçus comme décloisonnés et indépendants les uns des autres ; ils sont au contraire reliés entre eux au travers d’une approche processuelle de la gestion de projet. Les démarches présentées veillent à ce que soient systématiquement pris en compte, étape par étape, les différents axes de la gestion d’un projet de cette envergure, à savoir les éléments stratégiques, technologiques, organisationnels et humains liés à la gestion d’un projet CRM. Celles-ci sont de plus appuyées de différents arguments, justifiant les raisons sous-jacentes à la nécessité de les mener à bien pour le bon déroulement du projet. Elles sont également reliées à des fiches méthodologiques et d’exercices, reprises en annexes, que les responsables de projets CRM pourront mettre à profit dans la conduite de leurs réflexions. En outre, la lecture de ce guide se veut facilitée par la présentation régulière de schémas et synthèses permettant aux gestionnaires de projets de tirer des bilans réguliers sur la logique et l’état d’avancement de leurs réflexions. Ces derniers trouveront également, en cours de texte, différents exemples de situations rencontrées dans des PME confrontées à la gestion d’un projet de ce type. Ces exemples – s’avérant parfois être davantage des "contre-exemples" – sont mis à profit pour illustrer les concepts de ce guide et mettre en évidence certaines difficultés auxquelles ont fait face des PME dans leur démarche d’implantation d’un projet CRM. [less ▲]

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See detailConséquences de la chirurgie de transposition du muscle grand dorsal
Forthomme, Bénédicte ULg; Heymans, Olivier; Grandjean, François-Xavier ULg et al

in Abstract book de la 5ème Journée Belge d’Isocinétisme du GIBL (2005, December)

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See detailIntérêt de l’exercice excentrique dans le traitement de l’épicondylite chronique
Croisier, Jean-Louis ULg; Foidart-Dessalle, Marguerite ULg; Crielaard, Jean-Michel ULg et al

in Abstract book de la 5ème Journée Belge d’Isocinétisme du GIBL (2005, December)

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See detailThe use of mathematical symbolism in problem solving : an empirical study carried out in grade one in the French Community of Belgium
Fagnant, Annick ULg

in European Journal of Psychology of Education (2005), XX(4), 355-367

This article relates to an empirical study based on the use of mathematical symbolism in problem solving. Twenty-five pupils were interviewed individually at the end of grade one; each of them was asked ... [more ▼]

This article relates to an empirical study based on the use of mathematical symbolism in problem solving. Twenty-five pupils were interviewed individually at the end of grade one; each of them was asked to solve and symbolize 14 different problems. In their classical curriculum, these pupils have received a traditional education based on a "top-down" approach (an approach that is still applied within the French Community of Belgium): conventional symbols are presented to the pupils immediately with an explanation of what they represent and how they should be used. Teaching then focuses on calculation techniques (considered as a pre-requisite for solving problems). The results presented here show the abilities (and difficulties) demonstrated by the children in making connections between the conventional symbolism taught in class and the informal approaches they develop when faced with the problems that arc, put to them. The limits of the "top-down" approach are then discussed as opposed to the more innovative "bottom-up" type approaches, such as those developed by supporters of Realistic Mathematics Educations in particular. [less ▲]

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See detailExigences physiologiques necessaires a la pratique de la gymnastique de haut niveau
Lange, B.; Halkin, Anne-Sophie ULg; Bury, Thierry ULg

in Revue Médicale de Liège (2005), 60(12), 939-45

The evolution of the physiological profile of gymnasts over the past 40 years is outlined. Generally, gymnasts have a low aerobic aptitude in spite of an increase in the number of training hours. During ... [more ▼]

The evolution of the physiological profile of gymnasts over the past 40 years is outlined. Generally, gymnasts have a low aerobic aptitude in spite of an increase in the number of training hours. During the last decades, anaerobic power of gymnasts has increased. And now, the maximal power output measured by the Wingate test in high level male gymnasts is between 12 and 14 W.Kg-1 and in female gymnasts between 10 and 12 W.Kg-1. Measurement of higher blood lactate values also confirms that the anaerobic capacity has increased. [less ▲]

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See detailHepatitis C virus genotype 5 in southern Belgium: Epidemiological characteristics and response to therapy
Delwaide, Jean ULg; Gerard, Christiane ULg; Reenaers, Catherine ULg et al

in Digestive Diseases & Sciences (2005), 50(12), 2348-2351

Data are scarce on patients infected with hepatitis C virus of genotype 5, due to the low prevalence of this genotype around the world. To better define the characteristics of these patients, we reviewed ... [more ▼]

Data are scarce on patients infected with hepatitis C virus of genotype 5, due to the low prevalence of this genotype around the world. To better define the characteristics of these patients, we reviewed the files of 16 genotype 5 patients. Mean age was 38 +/- 14. All patients were of European origin. Most of them (75%) had been contaminated by transfusion within a short time period (between 1980 and 1991). There were no intravenous drug addicts. Seven patients received treatment. One patient did not respond to interferon (IFN) monotherapy. Of four patients treated with IFN and ribavirin, three became sustained viral responders. Two patients treated with pegylated IFN and ribavirin became sustained viral responders. In our region, genotype 5 patients seem to have been contaminated within a relatively short time period. Treatment with IFN or pegylated IFN and ribavirin gave a high rate (83%) of sustained viral responses. [less ▲]

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See detailTuareg ethnodiagnostic skill of camel diseases in Agadez area (Niger)
Antoine-Moussiaux, Nicolas ULg; Faye, Bernard; Vias, Gilles F.

in Journal of Camel Practice and Research (2005), 12(2), 85-93

For generations, nomad herders have been learning to manage herd health, particularly in dromedary because of its high value. They have thus acquired a very comprehensive knowledge of camel's illness ... [more ▼]

For generations, nomad herders have been learning to manage herd health, particularly in dromedary because of its high value. They have thus acquired a very comprehensive knowledge of camel's illness signs and have developed their own nomenclature. The present study aims at the description, scientific identification and recognition of this ethnoveterinary knowledge by means of an investigation carried out in Tuareg populations living in the neighbourhoods of Agadez (Niger). The dominant pathologies cited by herders for being the most alarming are gastro-intestinal helminthiasis (izni), camel calf diarrhoea (efay), tick infestations of camel calves (igardan), camel pox (erk eshik), sarcoptic mange (ajud) and bronchopneumonia (toza). Poorly identified nosologic entities are also reported. [less ▲]

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