References of "2003"
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See detail12 septembre 1995 : Pierre Mertens est assigné en référé devant le tribunal de grande instance de Paris pour son roman Une paix royale. L’INTELLECTUEL ET SES FABLES
Denis, Benoît ULg

in Bertrand, Jean-Pierre; Biron, Michel; Denis, Benoît (Eds.) et al Histoire de la littérature belge francophone (1830-2000) (2003)

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See detailLong-term effect on plasma, meat and milk selenium and blood glutathion peroxydase of feeding selenium-enriched barley and haylage to Belgian Blue cows, calves and fattened bulls
de Behr, V.; Marche, C.; Coenen, M. et al

in Proceedings of 7th Conference of the European Society of Veterinary and Comparative Nutrition (2003)

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See detailUne recherche-action pour développer les capacités de compréhension de l’écrit en 1re accueil … Premier bilan
Schillings, Patricia ULg; Poncelet, Débora

in Point sur la Recherche en Education (Le) (2003)

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See detailPhysical and textural characteristics of hydrogenated low-erucic acid rapeseed oil and low-erucic acid rapeseed oil blends
Danthine, Sabine ULg; Deroanne, Claude ULg

in Journal of the American Oil Chemists' Society (2003), 80(2), 109-114

Low-erucic acid rapeseed oil (LERO) and hydrogenated low-erucic acid rapeseed oil (HLERO) were blended in binary systems. The blends were then studied for their physical properties such as solid fat ... [more ▼]

Low-erucic acid rapeseed oil (LERO) and hydrogenated low-erucic acid rapeseed oil (HLERO) were blended in binary systems. The blends were then studied for their physical properties such as solid fat content, melting curves by DSC, textural properties, and polymorphism. Phase behavior diagrams were constructed from the DSC and X-ray results, and isosolid diagrams were constructed from the NMR results. The mixture of HLERO and LERO displayed a monotectic behavior for all the storage time at 15degreesC. The aim of this work was to evaluate physical characteristics of binary blends of HLERO and nonhydrogenated LERO in order to use only LERO and hardened LERO in bakery shortenings. The mixture of 60% HLERO and 40% LERO is suitable to use as a plastic shortening, This blend is beta tending upon storage at 15degreesC. It could be used in pie crust applications. [less ▲]

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See detailBisindole alkaloids from Strychnos guianensis are effective antagonists of nicotinic acetylcholine receptors in cultured human TE671 cells
Wins, Pierre; Margineanu, Ilca; Penelle, Jacques et al

in Naunyn-Schmiedeberg's Archives of Pharmacology (2003), 367(3), 253-259

Several mono- and bisindole quaternary alkaloids isolated from the stem bark of Strychnos guianensis have recently been shown to be effective blockers of neuromuscular transmission in mice. In this study ... [more ▼]

Several mono- and bisindole quaternary alkaloids isolated from the stem bark of Strychnos guianensis have recently been shown to be effective blockers of neuromuscular transmission in mice. In this study, we used a human clonal cell line (TE671) expressing muscle-type nicotinic acetylcholine receptors. The agonist carbamylcholine activated a receptor-mediated Rb-86(+) efflux and this activation was antagonized by the indole alkaloids, the most active being bisindole bisquaternary compounds. The most effective antagonist, guiachrysine, had an IC50 around 0.43 muM in the presence of 0.5 mM carbamylcholine, compared to 0.16 muM for d-tubocurarine, the most potent curarizing alkaloid. Guiaflavine and 5',6'-dehydroguiaflavine were slightly less effective. Monoindole compounds were 10 to 100 times less potent than bisindole alkaloids. Kinetic analysis showed that the inhibition of the carbamylcholine-dependent Rb-86(+) efflux by guiaflavine was of mixed competitive and uncompetitive type. The competitive component (K-I = 0.21 muM) is presumably due to binding at the acetylcholine site, while the uncompetitive component (K'(I) = 0.92 muM) may be due to open channel block. [less ▲]

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See detailLes compétences de l’intervenant en organisation
Pichault, François ULg

in Guénette, Alain-Max; Rossi, M.; Sardas, Jean-Claude (Eds.) Compétences et connaissances dans les organisations (2003)

Study of the conditions under which action research may help the client system to evolve

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See detailAstronomes célèbres et astronomes moins connus ... (1) William Herschel
Biémont, Emile ULg

in Galactée (2003), 34

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See detailVirus Varicelle-Zona
Fillet, A. M.; Sadzot-Delvaux, Catherine ULg; Rentier, Bernard ULg

in Huraux, Jean-Marie; Nicolas, Jean-Claude; Agut, Henri (Eds.) et al Virologie médicale (2003)

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See detailPredictive factors in locally advanced rectal cancer treated with preoperative hyperfractionated and accelerated radiotherapy.
Bouzourene, H; Bosman, F; Matter, M et al

in Human Pathology (2003), 34(6), 541-548

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 ... [more ▼]

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 patients with rectal cancer of grades T3 or T4 and any N underwent preoperative radiotherapy followed by surgical resection. Survival curves were estimated according to the Kaplan-Meier method. Correlation of outcome with clinicopathologic variables (pathologic tumor and lymph node staging, histology, radial resection margin [RRM], clearance, vessel involvement, and tumor regression grade [TRG], quantitated in 5 grades) was evaluated using the Cox proportional hazards model. None of the patients achieved a histologically confirmed complete pathologic response, but 79% of the patients showed partial tumor regression (TRG2–4) and 21% did not show any tumor regression (TRG5). Among the tumors, 22% were of a mucinous type. The RRM was free of tumor in 76% of the surgical specimens. The median clearance was 2 mm. Vascular invasion was present in 37 cases (36%). In the univariate analysis, lymph node metastases, absence of tumor regression, positive RRM, and vascular invasion were correlated with adverse overall survival and diseasefree survival; absence of tumor regression, positive RRM, and clearance <2 mm were correlated with local recurrences; and advanced pT stage was correlated only with disease-free survival. However, in the multivariate analysis, only lymph node metastases and RRM were independent prognostic factors for overall survival and disease-free survival, and clearance <2 mm was an independent prognostic factor for local control. Pathologic parameters remain strong determinants of local recurrence and survival in locally advanced rectal cancer, treated preoperatively with hyperfractionated and accelerated radiotherapy. We show that patients with advanced pT, positive lymph nodes, vascular invasion, positive RRM, clearance <2 mm, or absence of tumor regression are known to have poor clinical outcome. HUM PATHOL 34:541-548. © 2003 Elsevier Inc. All rights reserved. Abbreviations: , computed tomography; DFS, disease-free survival; HART, hyperfractionated accelerated radiotherapy; OS, overall survival; RRM, radial resection margin; TRG, tumor regression grade. [less ▲]

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See detailEffet de l'intensité d'un stimulus gravitationnel induit artificiellement sur la croissance et la formation du bois de tension dans de jeunes pousses de peuplier (Populus euramericana cv. Ghoy).
Jourez, Benoit; Vaianopoulos, Céline; Hebert, Jacques ULg

in Annals of Forest Science : a Multidisciplinary and International Journal (2003), 60(8), 789-802

The formation of tension wood tissue is artificially induced by means of a gravitational stimulus obtained by inclining young shoots of poplar at different intensities, from 0 to 30°, during a growing ... [more ▼]

The formation of tension wood tissue is artificially induced by means of a gravitational stimulus obtained by inclining young shoots of poplar at different intensities, from 0 to 30°, during a growing season. At the end of the experiment, it appears that shoot elongation as well as the angle of tension wood arc are not affected by the stimulus intensity. In contrast, the upright reorientation of the axis, the amount of gelatinous fibres, the secondary growth over bark, the cross-section area of the stem and of the secondary xylem, the different rays, the diameter under bark and the pith eccentricity, react quantitatively to the lean intensity. The amount of tension wood is correlated with the upright reorientation, the secondary growth over bark and the radial growth under bark. Tension wood formation and eccentricity react to the gravitational stimulus but they are not causally linked. Finally, it exists a natural equilibrium position, different from the vertical, to which moved shoots try to return via the formation of a tension wood tissue. [less ▲]

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See detailLe cas clinique du mois. Masse médiastinale antérieure chez une patiente acromégale.
Laret, Vinciane ULg; Valdes Socin, Hernan Gonzalo ULg; Betea, Daniela ULg et al

in Revue Médicale de Liège (2003), 58(12), 724-728

The discovery of an anterior asymptomatic mediastinal mass with acromegaly creates a dilemma for the clinician. As acromegaly can be due to a pituitary tumor but also to an ectopic production of GHRH, the ... [more ▼]

The discovery of an anterior asymptomatic mediastinal mass with acromegaly creates a dilemma for the clinician. As acromegaly can be due to a pituitary tumor but also to an ectopic production of GHRH, the first diagnostic step consists of finding the etiology of the disease in order to use adequate treatment. This can be complicated by the fact that acromegaly can be associated with other tumors (for instance in MEN-1 disease and Carney Complex) and because chronic GH hypersecretion can stimulate tumor overgrowth and perhaps tumor formation. We describe the case of a 44-year-old acromegalic woman with an anterior mediastinal mass. We present the different diagnoses and a review of the literature. [less ▲]

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See detailSolution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance.
Melckebeke, Helene Van; Vreuls, Christelle ULg; Gans, Pierre et al

in Journal of Molecular Biology (2003), 333(4), 711-20

beta-Lactamase and penicillin-binding protein PBP2' mediate staphylococcal resistance to beta-lactam antibiotics, which are otherwise highly clinically effective. Two repressors (BlaI and MecI) regulate ... [more ▼]

beta-Lactamase and penicillin-binding protein PBP2' mediate staphylococcal resistance to beta-lactam antibiotics, which are otherwise highly clinically effective. Two repressors (BlaI and MecI) regulate expression of these inducible proteins. Here, we present the first solution structure of the 82 amino acid residue DNA-binding domain of Bacillus licheniformis BlaI which is very similar in primary sequence to the medically significant Staphyloccocal BlaI and MecI proteins. This structure is composed of a compact core of three alpha-helices and a three-stranded beta-sheet typical of the winged helix protein (WHP) family. The protein/DNA complex was studied by NMR chemical shift comparison between the free and complexed forms of BlaI. Residues involved in DNA interaction were identified and a WHP canonical model of interaction with the operators is proposed. In this model, specific contacts occur between the base-pairs of the TACA motif and conserved amino acid residues of the repressor helix H3. These results help toward understanding the repression and induction mechanism of the genes coding for beta-lactamase and PBP2'. [less ▲]

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See detailTransmission of chronic myeloid leukemia through peripheral-blood stem-cell transplantation.
Baron, Frédéric ULg; Dresse, Marie-Françoise; Beguin, Yves ULg

in New England Journal of Medicine [=NEJM] (2003), 349(9), 913-4

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See detailProlactin Suppresses Glucocorticoid-Induced Thymocyte Apoptosis in Vivo
Krishnan, Nithya; Thellin, Olivier ULg; Buckley, Donna J. et al

in Endocrinology (2003), 144(5), 2102-2110

The hypothesis that prolactin (PRL) functions as an immunomodulator was based on studies showing lymphocyte PRL receptors, and its effects on growth, differentiation, and apoptosis in lymphoid cells ... [more ▼]

The hypothesis that prolactin (PRL) functions as an immunomodulator was based on studies showing lymphocyte PRL receptors, and its effects on growth, differentiation, and apoptosis in lymphoid cells. However, studies of PRL (PRL-/-) and PRL receptor knockout mice indicated that PRL was not required for immune system development or function under basal conditions. Because PRL maintains survival in glucocorticoid (GC)-treated Nb2-T lymphocytes in vitro, and PRL and GCs are elevated during stress, we investigated whether PRL protected T cells in vivo from GC-induced apoptosis. Adrenalectomized mice [PRL -/-, undetectable PRL; pituitary grafted PRL-/- (PRL-/-Graft), elevated PRL; and PRL+/-, normal PRL] were treated with dexamethasone (DEX) or PBS. Thymocytes and splenocytes were isolated and annexin V labeling of phosphatidylserine, DNA fragmentation, and caspase-3 activation were assessed as indices of apoptosis. Total thymocytes and CD4+ and CD8+ T cells obtained from DEX-treated PRL-/- mice exhibited significantly increased annexin V binding. In contrast, binding was not altered by DEX in PRL-/-Graft thymocytes. In addition, DEX induced classic DNA fragmentation in PRL-/- thymocytes. Elevated serum PRL reduced this effect. Thymocytes from DEX-treated PRL-/- mice exhibited increased caspase-3 activation, which was inhibited in cells from PRL-/-Graft mice. Finally, elevated expression of X-linked inhibitor of apoptosis, XIAP, was observed in thymi from DEX-treated PRL -/-Graft mice. This is the first demonstration that elevated PRL antagonizes apoptosis in thymocytes exposed to GCs in vivo. These observations suggest that, under conditions of increased GCs, such as during stress, elevated PRL functions physiologically to maintain survival and function of T-lymphocytes. [less ▲]

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See detailImproving spatial information extraction for local and regional authorities using Very-High-Resolution data - geometric aspects.
Devriendt, Dennis; Goossens, Rudi; De Wulf, Alain et al

in International Archives of Photogrammetry, Remote Sensing and Spatial Information Sciences (2003), 34(XXX),

The purpose of the presented research project is to investigate how present-day EO-technology can support local and regional decision-making, particularly in Belgium, and to develop prototype versions of ... [more ▼]

The purpose of the presented research project is to investigate how present-day EO-technology can support local and regional decision-making, particularly in Belgium, and to develop prototype versions of value-added products that fulfil some of the actual information needs, as expressed by Belgian authorities at the local and at the regional level. To accomplish this goal the proposal addresses both technical and user-oriented issues, and builds on the experience of five research teams, each with its own background and particular know-how. The most important objectives of the project are: - to define optimal methods for improved spatial information extraction from high- and very-high resolution data, based on innovative processing techniques; - to identify useful EO-applications at the level of local and regional decision making that are made possible by applying the information extraction methods that will be developed; in this case especially 3D information - to define and develop value-added core data products that will support these applications, and that can be consulted with easy-to-use, widely available IT-tools (CD-ROM, Internet, …). One of the technical research modules is focussing on the geometrical aspects of VHR data processing. In terms of spatial resolution, VHR data have the required level of detail to resolve individual objects in the landscape, in a similar way as airborne data. As such, they have the potential of becoming a useful data source for the extraction of detailed, object-related information, and for the production of large-scale cartographic reference data. The geometry of VHR sensor data, however, completely differs from the geometry of aerial photographs (Bethel et al., 2001). Research is going on to evaluate the geometric qualities of present and future VHR standard data products, from the moment they become available, and to examine what level of geometric accuracy is attained with these data, depending on image parameters, processing strategies, and terrain characteristics (Zhou and Li, 2000). The main objectives of the research module on geometric aspects of VHR data processing are: a) to define an optimal procedure for the derivation of envelope DSMs (Digital Surface Models) and ortho-photoplans from VHR data; b) to develop a theoretical model to study the effect of the oblique viewing angle of VHR data on image displacements caused by building height and relief; c) to evaluate the geometric accuracy of satellite-derived envelope DSMs and ortho-corrected image data in comparison with similar products obtained by means of large-scale aerial photography. The module about geometrical aspects is divided into six specific tasks. a) GPS database creation b) Creation of reference envelope DSMs based on aerial photography c) Ortho-rectification of VHR images and aerial photography based on reference DSMs d) Evaluation of the quality of VHR geo-referenced data e) Modelling of displacements caused by terrain morphology and sensor viewing angle f) Development of envelope DEMs from VHR stereoscopic imagery The project is now in the stage where the quality of the georeferenced and orthorectified data is evaluated. [less ▲]

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See detailVerso il coordinamento : formazione e innovazione nella Comunità francese del Belgio
Pirard, Florence ULg

in Musatti, T.; Mayer, S. (Eds.) Il coordinamento dei servizi educativi per l’infanzia. Una funzione emergente in Italia e in Europa (2003)

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