References of "2002"
     in
Bookmark and Share    
See detailLe reconditionnement physique du lombalgique chronique fréquentant une école du dos : expérience au CHU-Liège
Charlier, Marie; Demoulin, Christophe ULg; Tomasella, Marco ULg et al

in Actes du First International Symposium of the Belgian Back Society (2002, December)

Detailed reference viewed: 57 (5 ULg)
See detailLa réponse pénale du juge à l'auteur d'une infraction routière
Dantinne, Michaël ULg; Kellens, Georges ULg

in Actes du colloque: "Sécurité routière: quelle réponse pénale?" (2002, December)

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailRADAR: Ring-based adaptive discovery of active neighbour routers
Martin, Sylvain ULg; Leduc, Guy ULg

in Lecture Notes in Computer Science (2002, December), 2546

The RADAR protocol and its underlying neighbourhood discovery framework extend the ANTS toolkit by giving active nodes the ability to discover dynamically other active nodes close to them without relying ... [more ▼]

The RADAR protocol and its underlying neighbourhood discovery framework extend the ANTS toolkit by giving active nodes the ability to discover dynamically other active nodes close to them without relying on any configuration file. Such an automatic discovery is the key to administration of large or sparse active networks and the first step towards an efficient active routing. Active nodes will use their local IP routing table to run an extended ring search in their domain. An Additive Increase Multiplicative Decrease control allows RADAR to discover several neighbours per physical interface without searching too far away or fixing a maximum distance a priori. The protocol is complemented by a traffic-driven discovery that can grab capsules coming from unknown nodes (mainly outside the local domain) and trigger targetted probing of those addresses. [less ▲]

Detailed reference viewed: 46 (4 ULg)
Full Text
Peer Reviewed
See detailEU-MERCOSUR interregionalism: Facing Up to the South American Crisis and the Free Trade Area of the Americas
Santander, Sébastian ULg

in European Foreign Affairs Review (2002), 7

As part of their plans to diversify and globalize their foreign relations, the EU and MERCOSUR have been working to establish closer links. They have a project to create an interregional Association based ... [more ▼]

As part of their plans to diversify and globalize their foreign relations, the EU and MERCOSUR have been working to establish closer links. They have a project to create an interregional Association based on political dialogue, cooperation and trade issues. To understand the evolution of this interregional relationship, it is also important to take into account the USAs’ project, which seeks to create a hemispheric market for 2005 and in which MERCOSUR is participating. There is competition between Europe and the USA in the Southern Cone. While the EU has often provided support for institution building in MERCOSUR, the latter has frequently been destabilized by US regionalist strategy. The USA has often taken advantage of its special relationship with Argentina. However, the open crises that Argentina has faced since December 2001, and the US attitude towards the crises, appear to have affected the Buenos Aires foreign policy alignment with Washington. What geopolitical consequences could this have for the area? And what is the US position on this development? Has the EU taken advantage of the situation to reinforce its interregional partnership with MERCOSUR and to counteract US influence in the region? [less ▲]

Detailed reference viewed: 332 (4 ULg)
Full Text
Peer Reviewed
See detailCytokine production from sputum cells after allergenic challenge in IgE-mediated asthma
Bettiol, Jeanne; Sele, Jocelyne ULg; Henket, Monique ULg et al

in Allergy (2002), 57(12), 1145-1150

Background: Th2 cytokine production from airway cells is thought to govern the eosinophilic airways in ammation in allergic asthma. Induced sputum has become a widely used technique to assess airways in ... [more ▼]

Background: Th2 cytokine production from airway cells is thought to govern the eosinophilic airways in ammation in allergic asthma. Induced sputum has become a widely used technique to assess airways in ammation. Methods: By applying the technique of induced sputum to collect airways cells, we have assessed the spontaneous production of a set of cytokines, including interleukin-4, 6, 10, interferon-gamma and tumour necrosis factor-alpha 6 h after a bronchial allergenic hallenge with Dermatophagoides pteronyssinus (Dpt) in 12 sensitized asthmatics and compared the results obtained after inhalation of saline as control. A group of eight healthy non-allergic subjects was enrolled to control for any non-specific effect of Dpt. Cytokines were measured by a dynamic immunoassay during a 24-h sputum cell culture. Results: Allergen challenge in sensitized asthmatics caused an acute and a late bronchospasm together with a rise in sputum eosinophil counts. Afterwards allergen sputum cells from allergic asthmatics displayed a rise in their production of IL-4 (P < 0.01), IL-6 (P < 0.05) and IL- 10 (P < 0.05) when compared to saline. By this time sputum generation of IL- 4 in atopic asthmatics was greater than in healthy subjects (P < 0.001). Furthermore, in allergic asthmatics there was a strong correlation between the rise in interleukin-4 production from sputum cells and the rise in sputum eosinophils (r = 0.87, P < 0.001). Conclusions: Sputum cell culture is a useful model to assess cytokine production in allergic asthmatics who show a marked up-regulation of Th2 cytokines following acute allergen exposure. The rise in sputum eosinophil count following allergen challenge strongly correlates with the rise in IL-4 generation from sputum cells. [less ▲]

Detailed reference viewed: 46 (6 ULg)
Full Text
Peer Reviewed
See detailAsthénie et troubles visuels chez un peintre de 48 ans
Pirenne, Danièle ULg; Mairiaux, Philippe ULg

in Revue Médicale de Liège (2002), 57(12), 785-8

Tiredness is a common complaint which may have multiple causes, sometimes difficult to ascertain. As occupational activities can play a major role in the incidence of various diseases, failure to ... [more ▼]

Tiredness is a common complaint which may have multiple causes, sometimes difficult to ascertain. As occupational activities can play a major role in the incidence of various diseases, failure to investigate the patient's work history may hinder an adequate patient care. In the clinical case described hereafter, the patient symptoms could eventually be ascribed to a psycho-organic syndrome (POS) caused by the chronic exposure to organic solvents in the painting material used. This syndrome is non specific, evolves with time in an insidious manner, and, in its last stages, may cause non reversible brain damages. When facing non typical neurological symptoms in a working age adult, one has thus to consider the possibility of this diagnosis since the workers populations exposed to solvents are large in several occupations, and because the recent legal recognition in Belgium of this syndrome as an occupational disease does provide some interesting means for a better follow-up and protection of the patients concerned. [less ▲]

Detailed reference viewed: 104 (7 ULg)
Full Text
Peer Reviewed
See detailBrain function in the vegetative state
Laureys, Steven ULg; Antoine, S.; Boly, Mélanie ULg et al

in Acta Neurologica Belgica (2002), 102(4), 177-185

Positron emission tomography (PET) techniques represent a useful tool to better understand the residual brain function in vegetative state patients. It has been shown that overall cerebral metabolic rates ... [more ▼]

Positron emission tomography (PET) techniques represent a useful tool to better understand the residual brain function in vegetative state patients. It has been shown that overall cerebral metabolic rates for glucose are massively reduced in this condition. However, the recovery of consciousness from vegetative state is not always associated with substantial changes in global metabolism. This finding led us to hypothesize that some vegetative patients are unconscious not just because of a global loss of neuronal function, but rather due to an altered activity in some critical brain regions and to the abolished functional connections between them. We used voxel-based Statistical Parametric Mapping (SPM) approaches to characterize the functional neuroanatomy of the vegetative state. The most dysfunctional brain regions were bilateral frontal and parieto-temporal associative cortices. Despite the metabolic impairment, external stimulation still induced a significant neuronal activation (i.e., change in blood flow) in vegetative patients as shown by both auditory click stimuli and noxious somatosensory stimuli. However this activation was limited to primary cortices and dissociated from higher-order associative cortices, thought to be necessary for conscious perception. Finally, we demonstrated that vegetative patients have impaired functional connections between distant cortical areas and between the thalami and the cortex and, more importantly, that recovery of consciousness is paralleled by a restoration of this cortico-thalamo-cortical interaction. [less ▲]

Detailed reference viewed: 90 (29 ULg)
Full Text
Peer Reviewed
See detailChanges in the arginine-vasopressin immunoreactive systems in male mice lacking a functional aromatase gene
Plumari, L.; Viglietti-Panzica, C.; Allieri, F. et al

in Journal of Neuroendocrinology (2002), 14(12), 971-978

In male rodents, the arginine-vasopressin-immunoreactive (AVP-ir) neurones of the bed nucleus of the stria terminalis (BNST) and medial amygdala are controlled by plasma testosterone levels (decreased ... [more ▼]

In male rodents, the arginine-vasopressin-immunoreactive (AVP-ir) neurones of the bed nucleus of the stria terminalis (BNST) and medial amygdala are controlled by plasma testosterone levels (decreased after castration and restored by exogenous testosterone). AVP transcription in these nuclei is increased in adulthood by a synergistic action of the androgenic and oestrogenic metabolites of testosterone and, accordingly, androgen and oestrogen receptors are present in both BNST and medial amygdala. We used knockout mice lacking a functional aromatase enzyme (ArKO) to investigate the effects of a chronic depletion of oestrogens on the sexually dimorphic AVP system. Wild-type (WT) and ArKO male mice were perfused 48 h after an i.c.v. colchicine injection and brain sections were then processed for AVP immunocytochemistry. A prominent decrease (but not a complete suppression) of AVP-ir structures was observed in the BNST and medial amygdala of ArKO mice by comparison with the WT. Similarly, AVP-ir fibres were reduced in the lateral septum of ArKO mice and but not in the medial preoptic area, a region where the AVP system is not sexually dimorphic in rats. No change was detected in the supraoptic and suprachiasmatic nuclei. However, a decrease in AVP-ir cell numbers was however, detected in one subregion of the paraventricular nucleus. These data support the hypothesis that the steroid-sensitive sexually dimorphic AVP system of the mouse forebrain is mainly under the control of aromatized metabolites of testosterone. [less ▲]

Detailed reference viewed: 36 (1 ULg)
Full Text
Peer Reviewed
See detailComment je traite ... par hormonotherapie des patientes developpant des complications thrombo-emboliques lors du traitement d'un cancer du sein par tamoxifene
Pelerin, D.; Silvestre, R. M.; Jerusalem, Guy ULg et al

in Revue Médicale de Liège (2002), 57(12), 755-6

Thromboembolic complications are well known side effects of treatment with tamoxifen in patients with breast cancer. The authors review the pathophysiology and the risk factors that increase the ... [more ▼]

Thromboembolic complications are well known side effects of treatment with tamoxifen in patients with breast cancer. The authors review the pathophysiology and the risk factors that increase the probability to develop these complications. The most appropriate treatment is discussed. [less ▲]

Detailed reference viewed: 35 (0 ULg)
Full Text
Peer Reviewed
See detailMacrophage migration inhibitory factor (MIF) expression in human glioblastomas correlates with vascular endothelial growth factor (VEGF) expression
Munaut, Carine ULg; Boniver, Jacques ULg; Foidart, Jean-Michel ULg et al

in Neuropathology & Applied Neurobiology (2002), 28(6), 452-460

Macrophage migration inhibitory factor (MIF) is a peptide released upon hypothalamo-pituitary stimulation that acts as a potent endogenous antagonist of the glucocorticoid inhibition of acute inflammatory ... [more ▼]

Macrophage migration inhibitory factor (MIF) is a peptide released upon hypothalamo-pituitary stimulation that acts as a potent endogenous antagonist of the glucocorticoid inhibition of acute inflammatory response and subsequent antigen-specific response. MIF also sustains tumour growth as it promotes angiogenesis, overcomes p53-mediated cell growth arrest and inhibits tumour-specific immune responses. Using quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and immunohistochemistry, we studied MIF expression in 35 human glioblastomas and two normal brains. We compared these results with the expression of vascular endothelial growth factor (VEGF), the most potent angiogenic factor in glioblastomas. We detected MIF in normal cortical neurons and glial cells. All glioblastomas were positive for MIF mRNA with expression levels similar to or higher than those of normal brain. MIF immunoreactivity was seen mainly in tumour cells and less frequently in hyperplastic endothelial cells. The expressions of MIF and VEGF mRNA were strongly correlated (P < 0.0001). Our results demonstrate the expression of MIF in human glioblastomas, and indicate a close relationship with VEGF expression. This is of particular interest given the potential modulation of MIF by glucocorticosteroids. [less ▲]

Detailed reference viewed: 53 (3 ULg)
Full Text
Peer Reviewed
See detailHematurie causee par un "nutcracker syndrome" ou "syndrome du casse-noisettes": confirmation peroperatoire de sa realite
Andrianne, Robert ULg; Limet, Raymond ULg; Waltregny, David ULg et al

in Progrès en Urologie (2002), 12(6), 1323-6

Nutcracker syndrome should be considered in the case of left ureteric haematuria based on computed tomography with vascular reconstruction of the hilar region of the kidney. The best confirmation is ... [more ▼]

Nutcracker syndrome should be considered in the case of left ureteric haematuria based on computed tomography with vascular reconstruction of the hilar region of the kidney. The best confirmation is obtained by studying the pressure gradient between the left renal vein and the inferior vena cava during cavography. Various modalities of surgical treatment have been proposed by a few authors, but have been criticised by some authors who question the clinical reality of this syndrome and the efficacy of treatment. The decision to operate may be difficult and other investigations may be useful to confirm the diagnosis. We report the case of a patient in whom the diagnosis of nutcracker syndrome was confirmed intraoperatively by the immediate appearance of massive, reversible haematuria induced by clamping of the renal vein during vein dissection and augmentation plasty. In the light of this original case, we believe that a preoperative percutaneous haematuria provocation test by temporary obstruction of the left renal vein during venography could allow a more formal diagnosis of nutcracker syndrome when this syndrome is highly suspected. [less ▲]

Detailed reference viewed: 160 (2 ULg)
Full Text
Peer Reviewed
See detailIncreased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord
Krautstrunk, M.; Scholtes, Félix ULg; Martin, Didier ULg et al

in Acta Neuropathologica (2002), 104(6), 592-600

Keratan sulphate proteoglycan (KSPG) is a developmentally regulated barrier molecule, directing axonal growth during central nervous system (CNS) formation. The possible re-expression and functional ... [more ▼]

Keratan sulphate proteoglycan (KSPG) is a developmentally regulated barrier molecule, directing axonal growth during central nervous system (CNS) formation. The possible re-expression and functional significance of KSPG in preventing axon regeneration following spinal cord injury (SCI) is poorly understood. In the present investigation, the spatio-temporal expression of KSPG was studied following experimental SCI. There was no indication of sparing of axons at the lesion epicentre following severe compression injury. By 7 days post operation (p.o.) a diffuse increase of KSPG immunoreactivity (KSPG-IR) was observed in the parenchyma surrounding the lesion. This was followed by a delayed (21-28 days p.o.) and largely heterogeneous increase of KSPG-IR in the lesion epicentre, which revealed both cellular and extracellular matrix-like distribution patterns. Although no re-growth of anterogradely labelled corticospinal axons was observed, many 200-kDa neurofilament (NF)-positive axon could be detected growing into the connective tissue scar. This phase of spontaneous axonal re-growth was closely associated with a framework of glial cells (including Schwann cells from damaged local spinal nerve roots) that had migrated into the lesion site. The spontaneous nerve fibre re-growth could be detected in both KSPG-rich and KSPG-poor territories. The present data suggest that the lesion-induced up-regulation of KSPG-IR may have contributed to the lack of corticospinal axon re-growth. However, the lack of any direct spatio-temporal correlation between the distribution of raised KSPG-IR and spontaneous NF-positive axonal regeneration suggests that at least some populations of axons can resist the putative inhibitory effects of this extracellular matrix molecule. [less ▲]

Detailed reference viewed: 38 (11 ULg)
Full Text
Peer Reviewed
See detailLa carcinomatose hepatique du cancer colorectal: actualites therapeutiques
Polus, Marc ULg; Honore, Pierre ULg; De Roover, Arnaud ULg et al

in Revue Médicale de Liège (2002), 57(12), 771-8

Important progress has been made in the treatment of liver metastases of advanced colorectal cancer. Surgery with curative intent, when possible, shows evidence of prolonged survival. Response rate and ... [more ▼]

Important progress has been made in the treatment of liver metastases of advanced colorectal cancer. Surgery with curative intent, when possible, shows evidence of prolonged survival. Response rate and overall survival can be improved with modern polychemotherapy. Cytotoxic drug combinations and sequential treatments sometimes make surgery possible for initially non resectable lesions. Impact of loco-regional treatment such as hepatic arterial infusion chemotherapy must be defined in randomised trials. Radiofrequency ablation is also currently evaluated in clinical trials. In this review the benefit of each treatment is discussed. [less ▲]

Detailed reference viewed: 197 (6 ULg)
Full Text
Peer Reviewed
See detailOptimization of the separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media using univariate and multivariate approaches
Servais, Anne-Catherine ULg; Fillet, Marianne ULg; Chiap, Patrice ULg et al

in Journal of Separation Science (2002), 25(15-17), 1087-1095

The separation of four beta-blocking drug substances (atenolol, sotalol, betaxolol, and metoprolol) selected as model basic analytes has been investigated in non-aqueous capillary electrophoresis (NACE ... [more ▼]

The separation of four beta-blocking drug substances (atenolol, sotalol, betaxolol, and metoprolol) selected as model basic analytes has been investigated in non-aqueous capillary electrophoresis (NACE) using the principle of ion-pair formation. Camphorsulphonate was selected as the counter-ion in a background electrolyte (BGE) made up of formate buffer in a mixture of acetonitrile/methanol or acetonitrile/ethanol. The influence on resolution of the concentration of the counter-ion, the nature and proportion of the organic solvents, as well as the concentration of the ionic components of the BGE was first studied by a univariate approach. An experimental design was then applied to estimate possible quadratic effects and first-order interactions. To identify the most important factors affecting the separation of the four beta-blockers, a two-level fractional factorial design with 16 experimental points was applied as a screening test. A three factor Box-Behnken design with 12 experimental points was used to predict and optimize the selectivity. Finally the optimal conditions obtained by the univariate and the multivariate, approaches were compared. [less ▲]

Detailed reference viewed: 26 (1 ULg)
Full Text
Peer Reviewed
See detailSevere lower gastrointestinal bleeding in Crohn's disease: Successful control with infliximab
Berlaiche, J.; Louis, Edouard ULg

in American Journal of Gastroenterology (2002), 97(12), 3210-3211

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailSite effect analysis around the seismically induced Ananevo, Rockslide, Kyrgyzstan
Havenith, Hans-Balder ULg; Jongmans, D.; Faccioli, E. et al

in Bulletin of the Seismological Society of America (2002), 92(8), 3190-3209

In 1911, the surface-wave magnitude 8.2 Kemin earthquake hit northeastern Tien Shan (Kyrgyzstan), close to the cities of Bishkek and Almaty, the capitals of Kyrgyzstan and Kazakhstan, respectively ... [more ▼]

In 1911, the surface-wave magnitude 8.2 Kemin earthquake hit northeastern Tien Shan (Kyrgyzstan), close to the cities of Bishkek and Almaty, the capitals of Kyrgyzstan and Kazakhstan, respectively. Several hundreds of people were killed by the earthquake, some by indirect effects such as landslides and mudflows. A particular but nonfatal landslide triggered by the Kemin event was a rockslide in the vicinity of Ananevo, north of lake Issyk Kul (Kyrgyzstan) rockslide located above the fault zone activated in 1911. In the summer of 1999, a geophysical-seismological field trip was organized to study geology and to record seismic ground motions on and around the Ananevo rockslide. The work was part of project assessing seismogenic landslide hazard in northern Kyrgyzstan, based on various case studies of slope failures in connection with site-specific ground-motion dynamics. The geophysical investigations consisted of seismic refraction tests processed as 2D seismic tomographies and surface-wave inversion, which were combined to build a 3D geophysical model of the landslide site. Ground motions from small earthquakes were analyzed using several techniques to define site effects over the mountain massif. Both H/V and standard spectral ratios indicated lower dominant frequencies with stronger amplification in the crest region with respect to the mountain slope. These effects could be partially simulated by I D, 2D, and 3D finite-element modeling. By comparing the numerical results with the experimental data, the presence of a surficial low-velocity layer of varying thickness appeared to be the key factor controlling the ground motion around the rockslide. [less ▲]

Detailed reference viewed: 49 (2 ULg)
Full Text
Peer Reviewed
See detailThe in situ formation of a new initiator system for the syndiotactic anionic polymerization of methyl methacrylate in toluene at 0°C
Zundel, Thomas; Teyssié, Philippe; Jérôme, Robert ULg

in Polymer (2002), 43(25), 7191-7193

This paper reports on an efficient 'in-situ' one pot synthesis of an initiatior/ligand adduct, which can be used to initiate the anionic polymerization of methyl methacrylate in toluene at 0 °C ... [more ▼]

This paper reports on an efficient 'in-situ' one pot synthesis of an initiatior/ligand adduct, which can be used to initiate the anionic polymerization of methyl methacrylate in toluene at 0 °C. Predominantly syndiotactic PMMA is formed. [less ▲]

Detailed reference viewed: 25 (4 ULg)
Full Text
Peer Reviewed
See detailThe north-eastern Polish anorthosite massifs: petrological, geochemical and isotopic evidence for a crustal derivation
Wiszniewska, Janina; Claesson, Stefan; Stein, Holly et al

in Terra Nova (2002), 14(6), 451-460

Deeply buried 1.5 Ga Polish anorthosites, accessible only by bore holes, reveal diagnostic features of some massif-type anorthosites (polybarism, jotunitic parent magma), diapirically emplaced in the mid ... [more ▼]

Deeply buried 1.5 Ga Polish anorthosites, accessible only by bore holes, reveal diagnostic features of some massif-type anorthosites (polybarism, jotunitic parent magma), diapirically emplaced in the mid crust together with the rapakivi granites of the EW-trending Mazury complex, intruded along a major crustal discontinuity. Geochemical modelling and isotope data corroborate recent experimental work on the basaltic system in dry conditions: the source rock of the parental magma is a gabbronorite, necessarily lying in the lower crust. Since no Archaean crust is known in the region, high initial Os-188/Os-187 ratios for sulphide-oxide isochrons and negative epsilon(Nd) values are best accounted for by melting a similar to 2.0 Ga mafic crust. [less ▲]

Detailed reference viewed: 33 (8 ULg)
Full Text
See detailOn the Model Validation in Nonlinear structural Dynamics,
Kerschen, Gaëtan ULg

Doctoral thesis (2002)

Detailed reference viewed: 53 (12 ULg)
See detailLe Secret des Géants
Beckers, Albert ULg

Scientific conference (2002, December)

Detailed reference viewed: 5 (0 ULg)