References of "2001"
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See detailL’anémie : approche diagnostique et cas cliniques
Peeters, Dominique ULg

Conference (2001, November)

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See detailLa guerre et la medecine d'une culture de paix. 1. Quand s'ouvrent les portes du temple de janus
Pierard, Gérald ULg

in Revue Médicale de Liège (2001), 56(11), 785-7

More than 40 major wars took place during the past decade. The origins and the warlike means that were engaged were very different from those of older conflicts. Wars between nations are less numerous ... [more ▼]

More than 40 major wars took place during the past decade. The origins and the warlike means that were engaged were very different from those of older conflicts. Wars between nations are less numerous. They have been replaced by civilian wars that are more rooted on cultural and religious grounds than on economic interests alone. During this short period of time, warfare was responsible for about 2 millions of direct deaths and 20 millions displaced people and refugees. The injured and victims of starvation and epidemics were innumerable and awaited for civilian medical help. [less ▲]

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See detailL'image du mois. Un melanome masque chez un joueur de tennis
Fraiture, A. L.; Henry, Frédérique ULg; Pierard-Franchimont, Claudine ULg et al

in Revue Médicale de Liège (2001), 56(11), 737-8

A man presented with a malignant melanoma of the scalp. The lesion reached a large size before being disclosed. Repetitive sunburns during tennis matches could be responsible for this cancer. Indeed, hair ... [more ▼]

A man presented with a malignant melanoma of the scalp. The lesion reached a large size before being disclosed. Repetitive sunburns during tennis matches could be responsible for this cancer. Indeed, hair protects only partially the skin from ultraviolet damages. [less ▲]

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See detailNormal ranges for the variability in heart rate in young infants while sleeping
Massin, M. M.; Withofs, Nadia ULg; Maeyns, K. et al

in Cardiology in the Young (2001), 11(6), 619-625

Objective: Measurements of the variability in heart rate are increasingly used as markers of cardiac autonomic activity. We sought to establish the development this variability in healthy young infants ... [more ▼]

Objective: Measurements of the variability in heart rate are increasingly used as markers of cardiac autonomic activity. We sought to establish the development this variability in healthy young infants while sleeping. Patients: We carried out polygraphic studies with electrocardiographic recording in 587 healthy infants aged from 5 to 26 weeks. Methods: We determined several variables over a period of 400 minutes sleeping: mean RR interval, 5 time-domain (SDNN, SDNNi, SDANNi, RMSSD, and pNN50) and 5 frequency-domain indexes (spectral power over 3 regions of interest, total power and low-to-high frequency ratio). Frequency-domain indexes were also assessed separately for the periods of quiet sleep and those of rapid eye movement sleep. Results: Our data showed a significant correlation between the indexes of heart rate variability and the mean RR interval, the breathing rate, and the corrected age of the infants. We also demonstrated the importance of the maturation of the sleeping patterns. Conclusion: These data in a large cohort of healthy infants confirm a progressive maturation of the autonomic nervous system during sleep, and may be used to examine the influence of physiological and pathophysiological factors on autonomic control during polygraphic studies. [less ▲]

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See detailLabyrinthine Granular Landscapes
Caps, Hervé ULg; Vandewalle, Nicolas ULg

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2001), 64(5, Pt 1), 52301

We have numerically studied a model of granular landscape eroded by wind. We show the appearance of labyrinthic patterns when the wind orientation turns by 90 degrees. The occurrence of such structures is ... [more ▼]

We have numerically studied a model of granular landscape eroded by wind. We show the appearance of labyrinthic patterns when the wind orientation turns by 90 degrees. The occurrence of such structures is discussed. Moreover, we introduce the density n(k) of "defects" as the dynamic parameter governing the landscape evolution. A power-law behavior of n(k) is found as a function of time. In the case of wind variations, the exponent (drastically) shifts from two to one. The presence of two asymptotic values of n(k) implies the irreversibility of the labyrinthic formation process. [less ▲]

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See detailRelationship between maternal concentrations of caprine pregnancy-associated glycoprotein in Alpine goats and the number of fetuses using a homologous radioimmunoassay
Batalha, E. S.; Sulon, Joseph ULg; Figueiredo, J. R. et al

in Small Ruminant Research (2001), 42(2), 105-109

The relationship between maternal caprine pregnancy-associated glycoprotein (cPAG) concentrations and fetal number was investigated in 21 nulliparous and 17 multiparous goats. Using a homologous ... [more ▼]

The relationship between maternal caprine pregnancy-associated glycoprotein (cPAG) concentrations and fetal number was investigated in 21 nulliparous and 17 multiparous goats. Using a homologous radioimmunoassay (hm-RIA) cPAG was detected in plasma of pregnant goats from the 21st day of pregnancy. Statistical differences between goats bearing single and multiple fetuses were observed after 63 days to the end of pregnancy, except on day 133. After 126 days (3rd week pre-partum) cPAG levels began to decrease slowly in both the groups. The hm-RIA was an efficient method to describe the relationship between maternal PAO concentrations and number of fetuses in goats. (C) 2001 Published by Elsevier Science B.V. [less ▲]

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See detailPlasma profile of pregnancy associated glycoprotein (PAG) in pregnant Alpine goats using two radioimmunoassay (RIA) systems
Batalha, E. S.; Sulon, Joseph ULg; Figueiredo, J. R. et al

in Small Ruminant Research (2001), 42(2), 111-118

This paper evaluates the profiles obtained for caprine pregnancy associated glycoprotein (cPAG) in pregnant multiparous and nulliparous goats using the heterologous-radioimmunoassay (htPAG-RIA) and the ... [more ▼]

This paper evaluates the profiles obtained for caprine pregnancy associated glycoprotein (cPAG) in pregnant multiparous and nulliparous goats using the heterologous-radioimmunoassay (htPAG-RIA) and the homologous-RIA (hmPAG-RIA) systems during the pregnancy and postpartum periods. The results show that the cPAG concentrations detected through the hmPAG-RIA procedure were lower than those found through the htPAG-RIA method. No statistical differences were observed due to the maternal reproductive status (nulliparous or multiparous goats) during pregnancy using either one of the methods. However, pregnant and cyclic goats were distinguished from each other by cPAG concentrations verified through the hmPAG-RIA procedure. The lower cPAG concentrations detected through this method suggest that this system is more specific than the htPAG-RIA procedure to measure cPAG during pregnancy and postpartum period in goats. The homologous system was also an efficient method to predict pregnancies of only 35 days in both nulliparous and multiparous goats. (C) 2001 Published by Elsevier Science B.V. [less ▲]

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See detailPresentation anatomo-clinique. Terato-carcinome testiculaire avec adenopathies thoraco-abdominales
Dassy, S.; Coibion-Jossa, V.; Demelenne, A. et al

in Revue Médicale de Liège (2001), 56(11), 777-84

This case report of a young man with a testicular germ cell-teratoma tumor illustrates the necessity of a multidisciplinary sequential approach to ensure chance of cure. The outcome of patients with ... [more ▼]

This case report of a young man with a testicular germ cell-teratoma tumor illustrates the necessity of a multidisciplinary sequential approach to ensure chance of cure. The outcome of patients with advanced germ cell tumor depends on the optimal clinical management. Residual masses are frequent, and their histology can be different than the initial one (i.e., only residual mature teratoma cells or necrosis-fibrosis). Therefore a second surgery on residual masses with curative intent, may be important to optimalize the treatment and follow up. [less ▲]

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See detailModélisation mathématique de simulation des crues de la Chiers amont à l’aide des modèles MHM et MOHICAN
Bourouag, Mohamed ULg; Dzisiak, J. P.; Everbecq, Etienne ULg et al

Report (2001)

En 1999, l’Association Intercommunale pour la Valorisation de l’Eau (AIVE) a confié à l’Université de Liège (Laboratoire de Géologie de l’Ingénieur, d’Hydrogéologie et de Prospection géophysique (LGIH-ULG ... [more ▼]

En 1999, l’Association Intercommunale pour la Valorisation de l’Eau (AIVE) a confié à l’Université de Liège (Laboratoire de Géologie de l’Ingénieur, d’Hydrogéologie et de Prospection géophysique (LGIH-ULG), Laboratoire d’Hydrodynamique appliquée (HYD-ULG), Centre d’Etude et de Modélisation de l’Environnement (CEME-ULG)), à la Faculté Universitaire des Sciences Agronomiques de Gembloux (Unité d’Hydraulique Agricole) et à l’Université Catholique de Louvain (Unité de Génie rural (GERU-UCL)), la mission de réaliser des modélisations mathématiques de simulations des crues de la CHIERS amont à l’aide des modèles MHM et MOHICAN. Le modèle MHM (« Modèle Hydrologique Maillé ») a été développé par l’Unité de Génie rural de l’UCL. Le modèle MOHICAN (« Modèle hydrologique intégré pour le calcul des crues et l’amplitude des niveaux d’eau ») a été développé conjointement par l’Université de Liège (Laboratoire d’hydrodynamique appliquée, Laboratoire de Géologie de l’Ingénieur et d’Hydrogéologie, Centre d’Etude et de Modélisation de l’environnement) et la Faculté Universitaire des Sciences Agronomiques de Gembloux Louvain (Unité d’Hydraulique agricole) pour le compte et avec le support du Ministère de l’Equipement et des Transports, Service d’Etudes Hydrologiques (MET/SETHY) de la Région wallonne. Le MET a donné l’autorisation d’utiliser le modèle MOHICAN dans le cadre de l’étude hydrologique de la CHIERS. L’étude est organisée en 3 étapes : (i) Elaboration des bases de données et exécution des modèles, (ii) Réalisation de tests des modèles et calibration et (iii) Simulation de scénarios. Le présent rapport présente d’abord le modèle MHM (chapitre 2) et le modèle MOHICAN (chapitre 3) ainsi que les bases de données nécessaires à leur utilisation (chapitre 4 : bases de données pour MHM, chapitre 5 : bases de données pour MOHICAN). Les premières étapes de simulation (phase de calibration et de validation) sont présentées au chapitre 6 (Modélisation MHM – Calibration/Validation) et au chapitre 7 (Modélisation MOHICAN – Calibration/Validation). Enfin, les simulations ont été réalisées : - pour le bassin de la Messancy à Athus, d’une superficie de 68 km² environ; - pour le bassin de la Chiers à Longlaville, représentant un bassin versant de 157 km² environ (comprenant le bassin de la Messancy). Ces simulations réalisées sur base de différents scénarios d’aménagement du bassin de la Chiers amont sont présentées au chapitre 8 (Modélisation MHM – Scénarios) et au chapitre 9 (Modélisation MOHICAN – Scénarios). [less ▲]

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See detailLes coûts de la désurbanisation
Halleux, Jean-Marie ULg

Conference given outside the academic context (2001)

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See detailBiosystems Engineering: Applying methods from systems theory to biological systems
Kremling, A.; Sauter, T.; Bullinger, Eric ULg et al

in Proc. of the 3rd International Conference on Systems Biology (2001, November)

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See detailPathologies surrénaliennes
Peeters, Dominique ULg; Remy, Isabelle ULg

in Proceedings du congrès CNVSPA-SAVAB (2001, November)

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See detailGenesis of Clone Size Heterogeneity in Megakaryocytic and Other Hemopoietic Colonies: The Stochastic Model Revisited
Paulus, Jean-Michel ULg; Levin, J.; Debili, N. et al

in Experimental Hematology (2001), 29(11), 1256-69

OBJECTIVE: We previously showed that the distributions of the numbers of doublings (NbD) undergone by individual megakaryocyte progenitors before commitment to polyploidization are markedly skewed and can ... [more ▼]

OBJECTIVE: We previously showed that the distributions of the numbers of doublings (NbD) undergone by individual megakaryocyte progenitors before commitment to polyploidization are markedly skewed and can consistently be fitted to straight lines when plotted on semilogarithmic coordinates. The slope of such lines, which yields the probability of polyploidization per doubling, is made less steep by stimulators of megakaryocyte colony formation and is less steep in mixed erythroid-megakaryocyte than in pure megakaryocyte colonies. Therefore, megakaryocytopoiesis provides a unique model for the study of clonal heterogeneity in a hemopoietic lineage, which is the subject of this review. DATA SOURCES: Articles relevant to the interpretation of these data were selected from the authors' and public databases. DATA SYNTHESIS: Exponential NbD distributions were first explained by postulating that following the assembly of thrombopoiesis-specific regulators, megakaryocyte progenitors require only a single random event to arrest proliferation and commit to polyploidization. However, this stochastic model was refuted by data indicating that intrinsic properties of individual progenitors affect the NbD they achieve. We suggest that the unequal repartition of critical compounds (including receptors, signaling molecules, and gene regulators) inherent in the stem cell-progenitor transition causes a heritable heterogeneity in megakaryocyte progenitor responsiveness to polyploidization inducers. This model would be compatible with 1) the evidence for intraclonal synchronization in megakaryocyte and other hemopoietic clones generated by committed progenitors; 2) the low probability of polyploidization of the relatively insensitive bipotent megakaryocyte progenitors; and 3) the thesis that stimulators act in part by recruiting megakaryocyte progenitor cells endowed with lesser responsiveness to polyploidization inducers and higher proliferative potential. CONCLUSION: The responsiveness of individual megakaryocyte progenitors to polyploidization inducers may be a major determinant of the exponential shape of NbD distributions. [less ▲]

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See detailPathologies surrénaliennes
Peeters, Dominique ULg

in Proceedings of "Congrès CNVSPA-SAVAB" (2001, November)

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See detailPharma-clinics comment je traite ... une infection par le VIH. IV. Les inhibiteurs de protease
Leonard, Philippe ULg; Nkoghe, D.; Moutschen, Michel ULg et al

in Revue Médicale de Liège (2001), 56(11), 739-44

Protease inhibitors constitute the last class of antiretroviral drugs appeared on the market. They raised an enormous enthusiasm, reinforced by recent studies results. These molecules prevent the ... [more ▼]

Protease inhibitors constitute the last class of antiretroviral drugs appeared on the market. They raised an enormous enthusiasm, reinforced by recent studies results. These molecules prevent the formation of infectious viral particles, while inhibiting a viral enzyme that plays a key role in the cycle of replication of the HIV. Their efficiency, especially in association, is recognized for all stages of the infection and the intervening of a resistance often requires many mutations. However, the unexpected adverse events such as lipodystrophy and some interactions can limit their utilization in first intention. [less ▲]

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See detailDobutamine Stress Echocardiography Versus Quantitative Technetium-99m Sestamibi Spect for Detecting Residual Stenosis and Multivessel Disease after Myocardial Infarction
LANCELLOTTI, Patrizio ULg; Benoit, T.; Rigo, Pierre ULg et al

in Heart (2001), 86(5), 510-5

OBJECTIVE: To compare the relative accuracy of dobutamine stress echocardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting ... [more ▼]

OBJECTIVE: To compare the relative accuracy of dobutamine stress echocardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting infarct related artery stenosis and multivessel disease early after acute myocardial infarction. DESIGN: Prospective study. SETTING: University hospital. METHODS: 75 patients underwent simultaneous DSE and mibi SPECT at (mean (SD)) 5 (2) days after a first acute myocardial infarct. Quantitative coronary angiography was performed in all patients after imaging studies. RESULTS: Significant stenosis (> 50%) of the infarct related artery was detected in 69 patients. Residual ischaemia was identified by DSE in 55 patients and by quantitative mibi SPECT in 49. The sensitivity of DSE and mibi SPECT for detecting significant infarct related artery stenosis was 78% and 70%, respectively, with a specificity of 83% for both tests. The combination of DSE and mibi SPECT did not change the specificity (83%) but increased the sensitivity to 94%. Mibi SPECT was more sensitive than DSE for detecting mild stenosis (73% v 9%; p = 0.008). The sensitivity of DSE for detecting moderate or severe stenosis was greater than mibi SPECT (97% v 74%; p = 0.007). Wall motion abnormalities with DSE and transient perfusion defects with mibi SPECT outside the infarction zone were sensitive (80% v 67%; NS) and highly specific (95% v 93%; NS) for multivessel disease. CONCLUSIONS: DSE and mibi SPECT have equivalent accuracy for detecting residual infarct related artery stenosis of >/= 50% and multivessel disease early after acute myocardial infarction. DSE is more predictive of moderate or severe infarct related artery stenosis. Combined imaging only improves the detection of mild stenosis. [less ▲]

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