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See detailRadiation-associated synovial-sarcoma: clinicopathological and molecular analysis of two cases.
Egger, J-F; Coindre, J-M; Benhattar, J et al

in Modern Pathology : An Official Journal of the United States & Canadian Academy of Pathology, Inc (2002), 15(9), 998-1004

Development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant ... [more ▼]

Development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant peripheral nerve sheath tumors, and angiosarcomas are most frequently encountered. Radiationassociated synovial sarcomas are exceptional. We report the clinicopathologic, immunohistochemical, and molecular features of two radiationassociated synovial sarcomas. One tumor developed in a 42-year-old female 17 years after external irradiation was given for breast carcinoma; the other occurred in a 34-year-old female who was irradiated at the age of 7 years for a nonneoplastic condition of the left hand. Both lesions showed morphologic features of monophasic spindle cell synovial sarcoma, were immunoreactive for cytokeratins, epithelial membrane antigen, CD99, CD117 (c-kit), and bcl-2 and bore the t(X;18) (SYT-SSX1) translocation. We conclude that synovial sarcoma has to be added to the list of radiation-associated soft-tissue sarcomas. Mod Pathol 2002;15(9):998–1004 [less ▲]

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See detailMurine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo
Van Valckenborgh, E.; De Raeve, H.; Devy, L. et al

in British Journal of Cancer (2002), 86(5), 796-802

Multiple myeloma is a B cell malignancy. Recently, it has been demonstrated that bone marrow samples of patients with multiple myeloma display an enhanced angiogenesis. The mechanisms involved seem to be ... [more ▼]

Multiple myeloma is a B cell malignancy. Recently, it has been demonstrated that bone marrow samples of patients with multiple myeloma display an enhanced angiogenesis. The mechanisms involved seem to be multiple and complex. We here demonstrate that the murine 5T multiple myeloma models are able to induce angiogenesis in vitro by using a rat aortic ring assay and in vivo by determining the microvessel density. The rat aortic rings cultured in 5T multiple myeloma conditioned medium exhibit a higher number of longer and more branched microvessels than the rings cultured in control medium. In bone marrow samples from 5T multiple myeloma diseased mice, a statistically significant increase of the microvessel density was observed when compared to bone marrow samples from age-matched controls. The angiogenic phenotype of both 5T multiple myeloma cells could be related, at least in part, to their capacity to produce vascular endothelial growth factor. These data clearly demonstrate that the 5T multiple myeloma models are good models to study angiogenesis in multiple myeloma and will allow to unravel the mechanisms of neovascularisation, as well as to test new putative inhibitors of angiogenesis. [less ▲]

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See detailPostmenopausal aging of the sebaceous follicle: a comparison between women receiving hormone replacement therapy or not.
Pierard, Claudine ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2002), 204(1), 17-22

BACKGROUND: The endocrine control of sebaceous follicles is complex in women. During aging, a decline in sebum output is often experienced. However, some women report increased seborrhea after the ... [more ▼]

BACKGROUND: The endocrine control of sebaceous follicles is complex in women. During aging, a decline in sebum output is often experienced. However, some women report increased seborrhea after the menopause. OBJECTIVE: In this study, the follicular reservoir function was studied during the first decade following the menopause. METHODS: Four evaluations were made at 3-week intervals in two parallel age-matched groups of 50 postmenopausal women receiving hormone replacement therapy (HRT) or not. The Sebumeter served to measure the casual sebum level and the sebum excretion rate on the forehead. In addition, a Visioscan equipped with an ultraviolet-recording camera was used with and without lipid-sensitive tapes interposed between the camera and the skin surface. Follicular openings and sebum pore patterns were studied by image analysis. RESULTS: There was enormous diversity among individual values of sebum output at the skin surface. In untreated women, a significant decline in sebum excretion rate accompanied by an increase in both the sebum replacement time and the mean pore size were evidenced during the first decade after the menopause. The sebum excretion rate and casual level showed a wide range of interindividual differences early after the menopause. These physiological changes were less prominent in women receiving HRT. CONCLUSION: Postmenopausal aging affects the sebum production, but HRT does not significantly control the complex process of seborrhea. However, HRT mitigates the progressive enlargement of the openings of the sebum follicular reservoir. [less ▲]

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See detailApplication of the fast multipole method to the 2D finite element-boundary element analysis of electromechanical devices
V Sabariego, Ruth ULg; Gyselinck, J.; Geuzaine, Christophe ULg et al

in Proceedings of the 10th International Symposium on Numerical Field Calculation in Electrical Engineering (IGTE 2002) (2002)

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See detailSoft project: a new ocean forecasting system based on satellite data
Pascual, A.; Orfila, A.; Alvarez, A. et al

Conference (2002)

The aim of the SOFT project is to develop a new ocean forecasting system by using a combination of satellite data, evolutionary programming and numerical ocean models. To achieve this objective two steps ... [more ▼]

The aim of the SOFT project is to develop a new ocean forecasting system by using a combination of satellite data, evolutionary programming and numerical ocean models. To achieve this objective two steps are proposed: (1) to obtain an accurate ocean forecasting system using genetic algorithms based on satellite data; and (2) to integrate the above new system into existing deterministic numerical models. Evolutionary programming will be employed to build "intelligent" systems that, learning from the past ocean variability (provided by satellite data) and considering the present ocean state, will be able to infer near future ocean conditions. Validation of the forecast skill will be carried out by comparing the forecasts fields with satellite and in situ observations. Validation with satellite observations will provide the expected errors in the forecasting system. Validation with in situ data will indicate the capabilities of the satellite based forecast information to improve the performance of the numerical ocean models. This later validation will be accomplished considering in situ measurements in a specific oceanographic area at two different periods of time. The first set of observations will be employed to feed the hybrid systems while the second set will be used to validate the hybrid and traditional numerical model results. Keywords: forecasting, satellite data, empirical orthogonal functions, numerical models, genetic algorithms, neural networks, Mediterranean Sea. [less ▲]

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See detailChandra X-ray Observations of the Jovian System
Elsner, R. F.; Waite, J. H.; Crary, F. et al

Conference (2002)

High-spatial resolution Chandra x-ray obsrvations have demonstrated that most of Jupiter's northern auroral x-rays come from a hot spot located significantly poleward of the latitudes connected to the ... [more ▼]

High-spatial resolution Chandra x-ray obsrvations have demonstrated that most of Jupiter's northern auroral x-rays come from a hot spot located significantly poleward of the latitudes connected to the inner magnetosphere. This hot spot appears fixed in magnetic latitude and longitude and coincides with a region exhibiting anomalous ultraviolet and infrared emissions. The hot spot also exhibited approximately 45 minute quasi-periodic oscillations, a period similar to those reported for high-latitude radio and energetic electron bursts observed by near-Jupiter spacecraft. These results invalidate the idea that jovian auroral x-ray emissions are mainly excited by steady precipitation of energetic heavy ions from the inner magnetosphere. Instead, the x-rays appear to result from currently unexplained processes in the outer magnetosphere that produce highly localized and highly variable emissions over an extremely wide range of wavelengths. The Chandra observations also revealed for the first time x-ray emission (about 0.1 GW) from the Io Plasma Torus, as well as very faint x-ray emission (about 1-2 MW) from the Galilean moons Io, Europa, and possibly Ganymede. The emission from the moons is almost certainly due to Kalpha emission of surface atoms (and possibly impact atoms) excited by the impact of highly energetic protons, oxygen, and sulfur atoms and ions from the Torus. The Torus emission is less well understood at present, although bremsstrahlung from the non-thermal tail of the electron distribution may provide a significant fraction. In any case, further observations, already accepted and in the process of being planned, with Chandra, some with the moderate energy resolution of the CCD camera, together with simultaneous Hubble Space Telescope observations and hopefully ground-based IRTF observations should soon provide greater insight into these various processes. [less ▲]

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See detailL'énergie de chauffage et de climatisation en ville
Marique, Anne-Françoise ULg

Master's dissertation (2002)

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See detailLa réalité morale du sociologue : le cognitivisme de Raymond Boudon
Jacquemain, Marc ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2002), 94-95-96

Raymond Boudon defends that the social actor holds overall rational beliefs : we have "good reasons" for most of our beliefs. But he also defends the idea that those "good reasons" can lead to "moral ... [more ▼]

Raymond Boudon defends that the social actor holds overall rational beliefs : we have "good reasons" for most of our beliefs. But he also defends the idea that those "good reasons" can lead to "moral truths". How then can he avoid pure platonism (the idea that "values" exist objectively in a world of their own) ? When confronting to to the task of defending through concrete examples how we can differentiate "good reasons" from bad ones, he says that good reasons are widely shared. But then the idea of objectivity of values dissolves in a loose theory of opinion, that's to say "doxa", which is the very contrary of platonic ideas. So the intent to point to "objective" values seems to lead either to pure dogmatism or to pure relativism. [less ▲]

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See detailPolyester layered silicate nanohybrids by controlled grafting polymerization
Lepoittevin, Bénédicte; Pantoustier, Nadège; Alexandre, Michaël ULg et al

in Journal of Materials Chemistry (2002), 12(12), 3528-3535

Poly( epsilon-caprolactone) (PCL) layered silicate nanohybrids were synthesized by ring opening polymerization of epsilon-caprolactone according to a well-controlled coordination-insertion mechanism ... [more ▼]

Poly( epsilon-caprolactone) (PCL) layered silicate nanohybrids were synthesized by ring opening polymerization of epsilon-caprolactone according to a well-controlled coordination-insertion mechanism. Montmorillonites were surface-modified by non functional (trimethylhexadecylammonium) and hydroxy functional alkylammonium cations, i.e., (2-hydroxyethyl) dimethylhexadecylammonium. The hydroxy functions available at the clay surface were activated into tin( II or IV) or Al(III) alkoxide initiators for lactone polymerization, thus yielding surface-grafted PCL chains. The surface-grafted PCL chains were recovered by an ionic exchange reaction with lithium chloride and they were analyzed by size exclusion chromatography. The PCL molar mass was measured as a function of the hydroxy content of the clay that was modulated by exchanging the Na cations with mixtures of non-functional and hydroxy functional ammonium cations of different compositions. Nanohybrids were also characterized by small-angle X-ray diffraction, transmission electron microscopy and thermogravimetry. The PCL molar mass and the nanocomposite morphology (i.e., exfoliation and/or intercalation) were readily tuned by the content of the hydroxy groups available at the clay surface. Surface-grafted aluminium trialkoxide species proved highly efficient in initiating polymerization that leads to PCL chains of controlled molar mass and narrow molecular weight distribution with polydispersity indices as low as 1.2. [less ▲]

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See detailLe nouveau paysage institutionnel fiscal de la Belgique
Bourgeois, Marc ULg

Poster (2002)

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See detailLes contes de Grimm: présentation de quelques inconnus en français qui témoignent de l'entrée des Contes de l'Enfance et du Foyer dans la littérature de jeunesse
Delbrassine, Daniel ULg

in Cahiers du CLPCF (2002), 2

Présentation et traduction de contes retranchés dans le recueil des Grimm

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See detailLes charpentes du XIe au XIXe siècle: typologie et évolution en France du Nord et en Belgique
Hoffsummer, Patrick ULg

Book published by Monum, Editions du patrimoine (2002)

Resarch has made considerable progress in the field of history of roofs,particularly thanks the contribution of dendrochronology. This book is the result of collaboration between architects, university ... [more ▼]

Resarch has made considerable progress in the field of history of roofs,particularly thanks the contribution of dendrochronology. This book is the result of collaboration between architects, university sholars, Belgian and French dendrochronologists, and offers a synthesis with regard to carpentry from 11th through the 19th century, from north of the Loire to Belgium. It contains a typological and chronological classification with 300 examples of carpentry constructions, and a catalogue of beautiful models preserved at the Center for reaserch on Historical Monuments in PAris. It is a valuable reference work for all those - art historians, architects, building restores - who are interested in historic carpentry [less ▲]

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See detailVade-mecum sur les stratégies de communication.
Doppagne, Véronique ULg; Hertay, Alain; Seron, Nathalie et al

Learning material (2002)

Ce vade-mecum comprend une introduction présentant les fondements théoriques de la séquence didactique expérimentale (16 pages), une retranscription des extraits-vidéo (9 pages), un dossier d'activités ... [more ▼]

Ce vade-mecum comprend une introduction présentant les fondements théoriques de la séquence didactique expérimentale (16 pages), une retranscription des extraits-vidéo (9 pages), un dossier d'activités (36 pages) et un "carnet de bord" pour les enseignants (12 pages). [less ▲]

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See detailNeoliberaal literatuuronderzoek. Thomas Vaessens over zijn methode, lecturen en stijl
Spinoy, Erik ULg

in Tijdschrift voor Nederlandse Taal- en Letterkunde (2002), 118(3),

This article is a reaction to Thomans Vaessens defence of his book Circus Dubio & Schroom.

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See detailRelics of the saints - Recent publications and new perspectives
George, Philippe ULg

Book published by Revue Belge Philologie Histoir (2002)

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See detailPotential of the NDSC in support of the Kyoto Protocol: Examples from the station Jungfraujoch, Switzerland
Zander, Rodolphe ULg; Mahieu, Emmanuel ULg; Servais, Christian ULg et al

in Van Ham, J.; Baede, A. P. M.; Guicherit, R. (Eds.) et al Non-CO2 Greenhouse Gases: Scientific Understanding, Control Options and Policy Aspects (2002)

This paper gives a brief description and “raison d’être” of the Network for the Detection of Stratospheric Change (NDSC) as well as its key research tasks to address the broader goal of monitoring ... [more ▼]

This paper gives a brief description and “raison d’être” of the Network for the Detection of Stratospheric Change (NDSC) as well as its key research tasks to address the broader goal of monitoring atmospheric changes and to identify their causes and related impacts on mankind’s environment. While the Network has primarily focussed, thus far, on monitoring the ozone layer and assessing global compliance with the Montreal Protocol, ongoing implementations and new capabilities have enabled it to adapt to more recent political developments such as the Kyoto Proto-col on substances affecting the climate system. Examples of activities in support of the latter are reported, based on infrared solar observations at the Jungfraujoch station. [less ▲]

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See detailQuantitative dilatometric analysis of intercritical annealing in a low-silicon TRIP steel
Zhao, Lie; Kop, T. A.; Rolin, Valéry et al

in Journal of Materials Science (2002), 37

In this work, an evaluation method to calculate the austenite fraction during continuous heating and isothermal annealing from dilatometric data is proposed. By means of a single reference measurement to ... [more ▼]

In this work, an evaluation method to calculate the austenite fraction during continuous heating and isothermal annealing from dilatometric data is proposed. By means of a single reference measurement to determine a scaling factor correcting for experimental errors, a framework is created to determine the austenite fraction as a function of time and temperature. In the evaluation of the dilatometric data the effect of the changing carbon concentration in austenite phase is taken into account. The method is applied to dilatometric data for a 0.16C-1.5Mn-0.4Si (wt%) low-silicon transformation induced plasticity (TRIP) multiphase steel. Three typical dilatometric data are obtained by heating the material to 750°C, 800°C or 900°C, which leads to three different microstructures consisting of (1) ferrite, cementite and austenite, (2) ferrite and austenite and (3) full austenite, respectively. The calculated results using the proposed new method are compared with the results from thermodynamic analysis and those from quantitative microscopic analysis. Significant inter-test discrepancies are observed. [less ▲]

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