References of "2003"
     in
Bookmark and Share    
Full Text
See detailLa sous-traitance internationale : questions choisies
Wautelet, Patrick ULg

in Commisison droit et vie des affaires (Ed.) La sous-traitance (2003)

In this paper, a general overview is given of the legal problems arising in the context of cross-border subcontracting operations. Particular attention is paid to the difficulties arising out of the fact ... [more ▼]

In this paper, a general overview is given of the legal problems arising in the context of cross-border subcontracting operations. Particular attention is paid to the difficulties arising out of the fact that the sub-contracting agreement is intertwined with the main contracting agreement [less ▲]

Detailed reference viewed: 361 (10 ULg)
Full Text
Peer Reviewed
See detailEpidural hematoma after cervical spine surgery.
Hans, Pol ULg; Delleuze, Pierre Philippe; Born, Jacques Daniel et al

in Journal of Neurosurgical Anesthesiology (2003), 15(3), 282-5

The authors report an acute epidural hematoma after the surgical removal of a cervical C6-C7 disc herniation through an anterolateral approach of the cervical spine. Clinical history consisted of ... [more ▼]

The authors report an acute epidural hematoma after the surgical removal of a cervical C6-C7 disc herniation through an anterolateral approach of the cervical spine. Clinical history consisted of respiratory distress and flaccid tetraplegia that appeared 2.5 hours after surgery. Without any complementary radiologic investigation, the patient was immediately transferred to the operating room for a second look, which was unsuccessful. Magnetic resonance imaging performed after this second surgical procedure showed an anterior cervical hematoma extending from C3 to T3 without significant spinal cord compression. A cervical laminectomy was performed to evacuate the hematoma. The patient was extubated the next morning and discharged from the hospital after 5 days with no residual neurologic deficit. An extensive postoperative investigation revealed no coagulation disorder. [less ▲]

Detailed reference viewed: 52 (1 ULg)
See detailIl quarto musicista
Emmanuel, François; Ricciardi, Stefania ULg

Book published by San Paolo (2003)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailNF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells
Bentires-Alj, Mohamed; Barbu, Véronique; Fillet, Marianne ULg et al

in Oncogene (2003), 22

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and ... [more ▼]

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and neoplastic cells often develop multiple mechanisms of drug resistance during tumor progression. We observed that NF-kappaB or P-glycoprotein inhibition in the HCT15 colon cancer cells led to increased apoptotic cell death in response to daunomycin treatment. Interestingly, NF-kappaB inhibition through transfection of a plasmid coding for a mutated IkappaB-alpha inhibitor increased daunomycin cell uptake. Indeed, the inhibition of NF-kappaB reduced mdr1 mRNA and P-glycoprotein expression in HCT15 cells. We identified a consensus NF-kappaB binding site in the first intron of the human mdr1 gene and demonstrated that NF-kappaB complexes could bind with this intronic site. Moreover, NF-kappaB transactivates an mdr1 promoter luciferase construct. Our data thus demonstrate a role for NF-kappaB in the regulation of the mdr1 gene expression in cancer cells and in drug resistance. [less ▲]

Detailed reference viewed: 84 (9 ULg)
Full Text
See detailLa Zone Villageoise de Chasse de Sia (Ranch de Gibier de Nazinga, Burkina Faso)
Vermeulen, Cédric ULg; Ouédraogo, M.

in Parcs & Réserves (2003), 58(2), 32-44

Detailed reference viewed: 63 (8 ULg)
Full Text
Peer Reviewed
See detailLa varicelle et le zona ou les mystères de la latence d'un virus et de sa réactivation
Rentier, Bernard ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2003), 158(3-4), 169-73174-5

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological ... [more ▼]

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological features of these diseases such as complications of chicken pox, viral latency in sensory ganglia and reactivation as shingles with concurrent and possibly subsequent prolonged pain, are the sequels of the invasion of the peripheral nervous system during primary infection. Prevention is achieved by vaccination with a live attenuated virus strain and therapy calls for specific antiviral agents. In many respects, vzv behaves differently from close relatives. In particular, viral latency in the nervous system is basically different from that of other Herpesviridae. The recent discovery of the expression of some viral regulatory proteins during latency, although it had always been considered that vzv latency was silent, and demonstration that these proteins are immunogenic open new avenues concerning the immune control of vzv reactivation. [less ▲]

Detailed reference viewed: 38 (4 ULg)
Full Text
Peer Reviewed
See detailHow ergodic is the Fragmentation of the Pyridine Cation ? A Maximum Entropy Ananlysis
Gridelet, E.; Locht, Robert ULg; Lorquet, Andrée ULg et al

in Anton, J.; Cederquist, H.; Larsson, M. (Eds.) et al 23rd International Conference on the Photonic, Electronic and Atomic Collisions: Book of Abstracts. (2003)

The experimental KER and the statistical distributions are compared by the Maximum Entropy Method. An Ergodicity Index F(E) is defined to measure the phase space sampling efficiency. This is applied to ... [more ▼]

The experimental KER and the statistical distributions are compared by the Maximum Entropy Method. An Ergodicity Index F(E) is defined to measure the phase space sampling efficiency. This is applied to the KERD of C4H4+ cation produced by the C5H5N+ -> HCN+C4H4+ fragmentation path. In this particular case the F(E) is found to decrease steadily with increasing internal energy. [less ▲]

Detailed reference viewed: 31 (6 ULg)
See detailDes Fleurs de saints à l'odeur de sainteté. L'hagiographie en terres wallonnes,
George, Philippe ULg; Raschevitch, Sonia ULg

in Dumortier, Jean-Louis; George, Philippe (Eds.) Regards sur le XVIIe siècle. Feuillets de la Cathédrale de Liège. (2003)

Detailed reference viewed: 11 (2 ULg)
Full Text
Peer Reviewed
See detailDistinct T cell subsets and cytokine production in cultures derived from transformation zone and squamous intraepithelial lesion biopsies of the uterine cervix.
Jacobs, Nathalie ULg; Renard, Isabelle; Al-Saleh, Walid et al

in American Journal of Reproductive Immunology (2003), 49(1), 6-13

PROBLEM: The characterization of lymphocytes issued from squamous intraepithelial lesions (SIL) and from the transformation zone (TZ), where the majority of SIL occur, is important to understand the role ... [more ▼]

PROBLEM: The characterization of lymphocytes issued from squamous intraepithelial lesions (SIL) and from the transformation zone (TZ), where the majority of SIL occur, is important to understand the role of immunity in SIL development. METHOD OF STUDY: We compared lymphocyte populations of the TZ and SIL with those of normal exocervix, using a technique allowing for the isolation of lymphocytes, either from the epithelium or from the underlying stroma of small biopsies. RESULTS: The majority of cells derived from the epithelium of all biopsies were CD8+ T cells. Some SIL-derived cultures were characterized by an increased proportion of activated TCRgammadelta+. The production of the immunosuppressive cytokine IL10 was significantly higher in lymphocyte cultures from the normal TZ in comparison with the exocervix. A decreased percentage of effector T cells was observed in cultures derived from the stroma of normal TZ (TCRgammadelta+) or SIL (CD8+) in comparison with the exocervix. CONCLUSIONS: Our results suggest that a low proportion of effector T cells and IL10 production could contribute to the predisposition of the TZ to the development of SIL and to the progression of SIL to cervical cancer. [less ▲]

Detailed reference viewed: 47 (12 ULg)
Full Text
Peer Reviewed
See detailLes protéines de choc thermique (heat shock proteins). II Les protéines de choc thermique (heat shock proteins). II. Hsp70, biomarqueur, bioprotecteur.
Wirth, Delphine; Gustin, Pascal ULg; Drion, Pierre ULg et al

in Annales de Médecine Vétérinaire (2003), 147(2), 127-144

The exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response, was ... [more ▼]

The exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response, was initially discovered in Drosophila. The genes hsps were among the first eukaryotic genes to be cloned and whose regulation, which involves activation of heat shock factor (HSF), was elucidated. More recently, study of Hsp functions, particularly Hsp70, started. Their protective role, related to their molecular chaperon function, was inferred from experiments showing that Hsp70 expression, induced by a first stress, results in a cellular tolerance to second stress. Better understanding of the heat shock response had led to the development of two search fields on Hsp70 expression : (1) its use as biomarker of cellular stress and (2) the exploitation of its cytoprotective functions against various insults. This review includes historic of the research on the heat shock response, description of regulation mechanism of Hsp70 expression, and the interesting perspectives allocated to Hsp70 as biomarker and therapeutic tool. ----------- L’exposition de tout organisme à des températures élevées induit l'expression cellulaire rapide et transitoire de protéines spécifiques, les protéines de choc thermique (Hsps pour " heat shock proteins "). Cette réponse des cellules au choc thermique ou " heat shock response " a été initialement découverte chez la drosophile. Les gènes hsps furent parmi les premiers gènes eucaryotes à être clonés et utilisés comme paradigme dans l'étude des mécanismes de régulation transcriptionnelle faisant intervenir l'activation d'un ou plusieurs " heat shock factors" (HSFs). C'est plus récemment que l'étude des fonctions des Hsps, particulièrement Hsp70, a débuté. Le rôle protecteur de celle-ci, lié à sa fonction de " chaperon " protéique, a été déduit d'expériences montrant que l'induction de l'expression de Hsp70 lors d'un stress était associée au développement d'une tolérance cellulaire vis-à-vis d'un stress ultérieur. En plus d'un intérêt fondamental pour la compréhension de la "réponse au choc thermique", deux axes de recherche appliquée se sont développés visant à investiguer la possibilité d'utiliser l'expression de Hsp70 comme biomarqueur de souffrance cellulaire d'une part et, d'autre part, d'exploiter ses fonctions comme moyen de protection des cellules contre divers types d'agressions. Cette revue décrit l'historique des découvertes sur la " réponse au choc thermique ", le mécanisme régulant l'expression de Hsp70 ainsi que les perspectives intéressantes s'ouvrant à l'utilisation de l'expression de Hsp70 en tant que biomarqueur et outil thérapeutique. [less ▲]

Detailed reference viewed: 141 (11 ULg)
Full Text
Peer Reviewed
See detailEffet de la durée d’application d’un stimulus gravitationnel sur la formation de bois de tension et de bois opposé dans de jeunes pousses de peuplier (Populus euramericana cv ‘Ghoy’)
Jourez, Benoît ULg; Avella-Shaw, Thomas

in Annals of Forest Science : a Multidisciplinary and International Journal (2003), 60

De jeunes pousses de Peuplier Ghoy ont été maintenues artificiellement inclinées pendant des durées croissantes, afin d’induire la formation de tissus de bois de tension et de bois opposé en réaction au ... [more ▼]

De jeunes pousses de Peuplier Ghoy ont été maintenues artificiellement inclinées pendant des durées croissantes, afin d’induire la formation de tissus de bois de tension et de bois opposé en réaction au stimulus gravitationnel. Il apparaît que ces pousses sont susceptibles de percevoir et de réagir à un stimulus extrêmement bref à l’échelle d’une période de végétation. Après un temps de présentation de 6 heures, l’ensemble des pousses ont formé un arc de bois opposé. Toutefois, sur la face supérieure, un temps compris entre 24 et 48 heures est nécessaire pour qu’elles perçoivent la modification de leur état d’équilibre et se mettent à former du bois de tension. Après un temps de latence de 48 heures, la formation de fibres gélatineuses est déjà observée sur la face supérieure des tiges. L’augmentation de la durée du stimulus a des répercussions sur le nombre de fibres gélatineuses et sur l’angle d’ouverture de l’arc de bois de tension. Sur la face inférieure, les fibres de bois opposé se forment à un rythme moins soutenu, conduisant à une excentricité de la moelle dans la section de la tige. Le redressement des pousses est effectif après une durée de stimulus comprise entre 4 et 8 jours. [less ▲]

Detailed reference viewed: 23 (5 ULg)
Full Text
Peer Reviewed
See detailMarine mammals from Northeast Atlantic: relationship between their trophic status as determined by delta C-13 and delta N-15 measurements and their trace metal concentrations
Das, Krishna ULg; Beans, Cristina; Holsbeek, Ludo et al

in Marine Environmental Research (2003), 56(3),

The relationship between trophic position through delta(13)C and delta(15)N and trace metal concentrations (Zn, Cd, Cu and Hg) was investigated in the tissues of six marine mammal species from the ... [more ▼]

The relationship between trophic position through delta(13)C and delta(15)N and trace metal concentrations (Zn, Cd, Cu and Hg) was investigated in the tissues of six marine mammal species from the Northeast Atlantic: striped dolphin Stenella coeruleoalba, common dolphin, Delphinus delphis. Atlantic white-sided dolphin Lagenorhynchus acutus, harbour porpoise Phocoena phocoena, white beaked-dolphin Lagenorhynchus albirostris, grey seal Halichoerus grypus stranded on French Channel and Irish coasts. White-beaked dolphins, harbour porpoises, white-sided dolphins, common and striped dolphins display the same relative and decreasing trophic position, as measured by delta(15)N values, along both the Irish and French channel coasts, reflecting conservative trophic habits between these two places. Hepatic and renal Cd concentrations were significantly correlated to muscle delta(13)C and delta(15)N values while Hg, Zn and Cu did not. These results suggest that Cd accumulation is partly linked to the diet while other factors Such as age or body condition might explain Hg, Zn or Cu variability in marine mammals. Combined stable isotope and trace metal analyses appear to be useful tools for the study of marine mammal ecology. (C) 2003 Elsevier Science Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 108 (15 ULg)
Full Text
See detailde Montpellier d'Annevoie Gérard
Richelle, Marc ULg

in Nouvelle biographie nationale. Vol. 7 (2003)

Detailed reference viewed: 17 (4 ULg)
Full Text
See detailAnalyse sensorielle : principes de base.
Blecker, Christophe ULg

in Cours d'analyse sensorielle du beurre et du lait en poudre. (2003)

Detailed reference viewed: 43 (5 ULg)
Full Text
See detailCloches et plaies des pieds.
Crosset, A.; Uhoda, Emmanuelle ULg; Pierard, Gérald ULg

in Pharma-Sphère (2003), 78

Detailed reference viewed: 22 (0 ULg)