References of "2004"
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See detailIs ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol
Quertemont, Etienne ULg; Tambour, Sophie ULg

in Trends in Pharmacological Sciences (2004), 25(3), 130-134

Acetaldehyde, the first product of ethanol metabolism, has been speculated to be involved in many behavioral effects of ethanol. However, its precise role remains a matter of debate, with some researchers ... [more ▼]

Acetaldehyde, the first product of ethanol metabolism, has been speculated to be involved in many behavioral effects of ethanol. However, its precise role remains a matter of debate, with some researchers suggesting that acetaldehyde has no role in the effects of ethanol and others contending that ethanol is a pro-drug whose pharmacological action is mediated by acetaldehyde. Recent studies support a role for acetaldehyde in the stimulant, reinforcing, hypnotic and amnesic effects of ethanol, and, in particular, alcohol abuse and alcoholism. However, current evidence indicates that acetaldehyde is not involved in some of the major neurochemical effects of ethanol. It is therefore likely that ethanol and acetaldehyde molecules act synergistically to determine the multiple neurochemical and behavioral effects of alcohol consumption. [less ▲]

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See detailEntreprendre au féminin : une réalité multiple et des attentes différenciées
Cornet, Annie ULg; Constantinidis, Christina ULg

in Revue Française de Gestion (2004), 30(151),

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See detailHyperhidrose palmaire et axillaire.
Uhoda, Emmanuelle ULg; Pierard, Gérald ULg

in Dermatologie Actualité (2004), 84

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See detailNikki Santilli, Such Rare Citings
Delville, Michel ULg

in Sentence: A Journal of Prose Poetics (2004)

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See detailMeteor excitation and meteoroid abundances from quantitative spectroscopy
Jenniskens, P.; Laux, C. O.; Jehin, Emmanuel ULg

in 35th COSPAR Scientific Assembly (2004)

Meteor spectroscopy provides both quantitative data on the excitation conditions in the meteor plasma, the progressive ablation of mineral species in the meteoroid, and the meteoroid's elemental ... [more ▼]

Meteor spectroscopy provides both quantitative data on the excitation conditions in the meteor plasma, the progressive ablation of mineral species in the meteoroid, and the meteoroid's elemental abundances for selected elements. The recent NASA and USAF sponsored Leonid Multi-Instrument Aircraft Campaign provided high-resolution spectra of relatively faint meteors using a slit-less cooled CCD spectrograph. Additional observations from ground and space extended the wavelength range from 250 to 1050 nm. We have measured excitation conditions in the meteor plasma from studies of meteoric air plasma emissions (N_2, N, O, O_2) and ablated metal atom line emissions (Fe). Results were compared to laboratory calibrated air plasma emission models and LTE models of metal atom line emissions. Further insight was provided by a spectrum recorded serendipitously at the European Southern Observatory VLT telescope, which provides the first spectral information over a cross-section of a meteor trail. We also searched for emissions from CN, H, and OH that may be ablation products of organic matter and mineral water contained in the meteoroid. We will present an overview of the information gathered to date and discuss the meteoric metal atom abundances (Fe, Mg, Si, Na, Ca, Mn, Al, Ni, Ti, Sc, Cr, Co, and V) measured for representative meteoroids. [less ▲]

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See detailPolyamines in gut inflammation and allergy
Peulen, Olivier ULg; Deloyer, Patricia; Deville, Christelle ULg et al

in Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents (2004), 3

The natural polyamines, named 1,4-diaminobutane, N-aminopropyl-1,4-diaminobutane and N,N'-bisaminopropyl- 1,4-diaminobutane, are also designated respectively as putrescine, spermidine and spermine. They ... [more ▼]

The natural polyamines, named 1,4-diaminobutane, N-aminopropyl-1,4-diaminobutane and N,N'-bisaminopropyl- 1,4-diaminobutane, are also designated respectively as putrescine, spermidine and spermine. They are polycationic compounds found in all eukaryotic cells. As they are deeply involved in cell functions, e.g. cellular growth, their concentration and their equilibrium in the intracellular pool are maintained in very narrow limits by regulatory mechanisms acting in a very fast, sensitive and precise way. These compounds are involved in gut inflammatory processes and in allergy. Indeed, they control the production of inflammatory mediators in several cell lines or tissues. Polyamine metabolism could be considered as a putative target for inflammation, allergy prevention or therapy. [less ▲]

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See detailApproche clinique des suspicions d’insuffisance hépatique aiguë chez le cheval
Amory, Hélène ULg

in Pratique Vétérinaire Equine (2004), 36

Le diagnostic d’une insuffisance hépatique aigue chez le cheval n’est pas toujours aisé. Lorsqu’ils se manifestent, les signes cliniques présentés sont en effet en général peu spécifiques. Ils comprennent ... [more ▼]

Le diagnostic d’une insuffisance hépatique aigue chez le cheval n’est pas toujours aisé. Lorsqu’ils se manifestent, les signes cliniques présentés sont en effet en général peu spécifiques. Ils comprennent le plus souvent de la dépression, de l’anorexie et des signes d’hépatoencéphalopathie. D’autres signes moins fréquents ou moins spécifiques peuvent aussi être observés. La mise en place d’examens complémentaires est dans la plupart des cas nécessaire pour poser ou confirmer le diagnostic, bien que les résultats de ces derniers sont très variables en fonction des cas. Parmi ces examens, l’analyse de sang est le plus facile à mettre en œuvre sur le terrain. Les paramètres sanguins de caractérisation d’une insuffisance hépatique les plus utiles sont les enzymes "hépatiques", les sels biliaires, et la bilirubine totale et conjuguée. La biopsie constitue la technique de référence pour le diagnostic définitif des pathologies hépato-biliaires, ainsi que pour en établir le pronostic. Le traitement d’une insuffisance hépatique aigue chez le cheval a pour objectif principal de supporter la fonction hépatique et de réduire la production de métabolites toxiques au niveau du tractus gastro-intestinal jusqu’à ce qu’une régénération du tissu hépatique et une compensation de la fonction hépatique aient pu se mettre en place. [less ▲]

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See detailA functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.
Bottini, Nunzio; Musumeci, Lucia ULg; Alonso, Andres et al

in Nature Genetics (2004), 36(4), 337-8

We report that a single-nucleotide polymorphism (SNP) in the gene (PTPN22) encoding the lymphoid protein tyrosine phosphatase (LYP), a suppressor of T-cell activation, is associated with type 1 diabetes ... [more ▼]

We report that a single-nucleotide polymorphism (SNP) in the gene (PTPN22) encoding the lymphoid protein tyrosine phosphatase (LYP), a suppressor of T-cell activation, is associated with type 1 diabetes mellitus (T1D). The variants encoded by the two alleles, 1858C and 1858T, differ in a crucial amino acid residue involved in association of LYP with the negative regulatory kinase Csk. Unlike the variant encoded by the more common allele 1858C, the variant associated with T1D does not bind Csk. [less ▲]

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See detailEtude histologique du développement d'embryons issus du croisement Phaseolus vulgaris L. x P. coccineus L.
NGuema Ndoutoumou, P.; Toussaint, André ULg; Baudoin, Jean-Pierre ULg

Conference given outside the academic context (2004)

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See detailScale modelling and similarity laws for the study of an under pressure settling structure
Erpicum, Sébastien ULg; Dewals, Benjamin ULg; Archambeau, Pierre ULg et al

in Proceedings of the 9th International Symposium on River Sedimentation (2004)

This paper presents the scale model studies of a complex under pressure settling structure, carried out at the Laboratory of Hydraulic Constructions of the University of Liège. Made up of fourteen ... [more ▼]

This paper presents the scale model studies of a complex under pressure settling structure, carried out at the Laboratory of Hydraulic Constructions of the University of Liège. Made up of fourteen identical settling chambers placed side by side and the bottom of which is divided into pyramidal hoppers, the structure, totally under pressure, is fed by a vertical shaft. Downstream, the settling chambers discharge into a collector, which ensures the clean water feeding of four penstocks through a free surface basin. Finally, a pipes network, under the chambers, ensures the downstream evacuation of the sand trapped in the hoppers. Using adapted and theoretically justified similarity laws coupled with realistic scales for the models, the hydrodynamic behavior and solid transport phenomena in this complex system have been studied. Special care has been taken to evaluate the trap efficiency, the evacuation system working and the global discharge repartition between the fourteen chambers. Sawdust, plastic balls or very small sand particles have been used to model real sediments. A total of three models, from only one hopper to the full settling structure, have been built, with scales from 1/18.5 to 1/100. According to the results of the studies, the length of the settling chambers has been shortened of up to 38 meters, i.e. 2 hoppers, and best use instructions have been suggested for the sediment evacuation system. [less ▲]

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See detailVraies et fausses éditions liégeoises ou rouennaises de Voltaire
Droixhe, Daniel ULg

in Revue Voltaire (2004), 4

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See detailOn the collapse behaviour of oil reservoir chalk
De Gennaro, Vincenzo; Delage, Pierre; Priol, Grégoire et al

in Geotechnique (2004), 54(6), 415-420

Oil exploitation in North Sea Ekofisk oilfield started in 1971, the reservoir is located in a 150 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. Enhanced oil recovery procedure by sea water ... [more ▼]

Oil exploitation in North Sea Ekofisk oilfield started in 1971, the reservoir is located in a 150 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. Enhanced oil recovery procedure by sea water injection (waterflooding) was initiated in 1987. Starting from this date, seabed subsidence due to chalk compaction evolves at a fairly constant rate (i.e. 40 cm/year). Nowadays, the decrease of the seafloor level is of about 10 m. Reservoir management and production strategies are at the origin of the growing interest of petroleum industry in disposing of a comprehensive description of the chalk mechanical behaviour. In this note the subsidence due to waterflooding is interpreted within a framework taken from the mechanics of unsaturated soils. By considering oil as the non-wetting fluid and water as the wetting fluid, chalk compaction is depicted as a collapse phenomenon due to oil-water suction decrease. A series of suction controlled tests in the osmotic oedometer cell are presented. Water weakening effects and chalk compaction (collapse) seem likely to occur through the lost of strength of the inter-granular links existing in the oil saturated sample. The nature of these links includes both capillary and physico-chemical fluids-chalk interactions, and is well characterised by the oil-water suction. [less ▲]

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See detailMultispectral imaging of ore minerals in optical microscopy
Pirard, Eric ULg

in Mineralogical Magazine (2004), 68(2), 323-333

Multispectral imaging of ore minerals under the microscope is a logical extension of quantitative colour analysis and microspectrophotometric analysis of minerals. This paper describes, step by step, how ... [more ▼]

Multispectral imaging of ore minerals under the microscope is a logical extension of quantitative colour analysis and microspectrophotometric analysis of minerals. This paper describes, step by step, how the proper calibration of a scientific video camera can be performed in order to obtain precise reflectance measurements at each pixel within the field of view. After having reviewed the different sources of noise and aberration, practical formulae are presented that allow for the acquisition of a set of images at different wavelengths in the visible spectrum. The advantage of using a multispectral image acquisition system based on narrow bandwidth (10 nm) interference filters is discussed and quantitatively compared to colour imaging using tri-stimulus (red, green, blue) filters. Images taken from major sulphide parageneses are shown as examples of well contrasted multispectral images. Finally, the potential for automatic identification of ore minerals is discussed with reference to supervised multivariate image classification algorithms similar to those used in remote sensing. Additional comments on extending the principles for handling optical anisotropy and developing a multiradial imaging system are made. [less ▲]

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See detailFederal Risk Inventory, Survey and Knowledge building (FRISK)
Cornélis, Bernard; Brunet, Sébastien ULg; Juprelle, Pol

Report (2004)

1. Introduction Le projet FRISK (Federal Risk Inventory, Survey and Knowledge building) est une recherche commanditée par le Centre Gouvernemental de Coordination et de Crise (CGCCR) ou centre de crise ci ... [more ▼]

1. Introduction Le projet FRISK (Federal Risk Inventory, Survey and Knowledge building) est une recherche commanditée par le Centre Gouvernemental de Coordination et de Crise (CGCCR) ou centre de crise ci-après. Cette recherche s’inscrit dans une démarche constructive et prospective. Ses objectifs sont multiples et ambitieux : - établir une méthodologie permettant de reproduire la démarche ; - inventorier de manière exhaustive les dangers et risques auxquels la société actuelle est exposée ; - évaluer la fréquence de ces menaces ; - ainsi que leurs conséquences et impacts sur la population belge ; - classer (regrouper en famille et donner une priorité) aux risques ; - consulter les membres et les partenaires du CGCCR pour connaître leur évaluation ; - analyser les différentes approches ; - prendre en compte la perception de la population ; - s’inspirer d’études et de travaux similaires, belges et internationaux ; - inscrire cette étude dans le cadre de la définition d’une situation de crise conformément aux AR du 18 avril 1988 (création du CGCCR) et du 31 janvier 2003 (définition phase 4). [less ▲]

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See detailAperçu de la loi du 2 août 2002 concernant la lutte contre le retard de paiement dans les transactions commerciales
Decharneux, Joëlle ULg

in Actualité législative en droit immobilier (2001-2003) (2004)

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See detailSimenon et la “crise” du roman
Denis, Benoît ULg

in Traces. Travaux du Centre d'Études Georges Simenon (2004), (15), 95-106

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See detailValidation of OSIRIS, a prescreening tool for the identification of women with an increased risk of osteoporosis.
REGINSTER, Jean-Yves ULg; Ben Sedrine, Wafa ULg; Viethel, P. et al

in Gynecological Endocrinology : The Official Journal of the International Society of Gynecological Endocrinology (2004), 18(1), 3-8

According to the recent recommendations of the European Community and the World Health Organization, identification of risk factors for fracture or low bone mineral density (BMD) should help health ... [more ▼]

According to the recent recommendations of the European Community and the World Health Organization, identification of risk factors for fracture or low bone mineral density (BMD) should help health professionals to make a better use of bone densitometry. This includes helping patients to modify their behaviour and act on modifiable risk factors (correction of low calcium intake and vitamin D deficiencies, etc.) and also to provide evidence-based guidance for starting a treatment when necessary. In this context, we previously developed a clinical scoring index, OSIRIS (OSteoporosis Index of RISk), for classifying women into three categories of risk of osteoporosis. In order to evaluate the discriminatory performance of OSIRIS, we performed the present prospective study in a sample of 889 postmenopausal women from France. The osteoporosis risk depends on the OSIRIS category. Thus, 62% of women in the 'high-risk' category (OSIRIS < or = -3) were osteoporotic, compared to 34% of women in the 'intermediate-risk' category (OSIRIS ranged between -3 and +1) and only 16.8% of women in the 'low-risk' category (score OSIRIS > 1). These results might contribute to the development of more efficient screening strategies for osteoporosis. The patients in the low-risk category do not require immediate BMD testing; women with 'intermediate risk' have to be carefully followed by their doctor with BMD testing decided on a case-by-case basis; for those within the high-risk category, treatment may be initiated immediately and BMD testing performed either to assess the efficacy of the treatment or to increase the long-term compliance of the patient. In conclusion, for clinical practice, a user-friendly tool has been developed. This tool, called OSIRIS, as far as a simple rule allows, identifies the level of osteoporosis risk in women. [less ▲]

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See detailHotspots, complementarity or representativeness? Designing optimal small-scale reserves for biodiversity conservation
Kati, V.; Devillers, P.; Dufrêne, Marc ULg et al

in Biological Conservation (2004), 120(4), 471-480

Reserve networks are a major tool of ecological management aiming at biodiversity conservation. Maximizing the number of species conserved with the minimum land sacrifice is a primary requirement in ... [more ▼]

Reserve networks are a major tool of ecological management aiming at biodiversity conservation. Maximizing the number of species conserved with the minimum land sacrifice is a primary requirement in reserve design. In this study, we examine the efficiency of five different scenarios to conserve: (i) the biodiversity of one target group and (ii) the overall biodiversity of an area. The study was conducted in Dadia Reserve, in northern Greece. Six groups of species were selected to represent its biodiversity: woody plants, orchids, Orthoptera, aquatic and terrestrial herpetofauna, and small terrestrial birds. The scenarios examined represent different conservation approaches to select network sites. For each approach, the starting point was one of the above six groups of species, considered as the target group. In scenario A, which reflects the hotspot approach, the sites richest in species are selected. Scenario B selects the sites most complementary in terms of species richness. The next two scenarios use the principle of environmental representativeness, expressed in terms of habitat (scenario C) or vegetation (scenario D). Under scenario E, sites forming the network are selected at random. The rank of scenarios in terms of preserving the species of the target group was always B>A>C>D>E, irrespective of the group considered as target group. Their rank, when preservation of the total biodiversity was the issue, was B, A>C, D>E. © 2004 Elsevier Ltd. All rights reserved. [less ▲]

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