References of "2003"
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See detailEffects of hypoxia on stress proteins of the piglet brain at birth
Chiral, Magali; Grongnet, Jean-François; Plumier, Jean-Christophe ULg et al

Poster (2003)

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See detailFormulation of submicronic emulsions by using a high-pressure homogeniser
Roland, I; Evrard, Brigitte ULg; Erpicum, T et al

in Journal de Pharmacie de Belgique (2003), 57

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See detailL’anorexie comme une pathologie des rythmes
Gauthier, Jean-Marie ULg; Sami, Ali; Asselot, Hubert et al

in Rythme et pathologie organique (2003)

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See detailStatistique bayésienne des processus ponctuels marqués. Le rôle des variables latentes dans la démarche de modélisation.
Bernier, Jacques; Parent, Eric; Boreux, Jean-Jacques ULg

Conference (2003)

En statistique bayésienne le raisonnement conditionnel est à la base de la solidarité étroite entre modélisation et calcul par algorithmes MCMC. Un des aspects les plus fructueux de son utilisation est l ... [more ▼]

En statistique bayésienne le raisonnement conditionnel est à la base de la solidarité étroite entre modélisation et calcul par algorithmes MCMC. Un des aspects les plus fructueux de son utilisation est l'utilisation explicite des variables latentes ou cachées. On présente trois exemples de séries météorologiques représentées par des modèles de processus ponctuels marqués de complexité croissante. Sur ces exemples on montre la souplesse de modélisation et les facilités de calcul apportées par les variables latentes en relation avec les techniques "d'augmentation de données de Tanner". [less ▲]

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See detailModule de garantie de transmission
Reinbold, Pierre; Martin, Sylvain ULg; Bonaventure, Olivier et al

in ARTHUR - Manuel d'informatisation des urgences (2003)

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See detailEnantiomeric separation of aminoglutethimide by capillary electrophoresis using native cyclodextrins in single and dual systems
Abushoffa, A. M.; Fillet, Marianne ULg; Marini Djang'Eing'A, Roland ULg et al

in Journal of Separation Science (2003), 26(6-7), 536-542

Aminoglutethimide (AGT) is one of the few examples of chiral drugs that can be enantioseparated by capillary electrophoresis using any of the three native cyclodextrins: alpha-, beta-, or gamma-CD. A ... [more ▼]

Aminoglutethimide (AGT) is one of the few examples of chiral drugs that can be enantioseparated by capillary electrophoresis using any of the three native cyclodextrins: alpha-, beta-, or gamma-CD. A complete resolution of the enantiomers of this compound in cationic form could be achieved with each of the three CDs, using a pH 3 phosphoric acid-triethanolamine buffer. Affinity constants for AGT enantiomers with the three native CDs were determined, confirming that the highest selectivity was given by gamma-CD while the strongest complexation was obtained with beta-CD. However, an opposite affinity pattern was observed with the latter. Selectivity was lower for AGT enantiomers in dual CD systems, compared to that obtained with a single selector at its optimal concentration, which confirms that dual systems are of more limited interest when the two selectors have a similar effect on the analyte mobility. These results are in good agreement with those predicted using recently developed mathematical models. [less ▲]

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See detailAge, sex, and weight at weaning influence organ weight and gastrointestinal development of weanling pigs
Pluske, J. R.; Kerton, D. J.; Cranwell, P. D. et al

in Australian Journal of Agricultural Research (2003), 54(5), 515-527

The present study was designed to determine the interrelationships between sex, weaning age, and weaning weight on aspects of physiological and gastrointestinal development in pigs. Forty-eight Large ... [more ▼]

The present study was designed to determine the interrelationships between sex, weaning age, and weaning weight on aspects of physiological and gastrointestinal development in pigs. Forty-eight Large White x Landrace pigs were used in a factorial arrangement with the respective factors being: age at weaning ( 14 or 28 days), weight at weaning ( heavy or light), sex ( boar or gilt), and time after weaning ( 1, 7, and 14 days). At weaning, 48 pigs were removed from the sow; 16 pigs were then fasted for 24 h before euthanasia for determination of organ weights, gut histology, and enzymology, and 32 pigs were offered a high quality pelleted weaner diet ad libitum for subsequent assessment of organ weights, histology, and enzymology at 7 and 14 days after weaning. On Day 6 and 13 after weaning, 2 pigs from each group had their feed removed, and 24 h later were euthanased and similar measurements were taken. In general, the data highlighted the overall gastrointestinal underdevelopment of pigs weaned at 2 weeks of age and of pigs weaned light-for-age at either 2 or 4 weeks. Heavier body organs, gastrointestinal organs, and accessory digestive organs observed after weaning, except for the spleen, presumably reflected the increase in substrates available for cellular growth as feed intake increased after weaning, and the development of organs required to process this feed. Interestingly, the relative weights (% of liveweight) of the stomach and small intestine and, to a lesser extent, the caecum and colon, were greater in the light, 14-day-old weaned pigs, but these differences diminished with increasing time after weaning. Consistent effects due to age, weight, and sex were not observed for villous height and crypt depth, or for the specific activities of the brush-border and pancreatic enzymes measured. However, increases (P < 0.001) in the activities of maltase (P < 0.001), glucoamylase ( P < 0.001), and sucrase (P = 0.020) ( all expressed per gram of mucosa), and that of trypsin ( per gram of pancreas), occurred by 14 days after weaning. This most likely reflected the inducible nature of these enzymes in response to the increasing intake of substrates provided in the diet. In contrast, the specific activity of lactase declined (P = 0.012) in the first 14 days after weaning. These data suggest that pigs weaned at 2 weeks of age and pigs weaned light-for-age at either 2 or 4 weeks have a less developed gastrointestinal tract, and that its development after weaning might proceed differently to that of pigs weaned older and heavier. [less ▲]

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See detailT-cell reconstitution after unmanipulated, CD8-depleted or CD34-selected nonmyeloablative peripheral blood stem-cell transplantation.
Baron, Frédéric ULg; Schaaf-Lafontaine, Nicole ULg; Humblet-Baron, Stéphanie ULg et al

in Transplantation (2003), 76(12), 1705-13

BACKGROUND: We have previously shown that CD8 depletion or CD34 selection of peripheral blood stem cells (PBSC) reduced the incidence of acute graft-versus-host disease (GvHD) after nonmyeloablative stem ... [more ▼]

BACKGROUND: We have previously shown that CD8 depletion or CD34 selection of peripheral blood stem cells (PBSC) reduced the incidence of acute graft-versus-host disease (GvHD) after nonmyeloablative stem-cell transplantation (NMSCT). In this study, we analyze the effect of CD8 depletion or CD34 selection of the graft on early T-cell reconstitution. METHODS: Nonmyeloablative conditioning regimen consisted in 2 Gy total-body irradiation (TBI) alone, 2 Gy TBI and fludarabine, or cyclophosphamide and fludarabine. Patients 1 to 18 received unmanipulated PBSC, patients 19 to 29 CD8-depleted PBSC, and patients 30 to 35 CD34-selected PBSC. RESULTS: T-cell counts, and particularly CD4+ and CD4CD45RA+ counts, remained low the first 6 months after nonmyeloablative stem-cell transplantation (NMSCT) in all patients. CD34 selection (P<0.0001) but not CD8 depletion of PBSC significantly decreased T-cell chimerism. Donor T-cell count was similar in unmanipulated compared with CD8-depleted PBSC recipients but was significantly lower in CD34-selected PBSC recipients (P=0.0012). T cells of recipient origin remained stable over time in unmanipulated and CD8-depleted PBSC patients but expanded in some CD34-selected PBSC recipients between day 28 and 100 after transplant. Moreover, whereas CD8 depletion only decreased CD8+ counts (P<0.047), CD34 selection reduced CD3+(P<0.001), CD8+(P<0.016), CD4+ (P<0.001), and CD4+CD45RA+ (P<0.001) cell counts. T-cell repertoire was restricted in all patients on day 100 after hematopoietic stem-cell transplantation but was even more limited after CD34 selection (P=0.002). CONCLUSIONS: Despite of the persistence of a significant number of T cells of recipient origin, T-cell counts were low the first 6 months after NMSCT. Moreover, contrary with CD8 depletion of the graft that only affects CD8+ lymphocyte counts, CD34 selection dramatically decreased both CD8 and CD4 counts. [less ▲]

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See detailNouveau concept algorithmique pour un modèle de laminage à froid en régime mixte
STEPHANY, A.; Ponthot, Jean-Philippe ULg; COLLETTE, C. et al

in Proceedings of the 6ème colloque national en calcul des structures (2003)

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See detailThe fate of the adjacent motion segments after lumbar fusion.
Gillet, Philippe ULg

in Journal of Spinal Disorders & Techniques (2003), 16(4), 338-45

Lumbar spine fusion is a commonly performed procedure in various pathologic conditions of the spine. Its role remains debated, and moreover, delayed complications may occur, among which is transitional ... [more ▼]

Lumbar spine fusion is a commonly performed procedure in various pathologic conditions of the spine. Its role remains debated, and moreover, delayed complications may occur, among which is transitional segment alteration leading to recurrence of back pain, gross instability, and neurologic symptoms. Little is known about the long-term prevalence of this complication because of a lack of specific studies. We analyzed the fate of the transitional segments in a homogeneous group of patients operated on during a 14-year period for degenerative conditions of the lumbar spine resistant to conservative treatment. Follow-up ranged from 2 to 15 years. Seventy-five percent of our study group had a minimal 5-year follow-up. In this subgroup, 41% of the patients developed transitional segment alterations, and 20% needed a secondary operation for extension of the fusion. Potential risk factors such as postoperative delay, length of fusion, and spine imbalance were recognized. The frequency of delayed alterations of the adjacent segment and the severity of symptoms related to this complication in this study raise questions about the justification of fusion procedures in degenerative conditions of the spine without threatening instability. Data from the literature confirm the severity of the problem, but many uncertainties remain because of the lack of homogeneous and complete data on both the normal evolution of motion segments of the lumbar spine with age and the fate of the same segments when transformed in transitional segments. Future prospective studies on the subject are needed and must deal with homogeneous groups of patients. More reconstructive surgical procedures need to be developed to lessen the need for fusion procedures. [less ▲]

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See detailOndelettes et télédétection.
Charles, Catherine ULg

in Actes des XXXVèmes Journées de Statistiques (2003)

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See detailCómo vivir juntos. Notas de cursos y seminarios en el Collège de France (1976-1977)
Barthes, Roland; Willson, Patricia ULg

Book published by Siglo XXI Editores (2003)

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See detailLe Robinier faux-acacia en Wallonie : utopie ou réalité? Premiers résultats
Fourbisseur, Anne; Devillet, Stéphane; Jourez, Benoît ULg et al

in Forêt Wallonne (2003), (67), 12-23

Malgré son grand potentiel technologique et écologique, le Robinier faux-acacia (Robinia pseudacacia L.) est une essence sinon méconnue, du moins négligée en Région wallonne. Dans le contexte actuel où la ... [more ▼]

Malgré son grand potentiel technologique et écologique, le Robinier faux-acacia (Robinia pseudacacia L.) est une essence sinon méconnue, du moins négligée en Région wallonne. Dans le contexte actuel où la notion de gestion durable s’est imposée, certaines de ses propriétés, notamment écologiques, ouvrent la voie à une plus grande prise en considération de l’espèce. De plus, le robinier présente des caractéristiques remarquables, liées à sa vitesse de croissance et aux propriétés de son bois, et est susceptible, dans une certaine mesure, de trouver des débouchés très valorisants, par exemple dans des emplois réservés jusqu’à présent aux bois tropicaux. Cette essence mérite certainement un intérêt particulier, d’autant plus que la littérature ne présente pas d’argument précis en sa défaveur. La présence d’épines et la nécessité d’améliorer la morphologie de l’arbre ne sont certes pas des raisons suffisantes pour justifier l’absence d’expérimentation sylvicole en Région wallonne, mis à part les dispositifs installés voilà maintenant deux ans par l’Unité de Gestion des Ressources forestières et des Milieux naturels de la Faculté universitaire des Sciences agronomiques de Gembloux (FUSAGx) et par le Centre de Recherche de la Nature, des Forêts et du Bois, Direction de Technologie <br />du Bois (CRNFB, DTB). Un programme d’amélioration génétique pourrait en parallèle générer en quelques années un matériel de qualité en s’inspirant des recherches menées en Hongrie, pays à la pointe en matière de gestion du Robinier faux- acacia. Pour répondre à l’attente des estionnaires privés et publics, nous présentons une synthèse des connaissances relatives au robinier. Dans ce but, nous tenterons d’abord de cerner ses exigences stationnelles, et nous en déduirons les potentialités d’implantation de l’essence en Wallonie. Nous décrirons ensuite <br />la sylviculture appliquée au robinier en Hongrie et en France, pays réputés pour leur expérience dans le domaine, et verrons dans quelle mesure il est possible de profiter de cette expérience en Région wallonne. Nous détaillerons enfin les possibilités de valorisation de son bois. Les premiers résultats issus des dispositifs expérimentaux de sylviculture mis en place par la FUSAGx depuis <br />2 ans en Région wallonne seront inclus dans cet état des lieux et comparés aux expériences étrangères. [less ▲]

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See detailAdherence to various host cell lines of Mycoplasma bovis strains differing in pathogenic and cultural features
Thomas, Anne; Sachse, Konrad; Dizier, Isabelle ULg et al

in Veterinary Microbiology (2003), 91(2-3), 101-113

Mycoplasma bovis is known to be responsible for pneumonia and arthritis in calves, as well as mastitis in dairy cows. Despite clear evidence of its pathogenic potential, little is known about mechanisms ... [more ▼]

Mycoplasma bovis is known to be responsible for pneumonia and arthritis in calves, as well as mastitis in dairy cows. Despite clear evidence of its pathogenic potential, little is known about mechanisms of cytadherence and the molecular factors involved. The purpose of this work was to compare adherence rates of M. bovis field strains to different host cell lines and study the effects of cloning and sub-culturing M. bovis strains on their adherence properties. Eighteen metabolically labeled M. bovis strains isolated from different pathological backgrounds were examined in adherence trials using four different host cell lines, i.e. embryonic bovine lung (EBL), embryonic bovine trachea (EBTr), Madin Darby bovine kidney (MDBK) and rabbit kidney (RK) cells. Although large interstrain variations in adherence rates (3.4-19.1%) were measured they could not be correlated to the pathological background (pneumonia, arthritis or mastitis). Adherence rates to the fibroblast cell line (EBTr) were significantly lower than those to the three epithelial cell lines (EBL, MDBK and RK). The only non-pathogenic strain (221/89) exhibited lower adherence rates than three isolates from clinical mastitis. Interestingly, adherence rates were significantly reduced after in vitro passaging. In contrast, no effect of single cloning of strains on adherence was observed. There was no general correlation between expression of variable surface proteins (Vsps) as monitored by immunoblotting and adherence rates, although alterations in Vsp expression profiles were seen as a consequence of passaging. As there is probably a large number of adhesins, variable and non-variable, on the surface of M. bovis cells the issue is very complex, and the most active components have yet to be identified. [less ▲]

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See detailPhylogeny
Baudoin, Jean-Pierre ULg; Maquet, A.

in Plant and Soil (2003), 252(1), 55-128

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See detailL'iconographie du meurtre de saint Lambert de Liège
George, Philippe ULg

in Bischofsmord im Mittelalter. Murder of Bishops, 22 septembre 2000 (2003)

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See detailFactor-XIIIa-positive dendrocytes in drug-induced toxic epidermal necrolysis (Lyell's syndrome): paradoxical activation in skin and rarefaction in lymph nodes.
Paquet, Philippe ULg; Quatresooz, Pascale ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 206(4), 374-8

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell ... [more ▼]

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell infiltration. The precise pathomechanism of the disease remains unclear. METHODS: Skin specimens and peripheral and thoracic lymph nodes (LNs) were collected from 2 TEN patients. They were examined by conventional histology and immunohistochemistry using antibodies directed to factor XIIIa (dermal dendrocytes), CD1a (Langerhans cells), CD15 (granulocytes), CD20 (B lymphocytes), CD45RO (activated T lymphocytes), CD68 (macrophages) and the proliferation marker Ki-67. LNs from patients with mycosis fungoides, from subjects dead from acute cardiac failure or traumatic injuries, as well as metastasis-free sentinel LNs of cutaneous melanoma served as positive and negative controls. RESULTS: TEN LNs showed absence of germinal centers but a moderate hyperplasia of the paracortical T cell zone. Immunohistochemistry did not reveal any distinctive aspect in LN cellular densities between TEN and other control conditions except for the factor-XIIIa+ dendritic cells which were dramatically reduced in numbers in TEN LNs. This rarefaction in LNs contrasted with the great number of these cells in the skin of the same patients. CONCLUSION: The structure of TEN LNs rules out the involvement of an antibody-mediated response. As dendritic factor-XIIIa+ cells are involved in most cutaneous T-cell-mediated responses, their depletion in TEN LNs could explain the sparse lymphoid cell infiltrate in lesional TEN skin. [less ▲]

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