References of "2004"
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See detailPositive interactive radiosensitization observed in vitro with the combination of two nucleoside analogs (E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC) and iododeoxyuridine (IdUrd).
Coucke, Philippe ULg; Cottin, E; Azria, D et al

in European Journal of Cancer (2004)

(E)-20-Deoxy-20-(fluoromethylene) cytidine (FMdC), an inhibitor of ribonucleotide diphosphate reductase (RR), is a potent radiation-sensitiser acting through alterations in the deoxyribonucleoside ... [more ▼]

(E)-20-Deoxy-20-(fluoromethylene) cytidine (FMdC), an inhibitor of ribonucleotide diphosphate reductase (RR), is a potent radiation-sensitiser acting through alterations in the deoxyribonucleoside triphosphate (dNTP) pool in the de novo pathway to DNA synthesis. The activity of thymidine kinase (TK), a key enzyme in the ‘salvage pathway’, is known to increase in response to a lowering of dATP induced by FMdC. Nucleoside analogues such as iododeoxyuridine (IdUrd) are incorporated into DNA after phosphorylation by TK. Radiation sensitisation by IdUrd depends on IdUrd incorporation. Therefore, we have investigated the radiosensitising effect of the combination of FMdC and IdUrd on WiDr (a human colon cancer cell-line) and compared it to the effect of either drug alone. We analysed the effects of FMdC and IdUrd on the dNTP pools by high-performance liquid chromatography, and measured whether the incorporation of IdUrd was increased by FMdC using a [125I]-IdUrd incorporation assay. The combination in vitro yielded radiation-sensitiser enhancement ratios of >2, significantly higher than those observed with FMdC or IdUrd alone. Isobologram analysis of the combination indicated a supra-additive effect. This significant increase in radiation sensitivity with the combination of FMdC and IdUrd could not be explained by changes in the dNTP pattern since the addition of IdUrd to FMdC did not further reduce the dATP. However, the increase in the radiation sensitivity of WiDr cells might be due to increased incorporation of IdUrd after FMdC treatment. Indeed, a specific and significant incorporation of IdUrd into DNA could be observed with the [125I]-IdUrd incorporation assay in the presence of 1 lM unlabelled IdUrd when combined with FMdC treatment. 2004 Elsevier Ltd. All rights reserved. [less ▲]

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See detailA three-month course of depot octreotide in the treatment of Graves' orbitopathy : clinical results of a randomized placebo-controlled double-blind study
Wémeau, J. L.; Beckers, Albert ULg; Caron, P. et al

in 12th International Congress of Endocrinology - Abstract book (2004)

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See detailTraitement structurel de l'arthrose : le point en 2004
Reginster, Jean-Yves ULg; LECART, Marie-Paule ULg; SARLET, Nathalie ULg

in Ortho-Rhumato (2004), 2(3), 52-54

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See detailLe Haricot-igname Africain (Sphenostylis stenocarpa (Hochst. ex A. Rich.) Harms) : une légumineuse à graines et à tubercules sous-exploitée
Baudoin, Jean-Pierre ULg; Kamion Ngansia, F.

in Troupeaux et Cultures des Tropiques (2004), II(IV), 44-46

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See detailDes socles de compétences à la mise en place d'une démarche expérimentale à l'école primaire : intervention en formation initiale des enseignants
Hindryckx, Marie-Noëlle ULg; Graftiau, Marie-Christine; Stegen, Pierre

in Actes du Troisième Congrès des chercheurs e, Education (Re)trouver le plaisir d'enseigner et d'apprendre ; construire savoirs et compétences (2004)

recherche action menée en collaboration entre deux services universitaires et la Haute Ecole Charlemagne de Liège autour de la formation initiale des enseignants du primaire en sciences. Interventions ... [more ▼]

recherche action menée en collaboration entre deux services universitaires et la Haute Ecole Charlemagne de Liège autour de la formation initiale des enseignants du primaire en sciences. Interventions dans le cadre des ateliers de formation professionnelle [less ▲]

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See detailCompte rendu de l'ouvrage de M. Hénaff : Le prix de la vérité
Cormann, Grégory ULg

in Etudes Philosophiques (2004), 3

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See detailEffet de prétraitements agoniste et antagoniste de GnRH sur la production d’embryons chez la brebis et la chèvre
Baril, G.; Cognié, Y.; Belloc, J. P. et al

in Proceedings: 11e Rencontres autour des Recherches sur les Ruminants (3R) (2004)

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See detailCan dust variability be a regional indicator of land degradation trend in arid and semi-arid areas? Analysis in the Sahel.
Ozer, Pierre ULg

in Demarée, Gaston; De Dapper, Morgan; Alexandre, Jean (Eds.) Tropical Climatology, Meteorology and Hydrology: Climate-related risk analysis and sustainable development in tropical areas. (2004)

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See detailSpontaneous arachnoid cyst rupture in a previously asymptomatic child: a case report
Poirrier, Anne-Lise ULg; Ngosso-Tetanye, I.; Mouchamps, M. et al

in European Journal of Paediatric Neurology : Official Journal of the European Paediatric Neurology Society (2004), 8(5), 247-251

Arachnoid cysts are benign congenital cavities arising in the subarachnoid space. Non-traumatic subdural effusion of cerebrospinal fluid is a rare complication requiring surgical treatment. Case Report: A ... [more ▼]

Arachnoid cysts are benign congenital cavities arising in the subarachnoid space. Non-traumatic subdural effusion of cerebrospinal fluid is a rare complication requiring surgical treatment. Case Report: A 15-year-old boy was admitted to the hospital because of symptoms related to acute intracranial hypertension (headache and vomiting). The cerebral CT-scan revealed a subdural hygroma adjoining a voluminous Sylvian arachnoid cyst. Two arachnoid cysts were incidentally discovered 11 years before this dramatic complication. Moreover, the patient had suffered a cerebral concussion 2 years earlier, but interestingly did not develop cystic hemorrhage or rupture, contrary to numerous cases previously described in the literature. The location of the cysts and their regular follow-up did not allow foreseeing a cystic rupture. Hygroma evacuation was first performed after which a subdural peritoneal. shunting, using a programmable opening pressure valve, was implanted. Spontaneous rupture into the subdural space represents an unusual complication of arachnoid cysts. Clinical aspects, radiographic findings, pathogenesis and surgical management are described. It is important to point out that subdural hygroma or haematoma should never be excluded in the absence of trauma history, even in the case of small non-progressive cysts regularly supervised. (C) 2004 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved. [less ▲]

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See detailMorsures et griffures des chats, chiens et rats : étiologies et attitude
Mainil, Jacques ULg

Learning material (2004)

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See detailLe management des connaissances: une révolution pour la GRH?
Robert, Jocelyne ULg

Article for general public (2004)

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See detailRelatif de liaison et temps verbaux chez les historiens latins
Longrée, Dominique ULg

Scientific conference (2004)

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See detailEarly neurophysiological diagnosis of true neurogenic « thoracic outlet syndrome » (TOS)
HUA, MT; DUBUISSON, Annie ULg; Zeevaert, Bernard et al

in Journal of Neurology (2004)

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See detailThe Same, Yet Different: Caryl Phillips's Screen Adaptation of V.S. Naipaul's The Mystic Masseur
Ledent, Bénédicte ULg

in Misrahi-Barak, Judith (Ed.) V.S. Naipaul: A World in Tension / Une oeuvre sous tension (2004)

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See detailPrediction of distortion during cooling of steel rolled rings using thermal-mechanical-metallurgical finite element model
Pascon, Frédéric ULg; Blès, Guilhem; Bouffioux, Chantal ULg et al

in Steel Grips 2 (2004), Supplement Metal Forming 1-3

This work takes place in the framework of a CRAFT European project gathering three universities, three companies who produce rings through the ring rolling process and a manufacturer of temperature and ... [more ▼]

This work takes place in the framework of a CRAFT European project gathering three universities, three companies who produce rings through the ring rolling process and a manufacturer of temperature and dimension measurement devices. The final goal of the project is to develop and set up a system, integrated in the industrial process, capable of predicting the geometrical characteristics of final pieces just after the ring rolling stage and to allow the rolling process to avoid dimensional defects through online adaption. In fact, ring rolling production does not imply only the rolling process, but also the cooling and quench stages of steel rings. During all these phases, the dimensions of the pieces change dramatically. In particular, due to the lack of symmetry in the cooling conditions, ring distortions include contraction and rotation of the ring section. The modeling of the cooling phase requires taking into account a large number of phenomena resulting from the coupling of thermal, mechanical and metallurgical effects. A numerical model has been implemented in the non-linear finite element code LAGAMINE, developed by the University of Liège. Such a model can help to better understand the evolution of the geometry during the cooling phase and also the effects of each physical and microstructural parameter implemented in the model on the ring final shape. Effectively, several parameters can affect the ring distortions and the model should take them into account; in particular, the mechanical and thermal behavior of each phase present in the material (metastable austenite, ferrite, pearlite, bainite and martensite). Phase transformation modeling implies the integration of a wide data base of material properties (thermo-physical and mechanical properties of the phases, TTT and CCT diagrams, enthalpy and strain of phase transformation, strain of transformation plasticity…) but only a few of these data are available in literature. Some of them have been found for the reference material (42CrMo4 steel), but additional laboratory experiments have been performed at the Universities of Padua and Liège in order to characterize thermal, mechanical and plastic behaviour of phases. Finally, this paper presents the model validation on an industrial case (measurements of temperature and dimensions of rings have been provided by the manufacturer). Then, some applications are presented, demonstrating the importance of some factors such as some material properties, the shape of the rings, the type of cooling (and the cooling rate) or the symmetry of the cooling scheme on final ring distortion. [less ▲]

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See detailLe genre Strigula (Lichens) en Europe et en Macaronésie
Roux, Claude; Sérusiaux, Emmanuël ULg

in Bibliotheca Lichenologica (2004), 90

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See detailLes obligations : concepts financiers et comptables essentiels
Colmant, Bruno ULg; Delfosse, Vincent ULg; Esch, Louis ULg

Book published by De Boeck et Larcier - 2ème éd. (2004)

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See detailTerrestrial versus aquatic foraging in juvenile Alpine newts (Triturus alpestris)
Denoël, Mathieu ULg

in Ecoscience (2004), 11(4), 404-409

Many species of newts and salamanders forage in both terrestrial and aquatic environments during their life. However, the relative benefits of the two foraging patterns remain unknown because all previous ... [more ▼]

Many species of newts and salamanders forage in both terrestrial and aquatic environments during their life. However, the relative benefits of the two foraging patterns remain unknown because all previous studies have focused on only one habitat. The aim of this study was to find out which foraging tactic is the most successful in terms of energy intake. To this end, I analyzed trophic habits in metamorphosed juveniles in the Alpine newt, Triturus alpestris veluchiensis, inhabiting an alpine lake (Drakolimni) and the surrounding lands (Tymphi Mountains, northern Greece). The diet of the newts reflected the range of prey available in the two habitats, but aquatic newts also foraged on invertebrates that fell on the water surface. The two lifestyles have different energy outcomes. Terrestrial invertebrates provided high energy gains mainly to terrestrial juveniles because of the low number of this prey type in the lake. However, terrestrial juveniles are expected to suffer higher mortality (freezing on land is more probable than in deep waters) and a lower energy intake when air temperature is low, i.e., the main pattern in high-elevation sites, except during mid-summer. Persistence of the aquatic foraging tactics in the population may depend on a trade-off between costs and benefits. [less ▲]

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See detailProposition d’une méthode de typologie hydro-géomorphologique des cours d’eau et tes sur un sous-bassin du Rhône (Bassin de l’Yzeron).
Schmitt, Laurent; Valette, L.; Valin, K. et al

in MOSELLA, XXIX (3-4) (2004)

Proposal of a method of hydro-geomorphological typology of rivers and test of a sub-basin of the Rhône River (Yzeron basin). The paper proposes a hydro-geomorphological typology method of watercourses ... [more ▼]

Proposal of a method of hydro-geomorphological typology of rivers and test of a sub-basin of the Rhône River (Yzeron basin). The paper proposes a hydro-geomorphological typology method of watercourses that might potentially be used in western Europe. The method was tested in the Yzeron basin (France). Field data were collected and analysed by multivariate statistics. Statistical results were consistent with the results of the typology model. Some recommendations are also made for the future development of automatic methods of characterization-sectorization of rivers. [less ▲]

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