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See detailEarly Stage Results after Oesophageal Resection for Malignancy - Colon Interposition Vs. Gastric Pull-Up
Kolh, Philippe ULg; Honore, Pierre ULg; Degauque, C. et al

in European Journal of Cardio - Thoracic Surgery (2000), 18(3), 293-300

OBJECTIVE: The aims of our study were to determine if using the colon as a digestive transplant after oesophagectomy for cancer was associated with increased postoperative complications, and to assess the ... [more ▼]

OBJECTIVE: The aims of our study were to determine if using the colon as a digestive transplant after oesophagectomy for cancer was associated with increased postoperative complications, and to assess the impact of preoperative radiochemotherapy on postoperative hospital outcome. METHODS: From January 1990 to December 1998, 130 patients underwent oesophageal resection for malignancy. There were 103 males and 27 females (age: 61.3+/-11.5 years). Indications were squamous cell carcinoma in 69 patients and adenocarcinoma in 61. Preoperatively 30 patients (eight in stage IIB, 18 in stage III, and four in stage IV) received radiochemotherapy. There were 84 subtotal oesophagectomies, with anastomosis in the neck in 44 patients and at the thoracic inlet in 40, and 46 distal oesophageal resections. Digestive continuity was restored with the stomach in 92 patients (age: 63.4+/-10.2 years) and the colon in 38 (age: 52.3+/-12.8 years). With the exception of age (P<0.0001), there was no significant preoperative difference between gastric and colonic groups. RESULTS: Hospital mortality was 8.5% (11 patients), decreasing from 18.5% (before 1993) to 3.8% (since 1993). One patient (2.5%) died in the colonic graft group and ten (11%) in the gastric pull-up group (P=0.17). Postoperative complications occurred in 40 patients (31%), respectively, in ten (26%) and 30 (33%) patients after colonic and gastric transplants (P=0.48), and were pulmonary insufficiency or infection in 29 patients, anastomotic fistula in six, myocardial infarction in five, recurrent nerve palsy in four, renal insufficiency in three, and cerebrovascular accident in one. All fistulas occurred in the gastric pull-up group. The incidence of postoperative pulmonary complications was 70% (21/30 patients) in the subgroup who received preoperative radiochemotherapy, as compared to 11% (5/44 patients) in the subgroup of comparable staging, but without preoperative treatment (P<0.001). CONCLUSIONS: Colonic grafts are not associated with increased postoperative mortality or complications. Our results suggest that preoperative neoadjuvant treatment significantly increases postoperative pulmonary complications. [less ▲]

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See detailLeast Cost and Scantling Optimization at the initial Design Stage of Ships
Rigo, Philippe ULg; Toderan, Catalin

in ICETECH 2000 (2000, September)

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See detailInv(12)(Q15q24): A Nonrandom Change Associated with Myelodysplasia?
Scantamburlo, Gabrielle ULg; Lampertz, serge; Jamar, Michelle ULg et al

in Cancer Genetics & Cytogenetics (2000), 121(2), 206-7

A patient with refractory anemia and a paracentric inversion of chromosome 12, inv(12)(q15q24), is described. This is the second reported case with this chromosome anomaly, suggesting that this ... [more ▼]

A patient with refractory anemia and a paracentric inversion of chromosome 12, inv(12)(q15q24), is described. This is the second reported case with this chromosome anomaly, suggesting that this rearrangement is a rare but nonrandom change associated with myelodysplastic syndromes. [less ▲]

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See detailOxobenzopyran derivatives as thrombin inhibitors
Bourdel, F.; Lacan, F.; Doucet, C. et al

Poster (2000, September)

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See detailA potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin release
Antoine, M. H.; Arkhammar, P.; Nguyen, Q. A. et al

Poster (2000, September)

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See detailAdaptive λ-tracking for Systems with Higher Relative Degree
Bullinger, Eric ULg

Doctoral thesis (2000)

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See detailInhibition of cellular invasion by 3-chlorophenyl 6-(acetoxymethyl)-2-oxo-2H-1-benzopyran-3-carboxylate
Kempen, I.; Pochet, L.; Papapostulu, D. et al

Poster (2000, September)

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See detailEffect on the pancreatic endocrine system of 3-alkylamino-7-chloro-4H-1,2,4-benzothiadiazine 1,1-dioxides structurally related to diazoxide
Boverie, S.; Antoine, M. H.; Becker, B. et al

Poster (2000, September)

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See detailOntogeny of Aromatase and Tyrosine Hydroxylase Activity and of Aromatase-Immunoreactive Cells in the Preoptic Area of Male and Female Japanese Quail
Balthazart, Jacques ULg; Tlemcani, O.; Harada, N. et al

in Journal of Neuroendocrinology (2000), 12(9), 853-66

The aromatization of testosterone into oestrogens plays a key role in the control of many behavioural and physiological aspects of reproduction. In the quail preoptic area (POA), aromatase activity and ... [more ▼]

The aromatization of testosterone into oestrogens plays a key role in the control of many behavioural and physiological aspects of reproduction. In the quail preoptic area (POA), aromatase activity and the number of aromatase-immunoreactive (ARO-ir) cells are sexually differentiated (males > females). This sex difference is implicated in the control of the sexually dimorphic behavioural response of quail to testosterone. We analysed the ontogenetic development of this sex difference by measuring aromatase activity and counting ARO-ir cells in the POA of males and females from day 1 post hatch to sexual maturity. We investigated in parallel another enzyme: tyrosine hydroxylase, the rate limiting step in catecholamine synthesis. Between hatching and 4 weeks of age, aromatase activity levels were low and equal in males and females. Aromatase activity then markedly increased in both sexes when subjects initiated their sexual maturation but this increase was more pronounced in males so that a marked difference in aromatase activity was present in 6 and 8 week-old subjects. Tyrosine hydroxylase activity progressively increased with age starting immediately after hatching and there was no abrupt modification in the slope of this increase when birds became sexually mature. No sex difference was detected in the activity of this enzyme. The number of ARO-ir cells in the POA progressively increased with age starting at hatching. No sex difference in ARO-ir cell numbers could be detected before subjects reached full sexual maturity. The analysis of the three-dimensional organization of ARO-ir cells in the POA revealed that, with increasing ages, ARO-ir cells acquire a progressively more lateral position: they are largely periventricular in young birds but they are found at higher density in the lateral part of the medial preoptic nucleus in adults. These data indicate that aromatase activity differentiates sexually when birds reach sexual maturity presumably under the activating effects of the increased testosterone levels in males. The number of ARO-ir cells, however, begins to increase in a non sexually differentiated manner before the rise in plasma testosterone in parallel with the increased tyrosine hydroxylase activity. Whether this temporal coincidence results from a general ontogenetic pattern or from more direct causal links remains to be established. [less ▲]

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See detailTatouages. Du rituel a la parure avec leurs complications
Paquet, Philippe ULg; Pierard, Gérald ULg; Nikkels, Arjen ULg et al

in Revue Médicale de Liège (2000), 55(9), 847-849

Tattoos are performed for distinct purposes which range from social rituals to aesthetic aims. They are permanent or transient according to the site of the pigments being located either in the dermis or ... [more ▼]

Tattoos are performed for distinct purposes which range from social rituals to aesthetic aims. They are permanent or transient according to the site of the pigments being located either in the dermis or in the stratum corneum, respectively. Tattoos may be responsible for allergic reactions, infections or psychological distress of the subject who requests to be relieved of it. [less ▲]

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See detailTernary polymer blend with core-shell dispersed phases: effect of the core-forming polymer on phase morphology and mechanical properties
Luzinov, Igor; Pagnoulle, Christophe; Jérôme, Robert ULg

in Polymer (2000), 41(19), 7099-7109

Phase morphology and mechanical properties of ternary blends consisting of PS (polystyrene), SBR (styrene butadiene rubber) and different polyolefins (POs) have been studied. PS, systematically forms the ... [more ▼]

Phase morphology and mechanical properties of ternary blends consisting of PS (polystyrene), SBR (styrene butadiene rubber) and different polyolefins (POs) have been studied. PS, systematically forms the matrix, SBR and PO being combined in the dispersed phase. Although POs of various melt viscosity and stiffness are used, the binary (SBR/PO) dispersed phase is of a core-shell structure, in which PO forms the core. Upon increasing the viscosity of PO, the average size of the cores and the SBR domains including them increases. Comparison of the experimental shear storage modulus of the blends with theoretical predictions indicates that the stress transfer from the PS matrix to the PO core through the SBR shell depends on the modulus of the SBR envelope. The ultimate mechanical properties of the ternary blends are sensitive to the stiffness of the PO core. [less ▲]

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See detailOn the link between design against fatigue and fracture mechanics
Debongnie, Jean-François ULg

in ASME (Ed.) Proceedings of the 2000 ASME Design Engineering Technical Conferences (2000, September)

The gradient method, often used in design against fatigue, is analyzed from the point of view of its link with fracture mechanics. By a logical step, a law is deduced for the variation of the endurance ... [more ▼]

The gradient method, often used in design against fatigue, is analyzed from the point of view of its link with fracture mechanics. By a logical step, a law is deduced for the variation of the endurance limit in terms of the relative stress gradient. The proposed expression is found to be in good agreement with older ones and may easily be extended to a large class of materials. [less ▲]

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See detailL'union libre et la réparation des accidents mortels de travail
Michiels, Olivier ULg

in Divorce : Actualité Juridique, Sociale et Fiscale (2000), 9

L'article s'attache à la question de l'indemnisation du compagnon ou de la campagne d'un travailleur qui décède au cours d'un accident du travail.

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See detailVoxel-based distribution of metabolic impairment in corticobasal degeneration
Garraux, Gaëtan ULg; Salmon, Eric ULg; Peigneux, Philippe ULg et al

in Movement Disorders (2000), 15(5), 894-904

This report emphasizes the precise topographic distribution of cerebral metabolic impairment in corticobasal degeneration (CBD) and the pathophysiological differences between CBD and progressive ... [more ▼]

This report emphasizes the precise topographic distribution of cerebral metabolic impairment in corticobasal degeneration (CBD) and the pathophysiological differences between CBD and progressive supranuclear palsy (PSP). Statistical parametric mapping (SPM96) analysis of 18FDG positron emission tomography (PET) data was performed in 22 patients with CBD compared with 46 healthy subjects (HS) and 21 patients with PSP who were studied at rest. A statistical threshold of p <0.001 was fixed, further corrected for multiple or independent comparisons (p <0.05). In comparison with HS, the metabolic impairment in CBD was asymmetrically distributed in the putamen, thalamus, precentral (Brodmann's area, BA 4), lateral premotor (BA 6/44) and supplementary motor areas (SMA, BA 6), dorsolateral prefrontal (8/9/46) cortex, and the anterior part of the inferior parietal lobe (BA 40) including the intraparietal sulcus (BA 7/40). A similar hypometabolic pattern was observed for most individual analyses. When PSP was compared with CBD, metabolic impairment predominated in the midbrain, anterior cingulate (BA 24/32), and orbitofrontal regions (BA 10). The reverse contrast showed more posterior involvement in CBD (BA 6 and 5/7/40) including SMA. Our data suggest that multiple components of neural networks related to both movement execution and production of skilled movements are functionally disturbed in CBD compared with both HS and PSP. [less ▲]

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See detailAn agent-inspired active network resource trading model applied to congestion control
Yamamoto, Lidia; Leduc, Guy ULg

in Lecture Notes in Computer Science (2000, September), 1931

In order to accommodate fluctuations in network conditions, adaptive applications need to obtain information about resource availability, Using active networks, new models for adaptive applications can be ... [more ▼]

In order to accommodate fluctuations in network conditions, adaptive applications need to obtain information about resource availability, Using active networks, new models for adaptive applications can be envisaged, which can benefit from the possibility to send mobile code to the network nodes. We describe a model for trading resources inside an active net-work node, based on the interaction between capsules as reactive user agents, and resource manager agents which reside in the network nodes. We apply the model to the case of a many-to-one audio application with congestion control, which trades off link resources against memory when there is congestion at the outgoing interface towards the destination. Our simulation results indicate that the application makes effective use of the available resources, and it also allows resources to be shared according to user preferences. [less ▲]

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