References of "2002"
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See detailLe coffret - reliquaire de l’église Saint Etienne de Waha
Van Ruymbeke, Muriel ULg

in Châsses - reliquaires en Wallonie, Premier regard (2002)

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See detailEveil des sociétés civiles en milieu urbain et organisations non gouvernementales: les exemples de Cotonou et de Lubumbashi
Pirotte, Gautier ULg; Poncelet, Marc ULg

in Autrepart : Revue de Sciences Sociales au Sud (2002), (23), 73-88

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See detailShort- and long-term advantages of an alternative ontogenetic pathway
Denoël, Mathieu ULg; Hervant, F.; Schabetsberger, R. et al

in Biological Journal of the Linnean Society (2002), 77(1), 105-112

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body ... [more ▼]

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body condition between paedomorphic and metamorphic Alpine newts (Triturus alpestris, Caudata, Amphibia) in four populations. Because we found a strong correlation between fat reserves and body condition, we used this last parameter as an indicator of long-term gains. In all studied sites, paedomorphic females showed higher body condition than metamorphic ones. Paedomorphic males were also at advantage in two populations. Paedomorphs exhibited higher energy intakes than metamorphs in two populations and similar gains in two others. Our results support unifying theories that predict the occurrence of facultative paedomorphosis in varied habitats as paedomorphs exhibited better energy balance than metamorphs. This work shows the need for considering integrative parameters such as body condition in the comparative study of performances when studying developmental heterochronies. (C) 2002 The Linnean Society of London, Biological Journal of the Linnean Society, 2002, 77, 105-112. [less ▲]

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See detailOn the specificity of cyclodextrin complexes detected by electrospray mass spectrometry
Gabelica, Valérie ULg; Galic, Nives; De Pauw, Edwin ULg

in Journal of the American Society for Mass Spectrometry (2002), 13(8), 946-953

alpha-cyclodextrin complexes with linear alpha,omega-dicarboxylic acids were investigated by electrospray mass spectrometry. These hydrophobic complexes are known to have an equilibrium binding constant ... [more ▼]

alpha-cyclodextrin complexes with linear alpha,omega-dicarboxylic acids were investigated by electrospray mass spectrometry. These hydrophobic complexes are known to have an equilibrium binding constant that increases with the diacid chain length. However, the electrospray mass spectrometry (ES-MS) spectra showed that the relative intensity of the complex did not vary significantly with chain length. This contradiction is caused by a contribution of nonspecific adducts to the signal of the complex in ES-MS. In order to estimate the contribution of nonspecific adducts to the total intensity of the complexes with alpha-cyclodextrin, the comparison was made between alpha-cyclodextrin and maltohexaose, the latter being incapable of making inclusion complexes in solution. The signal observed for complexes between diacids and maltohexaose can only result from nonspecific electrostatic aggregation, and is found to be more favorable with the shorter diacids. This is also supported by MS/MS experiments. A procedure is described which allows estimation of the contribution of the nonspecific complex in the spectra of the complexes with alpha-cyclodextrin by using the relative intensity of the complex with maltohexaose. The contribution of the specific complex to the total signal intensity is found to increase with the diacid chain length, which is in agreement with solution behavior. [less ▲]

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See detailHydro-mechanical behavior of fractures: 2D, F.E.M. modeling
Guiducci, Chiara; Pellegrino, Antonio; Radu, Jean-Pol ULg et al

in Auriault, J. L.; Geindreau, C.; Royer, P. (Eds.) Poromechanics II (2002)

A numerical approach for modeling the coupled hydro-mechanical fracture behavior is proposed. The movement of fluids through rock fractures and consequently the evolution of their hydraulic conductivity ... [more ▼]

A numerical approach for modeling the coupled hydro-mechanical fracture behavior is proposed. The movement of fluids through rock fractures and consequently the evolution of their hydraulic conductivity is an important subject in many petroleum related activities, mainly concerning the change of well productivity during the reservoir life. It is well known that the flow in the fractures is strongly controlled by the fracture apertures. Recent investigations on the distribution of the apertures in natural fractures suggest that the cubic law can, better than the Darcy law, predict the fluid flux through rough walled fractures as long as the appropriate average fracture aperture is used. A finite element code is developed to predict the influence that the stresses variation in the fracture has on the distributed hydraulic conductivity field. The proposed model combines the stochastic cubic law with a non-linear deformation function (hyperbolic) that is suggested to describe the stress-closure/opening curves of the joints and that allows to couple together the hydraulic and the mechanic fracture behavior. The relationships used and the validity of the present model are tested by means of the comparison between experimental data and numerical predictions (Bart 2000) in various bound-ary and loading conditions. Comparisons between the proposed new model and a no coupled one have also been performed. They show that the proposed coupled model allows for a more realistic description of the fracture behavior. [less ▲]

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See detailA randomized comparison of the value of additional stenting after optimal balloon angioplasty for long coronary lesions: final results of the additional value of NIR stents for treatment of long coronary lesions (ADVANCE) study.
Serruys, Patrick W.; Foley, David P.; Suttorp, Martin Jan et al

in Journal of the American College of Cardiology (2002), 39(3), 393-9

OBJECTIVES: We sought to investigate the clinical benefit of additional stent implantation after achieving an optimal result of balloon angioplasty (BA) in long coronary lesions (>20 mm). BACKGROUND: Long ... [more ▼]

OBJECTIVES: We sought to investigate the clinical benefit of additional stent implantation after achieving an optimal result of balloon angioplasty (BA) in long coronary lesions (>20 mm). BACKGROUND: Long coronary lesions are associated with increased early complications and late restenosis after BA. Stenting improves the early outcome, but stent restenosis is also related to both lesion length and stent length. METHODS: A total of 437 patients with a single native lesion 20 to 50 mm in length were included and underwent BA, using long balloons matched to lesion length and vessel diameter (balloon/artery ratio 1.1) to achieve a diameter stenosis (DS) <30% by on-line quantitative coronary angiography (QCA). "Bail-out stenting" was performed for flow-limiting dissections or >50% DS. Patients in whom an optimal BA result was achieved were randomized to additional stenting (using NIR stents) or no stenting. The primary end point was freedom from major adverse cardiac events (MACE) at nine months, and core laboratory QCA was performed on serial angiograms. RESULTS: Bailout stenting was necessary in 149 patients (34%) and was associated with a significantly increased risk of peri-procedural infarction (p < 0.02). Among the 288 randomized patients, the mean lesion length was 27+/-9 mm, and the vessel diameter was 2.78+/-0.52 mm. The procedural success rate was 90% for the 143 patients assigned to BA alone (control group), as compared with 93% in the 145 patients assigned to additional stenting (stent group), which resulted in a superior early minimal lumen diameter (0.54 mm, p < 0.001) and led to reduced angiographic restenosis (27% vs. 42%, p = 0.022). Freedom from MACE at nine months was 77% in both groups. CONCLUSIONS: A strategy of provisional stenting for long coronary lesions led to bailout stenting in one-third of patients, with a threefold increase in peri-procedural infarction. Additional stenting yielded a lower angiographic restenosis rate, but no reduction in MACE at nine months. [less ▲]

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See detailClassical and Bayesian inference in neuroimaging: Applications
Friston, Karl J; Glaser, Daniel E; Henson, Richard NA et al

in Neuroimage (2002), 16(2), 484-512

In Friston et al. ((2002) Neuroimage 16: 465-483) we introduced empirical Bayes as a potentially useful way to estimate and make inferences about effects in hierarchical models. In this paper we present a ... [more ▼]

In Friston et al. ((2002) Neuroimage 16: 465-483) we introduced empirical Bayes as a potentially useful way to estimate and make inferences about effects in hierarchical models. In this paper we present a series of models that exemplify the diversity of problems that can be addressed within this framework. In hierarchical linear observation models, both classical and empirical Bayesian approaches can be framed in terms of covariance component estimation (e.g., variance partitioning). To illustrate the use of the expectation-maximization (EM) algorithm in covariance component estimation we focus first on two important problems in fMRI: nonsphericity induced by (i) serial or temporal correlations among errors and (ii) variance components caused by the hierarchical nature of multisubject studies. In hierarchical observation models, variance components at higher levels can be used as constraints on the parameter estimates of lower levels. This enables the use of parametric empirical Bayesian (PEB) estimators, as distinct from classical maximum likelihood (ML) estimates. We develop this distinction to address: (i) The difference between response estimates based on ML and the conditional means from a Bayesian approach and the implications for estimates of intersubject variability. (ii) The relationship between fixed- and random-effect analyses. (iii) The specificity and sensitivity of Bayesian inference and, finally, (iv) the relative importance of the number of scans and subjects. The forgoing is concerned with within- and between-subject variability in multisubject hierarchical fMRI studies. In the second half of this paper we turn to Bayesian inference at the first (within-voxel) level, using PET data to show how priors can be derived from the (between-voxel) distribution of activations over the brain. This application uses exactly the same ideas and formalism but, in this instance, the second level is provided by observations over voxels as opposed to subjects. The ensuing posterior probability maps (PPMs) have enhanced anatomical precision and greater face validity, in relation to underlying anatomy. Furthermore, in comparison to conventional SPMs they are not confounded by the multiple comparison problem that, in a classical context, dictates high thresholds and low sensitivity. We conclude with some general comments on Bayesian approaches to image analysis and on some unresolved issues. [less ▲]

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See detailModeling the Martian ionosphere using the Total Electron Content measurement by the NEIGE/NETLANDER experiment
Morel, Laurent; Witasse, Olivier; Warnant, René ULg et al

in Proceedings of the XXVII URSI General Assembly (2002)

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See detailLa logique de la désurbanisation : les aptitudes aux déplacements et les formes urbaines
Halleux, Jean-Marie ULg

in De Keersmaecker, M.-L. (Ed.) Les coûts de la désurbanisation (2002)

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See detailInternet est mort. Vive internet!
Choffray, Jean-Marie ULg

Article for general public (2002)

La crise économique et financière que nous traversons depuis deux ans ne diffère en rien de celles que notre monde a connues au cours de sa longue histoire (Malkiel, 2000). De tels ajustements sont ... [more ▼]

La crise économique et financière que nous traversons depuis deux ans ne diffère en rien de celles que notre monde a connues au cours de sa longue histoire (Malkiel, 2000). De tels ajustements sont nécessaires chaque fois que notre système économique doit s’adapter à des changements technologiques majeurs. La longueur atypique de cette crise et son ampleur - plusieurs milliers de milliards de dollars de capitalisation boursière perdus – soulignent toutefois l’importance exceptionnelle des ajustements qu’engendrent l’adoption et la diffusion de ces technologies nouvelles. [less ▲]

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See detailDual finite element formulations taking eddy currents in lamination stacks into account
Dular, Patrick ULg; Gyselinck, J.; Geuzaine, Christophe ULg et al

in Proceedings of the 5th Brazilian Conference on Electromagnetics, CBMag 2002 (2002)

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See detailComment je traite ... une polyarthrite rhumatoïde. L'avènement d'une nouvelle ère thérapeutique: les anticorps anti-TNF-alpha
Kaiser, Marie-Joëlle ULg; Malaise, Michel ULg

in Revue Médicale de Liège (2002), 57(8), 486-492

Rheumatoid arthritis (RA) is the most frequent autoimmune inflammatory arthropathy. Chronic synovial inflammation usually results in cartilage destruction, bone erosion and subsequent joint deformities ... [more ▼]

Rheumatoid arthritis (RA) is the most frequent autoimmune inflammatory arthropathy. Chronic synovial inflammation usually results in cartilage destruction, bone erosion and subsequent joint deformities with impaired physical function. These consequences are more or less delayed by standard disease-modifying antirheumatic drugs (DMARDs). A better knowledge of the basic mechanisms of the disease and new biomolecular tools led to the development of novel biological agents including TNF alpha blockers. TNF alpha is a key inflammatory cytokine that plays a critically important role in the pathogenesis of RA. TNF alpha blockers brought dramatic improvements in efficacy of RA treatment. Here we will review the pathophysiological elements of RA wich explain the therapeutic efficacy of these TNF alpha blockers and we will describe in details the molecules, Remicade (Infliximab) and Enbrel (Etanercept), wich will be very soon used in daily practice in Belgium. [less ▲]

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See detailApplication of RAP-PCR and cDNA-AFLP to isolate genes of Candida oleophila (strain O) induced by the presence of galacturonic acid.
Massart, Sébastien ULg; Sens-Espel, Roser; Lepoivre, Philippe ULg et al

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2002), 25(10), 399-402

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See detailEditorial. Ecrire...
Hindryckx, Geneviève ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 11-12

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See detailMetabolic stress as a paradigm to elucidate genotype-environment interaction in psychosis
Marcelis, Machteld; Cavalier, Etienne ULg; Gielen, Jacques et al

in Acta Psychiatrica Scandinavica (2002), 105(Suppl. 411), 91

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See detailLe droit des régimes matrimoniaux en pratique
Leleu, Yves-Henri ULg; Casman, Hélène; Verbeke, Alain

Book published by Kluwer (2002)

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See detailContribution à l'étude de la physiopathologie du diabète 2
Paquot, Nicolas ULg

Post doctoral thesis (2002)

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See detailDeviant trajectories at the turning point between adolescence and adulthood
Born, Michel ULg; Gavray, Claire ULg

in Brochu, S. (Ed.) Drugs and crime deviant pathways (2002)

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See detailLiquidation des créances et récompenses au titre d'investissements immobiliers
Leleu, Yves-Henri ULg

in Leleu, Yves-Henri; Casman, Hélène; Verbeke, Alain (Eds.) Le droit des régimes matrimoniaux en pratique (2002)

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