References of "2004"
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See detailL'octréotide LP dans le traitement des ophtalmopathies basedowiennes incipiens : Evaluation prospective VS placebo
Wemeau, J. L.; Caron, P.; Rohmer, V. et al

in XXIème Congrès de la Société Française d'Endocrinologie - Abstract book (2004)

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See detailQuality characteristics and oxidative stability of date seed oil during storage
Besbes, Souhail; Blecker, Christophe ULg; Deroanne, Claude et al

in Food Science & Technology International (2004), 10(5), 333-338

Studies were conducted on some quality characteristics of date seed oil from two date palm cultivars (Phoenix dactylifera L.): Deglet Nour and Allig. The following values were obtained for Deglet Nour and ... [more ▼]

Studies were conducted on some quality characteristics of date seed oil from two date palm cultivars (Phoenix dactylifera L.): Deglet Nour and Allig. The following values were obtained for Deglet Nour and Allig cultivars respectively: unsaponifiable matter 8.92-7.76%, iodine value 45.49-44.08, total phenols 520.81-220.32 mug/g oil, chlorophylls 0.86-0.58 mug/g oil, viscosity 18.50-20.50 mPa.s, refractive index 1.457-1.462, acidity 1.06-2.10mg KOH/g oil and peroxide index 16.00-25.00 meq O-2/100g oil. Lipid fractionation of date seed oil yielded 98.30-97.30% neutral lipids, 97.26-96.90% triglycerides, 0.25-0.18% phospholipids and 0.36-0.31% sterols. Gas-liquid chromatography revealed that the major unsaturated fatty acid was oleic acid (39.17-42.13%) while the main saturated fatty acid was lauric acid (24.34-22.56%). Date seed oil showed high medium molecular weight triglycerides (C32-C42, about 27%). Extinction coefficients at 232 nm and 270 nm increased slightly during 40 days in oven (60degreesC) showing that date seed oil could be easily stored. The production of oil from date seeds provides the use of a renewable resource, and at the same time adding value to agricultural products. [less ▲]

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See detailChronique de la 58ème Session de la Société Internationale Fernand de Visscher au Brésil (20-25 Septembre 2004)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2004), LI

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See detailGenetic diversity of Lima bean in relation with phytogeography in the New World
Baudoin, Jean-Pierre ULg

in Annals of Arid Zone (2004), 43(3 & 4), 355-376

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See detailChapter 3, The Integument : Morphology and Biochemistry
Compère, Philippe ULg; Jeuniaux, Charles ULg; Goffinet, Gerhard ULg

in Forest, J.; von Vaupel Klein, J. C.; Schram, F. R. (Eds.) The Crustacea revised and updated from the Traité de Zoologie Vol 1 (2004)

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See detailEffect of ADAMTS-2, a metalloproteinase containing a disintegrin domain and thrombospondin type I repeats, during angiogenesis in vitro and in vivo
Dubail, Johanne ULg; Kesteloot, Frédéric ULg; Motte, Patrick ULg et al

in Angiogenesis (2004), 7(2), 172

Formation of new blood vessels (angiogenesis) is a key step during the development of various pathologies, including cancer. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They ... [more ▼]

Formation of new blood vessels (angiogenesis) is a key step during the development of various pathologies, including cancer. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They further contain specific domains, such as the ‘‘Thrombospondin type I’’ (TSP1) repeats, that are able to strongly repress angiogenesis, as described for thrombospondin-1 and -2, and for ADAMTS-1 and -8. The primary function of ADAMTS-2 is to process collagen type I, II and III precursors into mature molecules by excising the aminopropeptide. We further hypothesized that it could modulate angiogenesis through its TSP1 repeats. This hypothesis was investigated using different in vitro experimental models of angiogenesis. Recombinant ADAMTS-2 induced morphological changes in human umbilical vein endothelial cells (HUVEC) and human microvessel endothelial cells (HMEC), and significantly reduced their proliferation, attachment and spreading. Similar effects were observed when using inactive ADAMTS-2 mutated at the Zn2+-binding catalytic site. ADAMTS-2 did not alter the initial steps of formation of capillary-like structures by HUVEC in vitro. However, these structures appeared much less stable and were more rapidly disrupted in presence of ADAMTS-2 than in control conditions. ADAMTS-2 was also tested in an ex vivo angiogenesis model using aortic rings from rats and mice, wild type or KO for ADAMTS-2. Outgrowth of capillaries was slightly increased from aortas of ADAMTS-2 KO mice (TS2-/-) as compared to aortas from control animals (TS2+/+), while addition of full size recombinant ADAMTS-2 reduced the formation of capillary structures from rat aortas, suggesting its anti-angiogenic activity. Choroidal neovascularization induced in TS2+/+ or TS2-/- mice by LASER burns was used as in vivo model to confirm the in vitro and ex vivo results. Several genes involved in the healing and angiogenesis processes (fibrillar collagens, VEGF, TGF-beta and CTGF) were not differently regulated in TS2+/+ and TS2-/- mice at 5 days. [less ▲]

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See detailCervical artery dissection: An atypical presentation with Ehlers-Danlos-like collagen pathology?
Ulbricht, D.; Diederich, N. J.; Hermanns-Lê, Trinh ULg et al

in Neurology (2004), 63(9), 1708-10

The authors took skin biopsies of the macroscopically normal skin of seven consecutive patients with spontaneous cervical artery dissection (SCAD). Histologically, alterations of the collagen and elastic ... [more ▼]

The authors took skin biopsies of the macroscopically normal skin of seven consecutive patients with spontaneous cervical artery dissection (SCAD). Histologically, alterations of the collagen and elastic fiber networks were found in six patients. In five, the histologic, immunohistochemical, and ultrastructural changes were similar to those usually found in Ehlers-Danlos syndrome (EDS). This suggests that SCAD is frequently associated with the dermal alterations seen in EDS. [less ▲]

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See detailRole of lipopeptides produced by Bacillus subtilis GA1 in the reduction of grey mould disease caused by Botrytis cinerea on apple
Toure, Y.; Ongena, MARC ULg; Jacques, Philippe ULg et al

in Journal of Applied Microbiology (2004), 96(5), 1151-1160

AIM: Test of Bacillus subtilis strain GA1 for its potential to control grey mould disease of apple caused by Botrytis cinerea. METHODS AND RESULTS: GA1 was first tested for its ability to antagonize in ... [more ▼]

AIM: Test of Bacillus subtilis strain GA1 for its potential to control grey mould disease of apple caused by Botrytis cinerea. METHODS AND RESULTS: GA1 was first tested for its ability to antagonize in vitro the growth of a wide variety of plant pathogenic fungi responsible for diseases of economical importance. The potential of strain GA1 to reduce post-harvest infection caused by B. cinerea was tested on apples by treating artificially wounded fruits with endospore suspensions. Strain GA1 was very effective at reducing disease incidence during the first 5 days following pathogen inoculation and a 80% protection level was maintained over the next 10 days. Treatment of fruits with an extract of GA1 culture supernatant also exerted a strong preventive effect on the development of grey mould. Further analysis of this extract revealed that strain GA1 produces a wide variety of antifungal lipopeptide isomers from the iturin, fengycin and surfactin families. A strong evidence for the involvement of such compounds in disease reduction arose from the recovery of fengycins from protected fruit sites colonized by bacterial cells. CONCLUSIONS: The results presented here demonstrate that, despite unfavourable pH, B. subtilis endospores inoculated on apple pulp can readily germinate allowing significant cell populations to establish and efficient in vivo synthesis of lipopeptides which could be related to grey mould reduction. SIGNIFICANCE AND IMPACT OF THE STUDY: This work enables for the first time to correlate the strong protective effect of a particular B. subtilis strain against grey mould with in situ production of fengycins in infected sites of apple fruits. [less ▲]

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See detailSan Martín devant l'histoire et la mémoire
Raxhon, Philippe ULg

in Raxhon, Philippe; Joset, Jacques (Eds.) Correspondance et autres écrits du Libertador José de San Martín (2004)

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See detailPET in lung cancer
Rigo, Pierre ULg; Hustinx, Roland ULg; Bury, Thierry ULg

in Bailey, D. L.; Townsend, D. W.; Valk, P. E. (Eds.) et al Positron emission tomography. Principles and practice (2004)

Positron Emission Tomography - basic science and clinical practice thoroughly explains the principles, clinical applications and economic aspects of PET today. Chapters go into detail on PET applications ... [more ▼]

Positron Emission Tomography - basic science and clinical practice thoroughly explains the principles, clinical applications and economic aspects of PET today. Chapters go into detail on PET applications in oncology, the central nervous system, cardio-respiratory systems, infectious diseases and pediatrics. Discussions are also found on technology design and evaluation, PET in drug discovery and development, and in imaging gene expression and therapy. [less ▲]

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See detailOrigine biogénétique des triterpènes pentacycliques présents dans la sécrétion défensive de Platyphora Kollari (Chrysomelidae)
Ghostin, Jean; Laurent, Pascal ULg; Daloze, Désiré et al

Poster (2004)

Les chrysomèles sont des insectes phytophages brillamment colores qui, avec plus de 32000 espèces, représentent une des familles (Chrysomelidae) les plus importantes de 1'ordre des coléoptères. Etant ... [more ▼]

Les chrysomèles sont des insectes phytophages brillamment colores qui, avec plus de 32000 espèces, représentent une des familles (Chrysomelidae) les plus importantes de 1'ordre des coléoptères. Etant aposématiques, ils sont facilement repérables par des prédateurs potentiels et ont, au cours de 1'evolution, développé des mécanismes de défense chimique élaborés. La découverte de glycosides triterpéniques basés sur le squelette oléanane (comme par exemple le ligatoside B) dans les secrétions défensives de plusieurs espèces de Doryphorina (Platyphora, Desmogramma et Leptinotarsa) a soulevé le problème de leur origine biogénétique. En effet, il est bien connu que les insectes ne possèdent pas la squalène synthase, une enzyme indispensable à la formation des stéroïdes et des triterpènes pentacycliques. Des lors, une biosynthèse de novo de ce type de dériveé par les chrysomèles est peu probable. Par ailleurs, l’analyse de la plante hôte des chrysomèles a montre que la séquestration des glycosides au départ de cette plante est également exclue. Une troisième possibilité serait que 1'insecte utilise un précurseur provenant de son alimentation pour fabriquer ses substances défensives. Un tel précurseur pourrait être la la b-amyrine identifiée chez différentes plantes hôtes des chrysomèles ou 1'acide oléanolique dont la structure de base se retrouve au niveau des triterpènes défensifs. Enfin l’analyse des plantes hôtes a montré que celles-ci contiennent a la fois de la b-amyrine et de l’a-amyrine dans un rapport 1,76/1. Cependant, aucun glycoside triterpénique basé sur le squelette ursane n'a été isolé jusqu'à présent chez les chrysomèles, ce qui suggère un mécanisme de transport sélectif en faveur de la b-amyrine . Dans le cadre de ce travail, nous présenterons les synthèses d'a-amyrine, de b-amyrine et d'acide oléanolique trideutériés, ainsi que les résultats d'incorporation des deux premiers précurseurs chez Platyphora kollari. [less ▲]

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See detailLes jumeaux et leur séparation : situations pathologiques à l‘adolescence et perspectives thérapeutiques
Malchair, Alain ULg

in Information Psychiatrique (L') (2004), 80(2), 123-129

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See detailCanonical framework for describing suboptimum methods for radar STAP
De Grève, Sébastien; Lapierre, Fabian D.; Verly, Jacques ULg

Conference (2004)

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See detailThe Recovery of Mamlūk Chancery Documents in an Unsuspected Place
Bauden, Frédéric ULg

in Winter, Michael; Levanoni, Amalia (Eds.) The Mamluks in Egyptian and Syrian Politics and Society (2004)

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