References of "2002"
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See detailHeidegger et la question de la chose. Esquisse d'une lecture interne
Dewalque, Arnaud ULg

Master's dissertation (2002)

Reconstruction génétique des réflexions de Heidegger sur le concept de "chose", en particulier sur sa portée métaphysique (par opposition au concept d'objet).

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See detailThe intracellular tyrosine residues of the ATP-gated P2X(1) ion channel are essential for its function.
Oury, Cécile ULg; Toth-Zsamboki, Emese; Watanabe, Hiroyuki et al

in FEBS Letters (2002)

In this study, we mutated the four highly conserved intracellular tyrosine residues of the P2X(1) ion channel were mutated into phenylalanine. Simultaneous electrophysiological and calcium measurements in ... [more ▼]

In this study, we mutated the four highly conserved intracellular tyrosine residues of the P2X(1) ion channel were mutated into phenylalanine. Simultaneous electrophysiological and calcium measurements in transfected human embryonic kidney (HEK 293) cells indicated that Y362F and Y370F mutants were non-functional, despite their proper plasma membrane expression. The Y16F and Y363F mutants retained 2.2% and 26% of the wild-type P2X(1) activity, respectively. However, no tyrosine phosphorylation was detected on Western blots of P2X(1) immunoprecipitates derived either from HEK 293 cell lysates or from human platelets, expressing P2X(1) endogenously. Thus, Y16, Y362, Y363 and Y370 are required for the appropriate three-dimensional structure and function of the intracellular P2X(1) domains. [less ▲]

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See detailPathogenic Escherichia coli strains from dogs and cats : IV) - General discussion
Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (2002), 146(4, AUG-SEP), 219

This manuscript reviews the current knowledge on the main classes of pathogenic Escherichia coli in dogs and cats: type 1 necrotoxigenic strains (NTEC1), adhesin-positive strains (AdEC), enteropathogenic ... [more ▼]

This manuscript reviews the current knowledge on the main classes of pathogenic Escherichia coli in dogs and cats: type 1 necrotoxigenic strains (NTEC1), adhesin-positive strains (AdEC), enteropathogenic strains (EPEC) and enterotoxigenic strains (ETEC). They represent primary or secondary (to other bacterial, parasitic and/or viral infections) infectious agents. NTEC1 and AdEC are the most frequent and are responsible for intestinal, urinary tract and invasive infections, while EPEC and ETEC limit their infections to the intestinal tract. ETEC are the less frequent but EPEC are more and more often observed. The specific virulence factors and other properties of these pathogenic E. coli strains are similar to those of their bovine, human and porcine counterparts, for their identity and their genetic determinism. This similarity allows the use of an identical approach in their diagnosis and typing. But for some NTEC1, AdEC and EPEC strains the similarity is so close that it also raises the question of their zoonotic potential, though there is up to now no epidemiological evidence of such cross contamination of man by canine or feline pathogenic E. coli (or vice versa). [less ▲]

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See detailHistoire de la principauté de Liège
Demoulin, Bruno ULg

Book published by Privat (2002)

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See detailMemory kernels and effective Hamiltonians from time dependent methods. II. Vibrational predissociation
Brems, Vincent; Desouter, Michèle ULg

in Journal of Chemical Physics (2002), 116

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See detailBlood oxygen binding in hypoxaemic calves
Cambier, Carole ULg; Clerbaux; Detry, Bruno et al

in Veterinary Research (2002), 33(3), 283-290

Blood oxygen transport and tissue oxygenation were studied in 28 calves from the Belgian White and Blue breed (20 healthy and 8 hypoxaemic ones). Hypoxaemic calves were selected according to their high ... [more ▼]

Blood oxygen transport and tissue oxygenation were studied in 28 calves from the Belgian White and Blue breed (20 healthy and 8 hypoxaemic ones). Hypoxaemic calves were selected according to their high respiratory frequency and to their low partial oxygen pressure (PaO2) in the arterial blood. Venous and arterial blood samples were collected, and 2,3-diphosphoglycerate, adenosine triphosphate, chloride, inorganic phosphate and hemoglobin concentrations, and pH, PCO, and PO2 were determined. An oxygen equilibrium curve (OEC) was measured in standard conditions, for each animal. The arterial and venous OEC were calculated, taking body temperature, pH and PCO2 values in arterial and venous blood into account. The oxygen exchange fraction (OEF%), corresponding to the degree of blood desaturation between the arterial and the venous compartments, and the amount of oxygen released at the tissue level by 100 mL of blood (OEF Vol%) were calculated from the arterial and venous OEC combined with the PO2 and hemoglobin concentration. In hypoxaemic calves investigated in this study, the hemoglobin oxygen affinity, measured under standard conditions, was not modified. On the contrary, in vivo acidosis and hypercapnia induced a decrease in the hemoglobin oxygen affinity in arterial blood, which combined to the decrease in PaO2 led to a reduced hemoglobin saturation degree in the arterial compartment. However, this did not impair the oxygen exchange fraction (OEF%), since the hemoglobin saturation degree in venous blood was also diminished. [less ▲]

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See detailPrévention et traitement des nausées et vomissements après chimiothérapie anticancéreuse
Brasseur, Edmond ULg; Silvestre, Rose-Marie; Jerusalem, Guy ULg et al

in Médecine et Hygiène (2002), 60

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See detailSystems Biology - A Glossary from two perspectives
Haubelt, A.; Bullinger, Eric ULg; Sauter, T. et al

Poster (2002)

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See detailWave packet propagation for constrained molecular systems. Spectroscopic applications to triatomic molecules
Lauvergnat, David; Justum, David; Desouter, Michèle ULg et al

in Journal of Molecular Structure : Theochem (2002), 577

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See detailOn Deriving a Hybrid Model for Carbohydrate Uptake in Escherichia Coli
Bullinger, Eric ULg; Sauter, T.; Allgöwer, F. et al

in Proc. 15th IFAC World Congress (2002)

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See detailInclusion Complexes of Cyproterone Acetate with Cyclodextrins in Aqueous Solution
Henry de Hassonville, Sandrine; Perly, Bruno; Piel, Géraldine ULg et al

in Journal of Inclusion Phenomena and Macrocyclic Chemistry (2002), 44

Cyproterone acetate (CPA) is a steroidal antiandrogen with a progestogenic activity. Given that this molecule has a very poor water solubility (2.1 μg/mL), different cyclodextrins (CDs) were tested to ... [more ▼]

Cyproterone acetate (CPA) is a steroidal antiandrogen with a progestogenic activity. Given that this molecule has a very poor water solubility (2.1 μg/mL), different cyclodextrins (CDs) were tested to form inclusion complexes and to increase solubility. Two different techniques were compared to study the affinity between CPA and CDs: phase-solubility studies and NMR spectroscopy. The stoichiometry and the stability constant could be determined for most complexes with the aid of phase-solubility studies. The greatest increase in solubility was achieved with the methylated β-CDs, but hydroxypropylated β- and γ -CDs also gave enhanced solubilities. 1H-NMR studies showed a solubility increase similar to that found with phase-solubility studies. The proof of inclusion in the 2,6-dimethyl-β-CD (DIMEB) was shown by 1H-NMR and t-ROESY spectra. [less ▲]

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See detailPharma clinics. Le médicament du mois. L'imiquimod (Aldara): un immunomodulateur pour la peau.
Hermanns-Le, Trinh ULg; Nikkels, Arjen ULg; Uhoda, Isabelle et al

in Revue Médicale de Liège (2002), 57(2), 116-8

Imiquimod is the first drug of a new therapeutic class encompassing cutaneous immune response modifiers. This molecule induces the synthesis and release of macrophage-related cytokines. It boosts some ... [more ▼]

Imiquimod is the first drug of a new therapeutic class encompassing cutaneous immune response modifiers. This molecule induces the synthesis and release of macrophage-related cytokines. It boosts some local immune responses. These properties are used to treat cutaneous viral condylomas. Other prospective therapeutic goals are presently scrutinized. [less ▲]

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See detailThe assessment of third metacarpal bone speed of sound measurements in young exercising thorougbreds
Carstanjen, B; Langlois, P; Detilleux, Johann ULg et al

in Proceedings of the European Society of the Veterinary Society (ESVOT) (2002)

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See detailHeurs et malheurs de cisterciennes... L'abbaye de La Ramée entre 1566 et 1790
Henneau, Marie-Elisabeth ULg

in Coomans, Thomas (Ed.) La Ramée, abbaye cistercienne en Brabant wallon (2002)

See detailLa suppression de la communauté de La Ramée en 1796 et la vente de l'abbaye
Henneau, Marie-Elisabeth ULg

in Coomans, Thomas (Ed.) La Ramée, abbaye cistercienne en Brabant wallon (2002)

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See detailIsolation ad Characterization of osteocalcin in horses
Carstanjen, B; Wattiez, R; Amory, Hélène ULg et al

in Proceedings of the ECVS meeting 2002 (Resident Forum) (2002)

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See detailVers un nouveau Droixhe
Frankignoulle, Pierre ULg; Stevens, Barbara

in Cahiers de l'Urbanisme (Les) (2002), 39

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See detailEntre terres et cieux..., le temps des fondations (13e-14e s.)
Henneau, Marie-Elisabeth ULg

in Coomans, Thomas (Ed.) La Ramée, abbaye cistercienne en Brabant wallon (2002)

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See detailHeat shock proteins. I : Classification and roles in pathological processes
Wirth, Delphine; Gustin, Pascal ULg; Drion, Pierre ULg et al

in Annales de Médecine Vétérinaire (2002), 146(4), 201-216

All living systems have evolved mechanisms to maintain homeostasis in the face of rapid environmental changes. When exposed to elevated temperatures, most of the cells activate the synthesis of a specific ... [more ▼]

All living systems have evolved mechanisms to maintain homeostasis in the face of rapid environmental changes. When exposed to elevated temperatures, most of the cells activate the synthesis of a specific group of proteins called Heat Shock Proteins (Hsps). This heat shock response, under control of specific transcription factors, the Heat Shock factors (HSF), is an evolutionarily conserved mechanism, from bacteria to humans. Heat Shock Proteins are classified into families according to their molecular weight (Hsp 25, 40, 70, 90, 105). They play the role of molecular chaperones by binding and protecting other molecules (proteins, RNAs). The function of Hsp is to prevent accumulation of non-native proteins either by assisting proper folding of polypeptides or by driving them to proteosome pathway for degradation. Hsps are involved in various pathological processes that are accompanied by protein alterations such as chronic or degenerative diseases. This review describes structural and functional characteristics of the six main Hsps classes. It also focuses on their respective role in highly studied pathologies. The diversity of Hsps implications in these diseases explains that they became recently a strategic target in development of new therapeutic strategies. [less ▲]

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