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See detailApplication of Supercritical carbon dioxide for the preparation of drug-cyclodextrin inclusion compounds
Van Hees, Thierry ULg; Barillaro, Valery; Piel, Géraldine ULg et al

in Journal of Inclusion Phenomena and Macrocyclic Chemistry (2002), 44(1-4), 271-274

Inclusion complexes of drugs into cyclodextrins (CDs) can be obtained at the solid state by means of supercritical dioxide (SCCO2). A successful inclusion with a yield >98.5% has been achieved with ... [more ▼]

Inclusion complexes of drugs into cyclodextrins (CDs) can be obtained at the solid state by means of supercritical dioxide (SCCO2). A successful inclusion with a yield >98.5% has been achieved with piroxicam and beta-CD. The temperature and the time of exposure to SCCO2 have a significant effect on the inclusion yield while the pressure has a negative effect. However, there is a strong interaction between temperature and pressure and this interaction has a positive influence. The molar ratio piroxicam-beta-CD and the addition of ternary alkaline agents were also found to be significant factors. The dissolution rate of the complexes formed using SCCO2 was found to be significantly higher than that of the physical mixture. Inclusion complexes have also been obtained with miconazole treating mixtures of miconazole, CDs and citric acid by SCCO2. This new technique of inclusion of poorly soluble drugs into CDs allows the preparation of solid complexes without using organic solvents and thus without residues. [less ▲]

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See detailMyoglobinurie atypique chez les chevaux au pré
Delguste, Catherine ULg

Conference (2002, November 30)

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See detailComptes-rendus du symposium « Les acarioses cutanées des animaux de compagnie en dermatologie vétérinaire »
Mignon, Bernard ULg

Book published by Presses de la Faculté de Médecine Vétérinaire de l’Université de Liège (2002)

Detailed reference viewed: 19 (5 ULg)
See detailEntre Men et Asclépios : se soigner dans l'Asie Mineure antique
Nissen, Cécile ULg

Scientific conference (2002, November 30)

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See detailPolymer database for encapsulation
Grandfils, Christian ULg

Conference (2002, November 29)

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See detailDual effects of an extra disulfide bond on the activity and stability of a cold-adapted alpha-amylase
D'Amico, Salvino ULg; Gerday, Charles ULg; Feller, Georges ULg

in Journal of Biological Chemistry (2002), 277(48), 46110-46115

Chloride-dependent alpha-amylases constitute a well conserved family of enzymes thereby allowing investigation of the characteristics of each member to understand, for example, relevant properties ... [more ▼]

Chloride-dependent alpha-amylases constitute a well conserved family of enzymes thereby allowing investigation of the characteristics of each member to understand, for example, relevant properties required for environmental adaptation. In this context, we have constructed a double mutant (Q58C/A99C) of the cold-active and heat-labile alpha-amylase from the Antarctic bacterium Pseudoalteromonas haloplanktis, defined on the basis of its strong similarity with the mesophilic enzyme from pig pancreas. This mutant was characterized to understand the role of an extra disulfide bond specific to warm-blooded animals and located near the entrance of the catalytic cleft. We show that the catalytic parameters of the mutant are drastically modified and similar to those of the mesophilic enzyme. Calorimetric studies demonstrated that the mutant is globally stabilized (DeltaDeltaG = 1.87 kcal/mol at 20 degrees C) when compared with the wild-type enzyme, although the melting point (T-m) was not increased. Moreover, fluorescence quenching experiments indicate a more compact structure for the mutated a-amylase. However, the strain imposed on the active site architecture induces a 2-fold higher thermal inactivation rate at 45 degreesC as well as the appearance of a less stable calorimetric domain. It is concluded that stabilization by the extra disulfide bond arises from an enthalpy-entropy compensation effect favoring the enthalpic contribution. [less ▲]

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See detailLifetime measurements and calculations in singly ionized ytterbium
Biémont, Emile ULg; Quinet, Pascal ULg; Dai, Z. W. et al

in Journal of Physics B-Atomic Molecular and Optical Physics (2002), 35(22), 4743-4749

New radiative lifetimes, measured by time-resolved laser-induced fluorescence spectroscopy, are reported for five Rydberg states of singly ionized ytterbium. Free Yb+ ions were produced in a laser-induced ... [more ▼]

New radiative lifetimes, measured by time-resolved laser-induced fluorescence spectroscopy, are reported for five Rydberg states of singly ionized ytterbium. Free Yb+ ions were produced in a laser-induced plasma. The experimental results have been compared with HFR calculations, taking core-polarization effects into account, and a good agreement (within 25%) between theory and experiment is observed for four levels. HFR results are also proposed for np (n less than or equal to 7) and nf (n less than or equal to 8) Rydberg states and compared with available data. [less ▲]

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See detailThe influence of Space Weather and of the ionosphere on Global Navigation Satellite Systems
Warnant, René ULg; Jodogne, Jean-Claude; Nebdi, Hamid

Conference given outside the academic context (2002)

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See detailLe poids des Églises et des sectes au Congo-Kinshasa
Melice, Anne ULg

Conference given outside the academic context (2002)

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See detailLes orientations stratégiques de la Coopération Universitaire au Développement
Marchal, Jean ULg

(2002, November 28)

Chargée, dès 1997, à préparer et à mettre en œuvre les responsabilités nouvelles des universités francophones de Belgique dans le cadre de la coopération universitaire au développement, la C.U.D. n’a ... [more ▼]

Chargée, dès 1997, à préparer et à mettre en œuvre les responsabilités nouvelles des universités francophones de Belgique dans le cadre de la coopération universitaire au développement, la C.U.D. n’a cessé d’identifier, de définir, d’adapter, d’affiner ses orientations stratégiques. Ce processus a été celui d’un apprentissage continu : de nombreuses évaluations internes à la C.U.D., et à ses groupes de travail, une concertation continue avec les autorités publiques, le relais des institutions universitaires du sud, ont permis à la C.U.D. de consolider, tout au long de l’actuel plan quinquennal 1998-2002, les orientations stratégiques qui guident ses programmes et qui constitueront la base des travaux du prochain plan quinquennal. Dans la présente contribution, sont décrites très brièvement les principales orientations stratégiques qui servent de lignes directrices à la C.U.D. [less ▲]

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See detailQuelle est la place de la mémoire dans l'apprentissage du français langue seconde
Lucchini, Silvia ULg

Conference given outside the academic context (2002)

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See detailPerinatal Group B Streptococcal Disease Prevention, Interactive session
Melin, Pierrette ULg

Conference (2002, November 23)

Detailed reference viewed: 9 (1 ULg)
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See detailUne analyse exploratoire des effets des formations continues sur les salariés
Conter, Bernard; Maroy, Christian; Orianne, Jean-François ULg

Conference (2002, November 22)

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See detailUne analyse exploratoire des effets des formations continues sur les salariés
Conter, Bernard; Maroy, Christian; Orianne, Jean-François ULg

Conference (2002, November 22)

Detailed reference viewed: 8 (2 ULg)
See detailSameleven in the 21ste eeuw
Martiniello, Marco ULg

Scientific conference (2002, November 22)

Detailed reference viewed: 9 (0 ULg)
See detailContrôle des produits agroalimentaires par analyse d'images
Leemans, Vincent ULg; Kleynen, Olivier; Destain, Marie-France ULg

in Nouveaux capteurs pour la maîtrise de la qualité des produits agroalimentaires - Etat de la recherche européenne (2002, November 22)

Présentation de méthodes utilisées dans un processus de contrôle de qualité basé sur l'analyse d'image, en se focalisant sur la couleur et la forme des produits et leur classification

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See detailTraffic Effects of Driver Assistance Systems – The Approach within INVENT-VRA
Benz, T.; Christen, Fréderic ULg; Lerner, G. et al

in Telematik im Kraftfahrzeug (2002, November 21)

Within the German Research Initiative INVENT, the partial project „Verkehrliche Wirkung, Recht und Akzeptanz (VRA)“ deals with traffic effects, legal aspects, acceptance and economics of driver assistance ... [more ▼]

Within the German Research Initiative INVENT, the partial project „Verkehrliche Wirkung, Recht und Akzeptanz (VRA)“ deals with traffic effects, legal aspects, acceptance and economics of driver assistance systems. The major focus is to accompany the development of such systems rather than evaluating the systems at a later stage. This ensures that wrong development paths are avoided from the beginning. This presentation gives examples for the consulting services of VRA as well as for the early simulations of a driver assistance system. Such simulations vary in scale from basic functions to driving situations, then to traffic situations and finally to traffic scenarios. Results are presented for the basic functions and driving situations for a stop-and-go extension of adaptive cruise control. [less ▲]

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