References of "2004"
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See detailClés de lecture de Regards de l'Education n° 7 : les indicateurs de l'OCDE
Barthélémy, D.; Baye, Ariane ULg; Blondin, Christiane ULg et al

Report (2004)

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See detailNew approach to vascular injection in fresh cadaver dissection.
Heymans, Olivier Y; Nelissen, Xavier P; Peters, Stephane et al

in Journal of Reconstructive Microsurgery (2004), 20(4), 311-5

Vascular injection techniques for anatomic studies are often complementary. Use of colored gelatinous mixtures with methylene blue provides precious data about descriptive anatomy by the contrast that it ... [more ▼]

Vascular injection techniques for anatomic studies are often complementary. Use of colored gelatinous mixtures with methylene blue provides precious data about descriptive anatomy by the contrast that it produces in the tissues. The introduction of radiopaque medium, such as lead oxide, into the gelatinous mixture can be used as a complement by means of x-ray examination, in order to facilitate and to reduce the time of investigation. Addition of rhodamine B to the radiopaque mixture keeps the advantages of the contrast medium, but also permits further dissection to demonstrate some details shown by prior x-ray examination. This article compares these different injection techniques in the study of the nasal vascular network. Moreover, it depicts a new injection approach that allows the investigation of vascular territories depending on thin caliber arteries by selective reinjection, defining microangiosomes. Each above-cited technique was used in ten facial territories of fresh cadavers. The patterns of the vessels shown by these techniques were identical, with a constant visualization of infra-millimetric arteries. However, selective reinjection was the only method that permitted characterization of the proper vascular territory of the lateral nasal artery. [less ▲]

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See detailHistology and physiology of skin aging
Quatresooz, Pascale ULg

Conference (2004)

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See detailThe Bryophyte Layer In A Calcareous Grassland After A Decade Of Contrasting Mowing Regimes
Vanderpoorten, Alain ULg; Delescaille, Lm.; Jacquemart, Al.

in Biological Conservation (2004), 117(1),

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See detailState of the art and challenges of post-harvest diseases management in apples
Jijakli, Haissam ULg; Lepoivre, Philippe ULg

in Mukerij, K. G. (Ed.) Disease Management of fruit and vegetables (2004)

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See detailThe genus Biernatella Baliński, 1977 (Brachiopoda) from the late Frasnian of Belgium
Mottequin, Bernard ULg

in Bulletin de l'Institut Royal des Sciences Naturelles de Belgique. Sciences de la Terre (2004), 74 (supplément)

The genus Biernatella (Brachiopoda; Athyridida), characterized by the presence of a diplospiralium, is definitely recognized for the first time in the late Frasnian (Lower-Upper Palmatolepis rhenana Zones ... [more ▼]

The genus Biernatella (Brachiopoda; Athyridida), characterized by the presence of a diplospiralium, is definitely recognized for the first time in the late Frasnian (Lower-Upper Palmatolepis rhenana Zones) of the southern flank of the Dinant Synclinorium and of the Philippeville Anticlinorium (southern Belgium). A new species (B. abunda n. sp.) from the Neuville Formation (Dinant Synclinorium) is described. In the Philippeville Anticlinorium, B. abunda n. sp. occurs in the Neuville Formation and probably at the base of the Les Valisettes Formation but specifically unidentified specimens of Biernatella have also been collected near the top of this last formation. [less ▲]

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See detailLa guerre des Awans et des Waroux
Masson, Christophe ULg

Master's dissertation (2004)

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See detailWhich metrics to assess and compare the quality of image fusion products ?
Cornet, Yves ULg; Binard, Marc ULg

in New Strategies for European Remote Sensing (2004)

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See detailS'engager dans la lecture : un investissement au service des compétences
Lafontaine, Dominique ULg

in Actes du 3e congrès des chercheurs en éducation, Bruxelles, 16-17 mars 2004 (2004)

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See detailFamilial isolated pituitary adenomas : epidemiological, clinical and genetic studies
Ciccarelli, A.; Valdes Socin, Hernan Gonzalo ULg; Jaffrain-Rea, M. L. et al

in 12th International Congress of Endocrinology - Abstract book (2004)

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See detailCyclodextrins as a potential carrier in drug nebulization.
Evrard, Brigitte ULg; Bertholet, P.; Guéders, Maud ULg et al

in Journal of Controlled Release (2004), 96(3), 403-10

The inhalation route is widely studied for many drug applications focusing on either local or systemic distributions. One matter of concern is the solubilization of hydrophobic drugs. We have studied the ... [more ▼]

The inhalation route is widely studied for many drug applications focusing on either local or systemic distributions. One matter of concern is the solubilization of hydrophobic drugs. We have studied the feasibility of using different cyclodextrins (CDs) to elaborate pharmaceutical formulations for the inhalation route and tested the short-term toxicity of such formulations administered by inhalation to C57BL/6 mice. We have shown that HP-beta-CD, gamma-CD, as well as RAMEB aqueous solutions can undergo aerosolization and that the resulting droplet-size ranges are compatible with pulmonary deposition. In vivo, we have demonstrated that short-term exposure to inhaled HP-beta-CD, gamma-CD and RAMEB solutions are non-toxic after assessing bronchoalveolar lavage (BAL), lung and kidney histology, bronchial responsiveness to methacholine and blood urea. The only change noted is a slight increase in lymphocyte count in the BAL after HP-beta-CD and gamma-CD inhalation. We conclude that CDs are useful in significantly enhancing the solubility of apolar drugs with a view to inhalation therapy although an increase in lymphocyte counts in the BAL after CDs inhalations needs further investigations. [less ▲]

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See detailUne visite insolite au Parc National Henri Pittier (Vénézuela)
Vermeulen, Cédric ULg; Balsacq, R.

in Parcs & Réserves (2004), 59(3), 24-27

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See detailEpidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study
Brun-Buisson, Christian; Minelli, Cosetta; Bertolini, Guido et al

in Intensive Care Medicine (2004), 30(1), 51-61

Abstract Objectives: To re-examine the epidemiology of acute lung injury (ALI) in European intensive care units (ICUs). Design and setting: A 2-month inception cohort study in 78 ICUs of 10 European ... [more ▼]

Abstract Objectives: To re-examine the epidemiology of acute lung injury (ALI) in European intensive care units (ICUs). Design and setting: A 2-month inception cohort study in 78 ICUs of 10 European countries. Patients: All patients admitted for more than 4 h were screened for ALI and followed up to 2 months. Measurements and main results: Acute lung injury occurred in 463 (7.1%) of 6,522 admissions and 16.1% of all mechanically ventilated patients; 65.4% cases occurred on ICU admission. Among 136 patients initially presenting with “mild ALI” (200< PaO2/FiO2 £300), 74 (55%) evolved to acute respiratory distress syndrome (ARDS) within 3 days. Sixty-two patients (13.4%) remained with mild ALI and 401 had ARDS. The crude ICU and hospital mortalities were 22.6% and 32.7% (p<0.001), and 49.4% and 57.9% (p=0.0005), respectively, for mild ALI and ARDS. ARDS patients initially received a mean tidal volume of 8.3±1.9 ml/kg and a mean PEEP of 7.7±3.6 cmH2O; air leaks occurred in 15.9%. After multivariate analysis, mortality was associated with age (odds ratio (OR) =1.2 per 10 years; 95% confidence interval (CI): 1.05–1.36), immuno-incompetence (OR: 2.88; Cl: 1.57–5.28), the severity scores SAPS II (OR: 1.16 per 10% expected mortality; Cl: 1.02–1.31) and logistic organ dysfunction (OR: 1.25 per point; Cl: 1.13–1.37), a pH less than 7.30 (OR: 1.88; Cl: 1.11–3.18) and early air leak (OR: 3.16; Cl: 1.59–6.28). Conclusions: Acute lung injury was frequent in our sample of European ICUs (7.1%); one third of patients presented with mild ALI, but more than half rapidly evolved to ARDS. While the mortality of ARDS remains high, that of mild ALI is twice as low, confirming the grading of severity between the two forms of the syndrome. [less ▲]

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See detailTroubles nerveux accompagnant les maladies organiques ou métaboliques
Amory, Hélène ULg

in Proceedings of 2ème Journée Toulousaine de Médecine Equine (2004)

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See detailThe evolution of inorganic chlorine above the Jungfraujoch station: an update.
Mahieu, Emmanuel ULg; Duchatelet, Pierre ULg; Zander, Rodolphe ULg et al

in Zerefos, C. S. (Ed.) Proceedings of the 20th Quadrennial Ozone Symposium (2004)

Within the frame of the NDSC, the total vertical column abundances of HCl and ClONO2, by far the two most important inorganic chlorine reservoirs at northern mid-latitudes, have been further monitored ... [more ▼]

Within the frame of the NDSC, the total vertical column abundances of HCl and ClONO2, by far the two most important inorganic chlorine reservoirs at northern mid-latitudes, have been further monitored above the Jungfraujoch station (Swiss Alps, 46.5ºN, 8.0ºE, 3580m a.s.l.), by analyzing infrared solar absorption spectra recorded with very high-resolution Fourier spectrometers. The mean temporal evolution of the sum of their monthly mean abundance time series indicates that the total stratospheric inorganic chlorine loading (Cly) has decreased slowly (-0.7+/-0.3%/yr, 1-sigma) since it peaked in late 1996, at the limit of being statistically significant at the 2-sigma level. Comparison with model calculations and with the evolution of surface total organic chlorine will also be discussed. [less ▲]

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See detailSustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer
Yu, P. W.; Tabuchi, R. S.; Kato, R. M. et al

in Blood (2004), 104(5), 1281-90

X-linked agammaglobulinemia (XLA) is a human immunodeficiency caused by mutations in Bruton tyrosine kinase (Btk) and characterized by an arrest in early B-cell development, near absence of serum ... [more ▼]

X-linked agammaglobulinemia (XLA) is a human immunodeficiency caused by mutations in Bruton tyrosine kinase (Btk) and characterized by an arrest in early B-cell development, near absence of serum immunoglobulin, and recurrent bacteria infections. Using Btk- and Tec-deficient mice (BtkTec-/-) as a model for XLA, we determined if Btk gene therapy could correct this disorder. Bone marrow (BM) from 5-fluorouracil (5FU)-treated BtkTec-/- mice was transduced with a retroviral vector expressing human Btk and transplanted into BtkTec-/- recipients. Mice engrafted with transduced hematopoietic cells exhibited rescue of both primary and peripheral B-lineage development, revocery of peritoneal B1 B cells, and correction of serum immunoglobulin M (IgM) and IgG3 levels. Gene transfer also restored T-independent type II immune responses, and B-cell antigen receptor (BCR) proliferative responses. B-cell progenitors derived from Btk-transduced stem cells exhibited higher levels of Btk expression than non-B cells; and marking studies demonstrated a selective advantage for Btk-transduced B-lineage cells. BM derived from primary recipients also rescued Btk-dependent function in secondary hosts that had received a transplant. Together, these data demonstrate that gene transfer into hematopoietic stem cells can reconstitute Btk-dependent B-cell development and function in vivo, and strongly support the feasibility of pursuing Btk gene transfer for XLA. [less ▲]

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See detailActivity-Stability Relationships in Extremophilic Enzymes
D'Amico, Salvino ULg

Conference (2004)

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