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See detailPurification and characterization of a pregnancy-associated glycoprotein (ovPAG-6) from sheep placenta removed between 66 to 100 days of gestation.
El Amiri, B.; Remy, B.; Melo de Sousa, Noelita ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(1), 12-13

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See detailApproche clinique des ictères et des suspicions d’insuffisance hépatique aiguë chez le cheval : une étude rétrospective sur 40 cas
Amory, Hélène ULg; Sandersen, Charlotte ULg; Delguste, Catherine ULg et al

in Proceedings of the Annual meeting of the French Equine Veterinary Association (AVEF) (2002)

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See detailEffet placebo, effet nocebo: comment la science explique les guérions miraculeuses
Quertemont, Etienne ULg

Scientific conference (2002)

L’effet placebo est habituellement considéré comme l’ensemble des réponses psychologiques et physiologiques des patients à une substance inerte. On parle d’effet placebo lorsque cette réponse constitue un ... [more ▼]

L’effet placebo est habituellement considéré comme l’ensemble des réponses psychologiques et physiologiques des patients à une substance inerte. On parle d’effet placebo lorsque cette réponse constitue un effet bénéfique pour la santé et d’effet nocebo lorsque les conséquences sont néfastes. Cependant, les phénomènes placebo/nocebo recouvrent plus largement tous les effets du contexte environnemental qui ne résultent pas spécifiquement du traitement médical administré. Une partie de ce qu’on nomme effet placebo/nocebo peut s’expliquer par des mécanismes de conditionnement pavlovien. Des effets placebo résultant du conditionnement pavlovien sont ainsi régulièrement mis en évidence sur des animaux de laboratoire. Au conditionnement pavlovien s’ajoute également chez l’être humain un facteur plus spécifiquement psychologique : l’effet des croyances et des attentes (expectancies). De nombreuses études ont ainsi démontré que les croyances et les attentes des patients exercent des effets objectifs sur leur santé qui se traduisent par des modifications biologiques. Nous examinerons plus particulièrement les mécanismes qui permettent à ces influences psychologiques de modifier l’état biologique d’un sujet. Parmi ceux-ci, le système immunitaire ainsi que les opiacés endogènes qui régulent la douleur semblent particulièrement influencés par l’état psychologique. Finalement nous montrerons comment les phénomènes placebo/nocebo apportent une explication rationnelle à plusieurs exemples de guérisons miraculeuses ou pseudo-scientifiques. Parmi ces exemples nous examinerons plus particulièrement le rôle important que joue l’effet placebo dans l’homéopathie. [less ▲]

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See detailMesure de la charge psychosociale et du stress professionnel auprès du personnel du groupe FN Herstal
Italiano, Patrick ULg; Peters, Stéphanie ULg

Report (2002)

Le rapport analyse les résultats d'une enquête sur la charge psychosociale au sein de l'entreprise et détaille les situations-problème qui y sont liées.

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See detailPerspectives de dialogue entre des neuromédiateurs et les kératinocytes.
Pierard-Franchimont, Claudine ULg; Faska, N.; Nikkels, Arjen ULg et al

in Dermatologie Actualité (2002), 65

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ... [more ▼]

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ces molécules sont synthétisées in situ et sont connues pour avoir des récepteurs spécifiques et exprimer une activité biologique dans cet organe. Certaines exercent un impact fonctionnel sur les kératinocytes. Il s’agit en fait de systèmes paracrines neuro-kératinocytaires et autocrines par lesquels les kératinocytes expriment de nombreux récepteurs pour les neuromédiateurs qu’ils libèrent eux-mêmes. [less ▲]

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See detailLe Diable et les vierges
Dor, Juliette ULg

in Carruthers, Leo (Ed.) Anges et démons dans la littérature anglaise du Moyen Âge (2002)

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See detail- La bande dessinée muette et le texte
Paques, Frédéric ULg

in Art&Fact (2002), 21

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See detailDrug resistance among therapy-naive HIV-infected patients studied by sequencing and VERSANT (TM) HIV-1 resistance assays (LiPA) has limited impact on treatment response
Derdelinckx, I.; Van Laethem, K.; Maes, B. et al

in Antiviral therapy (2002), 7(Suppl. 1), 181

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See detailEconomic evaluation of chronic hepatitis C treatment by interferon-ribavirin combination therapy in Belgium
Delwaide, Jean ULg

in Acta Gastro-Enterologica Belgica (2002), 65(4), 233-236

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response ... [more ▼]

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response is associated with long-term disappearance of the C virus, improvement of histology, improvement in quality of life and, most than likely, a reduction in the risk of premature death or infection-linked complications. This therapy is, however, expensive and the number of potentially treatable patients is high in view of the relatively high prevalence of the disease in the population. An economic evaluation is thus indispensable in order, on the one hand, to assess the cost-effectiveness ratio of the treatment (i.e. the extra cost to be paid for obtaining the greater effectiveness provided by the therapeutic combination in comparison with absence of treatment or treatment by interferon alone), and, on the other hand, to estimate practically the global cost of treatment for Belgium (i.e. the annual expense for society according to the number of patients treated per year). [less ▲]

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See detailEcology of Salmonella in slaughter pigs digestive tract and study of the contamination of carcasses
Boudry, Christelle ULg; Korsak Koulagenko, Nicolas ULg; Jacob, Benoit et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 353-360

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal ... [more ▼]

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal shedding of Salmonella. No sample was positive but at the slaughterhouse, the analysis of tonsils and certain parts of the digestive tract (mesenterial lymph nodes, ileum and large intestine content) revealed that 70% of the pigs were positive. The strains isolated from the faecal samples of the large intestine and from tonsils were identical, which might indicate that there has been an oral contamination from pig to pig due to the shedding of Salmonella or a carriage of different strains in different organs. The mesenterial lymph nodes (40 % positive) were contaminated by strains which were different from those from the faecal samples and tonsils. Salmonella strains were only found on the swabs of one carcass. A complementary assay has shown the negative role played by the scalding step. This latter may contaminate the oral and rectal cavities of slaughtered animals. This entire study reveals the difficulty to predict the contamination risk at the slaughterhouse from the analysis of finishing pigs faecal samples. Therefore, a better knowledge of the carriage and the shedding of Salmonella during the finishing period and during the slaughter is necessary to minimise meat contamination. [less ▲]

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See detailLes crises alimentaires et les systèmes de prévision au Sahel
Andrea, Di vecchia; Patrizio, Vignaroli; Djaby, Bakary ULg

Conference (2002)

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See detailRecommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma
Holgate, ST; Bousquet, J; Chung, KF et al

in International Journal of Pharmaceutical Medicine (2002), 16

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See detailPhysiotherapy and Neuropsychology : What about the honeymoon ?
DELRUE, Gaël ULg

Conference (2002)

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See detailDeterministic and stochastic modelling for protection zone delineation
Rentier, Céline; Dassargues, Alain ULg

in Calibration and Reliability in Groundwater Modelling: A Few Steps Closer to Reality (2002)

Protection zones delimited by isochrones are often computed using calibrated groundwater flow and transport models. In heterogeneous formations, all direct (hard) and indirect (soft) data must be used ... [more ▼]

Protection zones delimited by isochrones are often computed using calibrated groundwater flow and transport models. In heterogeneous formations, all direct (hard) and indirect (soft) data must be used optimally. Approaches involving in situ pumping and tracer tests, combined with geophysical and/or other geological observations, should be developed. In a deterministic framework, the calibrated model is considered to be the best representation of reality at the current investigation stage, but uncertainty of the results is not quantified. Using stochastic methods, a range of equally likely isochrones can be produced, allowing us to quantify the influence of our knowledge on the aquifer parameters on protection-zone uncertainty. Furthermore, integration of soft data in a conditioned stochastic generation process, possibly associated with an inverse modelling procedure, can reduce the resulting uncertainty. Proposed is a stochastic methodology for protection-zone delineation, integrating hydraulic conductivity measurements (hard data), head observations and electrical resistivity data (soft data). [less ▲]

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See detailAre all glitazones the same?
Van Gaal, Luc; Scheen, André ULg

in Diabetes/Metabolism Research & Reviews (2002), 18 Suppl 2

This supplement focuses on the benefits of targeting insulin resistance through therapy with a new class of oral antidiabetic agents, the thiazolidinediones (TZDs) or 'glitazones'. There are important ... [more ▼]

This supplement focuses on the benefits of targeting insulin resistance through therapy with a new class of oral antidiabetic agents, the thiazolidinediones (TZDs) or 'glitazones'. There are important differences between the three TZD class members that warrant discussion to enable physicians to make rational and informed therapeutic choices between the agents. Overall the TZDs appear to be similar in their effects on blood glucose, as all class members have demonstrated effective glycaemic control, both as monotherapy and in combination with sulphonylureas, metformin or exogenous insulin. The safety profiles of the three agents are more diverse, with what appear to be 'TZD class effects', (probably mediated via activation of peroxisome proliferator-activated receptor gamma [PPAR gamma]) and 'TZD-specific effects', which are unique to each agent and may be a consequence of differing chemical structures. While rosiglitazone and pioglitazone share some class effects with troglitazone, they have several characteristics that define them as unique agents. By tackling the control of type 2 diabetes through direct effects on insulin resistance, the TZDs represent an important new therapeutic tool for healthcare professionals. [less ▲]

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