References of "2003"
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See detailA propos de la lutte contre le retard de paiement dans les transactions commerciales
Biquet, Christine ULg

in Delvaux, P.-H.; De Rode, H.; Dubuisson, B. (Eds.) et al Mélanges offerts à Marcel Fontaine (2003)

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See detailLe cri du public. Culture populaire, presse et chanson dialectale au pays de Liège (XVIII et XIXe siècles)
Droixhe, Daniel ULg

Book published by Le Cri / ARLLFB (2003)

Que peuvent nous apprendre les prédictions de l'Almanach de Mathieu Laensbergh en matière d'éveil aux idées de Lumières, au XVIIIe siècle? Quel changement de mentalité à l'égard des pratiques magico ... [more ▼]

Que peuvent nous apprendre les prédictions de l'Almanach de Mathieu Laensbergh en matière d'éveil aux idées de Lumières, au XVIIIe siècle? Quel changement de mentalité à l'égard des pratiques magico-religieuses laissent entrevoir les commentaires du livret de pèlerinage à Saint-Hubert en Ardenne? C'est à de telles questions que tâchent de répondre les essais contenus dans le présent ouvrage, à partir d'une documentation associant littérature « populaire », journaux, catalogues de libraires, chansons, etc. La communication orale y trouve une place importante, notamment quand elle se fait dialectale. La diffusion de valeurs et d'interrogations communes s'opère aussi par le théâtre, où drames sérieux, vaudevilles et opéras-comiques — nous sommes au pays de Grétry — composent un véritable «paysage culturel» moyen. On verra ainsi comment le Laensbergh ou les mémoires rédigés à l'occasion de procès opposant des communautés rurales aux autorités manifestent le progrès du rationalisme critique, à travers un lexique où le bourgeois sensible côtoie l'aristocrate éclairé. De leur côté, les livrets de pèlerinage offrent une mutation du regard sur la «neuvaine» contre la rage, la protection sacrée cédant la place à la conception du contrat marchand et à l'hygiénisme. La réflexion sur l'«amélioration de l'espèce humaine», avec les questions de l'eugénisme, de l'alimentation des enfants et de la vaccination, entrent dans le débat qu'entretiennent le Journal encyclopédique et le Giornale enciclopedico di Liegi. Comment s'étonner de la vigueur avec laquelle les classes populaires verviétoises vont combattre l'ancien régime dans les années qui précèdent sa chute? Une figure d'exception domine intellectuellement et pratiquement l'événement : Nicolas Bassenge. La chanson «patriotique» donne la mesure de son charisme et de l'évolution que connaît celui-ci, quand se développera l'aspiration à une société pacifiée. Une même exigence de conciliation et de pragmatisme s'observe dans le traitement accordé au wallon sous un régime français moins jacobin qu'on ne l'a parfois dit. Y a-t-il continuité ou rupture entre le catalogue de la lecture à la fin du XVIIIe siècle et celui de l'époque romantique? Quelles nouveautés foncières se font jour, à côté d'une tradition persistante du livre «utile» visant désormais l'entrepreneur balzacien? Quelle réception pour un romantisme souvent jugé «dégoûtant»? Avec Georges Sand et les Vésuviennes de 1848, la revendication féministe fera irruption sur la scène locale, tandis qu'alterneront dans la chanson de conscrit complaintes de la fille-mère et gaietés de l'escadron, émaillées de quelques protestations contre l'armée, la guerre et la société d'argent qui les régit. [less ▲]

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See detailHet vrij verkeer van beslissingen binnen de Europese Unie : toepassing op het arbeidsrechtelijk contentieux
Wautelet, Patrick ULg

in de Leval, Georges (Ed.) Espace judiciaire et social européen (2003)

In this paper, written with Prof. Marta Pertegás Sender, we give an overview of the achievements made within the EU in securing the mutual recognition and enforcement of court decisions issued in ... [more ▼]

In this paper, written with Prof. Marta Pertegás Sender, we give an overview of the achievements made within the EU in securing the mutual recognition and enforcement of court decisions issued in employment disputes. Particular attention is given to the special regime of employment disputes under the 1968 Brussels Convention and the Regulation 44/2001. [less ▲]

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See detailSymétries du Monde
Jaminon, Martine ULg; De Meur, Gisèle; Gottcheiner, Alain et al

Learning material (2003)

plaquette de l'exposition " Symétries du monde" présentée à la Maison de la Science

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See detailLa varicelle et le zona ou les mystères de la latence d'un virus et de sa réactivation
Rentier, Bernard ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2003), 158(3-4), 169-73174-5

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological ... [more ▼]

Varicella-zoster virus is a Herpesvirus responsible for three distinct clinical features: chicken pox (varicella), shingles (herpes zoster) and post-zosterian pain (post-herpetic neuralgia). Neurological features of these diseases such as complications of chicken pox, viral latency in sensory ganglia and reactivation as shingles with concurrent and possibly subsequent prolonged pain, are the sequels of the invasion of the peripheral nervous system during primary infection. Prevention is achieved by vaccination with a live attenuated virus strain and therapy calls for specific antiviral agents. In many respects, vzv behaves differently from close relatives. In particular, viral latency in the nervous system is basically different from that of other Herpesviridae. The recent discovery of the expression of some viral regulatory proteins during latency, although it had always been considered that vzv latency was silent, and demonstration that these proteins are immunogenic open new avenues concerning the immune control of vzv reactivation. [less ▲]

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See detailL'éloge de la folie en hôpital de jour: présent du passé et perspectives
Triffaux, Jean-Marc ULg

in Revue des Hôpitaux de Jour Psychiatriques et des Thérapies Institutionnelles (2003)

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See detailEffect of rival males on the courtship of paedomorphic and metamorphic Triturus alpestris (Amphibia : Salamandridae)
Denoël, Mathieu ULg

in Copeia (2003), 2003(3), 618-623

Current theories on the alternative mating tactics suppose that individuals may opt for particular behavioral patterns depending of their morphological status. Facultative paedomorphosis in newts and ... [more ▼]

Current theories on the alternative mating tactics suppose that individuals may opt for particular behavioral patterns depending of their morphological status. Facultative paedomorphosis in newts and salamanders is a suitable process to explore this question because it implies the coexistence of two different morphological morphs differing by the presence of gills and epigamic traits. The aim of this study was to find out whether paedomorphs and metamorphs use similar tactics to attract mates in the presence of a rival and whether there are differences in sexual activity and success between alternative morphs. Sexual interactions in triadic encounters were staged and analyzed in a standardized experimental design. The two kinds of males did not differ in terms of sexual activity, spermatophore deposition or female responsiveness. Both rival paedomorphic and metamorphic males exhibited sexual interference, but in most encounters, intruders just disturbed the courting pair. Sperm transfer success was lower in triadic encounters than in dyadic encounters. These results illustrate that intermorph breeding also occurs in the presence of competitors but that the success rate of the newts is considerably decreased in such competitive situations. Moreover, newts do not use alternative reproductive tactics depending on their status (i.e., paedomorph or metamorph). [less ▲]

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See detailAndropause and psychopathology: minor symptoms rather than pathological ones.
Delhez, Marie; Hansenne, Michel ULg; Legros, Jean-Jacques ULg

in Psychoneuroendocrinology (2003), 28(7), 863-74

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects ... [more ▼]

This study examined the psychological symptomatology of men diagnosed with andropause and the association between calculated free testosterone (T) and depressed mood, anxiety and quality of life. Subjects were 153 men, aged 50-70 years, who participated in a screening of andropause. Total testosterone, FSH, LH and SHBG levels were measured. Depressed mood was assessed with the Carroll Rating Scale, anxiety with the "anxiety-insomnia" dimension of the General Health Questionnaire, and quality of life with the World Health Organisation Quality of Life questionnaire. The results showed that levels of free T decreased with age, whereas FSH and LH increased. Carroll Rating Scale scores were higher among hypogonadal subjects, but the mean score was low and not pathological. A negative correlation was observed between severity of depression as assessed by the Carroll Rating Scale and free T levels. However, subjects with a significant score on this scale did not exhibit different free T levels compared to subjects with a non-significant depressive score. Anxiety and quality of life did not differ between hypogonadal and eugonadal subjects. The present study therefore suggests that andropause is not characterised by specific psychological symptoms, but may be associated with "depressive symptoms" that are not considered as pathological. [less ▲]

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See detailFrom the germinal cells to the newborn animal: The transmission of genes and life through the generations
Drion, Pierre ULg; Szenci, Otto; Ectors, Fabien ULg et al

in Acta Veterinaria Hungarica (2003), 51(3), 371-384

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most ... [more ▼]

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most spectacular manipulations are cloning and transgenesis. This review focuses on the early appearance of germinal cell precursors and the long-standing fate of gametes in mammals. The evident complexity and long-term programming of events in gametes and early embryos explain part of the difficulties encountered during the development of in vitro and in vivo methods such as multiple Ovulation and embryo transfer (MOET), oestrus synchronisation, ovulation induction, superovulation, in vitro maturation and fertilisation, cryopreservation, transgenesis, nuclear transfer and cloning) and the occurrence of unexpected alterations of development, e.g. embryonic or fetal mortality, large-weight newborn syndrome and other dysregulations ill imprinting or DNA transmission. [less ▲]

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See detailNF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells
Bentires-Alj, Mohamed; Barbu, Véronique; Fillet, Marianne ULg et al

in Oncogene (2003), 22

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and ... [more ▼]

The ubiquitous NF-kappaB transcription factor has been reported to inhibit apoptosis and to induce drug resistance in cancer cells. Drug resistance is the major reason for cancer therapy failure and neoplastic cells often develop multiple mechanisms of drug resistance during tumor progression. We observed that NF-kappaB or P-glycoprotein inhibition in the HCT15 colon cancer cells led to increased apoptotic cell death in response to daunomycin treatment. Interestingly, NF-kappaB inhibition through transfection of a plasmid coding for a mutated IkappaB-alpha inhibitor increased daunomycin cell uptake. Indeed, the inhibition of NF-kappaB reduced mdr1 mRNA and P-glycoprotein expression in HCT15 cells. We identified a consensus NF-kappaB binding site in the first intron of the human mdr1 gene and demonstrated that NF-kappaB complexes could bind with this intronic site. Moreover, NF-kappaB transactivates an mdr1 promoter luciferase construct. Our data thus demonstrate a role for NF-kappaB in the regulation of the mdr1 gene expression in cancer cells and in drug resistance. [less ▲]

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See detailThe inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding.
Damblon, Christian ULg; Jensen, Mikael; Ababou, Abdessamad et al

in Journal of Biological Chemistry (2003), 278(31), 29240-51

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and ... [more ▼]

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and perturbed angular correlation (PAC) spectroscopy of the mode of binding of the R and S enantiomers of thiomandelic acid, focusing on their interaction with the two metal ions in cadmium-substituted Bacillus cereus metallo-beta-lactamase. The 113Cd resonances are specifically assigned to the metals in the two individual sites on the protein by using 113Cd-edited 1H NMR spectra. Each enantiomer of thiomandelate produces large downfield shifts of both 113Cd resonances and changes in the PAC spectra, which indicate that they bind such that the thiol of the inhibitor bridges between the two metals. For R-thiomandelate, this is unambiguously confirmed by the observation of scalar coupling between Halpha of the inhibitor and both cadmium ions. The NMR and PAC spectra reveal that the two chiral forms of the inhibitor differ in the details of their coordination geometry. The complex with R-thiomandelate, but not that with the S-enantiomer, shows evidence in the PAC spectra of a dynamic process in the nanosecond time regime, the possible nature of which is discussed. The thiomandelate complex of the mononuclear enzyme can be detected only at low metal to enzyme stoichiometry; the relative populations of mononuclear and binuclear enzyme as a function of cadmium concentration provide clear evidence for positive cooperativity in metal ion binding in the presence of the inhibitor, in contrast to the negative cooperativity observed in the free enzyme. [less ▲]

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See detailGrowth hormone (GH) secretion in patients with childhood-onset GH deficiency: Retesting after one year of therapy and at final height
Thomas, Muriel; Massa, Guy; Maes, Maes et al

in Hormone Research (2003), 59(1), 7-15

Background. Recent studies have shown that many patients treated with growth hormone (GH) during childhood because of idiopathic GH deficiency (GHD) are no longer GH deficient when retested after ... [more ▼]

Background. Recent studies have shown that many patients treated with growth hormone (GH) during childhood because of idiopathic GH deficiency (GHD) are no longer GH deficient when retested after cessation of GH therapy when final height is achieved. These patients are labelled as transient GHD. We hypothesized that normalization of GH secretion in transient GHD could occur earlier during the course of GH treatment, which could allow earlier cessation of GH treatment. Methods: In a retrospective study, GH secretion was re-evaluated after cessation of GH treatment at final height in 43 patients diagnosed during childhood as idiopathic GHD 10 with multiple pituitary hormonal deficiencies (MPHD) and 33 with isolated GHD ([sGHD]). In a prospective study, GH secretion was re-assessed after interruption of GH treatment given for 1 year in 18 children with idiopathic GHD (2 MPHD, 16 IsGHD). GH secretion was evaluated by glucagon or insulin stimulation tests. Results: In the retrospective study, all the 10 patients with MPHD and 64% of the 33 patients with IsGHD were still deficient at re-evaluation using the paediatric criteria to define GHD (GH peak < 10 ng/ml at provocative test). The proportion of persisting deficiency was greater in patients with complete IsGHD (86%, 12/14 patients) than in patients with partial IsGHD (47%, 9/19 patients). With the criteria proposed in adulthood (GH peak <3 ng/ml), all the 10 patients with MPHD were still considered to be deficient. In contrast, only 15% (5/33 patients) with IsGHD had a maximal GH value < 3 ng/ml (36% of the 14 patients with complete IsGHD and none of the 19 patients with partial IsGHD). In the prospective study, after interruption of GH therapy given for 1 year, the 2 patients with MPHD were still GHD at re-evaluation and they resumed GH treatment. Among the 16 patients with IsGHD, 13 (81%) were still deficient (peak response < 10 ng/ml) after 1 year. Two of the 3 patients in whom GHD was not confirmed at retesting after 1 year GH showed again a deficient response at second retesting. Conclusions: Although many patients diagnosed with IsGHD during childhood have a normalized GH secretory capacity when retested during adulthood, early retesting after interruption of GH treatment given for 1 year during childhood does not enable to determine if GH therapy has to be discontinued before cessation of growth. Copyright (C) 2003 S. Karger AG, Basel. [less ▲]

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See detailThe fate of the adjacent motion segments after lumbar fusion.
Gillet, Philippe ULg

in Journal of Spinal Disorders & Techniques (2003), 16(4), 338-45

Lumbar spine fusion is a commonly performed procedure in various pathologic conditions of the spine. Its role remains debated, and moreover, delayed complications may occur, among which is transitional ... [more ▼]

Lumbar spine fusion is a commonly performed procedure in various pathologic conditions of the spine. Its role remains debated, and moreover, delayed complications may occur, among which is transitional segment alteration leading to recurrence of back pain, gross instability, and neurologic symptoms. Little is known about the long-term prevalence of this complication because of a lack of specific studies. We analyzed the fate of the transitional segments in a homogeneous group of patients operated on during a 14-year period for degenerative conditions of the lumbar spine resistant to conservative treatment. Follow-up ranged from 2 to 15 years. Seventy-five percent of our study group had a minimal 5-year follow-up. In this subgroup, 41% of the patients developed transitional segment alterations, and 20% needed a secondary operation for extension of the fusion. Potential risk factors such as postoperative delay, length of fusion, and spine imbalance were recognized. The frequency of delayed alterations of the adjacent segment and the severity of symptoms related to this complication in this study raise questions about the justification of fusion procedures in degenerative conditions of the spine without threatening instability. Data from the literature confirm the severity of the problem, but many uncertainties remain because of the lack of homogeneous and complete data on both the normal evolution of motion segments of the lumbar spine with age and the fate of the same segments when transformed in transitional segments. Future prospective studies on the subject are needed and must deal with homogeneous groups of patients. More reconstructive surgical procedures need to be developed to lessen the need for fusion procedures. [less ▲]

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See detailSpeed of Sound Measurements of the Third Metacarpal Bone in Young Exercising Thoroughbred Racehorses
Carstanjen, B.; Lepage, O. M.; Hars, O. et al

in BONE (2003), 33

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See detailAltered neuronal excitability in cerebellar granule cells of mice lacking calretinin
Gall, D.; Roussel, C.; Susa, I. et al

in Journal of Neuroscience (2003), 23(28), 9320-9327

Calcium-binding proteins such as calretinin are abundantly expressed in distinctive patterns in the CNS, but their physiological function remains poorly understood. Calretinin is expressed in cerebellar ... [more ▼]

Calcium-binding proteins such as calretinin are abundantly expressed in distinctive patterns in the CNS, but their physiological function remains poorly understood. Calretinin is expressed in cerebellar granule cells, which provide the major excitatory input to Purkinje cells through parallel fibers. Calretinin-deficient mice exhibit dramatic alterations in motor coordination and Purkinje cell firing recorded in vivo through unknown mechanisms. In the present study, we used patch-clamp recording techniques in acute slice preparation to investigate the effect of a null mutation of the calretinin gene on the intrinsic electroresponsiveness of cerebellar granule cells at a mature developmental stage. Calretinin-deficient granule cells exhibit faster action potentials and generate repetitive spike discharge showing an enhanced frequency increase with injected currents. These alterations disappear when 0.15 mm of the exogenous fast-calcium buffer BAPTA is infused in the cytosol to restore the calcium-buffering capacity. A proposed mathematical model demonstrates that the observed alterations of granule cell excitability can be explained by a decreased cytosolic calcium-buffering capacity resulting from the absence of calretinin. This result suggests that calcium-binding proteins modulate intrinsic neuronal excitability and may therefore play a role in information processing in the CNS [less ▲]

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See detailReading for change : performance and engagement across countries : results of PISA 2000
Kirsch, I.; De Jong, J.; Lafontaine, Dominique ULg et al

Book published by OCDE (2003)

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See detailFormation continue en jonglerie
Fischbach, Willi; Cloes, Marc ULg

in Revue de l'Education Physique (2003), 43(4), 114-125

Le premier auteur est étudiant passionné de jonglerie, il a réalisé un mémoire de fin d’études portant sur l’utilisation de la jonglerie en milieu scolaire. Cet article est préparé à partir du contenu de ... [more ▼]

Le premier auteur est étudiant passionné de jonglerie, il a réalisé un mémoire de fin d’études portant sur l’utilisation de la jonglerie en milieu scolaire. Cet article est préparé à partir du contenu de formations continuées proposées aux maîtres de stage qui collaborent à la formation des étudiants de l’AESS de l’Institut Supérieur d’Education Physique et de Kinésithérapie de l’ULg. [less ▲]

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