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See detailTime-dependent behaviour of oil reservoir chalk: A multiphase approach
De Gennaro, Vincenzo; Delage, Pierre; Cui, Yu Jun et al

in Soils and Foundations (2003), 43(4),

In the North Sea Ekofisk oilfield, oil is located in a 300 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. After the initial phase of depletion an enhanced oil recovery procedure was carried ... [more ▼]

In the North Sea Ekofisk oilfield, oil is located in a 300 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. After the initial phase of depletion an enhanced oil recovery procedure was carried out by injecting sea water (waterflooding). An unexpected consequence of this waterflooding has been the occurrence of a seafloor subsidence, corresponding up to now to a decrease of the seafloor level of approximately 10 m. It is now well recognised that hydro-mechanical coupling involving multiphase fluid interactions (oil and water) is determinant for the interpretation of the phenomenological aspects associated with the chalk compaction and the related subsidence observed in the North Sea oilfields (Ekofisk reservoir) when water flooded. The subsidence due to waterflooding is interpreted as a collapse phenomenon due to suction decrease, typical of loose and low plasticity unsaturated soils when wetted under load. On the other hand, time-dependent stress-strain behaviour of geomaterials is one of the major concerns in soil mechanics and, in effect, subsidence includes creep effects. A multiphase approach, including creep effects under controlled suction levels, is proposed in this paper; the preliminary results of this study are presented and discussed. Attention will be focused at first on the theoretical approach, supplying the essential elements for the work, and on the interpretation of the experimental results. This will provide secondly the base for formulation and validation of the constitutive law proposed for the description of the time-dependent mechanical behaviour of the chalk. [less ▲]

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See detailNF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells
Bentires-Alj, Mohamed; Barbu, Véronique; Fillet, Marianne ULg et al

in Oncogene (2003), 22

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and ... [more ▼]

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and neoplastic cells often develop multiple mechanisms of drug resistance during tumor progression. We observed that NF-kappaB or P-glycoprotein inhibition in the HCT15 colon cancer cells led to increased apoptotic cell death in response to daunomycin treatment. Interestingly, NF-kappaB inhibition through transfection of a plasmid coding for a mutated IkappaB-alpha inhibitor increased daunomycin cell uptake. Indeed, the inhibition of NF-kappaB reduced mdr1 mRNA and P-glycoprotein expression in HCT15 cells. We identified a consensus NF-kappaB binding site in the first intron of the human mdr1 gene and demonstrated that NF-kappaB complexes could bind with this intronic site. Moreover, NF-kappaB transactivates an mdr1 promoter luciferase construct. Our data thus demonstrate a role for NF-kappaB in the regulation of the mdr1 gene expression in cancer cells and in drug resistance. [less ▲]

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See detailVers une politique de qualité, à quel prix ?
Claustriaux, Jean-Jacques ULg; Cordier, L.; Duquesne, Brigitte ULg et al

Scientific conference (2003)

Description de l'utilisation d'une base de données relative aux achats de produits alimentaires effectués par des ménages.

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See detailComments on Pouillot, R., Gerbier, G. & Gadner, I.A. “TAGS”, a program for the evaluation of test accuracy in the absence of a gold standard
Berkvens, D. L.; Speybroeck, N.; Lesaffre, E. et al

in Preventive Veterinary Medicine (2003), 59

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See detailAndropause and psychopathology: minor symptoms rather than pathological ones.
Delhez, Marie; Hansenne, Michel ULg; Legros, Jean-Jacques ULg

in Psychoneuroendocrinology (2003), 28(7), 863-74

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects ... [more ▼]

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects were 153 men, aged 50-70 years, who participated in a screening of andropause. Total testosterone, FSH, LH and SHBG levels were measured. Depressed mood was assessed with the Carroll Rating Scale, anxiety with the "anxiety-insomnia" dimension of the General Health Questionnaire, and quality of life with the World Health Organisation Quality of Life questionnaire. The results showed that levels of free T decreased with age, whereas FSH and LH increased. Carroll Rating Scale scores were higher among hypogonadal subjects, but the mean score was low and not pathological. A negative correlation was observed between severity of depression as assessed by the Carroll Rating Scale and free T levels. However, subjects with a significant score on this scale did not exhibit different free T levels compared to subjects with a non-significant depressive score. Anxiety and quality of life did not differ between hypogonadal and eugonadal subjects. The present study therefore suggests that andropause is not characterised by specific psychological symptoms, but may be associated with "depressive symptoms" that are not considered as pathological. [less ▲]

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See detailConditions for elasto-plastic strain localization in unsaturated soils
Charlier, Robert ULg; Baltov, A.; Datcheva, Maria et al

in Journal of Theoretical and Applied Mechanics (2003), 33(3), 101-118

The necessary and sufficient conditions for elasto-plastic strain localization initiation in unsaturated soli massifs are proposed. Unsaturated behaviour is described unsing net stress and suction as ... [more ▼]

The necessary and sufficient conditions for elasto-plastic strain localization initiation in unsaturated soli massifs are proposed. Unsaturated behaviour is described unsing net stress and suction as independent stress variables and modifying the basic constitutive surface parameters and hardening rules to consider the role of suction. The process is accepted to be static isothermal. The conception that the localization band initiates due to loss of stability of deformation process is used. In that case, the rates of process measures bifurcate. A special example is given to illustrate the application of the obtained conditions. [less ▲]

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See detailLe lérot: trois études en une enquête
Libois, Roland ULg

Learning material (2003)

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See detailEquity of the European Educational Systems. A set of indicators. Synthesis of the report.
Demeuse, Marc; Baye, Ariane ULg; Straeten, Marie-Hélène et al

Book published by Université de Liège, Service de Pédagogie expérimentale (2003)

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See detailFengycin penetration into a DPPC monlayer: a study using the Langmuir trough technique with the Brewster angle microscopy
Deleu, Magali ULg

in International symposium on surface and colloid chemistry for the life sciences (2003)

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See detailDysregulation of inflammation
Bureau, Fabrice ULg; Lekeux, Pierre ULg

in Hoffman, A.; Robinson, N. E.; Wade, J. F. (Eds.) Proceedings of a Workshop on “Inflammatory Airway Disease: Defining the Syndrome”, Havemeyer Foundation Monograph Series No. 9 (2003)

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See detail"Sum Petri Aegidii" : kanttekeningen bij een recent opgedoken boek uit de bibliotheek van Pieter Gillis (1486-1533)
Adam, Renaud ULg

in De Gulden Passer = Le compas d'or (2003), 81

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See detail"Bauforschnung" et dendrochronologie
Hoffsummer, Patrick ULg

in de Jonge, Krista; Van Baelen, Koen (Eds.) Preparatory Architectural Investigation in the Restoration of Historical Buildings (2003)

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See detailLe bloc officiel et résidentiel: phase 1
Van der Stede, Véronique ULg

in Lebeau, Marc; Suleiman, Antoine (Eds.) Tell Beydar, Five Seasons of Excavations (1995-1999), A Preliminary Report (2003)

 Cet article est consacré au palais mis au jour à Tell Beydar, une cité-état du 3e millénaire av. n. è. localisée dans le nord-est de la Syrie. Le lecteur y trouvera une description détaillée du bâtiment ... [more ▼]

 Cet article est consacré au palais mis au jour à Tell Beydar, une cité-état du 3e millénaire av. n. è. localisée dans le nord-est de la Syrie. Le lecteur y trouvera une description détaillée du bâtiment, une analyse du système de circulation ainsi qu’une évaluation des possibilités d’éclairage de l’édifice et de celles de restitution d’un étage. Il se termine par une analyse fonctionnelle des pièces et replace le bâtiment dans le contexte de l’architecture palatiale du Bronze ancien. [less ▲]

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See detailPion Structure Function and violation of the Momentum Sum Rule
Lansberg, Jean-Philippe ULg; Bissey, F.; Cudell, Jean-René ULg et al

in Blin, A. H.; Hiller, B.; Ruivo, M. C. (Eds.) et al Hadron Physics: Effective Theories of Low Energy QCD N°2 (2003)

We present a method to evaluate the pion structure functions from a box diagram calculation. Pion and constituent quark fields are coupled through the simplest pseudoscalar coupling. The gamma^* pi -> q ... [more ▼]

We present a method to evaluate the pion structure functions from a box diagram calculation. Pion and constituent quark fields are coupled through the simplest pseudoscalar coupling. The gamma^* pi -> q \bar q cross-section is evaluated and related to the structure functions. We then show that the introduction of non-perturbative effects, related to the pion size and preserving gauge invariance, provides us with a straighforward relation with the quark distribution. It is predicted that higher-twist terms become negligible for Q^2 larger than about 2 GeV^2 and that quarks in the pion have a momentum fraction smaller than in the proton. We enlarge the discussion concerning this violation of the momentum sum rule, emphasizing that the sum rule is recovered in the chiral limit and also when the finite size condition is not imposed. [less ▲]

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See detailCassini UVIS and HST STIS Time-Resolved Jupiter Auroral Data Compared to QP Radio Bursts
Pryor, W.; Hospodarsky, G.; Stewart, I. et al

Poster (2003)

The Cassini Ultraviolet Imaging Spectrograph (UVIS) observed Jupiter in a 4-sec integration "high time-resolution mode" on Jan 8, 13-14, and 20-21 in 2001. In this mode Extreme-Ultraviolet and Far ... [more ▼]

The Cassini Ultraviolet Imaging Spectrograph (UVIS) observed Jupiter in a 4-sec integration "high time-resolution mode" on Jan 8, 13-14, and 20-21 in 2001. In this mode Extreme-Ultraviolet and Far-Ultraviolet spectra were obtained with reduced spectral and spatial resolution in order to study rapid variations in H2 band and H Lyman alpha emission. Previous work has shown that the region inside Jupiter's main auroral ovals contains highly variable spots of emission (auroral flares) that persist for typically 1 or 2 minutes. This duration is similar to that in Jupiter's quasi-periodic (QP) radio bursts. We compare UVIS data to simultaneous Galileo Plasma Wave Subsystem (PWS) and Cassini Radio and Plasma Wave Subsystem (RPWS) observations. Jan 8 was an active period for UV variability, that we associate with polar auroral flares. There is a correlation between the radio and UV bursts in this period, suggesting that they are related phenomena. We will also explore coordinated Hubble Space Telescope Imaging Spectrograph (STIS) time-tagged UV images from Dec 14 and Dec 16, 2000, and Jan 13-14, and Jan 20-21, 2001 to study the spatial properties of the auroral flares. The auroral emissions inside the main oval were most prominent in the Dec 14, 2000 HST data. We acknowledge support from the Cassini Project, the Space Telescope Science Institute, and the NASA OSS Minority University Initiative. [less ▲]

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See detailClinicopathological data in equids suffering from ante-hepatic, hepatic and post-hepatic diseases
Amory, Hélène ULg; Perron, MF; Sandersen, Charlotte ULg et al

in Proceedings of the 42th Annual Congress of the British Equine Veterinary Association (BEVA) (2003)

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See detailProgesterone, cortisol and pregnancy-associated glycoprotein concentrations in three aborted cows
Alomar, M.; Sulon, J.; El Amiri, B. et al

in Proceedings of the 8e Journée de rencontre Bioforum (2003)

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See detailLa voie transobturatrice de dedans en dehors: Considérations anatomiques
Bonnet, Pierre ULg; Waltregny, David ULg; de Leval, Jean ULg

in Progrès en Urologie (2003), 13(5)(Suppl.), 22

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See detailRight ventricular diastolic function in acute pulmonary embolism
Morimont, Philippe ULg; segers, P.; Ghuysen, Alexandre ULg et al

Poster (2003)

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