References of "2003"
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See detailHygro-thermal application conditions and adhesion
Courard, Luc ULg; Darimont, Anne ULg; Degeimbre, Robert ULg et al

in Seidler, Peter (Ed.) Industrial Floors 03 (2003)

Coatings are designed to protect concrete against environmental aggression. Water is one of the aggressive parameters able to deteriorate the concrete structure. The objectives of this paper are to ... [more ▼]

Coatings are designed to protect concrete against environmental aggression. Water is one of the aggressive parameters able to deteriorate the concrete structure. The objectives of this paper are to present the effects of water (i) during application of coating on the concrete substrate and (ii) pull-off test. Semi-permanent moisty state produced by absorption from the uncoated face, total immersion or diffusion of water from the back face of the substrate are analysed. Water vapour diffusion and influence of hydrophobic treatment are also investigated. A classification based on increasing influence of the tests and application conditions on adhesion is proposed and clearly points out the negative effect of capillary action from the uncoated face. [less ▲]

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See detailAutoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease: A prospective cohort study
Vermeire, S.; Noman, M.; Van Assche, G. et al

in Gastroenterology (2003), 125(1), 32-39

Background & Aims: Infliximab therapy is an effective approach to treating Crohn's disease. Development of antinuclear antibodies has been described in patients treated, but the size of the problem and ... [more ▼]

Background & Aims: Infliximab therapy is an effective approach to treating Crohn's disease. Development of antinuclear antibodies has been described in patients treated, but the size of the problem and the relationship with autoimmunity have not been investigated. We investigated the occurrence of antinuclear antibodies in 125 consecutive Crohn's disease patients and studied the relationship with symptoms of autoimmunity. Methods: Autoantibodies and clinical data were investigated before and 1, 2, and 3 months after infliximab infusion. If antinuclear antibodies were greater than or equal to1:80, further study of double-stranded DNA, single-stranded DNA, histones, and ENA was performed. Results: Cumulative antinuclear antibody incidence at 24 months was 71 of 125 (56.8%). Almost half of these patients developed antinuclear antibodies after the first infusion, and >75% became antinuclear antibody positive after fewer than 3 infusions. So far, only :15 of 71 patients have become seronegative, after a median of 12 months. Of 43 antinuclear antibody-positive patients who were further subtyped, 14 of 43 (32.6%) had double-stranded DNA, 17 (39.5%) had single-stranded DNA, 9 (20.9%) had antihistone, and 0% were ENA positive. Two patients (both antihistone and double-stranded DNA positive) developed drug-induced lupus without major organ damage, and I developed autoimmune hemolytic anemia. Antinuclear antibodies were associated with the female sex (odds ratio, 3.166; 95% confidence interval, 1.167-8.585; P = 0.024) and with papulosquamous or butterfly rash (odds ratio, 10.016; 95% confidence interval, 1.708-58.725; P = 0.011). Conclusions: The cumulative incidence of antinuclear antibodies was 56.8% after 24 months in this cohort of infliximab-treated Crohn's disease patients. Antinuclear antibodies persisted up to I year after the last infusion, and only a few patients became seronegative. Two patients developed drug-induced lupus erythematosus. Antinuclear antibodies were associated with the female sex and skin manifestations. [less ▲]

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See detailAnatomical and histological aspects of the tonsils in sheep
Gabriel, Annick ULg; Cocquyt, G.; Van den Broeck, W.

in Annales de Médecine Vétérinaire (2003), 147(4, AUG-SEP), 251-258

Since the 1st April 2002, the European Union has extended the Transmissible Spongiform Encephalopathy testing in ruminants by including sheep and goats in the survey studies. In small ruminants, presence ... [more ▼]

Since the 1st April 2002, the European Union has extended the Transmissible Spongiform Encephalopathy testing in ruminants by including sheep and goats in the survey studies. In small ruminants, presence of the agent of Bovine Spongiform Encephalopathy was demonstrated in tonsils, so these are considered as specified risk materials. This article gives an overview of the anatomical localisation and histological structure of the tonsils in small ruminants. Anatomically, 6 different tonsils can be distinguished: 3 are located in the oropharyngeal tract (tonsilla palatina, tonsilla lingualis, tonsilla veli palatini), 2 in the nasopharyngeal tract (tonsilla pharyngea and tonsilla tubaria), and one in the laryngopharyngeal tract (tonsilla paraepiglottica). Several tonsils show a cryptic overlying epithelium (cryptic tonsil) whereas other don't (non-cryptic tonsil). Several immunological features of the tonsils are described. [less ▲]

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See detail3D nonrigid registration and multimodality fusion for image-guided neurosurgery
Verly, Jacques ULg; Vigneron, Lara M.; Martin, Christophe et al

Conference (2003)

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See detailMalignant melanoma
Paquet, Philippe ULg; Hustinx, Roland ULg; Rigo, Pierre ULg et al

in Oehr, Peter; Biersack, Hans_jürgen; Coleman, Edward R (Eds.) PET and PET-CT in Oncology (2003)

PET and PET-CT in Oncology describes the principles of positron emission tomography and is a useful resource for incorporating the technique in clinical practice. In a clear and straightforward fashion ... [more ▼]

PET and PET-CT in Oncology describes the principles of positron emission tomography and is a useful resource for incorporating the technique in clinical practice. In a clear and straightforward fashion, this heavily-illustrated text offers instructive information and overviews of the basic principles of PET and PET-CT as well as the routine clinical PET scanning procedures for all important oncological indications. It is designed to serve as a reference work for specialists in nuclear medicine and radiology (including therapy planning) and for oncologists. It also provides student and physicians in other medical specialities with a general introduction to the effective integration of this modern technique into routine clinical diagnostics. Above all, this volume illustrates the importance of PET and PET-CT in comparison with other imaging techniques. [less ▲]

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See detailHistoire de la littérature belge francophone (1830-2000)
Bertrand, Jean-Pierre ULg; Biron, Michel; Denis, Benoît ULg et al

Book published by Fayard (2003)

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See detailOntologie et phénoménologie dans la pensée de Saussure
Badir, Sémir ULg

in Bouquet, Simon (Ed.) Saussure (2003)

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See detailComment je traite ... les troubles de la magnésémie
Guillaume, Thierry; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2003), 58(7-8), 465-467

Because symptoms associated with hypomagnesia are highly aspecific, this ionic abnormality is rarely searched for although it could be present in as much as 20 % of the population. The mode of correction ... [more ▼]

Because symptoms associated with hypomagnesia are highly aspecific, this ionic abnormality is rarely searched for although it could be present in as much as 20 % of the population. The mode of correction (oral or intravenous) depends on the etiology, severity and clinical consequences of hypomagnesemia. Significant hypermagnesemia only occurs in the presence of renal insufficiency and/or acute excess administration, mainly by the intravenous route. If interruption of administration does not suffice, renal dialysis might become necessary to quickly correct the magnesemium serum levels. [less ▲]

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See detailPhosphate mineral occurrences in Lake Baïkal sediments : Paleo-environment or diagenesis record ?
Fagel, Nathalie ULg; Alleman, L. Y.; André, Luc et al

Poster (2003)

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See detailThe thymic insulin-like growth factor axis: Involvement in physiology and disease
Geenen, Vincent ULg

in Hormone & Metabolic Research (2003), 35(11-12, Nov-Dec), 656-663

A repertoire of neuroendocrine-related genes is transcribed in the non-lymphoid compartment of the thymus, transposing the dual physiological role of this organ at the molecular level in T-cell ... [more ▼]

A repertoire of neuroendocrine-related genes is transcribed in the non-lymphoid compartment of the thymus, transposing the dual physiological role of this organ at the molecular level in T-cell development towards the establishment of central T-cell self-tolerance. The "neuroendocrine self" has been defined as a series of antigen sequences processed from precursors predominantly expressed in the thymus and first encountered by differentiating T-lymphocytes in their early life. All the members of the insulin gene family are expressed in the thymus according to a precise hierarchy and cellular topography, whereby IGF-II (epithelium of the subcapsular cortex and medulla) exceeds IGF-I (macrophages), which in turn far exceeds INS (rare subsets of medullary epithelial cells). This hierarchy in the degree of their respective thymic expression explains why IGF-II is more tolerated than IGF-I, and much more so than insulin. Evidence has been found for significant regulatory/tolerogenic properties in the IGF-II B:11-25 sequence after analysis of the cytokine secretion profile in peripheral blood mononuclear cells isolated from ten DQ8+ type 1 diabetic adolescents. In the thymus, IGF ligands and receptors also intervene in the control of T-cell proliferation and differentiation. Here, we also discuss how a disturbance in the intrathymic IGF-mediated signaling could contribute to the pathogenesis of T-cell leukemia. [less ▲]

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See detailFeasibility and reproducibility of off-line tissue Doppler measurement of regional myocardial function during dobutamine stress echocardiography.
Fraser, A. G.; Payne, N.; Madler, C. F. et al

in European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology (2003), 4(1), 43-53

AIMS: Off-line post-processing of colour tissue Doppler from digital loops may allow objective quantification of dobutamine stress echocardiography. We assessed the reproducibility of off-line ... [more ▼]

AIMS: Off-line post-processing of colour tissue Doppler from digital loops may allow objective quantification of dobutamine stress echocardiography. We assessed the reproducibility of off-line measurements of regional myocardial velocities. METHODS AND RESULTS: Nine observers analysed 10 studies, each making 2400 observations. Coefficients of variation in basal segments from apical windows, at rest and maximal stress, were 9-14% and 11-18% for peak systolic velocity, 16-18% and 17-19% for time-to-peak systolic velocity, 9-17% and 18-24% for systolic velocity time integral, and 18-23% and 21-27% for systolic acceleration. Coefficients of variation for diastolic velocities in basal segments at rest were 11-40%. Coefficients of variation for peak systolic velocity were 10-24% at rest and 14-28% at peak in mid segments, and 19-53% and 29-69% in apical segments. From parasternal windows coefficients of variation for peak systolic velocity were 14-16% in basal posterior, and 19-29% in mid-anterior segments. High variability makes measurement unreliable in apical and basal anterior septal segments. The feasibility of obtaining traces was tested in 92 subjects, and >90% in all basal and mid segments apart from the anterior septum. CONCLUSION: Quantification of myocardial functional reserve by off-line analysis of colour tissue Doppler acquired during dobutamine stress is feasible and reproducible in 11 segments of the left ventricle. The most reliable measurements are systolic velocities of longitudinal motion in basal segments. [less ▲]

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See detailHigh-Efficiency Liquid-Liquid Phase Separation Using Internals
Chatterjee, M; Franken, H; Hülswitt, N et al

Conference (2003)

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See detailSpecial issue on properties of concrete and behavior of concrete columns subjected to fire
Franssen, Jean-Marc ULg

in Fire Technology (2003), 39(1), 97

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See detailEspace construit
Frankignoulle, Pierre ULg

in Lask, Tomke (Ed.) Constructions sociales de l'espace. Les territoires de l'anthropologie de la communication. (2003)

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See detailHaplotype sharing refines the location of an imprinted quantitative trait locus with major effect on muscle mass to a 250-kb chromosome segment containing the porcine IGF2 gene
Nezer, C.; Collette, C.; Moreau, L. et al

in Genetics (2003), 165(1), 277-285

We herein describe the fine mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in ... [more ▼]

We herein describe the fine mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in combination with QTL genotyping by marker-assisted segregation analysis. By identifying a haplotype shared by all "Q" chromosomes, we map the QTL to an approximately 250-kb chromosome segment containing INS and IGF2 as the only known paternally expressed genes. This considerably reinforces the candidacy of these genes, justifying their detailed analysis. [less ▲]

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See detailOrganon
Seron, Denis ULg

in Motte, André; Rutten, Christian (Eds.) Philosophie de la forme: Eidos, idea, morphé dans la philosophie grecque des origines à Aristote (2003)

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See detailMesoscale surface distribution of biogeochemical characteristics in the Crozet Basin frontal zones (South Indian Ocean)
Fiala, M.; Delille, Bruno ULg; Dubreuil, C. et al

in Marine Ecology. Progress Series (2003), 249

A mesoscale study was conducted in January and February 1999 in the Crozet Basin frontal zones (43degrees50' to 45degrees20'S, 61degrees00' to 64degrees30'E) within the southernmost and easternmost ... [more ▼]

A mesoscale study was conducted in January and February 1999 in the Crozet Basin frontal zones (43degrees50' to 45degrees20'S, 61degrees00' to 64degrees30'E) within the southernmost and easternmost convergence area of the Antarctic Circumpolar Current (ACC) and the Agulhas Return Current (ARC). Distribution of biogeochemical parameters was strongly linked to the merged Subtropical (STF) and Subantarctic (SAF) Fronts which mark the border between the cold and less saline subantarctic waters and the warm and more saline subtropical waters. This survey took place during a post-bloom period. Chlorophyll a concentrations were low throughout the study area ranging from 0.2 mug l(-1) in the Polar Frontal Zone (PFZ) to 0.4 mug l(-1) in the Subtropical Zone (STZ). Maximum chlorophyll a values (0.8 mug l(-1)) associated with an increase in biogenic silica concentration (from 0.03 to 0.34 muM) and a diatom peak (1.2 x 10(5) cells l(-1)) were encountered in the northeastern part of the STF edge. Despite northwardly decreasing concentrations of nitrates from 14 muM in the PFZ to 6 PM in the STZ, they were not the main factor limiting phytoplankton growth. Low silicic acid (mean = 0.6 muM) could have limited diatom development in the PFZ and the STZ where diatom numbers were low. In STZ waters, where average diatom numbers were highest, various species of Nitzschia and Thalassiothrix were common, but Pseudonitzschia spp. were dominant. Throughout the survey area, pico- and nano-sized cells dominated the phytoplankton assemblage, and their number was the highest in the STZ. Cyanobacteria, only present in subtropical waters >12.5degreesC, were the major component of the picoplankton size-fraction. While dinoflagellate numbers were low in the Subantarctic Zone (SAZ), their abundance and species numbers increased in the STZ, where Oxytoxum laticeps became dominant and several further large-size species of Prorocentrum, Ceratium and Gymnodinium appeared in addition to those at the STF. The distribution of different biogeochemical parameters suggests that the Crozet Basin frontal region is a non-exporting system at the end of summer. During this post-bloom period, biological activity is low and phytoplankton growth severely limited. This is evidenced by the weak dependence of the partial pressure of carbon dioxide (pCO(2)) on biological activity and the importance of the air-sea exchange in maintaining pCO(2) close to saturation. [less ▲]

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See detailBrain ethanol concentrations and ethanol discrimination in rats : effects of dose and time
Quertemont, Etienne ULg; Green, Heather L.; Grant, Kathleen A.

in Psychopharmacology (2003), 168(3), 262-270

Rationale. In drug discrimination procedures, the substitution pattern for ethanol of various receptor ligands is dependent upon ethanol training dose, presumably reflecting functionally different ... [more ▼]

Rationale. In drug discrimination procedures, the substitution pattern for ethanol of various receptor ligands is dependent upon ethanol training dose, presumably reflecting functionally different concentrations of ethanol in the brain. The discriminative stimulus effects of ethanol are also time-dependent, although very few studies have investigated the time course of ethanol discriminations. Objectives. The present study investigated the relationship between brain ethanol concentrations (BrEC), as measured by intracranial microdialysis of the nucleus accumbens, and the time course of ethanol discriminative effects. Methods. Two groups of rats were trained to discriminate either 1.0 or 2.0 g/kg ethanol from water following a 30-min post-ethanol interval. Following training, the time course of the discriminative stimulus was assessed using a series of abbreviated testing trials at 20-min intervals for 5 h after the administration of various ethanol doses (0, 0.5, 1.0 and 2.0 g/kg). The rats were then fitted with microdialysis probes and the time course of BrECs were determined under conditions similar to the behavioral assessments. Results. BrECs were significantly above zero at 4 min post-gavage and attained peak concentrations of 16 mmol/l, 24 mmol/l and 42 mmol/l at 9 min, 16 min and 95 min after IG administration of 0.5, 1.0 and 2.0 g/kg ethanol, respectively. BrECs were similar in ethanol-naive and ethanol-trained rats, indicating a lack of pharmacokinetic tolerance under these discrimination procedures. The discriminative stimulus effects of ethanol were dose- and time-dependent, with a threshold concentration of approximately 12 mmol/l achieved at 5 min after 1.0 g/kg ethanol gavage in rats trained to discriminate 1.0 g/kg ethanol. Acute tolerance to the discriminative stimulus effects of ethanol was evident from BrECs 2-5 h post-ethanol gavage. Conclusions. Ethanol given intragastrically results in a rapid increase in BrEC, independent of ethanol exposure history. The discriminative stimulus effects of ethanol trained at 30 min post-gavage reflect a specific range of BrEC, and depend on the training dose. These data suggest that qualitatively different stimulus effects of ethanol reflect both different ranges of BrEC, as well as within dose acute tolerance to the discriminative stimulus effects. [less ▲]

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