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See detailNotes de lecture sur l’ouvrage "Pour une histoire culturelle du cinéma"
Tomasovic, Dick ULg

in 1895 : Bulletin de l'Association Française de Recherche sur l'Histoire du Cinéma (2004), 44

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See detailPISA 2003 : Quels défis pour notre système éducatif ?
Baye, Ariane ULg; Demonty, Isabelle ULg; Fagnant, Annick ULg et al

E-print/Working paper (2004)

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See detailHoe staan vreemdelingen en allochtonen tegenover recht en gerecht in België?
Martiniello, Marco ULg; Foblets, Marie-Claire; Parmentier, Stephan et al

in Rechtskundig Weekblad (2004), 68(16), 601-617

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See detailApplication of magnetic susceptibility in sedimentology
Da Silva, Anne-Christine ULg

Scientific conference (2004, December)

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See detailRisk factors for first-ever low back pain among workers in their first employment
Van Nieuwenhuyse, A.; Fatkhutdinova, L.; Verbeke, G. et al

in Occupational Medicine-Oxford (2004), 54(8), 513-519

Background Low back pain has been estimated to be the most costly ailment of people of working age. Both work characteristics and individual factors have been identified as risk factors. The first ... [more ▼]

Background Low back pain has been estimated to be the most costly ailment of people of working age. Both work characteristics and individual factors have been identified as risk factors. The first interaction between work characteristics and individual factors occurs when workers start in their first job. Aims To investigate work-related risk factors for first-ever low back pain in young workers in their first employment. Methods A cross-sectional analysis was performed on 278 young workers in their first employment and without a history of low back pain prior to working. Work-related physical factors, psychosocial work characteristics, individual variables and first-ever low back pain were queried by means of a questionnaire. Results About half of the workers who developed low back pain after job start did so in the first year of employment. An increased risk was observed for (i) long periods of seated work [relative risk (RR) = 3.2, 95% confidence interval (CI) = 1.6-6.4]; (ii) more than 12 flexion or rotation movements of the trunk per hour (RR = 3.0, 95% CI = 1.4-6.4); and (iii) more than 3 years seniority in a job involving lifting more than 25 kg at least once an hour (RR = 3.7, 95% CI = 1.4-9.4). As to psychosocial work characteristics, first-ever low back pain was associated with a combination of low psychological job demands and low supervisor support. Conclusion Work-related physical factors and psychosocial work characteristics should be considered as risk factors for first-ever low back pain. First-ever episodes of low back pain are common in the first year of employment. This may reflect a lack of work experience or training. [less ▲]

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See detailHard X-ray emission clumps in the gamma-Cygni supernova remnant: An INTEGRAL-ISGRI view
Bykov, A. M.; Krassilchtchikov, A. M.; Uvarov, Y. A. et al

in Astronomy and Astrophysics (2004), 427(3), 21-24

Spatially resolved images of the galactic supernova remnant G78.2+2.1 (gamma-Cygni) in hard X-ray energy bands from 25 keV to 120 keV are obtained with the IBIS-ISGRI imager aboard the International Gamma ... [more ▼]

Spatially resolved images of the galactic supernova remnant G78.2+2.1 (gamma-Cygni) in hard X-ray energy bands from 25 keV to 120 keV are obtained with the IBIS-ISGRI imager aboard the International Gamma-Ray Astrophysics Laboratory INTEGRAL. The images are dominated by localized clumps of about ten arcmin in size. The flux of the most prominent North-Western (NW) clump is (1.7+/-0.4)x10(-11) erg cm(-2) s(-1) in the 25-40 keV band. The observed X-ray fluxes are in agreement with extrapolations of soft X-ray imaging observations of gamma-Cyg by ASCA GIS and spatially unresolved RXTE PCA data. The positions of the hard X-ray clumps correlate with bright patches of optical line emission, possibly indicating the presence of radiative shock waves in a shocked cloud. The observed spatial structure and spectra are consistent with model predictions of hard X-ray emission from nonthermal electrons accelerated by a radiative shock in a supernova interacting with an interstellar cloud, but the powerful stellar wind of the O9V star HD 193322 is a plausible candidate for the NW source as well. [less ▲]

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See detailPhylogeny, biogeography, and the evolution of life-history traits in Leucadendron (Proteaceae)
Barker, N. P.; Vanderpoorten, Alain ULg; Morton, C. M. et al

in Molecular Phylogenetics and Evolution (2004), 33(3), 845-860

Leucadendron is a moderately large genus of Proteaccae almost entirely restricted to the Cape Floristic Region of southern Africa. The genus is unusual in being dioecious and sexually dimorphic. ITS ... [more ▼]

Leucadendron is a moderately large genus of Proteaccae almost entirely restricted to the Cape Floristic Region of southern Africa. The genus is unusual in being dioecious and sexually dimorphic. ITS sequence data were obtained from 62 of the 96 currently recognized taxa (85 species and 11 subspecies). Phylogenetic analyses were conducted under Maximum Likelihood and parsimony and resolved nine groups of species with varying degrees of bootstrap support, but relationships between these groups are largely unsupported. The phylogeny conflicts with the current taxonomic arrangement, which is based mainly on fruit morphology. The two sections of the genus, Alatosperma and Leucadendron, and several subsections within these sections, are resolved as non-monophyletic. This means that taxonomically important characters (such as fruit shape) have evolved multiple times, as the species with nutlike fruit (resolved into two of the nine groups) appear to have evolved independently from ancestors with winged fruit. Based on the topology obtained, the life history traits of anemophily, myrmechochory, and re-sprouting have also originated multiple times. Dispersal-Vicariance (DIVA) analysis suggests that the genus had an ancestral area in the Karoo Mountain and Southeastern phytogeographic centres of endemism in the southwestern Cape. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailNo influence of 20 and 400 mu T 50 Hz magnetic field exposure on cognitive function in humans
Delhez, Marie; Legros, Jean-Jacques ULg; Crasson, Marion ULg

in Bioelectromagnetics (2004), 25(8), 592-598

The aim of the present study was to investigate cognitive effects of a continuous, vertical extremely low frequency (ELF) magnetic field (MF) of 20 and 400 muT 50 Hz in healthy young men during ... [more ▼]

The aim of the present study was to investigate cognitive effects of a continuous, vertical extremely low frequency (ELF) magnetic field (MF) of 20 and 400 muT 50 Hz in healthy young men during performance on cognitive tests. Thirty-two volunteers (20-30 years old, mean 22.6 +/- 2.2 years) participated in this double blind study. The test protocol consisted of a set of tests: divided attention, flexibility, memory updating, digit span, digit span with articulary suppression, and time perception. The total duration of the exposure was 65 min. Participants were assigned four sessions: three conditions in the helmet (sham exposure, 20 and 400 muT) and one condition out of the helmet (to control the expectancy effect). No effect of MF exposure was observed on performance. Bioelectromagnetics 25:592-598, 2004. (C) 2004 Wiley-Liss, Inc. [less ▲]

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See detailNumber of iterations when comparing MLEM/OSEM with FBP
Seret, Alain ULg

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (2004), 45(12), 2125-2125

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See detailOxytocin- and vasopressin-induced growth of human small-cell lung cancer is mediated by the mitogen-activated protein kinase pathway
Pequeux, Christel ULg; Keegan, B. P.; Hagelstein, M. T. et al

in Endocrine-Related Cancer (2004), 11(4), 871-885

Malignant growth of small-cell lung carcinoma is promoted by various neuroendocrine autocrine/paracrine loops. Therefore, to interfere with this mitogenic process, it is crucial to elucidate the ... [more ▼]

Malignant growth of small-cell lung carcinoma is promoted by various neuroendocrine autocrine/paracrine loops. Therefore, to interfere with this mitogenic process, it is crucial to elucidate the mechanisms involved. It is known that the oxytocin (OT) and vasopressin (VP) genes, normally transcriptionally restricted in their expression, are activated in small-cell lung cancer (SCLC), concomitantly with expression of their receptors (OTR, V1aR, V1bR/V3R and V2R). The aim of the present study was to characterize, in concentrations close to physiological and pharmacological conditions, intracellular signalling events triggered by OT and VP binding to their specific receptors in SCLC cells and to identify factors mediating OT- and VP-induced mitogenic effects on SCLC. Known agonists for OTR ([Thr(4),GlY(7)]OT) and V1aR (F180), in addition to OT and VP, were able to elicit increases in cytosolic Ca2+ levels and this effect could be blocked using an OTR antagonist (OVTA) or a V1aR antagonist (SR49059) respectively. There was no activation of the cAMP pathway detected after VP, dDAVP (a V2R agonist), or OT treatment. Stimulation of SCLC cells with OT and VP led to an increase of extracellular signal-regulated kinase (ERK) 1/2 phosphorylation, maximal at 5 min, and the subsequent phosphorylation of its downstream target p90 ribosomal S6 kinase (p90(RSK)). Pre-incubation with OVTA and SR49059, and with inhibitors of phospholipase C (PLC), protein kinase C (PKC), mitogen-activated protein kinase/ERK kinase (MEK) 1/2 and a Ca2+ chelator significantly reduced OT- and VP-induced ERK1/2 phosphorylations. OVTA, SR49059 as well as MEK1/2 and PKC inhibitors also downregulated OT- and VP-induced p90RSK phosphorylation. In [H-3]thymidine-uptake 2, experiments, we subsequently observed that PLC, Ca2+, PKC and ERK1/2 are absolutely required for the OT- and VP-stimulated SCLC cellular growth process. In conclusion, the results presented here indicate that OT- and VP-induced mitogenic effects on SCLC are respectively mediated by OTR and V1aR signalling and that this mitogenic signalling passes through the phosphorylation of ERK1/2 and p90(RSK) in a PLC-, Ca2+-, PKC- and MEK1/2-dependent pathway. [less ▲]

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See detailPhenomenal characteristics associated with projecting oneself back into the past and forward into the future: Influence of valence and temporal distance
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg

in Consciousness & Cognition (2004), 13(4), 844-858

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience ... [more ▼]

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience associated with remembering the past and imagining the future. Participants mentally "re-experienced" or "pre-experienced" positive and negative events that differed in their temporal distance from the present (close versus distant), and then rated the phenomenal characteristics (i.e., sensorial, contextual, and emotional details) associated with their representations. For both past and future, representations of positive events were associated with a greater feeling of re-experiencing (or pre-experiencing) than representations of negative events. In addition, representations of temporally close events (both past and future) contained more sensorial and contextual details, and generated a stronger feeling of re-experiencing (or pre-experiencing) than representations of temporally distant events. It is suggested that the way we both remember our past and imagine our future is constrained by our current goals. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailProtein phosphorylation as a key mechanism for the regulation of BCL-3 activity
Viatour, Patrick ULg; Merville, Marie-Paule ULg; Bours, Vincent ULg et al

in Cell Cycle (Georgetown, Tex.) (2004), 3(12), 1498-1501

Constitutive NF-kappaB activation, a hallmark of many human cancers, upregulates anti-apoptotic gene expression and therefore disrupts the balance between apoptosis and proliferation. In some lymphomas ... [more ▼]

Constitutive NF-kappaB activation, a hallmark of many human cancers, upregulates anti-apoptotic gene expression and therefore disrupts the balance between apoptosis and proliferation. In some lymphomas, this constitutive NF-kappaB activity is the result of point mutations or translocations of the genes coding for NF-kappaB inhibitors, namely IkappaBalpha or p100. The BCL-3 protein is another member of the IkappaB family and is overexpressed in a subset of human B-cell chronic lymphocytic leukemias because of a chromosomal translocation. This oncoprotein is phosphorylated by multiple kinases including GSK3 and this phosphorylation regulates BCL-3 function by modulating its oncogenic potential and by regulating the expression of a subset of its target genes. Therefore, deciphering the NF-kappaB/IkappaB protein phosphorylations is critical in order to better understand the molecular mechanisms of NF-kappaB-mediated oncogenesis. [less ▲]

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See detailShaker-type potassium channel subunits differentially control oligodendrocyte progenitor proliferation
Vautier, Francois; Belachew, Shibeshih ULg; Chittajallu, Ramesh et al

in Glia (2004), 48(4), 337-345

Oligodendrocyte precursor (OP) cells are exposed to multiple extrinsic signals that control their proliferation and differentiation. Previous cell proliferation studies and electrophysiological analysis ... [more ▼]

Oligodendrocyte precursor (OP) cells are exposed to multiple extrinsic signals that control their proliferation and differentiation. Previous cell proliferation studies and electrophysiological analysis in cultured cells and in brain slices have suggested that outward potassium channels, particularly Kv1 subunits, may have a prominent role in OP cell proliferation. In the present study, we assessed to what extent overexpression of Kv1.3, Kv1.4, Kv1.5, and Kv1.6 can affect OP cell proliferation and differentiation in culture. We observed that overexpression of Kv1.3 or Kv1.4 increased OP cell proliferation in the absence of mitogens, whereas Kv1.6 overexpression inhibited mitogen-induced OP cell cycle progression. Interestingly, Kv1.3, Kv1.4, Kv1.5, and Kv1.6 overexpression did not interfere with the kinetics of oligodendrocyte differentiation. This study represents the first demonstration that the activity of potassium channels containing distinct Kv1 subunit proteins directly controls oligodendroglial proliferation in the presence of mitogens, as well as in growth factor-free conditions. (C) 2004 Wiley-Liss, Inc. [less ▲]

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See detailUnusual thermoelectric behavior of packed crystalline granular metals
Ausloos, Marcel ULg; Pekala, Marek; Latuch, J. et al

in Journal of Applied Physics (2004), 96(12), 7338-7345

Loosely packed granular materials are intensively studied nowadays. Electrical and thermal transport properties should reflect the granular structure, as well as intrinsic properties. We have compacted ... [more ▼]

Loosely packed granular materials are intensively studied nowadays. Electrical and thermal transport properties should reflect the granular structure, as well as intrinsic properties. We have compacted crystalline CaAl-based metallic grains and studied the electrical resistivity and the thermoelectric power as a function of temperature (T) from 15 to 300 K. Both properties show three regimes as a function of temperature. It should be pointed out: (i) The electrical resistivity continuously decreases between 15 and 235 K, (ii) with various dependencies, e.g., similar ~ T(-3/4) at low T, while (iii) the thermoelectric power (TEP) is positive, (iv) shows a bump near 60 K, and (v) presents a rather unusual square root of temperature dependence at low temperature. It is argued that these three regimes indicate a competition between geometric and thermal processes-for which a theory seems to be missing in the case of TEP. The microchemical analysis results are also reported, indicating a complex microstructure inherent to the phase diagram peritectic intricacies of this binary alloy. (C) 2004 American Institute of Physics. [less ▲]

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See detailZerebrale Funktionen bei hirngeschädigten Patienten. Was bedeuten Koma, "vegetative state“, "minimally conscious state“, "Locked-in-Syndrom“ und Hirntod?
Faymonville, Marie-Elisabeth ULg; Pantke, Karl-Heinz; Berré, Jacques et al

in Anaesthesist (2004), 53(12), 1195-1202

Comatose, vegetative, minimally conscious or locked-in patients represent a problem in terms of diagnosis, prognosis, treatment and everyday management at the intensive care unit. The evaluation of ... [more ▼]

Comatose, vegetative, minimally conscious or locked-in patients represent a problem in terms of diagnosis, prognosis, treatment and everyday management at the intensive care unit. The evaluation of possible cognitive functions in these patients is difficult because voluntary movements may be very small, inconsistent and easily exhausted. Functional neuroimaging cannot replace the clinical assessment of patients with altered states of consciousness. Nevertheless, it can describe objectively how deviant from normal the cerebral activity is and its regional distribution at rest and under various conditions of stimulation. The quantification of brain activity differentiates patients who sometimes only differ by a brief and incomplete blink of an eye. In the present paper, we will first try to define consciousness as it can be assessed at the patient's bedside. We then review the major clinical entities of altered states of consciousness encountered in the intensive care unit. Finally, we discuss the functional neuroanatomy of these conditions as assessed by positron emission tomography (PET) scanning. [less ▲]

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See detailComputer modeling of restrained reinforced concrete slabs in fire conditions
Lim, Linus; Buchanan, Andrew; Moss, Peter et al

in Journal of Structural Engineering (2004), 130(12), 1964-1971

This paper describes the computer modeling of axially restrained, one-way reinforced concrete slabs in fire conditions. The study was carried out for slabs with pin supports and slabs with rotationally ... [more ▼]

This paper describes the computer modeling of axially restrained, one-way reinforced concrete slabs in fire conditions. The study was carried out for slabs with pin supports and slabs with rotationally restrained supports. A single span, 5 m slab, carrying a uniformly distributed load was analyzed using a special purpose, nonlinear finite element program, SAFIR. The study for pin-supported slabs considered the effects of the position of the thrust force at the supports and different axial restraint stiffnesses. The effects of axial restraint on slabs with rotationally restrained supports were also investigated. The analyses found that the behavior of pin-supported slabs is very sensitive to the position of the thrust force at the end supports and the axial restraint stiffnesses. Slabs with rotationally restrained supports are predicted to have much better fire resistance than equivalent pin-supported slabs due to moment redistribution. The behavior of rotationally restrained slabs in fire conditions is less sensitive to the different axial restraint stiffnesses than pin supported slabs. [less ▲]

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See detailCharacterization of inulin stored at different relative humidities by MDSC and X-ray diffraction, related to soption isotherms.
Ronkart, Sébastien; Fougnies, C.; Paquot, Michel ULg et al

Poster (2004, December)

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